OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Flow Chemistry is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Continuous flow process development for the synthesis of an industrial raw material via solvent-free aromatic Claisen rearrangement	34
Solid dosing in High-Throughput Experimentation: generalization of mass enhancer technologies for submilligram scale	24
Synthesis of new heterocyclic resveratrol analogues in milli- and microreactors: intensification of the Wittig reaction	22
Multistep non-fouling continuous flow synthesis and PEG-functionalisation of biocompatible iron oxide nanoparticles for magnetic hyperthermia, photothermal heating and antifungal activity	19
FOMSy: 3D-printed flexible open-source microfluidic system and flow synthesis of PET-tracer	19
Determination of micromixing times in commercially available continuous-flow mixers: evaluation of the incorporation and interaction by exchange with the mean model	18
Magnet-actuated microfluidic reactors with controllable Fe-based amorphous microspheres for tetracycline degradation	18
Continuous flow Friedel–Crafts acetylation of phenols and electron-rich arenes and heteroarenes	15
Continuous synthesis of ε-caprolactone in a microreactor and kinetics insights into its side reactions	15
Correction: Seeded-growth synthesis of 20–60 nm monodisperse citrate-capped gold nanoparticles in a millifluidic reactor	14
Tandem continuous-flow α-C-H functionalization of pyrrolidine with aryl bromide-derived organolithium reagents	13
Seeded-growth synthesis of 20–60 nm monodisperse citrate-capped gold nanoparticles in a millifluidic reactor	13
Application of stop-flow micro-tubing reactor system in organic reaction development	12
Kinetics and safeties of 2-Ethyl-1-hexanol nitration in a capillary-microreactor	11
Expedited access to β-lactams via a telescoped three-component Staudinger reaction in flow	11
Continuous flow synthesis of HMF from glucose using gadolinium (III) trifluoromethanesulfonate in Brønsted acidic ionic liquid as a catalytic system	10
Telescoped synthesis of vicinal diamines via ring-opening of electrochemically generated aziridines in flow	10
Correction to: The applications of organozinc reagents in continuous flow chemistry: Negishi coupling	9
Continuous one-pot synthesis of new spiro-fused indoles from biobased building blocks using carbamoylation and imidation reactions under ultrasonic irradiation	9
Two deep learning methods in comparison to characterize droplet sizes in emulsification flow processes	9
Extraction and mass transfer of glyoxylic acid in a capillary microchannel	9
Continuous flow synthesis of phenyl glucosazone and its conversion to 2H-1,2,3-Triazole building blocks	8
Asymmetric electrochemical synthesis in flow	8
Safe and on-demand protocol for the continuous generation of SO2 and Cl2 for subsequent utilization in organic synthesis	8
Electrochemical telescoped synthesis of alkyl pinacol boranes	8

Straightforward, scalable, solution-phase synthesis of peptide bonds in flow	7
A tri-fluid tortuous microfluidic chip for green synthesis of nanoparticles and inactivation of a model gram-negative bacteria: Intracellular components evaluation	7
Electrophilic cyclization of reticuline-type alkaloids in flow via o-quinol intermediates	7
Continuous preparation and reaction of nonaflyl azide (NfN3) for the synthesis of organic azides and 1,2,3-triazoles	7
Microwave assisted flow synthesis of Ir-IrOx electrocatalysts for acidic oxygen evolution reaction: synthesis conditions and electrocatalytic performance correlation	7
Design and implementation of an automated DT-PhotoFluor radiosynthesis module for 18F-fluorination of aliphatic, branched chain amino acids	7
Accurate determination of the kinetics of toluene nitration in a liquid–liquid microflow system	7
Continuous dehydration of glycerol to Acrolein based on HPW/TS-COOH catalyzation	7
Selective synthesis of phenylhydroxylamine under slug flow conditions using Bayesian optimization	6
Overcoming the Achilles Heel of flow chemistry: strategies for solid handling in heterogeneous continuous-flow reactors	6
Continuous synthesis of benzaldehyde by ozonolysis of styrene in a micro-packed bed reactor	6
5-Hydroxymethylfurfural synthesis from fructose over deep eutectic solvents in batch reactors and continuous flow microreactors	6
Generation of styrene droplets in a coaxial flow device	6
Rapid prototyping of a modular optical flow cell for image-based droplet size measurements in emulsification processes	5
Practical synthesis of tetrahydrofolate by highly efficient catalytic hydrogenation in continuous flow	5
Emerging Investigators in Flow Chemistry 2023	5
Continuous-flow synthesis of prenyl chloride on-demand through surface-mediated hydrochlorination	5
Comparative economic analysis of batch vs. continuous manufacturing in catalytic heterogeneous processes: impact of catalyst activity maintenance and materials costs on total costs of manufacturing in	5
Functionalization of unsaturated carbon–carbon bonds by continuous-flow ozonolysis	5
Towards an approach to small-scale aryllithium flash flow chemistry using low-cost, low volume reactors	5
Correction to: Voltage-driven microfluidic synthesis of magnetite and gold nanomaterials	5
Effects of two-phase periodic velocity on droplet coalescence inside microchannels	5
Process design of two-step mononitration of m-xylene in a microreactor	5
Rapid plugged flow synthesis of nucleoside analogues via Suzuki-Miyaura coupling and heck Alkenylation of 5-Iodo-2’-deoxyuridine (or cytidine)	5
Continuous preparation of a nickel-based catalyst via membrane dispersion microreactor and its application in the hydrogenation of 4,4’-dinitrodiphenyl ether	5
Efficient “One-Column” grignard generation and reaction in continuous flow	5
Selective monosubstitution on a trichlorosilane with highly reactive organolithium compounds in a microflow reactor	4
Mediated formic acid flow fuel cell (MFAFFC) based on biomimetic electrolytes	4
Correction to: Continuous diameter increase reactor – a reactor concept for maximizing productivity by a controlled diameter extension	4
Synthesis of BuNENA in a continuous flow microreactor	4
Development of an automated flow chemistry affinity-based purification process for DNA-encoded chemistry	4
Driving sustainability through adoption of hybrid manufacturing in small molecule API production	4
Continuous stirred-tank degradation of persistent dyes via recycled iron/periodate oxidation system: process optimization	4
High-temperature S–S, S–O, and S–C bond transfer hydrogenolysis by lower alcohols in continuous flow mode	3
Best practice approach for temperature measurement in flow chemistry based on CFD simulation	3
A fully continuous-flow process for the synthesis of 4-nitropyrazole	3
Flow platform for the synthesis of benzodiazepines	3
On the design of a flexible, accessible photoreactor to pilot flow photochemistry experiments	3
Facile microfluidic device for droplets emulsion from small samples	3
Investigation into a high-p,T,c continuous flow synthesis of myristyl-γ-picolinium chloride (MGPC) – a preservative in pharmaceutical formulations	3
Editorial	3
Correction to: Synthesis of 2,3,5-trimethylbenzoquinone from 2,3,6-trimethylphenol and tert-butyl hydroperoxide in microreactors	3
An eco-friendly and very low catalyst loading continuous condensation of primary amines and 1,3 Di carbonyl compounds: Synthesis of enaminones and enaminoesters by microreactor technology	3
Development of continuous flow photochemistry-based protocol for the synthesis of Sulindac related impurity	3
Process intensification toward galanthamine: continuous flow N-methylation of demethylbromonarwedine	3
Continuous flow ozonolysis of cardanol for greener synthesis of bio-based monomers	3
Investigations on the continuous flow generation of 2,6-dichloro-N-fluoropyridinium tetrafluoroborate using F2 gas	3
Formation of double emulsion droplets in flow-focusing microchips: a numerical parametric study	3
Micro-Batch flow reactor for the photoproduction of H2O2 from water/real seawater	3
Correction to: Continuous Flow Process for Preparing Budesonide	2

Microfluidic synthesis of LaF3:Ce,Tb core-shell nanoparticles: effects of synthesis parameters on morphology and size	2
Bringing flow chemistry to the teaching laboratory: an air fryer as heater in simple flow chemistry esterifications	2
HO-SAS catalyzed protection and deprotection of aldehydes and alcohols in continuous flow reactors	2
The continuous flow synthesis of azos	2
Enhancing N-arylation productivity: the amplified potential of electrophotocatalysis in flow	2
Two photons are better than one: continuous flow synthesis of ꞵ-lactones through a doubly photochemically-activated Paternò-Büchi reaction	2
Efficient pinnick oxidation by a superheated micro-reaction process	2
Nitration process of 2-(2,4-dichlorophenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one in a microreactor	2
Continuous flow synthesis of (E)-O-(3-chloro-2-propenyl)hydroxylamine: a key intermediate of clethodim	2
Recent developments of automated flow chemistry in pharmaceutical compounds synthesis	2
Methyl acetate production by reactive distillation using a vertical plate microdistillator	2
Continuous heterogeneous synthesis of hexafluoroacetone and its machine learning-assisted optimization	2
A three-dimensional model of a packed bed reactor with resolved pore space - an example of ammonia synthesis and its improvements	2
Multivariate curve resolution for kinetic modeling and scale-up prediction	2
Continuous flow synthesis of meso-substituted porphyrins with inline UV–Vis analysis	2
Continuous Flow Generation of Highly Reactive Organometallic Intermediates: A Recent Update	2
Novel insights into acetylation kinetics in a continuous Flow milli-reactor for chemo-enzymatic separation of silybin A/B	2