Journal of Advanced Research

Article	Citations
Value of ascitic fluid lipids in the differentiation between cirrhotic and malignant ascites	361
Not only the top: Type I topoisomerases function in multiple tissues and organs development in plants	274
OsCPK9-mediated Thr105 phosphorylation activates OsCATC to enhance drought tolerance in rice	264
RNA methylation modifications in neurodegenerative diseases: Focus on their enzyme system	240
NRIR promotes immune escape in hepatocellular cancer by regulating IFNγ-induced PD-L1 expression	231
Pomegranate peel extract alleviates diabetic retinopathy by suppressing the PI3K/AKT/HIF-1α/VEGF pathway and gut microbiota modulation	195
c-Myc-PANK3-EMT axis regulates the structure and function of intestinal barrier in ulcerative colitis	179
Gossypium purpurascens genome provides insight into the origin and domestication of upland cotton	153
The transcription factor PbbHLH164 is destabilized by PbRAD23C/D.1 and mediates ethylene biosynthesis during pear fruit ripening	151
Unraveling competitive protein interactions: A critical step toward improved production and therapeutics	141
Rural-urban disparities in cardiovascular and other competing risk of death among cancer patients	140
Transcriptomic and metabolomic profiles reveal the functions of IGF-1 c.258 A > G synonymous mutation in milk fat content	138
A micropillar array-based microfluidic chip for label-free separation of circulating tumor cells: The best micropillar geometry?	138
LPCAT3 deficiency Drives phospholipid remodeling and mitochondrial oxidative dysfunction to accelerate MASH-HCC development	133
Development and validation of dynamic clinical subphenotypes for acute pancreatitis using hematocrit and blood urea nitrogen trajectories in intensive care unit: a multicenter retrospective cohort stu	131
High throughput screening identifies sanguinarine chloride as a multi-faceted therapeutic agent for PRCC-TFE3 rRCC by targeting lactylation-driven VEGFB-VEGFR2 signaling and PMN-MDSC infiltration	130
Clinical evaluation of cell-free and cellular metagenomic next-generation sequencing of infected body fluids	130
Tissue-resolved molecular landscape reveals hepatic regulatory networks and metabolic mediators underlying feed efficiency in chickens	125
Muscone promotes remyelination and alleviates Parkinson’s disease by targeting FKBP5 in MPTP-induced mouse model	118
STING-driven mitochondrial metabolism reverses cisplatin resistance via MDH2 desuccinylation in non-small cell lung cancer	118
H3K27me3-mediated chromatin remodeling governs salt tolerance in cotton via Na+/K+ homeostasis modulation	117
TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway	113
Clostridium butyricum and its metabolites regulate macrophage polarization through miR-146a to antagonize gouty arthritis	113
Theoretical calculation-experimental collaborative design of integrated coating for degradation regulation and diagnosis-treatment of magnesium alloy for cerebrovascular stents	110
Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries	110

Advancements in bone organoids: perspectives on construction methodologies and application strategies	110
Rab32-based vesicles coordinate mitochondria and actin for spindle migration and organelle rearrangement in oocyte meiosis	110
Association between dietary amino acid intake and the risk of metabolic dysfunction-associated steatotic liver disease	106
Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial growth factor receptor 2 pathway in inflammatory bowel disease	105
Applications of single-cell analysis in immunotherapy for lung cancer: Current progress, new challenges and expectations	101
The therapeutic value of “Bile Transfer” for complications of acute pancreatitis: A retrospective clinical study	100
Adaptive bilirubin nanoscavenger alleviates pulmonary oxidative stress and inflammation for acute lung injury therapy	97
Escherichia coli expressing the kpsM gene exacerbates drug-induced liver injury through up-regulating α1,2-fucosyltransferase and disturbing the host taurine metabolism—from animal models and clinical	97
SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization	97
Defect passivation and transformation of Ti3C2Tx MXene hollow microsphere for superior electrochemical performance and sodium-ions storage	97
CHMP4C promotes pancreatic cancer progression by inhibiting necroptosis via the RIPK1/RIPK3/MLKL pathway	94
Insights into modifiable risk factors of erectile dysfunction, a wide-angled Mendelian Randomization study	92
Long noncoding RNA AC007637.1 inhibits tumorigenesis by regulating the Trim25/PCNA axis in colorectal cancer	91
Autoimmune responses to myelin-associated proteins as diagnostic and prognostic biomarkers of relapsing-remitting multiple sclerosis: Associations with human herpesvirus-6 and Epstein-Barr virus react	90
A multi-omics approach reveals that lotus root polysaccharide iron ameliorates iron deficiency-induced testicular damage by activating PPARγ to promote steroid hormone synthesis	90
Engineered natural extracellular matrix platform for modelling skin diseases and therapeutic targets discovery	90
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD	88
Synergistic effect of cold gas plasma and experimental drug exposure exhibits skin cancer toxicity in vitro and in vivo	86
Population genomics analyses reveal the role of hybridization in the rapid invasion of fall armyworm	83
Unraveling the nexus in the neuro-neoplastic progression of colorectal cancer: Potential role of β2-adrenergic receptor (β2-AR)	83
Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx	82
Digital techniques and trends for seed phenotyping using optical sensors	80
Lipidomics identified novel cholesterol-independent predictors for risk of incident coronary heart disease: Mediation of risk from diabetes and aggravation of risk by ambient air pollution	79
Redox status of the plant cell determines epigenetic modifications under abiotic stress conditions and during developmental processes	79
Forsythiaside A alleviates acute lung injury by inhibiting inflammation and epithelial barrier damages in lung and colon through PPAR-γ/RXR-α complex	78
Development and clinical validation of a novel protein biomarkers-based algorithm for risk prediction and diagnosis of advanced liver fibrosis: a multi-centre study	78
Four distinct pathways involved in a “tug-of-war” lead to the non-linear nature of phenolic chemistry during lactic acid fermentation of fruits and vegetables	77
The NLRP3 molecule influences the therapeutic effects of mesenchymal stem cells through Glut1-mediated energy metabolic reprogramming	77
Genomic loci associated with leaf abscission contribute to machine picking and environmental adaptability in upland cotton (Gossypium hirsutum L.)	77
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism	76
Kaempferol alleviates myocardial ischemia injury by reducing oxidative stress via the HDAC3-mediated Nrf2 signaling pathway	76
Functions of FGF21 and its role in cardiac hypertrophy	76
Lactobacillus johnsonii-derived extracellular vesicles carrying GAPDH protect against ulcerative colitis through modulating macrophage polarization	75
Effect of platelet-rich plasma in refractory vitiligo by promoting the differentiation of dermal melanocyte progenitors via IGFBP-2/RhoA/YAP pathway	75
Optimizing therapeutic efficacy of antifungal peptides via strategic terminal amino acid modification	75
Lactation duration and the risk of type 2 diabetes mellitus in parous women: A perspective on socioeconomic status disparity	74
S-sulfhydration: Novel insights into the antioxidant and antiinflammation in age-related diseases	74
Full dimensional dynamic 3D convolution and point cloud in pulmonary nodule detection	74
A “DUBTAC” targeting GLUL deubiquitination promotes BMSC osteogenic differentiation and implant osseointegration in type 2 diabetes	74
Strain specificity of lactobacilli with promoted colonization by galactooligosaccharides administration in protecting intestinal barriers during Salmonella infection	73
The BET inhibitor JQ1 targets fat metabolism and counteracts obesity	71
Consistency and reproducibility of large panel next-generation sequencing: Multi-laboratory assessment of somatic mutation detection on reference materials with mismatch repair and proofreading defici	70
The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology	70
Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells	70
Computational glycosyltransferases masked deoxynivalenol toxicity and halted FHB spread in wheat grains	69
Enhanced tuberculosis control via leveraging dendritic cell-mediated Th1 responses in preventive and immunotherapeutic vaccine strategies	69
The immune regulation and signaling transduction of FAM134B-mediated endoplasmic reticulum-phagy in ferroptosis of dendritic cells after sepsis	68
Early gut microbiota intervention in premature infants: Application perspectives	67
An increase in DNA methylation contributes to anthocyanin biosynthesis in the pericarp as litchi (Litchi chinensis Sonn.) fruit ripens	65
Hierarchical double-layer microneedles accomplish multicenter skin regeneration in diabetic full-thickness wounds	64

Title Page	64
The role of cGAS-STING signaling pathway in ferroptosis	64
Aroma compounds with enhanced sweet perception in tea infusions: Screening, characterization, and sweetening mechanism	64
NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner	64
Editorial Board	63
Editorial Board	63
Active polymerization regions of G and S monolignols show different temporal and spatial change patterns in the multicellular space during lignification and its inhibition of the fruit flesh	63
Spatial-temporal lipidomics reveals dysregulated lipid metabolism in mouse brain during Alzheimer’s disease progression	62
SLC7A11 as a therapeutic target to attenuate phthalates-driven testosterone level decline in mice	61
Kynurenine acts as a signaling molecule to attenuate pulmonary fibrosis by enhancing the AHR-PTEN axis	61
Dynamic regulation and targeted interventions of macrophages in ischemia–reperfusion injury	61
Integrated multi-omics analysis to elucidate the genetic basis of seed traits in cotton	60
Synthesis of scarless circular RNAs expressing long-acting GLP-1RAs for type 2 diabetes therapy	59
Recent progress in renewable energy based-desalination in the Middle East and North Africa MENA region	59
Ultrafast in situ formation of antibiotic-free injectable hydrogel dressings with innate antibacterial activity and autolysis capacity for wound healing	58
Transcription factor Meis1 act as a new regulator of ischemic arrhythmias in mice	58
Periventricular gradient of normal-appearing white matter in normal aging and multiple neurological diseases	57
CDK4/6 inhibitor PD-0332991 suppresses hepatocarcinogenesis by inducing senescence of hepatic tumor-initiating cells	56
Extracellular matrix-inspired multi-morphology microspheres harness osteogenic-prone stem cells to recruit and reprogram adjacent stem cells for synergistic bone regeneration	56
Epigallocatechin gallate prevents and alleviates type 2 diabetes mellitus (T2DM) through gut microbiota and multi-organ interactions in Wistar healthy rats and GK T2DM rats	56
Chrono-nutrition in precision nutrition: Integrating chronotype into personalized dietary interventions	56
Ursolic acid reduces Aβ-driven aggression via Gab1-mediated autophagy and dorsal hippocampal circuit modulation in Alzheimer’s disease	55
METTL4 enhances GLI1 translation through m6Am modification to promote tumor progression as a therapeutic target for hepatocellular carcinoma	55
Astragaloside IV alleviates septic myocardial injury through DUSP1-Prohibitin 2 mediated mitochondrial quality control and ER-autophagy	55
Dietary EGCG reshapes metabolic-epigenetic interplay to induce transgenerational host defense	55
Comprehensive multi-omics analyses expose a precision therapy strategy that targets replication stress in hepatocellular carcinoma using WEE1 inhibition	55
Bile acid and nonalcoholic steatohepatitis: Molecular insights and therapeutic targets	54
Soybean nodulation shapes the rhizosphere microbiome to increase rapeseed yield	54
Histone H4 lysine 12 lactylation-driven ZIP14 expression is involved in electroacupuncture therapy against cerebral ischemia/reperfusion injury in mice	54
Noninvasive detection and differentiation of gastric malignancy using cell-free DNA biomarkers	54
Design of highly leaf-adhesive and anti-UV herbicide nanoformulation for enhanced herbicidal activity	54
Restoring mitochondrial lipid homeostasis with arachidonic acid supplementation to alleviate cognitive impairment in schizophrenia patients	54
Human serum albumin-derived biosensor for visualizing copper(II) and hydrogen sulfide interactions in cancer cells	54
Rationally designed BCR-ABL kinase inhibitors for improved leukemia treatment via covalent and pro-/dual-drug targeting strategies	53
Snapin mediates neuronal PANoptosis after mild traumatic brain injury via H2S-dependent S-sulfhydration of CTSD	53
SAMD4A inhibits abdominal aortic aneurysm development and VSMC phenotypic transformation through targeting KDM2B	53
Beneficial effect of capsaicin via TRPV4/EDH signals on mesenteric arterioles of normal and colitis mice	53
HIF-1α inhibition by MO-2097, a novel chiral-free benzofuran targeting hnRNPA2B1	53
Metabolic interactions drive microbial community succession and functional expression of Nongxiangxing (Strong-flavor) daqu	52
Intracellular Fusobacterium nucleatum infection increases METTL3-mediated m6A methylation to promote the metastasis of esophageal squamous cell carcinoma	52
Insomnia: the gut microbiome connection, prospects for probiotic and postbiotic therapies, and future directions	52
CD34+CLDN5+ tumor associated senescent endothelial cells through IGF2-IGF2R signaling increased cholangiocellular phenotype in hepatocellular carcinoma	52
Dose-effect of polystyrene microplastics on digestive toxicity in chickens (Gallus gallus): Multi-omics reveals critical role of gut-liver axis	52
Advanced colorectal neoplasia and colorectal cancer in metabolic dysfunction-associated steatotic liver disease	52
Mass spectrometry unveils heat-induced changes in yolk oxylipins and key lipid molecules during home cooking	51
Brain-targeted autoimmunity is strongly associated with Long COVID and its chronic fatigue syndrome as well as its affective symptoms	51
Synthetic tunable promoters for flexible control of multi-gene expression in mammalian cells	51
YAP/TAZ, beta-catenin, and TGFb pathway activation in medical plasma-induced wound healing in diabetic mice	51
Anti-inflammatory therapy in hepatic encephalopathy: A systematic review and meta-analysis	50
The miR408a-BBP-LAC3/CSD1 module regulates anthocyanin biosynthesis mediated by crosstalk between copper homeostasis and ROS homeostasis during light induction in Malus plants	50
Editorial Board	50
Editorial Board	50
Alarm: Retracted articles on cancer imaging are not only continuously cited by publications but also used by ChatGPT to answer questions	49
Nicotinamide riboside alleviates ionizing radiation-induced intestinal senescence by alleviating oxidative damage and regulating intestinal metabolism	49
Multi-omics reveals an ecdysone-activated Eip75B-FABP signaling axis coordinating nutrient metabolism for development in Hermetia illucens	49
Small nucleolar RNAs and SNHGs in the intestinal mucosal barrier: Emerging insights and current roles	49
FGF21-FGFR1 signaling protects against cardiac hypertrophy by regulating PINK1-mediated mitophagy pathway	49
Alanine metabolism mediates energy allocation of the brown planthopper to adapt to resistant rice	49
Genotype-driven variations in lncRNA expression underlie predisposition to high-grade serous ovarian cancer	49
Modulating GRP75 to restore calcium homeostasis: a novel neuroprotective strategy of CRSE6# in Parkinson’s disease models	48
Shikonin nasal spray film preparation promoted the repair of nasal mucosal injury by the interaction of shikonin with interleukin-6	48
Sympathetic innervation induces exosomal miR-125 transfer from osteoarthritic chondrocytes, disrupting subchondral bone homeostasis and aggravating cartilage damage in aging mice	48
Construction of musculoskeletal quantitative model based on deep learning and study of musculoskeletal relationship in patients with osteoporosis	48
Graphdiyne as an emerging sensor platform: Principles, synthesis and application	48
Temporal variability of urinary microcystin-LR concentrations in healthy adult men: Recommendations for sampling strategy	48
Unraveling the anti-corrosion mechanisms of a novel hydrazone derivative on steel in contaminated concrete pore solutions: An integrated study	48
Aging induces sarcopenia by disrupting the crosstalk between the skeletal muscle microenvironment and myofibers	48
HMGB1/STAT3/p65 axis drives microglial activation and autophagy exert a crucial role in chronic Stress-Induced major depressive disorder	47
Cadmium accumulation regulated by a rice heavy-metal importer is harmful for host plant and leaf bacteria	47
Biomechanical research using advanced micro-nano devices: In-Vitro cell Characterization focus	47
Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome	47
Convergent and divergent transcriptional reprogramming of motor and sensory neurons underlying response to peripheral nerve injury	46
The applications of deep learning algorithms on in silico druggable proteins identification	46
Maxillary palp odorant-binding proteins as key mediators of bitter taste and molecular targets for cockroach control	46
Structure-based ligand design and discovery of novel tenuazonic acid derivatives with high herbicidal activity	46
Piezo1 activation accelerates osteoarthritis progression and the targeted therapy effect of artemisinin	46
Global, regional, and national childhood cancer burden, 1990–2019: An analysis based on the Global Burden of Disease Study 2019	45
NRXN3 regulates pyroptosis in intrahepatic cholangiocarcinoma via mediating the phospho-dependent ubiquitination and degradation of caspase-3	45
Berberine suppresses colorectal cancer progression by inducing ferroptosis-mediated energy metabolism disorders	45
AI-enabled language models (LMs) to large language models (LLMs) and multimodal large language models (MLLMs) in drug discovery and development	45

Antifouling applications and fabrications of biomimetic micro-structured surfaces: A review	45
A novel TGR5 agonist Sauchinone ameliorates IMQ induced murine psoriasis by regulating macrophage polarization	45
A natural carotenoid crocin exerts antidepressant action by promoting adult hippocampal neurogenesis through Wnt/β-catenin signaling	45
OTUD7B attenuates renal fibrosis by regulating PRDX1 protein stability	45
Recent research progress and clinical status of immunotherapy for colorectal cancer	45
Targeting CIRP and IL-6R-mediated microglial inflammation to improve outcomes in intracerebral hemorrhage	44
Endothelial NMMHC IIA dissociation from PAR1 activates the CREB3/ARF4 signaling in thrombin-mediated intracerebral hemorrhage	44
Ginsenoside Rb2 inhibits p300-mediated SF3A2 acetylation at lysine 10 to promote Fscn1 alternative splicing against myocardial ischemic/reperfusion injury	44
DAMP signaling networks: from receptors to diverse pathophysiological functions	44
Calcium influx: An essential process by which α-Synuclein regulates morphology of erythrocytes	44
Blockchain and PUF-based secure key establishment protocol for cross-domain digital twins in industrial Internet of Things architecture	43
Beaver behavior optimizer: A novel metaheuristic algorithm for solar PV parameter identification and engineering problems	43
Challenges and advances in the management of inflammation in atherosclerosis	43
Alveolar macrophage-derived TGF-β promotes acute lung injury recovery by regulating inflammatory monocyte-derived macrophages	43
Glycyrrhiza, a commonly used medicinal herb: Review of species classification, pharmacology, active ingredient biosynthesis, and synthetic biology	43
Mitochondrial dysfunction drives ZBP1-mediated PANoptosis to increase the susceptibility of heart failure with preserved ejection fraction-associated atrial fibrillation	43
Title Page	42
Editorial Board	42
Corrigendum to “An updated review and recent advancements in carbon-based bioactive coatings for dental implant applications” [J. Adv. Res. 72 (2025) 265–286]	42
Armodafinil ameliorated fibromyalgia through modulating dopamine and neuroinflammation	42
11-keto-β-boswellic acid and Z-guggulsterone suppress HMGB1/TLR4 pathway activity and modulate microglial polarization to remodel perineuronal nets after nerve injury	42
The urinary eccDNA landscape in prostate cancer reveals associations with genome instability and vital roles in cancer progression	42
Editorial Board	42
Targeting the muscle-brain axis to improve post-stroke cognition via the FNDC5/irisin/BDNF pathway	42
Efficient chemo-immunotherapy leveraging minimalist electrostatic complex nanoparticle as “in situ” vaccine integrated tumor ICD and immunoagonist	42
Study of the sensitization mechanism of immunoassay based on DNA tetrahedron spatial mediation for detecting imidacloprid in vegetables	42
Low-frequency magnetic field therapy for glioblastoma: Current advances, mechanisms, challenges and future perspectives	41
Vinculin mediates a dynamic signal flow underlying cardiac outflow tract development as revealed by single-cell and spatial transcriptomic analysis	41
Eicosapentaenoic acid enhances intestinal stem cell-mediated colonic epithelial regeneration by activating the LSD1-WNT signaling pathway	41
Resuscitation of viable but nonculturable bacteria promoted by ATP-mediated NAD+ synthesis	41
Non-invasive and painless mid-infrared modulation increases collagen in human and mouse skin	40
Beet cyst nematode HsSNARE1 interacts with both AtSNAP2 and AtPR1 and promotes disease in Arabidopsis	40
Illustrating the functional heterogeneity of M-MDSCs to predict sepsis outcomes	40
Targeting acid ceramidase enhances antitumor immune response in colorectal cancer	40
Rational engineering of an antifreeze-based biomaterial with dual-enhanced ice-binding and delivery for high-efficiency cryopreservation	40
IDD10-NAC079 transcription factor complex regulates sheath blight resistance by inhibiting ethylene signaling in rice	39
Synergistic Antitumor Activity and Neuroprotective Effects of FGF1/FGFR Inhibition with Oxaliplatin Chemotherapy	39
Exploring genetic diversity of wild and related tetraploid wheat species Triticum turgidum and Triticum timopheevii	39
Insights of immune cell heterogeneity, tumor-initiated subtype transformation, drug resistance, treatment and detecting technologies in glioma microenvironment	39
NCOA4-Mediated Ferritinophagy Induces Ferroptosis and Enriches Ferritin-Containing EVs via Ferritin Phase Separation to Promote Mechanical Ventilation-Induced Pulmonary Fibrosis	39
Fibroblast-derived BMP5 promotes tendon adhesion by inducing bone marrow mesenchymal stromal cells to differentiate into myofibroblasts	39
Connexin-43 is a promising target for lycopene preventing phthalate-induced spermatogenic disorders	38
Bovine milk microbiota: Key players, origins, and potential contributions to early-life gut development	38
Essential function of Nr4a2 in subicular development and social novelty	38
Cigarette smoke-promoted increases in osteopontin expression attract mesenchymal stem cell recruitment and facilitate lung cancer metastasis	38
Discovery of FBP1 as novel therapeutic target and asiatic acid-hydrogen sulfide donors accelerate diabetic wound healing	38
An ABC transporter-mediated transport and metabolism of the pesticide bentazone in rice (Oryza sativa L.)	38
Sex-specific proteomic signatures improve cardiovascular risk prediction for the general population without cardiovascular disease or diabetes	38
A potential CO2 carrier to improve the utilization of HCO3– by plant-soil ecosystem for carbon sink enhancement	37
Design of a Haversian system-like gradient porous scaffold based on triply periodic minimal surfaces for promoting bone regeneration	37
Urinary Cell-Free DNA detection platform for bacterial cystitis diagnosis via spot-based machine learning	37
Cisplatin and gemcitabine exert opposite effects on immunotherapy with PD-1 antibody in K-ras-driven cancer	37
Integrated stress response activation induced by usnic acid alleviates BCL-2 inhibitor ABT-199 resistance in acute myeloid leukemia	37
The biomedical application of inorganic metal nanoparticles in aging and aging-associated diseases	37
Exercise-Induced Reduction of IGF1R Sumoylation Attenuates Neuroinflammation in APP/PS1 Transgenic Mice	37
Arachidonic acid in aging: New roles for old players	37
A female-biased odorant receptor tuned to the lepidopteran sex pheromone in parasitoid Microplitis mediator guiding habitat of host insects	36
Genome variations reveal rapid adaptation to domestication and habitat changes in the brown algae Saccharina japonica	36
RNA-m5C regulatory atlas of human fetal tissues uncover the activities of Nsun2/Jarid2/Alyref axis	36
Tumour-specific delivery of ω-conotoxin MVIIA via engineered Salmonella for safe anticancer therapy	36
A novel Synthetic phenotype association study approach reveals the landscape of association for genomic variants and phenotypes	36
Moscatilin inhibits vascular calcification by activating IL13RA2-dependent inhibition of STAT3 and attenuating the WNT3/β-catenin signalling pathway	36
Pachymic acid targets PDIA6 to delay mesenchymal stem cell senescence through the G6PD/STAT3 signaling axis and prevent senile osteoporosis	36
Antimicrobial activities of lavandulylated flavonoids in Sophora flavences against methicillin-resistant Staphylococcus aureus via membrane disruption	35
Nervonic acid triggered ovarian inflammation by inducing mitochondrial oxidative stress to activate NLRP3/ IL-1β pathway	35
Marine n-3 fatty acids protect against renal function deterioration in diabetic patients by modulating lipoproteins and promoting cholesterol efflux	35
Ubiquitin proteasome system in cardiac fibrosis	35
Kaempferol regulating macrophage foaming and atherosclerosis through Piezo1-mediated MAPK/NF-κB and Nrf2/HO-1 signaling pathway	35
Plasma proteomics identify novel biomarkers and dynamic patterns of biological aging	35
Dimeric guaianolide sesquiterpenoids from the flowers of Chrysanthemum indicum ameliorate hepatic steatosis through mitigating SIRT1-mediated lipid accumulation and ferroptosis	35
Ginger exosome-like nanoparticle-derived miRNA therapeutics: A strategic inhibitor of intestinal inflammation	35
Long non-coding RNA antisense of insulin-like growth factor 2 receptor promotes osteogenic differentiation by enhancing runt-related transcription factor 2 translation: A potential therapeutic target	34
Role of capsaicin, circadian clock genes, and TRPV1 in colorectal carcinogenesis: Lessons and future directions	34
Transforming growth factor-β receptor 1: An intervention target for genetic poor cartilage quality induced by prenatal dexamethasone exposure	34
Impaired stemness in aging periodontal ligament stem cells is mediated by the progerin/endoplasmic reticulum stress/p53 axis	34
Editorial Board	34
Computational analysis of drug free silver triangular nanoprism theranostic probe plasmonic behavior for in-situ tumor imaging and photothermal therapy	34
Rutin triggers IRE1-mediated GSDMD-dependent pyroptosis in macrophages to suppress systemic Salmonella infection	33
MG53 protects against septic cardiac dysfunction by ubiquitinating ATF2	33
A Composite interaction Score: Prioritizing cell–cell interactions from single-cell RNA-seq with application to pre-menopausal epithelial barriers	33
Dysregulated ITGA3/FAK/YAP axis mediates impaired alveolar type II epithelial cells function in COPD	33
5-Aminolevulinic acid improves strawberry salt tolerance through a NO–H2O2 signaling circuit regulated by FaWRKY70 and FaWRKY40	33
Longitudinal dynamics in frailty and incident all-cause dementia: a multicohort study	33
Bacterial terminal oxidase bo3 as a primary respiratory target of cathelicidin peptide hc-cath against Acinetobacter baumannii	33
Brain Barriers in Normal Pressure Hydrocephalus: Mechanisms and Therapeutic Perspectives	33
Breaking the bottleneck of asthma treatment: the future of omni-targeted therapy	33
Editorial Board	33
Targeting colorectal cancer at the level of nuclear pore complex	32
Transient receptor potential channels in viral infectious diseases: Biological characteristics and regulatory mechanisms	32
Duo-role Platelet-rich Plasma: temperature-induced fibrin gel and growth factors’ reservoir for microneedles to promote hair regrowth	32
Effects of lifestyle and associated diseases on serum CC16 suggest complex interactions among metabolism, heart and lungs	32
Understanding the mechanobiology of phytoacoustics through molecular Lens: Mechanisms and future perspectives	32
Review of research advances in the cerebral lymphatic system and neurological disorders	32
Melanin nanoparticles-loaded lactobacillus fermentum exosomes for targeted and visualized treatment of ulcerative colitis	32
Combinatorial genome engineering of pseudorabies virus Bartha by developing a reverse genetic system based on three overlapping genomic segments	32