Journal of Advanced Research

Article	Citations
Value of ascitic fluid lipids in the differentiation between cirrhotic and malignant ascites	378
Not only the top: Type I topoisomerases function in multiple tissues and organs development in plants	285
NRIR promotes immune escape in hepatocellular cancer by regulating IFNγ-induced PD-L1 expression	277
STING-driven mitochondrial metabolism reverses cisplatin resistance via MDH2 desuccinylation in non-small cell lung cancer	263
Muscone promotes remyelination and alleviates Parkinson’s disease by targeting FKBP5 in MPTP-induced mouse model	263
Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries	212
Theoretical calculation-experimental collaborative design of integrated coating for degradation regulation and diagnosis-treatment of magnesium alloy for cerebrovascular stents	189
The therapeutic value of “Bile Transfer” for complications of acute pancreatitis: A retrospective clinical study	169
Escherichia coli expressing the kpsM gene exacerbates drug-induced liver injury through up-regulating α1,2-fucosyltransferase and disturbing the host taurine metabolism—from animal models and clinical	167
CHMP4C promotes pancreatic cancer progression by inhibiting necroptosis via the RIPK1/RIPK3/MLKL pathway	158
Long noncoding RNA AC007637.1 inhibits tumorigenesis by regulating the Trim25/PCNA axis in colorectal cancer	153
A multi-omics approach reveals that lotus root polysaccharide iron ameliorates iron deficiency-induced testicular damage by activating PPARγ to promote steroid hormone synthesis	150
Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial growth factor receptor 2 pathway in inflammatory bowel disease	148
Effect of platelet-rich plasma in refractory vitiligo by promoting the differentiation of dermal melanocyte progenitors via IGFBP-2/RhoA/YAP pathway	146
Defect passivation and transformation of Ti3C2Tx MXene hollow microsphere for superior electrochemical performance and sodium-ions storage	145
Autoimmune responses to myelin-associated proteins as diagnostic and prognostic biomarkers of relapsing-remitting multiple sclerosis: Associations with human herpesvirus-6 and Epstein-Barr virus react	141
Lipidomics identified novel cholesterol-independent predictors for risk of incident coronary heart disease: Mediation of risk from diabetes and aggravation of risk by ambient air pollution	136
Development and validation of dynamic clinical subphenotypes for acute pancreatitis using hematocrit and blood urea nitrogen trajectories in intensive care unit: a multicenter retrospective cohort stu	123
Synergistic effect of cold gas plasma and experimental drug exposure exhibits skin cancer toxicity in vitro and in vivo	123
The transcription factor PbbHLH164 is destabilized by PbRAD23C/D.1 and mediates ethylene biosynthesis during pear fruit ripening	122
Rural-urban disparities in cardiovascular and other competing risk of death among cancer patients	121
High throughput screening identifies sanguinarine chloride as a multi-faceted therapeutic agent for PRCC-TFE3 rRCC by targeting lactylation-driven VEGFB-VEGFR2 signaling and PMN-MDSC infiltration	121
Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx	121
Engineered natural extracellular matrix platform for modelling skin diseases and identifying therapeutic targets	119
H3K27me3-mediated chromatin remodeling governs salt tolerance in cotton via Na+/K+ homeostasis modulation	119

Genomic loci associated with leaf abscission contribute to machine picking and environmental adaptability in upland cotton (Gossypium hirsutum L.)	117
Lactobacillus johnsonii-derived extracellular vesicles carrying GAPDH protect against ulcerative colitis through modulating macrophage polarization	115
Pomegranate peel extract alleviates diabetic retinopathy by suppressing the PI3K/AKT/HIF-1α/VEGF pathway and gut microbiota modulation	115
A micropillar array-based microfluidic chip for label-free separation of circulating tumor cells: The best micropillar geometry?	114
SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization	112
Development and clinical validation of a novel protein biomarkers-based algorithm for risk prediction and diagnosis of advanced liver fibrosis: a multi-centre study	110
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD	106
Optimizing therapeutic efficacy of antifungal peptides via strategic terminal amino acid modification	105
Transcriptomic and metabolomic profiles reveal the functions of IGF-1 c.258 A > G synonymous mutation in milk fat content	105
Gossypium purpurascens genome provides insight into the origin and domestication of upland cotton	103
Rab32-based vesicles coordinate mitochondria and actin for spindle migration and organelle rearrangement in oocyte meiosis	102
Interactive canopy nitrogen and water additions delay phenology in a warm-temperate forest	100
Unraveling the nexus in the neuro-neoplastic progression of colorectal cancer: Potential role of β2-adrenergic receptor (β2-AR)	99
Insights into modifiable risk factors of erectile dysfunction, a wide-angled Mendelian Randomization study	99
Four distinct pathways involved in a “tug-of-war” lead to the non-linear nature of phenolic chemistry during lactic acid fermentation of fruits and vegetables	98
RNA methylation modifications in neurodegenerative diseases: Focus on their enzyme system	97
Study of benign prostatic hyperplasia and androgen pathway manipulation on lung cancer survivals	94
The NLRP3 molecule influences the therapeutic effects of mesenchymal stem cells through Glut1-mediated energy metabolic reprogramming	93
Dynamic bidirectional diffusion-controlled multi-enzyme system for one-pot viral detection	93
Advancements in bone organoids: perspectives on construction methodologies and application strategies	93
Population genomics analyses reveal the role of hybridization in the rapid invasion of fall armyworm	93
Injectable Chito-oligosaccharide-hyaluronic acid hydrogels with Fe3+/AMP nano-enzyme promote ROS scavenging and immunomodulation for myocardial infarction repair	90
OsCPK9-mediated Thr105 phosphorylation activates OsCATC to enhance drought tolerance in rice	84
c-Myc-PANK3-EMT axis regulates the structure and function of intestinal barrier in ulcerative colitis	84
Adaptive bilirubin nanoscavenger alleviates pulmonary oxidative stress and inflammation for acute lung injury therapy	84
Kaempferol alleviates myocardial ischemia injury by reducing oxidative stress via the HDAC3-mediated Nrf2 signaling pathway	84
LPCAT3 deficiency Drives phospholipid remodeling and mitochondrial oxidative dysfunction to accelerate MASH-HCC development	83
Targeting fibrillin-1 disrupts the fibrogenic niche formation and ameliorates kidney fibrosis	83
Clostridium butyricum and its metabolites regulate macrophage polarization through miR-146a to antagonize gouty arthritis	82
Clinical evaluation of cell-free and cellular metagenomic next-generation sequencing of infected body fluids	81
Applications of single-cell analysis in immunotherapy for lung cancer: Current progress, new challenges and expectations	81
Redox status of the plant cell determines epigenetic modifications under abiotic stress conditions and during developmental processes	80
Association between dietary amino acid intake and the risk of metabolic dysfunction-associated steatotic liver disease	80
Forsythiaside A alleviates acute lung injury by inhibiting inflammation and epithelial barrier damages in lung and colon through PPAR-γ/RXR-α complex	79
Functions of FGF21 and its role in cardiac hypertrophy	79
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism	79
Unraveling competitive protein interactions: A critical step toward improved production and therapeutics	79
Digital techniques and trends for seed phenotyping using optical sensors	78
TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway	78
Tissue-resolved molecular landscape reveals hepatic regulatory networks and metabolic mediators underlying feed efficiency in chickens	78
Lactation duration and the risk of type 2 diabetes mellitus in parous women: A perspective on socioeconomic status disparity	76
A “DUBTAC” targeting GLUL deubiquitination promotes BMSC osteogenic differentiation and implant osseointegration in type 2 diabetes	74
Full dimensional dynamic 3D convolution and point cloud in pulmonary nodule detection	74
Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells	74
Computational glycosyltransferases masked deoxynivalenol toxicity and halted FHB spread in wheat grains	73
The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology	73
An increase in DNA methylation contributes to anthocyanin biosynthesis in the pericarp as litchi (Litchi chinensis Sonn.) fruit ripens	72
Editorial Board	72
Title Page	72
Periventricular gradient of normal-appearing white matter in normal aging and multiple neurological diseases	71

Editorial Board	71
CD34+CLDN5+ tumor associated senescent endothelial cells through IGF2-IGF2R signaling increased cholangiocellular phenotype in hepatocellular carcinoma	70
Extracellular matrix-inspired multi-morphology microspheres harness osteogenic-prone stem cells to recruit and reprogram adjacent stem cells for synergistic bone regeneration	70
SAMD4A inhibits abdominal aortic aneurysm development and VSMC phenotypic transformation through targeting KDM2B	69
Rationally designed BCR-ABL kinase inhibitors for improved leukemia treatment via covalent and pro-/dual-drug targeting strategies	68
HIF-1α inhibition by MO-2097, a novel chiral-free benzofuran targeting hnRNPA2B1	68
METTL4 enhances GLI1 translation through m6Am modification to promote tumor progression as a therapeutic target for hepatocellular carcinoma	67
Ursolic acid reduces Aβ-driven aggression via Gab1-mediated autophagy and dorsal hippocampal circuit modulation in Alzheimer’s disease	66
Dietary EGCG reshapes metabolic-epigenetic interplay to induce transgenerational host defense	66
Noninvasive detection and differentiation of gastric malignancy using cell-free DNA biomarkers	65
SLC7A11 as a therapeutic target to attenuate phthalates-driven testosterone level decline in mice	64
Design of highly leaf-adhesive and anti-UV herbicide nanoformulation for enhanced herbicidal activity	64
Integrated multi-omics analysis to elucidate the genetic basis of seed traits in cotton	63
The role of cGAS-STING signaling pathway in ferroptosis	63
Active polymerization regions of G and S monolignols show different temporal and spatial change patterns in the multicellular space during lignification and its inhibition of the fruit flesh	63
Metabolic interactions drive microbial community succession and functional expression of Nongxiangxing (Strong-flavor) daqu	62
Piezo1 inhibition promoted MELK degradation and impeded influenza virus entry into host cells	62
Hierarchical double-layer microneedles accomplish multicenter skin regeneration in diabetic full-thickness wounds	62
The immune regulation and signaling transduction of FAM134B-mediated endoplasmic reticulum-phagy in ferroptosis of dendritic cells after sepsis	62
Aroma compounds with enhanced sweet perception in tea infusions: Screening, characterization, and sweetening mechanism	62
Restoring mitochondrial lipid homeostasis with arachidonic acid supplementation to alleviate cognitive impairment in schizophrenia patients	61
Chrono-nutrition in precision nutrition: Integrating chronotype into personalized dietary interventions	61
Early gut microbiota intervention in premature infants: Application perspectives	61
S-sulfhydration: Novel insights into the antioxidant and antiinflammation in age-related diseases	61
Bioengineered JMJD3-PROTAC targeted epigenetic immunotherapy strategy for diabetic periodontitis	61
Bile acid and nonalcoholic steatohepatitis: Molecular insights and therapeutic targets	61
Comprehensive multi-omics analyses expose a precision therapy strategy that targets replication stress in hepatocellular carcinoma using WEE1 inhibition	60
The BET inhibitor JQ1 targets fat metabolism and counteracts obesity	59
Intracellular Fusobacterium nucleatum infection increases METTL3-mediated m6A methylation to promote the metastasis of esophageal squamous cell carcinoma	59
Snapin mediates neuronal PANoptosis after mild traumatic brain injury via H2S-dependent S-sulfhydration of CTSD	59
Advanced colorectal neoplasia and colorectal cancer in metabolic dysfunction-associated steatotic liver disease	58
NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner	58
Synthesis of scarless circular RNAs expressing long-acting GLP-1RAs for type 2 diabetes therapy	58
Spatial-temporal lipidomics reveals dysregulated lipid metabolism in mouse brain during Alzheimer’s disease progression	58
Enhanced tuberculosis control via leveraging dendritic cell-mediated Th1 responses in preventive and immunotherapeutic vaccine strategies	58
Soybean nodulation shapes the rhizosphere microbiome to increase rapeseed yield	58
Histone H4 lysine 12 lactylation-driven ZIP14 expression is involved in electroacupuncture therapy against cerebral ischemia/reperfusion injury in mice	58
Epigallocatechin gallate prevents and alleviates type 2 diabetes mellitus (T2DM) through gut microbiota and multi-organ interactions in Wistar healthy rats and GK T2DM rats	57
Strain specificity of lactobacilli with promoted colonization by galactooligosaccharides administration in protecting intestinal barriers during Salmonella infection	57
Consistency and reproducibility of large panel next-generation sequencing: Multi-laboratory assessment of somatic mutation detection on reference materials with mismatch repair and proofreading defici	57
Kynurenine acts as a signaling molecule to attenuate pulmonary fibrosis by enhancing the AHR-PTEN axis	56
Human serum albumin-derived biosensor for visualizing copper(II) and hydrogen sulfide interactions in cancer cells	55
Recent progress in renewable energy based-desalination in the Middle East and North Africa MENA region	55
Dynamic regulation and targeted interventions of macrophages in ischemia–reperfusion injury	55
CDK4/6 inhibitor PD-0332991 suppresses hepatocarcinogenesis by inducing senescence of hepatic tumor-initiating cells	55
Dose-effect of polystyrene microplastics on digestive toxicity in chickens (Gallus gallus): Multi-omics reveals critical role of gut-liver axis	55
FGF21-FGFR1 signaling protects against cardiac hypertrophy by regulating PINK1-mediated mitophagy pathway	54
Ultrafast in situ formation of antibiotic-free injectable hydrogel dressings with innate antibacterial activity and autolysis capacity for wound healing	54
Maxillary palp odorant-binding proteins as key mediators of bitter taste and molecular targets for cockroach control	54
Targeting CIRP and IL-6R-mediated microglial inflammation to improve outcomes in intracerebral hemorrhage	54
Astragaloside IV alleviates septic myocardial injury through DUSP1-Prohibitin 2 mediated mitochondrial quality control and ER-autophagy	54
NRXN3 regulates pyroptosis in intrahepatic cholangiocarcinoma via mediating the phospho-dependent ubiquitination and degradation of caspase-3	54
TEMPORARY REMOVAL: PDZK1 disassembles HER2-HSP90 complexes to promote ubiquitin-mediated HER2 degradation and overcome therapy resistance	54
Small nucleolar RNAs and SNHGs in the intestinal mucosal barrier: Emerging insights and current roles	53
Shikonin nasal spray film preparation promoted the repair of nasal mucosal injury by the interaction of shikonin with interleukin-6	53
Temporal variability of urinary microcystin-LR concentrations in healthy adult men: Recommendations for sampling strategy	53
Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome	53
Editorial Board	52
Editorial Board	52
Modulating GRP75 to restore calcium homeostasis: a novel neuroprotective strategy of CRSE6# in Parkinson’s disease models	52
Synthetic tunable promoters for flexible control of multi-gene expression in mammalian cells	52
Construction of musculoskeletal quantitative model based on deep learning and study of musculoskeletal relationship in patients with osteoporosis	52
Genotype-driven variations in lncRNA expression underlie predisposition to high-grade serous ovarian cancer	52
Anti-inflammatory therapy in hepatic encephalopathy: A systematic review and meta-analysis	52
Nicotinamide riboside alleviates ionizing radiation-induced intestinal senescence by alleviating oxidative damage and regulating intestinal metabolism	52
Unraveling the anti-corrosion mechanisms of a novel hydrazone derivative on steel in contaminated concrete pore solutions: An integrated study	52
The applications of deep learning algorithms on in silico druggable proteins identification	51
Calcium influx: An essential process by which α-Synuclein regulates morphology of erythrocytes	51
Cadmium accumulation regulated by a rice heavy-metal importer is harmful for host plant and leaf bacteria	51
OTUD7B attenuates renal fibrosis by regulating PRDX1 protein stability	51
Ginsenoside Rb2 inhibits p300-mediated SF3A2 acetylation at lysine 10 to promote Fscn1 alternative splicing against myocardial ischemic/reperfusion injury	51
Biomechanical research using advanced micro-nano devices: In-Vitro cell Characterization focus	51
Aging induces sarcopenia by disrupting the crosstalk between the skeletal muscle microenvironment and myofibers	50
Multi-omics reveals an ecdysone-activated Eip75B-FABP signaling axis coordinating nutrient metabolism for development in Hermetia illucens	50
The miR408a-BBP-LAC3/CSD1 module regulates anthocyanin biosynthesis mediated by crosstalk between copper homeostasis and ROS homeostasis during light induction in Malus plants	50
Alarm: Retracted articles on cancer imaging are not only continuously cited by publications but also used by ChatGPT to answer questions	50
DAMP signaling networks: from receptors to diverse pathophysiological functions	49
Glycyrrhiza, a commonly used medicinal herb: Review of species classification, pharmacology, active ingredient biosynthesis, and synthetic biology	49
A novel TGR5 agonist Sauchinone ameliorates IMQ induced murine psoriasis by regulating macrophage polarization	48
YAP/TAZ, beta-catenin, and TGFb pathway activation in medical plasma-induced wound healing in diabetic mice	48

Piezo1 activation accelerates osteoarthritis progression and the targeted therapy effect of artemisinin	48
Efficient chemo-immunotherapy leveraging minimalist electrostatic complex nanoparticle as “in situ” vaccine integrated tumor ICD and immunoagonist	48
Endothelial NMMHC IIA dissociation from PAR1 activates the CREB3/ARF4 signaling in thrombin-mediated intracerebral hemorrhage	48
Integrating research on plant responses to light limitation across scales	48
A natural carotenoid crocin exerts antidepressant action by promoting adult hippocampal neurogenesis through Wnt/β-catenin signaling	47
Global, regional, and national childhood cancer burden, 1990–2019: An analysis based on the Global Burden of Disease Study 2019	47
Convergent and divergent transcriptional reprogramming of motor and sensory neurons underlying response to peripheral nerve injury	47
Antifouling applications and fabrications of biomimetic micro-structured surfaces: A review	47
Beaver behavior optimizer: A novel metaheuristic algorithm for solar PV parameter identification and engineering problems	46
Brain-targeted autoimmunity is strongly associated with Long COVID and its chronic fatigue syndrome as well as its affective symptoms	46
Mitochondrial dysfunction drives ZBP1-mediated PANoptosis to increase the susceptibility of heart failure with preserved ejection fraction-associated atrial fibrillation	46
Blockchain and PUF-based secure key establishment protocol for cross-domain digital twins in industrial Internet of Things architecture	46
Recent research progress and clinical status of immunotherapy for colorectal cancer	46
Insomnia: the gut microbiome connection, prospects for probiotic and postbiotic therapies, and future directions	46
Berberine suppresses colorectal cancer progression by inducing ferroptosis-mediated energy metabolism disorders	46
Alanine metabolism mediates energy allocation of the brown planthopper to adapt to resistant rice	45
Targeting FBXO48 with BC1618 promotes axon regeneration and alleviates symptoms of Parkinson’s disease	45
Sympathetic innervation induces exosomal miR-125 transfer from osteoarthritic chondrocytes, disrupting subchondral bone homeostasis and aggravating cartilage damage in aging mice	45
Challenges and advances in the management of inflammation in atherosclerosis	44
Ginsenoside Rh1 ameliorates polystyrene nanoplastics-caused vascular injury by regulating HSP70 to suppress endoplasmic reticulum stress and pyroptosis	44
Alveolar macrophage-derived TGF-β promotes acute lung injury recovery by regulating inflammatory monocyte-derived macrophages	44
HMGB1/STAT3/p65 axis drives microglial activation and autophagy exert a crucial role in chronic Stress-Induced major depressive disorder	44
AI-enabled language models (LMs) to large language models (LLMs) and multimodal large language models (MLLMs) in drug discovery and development	44
Mass spectrometry unveils heat-induced changes in yolk oxylipins and key lipid molecules during home cooking	44
Structure-based ligand design and discovery of novel tenuazonic acid derivatives with high herbicidal activity	44
Editorial Board	43
Armodafinil ameliorated fibromyalgia through modulating dopamine and neuroinflammation	43
Editorial Board	43
Graphdiyne as an emerging sensor platform: Principles, synthesis and application	43
Title Page	43
Corrigendum to “An updated review and recent advancements in carbon-based bioactive coatings for dental implant applications” [J. Adv. Res. 72 (2025) 265–286]	43
Genome variations reveal rapid adaptation to domestication and habitat changes in the brown algae Saccharina japonica	42
Eicosapentaenoic acid enhances intestinal stem cell-mediated colonic epithelial regeneration by activating the LSD1-WNT signaling pathway	42
Beet cyst nematode HsSNARE1 interacts with both AtSNAP2 and AtPR1 and promotes disease in Arabidopsis	42
Targeting acid ceramidase enhances antitumor immune response in colorectal cancer	42
Synergistic Antitumor Activity and Neuroprotective Effects of FGF1/FGFR Inhibition with Oxaliplatin Chemotherapy	42
Non-invasive and painless mid-infrared modulation increases collagen in human and mouse skin	42
Low-frequency magnetic field therapy for glioblastoma: Current advances, mechanisms, challenges and future perspectives	42
The urinary eccDNA landscape in prostate cancer reveals associations with genome instability and vital roles in cancer progression	41
Fibroblast-derived BMP5 promotes tendon adhesion by inducing bone marrow mesenchymal stromal cells to differentiate into myofibroblasts	41
Pachymic acid targets PDIA6 to delay mesenchymal stem cell senescence through the G6PD/STAT3 signaling axis and prevent senile osteoporosis	41
Essential function of Nr4a2 in subicular development and social novelty	41
A novel Synthetic phenotype association study approach reveals the landscape of association for genomic variants and phenotypes	41
The biomedical application of inorganic metal nanoparticles in aging and aging-associated diseases	41
Moscatilin inhibits vascular calcification by activating IL13RA2-dependent inhibition of STAT3 and attenuating the WNT3/β-catenin signalling pathway	41
Discovery of FBP1 as novel therapeutic target and asiatic acid-hydrogen sulfide donors accelerate diabetic wound healing	41
RNA-m5C regulatory atlas of human fetal tissues uncover the activities of Nsun2/Jarid2/Alyref axis	41
Design of a Haversian system-like gradient porous scaffold based on triply periodic minimal surfaces for promoting bone regeneration	40
Resuscitation of viable but nonculturable bacteria promoted by ATP-mediated NAD+ synthesis	40
Rational engineering of an antifreeze-based biomaterial with dual-enhanced ice-binding and delivery for high-efficiency cryopreservation	40
NCOA4-Mediated Ferritinophagy Induces Ferroptosis and Enriches Ferritin-Containing EVs via Ferritin Phase Separation to Promote Mechanical Ventilation-Induced Pulmonary Fibrosis	40
Marine n-3 fatty acids protect against renal function deterioration in diabetic patients by modulating lipoproteins and promoting cholesterol efflux	40
Bovine milk microbiota: Key players, origins, and potential contributions to early-life gut development	40
Illustrating the functional heterogeneity of M-MDSCs to predict sepsis outcomes	40
Insights of immune cell heterogeneity, tumor-initiated subtype transformation, drug resistance, treatment and detecting technologies in glioma microenvironment	40
Cigarette smoke-promoted increases in osteopontin expression attract mesenchymal stem cell recruitment and facilitate lung cancer metastasis	40
Nervonic acid triggered ovarian inflammation by inducing mitochondrial oxidative stress to activate NLRP3/ IL-1β pathway	39
Therapeutic potential of ELABELA in alleviating hereditary hypertrophic cardiomyopathy	39
Cisplatin and gemcitabine exert opposite effects on immunotherapy with PD-1 antibody in K-ras-driven cancer	39
Sex-specific proteomic signatures improve cardiovascular risk prediction for the general population without cardiovascular disease or diabetes	38
Vinculin mediates a dynamic signal flow underlying cardiac outflow tract development as revealed by single-cell and spatial transcriptomic analysis	38
Study of the sensitization mechanism of immunoassay based on DNA tetrahedron spatial mediation for detecting imidacloprid in vegetables	38
Targeting the muscle-brain axis to improve post-stroke cognition via the FNDC5/irisin/BDNF pathway	38
11-keto-β-boswellic acid and Z-guggulsterone suppress HMGB1/TLR4 pathway activity and modulate microglial polarization to remodel perineuronal nets after nerve injury	38
Ubiquitin proteasome system in cardiac fibrosis	37
Plasma proteomics identify novel biomarkers and dynamic patterns of biological aging	37
Antimicrobial activities of lavandulylated flavonoids in Sophora flavences against methicillin-resistant Staphylococcus aureus via membrane disruption	37
Connexin-43 is a promising target for lycopene preventing phthalate-induced spermatogenic disorders	37
Dimeric guaianolide sesquiterpenoids from the flowers of Chrysanthemum indicum ameliorate hepatic steatosis through mitigating SIRT1-mediated lipid accumulation and ferroptosis	37
IDD10-NAC079 transcription factor complex regulates sheath blight resistance by inhibiting ethylene signaling in rice	37
A female-biased odorant receptor tuned to the lepidopteran sex pheromone in parasitoid Microplitis mediator guiding habitat of host insects	37
A potential CO2 carrier to improve the utilization of HCO3– by plant-soil ecosystem for carbon sink enhancement	37
An ABC transporter-mediated transport and metabolism of the pesticide bentazone in rice (Oryza sativa L.)	37
Exercise-Induced Reduction of IGF1R Sumoylation Attenuates Neuroinflammation in APP/PS1 Transgenic Mice	37
Integrated stress response activation induced by usnic acid alleviates BCL-2 inhibitor ABT-199 resistance in acute myeloid leukemia	36
Osteoblast-derived CTGF contributes to detrimental bone-cartilage crosstalk via EGFR/ NF-κB signaling pathway in estrogen-deficiency-induced osteoarthritis	36
Exploring genetic diversity of wild and related tetraploid wheat species Triticum turgidum and Triticum timopheevii	36
Ginger exosome-like nanoparticle-derived miRNA therapeutics: A strategic inhibitor of intestinal inflammation	36
Kaempferol regulating macrophage foaming and atherosclerosis through Piezo1-mediated MAPK/NF-κB and Nrf2/HO-1 signaling pathway	36
Urinary Cell-Free DNA detection platform for bacterial cystitis diagnosis via spot-based machine learning	36
Arachidonic acid in aging: New roles for old players	35
Intelligent microfluidic device for multiplex detection and prompt warning of upper and lower respiratory tract infections	35
E3 ubiquitin ligase RNF128 attenuates colitis and colorectal tumorigenesis by triggering the degradation of IL-6 receptors	35
JAM-C prevents ocular fibrosis by suppressing the TAZ/KLF6 pathway	35
Tumour-specific delivery of ω-conotoxin MVIIA via engineered Salmonella for safe anticancer therapy	35
Transforming growth factor-β receptor 1: An intervention target for genetic poor cartilage quality induced by prenatal dexamethasone exposure	35
Procyanidin C1 inhibits tumor growth and metastasis in colon cancer via modulating miR-501-3p/HIGD1A axis	35
Integrated deep eutectic system enrichment and AI-assisted high-throughput visual detection for Hg2+ in environmental samples	35
Discovery of mannose as an alternative non-nutrient-deficient regulator of lipid accumulation in microalgae	35
New insights on mitochondrial heteroplasmy observed in ovarian diseases	35
Editorial Board	35
Review of research advances in the cerebral lymphatic system and neurological disorders	34
Role of capsaicin, circadian clock genes, and TRPV1 in colorectal carcinogenesis: Lessons and future directions	34
Roles of Msx2 in exogen control: modulating the stem cell niche during the transition from hair shedding to regeneration	34
Squalene epoxidase promotes paraquat-induced pulmonary toxicity through endoplasmic reticulum-mediated ferroptosis	34