OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Advanced Research is 69. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Value of ascitic fluid lipids in the differentiation between cirrhotic and malignant ascites	355
Not only the top: Type I topoisomerases function in multiple tissues and organs development in plants	351
OsCPK9-mediated Thr105 phosphorylation activates OsCATC to enhance drought tolerance in rice	269
RNA methylation modifications in neurodegenerative diseases: Focus on their enzyme system	260
NRIR promotes immune escape in hepatocellular cancer by regulating IFNγ-induced PD-L1 expression	259
Pomegranate peel extract alleviates diabetic retinopathy by suppressing the PI3K/AKT/HIF-1α/VEGF pathway and gut microbiota modulation	235
The NLRP3 molecule influences the therapeutic effects of mesenchymal stem cells through Glut1-mediated energy metabolic reprogramming	233
Population genomics analyses reveal the role of hybridization in the rapid invasion of fall armyworm	232
Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx	215
Adaptive bilirubin nanoscavenger alleviates pulmonary oxidative stress and inflammation for acute lung injury therapy	191
Redox status of the plant cell determines epigenetic modifications under abiotic stress conditions and during developmental processes	170
c-Myc-PANK3-EMT axis regulates the structure and function of intestinal barrier in ulcerative colitis	153
Gossypium purpurascens genome provides insight into the origin and domestication of upland cotton	148
Genomic loci associated with leaf abscission contribute to machine picking and environmental adaptability in upland cotton (Gossypium hirsutum L.)	143
The transcription factor PbbHLH164 is destabilized by PbRAD23C/D.1 and mediates ethylene biosynthesis during pear fruit ripening	140
Theoretical calculation-experimental collaborative design of integrated coating for degradation regulation and diagnosis-treatment of magnesium alloy for cerebrovascular stents	137
Effect of platelet-rich plasma in refractory vitiligo by promoting the differentiation of dermal melanocyte progenitors via IGFBP-2/RhoA/YAP pathway	135
Unraveling competitive protein interactions: A critical step toward improved production and therapeutics	133
Escherichia coli expressing the kpsM gene exacerbates drug-induced liver injury through up-regulating α1,2-fucosyltransferase and disturbing the host taurine metabolism—from animal models and clinical	126
Transcriptomic and metabolomic profiles reveal the functions of IGF-1 c.258 A > G synonymous mutation in milk fat content	125
Rural-urban disparities in cardiovascular and other competing risk of death among cancer patients	125
Development and clinical validation of a novel protein biomarkers-based algorithm for risk prediction and diagnosis of advanced liver fibrosis: a multi-centre study	122
Four distinct pathways involved in a “tug-of-war” lead to the non-linear nature of phenolic chemistry during lactic acid fermentation of fruits and vegetables	116
A multi-omics approach reveals that lotus root polysaccharide iron ameliorates iron deficiency-induced testicular damage by activating PPARγ to promote steroid hormone synthesis	115
Lipidomics identified novel cholesterol-independent predictors for risk of incident coronary heart disease: Mediation of risk from diabetes and aggravation of risk by ambient air pollution	114

Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries	113
Applications of single-cell analysis in immunotherapy for lung cancer: Current progress, new challenges and expectations	109
Defect passivation and transformation of Ti3C2Tx MXene hollow microsphere for superior electrochemical performance and sodium-ions storage	109
Rab32-based vesicles coordinate mitochondria and actin for spindle migration and organelle rearrangement in oocyte meiosis	109
Lactobacillus johnsonii-derived extracellular vesicles carrying GAPDH protect against ulcerative colitis through modulating macrophage polarization	108
Optimizing therapeutic efficacy of antifungal peptides via strategic terminal amino acid modification	106
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism	104
High throughput screening identifies sanguinarine chloride as a multi-faceted therapeutic agent for PRCC-TFE3 rRCC by targeting lactylation-driven VEGFB-VEGFR2 signaling and PMN-MDSC infiltration	103
Tissue-resolved molecular landscape reveals hepatic regulatory networks and metabolic mediators underlying feed efficiency in chickens	102
Muscone promotes remyelination and alleviates Parkinson’s disease by targeting FKBP5 in MPTP-induced mouse model	97
H3K27me3-mediated chromatin remodeling governs salt tolerance in cotton via Na+/K+ homeostasis modulation	96
STING-driven mitochondrial metabolism reverses cisplatin resistance via MDH2 desuccinylation in non-small cell lung cancer	96
LPCAT3 deficiency Drives phospholipid remodeling and mitochondrial oxidative dysfunction to accelerate MASH-HCC development	95
Association between dietary amino acid intake and the risk of metabolic dysfunction-associated steatotic liver disease	95
Functions of FGF21 and its role in cardiac hypertrophy	92
The therapeutic value of “Bile Transfer” for complications of acute pancreatitis: A retrospective clinical study	91
Unraveling the nexus in the neuro-neoplastic progression of colorectal cancer: Potential role of β2-adrenergic receptor (β2-AR)	90
Development and validation of dynamic clinical subphenotypes for acute pancreatitis using hematocrit and blood urea nitrogen trajectories in intensive care unit: a multicenter retrospective cohort stu	89
Long noncoding RNA AC007637.1 inhibits tumorigenesis by regulating the Trim25/PCNA axis in colorectal cancer	89
Advancements in bone organoids: perspectives on construction methodologies and application strategies	86
Clinical evaluation of cell-free and cellular metagenomic next-generation sequencing of infected body fluids	85
Digital techniques and trends for seed phenotyping using optical sensors	84
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD	82
Synergistic effect of cold gas plasma and experimental drug exposure exhibits skin cancer toxicity in vitro and in vivo	80
CHMP4C promotes pancreatic cancer progression by inhibiting necroptosis via the RIPK1/RIPK3/MLKL pathway	80
TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway	78
Forsythiaside A alleviates acute lung injury by inhibiting inflammation and epithelial barrier damages in lung and colon through PPAR-γ/RXR-α complex	76
A micropillar array-based microfluidic chip for label-free separation of circulating tumor cells: The best micropillar geometry?	76
Kaempferol alleviates myocardial ischemia injury by reducing oxidative stress via the HDAC3-mediated Nrf2 signaling pathway	75
SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization	75
Autoimmune responses to myelin-associated proteins as diagnostic and prognostic biomarkers of relapsing-remitting multiple sclerosis: Associations with human herpesvirus-6 and Epstein-Barr virus react	74
Clostridium butyricum and its metabolites regulate macrophage polarization through miR-146a to antagonize gouty arthritis	74
A “DUBTAC” targeting GLUL deubiquitination promotes BMSC osteogenic differentiation and implant osseointegration in type 2 diabetes	73
S-sulfhydration: Novel insights into the antioxidant and antiinflammation in age-related diseases	73
Design of highly leaf-adhesive and anti-UV herbicide nanoformulation for enhanced herbicidal activity	73
Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial growth factor receptor 2 pathway in inflammatory bowel disease	73
Lactation duration and the risk of type 2 diabetes mellitus in parous women: A perspective on socioeconomic status disparity	73
Insights into modifiable risk factors of erectile dysfunction, a wide-angled Mendelian Randomization study	73
SLC7A11 as a therapeutic target to attenuate phthalates-driven testosterone level decline in mice	72
Rationally designed BCR-ABL kinase inhibitors for improved leukemia treatment via covalent and pro-/dual-drug targeting strategies	72
Full dimensional dynamic 3D convolution and point cloud in pulmonary nodule detection	71
The BET inhibitor JQ1 targets fat metabolism and counteracts obesity	69
CD34+CLDN5+ tumor associated senescent endothelial cells through IGF2-IGF2R signaling increased cholangiocellular phenotype in hepatocellular carcinoma	69
Strain specificity of lactobacilli with promoted colonization by galactooligosaccharides administration in protecting intestinal barriers during Salmonella infection	69
Consistency and reproducibility of large panel next-generation sequencing: Multi-laboratory assessment of somatic mutation detection on reference materials with mismatch repair and proofreading defici	69
Restoring mitochondrial lipid homeostasis with arachidonic acid supplementation to alleviate cognitive impairment in schizophrenia patients	69