OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Advanced Research is 69. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Value of ascitic fluid lipids in the differentiation between cirrhotic and malignant ascites	361
Not only the top: Type I topoisomerases function in multiple tissues and organs development in plants	274
OsCPK9-mediated Thr105 phosphorylation activates OsCATC to enhance drought tolerance in rice	264
RNA methylation modifications in neurodegenerative diseases: Focus on their enzyme system	240
NRIR promotes immune escape in hepatocellular cancer by regulating IFNγ-induced PD-L1 expression	231
Pomegranate peel extract alleviates diabetic retinopathy by suppressing the PI3K/AKT/HIF-1α/VEGF pathway and gut microbiota modulation	195
c-Myc-PANK3-EMT axis regulates the structure and function of intestinal barrier in ulcerative colitis	179
Gossypium purpurascens genome provides insight into the origin and domestication of upland cotton	153
The transcription factor PbbHLH164 is destabilized by PbRAD23C/D.1 and mediates ethylene biosynthesis during pear fruit ripening	151
Unraveling competitive protein interactions: A critical step toward improved production and therapeutics	141
Rural-urban disparities in cardiovascular and other competing risk of death among cancer patients	140
Transcriptomic and metabolomic profiles reveal the functions of IGF-1 c.258 A > G synonymous mutation in milk fat content	138
A micropillar array-based microfluidic chip for label-free separation of circulating tumor cells: The best micropillar geometry?	138
LPCAT3 deficiency Drives phospholipid remodeling and mitochondrial oxidative dysfunction to accelerate MASH-HCC development	133
Development and validation of dynamic clinical subphenotypes for acute pancreatitis using hematocrit and blood urea nitrogen trajectories in intensive care unit: a multicenter retrospective cohort stu	131
High throughput screening identifies sanguinarine chloride as a multi-faceted therapeutic agent for PRCC-TFE3 rRCC by targeting lactylation-driven VEGFB-VEGFR2 signaling and PMN-MDSC infiltration	130
Clinical evaluation of cell-free and cellular metagenomic next-generation sequencing of infected body fluids	130
Tissue-resolved molecular landscape reveals hepatic regulatory networks and metabolic mediators underlying feed efficiency in chickens	125
Muscone promotes remyelination and alleviates Parkinson’s disease by targeting FKBP5 in MPTP-induced mouse model	118
STING-driven mitochondrial metabolism reverses cisplatin resistance via MDH2 desuccinylation in non-small cell lung cancer	118
H3K27me3-mediated chromatin remodeling governs salt tolerance in cotton via Na+/K+ homeostasis modulation	117
TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway	113
Clostridium butyricum and its metabolites regulate macrophage polarization through miR-146a to antagonize gouty arthritis	113
Advancements in bone organoids: perspectives on construction methodologies and application strategies	110
Rab32-based vesicles coordinate mitochondria and actin for spindle migration and organelle rearrangement in oocyte meiosis	110

Theoretical calculation-experimental collaborative design of integrated coating for degradation regulation and diagnosis-treatment of magnesium alloy for cerebrovascular stents	110
Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries	110
Association between dietary amino acid intake and the risk of metabolic dysfunction-associated steatotic liver disease	106
Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial growth factor receptor 2 pathway in inflammatory bowel disease	105
Applications of single-cell analysis in immunotherapy for lung cancer: Current progress, new challenges and expectations	101
The therapeutic value of “Bile Transfer” for complications of acute pancreatitis: A retrospective clinical study	100
Escherichia coli expressing the kpsM gene exacerbates drug-induced liver injury through up-regulating α1,2-fucosyltransferase and disturbing the host taurine metabolism—from animal models and clinical	97
SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization	97
Defect passivation and transformation of Ti3C2Tx MXene hollow microsphere for superior electrochemical performance and sodium-ions storage	97
Adaptive bilirubin nanoscavenger alleviates pulmonary oxidative stress and inflammation for acute lung injury therapy	97
CHMP4C promotes pancreatic cancer progression by inhibiting necroptosis via the RIPK1/RIPK3/MLKL pathway	94
Insights into modifiable risk factors of erectile dysfunction, a wide-angled Mendelian Randomization study	92
Long noncoding RNA AC007637.1 inhibits tumorigenesis by regulating the Trim25/PCNA axis in colorectal cancer	91
Autoimmune responses to myelin-associated proteins as diagnostic and prognostic biomarkers of relapsing-remitting multiple sclerosis: Associations with human herpesvirus-6 and Epstein-Barr virus react	90
A multi-omics approach reveals that lotus root polysaccharide iron ameliorates iron deficiency-induced testicular damage by activating PPARγ to promote steroid hormone synthesis	90
Engineered natural extracellular matrix platform for modelling skin diseases and therapeutic targets discovery	90
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD	88
Synergistic effect of cold gas plasma and experimental drug exposure exhibits skin cancer toxicity in vitro and in vivo	86
Population genomics analyses reveal the role of hybridization in the rapid invasion of fall armyworm	83
Unraveling the nexus in the neuro-neoplastic progression of colorectal cancer: Potential role of β2-adrenergic receptor (β2-AR)	83
Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx	82
Digital techniques and trends for seed phenotyping using optical sensors	80
Lipidomics identified novel cholesterol-independent predictors for risk of incident coronary heart disease: Mediation of risk from diabetes and aggravation of risk by ambient air pollution	79
Redox status of the plant cell determines epigenetic modifications under abiotic stress conditions and during developmental processes	79
Development and clinical validation of a novel protein biomarkers-based algorithm for risk prediction and diagnosis of advanced liver fibrosis: a multi-centre study	78
Forsythiaside A alleviates acute lung injury by inhibiting inflammation and epithelial barrier damages in lung and colon through PPAR-γ/RXR-α complex	78
The NLRP3 molecule influences the therapeutic effects of mesenchymal stem cells through Glut1-mediated energy metabolic reprogramming	77
Genomic loci associated with leaf abscission contribute to machine picking and environmental adaptability in upland cotton (Gossypium hirsutum L.)	77
Four distinct pathways involved in a “tug-of-war” lead to the non-linear nature of phenolic chemistry during lactic acid fermentation of fruits and vegetables	77
Kaempferol alleviates myocardial ischemia injury by reducing oxidative stress via the HDAC3-mediated Nrf2 signaling pathway	76
Functions of FGF21 and its role in cardiac hypertrophy	76
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism	76
Effect of platelet-rich plasma in refractory vitiligo by promoting the differentiation of dermal melanocyte progenitors via IGFBP-2/RhoA/YAP pathway	75
Optimizing therapeutic efficacy of antifungal peptides via strategic terminal amino acid modification	75
Lactobacillus johnsonii-derived extracellular vesicles carrying GAPDH protect against ulcerative colitis through modulating macrophage polarization	75
S-sulfhydration: Novel insights into the antioxidant and antiinflammation in age-related diseases	74
Full dimensional dynamic 3D convolution and point cloud in pulmonary nodule detection	74
A “DUBTAC” targeting GLUL deubiquitination promotes BMSC osteogenic differentiation and implant osseointegration in type 2 diabetes	74
Lactation duration and the risk of type 2 diabetes mellitus in parous women: A perspective on socioeconomic status disparity	74
Strain specificity of lactobacilli with promoted colonization by galactooligosaccharides administration in protecting intestinal barriers during Salmonella infection	73
The BET inhibitor JQ1 targets fat metabolism and counteracts obesity	71
Consistency and reproducibility of large panel next-generation sequencing: Multi-laboratory assessment of somatic mutation detection on reference materials with mismatch repair and proofreading defici	70
The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology	70
Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells	70
Computational glycosyltransferases masked deoxynivalenol toxicity and halted FHB spread in wheat grains	69
Enhanced tuberculosis control via leveraging dendritic cell-mediated Th1 responses in preventive and immunotherapeutic vaccine strategies	69