Cell Death Discovery

Papers
(The TQCC of Cell Death Discovery is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1273
Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis260
Retraction Note to: Inhibition of TGF-β repairs spinal cord injury by attenuating EphrinB2 expressing through inducing miR-484 from fibroblast196
Exploring necroptosis: mechanistic analysis and antitumor potential of nanomaterials188
Therapeutic targeting of STING-IL6/STAT3 axis to inhibit osteoclastic niche formation and breast cancer bone metastasis184
Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis177
GILT stabilizes cofilin to promote the metastasis of prostate cancer170
RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation167
Radiobiological characterisation of a 28 MeV proton beam delivered by the MC-40 cyclotron132
Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model125
STING agonists trigger monocyte death via apoptosis, pyroptosis, caspase-8 activation and mitochondrial dysfunction124
Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion124
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH121
N6-methyladenosine: a key regulator in ocular disease mechanisms and treatment121
USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression108
Matrix metalloproteinase-10 promotes kidney fibrosis by transactivating β-catenin signaling107
Senescence as a dictator of patient outcomes and therapeutic efficacies in human gastric cancer107
Targeting NAD+: is it a common strategy to delay heart aging?104
The role of ankyrin repeat-containing proteins in epigenetic and transcriptional regulation104
Hippo pathway and NLRP3-driven NETosis in macrophages: Mechanisms of viral pneumoniaaggravation101
LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism100
Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis99
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics97
Metformin protects retinal ganglion cells in a preclinical model of retinal ischemia/reperfusion injury and stabilizes visual field in diabetic patients with glaucoma96
PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway95
LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma95
ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues95
An mTOR and DNA-PK dual inhibitor CC-115 hinders non-small cell lung cancer cell growth92
Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma91
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death88
Smoking-induced microbial dysbiosis: a key driver of systemic diseases and emerging therapeutic opportunities88
Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc4288
AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury86
The plasticity of epithelial cells and its potential in the induced differentiation of gastric cancer86
Targeting mitochondrial autophagy for anti-aging84
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression84
Absence of Rnf126 causes male infertility with multiple morphological abnormalities of the sperm flagella83
Mitochondrial metabolic reprogramming in colorectal cancer: mechanisms of resistance and future clinical interventions82
Lipids associated with autophagy: mechanisms and therapeutic targets81
CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma79
Diverse functions of NLRP3 inflammasome in PANoptosis and diseases79
Stem cell-derived intestinal organoids: a novel modality for IBD77
USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target75
AXL tyrosine kinase inhibitor TP-0903 induces ROS trigger neuroblastoma cell apoptosis via targeting the miR-335-3p/DKK1 expression75
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer74
N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction71
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI71
The pathological role of damaged organelles in renal tubular epithelial cells in the progression of acute kidney injury70
Exosomal circRNAs: key modulators in breast cancer progression70
The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer69
Vascular smooth muscle cell metabolic reprogramming and phenotypic remodeling in atherosclerosis69
DUB3/KLF4 combats tumor growth and chemoresistance in hepatocellular carcinoma69
MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP168
IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL1068
New insights into constitutive neutrophil death68
Tissue microenvironment induces tissue specificity of ILC265
Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis65
POLE2 promotes osteosarcoma progression by enhancing the stability of CD4464
Cellular senescence of renal tubular epithelial cells in acute kidney injury64
CD95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a CD95 ligand-independent manner64
Long non-coding RNA-encoded micropeptides: functions, mechanisms and implications64
Correction: Autophagy in hepatic ischemia–reperfusion injury62
BRD7 suppresses tumor chemosensitivity to CHK1 inhibitors by inhibiting USP1-mediated deubiquitination of CHK161
TRPS1 regulates the opposite effect of progesterone via RANKL in endometrial carcinoma and breast carcinoma61
Long non-coding RNA MAFG-AS1 promotes proliferation and metastasis of breast cancer by modulating STC2 pathway60
The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma60
JMJD2C mediates the MDM2/p53/IL5RA axis to promote CDDP resistance in uveal melanoma60
Exosomal miR-122-5p from tubular cells ameliorates renal interstitial fibrosis by regulating fibroblasts via HIF-1α59
Hexamethylene amiloride induces lysosome-mediated cell death in multiple myeloma through transcription factor E359
APOE4 promotes nigral tau hyperphosphorylation through cholesterol in atherosclerosis59
Thapsigargin triggers a non-apoptotic, caspase-independent programmed cell death in basophilic leukaemia cells59
Fexofenadine protects against osteoarthritis by targeting Smad2 and STAT1 to enhance anabolism and binding cPLA2 to inhibit catabolism59
Loss of Ripk3 attenuated neutrophil accumulation in a lipopolysaccharide-induced zebrafish inflammatory model58
Exploring the metabolic signaling network of GFPT in cancer58
From mechanisms to markers: role of pyroptosis in revolutionizing thyroid cancer care57
Modulation of stress granules by lobeline increases cell death in hypoxia and impacts the ability of glioblastoma cells to secrete extracellular vesicles57
MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling57
Epirubicin induces cardiotoxicity through disrupting ATP6V0A2-dependent lysosomal acidification and triggering ferroptosis in cardiomyocytes56
Inhibition of TGF-beta signaling protects from alpha-synuclein induced toxicity56
Long noncoding RNA SNHG1 silencing accelerates hepatocyte-like cell differentiation of bone marrow-derived mesenchymal stem cells to alleviate cirrhosis via the microRNA-15a/SMURF1/UVRAG axis56
Repurposing proteasome inhibitors for improved treatment of triple-negative breast cancer56
Differential effects of HDAC inhibitors in the RhoI255d mouse model for autosomal dominant retinitis pigmentosa55
Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway55
Neddylation inhibition induces DNA double-strand breaks, hampering tumor growth in vivo, and promotes radiosensitivity in PAX3–FOXO1 rhabdomyosarcoma55
COVID-19 related neurological manifestations in Parkinson’s disease: has ferroptosis been a suspect?55
LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins54
Heat shock protein 90α reduces CD8+ T cell exhaustion in acute lung injury induced by lipopolysaccharide54
LncRNA XIST accelerates burn wound healing by promoting M2 macrophage polarization through targeting IL-33 via miR-19b54
Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies54
MYC inhibition reprograms tumor immune microenvironment by recruiting T lymphocytes and activating the CD40/CD40L system in osteosarcoma53
NRF2 transcriptionally regulates Caspase-11 expression to activate HMGB1 release by Autophagy-deficient hepatocytes53
Immunotherapy for autoimmune encephalitis53
VDR and deubiquitination control neuronal oxidative stress and microglial inflammation in Parkinson’s disease53
YAP is required for prostate development, regeneration, and prostate stem cell function52
MiR-134-5p inhibits the malignant phenotypes of osteosarcoma via ITGB1/MMP2/PI3K/Akt pathway52
Fosinopril mediates antitumor efficacy by inducing GSDME-dependent pyroptosis in NSCLC52
Methylation in cornea and corneal diseases: a systematic review52
The EZH2-H3K27me3 axis modulates aberrant transcription and apoptosis in cyclophosphamide-induced ovarian granulosa cell injury51
Polyploidy mitigates the impact of DNA damage while simultaneously bearing its burden50
Targeting Txnip-mediated metabolic reprogramming has therapeutic potential for osteoarthritis50
Circadian rhythm regulates the function of immune cells and participates in the development of tumors49
Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress49
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF449
Comprehensive analysis of cellular metrics: From proliferation to mitochondrial membrane potential and cell death in a single sample48
Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation47
LncRNA in tumorigenesis of non-small-cell lung cancer: From bench to bedside47
Metabolic reprogramming in melanoma therapy47
Gemcitabine elaidate and ONC201 combination therapy for inhibiting pancreatic cancer in a KRAS mutated syngeneic mouse model47
IL-8 activates fibroblasts to promote the invasion of HNSCC cells via STAT3-MMP147
Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer46
Enhancer reprogramming: critical roles in cancer and promising therapeutic strategies46
Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor45
DSE inhibits melanoma progression by regulating tumor immune cell infiltration and VCAN45
Rapid iPSC-derived neuromuscular junction model uncovers motor neuron dominance in amyotrophic lateral sclerosis cytopathy45
CREB5 promotes nodal metastasis of cervical cancer by regulation of APLN-induced lymphangiogenesis44
LIGHT deficiency attenuates acute kidney disease development in an in vivo experimental renal ischemia and reperfusion injury model44
PGD2 displays distinct effects in diffuse large B-cell lymphoma depending on different concentrations44
Increased efficacy of PARP inhibitors against cisplatin-sensitive and -resistant ovarian cancer cells mediated via ATR and ATM inhibition44
GSDMD deficiency attenuates BPD by suppressing macrophage pyroptosis and promoting M2 polarization43
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner43
SOX17-mediated MALAT1-miR-199a-HIF1α axis confers sensitivity in esophageal squamous cell carcinoma cells to radiotherapy43
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A43
Correction to: Microfluidic deep mutational scanning of the human executioner caspases reveals differences in structure and regulation42
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF75042
An evolutionarily conserved role for separase in the regulation of nuclear lamins42
RETRACTED ARTICLE: MIR600HG sponges miR-125a-5p to regulate glycometabolism and cisplatin resistance of oral squamous cell carcinoma cells via mediating RNF4442
PPA1 promotes oxidative phosphorylation and malignant progression of colorectal cancer under glucose restriction via AMPK/ULK1/FUNDC1-mediated mitophagy41
N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling41
NEDD8-conjugating enzyme E2s: critical targets for cancer therapy41
Correction: Tim-3 protects against cisplatin nephrotoxicity by inhibiting NF-κB-mediated inflammation41
Different types of cell death and their shift in shaping disease41
CAPG is a novel biomarker for early gastric cancer and is involved in the Wnt/β-catenin signaling pathway41
UCK2 promotes intrahepatic cholangiocarcinoma progression and desensitizes cisplatin treatment by PI3K/AKT/mTOR/autophagic axis41
hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM241
Anti-CCL2 therapy reduces oxygen toxicity to the immature lung40
Multidimensional regulatory roles and therapeutic applications of SRSF7 in cancer40
Mechanisms of ferroptosis and targeted therapeutic approaches in urological malignancies40
LncRNA LYPLAL1-DT screening from type 2 diabetes with macrovascular complication contributes protective effects on human umbilical vein endothelial cells via regulating the miR-204-5p/SIRT1 axis40
Standardized assays to monitor drug sensitivity in hematologic cancers40
LEADR, a p63 target, dampens interferon signalling in bladder cancer39
Nesprin-2 contains BH3-like motifs that can promote cell death39
Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA39
FGFR inhibition as a new therapeutic strategy to sensitize glioblastoma stem cells to tumor treating fields39
Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease39
Metal-polyphenol-network coated R612F nanoparticles reduce drug resistance in hepatocellular carcinoma by inhibiting stress granules39
IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure39
Fatty acid amide hydrolase drives adult mammary gland development by promoting luminal cell differentiation39
RASAL2 regulates the cell cycle and cyclin D1 expression through PI3K/AKT signalling in prostate tumorigenesis38
Tp53 haploinsufficiency is involved in hotspot mutations and cytoskeletal remodeling in gefitinib-induced drug-resistant EGFRL858R-lung cancer mice38
Mechanical stiffness promotes skin fibrosis through Piezo1-mediated arginine and proline metabolism38
BAP1 inactivation promotes lactate production by leveraging the subcellular localization of LDHA in melanoma38
Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target38
MED15 is upregulated by HIF-2α and promotes proliferation and metastasis in clear cell renal cell carcinoma via activation of SREBP-dependent fatty acid synthesis38
Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response38
Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis38
Circular RNA hsa_circ_0001846 facilitates the malignant behaviors of pancreatic cancer by sponging miR-204-3p and upregulating KRAS expression38
Organoids and organs-on-chips: insights into predicting the efficacy of systemic treatment in colorectal cancer37
Overcoming apoptotic resistance afforded by Bcl-2 in lymphoid tumor cells: a critical role for dexamethasone37
Developing novel Lin28 inhibitors by computer aided drug design37
Oleanolic acid combined with aspirin plays antitumor roles in colorectal cancer via the Akt/NFκB/IκBα/COX2 pathway37
The potential role of hydrogen sulfide in cancer cell apoptosis37
CaMKIV mediates spine growth deficiency of hippocampal neurons by regulation of EGR3/BDNF signal axis in congenital hypothyroidism36
Uveitic glaucoma-like features in Yap conditional knockout mice36
USP18 deubiquitinates and stabilizes SOX9 to promote the stemness and malignant progression of glioblastoma36
Deletion in RMST lncRNA impairs hypothalamic neuronal development in a human stem cell-based model of Kallmann Syndrome36
Exploiting dysregulated iron homeostasis to eradicate persistent high-grade serous ovarian cancer36
Correction: Heparanase promotes endothelial-to-mesenchymal transition in diabetic glomerular endothelial cells through mediating ERK signaling36
Nucleophosmin 1 cooperates with BRD4 to facilitate c-Myc transcription to promote prostate cancer progression36
ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer36
Maternal linoleic acid-rich diet ameliorates bilirubin neurotoxicity in offspring mice36
Downregulation of KLF10 contributes to the regeneration of survived renal tubular cells in cisplatin-induced acute kidney injury via ZBTB7A-KLF10-PTEN axis36
Integrated stress response is involved in the 24(S)-hydroxycholesterol-induced unconventional cell death mechanism36
Author Correction: Gelatine nanostructured lipid carrier encapsulated FGF15 inhibits autophagy and improves recovery in spinal cord injury36
Gastrointestinal acute radiation syndrome: current knowledge and perspectives36
Targeting the redox-programmed cell death axis in breast cancer: from molecular mechanisms to therapeutic resistance35
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis35
Saikosaponin‑D triggers cancer cell death by targeting the PIM1/c-Myc axis to reprogram oncogenic alternative splicing35
Interplay between genes and social environment: from epigenetics to precision medicine35
Hsa_circ_0007967 promotes gastric cancer proliferation through the miR-411-5p/MAML3 axis34
TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination34
NRG1/PDGFC loop between fibroblasts and cancer cells drives paclitaxel resistance via ferroptosis suppression in breast cancer34
Circular RNAs and mammalian follicular development: current insights and future prospects—an updated review34
The LTB4-BLT1 axis attenuates influenza-induced lung inflammation by suppressing NLRP3 activation34
Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway33
NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma33
Synergistic mechanism between the endoplasmic reticulum and mitochondria and their crosstalk with other organelles33
Long noncoding RNA profiling unveils LINC00960 as unfavorable prognostic biomarker promoting triple negative breast cancer progression33
TAZ promotes osteogenic differentiation of mesenchymal stem cells line C3H10T1/2, murine multi-lineage cells lines C2C12, and MEFs induced by BMP933
N6-methyladenosine (m6A) writer METTL5 represses the ferroptosis and antitumor immunity of gastric cancer33
Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-233
circ_0004140 promotes LUAD tumor progression and immune resistance through circ_0004140/miR-1184/CCL22 axis33
CERS6 promotes esophageal squamous cell carcinoma proliferation by increasing the stability of RPN133
Organoid modeling meets cancers of female reproductive tract33
METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism33
Antisense lncRNA NNT-AS1 promoted esophageal squamous cell carcinoma progression by regulating its sense gene NNT expression33
Inhibition of acetyl-CoA carboxylase impaired tubulin palmitoylation and induced spindle abnormalities33
Myeloid PTEN loss affects the therapeutic response by promoting stress granule assembly and impairing phagocytosis by macrophages in breast cancer32
Hypoxia-induced epigenetic regulation of miR-485-3p promotes stemness and chemoresistance in pancreatic ductal adenocarcinoma via SLC7A11-mediated ferroptosis32
MiR-146a-5p deficiency in extracellular vesicles of glioma-associated macrophages promotes epithelial-mesenchymal transition through the NF-κB signaling pathway32
Mesenchymal stem cell-derived extracellular vesicles transfer miR-598 to inhibit the growth and metastasis of non-small-cell lung cancer by targeting THBS232
Decoding MUC1 and AR axis in a radiation-induced neuroendocrine prostate cancer cell-subpopulation unveils novel therapeutic targets32
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis32
NOXA exacerbates endoplasmic-reticulum-stress-induced intervertebral disc degeneration by activating apoptosis and ECM degradation32
Tumor-derived extracellular vesicles inhibit HGF/c-Met and EGF/EGFR pathways to accelerate the radiosensitivity of nasopharyngeal carcinoma cells via microRNA-142-5p delivery32
Aging aggravated liver ischemia and reperfusion injury by promoting oxidized mtDNA mediated-macrophage pyroptosis through acetylated MCU-dependent calcium uptake32
RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription32
Role of Sox9 in BPD and its effects on the Wnt/β-catenin pathway and AEC-II differentiation32
ERBB3 influences the ferroptosis pathway via modulation of lipid peroxidation and GSH synthesis in gastric cancer31
Serum amyloid protein A in inflammatory bowel disease: from bench to bedside31
SOX2 and OCT4 mediate radiation and drug resistance in pancreatic tumor organoids31
CRISPR/Cas9 screening identifies SUV39H2 as a key regulator of oHSV-1 resistance in oral squamous cell carcinoma31
Lysophosphatidic acid exerts protective effects on HEI-OC1 cells against cytotoxicity of cisplatin by decreasing apoptosis, excessive autophagy, and accumulation of ROS31
hnRNP A1 inhibits colorectal cancer tumorigenesis and progression by regulating fatty acid metabolism and RNA stability31
Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer31
High-dose-androgen-induced autophagic cell death to suppress the Enzalutamide-resistant prostate cancer growth via altering the circRNA-BCL2/miRNA-198/AMBRA1 signaling31
Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species31
Tissue-resident Klebsiella quasipneumoniae contributes to progression of idiopathic pulmonary fibrosis by triggering macrophages mitophagy in mice31
Endothelial mechanosensitive transcription factor BHLHE40 induced by Piezo1 suppresses endothelial ferroptosis and inflammation via SLC7A1131
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway30
PARP4 deficiency enhances sensitivity to ATM inhibitor by impairing DNA damage repair in melanoma30
Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD430
A comprehensive review of human trophoblast fusion models: recent developments and challenges30
UBAP2L promotes gastric cancer metastasis by activating NF-κB through PI3K/AKT pathway30
PLK1 inhibition promotes apoptosis and DNA damage in glioma stem cells by regulating the nuclear translocation of YBX130
4-aminopyridine attenuates inflammation and apoptosis and increases angiogenesis to promote skin regeneration following a burn injury in mice30
The cancer/testis antigen HORMAD1 mediates epithelial–mesenchymal transition to promote tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway in lung cancer30
AMPK-induced novel phosphorylation of RUNX1 inhibits STAT3 activation and overcome imatinib resistance in chronic myelogenous leukemia (CML) subjects30
Insights on the crosstalk among different cell death mechanisms30
NAT10-mediated upregulation of GAS5 facilitates immune cell infiltration in non-small cell lung cancer via the MYBBP1A-p53/IRF1/type I interferon signaling axis30
The miRNA and PD-1/PD-L1 signaling axis: an arsenal of immunotherapeutic targets against lung cancer29
Human myeloid differentiation by BMP4 signaling through the VDR pathway in acute myeloid leukemia29
Ferroptosis: Emerging mechanisms, biological function, and therapeutic potential in cancer and inflammation29
Diabetes impairs fracture healing through Foxo1 mediated disruption of ciliogenesis29
A miR-34a-guided, tRNAiMet-derived, piR_019752-like fragment (tRiMetF31) suppresses migration and angiogenesis of breast cancer cells via targeting PFKFB329
A bibliometric analysis of ferroptosis, necroptosis, pyroptosis, and cuproptosis in cancer from 2012 to 202229
The trigger for pancreatic disease: NLRP3 inflammasome29
RBM17 promotes hepatocellular carcinoma progression by regulating lipid metabolism and immune microenvironment: implications for therapeutic targeting28
Correction: Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space28
Cuproptosis and cuproptosis-related cell death and genes: mechanistic links to spermatogenic cell death28
EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma28
Reformed islets: a long-term primary cell platform for exploring mouse and human islet biology28
Rsk2 inhibition induces an aneuploid post-mitotic arrest of cell cycle progression in osteosarcoma cells28
NCOA7 inhibits renal cancer progression by inducing autophagy and lipid metabolism through V-ATPase interaction28
Dysregulation of SNX1-retromer axis in pharmacogenetic models of Parkinson’s disease28
USP5 promotes glycolysis of fibroblast-like synoviocytes by stabilizing the METTL14/m6A/GLUT1 axis in rheumatoid arthritis28
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis28
Targeting iron regulatory protein 2 (IRP2) to disrupt iron metabolism enhances radiosensitivity through mitochondrial dysfunction in breast cancer cells28
Carfilzomib relieves pancreatitis-initiated pancreatic ductal adenocarcinoma by inhibiting high-temperature requirement protein A128
Novel prognostic marker LINC00205 promotes tumorigenesis and metastasis by competitively suppressing miRNA-26a in gastric cancer28
Gas6 in chronic liver disease—a novel blood-based biomarker for liver fibrosis28
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