OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Pharmaceutical Investigation is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Microneedle for transdermal drug delivery: current trends and fabrication	185
Nanomedicine-based commercial formulations: current developments and future prospects	74
Drug delivery to the brain via the nasal route of administration: exploration of key targets and major consideration factors	55
Characterization studies of novel series of cobalt (II), nickel (II) and copper (II) complexes: DNA binding and antibacterial activity	53
Controlled release and targeted drug delivery with poly(lactic-co-glycolic acid) nanoparticles: reviewing two decades of research	48
Fabrication of aerosol-based nanoparticles and their applications in biomedical fields	40
Smart pH-responsive nanomedicines for disease therapy	39
Recent trends of self-emulsifying drug delivery system for enhancing the oral bioavailability of poorly water-soluble drugs	35
Nanomedicine-based antimicrobial peptide delivery for bacterial infections: recent advances and future prospects	33
Development of clindamycin-loaded alginate/pectin/hyaluronic acid composite hydrogel film for the treatment of MRSA-infected wounds	31
Multifunctional lipidic nanocarriers for effective therapy of glioblastoma: recent advances in stimuli-responsive, receptor and subcellular targeted approaches	30
Recent progress in hydrophobic ion-pairing and lipid-based drug delivery systems for enhanced oral delivery of biopharmaceuticals	28
Intestinal membrane transporter-mediated approaches to improve oral drug delivery	27
Recent progress in cancer immunotherapy approaches based on nanoparticle delivery devices	26
Recent advancements in lipid–mRNA nanoparticles as a treatment option for cancer immunotherapy	25
Lipid-based nanoparticles for photosensitive drug delivery systems	24
Nanoparticles of ZnO/Berberine complex contract COVID-19 and respiratory co-bacterial infection in addition to elimination of hydroxychloroquine toxicity	22
Recent progress in drying technologies for improving the stability and delivery efficiency of biopharmaceuticals	21
Pharmaceutical application and development of fixed-dose combination: dosage form review	20
Selenium nanostructure: Progress towards green synthesis and functionalization for biomedicine	19
Development of oral aprepitant-loaded chitosan–polyethylene glycol-coated cyclodextrin nanocapsules: formulation, characterization, and pharmacokinetic evaluation	19
Current perspectives of artificial oxygen carriers as red blood cell substitutes: a review of old to cutting-edge technologies using in vitro and in vivo assessments	18
Development of immunotherapy and nanoparticles-based strategies for the treatment of Parkinson’s disease	18
Quality by Design (QbD) application for the pharmaceutical development process	18
Iron oxide nanoparticles-loaded hydrogels for effective topical photothermal treatment of skin cancer	17

Development of a zero-order kinetics drug release floating tablet with anti–flip-up design fabricated by 3D-printing technique	17
Recent advances in nano/microparticle-based oral vaccines	17
A comprehensive review on different approaches for tumor targeting using nanocarriers and recent developments with special focus on multifunctional approaches	17
Recent studies on modulating hyaluronic acid-based hydrogels for controlled drug delivery	17
Three-Dimensional Printing for Oral Pharmaceutical Dosage Forms	16
Thermosensitive nasal in situ gelling systems of rufinamide formulated using modified tamarind seed xyloglucan for direct nose-to-brain delivery: design, physical characterization, and in vivo evaluat	15
Exemestane encapsulated copolymers L121/F127/GL44 based mixed micelles: solubility enhancement and in vitro cytotoxicity evaluation using MCF-7 breast cancer cells	15
Micronization of a poorly water-soluble drug, fenofibrate, via supercritical-fluid-assisted spray-drying	15
Effects of lipid nanoparticles on physicochemical properties, cellular uptake, and lymphatic uptake of 6-methoxflavone	15
pH-sensitive beads containing curcumin loaded nanostructured lipid carriers for a colon targeted oral delivery system	14
Active targeting via ligand-anchored pH-responsive strontium nanoparticles for efficient nucleic acid delivery into breast cancer cells	14
A quality by design approach in oral extended release drug delivery systems: where we are and where we are going?	14
Microneedle systems for delivering nucleic acid drugs	14
Tumor spheroid-based microtumor models for preclinical evaluation of anticancer nanomedicines	14
Progress and recent trends in photodynamic therapy with nanoparticles	13
Ameliorative potential of Sterculia tragacantha aqueous extract on renal gene expression and biochemical parameters in streptozotocin-induced diabetic rats	13
Microemulsion as a promising carrier for nose to brain delivery: journey since last decade	13
Ophthalmic dosage forms for drug delivery to posterior segment	12
Anti-inflammatory effects of a topical emulsion containing Helianthus annuus oil, glycerin, and vitamin B3 in mice	12
A comparative evaluation of anti-tumor activity following oral and intravenous delivery of doxorubicin in a xenograft model of breast tumor	12
Ultra deformable vesicles for boosting transdermal delivery of 2-arylpropionic acid class drug for management of musculoskeletal pain	12
Graphene-based nanomaterial system: a boon in the era of smart nanocarriers	11
Quality by design approach to the development of transdermal patch systems and regulatory perspective	11
Erythromycin dermal delivery by MoS2 nanoflakes	10
Alginate-coated chitosan nanoparticles protect protein drugs from acid degradation in gastric media	10
Population pharmacokinetic analysis of lornoxicam in healthy Korean males considering creatinine clearance and CYP2C9 genetic polymorphism	10
Potential therapeutic and pharmacological strategies for SARS-CoV2	10
Statistical design of experiment-based formulation development and optimization of 3D printed oral controlled release drug delivery with multi target product profile	10
Dose-independent pharmacokinetics of loganin in rats: effect of intestinal first-pass metabolism on bioavailability	9
In vivo evaluation of biodistribution and toxicity of pH-responsive strontium nanoparticles for gene delivery	8
In vitro and in vivo evaluations of a 3-month sustained-release microsphere depot formulation of leuprolide acetate	8
Surface modification strategies for high-dose dry powder inhalers	8
Bilayer tablets with sustained-release metformin and immediate-release sitagliptin: preparation and in vitro/in vivo evaluation	8
Orodispersible film incorporating nanoparticulate loratadine for an enhanced oral bioavailability	8
Nanomedicine approaches for medulloblastoma therapy	8
Advanced technology using supercritical fluid for particle production in pharmaceutical continuous manufacturing	8
5-[(3-Carboxy-4-hydroxyphenyl)diazenyl] nicotinic acid, an azo-linked mesalazine-nicotinic acid conjugate, is a colon-targeted mutual prodrug against dextran sulfate sodium-induced colitis in mice	8
Effects of 1α,25-dihydroxyvitamin D3 on the pharmacokinetics and biodistribution of ergothioneine, an endogenous organic cation/carnitine transporter 1 substrate, in rats	8
Peptide permeation enhancers for improving oral bioavailability of macromolecules	8
Design and synthesis of potential nano-carrier for delivery of diphencyprone to hair follicle	7
Tableting process-induced solid-state polymorphic transition	7
Recent developments in dry powder inhalation (DPI) formulations for lung-targeted drug delivery	7
Treatment of Wilms’ nephroblastoma cancer cells via EGFR targeting of dactinomycin loaded DNA-nanowires	7
Oral cavity: An open horizon for nanopharmaceuticals	7
Amorphous nasal powder advanced performance: in vitro/ex vivo studies and correlation with in vivo pharmacokinetics	7
Formulation development and pharmacokinetic evaluation of enteric-coated dexrabeprazole tablets	6
Tumor-originated pH-responsive nanovaccine mixture to treat heterogeneous tumors	6
Design of experiment (DoE)-based formulation design of bepotastine sustained-release tablet and in vitro-in vivo pharmacokinetic correlation	6
Recent progress and drug delivery applications of surface-functionalized inorganic nanoparticles in cancer therapy	6
Intratympanic drug delivery systems to treat inner ear impairments	6

Pharmacokinetics and hypoglycemic effect of gliclazide loaded in Isabgol husk mucilage microparticles	6
Formulation of sustained-release orodispersible film containing drug–resin complexes of donepezil hydrochloride	6
Regulation of drug transporters by microRNA and implications in disease treatment	6
Synthesis, physicochemical properties, and protective effects of a novel water-soluble tetrahydrocurcumin-diglutaric acid prodrug on ethanol-induced toxicity in HepG2 cells	6
Effect of gastric residence time on the oral absorption of rebamipide sustained-release tablets in beagle dogs	5
Development of core–shell structured nanoparticle for sequential release of tariquidar and docetaxel to overcome multi drug-resistant cancer	5
Recent developments in chemodrug-loaded nanomedicines and their application in combination cancer immunotherapy	5
Antimicrobial strategies for topical biofilm-based wound infections: past, present, and future	5
Pharmacokinetic modulation of substrate drugs via the inhibition of drug-metabolizing enzymes and transporters using pharmaceutical excipients	5
Tumor extracellular vesicles carrying antitumor (KLAKLAK)2 peptide and tumor-specific antigens for improved tumor therapy	5
Dissolving microneedle arrays that compensated for skin water loss due to microporation	5
Solid dispersion of mebendazole via surfactant carrier to improve oral bioavailability and in vitro anticancer efficacy	5
A comprehensive review of nanosuspension loaded microneedles: fabrication methods, applications, and recent developments	4
Pharmacokinetic aspects of the clinically used proteasome inhibitor drugs and efforts toward nanoparticulate delivery systems	4
Catalase-mimicking synthetic nano-enzymes can reduce lipopolysaccharide-induced reactive oxygen generation and promote rapid detection of hydrogen peroxide and l-cysteine	4
Nitric oxide-releasing albumin nanoclusters facilitate healing of methicillin-resistant Staphylococcus aureus-infected cutaneous wounds	4
Polyamide 6/tallow modified clay nanofibrous mat coupled with hydrogels for potential topical/transdermal delivery of doxycycline hydrochloride	4
Recent advances in Alzheimer’s disease pathogenesis and therapeutics from an immune perspective	4
Regulatory and safe-use considerations related to stability after opening of nonsterile dosage forms	4
An economically advantageous amorphous solid dispersion of the fixed combination of lopinavir and ritonavir	4
A mechanism-based understanding of altered drug pharmacokinetics by gut microbiota	4
Establishment of a fexofenadine population pharmacokinetic (PK)–pharmacodynamic (PD) model and exploration of dosing regimens through simulation	4
Formulation of secretome derived from mesenchymal stem cells for inflammatory skin diseases	4
Quality by design approach with multivariate analysis and artificial neural network models to understand and control excipient variability	4
Application of continuous manufacturing for solid oral dosage forms	4
Mitigating off-target distribution and enhancing cytotoxicity in breast cancer cells with alpha-ketoglutaric acid-modified Fe/Mg-CA nanoparticles	4
Physicochemical analysis techniques specialized in surface characterization of inhalable dry powders	4
Sustained ocular delivery of desmopressin acetate via thermoreversible in situ gel formulation: preparation and in vitro/in vivo evaluation	3
Impact of buffer concentration on the thermal stability of immunoglobulin G	3
Population pharmacokinetic modeling and simulation of choline in healthy Korean subjects after oral administration of choline alfoscerate	3
Development of prediction model with machine learning in continuous twin screw granulation	3
The combined effects of telmisartan and ramipril on hypertension and cardiovascular injury	3
The embodiment of the strategy of “using active chemicals as excipients” in compound preparation	3
Polysaccharide-based platforms for nasal delivery: design, features, and perspectives	3
Strategies for developing Alzheimer’s disease treatments: application of population pharmacokinetic and pharmacodynamic models	3
Transferrin modified PEG–PLGA nanoparticles: highly effective notoginsenoside R1 formulations for the treatment of ulcerative colitis	3
Effects of polyvinylpyrrolidone (K90) on membrane permeation via the transcellular route in the rat jejunum	3
Size matters: differential property of hyaluronan and its fragments in the skin- relation to pharmacokinetics, immune activity and wound healing	3
Camellia sinesis leaves extract ameliorates high fat diet-induced nonalcoholic steatohepatitis in rats: analysis of potential mechanisms	3