Cell Death Discovery

Article	Citations
USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression	238
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1	185
Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis	178
Retraction Note to: Inhibition of TGF-β repairs spinal cord injury by attenuating EphrinB2 expressing through inducing miR-484 from fibroblast	167
N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction	166
Exosomal circRNAs: key modulators in breast cancer progression	164
Matrix metalloproteinase-10 promotes kidney fibrosis by transactivating β-catenin signaling	155
POLE2 promotes osteosarcoma progression by enhancing the stability of CD44	152
An mTOR and DNA-PK dual inhibitor CC-115 hinders non-small cell lung cancer cell growth	120
AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury	115
Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc42	113
MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1	110
Long non-coding RNA-encoded micropeptides: functions, mechanisms and implications	110
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death	109
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI	106
Stem cell-derived intestinal organoids: a novel modality for IBD	100
ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues	100
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer	97
CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma	92
AXL tyrosine kinase inhibitor TP-0903 induces ROS trigger neuroblastoma cell apoptosis via targeting the miR-335-3p/DKK1 expression	91
Hippo pathway and NLRP3-driven NETosis in macrophages: Mechanisms of viral pneumoniaaggravation	91
RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation	89
Radiobiological characterisation of a 28 MeV proton beam delivered by the MC-40 cyclotron	88
Mitochondrial metabolic reprogramming in colorectal cancer: mechanisms of resistance and future clinical interventions	85
LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism	85

The plasticity of epithelial cells and its potential in the induced differentiation of gastric cancer	84
The role of ankyrin repeat-containing proteins in epigenetic and transcriptional regulation	83
Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model	83
LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma	83
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics	81
Absence of Rnf126 causes male infertility with multiple morphological abnormalities of the sperm flagella	80
Targeting NAD+: is it a common strategy to delay heart aging?	80
Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis	80
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH	79
Tissue microenvironment induces tissue specificity of ILC2	78
Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma	78
Cellular senescence of renal tubular epithelial cells in acute kidney injury	77
Therapeutic targeting of STING-IL6/STAT3 axis to inhibit osteoclastic niche formation and breast cancer bone metastasis	76
Lipids associated with autophagy: mechanisms and therapeutic targets	76
PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway	76
DUB3/KLF4 combats tumor growth and chemoresistance in hepatocellular carcinoma	74
Senescence as a dictator of patient outcomes and therapeutic efficacies in human gastric cancer	72
Diverse functions of NLRP3 inflammasome in PANoptosis and diseases	71
Exploring necroptosis: mechanistic analysis and antitumor potential of nanomaterials	69
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression	68
STING agonists trigger monocyte death via apoptosis, pyroptosis, caspase-8 activation and mitochondrial dysfunction	67
New insights into constitutive neutrophil death	67
Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis	66
The pathological role of damaged organelles in renal tubular epithelial cells in the progression of acute kidney injury	66
USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target	66
Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion	65
Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis	64
GILT stabilizes cofilin to promote the metastasis of prostate cancer	64
The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer	63
IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL10	63
MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling	62
Targeting Txnip-mediated metabolic reprogramming has therapeutic potential for osteoarthritis	62
CD95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a CD95 ligand-independent manner	62
NRF2 transcriptionally regulates Caspase-11 expression to activate HMGB1 release by Autophagy-deficient hepatocytes	58
Exploring the metabolic signaling network of GFPT in cancer	57
The EZH2-H3K27me3 axis modulates aberrant transcription and apoptosis in cyclophosphamide-induced ovarian granulosa cell injury	56
JMJD2C mediates the MDM2/p53/IL5RA axis to promote CDDP resistance in uveal melanoma	56
Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation	55
Correction: Autophagy in hepatic ischemia–reperfusion injury	55
Hexamethylene amiloride induces lysosome-mediated cell death in multiple myeloma through transcription factor E3	55
COVID-19 related neurological manifestations in Parkinson’s disease: has ferroptosis been a suspect?	55
Long noncoding RNA SNHG1 silencing accelerates hepatocyte-like cell differentiation of bone marrow-derived mesenchymal stem cells to alleviate cirrhosis via the microRNA-15a/SMURF1/UVRAG axis	55
TRPS1 regulates the opposite effect of progesterone via RANKL in endometrial carcinoma and breast carcinoma	55
BRD7 suppresses tumor chemosensitivity to CHK1 inhibitors by inhibiting USP1-mediated deubiquitination of CHK1	55
VDR and deubiquitination control neuronal oxidative stress and microglial inflammation in Parkinson’s disease	54
LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins	54
Polyploidy mitigates the impact of DNA damage while simultaneously bearing its burden	54
The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma	54
Modulation of stress granules by lobeline increases cell death in hypoxia and impacts the ability of glioblastoma cells to secrete extracellular vesicles	53
MYC inhibition reprograms tumor immune microenvironment by recruiting T lymphocytes and activating the CD40/CD40L system in osteosarcoma	53

Thapsigargin triggers a non-apoptotic, caspase-independent programmed cell death in basophilic leukaemia cells	53
Epirubicin induces cardiotoxicity through disrupting ATP6V0A2-dependent lysosomal acidification and triggering ferroptosis in cardiomyocytes	53
Biased activation of β2-AR/Gi/GRK2 signal pathway attenuated β1-AR sustained activation induced by β1-adrenergic receptor autoantibody	52
Gemcitabine elaidate and ONC201 combination therapy for inhibiting pancreatic cancer in a KRAS mutated syngeneic mouse model	52
From mechanisms to markers: role of pyroptosis in revolutionizing thyroid cancer care	52
Heat shock protein 90α reduces CD8+ T cell exhaustion in acute lung injury induced by lipopolysaccharide	51
Immunotherapy for autoimmune encephalitis	50
IL-8 activates fibroblasts to promote the invasion of HNSCC cells via STAT3-MMP1	50
Repurposing proteasome inhibitors for improved treatment of triple-negative breast cancer	50
Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies	50
Methylation in cornea and corneal diseases: a systematic review	49
Exosomal miR-122-5p from tubular cells ameliorates renal interstitial fibrosis by regulating fibroblasts via HIF-1α	49
Fexofenadine protects against osteoarthritis by targeting Smad2 and STAT1 to enhance anabolism and binding cPLA2 to inhibit catabolism	48
Enhancer reprogramming: critical roles in cancer and promising therapeutic strategies	48
APOE4 promotes nigral tau hyperphosphorylation through cholesterol in atherosclerosis	48
Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway	47
LncRNA in tumorigenesis of non-small-cell lung cancer: From bench to bedside	47
YAP is required for prostate development, regeneration, and prostate stem cell function	47
MiR-134-5p inhibits the malignant phenotypes of osteosarcoma via ITGB1/MMP2/PI3K/Akt pathway	46
Comprehensive analysis of cellular metrics: From proliferation to mitochondrial membrane potential and cell death in a single sample	45
Loss of Ripk3 attenuated neutrophil accumulation in a lipopolysaccharide-induced zebrafish inflammatory model	45
Metabolic reprogramming in melanoma therapy	45
LncRNA XIST accelerates burn wound healing by promoting M2 macrophage polarization through targeting IL-33 via miR-19b	45
Long non-coding RNA MAFG-AS1 promotes proliferation and metastasis of breast cancer by modulating STC2 pathway	45
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4	45
Circadian rhythm regulates the function of immune cells and participates in the development of tumors	45
Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress	44
Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer	44
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner	43
Rapid iPSC-derived neuromuscular junction model uncovers motor neuron dominance in amyotrophic lateral sclerosis cytopathy	43
NEDD8-conjugating enzyme E2s: critical targets for cancer therapy	43
Nesprin-2 contains BH3-like motifs that can promote cell death	43
N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling	43
Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor	43
PGD2 displays distinct effects in diffuse large B-cell lymphoma depending on different concentrations	42
hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM2	42
SOX17-mediated MALAT1-miR-199a-HIF1α axis confers sensitivity in esophageal squamous cell carcinoma cells to radiotherapy	42
Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target	41
Increased efficacy of PARP inhibitors against cisplatin-sensitive and -resistant ovarian cancer cells mediated via ATR and ATM inhibition	41
Circular RNA hsa_circ_0001846 facilitates the malignant behaviors of pancreatic cancer by sponging miR-204-3p and upregulating KRAS expression	40
Correction: FTO promotes tumour proliferation in bladder cancer via the FTO/miR-576/CDK6 axis in an m6A-dependent manner	40
LEADR, a p63 target, dampens interferon signalling in bladder cancer	39
Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease	39
DSE inhibits melanoma progression by regulating tumor immune cell infiltration and VCAN	39
Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA	39
Tp53 haploinsufficiency is involved in hotspot mutations and cytoskeletal remodeling in gefitinib-induced drug-resistant EGFRL858R-lung cancer mice	39
Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response	39
Anti-CCL2 therapy reduces oxygen toxicity to the immature lung	39
MED15 is upregulated by HIF-2α and promotes proliferation and metastasis in clear cell renal cell carcinoma via activation of SREBP-dependent fatty acid synthesis	38
RASAL2 regulates the cell cycle and cyclin D1 expression through PI3K/AKT signalling in prostate tumorigenesis	38
Oleanolic acid combined with aspirin plays antitumor roles in colorectal cancer via the Akt/NFκB/IκBα/COX2 pathway	38
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750	38
Correction to: Microfluidic deep mutational scanning of the human executioner caspases reveals differences in structure and regulation	37
LncRNA LYPLAL1-DT screening from type 2 diabetes with macrovascular complication contributes protective effects on human umbilical vein endothelial cells via regulating the miR-204-5p/SIRT1 axis	37
Metal-polyphenol-network coated R612F nanoparticles reduce drug resistance in hepatocellular carcinoma by inhibiting stress granules	37
Correction: Tim-3 protects against cisplatin nephrotoxicity by inhibiting NF-κB-mediated inflammation	37
Fatty acid amide hydrolase drives adult mammary gland development by promoting luminal cell differentiation	37
LIGHT deficiency attenuates acute kidney disease development in an in vivo experimental renal ischemia and reperfusion injury model	37
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A	37
Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis	37
Deletion in RMST lncRNA impairs hypothalamic neuronal development in a human stem cell-based model of Kallmann Syndrome	37
CAPG is a novel biomarker for early gastric cancer and is involved in the Wnt/β-catenin signaling pathway	37
An evolutionarily conserved role for separase in the regulation of nuclear lamins	36
Developing novel Lin28 inhibitors by computer aided drug design	36
ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer	36
FGFR inhibition as a new therapeutic strategy to sensitize glioblastoma stem cells to tumor treating fields	36
Gastrointestinal acute radiation syndrome: current knowledge and perspectives	36
IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure	36
RETRACTED ARTICLE: MIR600HG sponges miR-125a-5p to regulate glycometabolism and cisplatin resistance of oral squamous cell carcinoma cells via mediating RNF44	36
The potential role of hydrogen sulfide in cancer cell apoptosis	36
PARP4 deficiency enhances sensitivity to ATM inhibitor by impairing DNA damage repair in melanoma	35
Different types of cell death and their shift in shaping disease	35
CREB5 promotes nodal metastasis of cervical cancer by regulation of APLN-induced lymphangiogenesis	35
Mechanisms of ferroptosis and targeted therapeutic approaches in urological malignancies	35
Author Correction: Gelatine nanostructured lipid carrier encapsulated FGF15 inhibits autophagy and improves recovery in spinal cord injury	35
BAP1 inactivation promotes lactate production by leveraging the subcellular localization of LDHA in melanoma	35
Overcoming apoptotic resistance afforded by Bcl-2 in lymphoid tumor cells: a critical role for dexamethasone	35
Standardized assays to monitor drug sensitivity in hematologic cancers	35
CRISPR/Cas9 screening identifies SUV39H2 as a key regulator of oHSV-1 resistance in oral squamous cell carcinoma	35
Mechanical stiffness promotes skin fibrosis through Piezo1-mediated arginine and proline metabolism	35

UCK2 promotes intrahepatic cholangiocarcinoma progression and desensitizes cisplatin treatment by PI3K/AKT/mTOR/autophagic axis	35
Organoids and organs-on-chips: insights into predicting the efficacy of systemic treatment in colorectal cancer	35
Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway	34
Decoding MUC1 and AR axis in a radiation-induced neuroendocrine prostate cancer cell-subpopulation unveils novel therapeutic targets	34
Role of Sox9 in BPD and its effects on the Wnt/β-catenin pathway and AEC-II differentiation	33
The LTB4-BLT1 axis attenuates influenza-induced lung inflammation by suppressing NLRP3 activation	33
Maternal linoleic acid-rich diet ameliorates bilirubin neurotoxicity in offspring mice	33
USP18 deubiquitinates and stabilizes SOX9 to promote the stemness and malignant progression of glioblastoma	33
Antisense lncRNA NNT-AS1 promoted esophageal squamous cell carcinoma progression by regulating its sense gene NNT expression	33
Tissue-resident Klebsiella quasipneumoniae contributes to progression of idiopathic pulmonary fibrosis by triggering macrophages mitophagy in mice	33
De-escalation antibiotic therapy alleviates organ injury through modulation of NETs formation during sepsis	33
Myeloid PTEN loss affects the therapeutic response by promoting stress granule assembly and impairing phagocytosis by macrophages in breast cancer	33
Nucleophosmin 1 cooperates with BRD4 to facilitate c-Myc transcription to promote prostate cancer progression	33
Inhibition of acetyl-CoA carboxylase impaired tubulin palmitoylation and induced spindle abnormalities	33
NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma	33
ERBB3 influences the ferroptosis pathway via modulation of lipid peroxidation and GSH synthesis in gastric cancer	32
Downregulation of KLF10 contributes to the regeneration of survived renal tubular cells in cisplatin-induced acute kidney injury via ZBTB7A-KLF10-PTEN axis	32
Correction: Heparanase promotes endothelial-to-mesenchymal transition in diabetic glomerular endothelial cells through mediating ERK signaling	32
Uveitic glaucoma-like features in Yap conditional knockout mice	32
Integrated stress response is involved in the 24(S)-hydroxycholesterol-induced unconventional cell death mechanism	32
Circular RNAs and mammalian follicular development: current insights and future prospects—an updated review	31
AMPK-induced novel phosphorylation of RUNX1 inhibits STAT3 activation and overcome imatinib resistance in chronic myelogenous leukemia (CML) subjects	31
N6-methyladenosine (m6A) writer METTL5 represses the ferroptosis and antitumor immunity of gastric cancer	31
Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2	31
Hsa_circ_0007967 promotes gastric cancer proliferation through the miR-411-5p/MAML3 axis	31
High-dose-androgen-induced autophagic cell death to suppress the Enzalutamide-resistant prostate cancer growth via altering the circRNA-BCL2/miRNA-198/AMBRA1 signaling	31
Organoid modeling meets cancers of female reproductive tract	31
Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer	31
Aging aggravated liver ischemia and reperfusion injury by promoting oxidized mtDNA mediated-macrophage pyroptosis through acetylated MCU-dependent calcium uptake	31
Saikosaponin‑D triggers cancer cell death by targeting the PIM1/c-Myc axis to reprogram oncogenic alternative splicing	31
Serum amyloid protein A in inflammatory bowel disease: from bench to bedside	31
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway	31
Long noncoding RNA profiling unveils LINC00960 as unfavorable prognostic biomarker promoting triple negative breast cancer progression	31
Targeting the redox-programmed cell death axis in breast cancer: from molecular mechanisms to therapeutic resistance	31
RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription	31
Exploiting dysregulated iron homeostasis to eradicate persistent high-grade serous ovarian cancer	30
circ_0004140 promotes LUAD tumor progression and immune resistance through circ_0004140/miR-1184/CCL22 axis	30
Lysophosphatidic acid exerts protective effects on HEI-OC1 cells against cytotoxicity of cisplatin by decreasing apoptosis, excessive autophagy, and accumulation of ROS	30
UBAP2L promotes gastric cancer metastasis by activating NF-κB through PI3K/AKT pathway	30
The miRNA and PD-1/PD-L1 signaling axis: an arsenal of immunotherapeutic targets against lung cancer	30
CaMKIV mediates spine growth deficiency of hippocampal neurons by regulation of EGR3/BDNF signal axis in congenital hypothyroidism	30
TAZ promotes osteogenic differentiation of mesenchymal stem cells line C3H10T1/2, murine multi-lineage cells lines C2C12, and MEFs induced by BMP9	30
Tumor-derived extracellular vesicles inhibit HGF/c-Met and EGF/EGFR pathways to accelerate the radiosensitivity of nasopharyngeal carcinoma cells via microRNA-142-5p delivery	29
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis	29
Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4	29
A bibliometric analysis of ferroptosis, necroptosis, pyroptosis, and cuproptosis in cancer from 2012 to 2022	29
Synergistic mechanism between the endoplasmic reticulum and mitochondria and their crosstalk with other organelles	29
Oncogenic microRNA-181d binding to OGT contributes to resistance of ovarian cancer cells to cisplatin	29
Interplay between genes and social environment: from epigenetics to precision medicine	29
Mesenchymal stem cell-derived extracellular vesicles transfer miR-598 to inhibit the growth and metastasis of non-small-cell lung cancer by targeting THBS2	29
MiR-146a-5p deficiency in extracellular vesicles of glioma-associated macrophages promotes epithelial-mesenchymal transition through the NF-κB signaling pathway	29
The cancer/testis antigen HORMAD1 mediates epithelial–mesenchymal transition to promote tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway in lung cancer	29
Hypoxia-induced epigenetic regulation of miR-485-3p promotes stemness and chemoresistance in pancreatic ductal adenocarcinoma via SLC7A11-mediated ferroptosis	29
4-aminopyridine attenuates inflammation and apoptosis and increases angiogenesis to promote skin regeneration following a burn injury in mice	29
PLK1 inhibition promotes apoptosis and DNA damage in glioma stem cells by regulating the nuclear translocation of YBX1	29
SOX2 and OCT4 mediate radiation and drug resistance in pancreatic tumor organoids	29
TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination	29
A comprehensive review of human trophoblast fusion models: recent developments and challenges	28
NAT10-mediated upregulation of GAS5 facilitates immune cell infiltration in non-small cell lung cancer via the MYBBP1A-p53/IRF1/type I interferon signaling axis	28
Diabetes impairs fracture healing through Foxo1 mediated disruption of ciliogenesis	28
Human myeloid differentiation by BMP4 signaling through the VDR pathway in acute myeloid leukemia	28
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis	28
Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species	28
The trigger for pancreatic disease: NLRP3 inflammasome	28
Insights on the crosstalk among different cell death mechanisms	28
Disulfidptosis in tumor progression	28
NOXA exacerbates endoplasmic-reticulum-stress-induced intervertebral disc degeneration by activating apoptosis and ECM degradation	28
METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism	28
Ferroptosis: Emerging mechanisms, biological function, and therapeutic potential in cancer and inflammation	28
Carfilzomib relieves pancreatitis-initiated pancreatic ductal adenocarcinoma by inhibiting high-temperature requirement protein A1	28
A miR-34a-guided, tRNAiMet-derived, piR_019752-like fragment (tRiMetF31) suppresses migration and angiogenesis of breast cancer cells via targeting PFKFB3	28
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis	27
Targeting ANXA7/LAMP5-mTOR axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy in mice	27
Targeting IL8 as a sequential therapy strategy to overcome chemotherapy resistance in advanced gastric cancer	27
Pre-clinical safety and therapeutic efficacy of a plant-based alkaloid in a human colon cancer xenograft model	27
Perilipin2-dependent lipid droplets accumulation promotes metastasis of oral squamous cell carcinoma via epithelial-mesenchymal transition	27
High Tau expression correlates with reduced invasion and prolonged survival in Ewing sarcoma	27
DDX3 is critical for female fertility via translational control in oogenesis	27
Regulation of Hippo/YAP axis in colon cancer progression by the deubiquitinase JOSD1	27
Cuproptosis and cuproptosis-related cell death and genes: mechanistic links to spermatogenic cell death	27
PINK1 ameliorates acute-on-chronic liver failure by inhibiting apoptosis through mTORC2/AKT signaling	27
A testis-specific lncRNA functions as a post-transcriptional regulator of MDM2 and stimulates apoptosis of testicular germ cell tumor cells	27
Primary cilia suppress Ripk3-mediated necroptosis	27
The nociceptin receptor promotes autophagy through NF-kB signaling and is transcriptionally regulated by E2F1 in HCC	27
Reformed islets: a long-term primary cell platform for exploring mouse and human islet biology	27
NCOA7 inhibits renal cancer progression by inducing autophagy and lipid metabolism through V-ATPase interaction	26
Novel prognostic marker LINC00205 promotes tumorigenesis and metastasis by competitively suppressing miRNA-26a in gastric cancer	26
PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling	26
METTL3-mediated deficiency of lncRNA HAR1A drives non-small cell lung cancer growth and metastasis by promoting ANXA2 stabilization	26
KDM4C silencing inhibits cell migration and enhances radiosensitivity by inducing CXCL2 transcription in hepatocellular carcinoma	26
Gas6 in chronic liver disease—a novel blood-based biomarker for liver fibrosis	26
Dysregulation of SNX1-retromer axis in pharmacogenetic models of Parkinson’s disease	26
Repositioning Lomitapide to block ZDHHC5-dependant palmitoylation on SSTR5 leads to anti-proliferation effect in preclinical pancreatic cancer models	26
Targeting matrix metallopeptidase 2 by hydroxyurea selectively kills acute myeloid mixed-lineage leukemia	26
Unveiling the nexus between environmental exposures and testicular damages: revelations from autophagy and oxidative stress imbalance	26