OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Flow Chemistry is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Scalability of photochemical reactions in continuous flow mode	80
Oscillatory flow reactors for synthetic chemistry applications	67
Flow chemistry for process optimisation using design of experiments	32
Reactor design and selection for effective continuous manufacturing of pharmaceuticals	23
On-chip controlled synthesis of polycaprolactone nanoparticles using continuous-flow microfluidic devices	18
3-D printed microreactor for continuous flow oxidation of a flavonoid	18
Bulk Nanobubbles: generation using a two-chamber swirling flow nozzle and long-term stability in water	15
Continuous citrate‐capped gold nanoparticle synthesis in a two‐phase flow reactor	15
Flow chemistry experiments in the undergraduate teaching laboratory: synthesis of diazo dyes and disulfides	14
Continuous nitration of o-dichlorobenzene in micropacked-bed reactor: process design and modelling	14
Continuous hydrogenation of halogenated nitroaromatic compounds in a micropacked bed reactor	13
3D printed ceramics as solid supports for enzyme immobilization: an automated DoE approach for applications in continuous flow	13
An open source toolkit for 3D printed fluidics	12
Performance study and comparison between catalytic static mixer and packed bed in heterogeneous hydrogenation of vinyl acetate	11
High-pressure asymmetric hydrogenation in a customized flow reactor and its application in multi-step flow synthesis of chiral drugs	11
Novel feasibilities for preparation of serum albumin-based core-shell nanoparticles in flow conditions	11
Rational design of the inlet configuration of flow systems for enhanced mixing	9
A continuous flow bromodimethylsulfonium bromide generator: application to the synthesis of 2-arylaziridines from styrenes	9
Scaled up and telescoped synthesis of propofol under continuous-flow conditions	9
Development of large-scale oxidative Bromination with HBr-DMSO by using a continuous-flow microwave system for the subsequent synthesis of 4-Methoxy-2-methyldiphenylamine	9
Two step continuous-flow synthesis of benzocaine	9
Electrosynthesis of 3,3′,5,5’-Tetramethyl-2,2′-biphenol in Flow	9
Simultaneous self-optimisation of yield and purity through successive combination of inline FT-IR spectroscopy and online mass spectrometry in flow reactions	9
«Catalysis: a unified approach»: a new course in catalysis science and technology	8
Synthesis of new heterocyclic resveratrol analogues in milli- and microreactors: intensification of the Wittig reaction	8

Software-guided microscale flow calorimeter for efficient acquisition of thermokinetic data	8
Continuous synthesis of monodisperse silica microspheres over 1 μm size	8
Continuous-flow double diazotization for the synthesis of m-difluorobenzene via Balz-Schiemann reaction	8
Novel synthesis of PVA/GA hydrogel microspheres based on microfluidic technology	8
Process intensification in carbonylation of formaldehyde with active and passive enhancement methods	7
Flow field designs developed by comprehensive CFD model decrease system costs of vanadium redox-flow batteries	7
Continuous milli-scale reaction calorimeter for direct scale-up of flow chemistry	7
Discrimination of ablation, shielding, and interface layer effects on the steady-state formation of persistent bubbles under liquid flow conditions during laser synthesis of colloids	7
A microfluidic concentration gradient generator for simultaneous delivery of two reagents on a millimeter-sized sample	6
Analytical-scale synthesis of aryl-SF4Cl via flow microfluidic technology	6
Gas-liquid mass transfer intensification for bubble generation and breakup in micronozzles	6
Hydrogenation of nitroarenes in continuous flow with TPP/Raney Ni	6
Extending practical flow chemistry into the undergraduate curriculum via the use of a portable low-cost 3D printed continuous flow system	6
Slug flow as tool for selectivity control in the homogeneously catalysed solvent-free epoxidation of methyl oleate	6
Controllable preparation of double emulsion droplets in a dual-coaxial microfluidic device	6
Optimization of a 3D-printed tubular reactor for free radical polymerization by CFD	6
Continuous flow microfluidic implementation of a fluorescent marker into a polyacrylate moiety	6
Effect of residence time on the morphology of silica nanoparticles synthesized in a microfluidic reactor	5
Development of a packed-bed flow process for the production scale hydrogenation of 7-oxo-lithocholic acid to ursodeoxycholic acid	5
Mathematical model of gas-liquid or liquid-liquid Taylor flow with non-Newtonian continuous liquid in microchannels	5
Sucrose solution as a new viscous test fluid with tunable viscosities up to 2 Pas for micromixing characterization by the Villermaux–Dushman reaction	5
One-flow synthesis of tetrahydrocannabinol and cannabidiol using homo- and heterogeneous Lewis acids	5
Continuous synthesis of copper nanoparticles using a polyol process in a milli-channel reactor	5
Imposed dynamic irradiation to intensify photocatalytic reactions	5
Continuous flow synthesis of Celecoxib from 2-bromo-3,3,3-trifluoropropene	5
Complete chiral resolution in a continuous flow crystallizer with recycle stream	5
Delineating a green, catalyst free synthesis of a popular nutraceutical methylsulfonylmethane (MSM) in continuous flow	5
Innovative continuous synthesis of solketal	5
Fructose dehydration to hydroxyl-methylfurfural in an immobilized catalytic microreactor	4
Open-source multi-purpose sensor for measurements in continuous capillary flow	4
3D-printed device for synthesis of magnetic and metallic nanoparticles	4
Continuous flow organocatalyzed methoxycarbonylation of benzyl alcohol derivatives with dimethyl carbonate	4
Photoreduction synthesis of various azoxybenzenes by visible-light irradiation under continuous flow conditions	4
Process design of two-step mononitration of m-xylene in a microreactor	4
TfOH-catalyzed three-component synthesis of Dithiocarbamates from α-Diazoesters under continuous flow conditions	4
Practical and rapid construction of 2-pyridyl ketone library in continuous flow	4
Leveraging first-principles and empirical models for disturbance detection in continuous pharmaceutical syntheses	4
Bubbles size and mass transfer in a pulsating flow type apparatus with gas-liquid mixture	4
Continuous flow synthesis of xylidines via biphasic nitration of xylenes and nitro-reduction	4
Continuous-flow RAFT copolymerization of styrene and maleic anhydride: acceleration of reaction and effect of polymerization conditions on reaction kinetics	4
Synthesis of flow‐compatible Ru-Me/Al2O3 catalysts and their application in hydrogenation of 1-iodo-4-nitrobenzene	3
Nucleation in continuous flow cooling sonocrystallization for coiled capillary crystallizers	3
The impact of microfluidic reactor configuration on hydrodynamics, conversion and selectivity during indan oxidation	3
5-Hydroxymethylfurfural synthesis from fructose over deep eutectic solvents in batch reactors and continuous flow microreactors	3
Simultaneous production of hydrogen and acrylonitrile in a new bifunctional micro-reactor, mathematical modeling and optimization study	3
Rapid plugged flow synthesis of nucleoside analogues via Suzuki-Miyaura coupling and heck Alkenylation of 5-Iodo-2’-deoxyuridine (or cytidine)	3
Continuous synthesis of bromoalkyl glycosides by Fischer glycosylation in a microreactor	3
Continuous flow as a benign strategy for the synthesis of Thioesters via selective C-N bond cleavage	3
Continuous flow synthesis of HMF from glucose using gadolinium (III) trifluoromethanesulfonate in Brønsted acidic ionic liquid as a catalytic system	3
3D printed reactors and Kessil lamp holders for flow photochemistry: design and system standardization	3

Micro-Batch flow reactor for the photoproduction of H2O2 from water/real seawater	3
Simultaneous determination of enthalpy of mixing and reaction using milli-scale continuous flow calorimetry	3
Flow dearomatization of electron-poor 3-fluoromethylthioindoles by 1,3-dipolar cycloaddition	3
Inline monitoring of high ammonia concentrations in methanol with a customized 3D printed flow cell	3
Continuous-flow synthesis of N,N′-bis(2,2,6,6-tetramethyl-4-piperidinyl)-1,6-hexanediamine (DTMPA) in a Micro fixed-bed reactor	3
FOMSy: 3D-printed flexible open-source microfluidic system and flow synthesis of PET-tracer	3
Development of an automated flow chemistry affinity-based purification process for DNA-encoded chemistry	2
Advances in continuous polymer analysis in flow with application towards biopolymers	2
Design and scale-up of continuous di-nitration reaction using pinched tube flow reactor	2
Telescoped continuous flow synthesis of phenyl acrylamide	2
Continuous heterogeneous synthesis of hexafluoroacetone and its machine learning-assisted optimization	2
The applications of organozinc reagents in continuous flow chemistry: Negishi coupling	2
A multi-step continuous flow synthesis of pomalidomide	2
Investigating the effect of nonionic surfactant on the silica nanoparticles formation and morphology in a microfluidic reactor	2
Magnet-actuated microfluidic reactors with controllable Fe-based amorphous microspheres for tetracycline degradation	2
Voltage-driven microfluidic synthesis of magnetite and gold nanomaterials	2
Kinetic analysis of the partial synthesis of artemisinin: Photooxygenation to the intermediate hydroperoxide	2
Future medicinal chemists experience flow chemistry: optimization by experimental design of the limiting synthetic step to the antifungal drug econazole nitrate	2
Kinetics and safeties of 2-Ethyl-1-hexanol nitration in a capillary-microreactor	2
Editorial special issue in the journal of flow chemistry: engineering aspects of flow chemistry	2
Continuous Flow Generation of Highly Reactive Organometallic Intermediates: A Recent Update	2
Continuous flow Friedel–Crafts acetylation of phenols and electron-rich arenes and heteroarenes	2
Continuous flow synthesis of phenyl glucosazone and its conversion to 2H-1,2,3-Triazole building blocks	2
A facile iron catalyzed cross-coupling reaction under micro-flow conditions	2
Enzymatic kinetic resolution in flow for chiral mandelic acids	2
Ion mobility spectrometry-tandem mass spectrometry strategies for the on-line monitoring of a continuous microflow reaction	2
A revised 1D equivalent model for the determination of incident photon flux density in a continuous-flow LED-driven spiral-shaped microreactor using the actinometry method with Reinecke’s salt	2
Development of a continuous flow process for the synthesis of mesotrione	2
Lithium aluminum hydride in flow: overcoming exotherms, solids, and gas evolution en route to chemoselective reductions	2
Chemoselective borylation of bromoiodoarene in continuous flow: synthesis of bromoarylboronic acids	2
Continuous diameter increase reactor – a reactor concept for maximizing productivity by a controlled diameter extension	1
Investigating the effect of a monovalent ion on the droplet’s size and distribution in a surfactant-free droplet generation microfluidic chip	1
Flow platform for the synthesis of benzodiazepines	1
The synthesis of Aspirin and Acetobromo-α-D-glucose using 3D printed flow reactors: an undergraduate demonstration	1
Continuous-flow synthesis of 7-methoxy-1-tetralone: an important intermediate of (-)-Dezocine	1
Safe and on-demand protocol for the continuous generation of SO2 and Cl2 for subsequent utilization in organic synthesis	1
Telescoped synthesis of vicinal diamines via ring-opening of electrochemically generated aziridines in flow	1
Perspectives on flow biocatalysis: the engine propelling enzymatic reactions	1
Scale-out production in core-annular liquid–liquid microextractor	1
Multistep batch-flow hybrid synthesis of a terbinafine precursor	1
A tri-fluid tortuous microfluidic chip for green synthesis of nanoparticles and inactivation of a model gram-negative bacteria: Intracellular components evaluation	1
Sizing of a washcoated reactor for the catalytic oxidation of propylene to acrolein on a solid bismuth/molybdate catalyst	1
Accurate determination of the kinetics of toluene nitration in a liquid–liquid microflow system	1
Implementing flow chemistry in education: the NSERC CREATE program in continuous flow science	1
Continuous flow synthesis of the lamivudine precursor L-Menthyl Glyoxylate	1
Continuous microflow synthesis of dimethyl-substituted cyclobutanetetracarboxylic dianhydrides and its application on polyimide films	1
Optimization of continuous-flow diphenyldiazomethane synthesis: an integrated undergraduate chemistry experiment	1
Effects of two-phase periodic velocity on droplet coalescence inside microchannels	1
Metal-free catalyzed aerobic oxidation of 2-nitro-4-methylsulfone toluene to 2-nitro-4-methylsulfonylbenzoic acid using a continuous-flow reactor	1
Efficient scale up of photochemical bromination of conjugated allylic compounds in continuous-flow	1
Catalyst-free biphasic oxidation of Thiophenes in continuous-flow	1
Achieving selectivity in porphyrin bromination through a DoE-driven optimization under continuous flow conditions	1
Aerobic oxidation of hydroxymethylfurfural using a homogeneous TEMPO/TBN catalytic system in 3D-printed milli-scale porous reactors	1
Improving the reaction efficiency of condensation amidation of piperazine with benzoic acid based on kinetics study in microreactors	1
Proposal of the reaction environment for effective use of structured catalyst	1
Continuous flow reduction of 4-nitrophenol by “water soluble” palladium nanoparticles: from batch to continuous flow system	1
Continuous-flow microfluidic device for synthesis of cationic porous polystyrene microspheres as sorbents of p-xylene from physiological saline	1
One-step microdevices for synthesizing morphology-controlled ultraviolet-curable polysiloxane shell particles	1
Correction to: The applications of organozinc reagents in continuous flow chemistry: Negishi coupling	1
3D investigations of microscale mixing in helically coiled capillaries	1
Direct electrochemical reduction of ethyl isonicotinate to 4-pyridinemethanol in an undivided flow reactor	1
CFD analysis of asymmetric mixing at different inlet configurations of a split-and-recombine micro mixer	1
Synthesis of 2,3,5-trimethylbenzoquinone from 2,3,6-trimethylphenol and tert-butyl hydroperoxide in microreactors	1
Scalable synthesis of selective hydrodeoxygenation inverted Pd@TiO2 nanocatalysts	1
Synthesis of arenediazonium salts and Suzuki- Miyaura cross-coupling reaction in microreactors	1
Continuous synthesis of benzaldehyde by ozonolysis of styrene in a micro-packed bed reactor	1
A practical experiment to teach students continuous flow and physico-chemical methods: acetylation of ethylene diamine in liquid bi-phase	1
A small footprint oxycodone generator based on continuous flow technology and real-time analytics	1
The continuous flow synthesis of azos	1
A perspective on automated advanced continuous flow manufacturing units for the upgrading of biobased chemicals toward pharmaceuticals	1
Challenges in transfer of gas-liquid reactions from batch to continuous operation: dimensional analysis and simulations for aerobic oxidation	1
Selective monosubstitution on a trichlorosilane with highly reactive organolithium compounds in a microflow reactor	1