OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Neurogastroenterology and Motility is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
A New Analysis for Old Problem of Bile Reflux	46
Association Between the Cool Temperature-dependent Suppression of Colonic Peristalsis and Transient Receptor Potential Melastatin 8 Activation in Both a Randomized Clinical Trial and an Animal Model	41
Hypercontractile Esophagus: Clinical and Manometric Features From a Multicenter Korean Cohort	41
The Use of Intraoperative Esophageal Functional Luminal Imaging Probe for Prediction of Therapeutic Outcomes in Achalasia Patients	38
Breaking Barriers in Functional Dyspepsia: A Systematic Review and Meta-analysis on Duodenal Tight Junction Protein Expression	33
Effect of Anti-reflux Mucosal Ablation on Esophageal Motility in Patients With Gastroesophageal Reflux Disease: A Study Based on High-resolution Impedance Manometry	30
Real-world Application of the Chicago Classification Version 4.0 for Esophageal Manometry: Asian Multicenter Study	30
Achalasia: The Current Clinical Dilemma and Possible Pathogenesis	26
Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study	26
Spot Hydrogen Breath Test: A Great Hockey Player Plays Where the Puck Is Going to Be	25
Ambulatory Impedance-pH Assessment Is the Industry Standard But Is It Always the Best Choice?	24
Irritable Bowel Syndrome-like Symptoms in Patients With Ulcerative Colitis in Remission as Compared to Irritable Bowel Syndrome: Symptom Severity and Inflammatory Markers	24
Validation of the London Classification for Rectal Hyposensitivity in an Anorectal Manometry Database of 2540 Patients With Functional Defecatory Disorder	23
Revisiting the Role of Esophageal Mucosal Dilated Intercellular Spaces in the Diagnosis and Pathophysiology of Heartburn	21
The Effects of Fermented Rice Drink With Lactiplantibacillus plantarum JSA22 in Overweight Irritable Bowel Syndrome Patients: A Randomized, Double-blind, Placebo-controlled Study	19
Distinct Effects of Non-absorbed Agents Rifaximin and Berberine on the Microbiota-Gut-Brain Axis in Dysbiosis-induced Visceral Hypersensitivity in Rats	19
Pyloric Functional Lumen Imaging Probe Measurements Are Dependent on Balloon Position	18
On-demand Versus Continuous Maintenance Treatment of Gastroesophageal Reflux Disease With Proton Pump Inhibitors: A Systematic Review and Meta-analysis	17
Clinical Trial: Efficacy of Mosapride Controlled-release and Nortriptyline in Patients With Functional Dyspepsia: A Multicenter, Double-placebo, Double-blinded, Randomized Controlled, Parallel Clinica	15
Refractory Gastroesophageal Reflux Disease: Diagnosis and Management	15
Randomized Multicenter Study to Evaluate the Efficacy and Safety of Fexuprazan According to the Timing of Dosing in Patients With Erosive Esophagitis	15
Overlap Between Constipation and Gastroesophageal Reflux Disease in Japan: Results From an Internet Survey	15
Exploring Diagnostic Challenges at the Intersection of Eating Disorders and Functional Dyspepsia: Implications for Rome V	14
Impact of Enhanced Dietary Education Program on Gastrointestinal Symptoms in Patients With Functional Gastrointestinal Disorders: A Multicenter Prospective Pilot Study	14
Influence of Menthol Infusion on Esophageal Peristalsis in Patients With Ineffective Esophageal Motility	14

Erratum	14
Heart Rate Variability and Somatization in Adolescents With Irritable Bowel Syndrome	13
A Randomized, Double-blinded, Placebo-controlled Study to Evaluate the Efficacy and Safety of DA-9701 (Motilitone) in Patients With Constipation-type Irritable Bowel Syndrome and Functional Dyspepsia	13
Gastric Myoelectrical Activity Subtypes in Functional Dyspepsia and Gastroparesis	13
Infantile Colic and the Subsequent Development of the Irritable Bowel Syndrome	13
Autonomic Dysfunction and Somatization in Young Patients With Irritable Bowel Syndrome and Mitral Valve Prolapse Syndrome	13
A Potential Role of Cholinergic Dysfunction on Impaired Colon Motility in Experimental Intestinal Chagas Disease	13
Clinical Implications of the Gastroesophageal Reflux Disease Questionnaire and Reflux Symptom Index in Patients With Suspected Laryngopharyngeal Reflux Symptoms	13
Multiple Sclerosis Is Associated With Achalasia and Diffuse Esophageal Spasm	12
Implementing a Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Diet in Asia: Addressing Cultural, Clinical and Practical Challenges	12
Exploring the Atypical Allergy Spectrum in Disorders of Gut-Brain Interactions: From Food to Aeroallergens	12
Superimposed Non-acid Reflux Event: An Example of When It May Be Important to Revisit the Impedance Analysis Guidelines	12
How to Implement the 3-Phase FODMAP Diet Into Gastroenterological Practice	12
Efficacy of acotiamide on postprandial distress syndrome and epigastric pain syndrome depending on the estimated gastric acid secretion level	11
Estimating Probability for Esophageal Obstruction: A Diagnostic Decision Support Tool Applying Machine Learning to Functional Lumen Imaging Probe Panometry	11
The Value of 3-Dimensional Anorectal Manometry in the Evaluation of Obstetric Anal Sphincter Injuries	11
Differences in Prevalence and Psychosocial Characteristics of Irritable Bowel Syndrome According to Rome III and Rome IV Criteria in Medical and Nursing Students	11
Phrenic Ampulla Emptying Dysfunction in Patients with Esophageal Symptoms	11
Diagnostic Criteria and Symptom Profiles in Adult Idiopathic Gastroparesis: A Systematic Review	11
Multiple Rapid Swallows: What Is the Optimal Protocol for Evaluation of Esophageal Contraction Reserve?	11
Small Intestinal Bacterial Overgrowth Complicating Gastrointestinal Manifestations of Systemic Sclerosis: A Systematic Review and Meta-analysis	10
Bile Acid and Gut Microbiota in Irritable Bowel Syndrome	10
Assessing Treatment Outcomes in Achalasia Using 4-Dimensional High-resolution Impedance Manometry	10
Reflux-related Extraesophageal Symptoms Until Proven Otherwise: A Direct Measurement of Abnormal Proximal Exposure Based on Hypopharyngeal Multichannel Intraluminal Impedance as a Reliable Indicator f	9
The Stressed Gut: Region-specific Immune and Neuroplasticity Changes in Response to Chronic Psychosocial Stress	9
Predicting Responsiveness to Biofeedback Therapy Using High-resolution Anorectal Manometry With Integrated Pressurized Volume	9
Risk Factors for Self-reported Irritable Bowel Syndrome With Prior Psychiatric Disorder: The Lifelines Cohort Study	9
A Higher Manometric Esophageal Length to Height Ratio in Achalasia Explains the Lower Prevalence of Hiatal Hernia	9
Factors Associated With the Prevalence of Irritable Bowel Syndrome: The Miyagi Part of the Tohoku Medical Megabank Project Community-based Cohort Study	9
Comparison of Fexuprazan and Esomeprazole for the Control of Nocturnal Gastroesophageal Reflux Symptoms: A Randomized, Crossover Study	9
Effect of Buspirone on Upper Gastrointestinal Disorders of Gut–Brain Interaction: A Systematic Review and Meta-analysis	9
Constipation in Patients With Chronic Kidney Disease	8
Baseline Impedance via Manometry Predicts Pathological Mean Nocturnal Baseline Impedance in Isolated Laryngopharyngeal Reflux Symptoms	8
The Esophageal Response to Distension on Functional Lumen Imaging Probe Panometry Is Minimally Changed by Conscious Sedation in Healthy Asymptomatic Subjects	8
Safety and Efficacy of Elobixibat, an Ileal Bile Acid Transporter Inhibitor, in Elderly Patients With Chronic Idiopathic Constipation According to Administration Time: Interim Analysis of Post-marketi	8
Disorders of Gut-Brain Interaction in Children With Down Syndrome	8
Functional Neuroimaging in Irritable Bowel Syndrome: A Systematic Review Highlights Common Brain Alterations With Functional Movement Disorders	8
From Morphology to Motion: Cine-magnetic Resonance Imaging in the Functional Assessment of Pseudo-obstruction	8
Effectiveness of Abdominal Massage Versus Kinesio Taping in Women With Chronic Constipation: A Randomized Controlled Trial	8
2022 Seoul Consensus on Clinical Practice Guidelines for Functional Constipation	8
The Implications of Mucosal Integrity and Microinflammation in the Pathogenesis of Gastroesophageal Reflux Disease	8
Association Between Psychological Burden and Unexplained High Upper Esophageal Sphincter Basal Pressure	8
An Optogenetics-based Approach to Regulate Colonic Contractions by Modulating the Activity of the Interstitial Cells of Cajal in Mice	8
A Systematic Review of the Development and Psychometric Properties of Constipation-Related Patient-Reported Outcome Measures: Opportunities for Digital Health	8
Diet, Physical Activity, and Chronic Constipation: Unveiling the Combined Effects for Better Treatment Strategies	7
Length of the Barrett’s Esophagus Is Proportional to the Abnormality of Esophageal Motility and Anti-reflux Barrier	7
Mean Nocturnal Baseline Impedance and Post-reflux Swallow-induced Peristaltic Wave Index Could Identify Gastroesophageal Reflux Disease but pH-Impedance Metrics Alone Might Not Correlate With Proton P	7
Retrograde Cricopharyngeus Dysfunction: Inability of Belch Due to Upper Esophageal Sphincter Relaxation Failure	7
Type of Rectal Barostat Protocol Affects Classification of Hypersensitivity and Prediction of Symptom Severity in Irritable Bowel Syndrome	7
Characteristics and Risk Factors of Functional Dyspepsia Fulfilling the Rome IV Criteria Overlapping With Gastroesophageal Reflux Disease, Irritable Bowel Syndrome, and Functional Constipation in Sout	7

Roles of Cytokines in Pathological and Physiological Gastroesophageal Reflux Exposure	7
Improving Clinician-Patient Communication Alleviates Stigma in Patients With Functional Dyspepsia Receiving Antidepressant Treatment	7
Multimorbidity of Allergic Diseases Is Associated With Functional Gastrointestinal Disorders in a Young Japanese Population	7
Editing Multichannel Intraluminal Impedance-pH Tracings to Reduce Non-reflux-related Esophageal Acidification	7