OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Pharmaceutical Analysis is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Printability–A key issue in extrusion-based bioprinting	132
Curcumin encapsulated dual cross linked sodium alginate/montmorillonite polymeric composite beads for controlled drug delivery	100
Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and nanotechnology	82
Recent advances in quantum dots-based biosensors for antibiotics detection	72
Interactions between gut microbiota and berberine, a necessary procedure to understand the mechanisms of berberine	70
Challenges for cysteamine stabilization, quantification, and biological effects improvement	63
Phytochemicals targeting NF-κB signaling: Potential anti-cancer interventions	63
Towards wearable and implantable continuous drug monitoring: A review	61
Physicochemical degradation of phycocyanin and means to improve its stability: A short review	59
Development of chromatographic technologies for the quality control of Traditional Chinese Medicine in the Chinese Pharmacopoeia	59
Carbon dots derived from Poria cocos polysaccharide as an effective “on-off” fluorescence sensor for chromium (VI) detection	58
Chemically modified carbon-based electrodes for the determination of paracetamol in drugs and biological samples	56
Development of the general chapters of the Chinese Pharmacopoeia 2020 edition: A review	55
Tumor cell membrane-coated continuous electrochemical sensor for GLUT1 inhibitor screening	55
Bi2O3/ZnO nanocomposite: Synthesis, characterizations and its application in electrochemical detection of balofloxacin as an anti-biotic drug	54
Offline two-dimensional liquid chromatography coupled with ion mobility-quadrupole time-of-flight mass spectrometry enabling four-dimensional separation and characterization of the multicomponents fro	53
Recent advances in research on vine tea, a potential and functional herbal tea with dihydromyricetin and myricetin as major bioactive compounds	53
Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches	46
Anti-inflammatory and analgesic properties of Moroccan medicinal plants: Phytochemistry, in vitro and in vivo investigations, mechanism insights, clinical evidences and perspectives	46
Solid phase microextraction chemical biopsy tool for monitoring of doxorubicin residue during in vivo lung chemo-perfusion	45
Screening strategies for quorum sensing inhibitors in combating bacterial infections	45
Electrochemical detection of methyl-paraoxon based on bifunctional cerium oxide nanozyme with catalytic activity and signal amplification effect	44
The current status of anti-GPCR drugs against different cancers	41
Antiviral, immunomodulatory, and anticoagulant effects of quercetin and its derivatives: Potential role in prevention and management of COVID-19	41
Neutrophil elastase: From mechanisms to therapeutic potential	40

Machine learning empowered COVID-19 patient monitoring using non-contact sensing: An extensive review	39
Current developments of bioanalytical sample preparation techniques in pharmaceuticals	38
A sensitive electrochemical detection of metronidazole in synthetic serum and urine samples using low-cost screen-printed electrodes modified with reduced graphene oxide and C60	38
Neuroprotective effects of Ginkgo biloba dropping pills in Parkinson’s disease	38
Biocompatible silver nanoparticles: An investigation into their protein binding efficacies, anti-bacterial effects and cell cytotoxicity studies	37
Qualitative and quantitative evaluation of Flos Puerariae by using chemical fingerprint in combination with chemometrics method	36
Qualitative analysis of chemical components in Lianhua Qingwen capsule by HPLC-Q Exactive-Orbitrap-MS coupled with GC-MS	36
Rabdosia serra alleviates dextran sulfate sodium salt-induced colitis in mice through anti-inflammation, regulating Th17/Treg balance, maintaining intestinal barrier integrity, and modulating gut micr	36
Potential treatment with Chinese and Western medicine targeting NSP14 of SARS-CoV-2	33
Comparison of different approaches for direct coupling of solid-phase microextraction to mass spectrometry for drugs of abuse analysis in plasma	33
Evaluation of apoptotic effects of mPEG-b-PLGA coated iron oxide nanoparticles as a eupatorin carrier on DU-145 and LNCaP human prostate cancer cell lines	32
Antimicrobial activity and mode of action of terpene linalyl anthranilate against carbapenemase-producing Klebsiella pneumoniae	32
Multimodal integrated strategy for the discovery and identification of quality markers in traditional Chinese medicine	32
Transformation of berberine to its demethylated metabolites by the CYP51 enzyme in the gut microbiota	31
An ultra-robust fingerprinting method for quality assessment of traditional Chinese medicine using multiple reaction monitoring mass spectrometry	30
Applications and challenges of low temperature plasma in pharmaceutical field	30
Applications and safety of gold nanoparticles as therapeutic devices in clinical trials	29
Integrative multi-omics and systems bioinformatics in translational neuroscience: A data mining perspective	28
Overoxidized poly(3,4-ethylenedioxythiophene)–gold nanoparticles–graphene-modified electrode for the simultaneous detection of dopamine and uric acid in the presence of ascorbic acid	27
Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and senescence	27
DNA barcoding in herbal medicine: Retrospective and prospective	27
Microneedle-based interstitial fluid extraction for drug analysis: Advances, challenges, and prospects	26
Capillary electrophoresis methods for impurity profiling of drugs: A review of the past decade	26
Nitrogen-doped carbon@TiO2 double-shelled hollow spheres as an electrochemical sensor for simultaneous determination of dopamine and paracetamol in human serum and saliva	26
Dispersive liquid-liquid microextraction, an effective tool for the determination of synthetic cannabinoids in oral fluid by liquid chromatography–tandem mass spectrometry	26
Diallyl disulfide and diallyl trisulfide in garlic as novel therapeutic agents to overcome drug resistance in breast cancer	26
Fluorescent aptasensor for detection of live foodborne pathogens based on multicolor perovskite-quantum-dot-encoded DNA probes and dual-stirring-bar-assisted signal amplification	25
Identification and quantification of the bioactive components in Osmanthus fragrans roots by HPLC-MS/MS	24
18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs	23
Celastrol targeting Nedd4 reduces Nrf2-mediated oxidative stress in astrocytes after ischemic stroke	23
Metabolomic and elemental profiling of blood serum in bladder cancer	23
A dual-signal sensor for the analysis of parathion-methyl using silver nanoparticles modified with graphitic carbon nitride	22
An LC-MS/MS method for simultaneous analysis of the cystic fibrosis therapeutic drugs colistin, ivacaftor and ciprofloxacin	22
Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid	22
Diversity, novelty, antimicrobial activity, and new antibiotics of cultivable endophytic actinobacteria isolated from psammophytes collected from Taklamakan Desert	22
Screening of immune cell activators from Astragali Radix using a comprehensive two-dimensional NK-92MI cell membrane chromatography/C18 column/time-of-flight mass spectrometry system	21
A strategy of screening and binding analysis of bioactive components from traditional Chinese medicine based on surface plasmon resonance biosensor	20
In situ synthesis of a spherical covalent organic framework as a stationary phase for capillary electrochromatography	20
Accurate and sensitive determination of hydroxychloroquine sulfate used on COVID-19 patients in human urine, serum and saliva samples by GC-MS	19
Reversible regulation of enzyme-like activity of molybdenum disulfide quantum dots for colorimetric pharmaceutical analysis	19
RETRACTED: A DNA-based nanocarrier for efficient cancer therapy	19
Determination of bioactive components in the fruits of Cercis chinensis Bunge by HPLC-MS/MS and quality evaluation by principal components and hierarchical cluster analyses	19
Liquid chromatographic methods for determination of the new antiepileptic drugs stiripentol, retigabine, rufinamide and perampanel: A comprehensive and critical review	19
Highly sensitive electrochemical determination of rutin based on the synergistic effect of 3D porous carbon and cobalt tungstate nanosheets	18
Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors	18
MIL-53-based homochiral metal-organic framework as a stationary phase for open-tubular capillary electrochromatography	18
Molecular detection of SARS-CoV-2 being challenged by virus variation and asymptomatic infection	18
Recent progress in aptamer-based microfluidics for the detection of circulating tumor cells and extracellular vesicles	18
Automatic analytical approach for the determination of 12 illicit drugs and nicotine metabolites in wastewater using on-line SPE-UHPLC-MS/MS	18
Comparative analysis of constitutes and metabolites for traditional Chinese medicine using IDA and SWATH data acquisition modes on LC-Q-TOF MS	18

Development of an analytical method for multi-residue quantification of 18 anthelmintics in various animal-based food products using liquid chromatography-tandem mass spectrometry	17
Pharmacokinetics, distribution, and excretion of sodium oligomannate, a recently approved anti-Alzheimer's disease drug in China	17
Metabolomics-based comparative analysis of the effects of host and environment on Viscum coloratum metabolites and antioxidative activities	17
Design and preparation of a new multi-targeted drug delivery system using multifunctional nanoparticles for co-delivery of siRNA and paclitaxel	17
Single-run reversed-phase HPLC method for determining sertraline content, enantiomeric purity, and related substances in drug substance and finished product	17
Synthesis and electrochemical properties of environmental free l-glutathione grafted graphene oxide/ZnO nanocomposite for highly selective piroxicam sensing	17
Development of a radiolabeled site-specific single-domain antibody positron emission tomography probe for monitoring PD-L1 expression in cancer	17
Identification of potential anti-pneumonia pharmacological components of Glycyrrhizae Radix et Rhizoma after the treatment with Gan An He Ji oral liquid	17
Discovery of human pancreatic lipase inhibitors from root of Rhodiola crenulata via integrating bioactivity-guided fractionation, chemical profiling and biochemical assay	16
Advances and challenges in using nirmatrelvir and its derivatives against SARS-CoV-2 infection	16
Erythrocyte sphingolipid species as biomarkers of Alzheimer's disease	16
Recent trends of machine learning applied to multi-source data of medicinal plants	16
The potential of miRNA-based therapeutics in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: A review	16
Predicting the grades of Astragali radix using mass spectrometry-based metabolomics and machine learning	16
Study of intracellular anabolism of 5-fluorouracil and incorporation in nucleic acids based on an LC-HRMS method	16
A highly efficient protein corona-based proteomic analysis strategy for the discovery of pharmacodynamic biomarkers	16
Natural product-based radiopharmaceuticals: Focus on curcumin and its analogs, flavonoids, and marine peptides	16
Metabolomics: A useful tool for ischemic stroke research	15
Anti-inflammatory natural products modulate interleukins and their related signaling markers in inflammatory bowel disease: A systematic review	15
Protecting future antimalarials from the trap of resistance: Lessons from artemisinin-based combination therapy (ACT) failures	15
Human islet amyloid polypeptide: A therapeutic target for the management of type 2 diabetes mellitus	15
Compatibility and stability studies involving polymers used in fused deposition modeling 3D printing of medicines	15
Boosting ferroptosis and microtubule inhibition for antitumor therapy via a carrier-free supermolecule nanoreactor	15
Visualizing the spatial distribution and alteration of metabolites in continuously cropped Salvia miltiorrhiza Bge using MALDI-MSI	15
Ginsenoside Rk3 is a novel PI3K/AKT-targeting therapeutics agent that regulates autophagy and apoptosis in hepatocellular carcinoma	15
Drug repurposing against coronavirus disease 2019 (COVID-19): A review	15
Preparation of Fe3O4@SW-MIL-101-NH2 for selective pre-concentration of chlorogenic acid metabolites in rat plasma, urine, and feces samples	14
Combination immunotherapy of glioblastoma with dendritic cell cancer vaccines, anti-PD-1 and poly I:C	14
Ultrasensitive quantification of trace amines based on N-phosphorylation labeling chip 2D LC-QQQ/MS	14
Sensitive detection of microRNAs using polyadenine-mediated fluorescent spherical nucleic acids and a microfluidic electrokinetic signal amplification chip	14
Metabolomic fingerprinting of porcine lung tissue during pre-clinical prolonged ex vivo lung perfusion using in vivo SPME coupled with LC-HRMS	14
Detection and quantitation of host cell proteins in monoclonal antibody drug products using automated sample preparation and data-independent acquisition LC-MS/MS	14
Resveratrol elongates the lifespan and improves antioxidant activity in the silkworm Bombyx mori	14
Effects and translatomics characteristics of a small-molecule inhibitor of METTL3 against non-small cell lung cancer	14
A preparation strategy for protein-oriented immobilized silica magnetic beads with Spy chemistry for ligand fishing	13
Recent applications and chiral separation development based on stationary phases in open tubular capillary electrochromatography (2019–2022)	13
Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases	13
Three-dimensional aspects of formulation excipients in drug discovery: a critical assessment on orphan excipients, matrix effects and drug interactions	13
Simultaneous enantioseparation and simulation studies of atenolol, metoprolol and propranolol on Chiralpak® IG column using supercritical fluid chromatography	13
Angiotensin-converting enzyme 2 as a potential therapeutic target for COVID-19: A review	13
Probing the degradation of pharmaceuticals in urine using MFC and studying their removal efficiency by UPLC-MS/MS	13
Current diagnostic and therapeutic strategies for COVID-19	13
Neurotoxicity mechanism of aconitine in HT22 cells studied by microfluidic chip-mass spectrometry	12
A simplified LC-MS/MS method for the quantification of the cardiovascular disease biomarker trimethylamine-N-oxide and its precursors	12
Taxifolin stability: In silico prediction and in vitro degradation with HPLC-UV/UPLC–ESI-MS monitoring	12
UHPLC-MS/MS analysis of cAMP and cGMP in rat plasma as potential biomarkers of Yin-Yang disharmony in traditional Chinese medicine	12
A highly sensitive bio-barcode immunoassay for multi-residue detection of organophosphate pesticides based on fluorescence anti-quenching	12
Herb-drug interaction in the protective effect of Alpinia officinarum against gastric injury induced by indomethacin based on pharmacokinetic, tissue distribution and excretion studies in rats	12
Plasma-metabolite-based machine learning is a promising diagnostic approach for esophageal squamous cell carcinoma investigation	12
Reducing SARS-CoV-2 pathological protein activity with small molecules	12
Single-cell analyses reveal cannabidiol rewires tumor microenvironment via inhibiting alternative activation of macrophage and synergizes with anti-PD-1 in colon cancer	12
Identifying the molecular basis of Jinhong tablets against chronic superficial gastritis via chemical profile identification and symptom-guided network pharmacology analysis	12
A chiral metal-organic framework {(HQA)(ZnCl2)(2.5H2O)}n for the enantioseparation of chiral amino acids and drugs	12
Development of a surface plasmon resonance biosensor for accurate and sensitive quantitation of small molecules in blood samples	12
Impaired tricarboxylic acid cycle flux and mitochondrial aerobic respiration during isoproterenol induced myocardial ischemia is rescued by bilobalide	12
Application of microfluidic technology based on surface-enhanced Raman scattering in cancer biomarker detection: A review	12
Fast saccharide mapping method for quality consistency evaluation of commercial xylooligosaccharides collected in China	11
Novel insights into histone lysine methyltransferases in cancer therapy: From epigenetic regulation to selective drugs	11
An integrated strategy for comprehensive characterization of metabolites and metabolic profiles of bufadienolides from Venenum Bufonis in rats	11
Design, synthesis, and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors	11
Tumor-targeting intravenous lipid emulsion of paclitaxel: Characteristics, stability, toxicity, and toxicokinetics	11
Dissecting the brain with spatially resolved multi-omics	11
Characterization of multiple chemical components of GuiLingJi by UHPLC-MS and 1H NMR analysis	11
Rapid fabrication of zwitterionic sulfobetaine vinylimidazole-based monoliths via photoinitiated copolymerization for hydrophilic interaction chromatography	11
Polarity-regulated derivatization-assisted LC-MS method for amino-containing metabolites profiling in gastric cancer	11
Long-chain alkanol–alkyl carboxylic acid-based low-viscosity hydrophobic deep eutectic solvents for one-pot extraction of anthraquinones from Rhei Radix et Rhizoma	11
Effective extraction of fluoroquinolones from water using facile modified plant fibers	10
Rapid metabolic fingerprinting with the aid of chemometric models to identify authenticity of natural medicines: Turmeric, Ocimum, and Withania somnifera study	10
Novel assays for quality evaluation of XueBiJing: Quality variability of a Chinese herbal injection for sepsis management	10
Effects of polyol excipient stability during storage and use on the quality of biopharmaceutical formulations	10
Novel wine in an old bottle: Preventive and therapeutic potentials of andrographolide in atherosclerotic cardiovascular diseases	10
GB7 acetate, a galbulimima alkaloid from Galbulimima belgraveana, possesses anticancer effects in colorectal cancer cells	10
Influence of traditional Chinese medicines on the in vivo metabolism of lopinavir/ritonavir based on UHPLC-MS/MS analysis	10
Fabrication of edge-curled petals-like covalent organic frameworks and their properties for extracting indole alkaloids from complex biological samples	10
Comprehensive metabolic profiling of Alismatis Rhizoma triterpenes in rats based on characteristic ions and a triterpene database	10
In vivo solid phase microextraction for therapeutic monitoring and pharmacometabolomic fingerprinting of lung during in vivo lung perfusion of FOLFOX	10
SPME as a green sample-preparation technique for the monitoring of phytocannabinoids and endocannabinoids in complex matrices	10
Use of subcutaneous tocilizumab to prepare intravenous solutions for COVID-19 emergency shortage: Comparative analytical study of physicochemical quality attributes	10
Analysis of anticancer compound, indole-3-carbinol, in broccoli using a new ultrasound-assisted dispersive-filter extraction method based on poly(deep eutectic solvent)-graphene oxide nanocomposite	10