OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Advanced Research is 72. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Value of ascitic fluid lipids in the differentiation between cirrhotic and malignant ascites	378
Not only the top: Type I topoisomerases function in multiple tissues and organs development in plants	285
NRIR promotes immune escape in hepatocellular cancer by regulating IFNγ-induced PD-L1 expression	277
STING-driven mitochondrial metabolism reverses cisplatin resistance via MDH2 desuccinylation in non-small cell lung cancer	263
Muscone promotes remyelination and alleviates Parkinson’s disease by targeting FKBP5 in MPTP-induced mouse model	263
Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries	212
Theoretical calculation-experimental collaborative design of integrated coating for degradation regulation and diagnosis-treatment of magnesium alloy for cerebrovascular stents	189
The therapeutic value of “Bile Transfer” for complications of acute pancreatitis: A retrospective clinical study	169
Escherichia coli expressing the kpsM gene exacerbates drug-induced liver injury through up-regulating α1,2-fucosyltransferase and disturbing the host taurine metabolism—from animal models and clinical	167
CHMP4C promotes pancreatic cancer progression by inhibiting necroptosis via the RIPK1/RIPK3/MLKL pathway	158
Long noncoding RNA AC007637.1 inhibits tumorigenesis by regulating the Trim25/PCNA axis in colorectal cancer	153
A multi-omics approach reveals that lotus root polysaccharide iron ameliorates iron deficiency-induced testicular damage by activating PPARγ to promote steroid hormone synthesis	150
Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial growth factor receptor 2 pathway in inflammatory bowel disease	148
Effect of platelet-rich plasma in refractory vitiligo by promoting the differentiation of dermal melanocyte progenitors via IGFBP-2/RhoA/YAP pathway	146
Defect passivation and transformation of Ti3C2Tx MXene hollow microsphere for superior electrochemical performance and sodium-ions storage	145
Autoimmune responses to myelin-associated proteins as diagnostic and prognostic biomarkers of relapsing-remitting multiple sclerosis: Associations with human herpesvirus-6 and Epstein-Barr virus react	141
Lipidomics identified novel cholesterol-independent predictors for risk of incident coronary heart disease: Mediation of risk from diabetes and aggravation of risk by ambient air pollution	136
Synergistic effect of cold gas plasma and experimental drug exposure exhibits skin cancer toxicity in vitro and in vivo	123
Development and validation of dynamic clinical subphenotypes for acute pancreatitis using hematocrit and blood urea nitrogen trajectories in intensive care unit: a multicenter retrospective cohort stu	123
The transcription factor PbbHLH164 is destabilized by PbRAD23C/D.1 and mediates ethylene biosynthesis during pear fruit ripening	122
High throughput screening identifies sanguinarine chloride as a multi-faceted therapeutic agent for PRCC-TFE3 rRCC by targeting lactylation-driven VEGFB-VEGFR2 signaling and PMN-MDSC infiltration	121
Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx	121
Rural-urban disparities in cardiovascular and other competing risk of death among cancer patients	121
H3K27me3-mediated chromatin remodeling governs salt tolerance in cotton via Na+/K+ homeostasis modulation	119
Engineered natural extracellular matrix platform for modelling skin diseases and identifying therapeutic targets	119

Genomic loci associated with leaf abscission contribute to machine picking and environmental adaptability in upland cotton (Gossypium hirsutum L.)	117
Pomegranate peel extract alleviates diabetic retinopathy by suppressing the PI3K/AKT/HIF-1α/VEGF pathway and gut microbiota modulation	115
Lactobacillus johnsonii-derived extracellular vesicles carrying GAPDH protect against ulcerative colitis through modulating macrophage polarization	115
A micropillar array-based microfluidic chip for label-free separation of circulating tumor cells: The best micropillar geometry?	114
SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization	112
Development and clinical validation of a novel protein biomarkers-based algorithm for risk prediction and diagnosis of advanced liver fibrosis: a multi-centre study	110
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD	106
Optimizing therapeutic efficacy of antifungal peptides via strategic terminal amino acid modification	105
Transcriptomic and metabolomic profiles reveal the functions of IGF-1 c.258 A > G synonymous mutation in milk fat content	105
Gossypium purpurascens genome provides insight into the origin and domestication of upland cotton	103
Rab32-based vesicles coordinate mitochondria and actin for spindle migration and organelle rearrangement in oocyte meiosis	102
Interactive canopy nitrogen and water additions delay phenology in a warm-temperate forest	100
Insights into modifiable risk factors of erectile dysfunction, a wide-angled Mendelian Randomization study	99
Unraveling the nexus in the neuro-neoplastic progression of colorectal cancer: Potential role of β2-adrenergic receptor (β2-AR)	99
Four distinct pathways involved in a “tug-of-war” lead to the non-linear nature of phenolic chemistry during lactic acid fermentation of fruits and vegetables	98
RNA methylation modifications in neurodegenerative diseases: Focus on their enzyme system	97
Study of benign prostatic hyperplasia and androgen pathway manipulation on lung cancer survivals	94
Population genomics analyses reveal the role of hybridization in the rapid invasion of fall armyworm	93
The NLRP3 molecule influences the therapeutic effects of mesenchymal stem cells through Glut1-mediated energy metabolic reprogramming	93
Dynamic bidirectional diffusion-controlled multi-enzyme system for one-pot viral detection	93
Advancements in bone organoids: perspectives on construction methodologies and application strategies	93
Injectable Chito-oligosaccharide-hyaluronic acid hydrogels with Fe3+/AMP nano-enzyme promote ROS scavenging and immunomodulation for myocardial infarction repair	90
Kaempferol alleviates myocardial ischemia injury by reducing oxidative stress via the HDAC3-mediated Nrf2 signaling pathway	84
OsCPK9-mediated Thr105 phosphorylation activates OsCATC to enhance drought tolerance in rice	84
c-Myc-PANK3-EMT axis regulates the structure and function of intestinal barrier in ulcerative colitis	84
Adaptive bilirubin nanoscavenger alleviates pulmonary oxidative stress and inflammation for acute lung injury therapy	84
LPCAT3 deficiency Drives phospholipid remodeling and mitochondrial oxidative dysfunction to accelerate MASH-HCC development	83
Targeting fibrillin-1 disrupts the fibrogenic niche formation and ameliorates kidney fibrosis	83
Clostridium butyricum and its metabolites regulate macrophage polarization through miR-146a to antagonize gouty arthritis	82
Clinical evaluation of cell-free and cellular metagenomic next-generation sequencing of infected body fluids	81
Applications of single-cell analysis in immunotherapy for lung cancer: Current progress, new challenges and expectations	81
Association between dietary amino acid intake and the risk of metabolic dysfunction-associated steatotic liver disease	80
Redox status of the plant cell determines epigenetic modifications under abiotic stress conditions and during developmental processes	80
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism	79
Unraveling competitive protein interactions: A critical step toward improved production and therapeutics	79
Forsythiaside A alleviates acute lung injury by inhibiting inflammation and epithelial barrier damages in lung and colon through PPAR-γ/RXR-α complex	79
Functions of FGF21 and its role in cardiac hypertrophy	79
Tissue-resolved molecular landscape reveals hepatic regulatory networks and metabolic mediators underlying feed efficiency in chickens	78
Digital techniques and trends for seed phenotyping using optical sensors	78
TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway	78
Lactation duration and the risk of type 2 diabetes mellitus in parous women: A perspective on socioeconomic status disparity	76
Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells	74
A “DUBTAC” targeting GLUL deubiquitination promotes BMSC osteogenic differentiation and implant osseointegration in type 2 diabetes	74
Full dimensional dynamic 3D convolution and point cloud in pulmonary nodule detection	74
The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology	73
Computational glycosyltransferases masked deoxynivalenol toxicity and halted FHB spread in wheat grains	73
Title Page	72
An increase in DNA methylation contributes to anthocyanin biosynthesis in the pericarp as litchi (Litchi chinensis Sonn.) fruit ripens	72
Editorial Board	72