OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Pharmaceutical Investigation is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Nitric oxide-releasing albumin/chondroitin sulfate bioadhesive dressing for the treatment of MRSA-infected wounds	223
Effects of telmisartan and perindopril combination on hypertension and cardiovascular damage	100
Emerging metabolic hormone therapeutics for metabolic dysfunction-associated steatohepatitis: incretin-based drugs, fibroblast growth factor analogs, and liver-targeting strategies	77
Applications of mesoporous silica particles in amorphous solid dispersion	67
Enhanced oral bioavailability of pranlukast by preparing amorphous solid dispersion via hot-melt extrusion	51
Development of prediction model with machine learning in continuous twin screw granulation	43
The combination of HDACi encapsulated liposomal vaccines with oncolytic peptide QR-KLU induces an immune-mediated abscopal effect for cancer immunotherapy	40
Recent advances in 3D cell culture models in cancer drug development	39
Recent advances in Alzheimer’s disease pathogenesis and therapeutics from an immune perspective	37
Comprehensive review in continuous direct compression process	32
Biocompatible biodegradable polymeric nanocarriers in dry powder inhalers (DPIs) for pulmonary inhalation delivery	29
Pharmacokinetic modulation of substrate drugs via the inhibition of drug-metabolizing enzymes and transporters using pharmaceutical excipients	28
Recent progress in drying technologies for improving the stability and delivery efficiency of biopharmaceuticals	27
Enhanced oral delivery of fenofibrate using PEGylated solid lipid nanoparticles	27
Self-amplifying ROS nanoplatform with dual responsiveness for tumor-targeted photodynamic therapy	27
uPAR-targeted senolytic delivery to enhance cancer therapy	26
Organic clay-based fast dissolving microneedles for efficient transdermal delivery of therapeutic proteins	24
Prediction of the pharmacokinetics of the GLP-1 receptor agonist semaglutide in humans via a population pharmacokinetic model integrating interspecies scaling	24
Lyophilization of pharmaceuticals: an overview and practical approaches for developing the lyophilization cycle	23
A two-step design of experiments approach to investigate the simultaneous effects of ion-pairing and chemical enhancers to improve the permeability of lornoxicam in a topical hydrogel patch	22
Theranostic potential and safety assessment of epirubicin-loaded SPIONs/PLGA-PEG nanoparticles in rabbit	21
Formulation of secretome derived from mesenchymal stem cells for inflammatory skin diseases	21
Can label-free flow-imaging microscopy based on morphological parameters be used to quantitatively analyze NK–cells?	20
Effect of krill oil incorporation into phospholipid bilayers on the stability and cellular effects of curcumin encapsulated in liposomes	20
Transferrin modified PEG–PLGA nanoparticles: highly effective notoginsenoside R1 formulations for the treatment of ulcerative colitis	19

Effects of red ginseng extract on the pharmacokinetics and disposition of warfarin via intestinal Cyp2c11 modulation in rats	19
Integrative nanoparticulate strategies with SEDDS for controlled drug release: from lipid platforms to smart delivery systems	18
Gold nanoparticles prevent the establishment of severe malaria in a murine animal model	18
Enhanced oral bioavailability of megestrol acetate via polymer-hybridized solid lipid nanoparticles using ultrasonic nebulization method	18
Preformulation and evaluation of multi-layer tablets	17
Meta-analysis of levamisole absorption and disposition across diverse species using a minimal physiologically-based pharmacokinetic model	16
Antimicrobial strategies for topical biofilm-based wound infections: past, present, and future	16
A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function	16
Topical nanomedicines using lipids, carbohydrates, proteins, and synthetic polymers for enhanced management of skin disorders	16
Strategic design and clinical evaluation of a fixed-dose combination tablet comprising valsartan, amlodipine, rosuvastatin and ezetimibe for patients with hypertension and dyslipidemia	15
Emerging trends in quantum dot-based photosensitizers for enhanced photodynamic therapy in cancer treatment	15
Indocyanine green-loaded microspheres as a near-infrared fluorescence marker for long-term localization of tumor sites	15
Mesenchymal stem cell-based therapeutics for chronic wound healing: from biological potential to programmable pharmaceutical modalities	15
Development and in vitro/in vivo evaluation of a nanosponge formulation loaded with Boswellia carterii oil extracts for the enhanced anti-inflammatory activity for the management of respiratory allerg	14
Advancements of hot-melt extrusion technology to address unmet patient needs and pharmaceutical quality aspects	13
Polysaccharide-based platforms for nasal delivery: design, features, and perspectives	13
Tumor extracellular vesicles carrying antitumor (KLAKLAK)2 peptide and tumor-specific antigens for improved tumor therapy	13
Modern approaches to quality by design for amorphous solid dispersion product development: a narrative review	13
Injectable hydrogel systems for local cancer therapy	13
Oral bioavailability enhancement of chrysin using a spray-dried solid dispersion formulation with sodium dodecyl sulfate and polyvinylpyrrolidone	13
Development of core–shell structured nanoparticle for sequential release of tariquidar and docetaxel to overcome multi drug-resistant cancer	12
Cationic lipid nanoparticles for nucleic acid delivery: microfluidics versus thin film hydration	12
Fusion nanoparticle system of extracellular vesicles and docetaxel-loaded liposomes: an innovative therapeutic strategy to enhance anticancer efficacy	12
Integration of modern science into herbal medicine: application of pharmacokinetic-pharmacodynamic modeling in understanding nonclinical study of Cinnamomum cassia extract.	11
Novel microneedle patches for transdermal delivery of AP39, a hydrogen sulphide donor, in the treatment of scenarios mimicking neurological disorders	11
Liquisolid powders of Andrographis paniculata extract: physicochemical attributes, dissolution, oral bioavailability, stability, and acute toxicity	11
Amorphous lactose solid dispersion co-spray-dried with magnesium stearate as a novel lactose carrier for dry powder inhalers	11
Safety of applying influenza-antigen-coated microneedles to rat skin and the antigen specific immune response in vivo	10
Current trends in inhaled pharmaceuticals: challenges and opportunities in respiratory infections treatment	10
Pharmacokinetic/pharmacodynamic modeling of therapeutic antibodies in oncology: current advances and future perspectives	10
Development and evaluation of flurbiprofen plasters	10
ROS-activated prodrug nano-assemblies based on cinnamaldehyde-modified paclitaxel for treating breast cancer	9
Advanced technology using supercritical fluid for particle production in pharmaceutical continuous manufacturing	9
Permeability enhancer incorporated oral nanosuspension of ARV-825 PROTAC for Glioblastoma treatment	9
Advances in transdermal delivery systems using polysaccharide-based natural enhancers: mechanisms and clinical potential	9
A combination formulation of TPGS micelles loaded with paclitaxel and olaparib and a pH-thermosensitive hydrogel for treating peritoneal metastasis and drug-resistant ovarian cancer	9
Iron oxide nanoparticles-loaded hydrogels for effective topical photothermal treatment of skin cancer	9
RETRACTED ARTICLE: A review of recent advances in nanotechnology for the delivery of therapeutics in wound healing	9
Nitric oxide-releasing albumin nanoclusters facilitate healing of methicillin-resistant Staphylococcus aureus-infected cutaneous wounds	9