Signal Transduction and Targeted Therapy

Article	Citations
Loss of FBXL14 promotes mesenchymal shift and radioresistance of non-small cell lung cancer by TWIST1 stabilization	1458
Massively parallel interrogation of human functional variants modulating cancer immunosurveillance	1431
Greasy hair against obesity	1374
Correction: Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine	1198
Correction: The Hippo signalling pathway and its implications in human health and diseases	1025
Gut microbes regulate the feeding center: a new discovery of Gut Brain Axis	1002
Cocktails of defined chemical compounds: sufficient to induce totipotency in embryonic stem cells	959
Peptide targeting the interaction of S protein cysteine-rich domain with Ezrin restricts pan-coronavirus infection	844
CD4 T cell contact drives macrophage cell cycle G0-G1 transition	834
Somatic mutant clone screening: scan for novel NASH target genes in mouse liver	743
Robust neutralizing antibody response to the XBB.1.5 trivalent recombinant protein vaccine booster	697
Sensory neurons: unveiling the symphony of wound healing	665
Deciphering the molecular basis of lipoprotein recognition and transport by LolCDE	644
Moving towards precision psychiatry: the hard nut of depression	597
Correction: Ribosomal modification protein rimK-like family member A activates betaine-homocysteine S-methyltransferase 1 to ameliorate hepatic steatosis	580
Renal remodeling by CXCL10-CXCR3 axis-recruited mesenchymal stem cells and subsequent IL4I1 secretion in lupus nephritis	577
Dietary restriction interventions: lifespan benefits need resilience and are limited by immune compromise and genetics	572
A broadly neutralizing antibody against the SARS-CoV-2 Omicron sub-variants BA.1, BA.2, BA.2.12.1, BA.4, and BA.5	565
Identification of glutamine as a potential therapeutic target in dry eye disease	565
PD-1 and LAG-3: synergistic fostering of T cell exhaustion	559
PIM1 kinase facilitates Zika virus replication by suppressing host cells’ natural immunity	557
Comparing acute versus AIDS ART initiation on HIV-1 integration sites and clonal expansion	540
A donor PD-1+CD8+ TSCM-like regulatory subset mobilized by G-CSF alleviates recipient acute graft-versus-host-disease	530
Phototherapy in cancer treatment: strategies and challenges	527
Tamoxifen and clomiphene inhibit SARS-CoV-2 infection by suppressing viral entry	516

S19W, T27W, and N330Y mutations in ACE2 enhance SARS-CoV-2 S-RBD binding toward both wild-type and antibody-resistant viruses and its molecular basis	486
Recombinant XBB.1.5 boosters induce robust neutralization against KP.2- and KP.3-included JN.1 sublineages	476
Outcome of aggressive B-cell lymphoma with TP53 alterations administered with CAR T-cell cocktail alone or in combination with ASCT	473
Palmitoylation of SARS-CoV-2 S protein is essential for viral infectivity	462
Sera proteomic features of active and recovered COVID-19 patients: potential diagnostic and prognostic biomarkers	462
Metabolic reprogramming of proinflammatory macrophages by target delivered roburic acid effectively ameliorates rheumatoid arthritis symptoms	461
Photodynamic gel-bombs enhance tumor penetration and downstream synergistic therapies	444
SARS-CoV-2 envelope protein impairs airway epithelial barrier function and exacerbates airway inflammation via increased intracellular Cl− concentration	436
Efficacy and safety of PD-1 blockade plus long-course chemoradiotherapy in locally advanced rectal cancer (NECTAR): a multi-center phase 2 study	433
Next-generation mpox vaccines: efficacy of mRNA-1769 compared to modified vaccinia virus Ankara in non-human primates	425
Sintilimab (anti-PD-1 antibody) plus chidamide (histone deacetylase inhibitor) in relapsed or refractory extranodal natural killer T-cell lymphoma (SCENT): a phase Ib/II study	419
Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cells	417
Neoadjuvant nivolumab with or without platinum-doublet chemotherapy based on PD-L1 expression in resectable NSCLC (CTONG1804): a multicenter open-label phase II study	416
A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancer	416
G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders	414
Immunotherapy in hematologic malignancies: achievements, challenges and future prospects	405
Signal pathways of melanoma and targeted therapy	400
Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases	391
Membraneless organelles in health and disease: exploring the molecular basis, physiological roles and pathological implications	385
Animal models for COVID-19: advances, gaps and perspectives	378
SARS-CoV-2 Omicron strain exhibits potent capabilities for immune evasion and viral entrance	373
Neutrophil extracellular traps in homeostasis and disease	372
Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness	362
Broadly neutralizing antibodies against Omicron-included SARS-CoV-2 variants induced by vaccination	359
Boosting liver regeneration: kinase inhibitor as a new tool to prevent liver failure	359
Impact of mechanical circulatory support and immunomodulation therapy on outcome of patients with fulminant myocarditis: Chinese registry of fulminant myocarditis	355
From tuberculosis bedside to bench: UBE2B splicing as a potential biomarker and its regulatory mechanism	350
Bone-targeting engineered small extracellular vesicles carrying anti-miR-6359-CGGGAGC prevent valproic acid-induced bone loss	349
Generation of in situ CRISPR-mediated primary and metastatic cancer from monkey liver	342
Single-cell transcriptomic profiling unravels the adenoma-initiation role of protein tyrosine kinases during colorectal tumorigenesis	331
Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progression	328
Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy	317
Age-induced changes in lung microenvironment: from melanoma dormancy to outgrowth	316
TSPAN32 suppresses chronic myeloid leukemia pathogenesis and progression by stabilizing PTEN	313
Exploiting a chink in the armor: engineering broadly neutralizing monoclonal antibodies for SARS-like viruses	303
Nanobody-based bispecific T-cell engager (Nb-BiTE): a new platform for enhanced T-cell immunotherapy	299
Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy	299
Top(ological-operon) secret behind the long-range transcriptional coupling	298
Omicron spike protein: a clue for viral entry and immune evasion	292
PIKfyve inhibitors against SARS-CoV-2 and its variants including Omicron	290
Beyond borders: the choroid plexus-immune communication during neuroinflammation	289
Spatial TIME landscape and its prognostic value in the lung and brain tumor: location matters	286
SARS-CoV-2 infection of monocytes: balancing acts of antibodies and inflammasomes	274
Non-small cell lung cancers (NSCLCs) oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitors	271
Exploration and functionalization of M1-macrophage extracellular vesicles for effective accumulation in glioblastoma and strong synergistic therapeutic effects	266
Klotho in Osx+-mesenchymal progenitors exerts pro-osteogenic and anti-inflammatory effects during mandibular alveolar bone formation and repair	257
Harnessing innate immune pathways for therapeutic advancement in cancer	256
The RING finger protein family in health and disease	248
Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases	245
Potassium voltage-gated channel subfamily H member 2 (KCNH2) is a promising target for incretin secretagogue therapies	245

Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions	244
Escaping alveolar macrophage endosomal retention explains massive expansion of SARS-CoV-2 delta variant	241
Microbiota in health and diseases	241
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma	236
Base editing: a promising tool to rescue spinal muscular atrophy	235
Targeting menin: a promising therapeutic strategy for susceptible acute leukemia subtypes	233
Correction: Durable and enhanced immunity against SARS-CoV-2 elicited by manganese nanoadjuvant formulated subunit vaccine	231
SARS-CoV-2 Omicron subvariant BA.2.86: limited potential for global spread	230
Predicting the next move: tracking the complexity of lung cancer evolution and metastasis	228
Landscape of antitumor CD4+ T cells in melanoma:unraveling novel HLA class II-driven immune escape	226
Modulating the tumor microenvironment via oncolytic virus and PI3K inhibition synergistically restores immune checkpoint therapy response in PTEN-deficient glioblastoma	223
Enhancer transcription profiling reveals an enhancer RNA-driven ferroptosis and new therapeutic opportunities in prostate cancer	222
Mind-body control: a new perspective on motor neuron function	222
Low levels of neutralizing antibodies against XBB Omicron subvariants after BA.5 infection	220
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry	220
Waning humoral immune responses to inactivated SARS-CoV-2 vaccines in patients with severe liver disease	219
RUNX1 promotes mitophagy and alleviates pulmonary inflammation during acute lung injury	215
Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity	215
HLA-mismatched allogeneic adoptive immune therapy in severely immunosuppressed AIDS patients	215
Mitochondrial heterogeneity in diseases	213
Persistent SARS-CoV-2 infection in asymptomatic young adults	211
STING aggravates ferroptosis-dependent myocardial ischemia-reperfusion injury by targeting GPX4 for autophagic degradation	208
Targeting HECTD3-IKKα axis inhibits inflammation-related metastasis	207
Small molecules in the treatment of COVID-19	206
A20 attenuates oxidized self-DNA-mediated inflammation in acute kidney injury	205
CNTNAP2 intracellular domain (CICD) generated by γ-secretase cleavage improves autism-related behaviors	203
Discovery of IHMT-MST1-39 as a novel MST1 kinase inhibitor and AMPK activator for the treatment of diabetes mellitus	203
Linking B cell metabolism to immune regulation: the neurotransmitter GABA	199
sRAGE alleviates SARS-CoV-2-induced pneumonia in hamster	198
Metaplastic epithelial cells: origination from stem cells and promotion of intestinal inflammation	198
IRE1α: a gatekeeper of chemotherapy-induced immunogenicity in triple-negative breast cancer	197
Nascent mRNA damage: depot and disposal	197
Semaphorin 3C (Sema3C) reshapes stromal microenvironment to promote hepatocellular carcinoma progression	196
DNA framework signal amplification platform-based high-throughput systemic immune monitoring	193
Identification of NOXA as a pivotal regulator of resistance to CAR T-cell therapy in B-cell malignancies	189
Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy	189
Intranasal booster using an Omicron vaccine confers broad mucosal and systemic immunity against SARS-CoV-2 variants	188
GRP75 triggers white adipose tissue browning to promote cancer-associated cachexia	188
Homeostasis and metabolism of iron and other metal ions in neurodegenerative diseases	188
Remolding the tumor microenvironment by bacteria augments adoptive T cell therapy in advanced-stage solid tumors	187
Lactate metabolism in human health and disease	185
Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study	184
Molecular insights of exercise therapy in disease prevention and treatment	183
Engineering strategies to enhance oncolytic viruses in cancer immunotherapy	183
Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy	179
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities	177
Endoplasmic reticulum stress: molecular mechanism and therapeutic targets	175
Targeting PI3K/Akt signal transduction for cancer therapy	172
Comprehensive snapshots of natural killer cells functions, signaling, molecular mechanisms and clinical utilization	170
Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome	170
Post-fast refeeding: rise of intestinal stemness and mutagen-induced cancer risk through polyamine metabolism	165
RNA interfering machinery: new insight into the Dicer-2 complexes in the dsRNA-processing cycle	165
A new treatment for sarcoma extracted from combination of miRNA deregulation and gene association rules	164
SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer	163
Inactivated SARS-CoV-2 induces acute respiratory distress syndrome in human ACE2-transgenic mice	161
Mutually exclusive epigenetic modification on SIX6 with hypermethylation for precancerous stage and metastasis emergence tracing	161
New regulators of systemic iron homeostasis	160
Correction: A systemic and molecular study of subcellular localization of SARS-CoV-2 proteins	159
Phosphorylation determines the glucose metabolism reprogramming and tumor-promoting activity of sine oculis homeobox 1	159
Combination therapy for HCC: from CRISPR screening to the design of clinical therapies	157
Targeting complement hyperactivation: a novel therapeutic approach for severe pneumonia induced by influenza virus/staphylococcus aureus coinfection	157
Single-cell genomics: the human biomolecular and cell atlases	157
Mefatinib as first-line treatment of patients with advanced EGFR-mutant non-small-cell lung cancer: a phase Ib/II efficacy and biomarker study	156
Early intermittent cholesterol exposure accelerates atherosclerosis: an oscillating amplifier calling for preemptive control	155
A phase II clinical trial of toripalimab in advanced solid tumors with polymerase epsilon/polymerase delta (POLE/POLD1) mutation	155
C/EBPβ activation in vascular smooth muscle cells promotes hyperlipidemia-induced phenotypic transition and arterial stiffness	154
Targeting TM4SF1 exhibits therapeutic potential via inhibition of cancer stem cells	152
Multi-omics analysis reveals RNA splicing alterations and their biological and clinical implications in lung adenocarcinoma	152
SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication	152
Targeting chaperon protein HSP70 as a novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia	152
Rapid isolation and immune profiling of SARS-CoV-2 specific memory B cell in convalescent COVID-19 patients via LIBRA-seq	152
A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants	149
Programmable synthetic receptors: the next-generation of cell and gene therapies	149
B-cell immune checkpoint TIM-1: a potential target for tumour immunotherapy	149
Epigenetic regulation of TP53 is involved in prostate cancer radioresistance and DNA damage response signaling	144
Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer	144
HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19	144
Back to pluripotency: fully chemically induced reboot of human somatic cells	143
SRY-Box transcription factor 9 triggers YAP nuclear entry via direct interaction in tumors	143
RNA binding protein TIAR modulates HBV replication by tipping the balance of pgRNA translation	142

Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration	141
2D4, a humanized monoclonal antibody targeting CD132, is a promising treatment for systemic lupus erythematosus	139
Gold nanoparticles combat enveloped RNA virus by affecting organelle dynamics	135
Signaling pathways and targeted therapies for psoriasis	135
Fusobacterium nucleatum enhances the efficacy of PD-L1 blockade in colorectal cancer	134
ELANE: an emerging lane to selective anticancer therapy	133
mRNA-based therapeutics: powerful and versatile tools to combat diseases	132
Inflammation and tumor progression: signaling pathways and targeted intervention	130
Angiogenic signaling pathways and anti-angiogenic therapy for cancer	130
Deconstructing the intra-tumor subclonal heterogeneity of lung synchronous ground-glass nodules using whole-genome sequencing	127
Role of the miR-301a/Fra-2/GLIPR1 axis in lung cancer cisplatin resistance	126
Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone	125
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein	120
Phenotypic characteristics and T cell receptor properties in melanoma: deciphering the correlation at single-cell resolution	119
Checkpoint blockade therapy in Hodgkin lymphoma: improved response through combination with JAK inhibition	118
Intervening pyruvate carboxylase stunts tumor growth by strengthening anti-tumor actions of tumor-associated macrophages	118
An anti-tumor coup: TIM3 ablation activates the immune arsenal	117
Toripalimab plus chemotherapy for first line treatment of advanced non-small cell lung cancer (CHOICE-01): final OS and biomarker exploration of a randomized, double-blind, phase 3 trial	117
Time’s up: mutation rate and lifespan	116
Surufatinib plus toripalimab combined with etoposide and cisplatin as first-line treatment in advanced small-cell lung cancer patients: a phase Ib/II trial	115
Oocyte TET3: an epigenetic modifier responsible for maternal inheritance of glucose intolerance	114
Balancing memory in sleep: firing barrages as a circuit breaker for reactivation	114
Modularization of adhesion G protein-coupled receptor (aGPCR) structure: how alternative splicing regulates synaptogenesis	113
Intranasal adenovirus-vectored Omicron vaccine induced nasal immunoglobulin A has superior neutralizing potency than serum antibodies	112
Adhesion G protein-coupled receptor latrophilin 1 (ADGRL1): a novel regulator of glucose and energy homeostasis	112
Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs	112
Activated STING: an ion channel to trigger non-interferon-related functions	112
Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines	111
Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease	110
Sintilimab (anti-PD-1 antibody) combined with high-dose methotrexate, temozolomide, and rituximab (anti-CD20 antibody) in primary central nervous system lymphoma: a phase 2 study	110
I prostanoid receptor activation attenuates pressure overload-induced cardiac hypertrophy by enhancing glucose oxidation	110
Immunogenicity and protective efficacy of a recombinant protein subunit vaccine and an inactivated vaccine against SARS-CoV-2 variants in non-human primates	108
Targeting tumor microenvironment with antibody-guided IL-2 pro-cytokine promotes and rejuvenates dysfunctional CD8+ T cells	108
LIX1-like protein drives hepatic stellate cell activation to promote liver fibrosis by regulation of chemokine mRNA stability	106
A PD-L1-targeting chimeric switch receptor enhances efficacy of CAR-T cell for pleural and peritoneal metastasis	104
Toripalimab combined with lenvatinib and GEMOX is a promising regimen as first-line treatment for advanced intrahepatic cholangiocarcinoma: a single-center, single-arm, phase 2 study	102
Neoleukin-2/15-armored CAR-NK cells sustain superior therapeutic efficacy in solid tumors via c-Myc/NRF1 activation	101
Environment impacts sexual preference: dopamine sends signals under pressure to decide which sex you like	100
Aptamers targeting SARS-CoV-2 nucleocapsid protein exhibit potential anti pan-coronavirus activity	99
Synthetic lethality by PARP inhibitors: new mechanism uncovered based on unresolved transcription-replication conflicts	97
Sequential infection with H1N1 and SARS-CoV-2 aggravated COVID-19 pathogenesis in a mammalian model, and co-vaccination as an effective method of prevention of COVID-19 and influenza	97
Hypoxia-inducible factor upregulation by roxadustat attenuates drug reward by altering brain iron homoeostasis	97
Asialoglycoprotein receptor 1 promotes SARS-CoV-2 infection of human normal hepatocytes	97
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism	96
Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential	96
The biological applications of DNA nanomaterials: current challenges and future directions	95
Oit3, a promising hallmark gene for targeting liver sinusoidal endothelial cells	95
Targeted protein degradation: advances in drug discovery and clinical practice	94
T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape	94
Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy	93
Targeting signaling pathways in prostate cancer: mechanisms and clinical trials	93
Redox regulation: mechanisms, biology and therapeutic targets in diseases	92
ALYREF mediates RNA m5C modification to promote hepatocellular carcinoma progression	91
Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future	91
Signaling pathways in obesity: mechanisms and therapeutic interventions	91
Artificial intelligence in cancer target identification and drug discovery	90
CHIKV mRNA vaccines encoding conserved structural/envelope proteins confer broad cross-lineage protection against infection	89
A systemic look at pancreatic cancer patients: Predicting metastasis by studying the liver	89
Targeting circular RNAs as a therapeutic approach: current strategies and challenges	89
SLC7A11: a new regulator in diabetic wound healing	88
Route, origin & valence matter: towards sophisticated next-generation vaccines to cope with the COVID-19 pandemic	88
Gut dysbiosis conveys psychological stress to activate LRP5/β-catenin pathway promoting cancer stemness	88
Curse and blessing: upregulation of oncogenes upon treatment with hypomethylating agents in myelodysplastic syndrome	87
Safety and efficacy of trifluridine/tipiracil +/− bevacizumab plus XB2001 (anti-IL-1α antibody): a single-center phase 1 trial	87
Patient-reported outcomes of rezvilutamide versus bicalutamide in combination with androgen deprivation therapy in high-volume metastatic hormone-sensitive prostate cancer patients (CHART): a randomiz	87
Clinical and biomarker analyses of SHR-1701 combined with famitinib in patients with previously treated advanced biliary tract cancer or pancreatic ductal adenocarcinoma: a phase II trial	87
Redox signaling-governed drug-tolerant persister cancer cell: a key spark of treatment failure	87
Artificial intelligence propels lung cancer screening: innovations and the challenges of explainability and reproducibility	86
Human cross-tissue cell atlases: unprecedented resources towards systematic understanding of physiology and diseases	86
Hypocretin neuron hyperexcitability in the hypothalamus: a newly discovered culprit in aging-related sleep impairment	86
Human genetic basis of coronavirus disease 2019	84
The DNMT1-PAS1-PH20 axis drives breast cancer growth and metastasis	83
Perioperative sintilimab and neoadjuvant anlotinib plus chemotherapy for resectable non-small-cell lung cancer: a multicentre, open-label, single-arm, phase 2 trial (TD-NeoFOUR trial)	83
Mutation-independent gene knock-in therapy targeting 5′UTR for autosomal dominant retinitis pigmentosa	83
IL-17 signaling in skin repair: safeguarding metabolic adaptation of wound epithelial cells	83
Uveal melanoma with a GNA11/GNAQ mutation secretes VEGF for systemic spread	83
Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes	82
NK cell dysfunction in severe COVID-19: TGF-β-induced downregulation of integrin beta-2 restricts NK cell cytotoxicity	82
miR-133b targets NCAPH to promote β-catenin degradation and reduce cancer stem cell maintenance in non-small cell lung cancer	82
Combination therapy with saxagliptin and vitamin D for the preservation of β-cell function in adult-onset type 1 diabetes: a multi-center, randomized, controlled trial	82
SCGN deficiency is a risk factor for autism spectrum disorder	81
SARS-CoV-2-specific immune response in COVID-19 convalescent individuals	81
Genetic differences between primary and metastatic cancer: a pan-cancer whole-genome comparison study	81
Elemene sensitizes pancreatic cancer cells to bortezomib by enhancing proteasome inhibition via molecular patch mechanism	80
FGF7 enhances the expression of ACE2 in human islet organoids aggravating SARS-CoV-2 infection	80
Progression from ductal carcinoma in situ to invasive breast cancer: molecular features and clinical significance	79
Neoadjuvant oncolytic virus orienx010 and toripalimab in resectable acral melanoma: a phase Ib trial	79
Cross-neutralization and cross-protection among SARS-CoV-2 viruses bearing different variant spikes	78
The tumor-enriched small molecule gambogic amide suppresses glioma by targeting WDR1-dependent cytoskeleton remodeling	78
Three doses of prototypic SARS-CoV-2 inactivated vaccine induce cross-protection against its variants of concern	78
PARP1-DNA co-condensation: the driver of broken DNA repair	77
tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis	77
Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure	76
A pan-cancer fingerprint: common molecular denominators of the human tumor microenvironment	76
Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1	76