OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Flow Chemistry is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Synthesis of new heterocyclic resveratrol analogues in milli- and microreactors: intensification of the Wittig reaction	115
Continuous flow process development for the synthesis of an industrial raw material via solvent-free aromatic Claisen rearrangement	40
Solid dosing in High-Throughput Experimentation: generalization of mass enhancer technologies for submilligram scale	20
FOMSy: 3D-printed flexible open-source microfluidic system and flow synthesis of PET-tracer	19
Reactor design and selection for effective continuous manufacturing of pharmaceuticals	19
Determination of micromixing times in commercially available continuous-flow mixers: evaluation of the incorporation and interaction by exchange with the mean model	15
Continuous citrate‐capped gold nanoparticle synthesis in a two‐phase flow reactor	13
Continuous flow Friedel–Crafts acetylation of phenols and electron-rich arenes and heteroarenes	12
Magnet-actuated microfluidic reactors with controllable Fe-based amorphous microspheres for tetracycline degradation	12
Correction: Seeded-growth synthesis of 20–60 nm monodisperse citrate-capped gold nanoparticles in a millifluidic reactor	11
Application of stop-flow micro-tubing reactor system in organic reaction development	11
Seeded-growth synthesis of 20–60 nm monodisperse citrate-capped gold nanoparticles in a millifluidic reactor	11
Correction to: Meet the flow chemist – Prof. Norbert Kockmann	11
Continuous synthesis of ε-caprolactone in a microreactor and kinetics insights into its side reactions	11
Continuous synthesis of copper nanoparticles using a polyol process in a milli-channel reactor	10
Kinetics and safeties of 2-Ethyl-1-hexanol nitration in a capillary-microreactor	10
Continuous flow synthesis of HMF from glucose using gadolinium (III) trifluoromethanesulfonate in Brønsted acidic ionic liquid as a catalytic system	10
Expedited access to β-lactams via a telescoped three-component Staudinger reaction in flow	10
A revised 1D equivalent model for the determination of incident photon flux density in a continuous-flow LED-driven spiral-shaped microreactor using the actinometry method with Reinecke’s salt	9
Open-source multi-purpose sensor for measurements in continuous capillary flow	9
Extraction and mass transfer of glyoxylic acid in a capillary microchannel	8
Two deep learning methods in comparison to characterize droplet sizes in emulsification flow processes	8
Complete chiral resolution in a continuous flow crystallizer with recycle stream	8
Telescoped synthesis of vicinal diamines via ring-opening of electrochemically generated aziridines in flow	8
Kinetic analysis of the partial synthesis of artemisinin: Photooxygenation to the intermediate hydroperoxide	8

Meet The Flow Chemist – Alain George	8
CFD analysis of asymmetric mixing at different inlet configurations of a split-and-recombine micro mixer	7
Correction to: The applications of organozinc reagents in continuous flow chemistry: Negishi coupling	7
Continuous microflow synthesis of dimethyl-substituted cyclobutanetetracarboxylic dianhydrides and its application on polyimide films	7
Continuous one-pot synthesis of new spiro-fused indoles from biobased building blocks using carbamoylation and imidation reactions under ultrasonic irradiation	7
Design and scale-up of continuous di-nitration reaction using pinched tube flow reactor	7
Continuous milli-scale reaction calorimeter for direct scale-up of flow chemistry	6
Organic–inorganic hybrid electro-optic material with Disperse Red 1 chromophore fabricated by flow chemistry	6
Safe and on-demand protocol for the continuous generation of SO2 and Cl2 for subsequent utilization in organic synthesis	6
Continuous flow synthesis of phenyl glucosazone and its conversion to 2H-1,2,3-Triazole building blocks	6
Continuous dehydration of glycerol to Acrolein based on HPW/TS-COOH catalyzation	6
Asymmetric electrochemical synthesis in flow	6
Continuous flow organocatalyzed methoxycarbonylation of benzyl alcohol derivatives with dimethyl carbonate	6
Multistep batch-flow hybrid synthesis of a terbinafine precursor	5
Selective synthesis of phenylhydroxylamine under slug flow conditions using Bayesian optimization	5
Electrophilic cyclization of reticuline-type alkaloids in flow via o-quinol intermediates	5
Mathematical model of gas-liquid or liquid-liquid Taylor flow with non-Newtonian continuous liquid in microchannels	5
Accurate determination of the kinetics of toluene nitration in a liquid–liquid microflow system	5
Continuous synthesis of benzaldehyde by ozonolysis of styrene in a micro-packed bed reactor	5
5-Hydroxymethylfurfural synthesis from fructose over deep eutectic solvents in batch reactors and continuous flow microreactors	5
Continuous preparation and reaction of nonaflyl azide (NfN3) for the synthesis of organic azides and 1,2,3-triazoles	5
Design and implementation of an automated DT-PhotoFluor radiosynthesis module for 18F-fluorination of aliphatic, branched chain amino acids	5
Bulk Nanobubbles: generation using a two-chamber swirling flow nozzle and long-term stability in water	5
Effects of two-phase periodic velocity on droplet coalescence inside microchannels	5
Straightforward, scalable, solution-phase synthesis of peptide bonds in flow	5
A tri-fluid tortuous microfluidic chip for green synthesis of nanoparticles and inactivation of a model gram-negative bacteria: Intracellular components evaluation	5
Photoiodization of toluene in a microflow platform	4
Correction to: Voltage-driven microfluidic synthesis of magnetite and gold nanomaterials	4
Towards an approach to small-scale aryllithium flash flow chemistry using low-cost, low volume reactors	4
Rapid prototyping of a modular optical flow cell for image-based droplet size measurements in emulsification processes	4
Photoreduction synthesis of various azoxybenzenes by visible-light irradiation under continuous flow conditions	4
Comparative economic analysis of batch vs. continuous manufacturing in catalytic heterogeneous processes: impact of catalyst activity maintenance and materials costs on total costs of manufacturing in	4
Emerging Investigators in Flow Chemistry 2023	4
Rational design of the inlet configuration of flow systems for enhanced mixing	4
Functionalization of unsaturated carbon–carbon bonds by continuous-flow ozonolysis	4
Efficient “One-Column” grignard generation and reaction in continuous flow	4
Continuous-flow synthesis of prenyl chloride on-demand through surface-mediated hydrochlorination	4
Process design of two-step mononitration of m-xylene in a microreactor	4
Practical synthesis of tetrahydrofolate by highly efficient catalytic hydrogenation in continuous flow	4
Rapid plugged flow synthesis of nucleoside analogues via Suzuki-Miyaura coupling and heck Alkenylation of 5-Iodo-2’-deoxyuridine (or cytidine)	4
Development of an automated flow chemistry affinity-based purification process for DNA-encoded chemistry	3
Continuous flow ozonolysis of cardanol for greener synthesis of bio-based monomers	3
A fully continuous-flow process for the synthesis of 4-nitropyrazole	3
Correction to: Synthesis of 2,3,5-trimethylbenzoquinone from 2,3,6-trimethylphenol and tert-butyl hydroperoxide in microreactors	3
Driving sustainability through adoption of hybrid manufacturing in small molecule API production	3
Selective monosubstitution on a trichlorosilane with highly reactive organolithium compounds in a microflow reactor	3
Facile microfluidic device for droplets emulsion from small samples	3
Process intensification toward galanthamine: continuous flow N-methylation of demethylbromonarwedine	3
Best practice approach for temperature measurement in flow chemistry based on CFD simulation	3
Editorial	3

Lithium aluminum hydride in flow: overcoming exotherms, solids, and gas evolution en route to chemoselective reductions	3
Continuous flow synthesis of the lamivudine precursor L-Menthyl Glyoxylate	3
Synthesis of BuNENA in a continuous flow microreactor	3
Diphenylmethyl deprotection in continuous flow and its application in synthesis of β-lactam antibiotics	3
High-temperature S–S, S–O, and S–C bond transfer hydrogenolysis by lower alcohols in continuous flow mode	3
Formation of double emulsion droplets in flow-focusing microchips: a numerical parametric study	3
Investigation into a high-p,T,c continuous flow synthesis of myristyl-γ-picolinium chloride (MGPC) – a preservative in pharmaceutical formulations	3
Mediated formic acid flow fuel cell (MFAFFC) based on biomimetic electrolytes	3
Correction to: Continuous diameter increase reactor – a reactor concept for maximizing productivity by a controlled diameter extension	3
Multivariate curve resolution for kinetic modeling and scale-up prediction	2
Meet the Flow Chemist – Dr. Anna G. Slater	2
Slug flow as tool for selectivity control in the homogeneously catalysed solvent-free epoxidation of methyl oleate	2
Enzymatic kinetic resolution in flow for chiral mandelic acids	2
A multi-step continuous flow synthesis of pomalidomide	2
An eco-friendly and very low catalyst loading continuous condensation of primary amines and 1,3 Di carbonyl compounds: Synthesis of enaminones and enaminoesters by microreactor technology	2
Continuous flow synthesis of (E)-O-(3-chloro-2-propenyl)hydroxylamine: a key intermediate of clethodim	2
HO-SAS catalyzed protection and deprotection of aldehydes and alcohols in continuous flow reactors	2
Flow platform for the synthesis of benzodiazepines	2
Study of propane/air catalytic combustion in heat recirculating U-bend and spiral microcombustors	2
Micro-Batch flow reactor for the photoproduction of H2O2 from water/real seawater	2
Dominance of heat transfer limitations in conventional sol-gel synthesis of LTA revealed by microcrystallization	2
Imposed dynamic irradiation to intensify photocatalytic reactions	2
Nitration process of 2-(2,4-dichlorophenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one in a microreactor	2
Investigations on the continuous flow generation of 2,6-dichloro-N-fluoropyridinium tetrafluoroborate using F2 gas	2
Two photons are better than one: continuous flow synthesis of ꞵ-lactones through a doubly photochemically-activated Paternò-Büchi reaction	2
Investigating the effect of a monovalent ion on the droplet’s size and distribution in a surfactant-free droplet generation microfluidic chip	2
Gas-liquid mass transfer intensification for bubble generation and breakup in micronozzles	2
Efficient pinnick oxidation by a superheated micro-reaction process	2