OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Flow Chemistry is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Scalability of photochemical reactions in continuous flow mode	95
Flow chemistry for process optimisation using design of experiments	36
Reactor design and selection for effective continuous manufacturing of pharmaceuticals	27
Bulk Nanobubbles: generation using a two-chamber swirling flow nozzle and long-term stability in water	17
Continuous hydrogenation of halogenated nitroaromatic compounds in a micropacked bed reactor	16
Continuous citrate‐capped gold nanoparticle synthesis in a two‐phase flow reactor	16
3D printed ceramics as solid supports for enzyme immobilization: an automated DoE approach for applications in continuous flow	16
Continuous nitration of o-dichlorobenzene in micropacked-bed reactor: process design and modelling	14
Performance study and comparison between catalytic static mixer and packed bed in heterogeneous hydrogenation of vinyl acetate	13
High-pressure asymmetric hydrogenation in a customized flow reactor and its application in multi-step flow synthesis of chiral drugs	11
Discrimination of ablation, shielding, and interface layer effects on the steady-state formation of persistent bubbles under liquid flow conditions during laser synthesis of colloids	10
Scaled up and telescoped synthesis of propofol under continuous-flow conditions	10
Electrosynthesis of 3,3′,5,5’-Tetramethyl-2,2′-biphenol in Flow	10
Synthesis of new heterocyclic resveratrol analogues in milli- and microreactors: intensification of the Wittig reaction	10
Flow field designs developed by comprehensive CFD model decrease system costs of vanadium redox-flow batteries	10
A continuous flow bromodimethylsulfonium bromide generator: application to the synthesis of 2-arylaziridines from styrenes	10
Simultaneous self-optimisation of yield and purity through successive combination of inline FT-IR spectroscopy and online mass spectrometry in flow reactions	9
Rational design of the inlet configuration of flow systems for enhanced mixing	9
Continuous milli-scale reaction calorimeter for direct scale-up of flow chemistry	9
Software-guided microscale flow calorimeter for efficient acquisition of thermokinetic data	9
Continuous synthesis of copper nanoparticles using a polyol process in a milli-channel reactor	8
Gas-liquid mass transfer intensification for bubble generation and breakup in micronozzles	8
Innovative continuous synthesis of solketal	8
Continuous synthesis of monodisperse silica microspheres over 1 μm size	8
Extending practical flow chemistry into the undergraduate curriculum via the use of a portable low-cost 3D printed continuous flow system	7

Hydrogenation of nitroarenes in continuous flow with TPP/Raney Ni	7
Continuous flow synthesis of xylidines via biphasic nitration of xylenes and nitro-reduction	7
Continuous Flow Generation of Highly Reactive Organometallic Intermediates: A Recent Update	7
Controllable preparation of double emulsion droplets in a dual-coaxial microfluidic device	7
Mathematical model of gas-liquid or liquid-liquid Taylor flow with non-Newtonian continuous liquid in microchannels	7
Imposed dynamic irradiation to intensify photocatalytic reactions	7
Effect of residence time on the morphology of silica nanoparticles synthesized in a microfluidic reactor	7
Complete chiral resolution in a continuous flow crystallizer with recycle stream	7
One-flow synthesis of tetrahydrocannabinol and cannabidiol using homo- and heterogeneous Lewis acids	6
Continuous heterogeneous synthesis of hexafluoroacetone and its machine learning-assisted optimization	6
Analytical-scale synthesis of aryl-SF4Cl via flow microfluidic technology	6
Slug flow as tool for selectivity control in the homogeneously catalysed solvent-free epoxidation of methyl oleate	6
5-Hydroxymethylfurfural synthesis from fructose over deep eutectic solvents in batch reactors and continuous flow microreactors	6
Open-source multi-purpose sensor for measurements in continuous capillary flow	6
Optimization of a 3D-printed tubular reactor for free radical polymerization by CFD	6
Continuous flow organocatalyzed methoxycarbonylation of benzyl alcohol derivatives with dimethyl carbonate	6
Continuous flow synthesis of Celecoxib from 2-bromo-3,3,3-trifluoropropene	6
A revised 1D equivalent model for the determination of incident photon flux density in a continuous-flow LED-driven spiral-shaped microreactor using the actinometry method with Reinecke’s salt	6
Delineating a green, catalyst free synthesis of a popular nutraceutical methylsulfonylmethane (MSM) in continuous flow	6
Continuous-flow RAFT copolymerization of styrene and maleic anhydride: acceleration of reaction and effect of polymerization conditions on reaction kinetics	6
3D printed reactors and Kessil lamp holders for flow photochemistry: design and system standardization	5
Sucrose solution as a new viscous test fluid with tunable viscosities up to 2 Pas for micromixing characterization by the Villermaux–Dushman reaction	5
3D-printed device for synthesis of magnetic and metallic nanoparticles	5
Advances in continuous polymer analysis in flow with application towards biopolymers	5
Process design of two-step mononitration of m-xylene in a microreactor	5
TfOH-catalyzed three-component synthesis of Dithiocarbamates from α-Diazoesters under continuous flow conditions	5
Practical and rapid construction of 2-pyridyl ketone library in continuous flow	4
Leveraging first-principles and empirical models for disturbance detection in continuous pharmaceutical syntheses	4
Micro-Batch flow reactor for the photoproduction of H2O2 from water/real seawater	4
Synthesis of flow‐compatible Ru-Me/Al2O3 catalysts and their application in hydrogenation of 1-iodo-4-nitrobenzene	4
Bubbles size and mass transfer in a pulsating flow type apparatus with gas-liquid mixture	4
Continuous-flow synthesis of N,N′-bis(2,2,6,6-tetramethyl-4-piperidinyl)-1,6-hexanediamine (DTMPA) in a Micro fixed-bed reactor	4
3D investigations of microscale mixing in helically coiled capillaries	4
FOMSy: 3D-printed flexible open-source microfluidic system and flow synthesis of PET-tracer	4
Ion mobility spectrometry-tandem mass spectrometry strategies for the on-line monitoring of a continuous microflow reaction	4
Continuous flow synthesis of HMF from glucose using gadolinium (III) trifluoromethanesulfonate in Brønsted acidic ionic liquid as a catalytic system	4
Improving the reaction efficiency of condensation amidation of piperazine with benzoic acid based on kinetics study in microreactors	4
Photoreduction synthesis of various azoxybenzenes by visible-light irradiation under continuous flow conditions	4
Continuous synthesis of bromoalkyl glycosides by Fischer glycosylation in a microreactor	4
Kinetic analysis of the partial synthesis of artemisinin: Photooxygenation to the intermediate hydroperoxide	4
Nucleation in continuous flow cooling sonocrystallization for coiled capillary crystallizers	3
The applications of organozinc reagents in continuous flow chemistry: Negishi coupling	3
Inline monitoring of high ammonia concentrations in methanol with a customized 3D printed flow cell	3
A perspective on automated advanced continuous flow manufacturing units for the upgrading of biobased chemicals toward pharmaceuticals	3
Chemoselective borylation of bromoiodoarene in continuous flow: synthesis of bromoarylboronic acids	3
Continuous flow Friedel–Crafts acetylation of phenols and electron-rich arenes and heteroarenes	3
Advances in cofactor immobilization for enhanced continuous-flow biocatalysis	3
Simultaneous determination of enthalpy of mixing and reaction using milli-scale continuous flow calorimetry	3
Achieving selectivity in porphyrin bromination through a DoE-driven optimization under continuous flow conditions	3
Scale-out production in core-annular liquid–liquid microextractor	3

Lab-scale flow chemistry? Just do it yourself!	3
Accurate determination of the kinetics of toluene nitration in a liquid–liquid microflow system	3
Simultaneous production of hydrogen and acrylonitrile in a new bifunctional micro-reactor, mathematical modeling and optimization study	3
Rapid plugged flow synthesis of nucleoside analogues via Suzuki-Miyaura coupling and heck Alkenylation of 5-Iodo-2’-deoxyuridine (or cytidine)	3
Flow dearomatization of electron-poor 3-fluoromethylthioindoles by 1,3-dipolar cycloaddition	3
Kinetics and safeties of 2-Ethyl-1-hexanol nitration in a capillary-microreactor	3
A tri-fluid tortuous microfluidic chip for green synthesis of nanoparticles and inactivation of a model gram-negative bacteria: Intracellular components evaluation	3
A multi-step continuous flow synthesis of pomalidomide	3
Development of an automated flow chemistry affinity-based purification process for DNA-encoded chemistry	3
The joint effort of enzyme technology and flow chemistry to bring biocatalytic processes to the next level of sustainability, efficiency and productivity	3
Magnet-actuated microfluidic reactors with controllable Fe-based amorphous microspheres for tetracycline degradation	2
CFD analysis of asymmetric mixing at different inlet configurations of a split-and-recombine micro mixer	2
Multivariate curve resolution for kinetic modeling and scale-up prediction	2
Enzymatic kinetic resolution in flow for chiral mandelic acids	2
Impact of gas-solid direct contact on gas-liquid-solid reaction performance in a flow reactor	2
Development of a continuous flow process for the synthesis of mesotrione	2
Lithium aluminum hydride in flow: overcoming exotherms, solids, and gas evolution en route to chemoselective reductions	2
The continuous flow synthesis of azos	2
Enhancing N-arylation productivity: the amplified potential of electrophotocatalysis in flow	2
Selective monosubstitution on a trichlorosilane with highly reactive organolithium compounds in a microflow reactor	2
Voltage-driven microfluidic synthesis of magnetite and gold nanomaterials	2
Rapid prototyping of a modular optical flow cell for image-based droplet size measurements in emulsification processes	2
Design and scale-up of continuous di-nitration reaction using pinched tube flow reactor	2
Future medicinal chemists experience flow chemistry: optimization by experimental design of the limiting synthetic step to the antifungal drug econazole nitrate	2
Aerobic oxidation of hydroxymethylfurfural using a homogeneous TEMPO/TBN catalytic system in 3D-printed milli-scale porous reactors	2
Editorial special issue in the journal of flow chemistry: engineering aspects of flow chemistry	2
Minireview: recent efforts toward upgrading lignin-derived phenols in continuous flow	2
Investigating the effect of nonionic surfactant on the silica nanoparticles formation and morphology in a microfluidic reactor	2
Catalytic ketonization of propionic acid. Green chemistry in practice	2
Continuous flow synthesis of phenyl glucosazone and its conversion to 2H-1,2,3-Triazole building blocks	2
Telescoped synthesis of vicinal diamines via ring-opening of electrochemically generated aziridines in flow	2
3D-printed open-source sensor flow cells for microfluidic temperature, electrical conductivity, and pH value determination	2
Continuous flow ozonolysis of cardanol for greener synthesis of bio-based monomers	2
Challenges in transfer of gas-liquid reactions from batch to continuous operation: dimensional analysis and simulations for aerobic oxidation	2
Continuous flow reduction of 4-nitrophenol by “water soluble” palladium nanoparticles: from batch to continuous flow system	2