Cancers

Papers
(The median citation count of Cancers is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Breast Cancer—Epidemiology, Risk Factors, Classification, Prognostic Markers, and Current Treatment Strategies—An Updated Review656
A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis402
Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies293
CA125 and Ovarian Cancer: A Comprehensive Review246
Organoid and Spheroid Tumor Models: Techniques and Applications236
Recent Advances in Zinc Oxide Nanoparticles (ZnO NPs) for Cancer Diagnosis, Target Drug Delivery, and Treatment234
STING Agonists as Cancer Therapeutics222
Epidemiology of Glioblastoma Multiforme–Literature Review210
EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance206
The Role of Tumor Microenvironment in Cancer Metastasis: Molecular Mechanisms and Therapeutic Opportunities202
PD-L1, TMB, MSI, and Other Predictors of Response to Immune Checkpoint Inhibitors in Biliary Tract Cancer191
The Role of Macrophages in Cancer Development and Therapy188
Vimentin Is at the Heart of Epithelial Mesenchymal Transition (EMT) Mediated Metastasis188
The Pathogenic Role of PI3K/AKT Pathway in Cancer Onset and Drug Resistance: An Updated Review181
Immune Checkpoint Inhibitors for the Treatment of Bladder Cancer174
Obesity and Cancer: A Current Overview of Epidemiology, Pathogenesis, Outcomes, and Management168
Mechanisms of Cisplatin-Induced Acute Kidney Injury: Pathological Mechanisms, Pharmacological Interventions, and Genetic Mitigations166
Talimogene Laherparepvec (T-VEC): An Intralesional Cancer Immunotherapy for Advanced Melanoma165
Photodynamic Therapy: A Compendium of Latest Reviews164
Apoptosis Deregulation and the Development of Cancer Multi-Drug Resistance157
Breast Cancer—Epidemiology, Classification, Pathogenesis and Treatment (Review of Literature)153
Novel Transfer Learning Approach for Medical Imaging with Limited Labeled Data152
IL-12 Family Cytokines in Cancer and Immunotherapy149
Chemotherapy Side-Effects: Not All DNA Damage Is Equal144
Emerging Therapies for Hepatocellular Carcinoma (HCC)143
The Role of p53 Signaling in Colorectal Cancer140
The Multifaceted Roles of Copper in Cancer: A Trace Metal Element with Dysregulated Metabolism, but Also a Target or a Bullet for Therapy139
Lactate in the Tumor Microenvironment: An Essential Molecule in Cancer Progression and Treatment137
The Role of Probiotics in Cancer Prevention133
HER2-Low Breast Cancer: Molecular Characteristics and Prognosis131
MAPK/ERK Signaling Pathway in Hepatocellular Carcinoma131
RGD-Binding Integrins Revisited: How Recently Discovered Functions and Novel Synthetic Ligands (Re-)Shape an Ever-Evolving Field126
FLASH Proton Pencil Beam Scanning Irradiation Minimizes Radiation-Induced Leg Contracture and Skin Toxicity in Mice126
Global Burden, Risk Factors, and Trends of Esophageal Cancer: An Analysis of Cancer Registries from 48 Countries126
Application of Artificial Intelligence Technology in Oncology: Towards the Establishment of Precision Medicine126
Recurrent Glioblastoma: From Molecular Landscape to New Treatment Perspectives124
The Role of Cancer-Associated Fibroblasts in Cancer Invasion and Metastasis123
The Role of Cancer-Associated Fibroblasts in Tumor Progression122
Targeting BCL-2 in Cancer: Advances, Challenges, and Perspectives121
The Role of Tumor Microenvironment in Multiple Myeloma Development and Progression119
Cancer and Aging: Two Tightly Interconnected Biological Processes117
Mechanisms of Taxane Resistance116
The Role of Oxidative Stress and Its Counteractive Utility in Colorectal Cancer (CRC)113
Oral–Gut Microbiome Axis in Gastrointestinal Disease and Cancer112
A Review of Circulating Tumour Cell Enrichment Technologies112
The KEAP1–NRF2 System as a Molecular Target of Cancer Treatment110
Immune Escape Mechanisms in Non Small Cell Lung Cancer110
Current Landscape of Non-Small Cell Lung Cancer: Epidemiology, Histological Classification, Targeted Therapies, and Immunotherapy110
Recent Advancements in Stimuli Responsive Drug Delivery Platforms for Active and Passive Cancer Targeting110
Hedgehog/GLI Signaling Pathway: Transduction, Regulation, and Implications for Disease110
Arginine Signaling and Cancer Metabolism109
Worldwide Burden, Risk Factors, and Temporal Trends of Ovarian Cancer: A Global Study108
The Role of Artificial Intelligence in Early Cancer Diagnosis107
Ki-67 as a Prognostic Biomarker in Invasive Breast Cancer107
Immune Resistance in Lung Adenocarcinoma107
Neutrophil Extracellular Traps (NETs) in Cancer Invasion, Evasion and Metastasis106
Stimuli-Responsive Hydrogels for Cancer Treatment: The Role of pH, Light, Ionic Strength and Magnetic Field105
CTLA-4 in Regulatory T Cells for Cancer Immunotherapy104
Anticancer Therapy with HDAC Inhibitors: Mechanism-Based Combination Strategies and Future Perspectives103
Emerging Insights into Targeted Therapy-Tolerant Persister Cells in Cancer103
Oxidative Stress in the Tumor Microenvironment and Its Relevance to Cancer Immunotherapy103
3D Cell Culture Models as Recapitulators of the Tumor Microenvironment for the Screening of Anti-Cancer Drugs102
New Pathological and Clinical Insights in Endometrial Cancer in View of the Updated ESGO/ESTRO/ESP Guidelines102
MMP9: A Tough Target for Targeted Therapy for Cancer101
The Functional Crosstalk between Myeloid-Derived Suppressor Cells and Regulatory T Cells within the Immunosuppressive Tumor Microenvironment101
Light Technology for Efficient and Effective Photodynamic Therapy: A Critical Review100
Glucose Transporters as a Target for Anticancer Therapy99
Tumor Hypoxia as a Barrier in Cancer Therapy: Why Levels Matter98
Impact of the COVID-19 Pandemic on Cancer Diagnoses in General and Specialized Practices in Germany97
Triple Negative Breast Cancer: Updates on Classification and Treatment in 202196
The Exciting New Field of HER2-Low Breast Cancer Treatment96
MicroRNA Therapeutics in Cancer: Current Advances and Challenges95
Cancer-Associated Fibroblasts: Tumorigenicity and Targeting for Cancer Therapy95
Surgical Management of the Axilla in Clinically Node-Positive Breast Cancer Patients Converting to Clinical Node Negativity through Neoadjuvant Chemotherapy: Current Status, Knowledge Gaps, and Ration95
The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy94
Transfer Learning in Breast Cancer Diagnoses via Ultrasound Imaging93
Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis92
An Updated Review on Head and Neck Cancer Treatment with Radiation Therapy92
Cyclic Hypoxia: An Update on Its Characteristics, Methods to Measure It and Biological Implications in Cancer92
Update on Prevalence of Pain in Patients with Cancer 2022: A Systematic Literature Review and Meta-Analysis92
Tumor Heterogeneity in Glioblastomas: From Light Microscopy to Molecular Pathology91
The Functional Role of Extracellular Matrix Proteins in Cancer90
Mechanisms of Resistance to KRASG12C Inhibitors90
A Systematic Review of Biosynthesized Metallic Nanoparticles as a Promising Anti-Cancer-Strategy90
Cancer Stem Cells—Key Players in Tumor Relapse90
Impact of the Tumor Microenvironment on Tumor Heterogeneity and Consequences for Cancer Cell Plasticity and Stemness89
Lymphopenia as a Biological Predictor of Outcomes in COVID-19 Patients: A Nationwide Cohort Study89
Osteopontin: A Key Regulator of Tumor Progression and Immunomodulation89
Targeting PI3K/AKT/mTOR Signaling Pathway in Breast Cancer88
Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical Relevance88
Carbon Dots as Promising Tools for Cancer Diagnosis and Therapy88
Recent Development of Gold Nanoparticles as Contrast Agents for Cancer Diagnosis87
Sulforaphane: A Broccoli Bioactive Phytocompound with Cancer Preventive Potential87
FAP and FAPI-PET/CT in Malignant and Non-Malignant Diseases: A Perfect Symbiosis?87
CAR-T: What Is Next?87
Immunomodulatory Effects of IL-2 and IL-15; Implications for Cancer Immunotherapy86
Tumor Mutational Burden as a Potential Biomarker for Immunotherapy in Pancreatic Cancer: Systematic Review and Still-Open Questions86
Tumor Microenvironment in Breast Cancer—Updates on Therapeutic Implications and Pathologic Assessment85
The TCGA Molecular Classification of Endometrial Cancer and Its Possible Impact on Adjuvant Treatment Decisions85
The New Era of Immunotherapy in Gastric Cancer84
Tumor Heterogeneity: A Great Barrier in the Age of Cancer Immunotherapy83
FGFR Inhibitors in Oncology: Insight on the Management of Toxicities in Clinical Practice83
Perspectives on the Role of Isoliquiritigenin in Cancer82
Targeted Therapy in Advanced and Metastatic Non-Small Cell Lung Cancer. An Update on Treatment of the Most Important Actionable Oncogenic Driver Alterations82
Therapeutic Potential of Certain Terpenoids as Anticancer Agents: A Scoping Review82
Dual Effect of Immune Cells within Tumour Microenvironment: Pro- and Anti-Tumour Effects and Their Triggers81
Adolescent and Young Adult (AYA) Cancer Survivorship Practices: An Overview81
Trastuzumab Mechanism of Action; 20 Years of Research to Unravel a Dilemma80
Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on Disease Development/Progression, and Potential as Therapeutic Targets80
A Systematic Review of Glioblastoma-Targeted Therapies in Phases II, III, IV Clinical Trials80
The miR-200 Family of microRNAs: Fine Tuners of Epithelial-Mesenchymal Transition and Circulating Cancer Biomarkers80
Recent Advances and Future Directions in Clinical Management of Head and Neck Squamous Cell Carcinoma80
Overcoming Challenges for CD3-Bispecific Antibody Therapy in Solid Tumors78
Plasma-Treated Solutions (PTS) in Cancer Therapy78
The Colorectal Cancer Tumor Microenvironment and Its Impact on Liver and Lung Metastasis78
Microtubule Targeting Agents in Disease: Classic Drugs, Novel Roles78
Drug Combination in Cancer Treatment—From Cocktails to Conjugated Combinations78
Pathology and Classification of SCLC78
Prognostic Significance of CD4+ and CD8+ Tumor-Infiltrating Lymphocytes in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis77
Microwave Ablation Versus Radiofrequency Ablation for Treatment of Hepatocellular Carcinoma: A Meta-Analysis of Randomized Controlled Trials77
Tumor Cell Infiltration into the Brain in Glioblastoma: From Mechanisms to Clinical Perspectives77
Mechanisms of Resistance to Conventional Therapies for Osteosarcoma77
New Angiogenic Regulators Produced by TAMs: Perspective for Targeting Tumor Angiogenesis76
Nanotechnology and Nanocarrier-Based Drug Delivery as the Potential Therapeutic Strategy for Glioblastoma Multiforme: An Update76
A Comprehensive Review on Solitary Fibrous Tumor: New Insights for New Horizons76
Impact of Proton Pump Inhibitors and Histamine-2-Receptor Antagonists on Non-Small Cell Lung Cancer Immunotherapy: A Systematic Review and Meta-Analysis76
The Role of Antigen Processing and Presentation in Cancer and the Efficacy of Immune Checkpoint Inhibitor Immunotherapy76
Cancer-Associated Angiogenesis: The Endothelial Cell as a Checkpoint for Immunological Patrolling75
Hypoxia-Induced Cancer Cell Responses Driving Radioresistance of Hypoxic Tumors: Approaches to Targeting and Radiosensitizing75
MicroRNAs in the Pathogenesis of Hepatocellular Carcinoma: A Review75
Oncolytic Viruses: Newest Frontier for Cancer Immunotherapy74
Senolytics for Cancer Therapy: Is All that Glitters Really Gold?74
BRCA Mutations in Ovarian and Prostate Cancer: Bench to Bedside74
Combined CDK2 and CDK4/6 Inhibition Overcomes Palbociclib Resistance in Breast Cancer by Enhancing Senescence74
Novel HER2-Directed Treatments in Advanced Gastric Carcinoma: AnotHER Paradigm Shift?74
The Flt3L/Flt3 Axis in Dendritic Cell Biology and Cancer Immunotherapy73
Extracellular Matrices and Cancer-Associated Fibroblasts: Targets for Cancer Diagnosis and Therapy?73
Timely Palliative Care: Personalizing the Process of Referral73
Malignant Ascites in Ovarian Cancer: Cellular, Acellular, and Biophysical Determinants of Molecular Characteristics and Therapy Response73
Trends in Research on Exosomes in Cancer Progression and Anticancer Therapy72
The Current Status of Photodynamic Therapy in Cancer Treatment72
Non-Coding RNAs as Mediators of Epigenetic Changes in Malignancies72
Urine as a Source of Liquid Biopsy for Cancer72
The Anti-VEGF(R) Drug Discovery Legacy: Improving Attrition Rates by Breaking the Vicious Cycle of Angiogenesis in Cancer71
Mechanisms of ADC Toxicity and Strategies to Increase ADC Tolerability71
The Tumor Microenvironment in Tumorigenesis and Therapy Resistance Revisited70
Aberrant Sialylation in Cancer: Biomarker and Potential Target for Therapeutic Intervention?70
Lung Adenocarcinoma Tumor Origin: A Guide for Personalized Medicine70
Immunotherapy in Melanoma: Recent Advances and Future Directions70
Trop2: Jack of All Trades, Master of None69
The Role of Chronic Inflammation in the Development of Breast Cancer69
The Role and Therapeutic Targeting of JAK/STAT Signaling in Glioblastoma69
Automated Detection and Classification of Oral Lesions Using Deep Learning to Detect Oral Potentially Malignant Disorders69
LAG-3 Blockade with Relatlimab (BMS-986016) Restores Anti-Leukemic Responses in Chronic Lymphocytic Leukemia69
Current Status and Future Prospects for Esophageal Cancer69
Cell-Free DNA–Based Multi-Cancer Early Detection Test in an Asymptomatic Screening Population (NHS-Galleri): Design of a Pragmatic, Prospective Randomised Controlled Trial69
Matrix Stiffness Contributes to Cancer Progression by Regulating Transcription Factors69
Cardiac Toxicity Associated with Immune Checkpoint Inhibitors: A Systematic Review69
Is Emodin with Anticancer Effects Completely Innocent? Two Sides of the Coin69
Tumor-Associated Macrophages in Hepatocellular Carcinoma Pathogenesis, Prognosis and Therapy68
O-GlcNAcylation and O-GlcNAc Cycling Regulate Gene Transcription: Emerging Roles in Cancer68
Cancer Extracellular Matrix Proteins Regulate Tumour Immunity68
Breast Cancer Stem Cells: Biomarkers, Identification and Isolation Methods, Regulating Mechanisms, Cellular Origin, and Beyond68
Tumor-Associated Neutrophils in Hepatocellular Carcinoma Pathogenesis, Prognosis, and Therapy68
Characteristics of the Tumor Microenvironment That Influence Immune Cell Functions: Hypoxia, Oxidative Stress, Metabolic Alterations68
The Potential of Lonidamine in Combination with Chemotherapy and Physical Therapy in Cancer Treatment68
The Association between the Pan-Immune-Inflammation Value and Cancer Prognosis: A Systematic Review and Meta-Analysis67
Recent Advances in Exosome-Based Drug Delivery for Cancer Therapy67
Prognostic Value of HER2-Low Expression in Non-Metastatic Triple-Negative Breast Cancer and Correlation with Other Biomarkers67
Brain Tumor Detection Based on Deep Learning Approaches and Magnetic Resonance Imaging66
Current Progresses and Challenges of Immunotherapy in Triple-Negative Breast Cancer66
Magnetic Nanoparticles—A Multifunctional Potential Agent for Diagnosis and Therapy66
Functional Interaction among lncRNA HOTAIR and MicroRNAs in Cancer and Other Human Diseases66
ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers66
Targeting CDK9 for Anti-Cancer Therapeutics66
Pancreatic Cancer and Immunotherapy: A Clinical Overview66
The Current Landscape of NKT Cell Immunotherapy and the Hills Ahead66
Targeted Delivery Methods for Anticancer Drugs65
The Impact of Estrogens and Their Receptors on Immunity and Inflammation during Infection65
Brain Metastases in HER2-Positive Breast Cancer: Current and Novel Treatment Strategies65
Soluble Programmed Death Ligand-1 (sPD-L1): A Pool of Circulating Proteins Implicated in Health and Diseases65
Collagen Type XI Alpha 1 (COL11A1): A Novel Biomarker and a Key Player in Cancer65
Claudins and Gastric Cancer: An Overview64
Papillary Thyroid Cancer Prognosis: An Evolving Field64
Cytotoxic T-Lymphocyte Antigen-4 in Colorectal Cancer: Another Therapeutic Side of Capecitabine64
Drug Resistance in Osteosarcoma: Emerging Biomarkers, Therapeutic Targets and Treatment Strategies64
Nanotechnology in Bladder Cancer: Diagnosis and Treatment63
Plasmin and Plasminogen System in the Tumor Microenvironment: Implications for Cancer Diagnosis, Prognosis, and Therapy63
Type I and II Interferons in the Anti-Tumor Immune Response63
Adoptive Immunotherapy beyond CAR T-Cells63
The Pan-Immune-Inflammation-Value Predicts the Survival of Patients with Human Epidermal Growth Factor Receptor 2 (HER2)—Positive Advanced Breast Cancer Treated with First-Line Taxane-Trastuzumab-Pert63
Primary and Acquired Resistance to Immunotherapy in Lung Cancer: Unveiling the Mechanisms Underlying of Immune Checkpoint Blockade Therapy62
DSCC_Net: Multi-Classification Deep Learning Models for Diagnosing of Skin Cancer Using Dermoscopic Images62
FET PET Radiomics for Differentiating Pseudoprogression from Early Tumor Progression in Glioma Patients Post-Chemoradiation62
Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma62
Mechanical Aspects of Angiogenesis62
Anaplastic Thyroid Carcinoma: An Update62
CCR4 as a Therapeutic Target for Cancer Immunotherapy62
Microfluidic Organoids-on-a-Chip: Quantum Leap in Cancer Research62
Gynecological Cancers Caused by Deficient Mismatch Repair and Microsatellite Instability61
Dissecting Tumor Growth: The Role of Cancer Stem Cells in Drug Resistance and Recurrence61
Boosted EfficientNet: Detection of Lymph Node Metastases in Breast Cancer Using Convolutional Neural Networks61
Agonistic CD40 Antibodies in Cancer Treatment61
Role of Artificial Intelligence in the Early Diagnosis of Oral Cancer. A Scoping Review61
Tumor-Associated Microglia and Macrophages in the Glioblastoma Microenvironment and Their Implications for Therapy61
Key Matrix Remodeling Enzymes: Functions and Targeting in Cancer61
Classification of Breast Cancer Nottingham Prognostic Index Using High-Dimensional Embedding and Residual Neural Network60
Current Surgical Management of Peri-Hilar and Intra-Hepatic Cholangiocarcinoma60
The m6A RNA Demethylase ALKBH5 Promotes Radioresistance and Invasion Capability of Glioma Stem Cells60
Comparison of FLASH Proton Entrance and the Spread-Out Bragg Peak Dose Regions in the Sparing of Mouse Intestinal Crypts and in a Pancreatic Tumor Model60
Diabetes and Cancer: Risk, Challenges, Management and Outcomes60
Metabolomics to Assess Response to Immune Checkpoint Inhibitors in Patients with Non-Small-Cell Lung Cancer60
CBP/p300: Critical Co-Activators for Nuclear Steroid Hormone Receptors and Emerging Therapeutic Targets in Prostate and Breast Cancers60
The Carcinogenic Effects of Formaldehyde Occupational Exposure: A Systematic Review60
Role of Artificial Intelligence in Radiogenomics for Cancers in the Era of Precision Medicine59
Photodynamic Therapy: Targeting Cancer Biomarkers for the Treatment of Cancers59
Response and Toxicity to Cytarabine Therapy in Leukemia and Lymphoma: From Dose Puzzle to Pharmacogenomic Biomarkers59
Flavonoids Targeting HIF-1: Implications on Cancer Metabolism59
Etiology of Acute Leukemia: A Review59
Lipid Metabolism in Oncology: Why It Matters, How to Research, and How to Treat59
Recent Insights into Therapy Resistance in Osteosarcoma59
Measles Virus as an Oncolytic Immunotherapy59
Targeted Oral Delivery of Paclitaxel Using Colostrum-Derived Exosomes59
Role of Methylation in Pro- and Anti-Cancer Immunity59
Liquid Biopsy in Prostate Cancer Management—Current Challenges and Future Perspectives58
Immune Checkpoint Inhibitors in Prostate Cancer58
Fighting Drug Resistance through the Targeting of Drug-Tolerant Persister Cells58
Radon and Lung Cancer: Current Trends and Future Perspectives58
HER2 Status in High-Risk Endometrial Cancers (PORTEC-3): Relationship with Histotype, Molecular Classification, and Clinical Outcomes58
Newcastle Disease Virus at the Forefront of Cancer Immunotherapy58
Molecular Mechanism of EGFR-TKI Resistance in EGFR-Mutated Non-Small Cell Lung Cancer: Application to Biological Diagnostic and Monitoring58
Prognostic Utility of Platelet–Lymphocyte Ratio, Neutrophil–Lymphocyte Ratio and Monocyte–Lymphocyte Ratio in Head and Neck Cancers: A Detailed PRISMA Compliant Systematic Review and Meta-Analysis58
Novel Insights on the Use of L-Asparaginase as an Efficient and Safe Anti-Cancer Therapy58
Cancer Therapeutic Targeting of Hypoxia Induced Carbonic Anhydrase IX: From Bench to Bedside58
Precision Medicine: Disease Subtyping and Tailored Treatment57
Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler57
Curcumin: Modulator of Key Molecular Signaling Pathways in Hormone-Independent Breast Cancer57
Review of the Geant4-DNA Simulation Toolkit for Radiobiological Applications at the Cellular and DNA Level57
miRNAs and lncRNAs as Novel Therapeutic Targets to Improve Cancer Immunotherapy57
Homology-Based Image Processing for Automatic Classification of Histopathological Images of Lung Tissue57
The Role of Hypoxia in Glioblastoma Radiotherapy Resistance57
Oncogenic Effects of HIV-1 Proteins, Mechanisms Behind56
Feedforward Artificial Neural Network-Based Colorectal Cancer Detection Using Hyperspectral Imaging: A Step towards Automatic Optical Biopsy56
Recruitment and Expansion of Tregs Cells in the Tumor Environment—How to Target Them?56
Tumor Infiltrating Lymphocyte (TIL) Therapy for Solid Tumor Treatment: Progressions and Challenges55
Accelerated T2-Weighted TSE Imaging of the Prostate Using Deep Learning Image Reconstruction: A Prospective Comparison with Standard T2-Weighted TSE Imaging55
Cold Atmospheric Plasma: A Promising Controller of Cancer Cell States55
Deep Learning Techniques to Diagnose Lung Cancer55
Survival Outcomes and Prognostic Factors in Glioblastoma55
The Role of p53 Dysfunction in Colorectal Cancer and Its Implication for Therapy55
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