OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Flow Chemistry is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Control of mixing in a continuous-flow microreactor with an integrated bubble	107
Gas-liquid mass transfer intensification for bubble generation and breakup in micronozzles	38
Asymmetric electrochemical synthesis in flow	19
Scalable synthesis of selective hydrodeoxygenation inverted Pd@TiO2 nanocatalysts	19
Continuous milli-scale reaction calorimeter for direct scale-up of flow chemistry	19
Organic–inorganic hybrid electro-optic material with Disperse Red 1 chromophore fabricated by flow chemistry	19
Continuous flow process optimization aided by machine learning for a pharmaceutical intermediate	14
Practical synthesis of tetrahydrofolate by highly efficient catalytic hydrogenation in continuous flow	12
Leveraging flow chemistry for the synthesis of trisubstituted isoxazoles	12
Continuous flow process development for the synthesis of an industrial raw material via solvent-free aromatic Claisen rearrangement	11
Safe and on-demand protocol for the continuous generation of SO2 and Cl2 for subsequent utilization in organic synthesis	11
A perspective on the past, the present, and the future of computational fluid dynamics (CFD) in flow chemistry	10
Solid dosing in High-Throughput Experimentation: generalization of mass enhancer technologies for submilligram scale	10
Advances in continuous polymer analysis in flow with application towards biopolymers	10
Photoreduction synthesis of various azoxybenzenes by visible-light irradiation under continuous flow conditions	10
The synthesis of Aspirin and Acetobromo-α-D-glucose using 3D printed flow reactors: an undergraduate demonstration	10
Rapid plugged flow synthesis of nucleoside analogues via Suzuki-Miyaura coupling and heck Alkenylation of 5-Iodo-2’-deoxyuridine (or cytidine)	9
Leveraging first-principles and empirical models for disturbance detection in continuous pharmaceutical syntheses	9
Continuous flow synthesis of phenyl glucosazone and its conversion to 2H-1,2,3-Triazole building blocks	9
Dominance of heat transfer limitations in conventional sol-gel synthesis of LTA revealed by microcrystallization	8
Synthesis of new heterocyclic resveratrol analogues in milli- and microreactors: intensification of the Wittig reaction	8
An eco-friendly and very low catalyst loading continuous condensation of primary amines and 1,3 Di carbonyl compounds: Synthesis of enaminones and enaminoesters by microreactor technology	8
Voltage-driven microfluidic synthesis of magnetite and gold nanomaterials	8
Access semi-stabilized and unstabilized diazo compounds using iodosylbenzene	8
Continuous one-pot synthesis of new spiro-fused indoles from biobased building blocks using carbamoylation and imidation reactions under ultrasonic irradiation	8

3D investigations of microscale mixing in helically coiled capillaries	7
Functionalization of unsaturated carbon–carbon bonds by continuous-flow ozonolysis	7
Continuous synthesis of N-(3-Amino-4-methylphenyl)benzamide and its kinetics study in microflow system	7
Metal-free catalyzed aerobic oxidation of 2-nitro-4-methylsulfone toluene to 2-nitro-4-methylsulfonylbenzoic acid using a continuous-flow reactor	7
Investigating the effect of a monovalent ion on the droplet’s size and distribution in a surfactant-free droplet generation microfluidic chip	7
Rapid prototyping of a modular optical flow cell for image-based droplet size measurements in emulsification processes	7
Scaled up and telescoped synthesis of propofol under continuous-flow conditions	6
CFD analysis of asymmetric mixing at different inlet configurations of a split-and-recombine micro mixer	6
Reactor design and selection for effective continuous manufacturing of pharmaceuticals	6
Continuous flow organocatalyzed methoxycarbonylation of benzyl alcohol derivatives with dimethyl carbonate	6
Micro-Batch flow reactor for the photoproduction of H2O2 from water/real seawater	6
Advances in cofactor immobilization for enhanced continuous-flow biocatalysis	6
The joint effort of enzyme technology and flow chemistry to bring biocatalytic processes to the next level of sustainability, efficiency and productivity	6
FOMSy: 3D-printed flexible open-source microfluidic system and flow synthesis of PET-tracer	6
Multivariate curve resolution for kinetic modeling and scale-up prediction	5
Meet the Flow Chemist – Dr. Anna G. Slater	5
Determination of micromixing times in commercially available continuous-flow mixers: evaluation of the incorporation and interaction by exchange with the mean model	5
Correction to: Continuous diameter increase reactor – a reactor concept for maximizing productivity by a controlled diameter extension	5
Continuous flow synthesis of (E)-O-(3-chloro-2-propenyl)hydroxylamine: a key intermediate of clethodim	5
Meet The Flow Chemist – Prof. Ryan L. Hartman	5
Application of natural deep eutectic solvents in the continuous process for synthesis of resveratrol analogues by the Wittig reaction	5
Selective monosubstitution on a trichlorosilane with highly reactive organolithium compounds in a microflow reactor	4
Continuous flow Friedel–Crafts acetylation of phenols and electron-rich arenes and heteroarenes	4
Diphenylmethyl deprotection in continuous flow and its application in synthesis of β-lactam antibiotics	4
Development of an automated flow chemistry affinity-based purification process for DNA-encoded chemistry	4
Correction to: FOMSy: 3D-printed flexible open-source microfluidic system and flow synthesis of PET-tracer	4
Sucrose solution as a new viscous test fluid with tunable viscosities up to 2 Pas for micromixing characterization by the Villermaux–Dushman reaction	4
Continuous dehydration of glycerol to Acrolein based on HPW/TS-COOH catalyzation	4
Continuous flow process for preparing budesonide	4
Development of a palladium-catalyzed decarboxylative arene cross-coupling of pyrrole derivatives in a flow reactor	4
Design and structural parameter optimization of Venturi-type microbubble reactor for wastewater treatment by CFD simulation	4
Nitration process of 2-(2,4-dichlorophenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one in a microreactor	4
Continuous-flow RAFT copolymerization of styrene and maleic anhydride: acceleration of reaction and effect of polymerization conditions on reaction kinetics	4
A modular flow process intensification towards lipid peptoids nano assembly formation	4
Continuous flow synthesis of the lamivudine precursor L-Menthyl Glyoxylate	4
Magnet-actuated microfluidic reactors with controllable Fe-based amorphous microspheres for tetracycline degradation	4
Continuous catalytic aerobic oxidation of o‑chlorotoluene to o-chlorobenzoic acid under slug flow conditions	4
HO-SAS catalyzed protection and deprotection of aldehydes and alcohols in continuous flow reactors	4
Efficient pinnick oxidation by a superheated micro-reaction process	4
Continuous preparation and reaction of nonaflyl azide (NfN3) for the synthesis of organic azides and 1,2,3-triazoles	3
Continuous-flow Synthesis of Anisotropic Plasmonic Nanostructures	3
Synthesis of BuNENA in a continuous flow microreactor	3
Challenges in transfer of gas-liquid reactions from batch to continuous operation: dimensional analysis and simulations for aerobic oxidation	3
Delineating a green, catalyst free synthesis of a popular nutraceutical methylsulfonylmethane (MSM) in continuous flow	3
Study of propane/air catalytic combustion in heat recirculating U-bend and spiral microcombustors	3
Lab-scale flow chemistry? Just do it yourself!	3
Driving sustainability through adoption of hybrid manufacturing in small molecule API production	3
Enhancing N-arylation productivity: the amplified potential of electrophotocatalysis in flow	3
Chemoselective borylation of bromoiodoarene in continuous flow: synthesis of bromoarylboronic acids	3
Optimization of a 3D-printed tubular reactor for free radical polymerization by CFD	3

Slug flow as tool for selectivity control in the homogeneously catalysed solvent-free epoxidation of methyl oleate	3
Imposed dynamic irradiation to intensify photocatalytic reactions	3
Simultaneous self-optimisation of yield and purity through successive combination of inline FT-IR spectroscopy and online mass spectrometry in flow reactions	3
The continuous flow synthesis of azos	3
Mediated formic acid flow fuel cell (MFAFFC) based on biomimetic electrolytes	3
Continuous morphology-controllable precipitation strategy for europium oxalate hydrates via microchannel reactor	3
Editorial special issue in the journal of flow chemistry: engineering aspects of flow chemistry	3
Continuous citrate‐capped gold nanoparticle synthesis in a two‐phase flow reactor	3
Continuous flow synthesis of meso-substituted porphyrins with inline UV–Vis analysis	3
Reactor performance estimation in microscale flow calorimeter for rapid characterization of exothermic reactions	2
Minireview: recent efforts toward upgrading lignin-derived phenols in continuous flow	2
A tri-fluid tortuous microfluidic chip for green synthesis of nanoparticles and inactivation of a model gram-negative bacteria: Intracellular components evaluation	2
Continuous Flow Generation of Highly Reactive Organometallic Intermediates: A Recent Update	2
Recent developments of automated flow chemistry in pharmaceutical compounds synthesis	2
Mathematical model of gas-liquid or liquid-liquid Taylor flow with non-Newtonian continuous liquid in microchannels	2
A multi-step continuous flow synthesis of pomalidomide	2
Accurate determination of the kinetics of toluene nitration in a liquid–liquid microflow system	2
Correction to: Meet the flow chemist – Prof. Norbert Kockmann	2
Continuous flow reduction of 4-nitrophenol by “water soluble” palladium nanoparticles: from batch to continuous flow system	2
Continuous synthesis of ε-caprolactone in a microreactor and kinetics insights into its side reactions	2
Lithium aluminum hydride in flow: overcoming exotherms, solids, and gas evolution en route to chemoselective reductions	2
Two photons are better than one: continuous flow synthesis of ꞵ-lactones through a doubly photochemically-activated Paternò-Büchi reaction	2
A perspective on automated advanced continuous flow manufacturing units for the upgrading of biobased chemicals toward pharmaceuticals	2
Seeded-growth synthesis of 20–60 nm monodisperse citrate-capped gold nanoparticles in a millifluidic reactor	2
3D printed reactors and Kessil lamp holders for flow photochemistry: design and system standardization	2