Cell Death Discovery

Article	Citations
Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis	489
Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model	289
MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway	246
POLE2 promotes osteosarcoma progression by enhancing the stability of CD44	230
AXL tyrosine kinase inhibitor TP-0903 induces ROS trigger neuroblastoma cell apoptosis via targeting the miR-335-3p/DKK1 expression	227
PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway	201
Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion	174
N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction	164
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death	147
An mTOR and DNA-PK dual inhibitor CC-115 hinders non-small cell lung cancer cell growth	147
STING agonists trigger monocyte death via apoptosis, pyroptosis, caspase-8 activation and mitochondrial dysfunction	146
ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues	141
Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma	139
Hippo pathway and NLRP3-driven NETosis in macrophages: Mechanisms of viral pneumoniaaggravation	137
N6-methyladenosine: a key regulator in ocular disease mechanisms and treatment	135
New insights into constitutive neutrophil death	132
CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma	127
RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation	125
Matrix metalloproteinase-10 promotes kidney fibrosis by transactivating β-catenin signaling	118
USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression	117
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics	117
Exploring necroptosis: mechanistic analysis and antitumor potential of nanomaterials	116
Retraction Note to: Inhibition of TGF-β repairs spinal cord injury by attenuating EphrinB2 expressing through inducing miR-484 from fibroblast	114
MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1	112
GILT stabilizes cofilin to promote the metastasis of prostate cancer	107

Absence of Rnf126 causes male infertility with multiple morphological abnormalities of the sperm flagella	106
Epitranscriptomic control of cancer: the emerging roles of m⁵C and ac⁴C RNA modifications	104
Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis	104
Long non-coding RNA-encoded micropeptides: functions, mechanisms and implications	104
USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target	103
Metformin protects retinal ganglion cells in a preclinical model of retinal ischemia/reperfusion injury and stabilizes visual field in diabetic patients with glaucoma	102
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1	99
LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism	98
Lipids associated with autophagy: mechanisms and therapeutic targets	97
Dual control of liver regeneration by Nr1d1 homeostasis and Klf2 checkpoint	95
Diverse functions of NLRP3 inflammasome in PANoptosis and diseases	95
LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma	95
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH	94
Oncometabolite signatures from tumor-stroma crosstalk as potential non-invasive biomarkers	94
Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis	93
The plasticity of epithelial cells and its potential in the induced differentiation of gastric cancer	88
FKBP5 isoforms shape immune pathways related to tumor tolerance	87
Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis	87
Therapeutic targeting of STING-IL6/STAT3 axis to inhibit osteoclastic niche formation and breast cancer bone metastasis	87
Exosomal circRNAs: key modulators in breast cancer progression	86
Targeting the ODC1-YBX1 axis reverses gastric cancer chemoresistance via transcriptional control of SLC7A11-mediated ferroptosis	81
The role of ankyrin repeat-containing proteins in epigenetic and transcriptional regulation	80
Dysregulated nuclear Lamin B1 in DYT1 dystonia thickens nuclear lamina and disrupts 14-3-3 proteins	80
AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury	79
Stem cell-derived intestinal organoids: a novel modality for IBD	79
Targeting mitochondrial autophagy for anti-aging	78
Radiobiological characterisation of a 28 MeV proton beam delivered by the MC-40 cyclotron	78
Vascular smooth muscle cell metabolic reprogramming and phenotypic remodeling in atherosclerosis	77
Tissue microenvironment induces tissue specificity of ILC2	76
Cellular senescence of renal tubular epithelial cells in acute kidney injury	76
Smoking-induced microbial dysbiosis: a key driver of systemic diseases and emerging therapeutic opportunities	76
The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer	76
Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc42	75
IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL10	75
Mitochondrial metabolic reprogramming in colorectal cancer: mechanisms of resistance and future clinical interventions	74
Inhibition of TGF-beta signaling protects from alpha-synuclein induced toxicity	73
Fosinopril mediates antitumor efficacy by inducing GSDME-dependent pyroptosis in NSCLC	72
BRD7 suppresses tumor chemosensitivity to CHK1 inhibitors by inhibiting USP1-mediated deubiquitination of CHK1	71
MiR-134-5p inhibits the malignant phenotypes of osteosarcoma via ITGB1/MMP2/PI3K/Akt pathway	71
Epirubicin induces cardiotoxicity through disrupting ATP6V0A2-dependent lysosomal acidification and triggering ferroptosis in cardiomyocytes	71
LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins	70
MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling	70
Differential effects of HDAC inhibitors in the RhoI255d mouse model for autosomal dominant retinitis pigmentosa	69
The EZH2-H3K27me3 axis modulates aberrant transcription and apoptosis in cyclophosphamide-induced ovarian granulosa cell injury	69
Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress	64
Dynamic changes of the immune microenvironment in ovarian cancer following neoadjuvant chemotherapy	64
In vitro cytotoxic mechanisms of Pt(O,O′-acac)(γ-acac)(DMS): mitochondrial dysfunction and impaired autophagy in U251 cell line	64
Neddylation inhibition induces DNA double-strand breaks, hampering tumor growth in vivo, and promotes radiosensitivity in PAX3–FOXO1 rhabdomyosarcoma	63
CREB suppresses PGRP-SC2 to drive age-related immune senescence and gut dysbiosis in Drosophila	63
NRF2 transcriptionally regulates Caspase-11 expression to activate HMGB1 release by Autophagy-deficient hepatocytes	62

Modulation of stress granules by lobeline increases cell death in hypoxia and impacts the ability of glioblastoma cells to secrete extracellular vesicles	62
Correction: Let-7b-5p inhibits breast cancer cell growth and metastasis via repression of hexokinase 2-mediated aerobic glycolysis	62
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4	61
From mechanisms to markers: role of pyroptosis in revolutionizing thyroid cancer care	61
APOE4 promotes nigral tau hyperphosphorylation through cholesterol in atherosclerosis	61
Fexofenadine protects against osteoarthritis by targeting Smad2 and STAT1 to enhance anabolism and binding cPLA2 to inhibit catabolism	61
NAT10 promotes cisplatin resistance and immune escape by increasing the expression of DUSP1 and PD-L1 in gastric cancer	60
VDR and deubiquitination control neuronal oxidative stress and microglial inflammation in Parkinson’s disease	60
YAP is required for prostate development, regeneration, and prostate stem cell function	60
IL-8 activates fibroblasts to promote the invasion of HNSCC cells via STAT3-MMP1	60
Circadian rhythm regulates the function of immune cells and participates in the development of tumors	60
Gemcitabine elaidate and ONC201 combination therapy for inhibiting pancreatic cancer in a KRAS mutated syngeneic mouse model	60
Exploring the metabolic signaling network of GFPT in cancer	60
Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway	58
Thapsigargin triggers a non-apoptotic, caspase-independent programmed cell death in basophilic leukaemia cells	58
Inhibition of RIPK1/RIPK3-MLKL inflammatory signaling pathway activation attenuates preterm birth	58
Hexamethylene amiloride induces lysosome-mediated cell death in multiple myeloma through transcription factor E3	58
Immunotherapy for autoimmune encephalitis	58
TRPS1 regulates the opposite effect of progesterone via RANKL in endometrial carcinoma and breast carcinoma	56
CD95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a CD95 ligand-independent manner	56
LncRNA in tumorigenesis of non-small-cell lung cancer: From bench to bedside	55
Heat shock protein 90α reduces CD8+ T cell exhaustion in acute lung injury induced by lipopolysaccharide	55
Methylation in cornea and corneal diseases: a systematic review	55
Targeting Txnip-mediated metabolic reprogramming has therapeutic potential for osteoarthritis	55
Correction: Autophagy in hepatic ischemia–reperfusion injury	55
COVID-19 related neurological manifestations in Parkinson’s disease: has ferroptosis been a suspect?	54
Metabolic reprogramming in melanoma therapy	54
Disruption of thrombospondin 1/2-integrin β1 axis impairs cell adhesion and tumor growth in intrahepatic cholangiocarcinoma	54
Repurposing proteasome inhibitors for improved treatment of triple-negative breast cancer	54
Comprehensive analysis of cellular metrics: From proliferation to mitochondrial membrane potential and cell death in a single sample	54
Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer	53
Exosomal miR-122-5p from tubular cells ameliorates renal interstitial fibrosis by regulating fibroblasts via HIF-1α	53
Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies	53
Enhancer reprogramming: critical roles in cancer and promising therapeutic strategies	53
The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma	53
Polyploidy mitigates the impact of DNA damage while simultaneously bearing its burden	53
Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis	52
Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor	52
Mechanisms of ferroptosis and targeted therapeutic approaches in urological malignancies	52
Tp53 haploinsufficiency is involved in hotspot mutations and cytoskeletal remodeling in gefitinib-induced drug-resistant EGFRL858R-lung cancer mice	52
NEDD8-conjugating enzyme E2s: critical targets for cancer therapy	51
MEKK3 bridges gut-brain communication and cerebral cavernous malformation pathogenesis	51
Oleanolic acid combined with aspirin plays antitumor roles in colorectal cancer via the Akt/NFκB/IκBα/COX2 pathway	51
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A	50
BAP1 inactivation promotes lactate production by leveraging the subcellular localization of LDHA in melanoma	50
Nesprin-2 contains BH3-like motifs that can promote cell death	49
PGD2 displays distinct effects in diffuse large B-cell lymphoma depending on different concentrations	49
Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target	49
Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response	48
Increased efficacy of PARP inhibitors against cisplatin-sensitive and -resistant ovarian cancer cells mediated via ATR and ATM inhibition	48
Rapid iPSC-derived neuromuscular junction model uncovers motor neuron dominance in amyotrophic lateral sclerosis cytopathy	48
DSE inhibits melanoma progression by regulating tumor immune cell infiltration and VCAN	48
An evolutionarily conserved role for separase in the regulation of nuclear lamins	48
Gastrointestinal acute radiation syndrome: current knowledge and perspectives	48
Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA	48
Standardized assays to monitor drug sensitivity in hematologic cancers	47
Metal-polyphenol-network coated R612F nanoparticles reduce drug resistance in hepatocellular carcinoma by inhibiting stress granules	47
Deletion in RMST lncRNA impairs hypothalamic neuronal development in a human stem cell-based model of Kallmann Syndrome	46
ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer	46
IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure	46
Circular RNA hsa_circ_0001846 facilitates the malignant behaviors of pancreatic cancer by sponging miR-204-3p and upregulating KRAS expression	45
Correction: Tim-3 protects against cisplatin nephrotoxicity by inhibiting NF-κB-mediated inflammation	45
Developing novel Lin28 inhibitors by computer aided drug design	45
LEADR, a p63 target, dampens interferon signalling in bladder cancer	45
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750	44
CAPG is a novel biomarker for early gastric cancer and is involved in the Wnt/β-catenin signaling pathway	44
A positive feedback loop between TKT and c-Myc drives TACE resistance in hepatocellular carcinoma	44
Fatty acid amide hydrolase drives adult mammary gland development by promoting luminal cell differentiation	44
FGFR inhibition as a new therapeutic strategy to sensitize glioblastoma stem cells to tumor treating fields	44
GSDMD deficiency attenuates BPD by suppressing macrophage pyroptosis and promoting M2 polarization	44
Rafoxanide disrupts mitochondrial homeostasis through VDAC1 modulation in colorectal cancer cells	44
Targeting cell death in Crohn’s disease: from mechanisms to medicines	43
N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling	43
Overcoming apoptotic resistance afforded by Bcl-2 in lymphoid tumor cells: a critical role for dexamethasone	43
MED15 is upregulated by HIF-2α and promotes proliferation and metastasis in clear cell renal cell carcinoma via activation of SREBP-dependent fatty acid synthesis	43
PPA1 promotes oxidative phosphorylation and malignant progression of colorectal cancer under glucose restriction via AMPK/ULK1/FUNDC1-mediated mitophagy	42
Multidimensional regulatory roles and therapeutic applications of SRSF7 in cancer	42
The potential role of hydrogen sulfide in cancer cell apoptosis	42
High-throughput strategy for targeting MDM2 in uveal melanoma to reverse radiation therapy resistance	42
Different types of cell death and their shift in shaping disease	42

NAT10 promotes gallbladder cancer progression by remodeling cholesterol metabolism via PCSK9 mRNA acetylation	42
RASAL2 regulates the cell cycle and cyclin D1 expression through PI3K/AKT signalling in prostate tumorigenesis	42
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner	42
Anti-CCL2 therapy reduces oxygen toxicity to the immature lung	42
Misregulated alternative splicing in endometriosis: a role for aberrant mRNA variants in endometriotic cell growth	41
CREB5 promotes nodal metastasis of cervical cancer by regulation of APLN-induced lymphangiogenesis	41
hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM2	41
Nicotinamide N-methyltransferase as a therapeutic target in taxane-resistant castration-resistant prostate cancer	41
Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease	41
Mechanical stiffness promotes skin fibrosis through Piezo1-mediated arginine and proline metabolism	41
Organoids and organs-on-chips: insights into predicting the efficacy of systemic treatment in colorectal cancer	40
Inhibition of acetyl-CoA carboxylase impaired tubulin palmitoylation and induced spindle abnormalities	40
Uveitic glaucoma-like features in Yap conditional knockout mice	40
Downregulation of KLF10 contributes to the regeneration of survived renal tubular cells in cisplatin-induced acute kidney injury via ZBTB7A-KLF10-PTEN axis	40
UCK2 promotes intrahepatic cholangiocarcinoma progression and desensitizes cisplatin treatment by PI3K/AKT/mTOR/autophagic axis	40
LIGHT deficiency attenuates acute kidney disease development in an in vivo experimental renal ischemia and reperfusion injury model	40
Circular RNAs and mammalian follicular development: current insights and future prospects—an updated review	39
USP18 deubiquitinates and stabilizes SOX9 to promote the stemness and malignant progression of glioblastoma	39
Integrated stress response is involved in the 24(S)-hydroxycholesterol-induced unconventional cell death mechanism	38
Hypoxia promotes progression of cervical cancer by modulating the ATXN3-enhanced P53 stability or STAT5 phosphorylation	38
Myeloid PTEN loss affects the therapeutic response by promoting stress granule assembly and impairing phagocytosis by macrophages in breast cancer	38
TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination	38
Interplay between genes and social environment: from epigenetics to precision medicine	38
The LTB4-BLT1 axis attenuates influenza-induced lung inflammation by suppressing NLRP3 activation	38
ERBB3 influences the ferroptosis pathway via modulation of lipid peroxidation and GSH synthesis in gastric cancer	38
NRG1/PDGFC loop between fibroblasts and cancer cells drives paclitaxel resistance via ferroptosis suppression in breast cancer	38
hnRNP A1 inhibits colorectal cancer tumorigenesis and progression by regulating fatty acid metabolism and RNA stability	38
Maternal linoleic acid-rich diet ameliorates bilirubin neurotoxicity in offspring mice	38
Organoid modeling meets cancers of female reproductive tract	37
Mesenchymal stem cell-derived extracellular vesicles transfer miR-598 to inhibit the growth and metastasis of non-small-cell lung cancer by targeting THBS2	37
Role of Sox9 in BPD and its effects on the Wnt/β-catenin pathway and AEC-II differentiation	37
MiR-146a-5p deficiency in extracellular vesicles of glioma-associated macrophages promotes epithelial-mesenchymal transition through the NF-κB signaling pathway	37
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis	37
CaMKIV mediates spine growth deficiency of hippocampal neurons by regulation of EGR3/BDNF signal axis in congenital hypothyroidism	36
Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species	36
Targeting the redox-programmed cell death axis in breast cancer: from molecular mechanisms to therapeutic resistance	36
Antisense lncRNA NNT-AS1 promoted esophageal squamous cell carcinoma progression by regulating its sense gene NNT expression	36
Decoding MUC1 and AR axis in a radiation-induced neuroendocrine prostate cancer cell-subpopulation unveils novel therapeutic targets	36
Bacterial protein-oleate complexes induce ferroptosis-like cell death in colorectal cancer cells by disrupting cell membranes and inhibiting the β-catenin-GPX4 axis	35
Nucleophosmin 1 cooperates with BRD4 to facilitate c-Myc transcription to promote prostate cancer progression	35
RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription	35
The miRNA and PD-1/PD-L1 signaling axis: an arsenal of immunotherapeutic targets against lung cancer	35
TAZ promotes osteogenic differentiation of mesenchymal stem cells line C3H10T1/2, murine multi-lineage cells lines C2C12, and MEFs induced by BMP9	35
CRISPR/Cas9 screening identifies SUV39H2 as a key regulator of oHSV-1 resistance in oral squamous cell carcinoma	35
Lysophosphatidic acid exerts protective effects on HEI-OC1 cells against cytotoxicity of cisplatin by decreasing apoptosis, excessive autophagy, and accumulation of ROS	35
NOXA exacerbates endoplasmic-reticulum-stress-induced intervertebral disc degeneration by activating apoptosis and ECM degradation	35
Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer	35
NAT10-mediated upregulation of GAS5 facilitates immune cell infiltration in non-small cell lung cancer via the MYBBP1A-p53/IRF1/type I interferon signaling axis	35
The trigger for pancreatic disease: NLRP3 inflammasome	35
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway	35
Tissue-resident Klebsiella quasipneumoniae contributes to progression of idiopathic pulmonary fibrosis by triggering macrophages mitophagy in mice	34
PLK1 inhibition promotes apoptosis and DNA damage in glioma stem cells by regulating the nuclear translocation of YBX1	34
Long noncoding RNA profiling unveils LINC00960 as unfavorable prognostic biomarker promoting triple negative breast cancer progression	34
Aging aggravated liver ischemia and reperfusion injury by promoting oxidized mtDNA mediated-macrophage pyroptosis through acetylated MCU-dependent calcium uptake	34
Hypoxia-induced epigenetic regulation of miR-485-3p promotes stemness and chemoresistance in pancreatic ductal adenocarcinoma via SLC7A11-mediated ferroptosis	34
Novel mechanism of neuronal hypoxia response: HIF-1α/STOML2 mediated PINK1-dependent mitophagy activation against neuronal injury	34
SOX2 and OCT4 mediate radiation and drug resistance in pancreatic tumor organoids	34
AMPK is dispensable for physiological podocyte and glomerular functions but prevents glomerular fibrosis in experimental diabetes	34
Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4	34
NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma	34
Synergistic mechanism between the endoplasmic reticulum and mitochondria and their crosstalk with other organelles	33
Serum amyloid protein A in inflammatory bowel disease: from bench to bedside	33
Insights on the crosstalk among different cell death mechanisms	33
Endothelial mechanosensitive transcription factor BHLHE40 induced by Piezo1 suppresses endothelial ferroptosis and inflammation via SLC7A11	33
A bibliometric analysis of ferroptosis, necroptosis, pyroptosis, and cuproptosis in cancer from 2012 to 2022	33
4-aminopyridine attenuates inflammation and apoptosis and increases angiogenesis to promote skin regeneration following a burn injury in mice	33
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis	33
AMPK-induced novel phosphorylation of RUNX1 inhibits STAT3 activation and overcome imatinib resistance in chronic myelogenous leukemia (CML) subjects	33
Ferroptosis: Emerging mechanisms, biological function, and therapeutic potential in cancer and inflammation	33
N6-methyladenosine (m6A) writer METTL5 represses the ferroptosis and antitumor immunity of gastric cancer	33
Exploiting dysregulated iron homeostasis to eradicate persistent high-grade serous ovarian cancer	33
USP5 promotes glycolysis of fibroblast-like synoviocytes by stabilizing the METTL14/m6A/GLUT1 axis in rheumatoid arthritis	32
Saikosaponin‑D triggers cancer cell death by targeting the PIM1/c-Myc axis to reprogram oncogenic alternative splicing	32
A comprehensive review of human trophoblast fusion models: recent developments and challenges	32
Effects of astrocytic PKM2 gene deletion on neuronal death following traumatic brain injury	32
CERS6 promotes esophageal squamous cell carcinoma proliferation by increasing the stability of RPN1	32
Diabetes impairs fracture healing through Foxo1 mediated disruption of ciliogenesis	32
Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2	32
PARP4 deficiency enhances sensitivity to ATM inhibitor by impairing DNA damage repair in melanoma	32
A testis-specific lncRNA functions as a post-transcriptional regulator of MDM2 and stimulates apoptosis of testicular germ cell tumor cells	31
Cold-induced hepatocyte-derived exosomes activate brown adipose thermogenesis via miR-293-5p-mediated transcriptional reprogramming	31
The glycolytic enzyme PFKFB3 alleviates DNA damage and chondrocyte senescence in osteoarthritis	31
MEKK4-mediated Phosphorylation of HOXA10 at Threonine 362 facilitates embryo adhesion to the endometrial epithelium	31
The monkeypox virus suppresses autophagy by modulating Rubicon expression	31
KDM4C silencing inhibits cell migration and enhances radiosensitivity by inducing CXCL2 transcription in hepatocellular carcinoma	30
Heterogeneity of cancer-associated fibroblasts in head and neck squamous cell carcinoma: opportunities and challenges	30
Reformed islets: a long-term primary cell platform for exploring mouse and human islet biology	30
A miR-34a-guided, tRNAiMet-derived, piR_019752-like fragment (tRiMetF31) suppresses migration and angiogenesis of breast cancer cells via targeting PFKFB3	30
The fungal peptide toxin candidalysin induces distinct membrane repair mechanisms compared to bacterial pore-forming toxins	30
Differentiated SH-SY5Y cells exhibit neuronal features but lack synaptic maturity	30
Mitochondrial reactive oxygen species promote cancer metastasis and tumor microenvironment immunosuppression through gasdermin D	30
Deciphering the STAT3-PXN positive feedback loop in GBM, IDH-wildtype: transcriptional regulation and inhibition of YB-1 ubiquitination	30
NRG1 knockdown rescues PV interneuron GABAergic maturation deficits and schizophrenia behaviors in fetal growth restriction mice	30
Emerging roles of ferroptosis-related miRNAs in tumor metastasis	30
PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling	30