OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Pharmaceutical Investigation is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Microneedle for transdermal drug delivery: current trends and fabrication	139
Recent advances of nanocellulose in drug delivery systems	69
Factors influencing drug deposition in the nasal cavity upon delivery via nasal sprays	54
Characterization studies of novel series of cobalt (II), nickel (II) and copper (II) complexes: DNA binding and antibacterial activity	47
Physical properties of nanoparticles do matter	40
Nanomedicine-based commercial formulations: current developments and future prospects	37
Mitochondrial targeted strategies and their application for cancer and other diseases treatment	34
Recent developments in cancer therapy and diagnosis	34
Controlled release and targeted drug delivery with poly(lactic-co-glycolic acid) nanoparticles: reviewing two decades of research	33
Emerging nanoparticulate drug delivery systems of metformin	31
Drug delivery to the brain via the nasal route of administration: exploration of key targets and major consideration factors	30
Cellulose and its derivatives for application in 3D printing of pharmaceuticals	30
Comparison of solubility enhancement by solid dispersion and micronized butein and its correlation with in vivo study	29
Application of conductive poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) polymers in potential biomedical engineering	28
Nanomedicine-based antimicrobial peptide delivery for bacterial infections: recent advances and future prospects	28
Fabrication of aerosol-based nanoparticles and their applications in biomedical fields	28
Smart pH-responsive nanomedicines for disease therapy	27
Development of clindamycin-loaded alginate/pectin/hyaluronic acid composite hydrogel film for the treatment of MRSA-infected wounds	27
Recent progress in cancer immunotherapy approaches based on nanoparticle delivery devices	26
Recent trends of self-emulsifying drug delivery system for enhancing the oral bioavailability of poorly water-soluble drugs	26
Multifunctional lipidic nanocarriers for effective therapy of glioblastoma: recent advances in stimuli-responsive, receptor and subcellular targeted approaches	25
Intestinal membrane transporter-mediated approaches to improve oral drug delivery	24
Recent progress in hydrophobic ion-pairing and lipid-based drug delivery systems for enhanced oral delivery of biopharmaceuticals	21
Recent advancements in lipid–mRNA nanoparticles as a treatment option for cancer immunotherapy	21
Lipid-based nanoparticles for photosensitive drug delivery systems	19

Nanoparticles of ZnO/Berberine complex contract COVID-19 and respiratory co-bacterial infection in addition to elimination of hydroxychloroquine toxicity	19
Development of amphotericin B nanosuspensions for fungal keratitis therapy: effect of self-assembled γ-cyclodextrin	17
Development of oral aprepitant-loaded chitosan–polyethylene glycol-coated cyclodextrin nanocapsules: formulation, characterization, and pharmacokinetic evaluation	17
Pharmaceutical application and development of fixed-dose combination: dosage form review	17
Response surface optimization of self nano-emulsifying drug delivery system of rosuvastatin calcium for hepatocellular carcinoma	17
Recent advances in nano/microparticle-based oral vaccines	16
Effects of lipid nanoparticles on physicochemical properties, cellular uptake, and lymphatic uptake of 6-methoxflavone	15
Proliposome powder or tablets for generating inhalable liposomes using a medical nebulizer	15
Selenium nanostructure: Progress towards green synthesis and functionalization for biomedicine	15
Exemestane encapsulated copolymers L121/F127/GL44 based mixed micelles: solubility enhancement and in vitro cytotoxicity evaluation using MCF-7 breast cancer cells	14
Development of topical natural based film forming system loaded propolis from stingless bees for wound healing application	14
Active targeting via ligand-anchored pH-responsive strontium nanoparticles for efficient nucleic acid delivery into breast cancer cells	14
Microemulsion as a promising carrier for nose to brain delivery: journey since last decade	13
Micronization of a poorly water-soluble drug, fenofibrate, via supercritical-fluid-assisted spray-drying	13
Tumor spheroid-based microtumor models for preclinical evaluation of anticancer nanomedicines	13
Iron oxide nanoparticles-loaded hydrogels for effective topical photothermal treatment of skin cancer	13
Development of immunotherapy and nanoparticles-based strategies for the treatment of Parkinson’s disease	12
Progress and recent trends in photodynamic therapy with nanoparticles	12
Ultra deformable vesicles for boosting transdermal delivery of 2-arylpropionic acid class drug for management of musculoskeletal pain	12
A comprehensive review on different approaches for tumor targeting using nanocarriers and recent developments with special focus on multifunctional approaches	12
pH-sensitive beads containing curcumin loaded nanostructured lipid carriers for a colon targeted oral delivery system	12
Recent progress in drying technologies for improving the stability and delivery efficiency of biopharmaceuticals	11
Recent studies on modulating hyaluronic acid-based hydrogels for controlled drug delivery	11
Thermosensitive nasal in situ gelling systems of rufinamide formulated using modified tamarind seed xyloglucan for direct nose-to-brain delivery: design, physical characterization, and in vivo evaluat	11
Quality by Design (QbD) application for the pharmaceutical development process	11
Development of a zero-order kinetics drug release floating tablet with anti–flip-up design fabricated by 3D-printing technique	11
Three-Dimensional Printing for Oral Pharmaceutical Dosage Forms	11
Anti-inflammatory effects of a topical emulsion containing Helianthus annuus oil, glycerin, and vitamin B3 in mice	11
Ameliorative potential of Sterculia tragacantha aqueous extract on renal gene expression and biochemical parameters in streptozotocin-induced diabetic rats	10
Microneedle systems for delivering nucleic acid drugs	10
A comparative evaluation of anti-tumor activity following oral and intravenous delivery of doxorubicin in a xenograft model of breast tumor	10
Population pharmacokinetic analysis of lornoxicam in healthy Korean males considering creatinine clearance and CYP2C9 genetic polymorphism	10
Potential therapeutic and pharmacological strategies for SARS-CoV2	10
Simple determination and quantification of tofacitinib, a JAK inhibitor, in rat plasma, urine and tissue homogenates by HPLC and its application to a pharmacokinetic study	9
A quality by design approach in oral extended release drug delivery systems: where we are and where we are going?	9
Statistical design of experiment-based formulation development and optimization of 3D printed oral controlled release drug delivery with multi target product profile	9
Replacement techniques to reduce animal experiments in drug and nanoparticle development	9
Current perspectives of artificial oxygen carriers as red blood cell substitutes: a review of old to cutting-edge technologies using in vitro and in vivo assessments	9
5-[(3-Carboxy-4-hydroxyphenyl)diazenyl] nicotinic acid, an azo-linked mesalazine-nicotinic acid conjugate, is a colon-targeted mutual prodrug against dextran sulfate sodium-induced colitis in mice	8
Bacteriophages: cancer diagnosis, treatment, and future prospects	8
Application of mechanism-based modeling to predict drug quality during the pharmaceutical unit operations of granulation and compression: a review	8
Erythromycin dermal delivery by MoS2 nanoflakes	8
Evaluating the efficacy of different curcumin polymorphs in transdermal drug delivery	8
Dose-independent pharmacokinetics of loganin in rats: effect of intestinal first-pass metabolism on bioavailability	8
Distribution of “molybdenum disulfide/cobalt ferrite” nanocomposite in animal model of breast cancer, following injection via differential infusion flow rates	7
Graphene-based nanomaterial system: a boon in the era of smart nanocarriers	7
Alginate-coated chitosan nanoparticles protect protein drugs from acid degradation in gastric media	7
High frequency ultrasound mediated transdermal delivery of ondansetron hydrochloride employing bilosomal gel systems: ex-vivo and in-vivo characterization studies	7
Ophthalmic dosage forms for drug delivery to posterior segment	7
Surface modification strategies for high-dose dry powder inhalers	7

Oral cavity: An open horizon for nanopharmaceuticals	6
Bilayer tablets with sustained-release metformin and immediate-release sitagliptin: preparation and in vitro/in vivo evaluation	6
Effects of 1α,25-dihydroxyvitamin D3 on the pharmacokinetics and biodistribution of ergothioneine, an endogenous organic cation/carnitine transporter 1 substrate, in rats	6
Recent advances in the formulation of sphingolipid anticancer therapeutics	6
Design and synthesis of potential nano-carrier for delivery of diphencyprone to hair follicle	6
The effects of combined treatment of losartan and ramipril on hypertension and related complications	6
Nanomedicine approaches for medulloblastoma therapy	6
Pharmacokinetics and hypoglycemic effect of gliclazide loaded in Isabgol husk mucilage microparticles	6
In vivo evaluation of biodistribution and toxicity of pH-responsive strontium nanoparticles for gene delivery	6
Orodispersible film incorporating nanoparticulate loratadine for an enhanced oral bioavailability	6
Treatment of Wilms’ nephroblastoma cancer cells via EGFR targeting of dactinomycin loaded DNA-nanowires	6
Advanced technology using supercritical fluid for particle production in pharmaceutical continuous manufacturing	5
Gene regulations and delivery vectors for treatment of cancer	5
An overview of chondrosarcoma with a focus on nanoscale therapeutics	5
Formulation of sustained-release orodispersible film containing drug–resin complexes of donepezil hydrochloride	5
Regulation of drug transporters by microRNA and implications in disease treatment	5
Quality by design approach to the development of transdermal patch systems and regulatory perspective	5
In vitro and in vivo evaluations of a 3-month sustained-release microsphere depot formulation of leuprolide acetate	5
Effect of gastric residence time on the oral absorption of rebamipide sustained-release tablets in beagle dogs	4
An economically advantageous amorphous solid dispersion of the fixed combination of lopinavir and ritonavir	4
Dissolving microneedle arrays that compensated for skin water loss due to microporation	4
Tumor-originated pH-responsive nanovaccine mixture to treat heterogeneous tumors	4
Tableting process-induced solid-state polymorphic transition	4
Mitigating off-target distribution and enhancing cytotoxicity in breast cancer cells with alpha-ketoglutaric acid-modified Fe/Mg-CA nanoparticles	4
Physicochemical analysis techniques specialized in surface characterization of inhalable dry powders	4
Intratympanic drug delivery systems to treat inner ear impairments	4
Tumor extracellular vesicles carrying antitumor (KLAKLAK)2 peptide and tumor-specific antigens for improved tumor therapy	4
Design of experiment (DoE)-based formulation design of bepotastine sustained-release tablet and in vitro-in vivo pharmacokinetic correlation	4
Establishment of a fexofenadine population pharmacokinetic (PK)–pharmacodynamic (PD) model and exploration of dosing regimens through simulation	4
Formulation development and pharmacokinetic evaluation of enteric-coated dexrabeprazole tablets	4
Pharmacokinetic modulation of substrate drugs via the inhibition of drug-metabolizing enzymes and transporters using pharmaceutical excipients	4