OOIR: Observatory of International Research

Papers

(The H4-Index of Cells is 87. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Management of Rheumatoid Arthritis: An Overview	366
Role of Structural and Non-Structural Proteins and Therapeutic Targets of SARS-CoV-2 for COVID-19	315
Influence of Nitrogen and Phosphorus on Microalgal Growth, Biomass, Lipid, and Fatty Acid Production: An Overview	300
Oxidative Stress in Human Pathology and Aging: Molecular Mechanisms and Perspectives	296
High-Fat, Western-Style Diet, Systemic Inflammation, and Gut Microbiota: A Narrative Review	290
Mechanisms of Metabolic Reprogramming in Cancer Cells Supporting Enhanced Growth and Proliferation	278
Cyclin D1 in Cancer: A Molecular Connection for Cell Cycle Control, Adhesion and Invasion in Tumor and Stroma	240
Mesenchymal Stem Cell-Derived Exosomes: Applications in Regenerative Medicine	221
Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs	221
Epithelial-Mesenchymal Transition (EMT): The Type-2 EMT in Wound Healing, Tissue Regeneration and Organ Fibrosis	204
Role of Cardiac Macrophages on Cardiac Inflammation, Fibrosis and Tissue Repair	202
Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease	201
Sarcoidosis: A Clinical Overview from Symptoms to Diagnosis	200
Macrophages in Lung Injury, Repair, and Fibrosis	200
COVID-19: Characteristics and Therapeutics	194
The Role of MSC in Wound Healing, Scarring and Regeneration	190
Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment	187
Loop-Mediated Isothermal Amplification (LAMP): The Better Sibling of PCR?	187
New Onset of Autoimmune Diseases Following COVID-19 Diagnosis	168
Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health	168
Hypoxia, Metabolic Reprogramming, and Drug Resistance in Liver Cancer	161
Insights into the Interactions among Roots, Rhizosphere, and Rhizobacteria for Improving Plant Growth and Tolerance to Abiotic Stresses: A Review	155
Effects of Salinity Stress on Chloroplast Structure and Function	152
The RHO Family GTPases: Mechanisms of Regulation and Signaling	151
Extracellular ATP: A Feasible Target for Cancer Therapy	150

Cardiovascular Manifestations of COVID-19 Infection	149
Doxorubicin—An Agent with Multiple Mechanisms of Anticancer Activity	147
Comprehensive Structural and Molecular Comparison of Spike Proteins of SARS-CoV-2, SARS-CoV and MERS-CoV, and Their Interactions with ACE2	147
Chronic Diabetic Wounds and Their Treatment with Skin Substitutes	143
Dopamine: The Neuromodulator of Long-Term Synaptic Plasticity, Reward and Movement Control	142
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations	137
The Role of Mitochondria in Oocyte Maturation	136
GSK-3 and Tau: A Key Duet in Alzheimer’s Disease	135
Immune Infiltrates in Breast Cancer: Recent Updates and Clinical Implications	129
ERK: A Double-Edged Sword in Cancer. ERK-Dependent Apoptosis as a Potential Therapeutic Strategy for Cancer	128
A Universal Approach to Analyzing Transmission Electron Microscopy with ImageJ	127
Significance of Interleukin (IL)-4 and IL-13 in Inflammatory Arthritis	126
Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications	125
Inflammatory Cytokines in Cancer: Comprehensive Understanding and Clinical Progress in Gene Therapy	124
The Function of Cumulus Cells in Oocyte Growth and Maturation and in Subsequent Ovulation and Fertilization	124
Gut Microbiota-Derived Tryptophan Metabolites Maintain Gut and Systemic Homeostasis	122
Heme Oxgenase-1, a Cardinal Modulator of Regulated Cell Death and Inflammation	121
The Role of Macrophages in the Development of Acute and Chronic Inflammatory Lung Diseases	120
The Role of Oxidative Stress in Atherosclerosis	120
Innovative Treatment Strategies to Accelerate Wound Healing: Trajectory and Recent Advancements	119
Cell Death and Inflammation: The Role of Mitochondria in Health and Disease	119
Beyond Activation: Characterizing Microglial Functional Phenotypes	119
Future Directions in the Treatment of Osteosarcoma	117
Regulation of TNF-Induced Osteoclast Differentiation	117
Microglia Phenotypes in Aging and Neurodegenerative Diseases	116
CHEK2 Germline Variants in Cancer Predisposition: Stalemate Rather than Checkmate	115
Fibronectin: Molecular Structure, Fibrillar Structure and Mechanochemical Signaling	114
Cellular and Molecular Mechanisms Underlying Liver Fibrosis Regression	113
Molecular and Hormonal Mechanisms Regulating Fleshy Fruit Ripening	113
Biostimulants for the Regulation of Reactive Oxygen Species Metabolism in Plants under Abiotic Stress	112
Calcium Signaling Regulates Autophagy and Apoptosis	110
Macrophage Reprogramming and Cancer Therapeutics: Role of iNOS-Derived NO	109
Inflammatory Chemokines in Atherosclerosis	108
Neuroprotective Natural Products for Alzheimer’s Disease	108
Signaling Pathways in Cancer: Therapeutic Targets, Combinatorial Treatments, and New Developments	104
Extracellular Vesicles under Oxidative Stress Conditions: Biological Properties and Physiological Roles	101
Interconnections between Inflammageing and Immunosenescence during Ageing	101
Retinoic Acid and Its Derivatives in Skin	101
Cancer Stem Cells: Significance in Origin, Pathogenesis and Treatment of Glioblastoma	100
Vascular Dysfunction in Preeclampsia	99
Regulation of Cell Cycle Progression by Growth Factor-Induced Cell Signaling	99
Molecular Markers and Targets in Melanoma	97
Metabolomics in Diabetes and Diabetic Complications: Insights from Epidemiological Studies	95
Emerging Role of cAMP/AMPK Signaling	95
Neuron-Astrocyte Interactions in Parkinson’s Disease	95
The Role of Th17 Response in COVID-19	94
Myeloid Cells in Glioblastoma Microenvironment	94
Biosynthesis and Functions of Very-Long-Chain Fatty Acids in the Responses of Plants to Abiotic and Biotic Stresses	94
Recent Advances in Understanding the Pathogenesis of Rheumatoid Arthritis: New Treatment Strategies	93
GBA Variants and Parkinson Disease: Mechanisms and Treatments	93

Spermine: Its Emerging Role in Regulating Drought Stress Responses in Plants	92
Molecular Mechanisms of mtDNA-Mediated Inflammation	91
Mitophagy: Molecular Mechanisms, New Concepts on Parkin Activation and the Emerging Role of AMPK/ULK1 Axis	91
Macrophage-Mediated Inflammation in Skin Wound Healing	90
SARS-CoV-2 Nucleocapsid Protein Targets RIG-I-Like Receptor Pathways to Inhibit the Induction of Interferon Response	90
Circulating Platelet-Derived Extracellular Vesicles Are a Hallmark of Sars-Cov-2 Infection	89
The Role of HO-1 and Its Crosstalk with Oxidative Stress in Cancer Cell Survival	89
Unraveling Cell Death Pathways during Malaria Infection: What Do We Know So Far?	89
Insulin Resistance and Diabetes Mellitus in Alzheimer’s Disease	89
Vascular Endothelial Cells: Heterogeneity and Targeting Approaches	89
Pathogenesis of Endometriosis: The Origin of Pain and Subfertility	88
Ubiquitination-Proteasome System (UPS) and Autophagy Two Main Protein Degradation Machineries in Response to Cell Stress	87
Innate Immune Cell Death in Neuroinflammation and Alzheimer’s Disease	87
Cytokine-Mediated Crosstalk between Immune Cells and Epithelial Cells in the Gut	87