Cell Death Discovery

Article	Citations
Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model	588
MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway	303
AXL tyrosine kinase inhibitor TP-0903 induces ROS trigger neuroblastoma cell apoptosis via targeting the miR-335-3p/DKK1 expression	268
Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion	258
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death	248
N6-methyladenosine: a key regulator in ocular disease mechanisms and treatment	241
Matrix metalloproteinase-10 promotes kidney fibrosis by transactivating β-catenin signaling	186
USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression	185
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics	171
Retraction Note to: Inhibition of TGF-β repairs spinal cord injury by attenuating EphrinB2 expressing through inducing miR-484 from fibroblast	164
Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis	154
GILT stabilizes cofilin to promote the metastasis of prostate cancer	154
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1	151
LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma	150
MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1	147
IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL10	142
Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc42	138
Replication stress primes a trophectoderm fate in embryonic stem cells	137
Radiobiological characterisation of a 28 MeV proton beam delivered by the MC-40 cyclotron	135
An electrophysiological and proteomics roadmap for human induced glutamatergic neurons: fine-tuning of culture conditions for pathophysiological studies	127
ATP binding to lysozyme and superfolder GFP amyloid fibrils induces aggregate remodeling and attenuates their cytotoxicity	126
Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis	123
FKBP5 isoforms shape immune pathways related to tumor tolerance	120
Therapeutic targeting of STING-IL6/STAT3 axis to inhibit osteoclastic niche formation and breast cancer bone metastasis	116
Targeting the ODC1-YBX1 axis reverses gastric cancer chemoresistance via transcriptional control of SLC7A11-mediated ferroptosis	115

ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues	115
Dysregulated nuclear Lamin B1 in DYT1 dystonia thickens nuclear lamina and disrupts 14-3-3 proteins	115
Glucocorticoid-induced Leucine Zipper (GILZ) is a novel secreted protein by intestinal L-cells and is dysregulated during active ulcerative colitis	114
Hippo pathway and NLRP3-driven NETosis in macrophages: Mechanisms of viral pneumoniaaggravation	112
RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation	110
AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury	109
LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism	107
The role of ankyrin repeat-containing proteins in epigenetic and transcriptional regulation	105
N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction	105
FOXM1 inhibition primes terminal differentiation of human iPSC-derived hepatocytes	104
Exosomal circRNAs: key modulators in breast cancer progression	104
Dual control of liver regeneration by Nr1d1 homeostasis and Klf2 checkpoint	103
Smoking-induced microbial dysbiosis: a key driver of systemic diseases and emerging therapeutic opportunities	102
Oncometabolite signatures from tumor-stroma crosstalk as potential non-invasive biomarkers	101
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH	99
Epitranscriptomic control of cancer: the emerging roles of m⁵C and ac⁴C RNA modifications	98
CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma	93
Exploring necroptosis: mechanistic analysis and antitumor potential of nanomaterials	92
Vascular smooth muscle cell metabolic reprogramming and phenotypic remodeling in atherosclerosis	89
Stem cell-derived intestinal organoids: a novel modality for IBD	88
The plasticity of epithelial cells and its potential in the induced differentiation of gastric cancer	87
Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis	87
Cellular senescence of renal tubular epithelial cells in acute kidney injury	87
Long non-coding RNA-encoded micropeptides: functions, mechanisms and implications	87
Absence of Rnf126 causes male infertility with multiple morphological abnormalities of the sperm flagella	87
New insights into constitutive neutrophil death	86
STING agonists trigger monocyte death via apoptosis, pyroptosis, caspase-8 activation and mitochondrial dysfunction	85
Diverse functions of NLRP3 inflammasome in PANoptosis and diseases	84
Lipids associated with autophagy: mechanisms and therapeutic targets	83
Targeting mitochondrial autophagy for anti-aging	81
USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target	81
POLE2 promotes osteosarcoma progression by enhancing the stability of CD44	81
Metformin protects retinal ganglion cells in a preclinical model of retinal ischemia/reperfusion injury and stabilizes visual field in diabetic patients with glaucoma	81
Tissue microenvironment induces tissue specificity of ILC2	79
Mitochondrial metabolic reprogramming in colorectal cancer: mechanisms of resistance and future clinical interventions	79
Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma	78
In vitro cytotoxic mechanisms of Pt(O,O′-acac)(γ-acac)(DMS): mitochondrial dysfunction and impaired autophagy in U251 cell line	77
Inhibition of TGF-beta signaling protects from alpha-synuclein induced toxicity	77
Differential effects of HDAC inhibitors in the RhoI255d mouse model for autosomal dominant retinitis pigmentosa	77
MiR-134-5p inhibits the malignant phenotypes of osteosarcoma via ITGB1/MMP2/PI3K/Akt pathway	77
Dynamic changes of the immune microenvironment in ovarian cancer following neoadjuvant chemotherapy	76
Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress	76
CREB suppresses PGRP-SC2 to drive age-related immune senescence and gut dysbiosis in Drosophila	75
Neddylation inhibition induces DNA double-strand breaks, hampering tumor growth in vivo, and promotes radiosensitivity in PAX3–FOXO1 rhabdomyosarcoma	74
NRF2 transcriptionally regulates Caspase-11 expression to activate HMGB1 release by Autophagy-deficient hepatocytes	73
Correction: Let-7b-5p inhibits breast cancer cell growth and metastasis via repression of hexokinase 2-mediated aerobic glycolysis	73
Modulation of stress granules by lobeline increases cell death in hypoxia and impacts the ability of glioblastoma cells to secrete extracellular vesicles	71
APOE4 promotes nigral tau hyperphosphorylation through cholesterol in atherosclerosis	70
From mechanisms to markers: role of pyroptosis in revolutionizing thyroid cancer care	70
YAP is required for prostate development, regeneration, and prostate stem cell function	69

Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway	68
Inhibition of RIPK1/RIPK3-MLKL inflammatory signaling pathway activation attenuates preterm birth	68
Correction: Autophagy in hepatic ischemia–reperfusion injury	68
Methylation in cornea and corneal diseases: a systematic review	66
The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma	66
Disruption of thrombospondin 1/2-integrin β1 axis impairs cell adhesion and tumor growth in intrahepatic cholangiocarcinoma	66
Fexofenadine protects against osteoarthritis by targeting Smad2 and STAT1 to enhance anabolism and binding cPLA2 to inhibit catabolism	66
Dynamic calcium–potassium balancing by KCNMA1 preserves the epithelial/mesenchymal hybrid state and modulates therapy response in ovarian cancer	66
Repurposing proteasome inhibitors for improved treatment of triple-negative breast cancer	65
LncRNA in tumorigenesis of non-small-cell lung cancer: From bench to bedside	65
COVID-19 related neurological manifestations in Parkinson’s disease: has ferroptosis been a suspect?	65
MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling	64
TRA2A negatively regulates HIV-1-induced macrophage pyroptosis by mediating TXNIP expression in an m6A-dependent manner	64
Polyploidy mitigates the impact of DNA damage while simultaneously bearing its burden	64
Heat shock protein 90α reduces CD8+ T cell exhaustion in acute lung injury induced by lipopolysaccharide	63
Exosomal miR-122-5p from tubular cells ameliorates renal interstitial fibrosis by regulating fibroblasts via HIF-1α	63
Placenta models for HIV-1-ART-nicotine comorbidity research: advances and remaining challenges	62
Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies	62
IL-8 activates fibroblasts to promote the invasion of HNSCC cells via STAT3-MMP1	62
Comprehensive analysis of cellular metrics: From proliferation to mitochondrial membrane potential and cell death in a single sample	61
Fosinopril mediates antitumor efficacy by inducing GSDME-dependent pyroptosis in NSCLC	61
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4	60
BRD7 suppresses tumor chemosensitivity to CHK1 inhibitors by inhibiting USP1-mediated deubiquitination of CHK1	60
Immunotherapy for autoimmune encephalitis	60
Gemcitabine elaidate and ONC201 combination therapy for inhibiting pancreatic cancer in a KRAS mutated syngeneic mouse model	60
Exploring the metabolic signaling network of GFPT in cancer	59
LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins	59
Circadian rhythm regulates the function of immune cells and participates in the development of tumors	58
NAT10 promotes cisplatin resistance and immune escape by increasing the expression of DUSP1 and PD-L1 in gastric cancer	58
Hexamethylene amiloride induces lysosome-mediated cell death in multiple myeloma through transcription factor E3	58
VDR and deubiquitination control neuronal oxidative stress and microglial inflammation in Parkinson’s disease	58
The EZH2-H3K27me3 axis modulates aberrant transcription and apoptosis in cyclophosphamide-induced ovarian granulosa cell injury	58
BET inhibition unmasks a targetable glycolytic dependency through a HIF1α stabilization and driven transcriptional program in a defined subset of triple-negative breast Cancer	58
Metabolic reprogramming in melanoma therapy	57
TRPS1 regulates the opposite effect of progesterone via RANKL in endometrial carcinoma and breast carcinoma	57
Enhancer reprogramming: critical roles in cancer and promising therapeutic strategies	56
Epirubicin induces cardiotoxicity through disrupting ATP6V0A2-dependent lysosomal acidification and triggering ferroptosis in cardiomyocytes	56
Thapsigargin triggers a non-apoptotic, caspase-independent programmed cell death in basophilic leukaemia cells	56
Rapid iPSC-derived neuromuscular junction model uncovers motor neuron dominance in amyotrophic lateral sclerosis cytopathy	55
Targeting Txnip-mediated metabolic reprogramming has therapeutic potential for osteoarthritis	55
Nesprin-2 contains BH3-like motifs that can promote cell death	55
Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor	55
Thioredoxin system dysregulation and calpain activation drive myocardial disulfidptosis via pathological disulfide bonds remodeling	54
Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis	54
A positive feedback loop between TKT and c-Myc drives TACE resistance in hepatocellular carcinoma	53
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A	53
Tp53 haploinsufficiency is involved in hotspot mutations and cytoskeletal remodeling in gefitinib-induced drug-resistant EGFRL858R-lung cancer mice	53
Oleanolic acid combined with aspirin plays antitumor roles in colorectal cancer via the Akt/NFκB/IκBα/COX2 pathway	53
MEKK3 bridges gut-brain communication and cerebral cavernous malformation pathogenesis	53
Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response	52
Metal-polyphenol-network coated R612F nanoparticles reduce drug resistance in hepatocellular carcinoma by inhibiting stress granules	52
An evolutionarily conserved role for separase in the regulation of nuclear lamins	52
Increased efficacy of PARP inhibitors against cisplatin-sensitive and -resistant ovarian cancer cells mediated via ATR and ATM inhibition	52
PGD2 displays distinct effects in diffuse large B-cell lymphoma depending on different concentrations	52
Developing novel Lin28 inhibitors by computer aided drug design	51
Correction: Tim-3 protects against cisplatin nephrotoxicity by inhibiting NF-κB-mediated inflammation	51
Circular RNA hsa_circ_0001846 facilitates the malignant behaviors of pancreatic cancer by sponging miR-204-3p and upregulating KRAS expression	50
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750	50
GSDMD deficiency attenuates BPD by suppressing macrophage pyroptosis and promoting M2 polarization	50
LEADR, a p63 target, dampens interferon signalling in bladder cancer	50
Fatty acid amide hydrolase drives adult mammary gland development by promoting luminal cell differentiation	50
Overcoming apoptotic resistance afforded by Bcl-2 in lymphoid tumor cells: a critical role for dexamethasone	49
Rafoxanide disrupts mitochondrial homeostasis through VDAC1 modulation in colorectal cancer cells	49
N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling	49
Targeting cell death in Crohn’s disease: from mechanisms to medicines	48
NAT10 promotes gallbladder cancer progression by remodeling cholesterol metabolism via PCSK9 mRNA acetylation	48
Misregulated alternative splicing in endometriosis: a role for aberrant mRNA variants in endometriotic cell growth	48
Nicotinamide N-methyltransferase as a therapeutic target in taxane-resistant castration-resistant prostate cancer	48
LIGHT deficiency attenuates acute kidney disease development in an in vivo experimental renal ischemia and reperfusion injury model	48
High-throughput strategy for targeting MDM2 in uveal melanoma to reverse radiation therapy resistance	47
HAAO‑derived quinolinic acid fuels FDPS‑dependent AR signaling and sensitizes prostate cancer to combination therapy	47
Multidimensional regulatory roles and therapeutic applications of SRSF7 in cancer	47
Fibroblast adipogenesis restricts hemangioma growth through a PPARγ/Hippo-YAP/TAZ axis that promotes endothelial apoptosis and cell cycle arrest	47
hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM2	47
PPA1 promotes oxidative phosphorylation and malignant progression of colorectal cancer under glucose restriction via AMPK/ULK1/FUNDC1-mediated mitophagy	46
Mechanisms of ferroptosis and targeted therapeutic approaches in urological malignancies	46
FGFR inhibition as a new therapeutic strategy to sensitize glioblastoma stem cells to tumor treating fields	46
GPR84 aggravates lung inflammation through activating ZBP1-PANoptosome mediated PANoptosis following IAV infection	46
Organoids and organs-on-chips: insights into predicting the efficacy of systemic treatment in colorectal cancer	46
Gastrointestinal acute radiation syndrome: current knowledge and perspectives	46

MED15 is upregulated by HIF-2α and promotes proliferation and metastasis in clear cell renal cell carcinoma via activation of SREBP-dependent fatty acid synthesis	45
CAPG is a novel biomarker for early gastric cancer and is involved in the Wnt/β-catenin signaling pathway	45
BAP1 inactivation promotes lactate production by leveraging the subcellular localization of LDHA in melanoma	45
DSE inhibits melanoma progression by regulating tumor immune cell infiltration and VCAN	44
CREB5 promotes nodal metastasis of cervical cancer by regulation of APLN-induced lymphangiogenesis	44
The potential role of hydrogen sulfide in cancer cell apoptosis	44
IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure	44
NEDD8-conjugating enzyme E2s: critical targets for cancer therapy	44
Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease	43
Mechanical stiffness promotes skin fibrosis through Piezo1-mediated arginine and proline metabolism	43
Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA	42
UCK2 promotes intrahepatic cholangiocarcinoma progression and desensitizes cisplatin treatment by PI3K/AKT/mTOR/autophagic axis	42
ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer	42
Anti-CCL2 therapy reduces oxygen toxicity to the immature lung	41
Deletion in RMST lncRNA impairs hypothalamic neuronal development in a human stem cell-based model of Kallmann Syndrome	41
Different types of cell death and their shift in shaping disease	41
Mitophagy-dependent mitochondrial DNA release links ionizing radiation to immunogenic cell death in pancreatic cancer	41
Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target	41
Uveitic glaucoma-like features in Yap conditional knockout mice	41
The LTB4-BLT1 axis attenuates influenza-induced lung inflammation by suppressing NLRP3 activation	41
Standardized assays to monitor drug sensitivity in hematologic cancers	41
Maternal linoleic acid-rich diet ameliorates bilirubin neurotoxicity in offspring mice	41
Saikosaponin‑D triggers cancer cell death by targeting the PIM1/c-Myc axis to reprogram oncogenic alternative splicing	40
Hypoxia promotes progression of cervical cancer by modulating the ATXN3-enhanced P53 stability or STAT5 phosphorylation	40
PARP4 deficiency enhances sensitivity to ATM inhibitor by impairing DNA damage repair in melanoma	40
hnRNP A1 inhibits colorectal cancer tumorigenesis and progression by regulating fatty acid metabolism and RNA stability	40
MiR-146a-5p deficiency in extracellular vesicles of glioma-associated macrophages promotes epithelial-mesenchymal transition through the NF-κB signaling pathway	40
Integrated stress response is involved in the 24(S)-hydroxycholesterol-induced unconventional cell death mechanism	40
Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2	39
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis	39
Exploiting dysregulated iron homeostasis to eradicate persistent high-grade serous ovarian cancer	39
NOXA exacerbates endoplasmic-reticulum-stress-induced intervertebral disc degeneration by activating apoptosis and ECM degradation	39
Nucleophosmin 1 cooperates with BRD4 to facilitate c-Myc transcription to promote prostate cancer progression	39
Antisense lncRNA NNT-AS1 promoted esophageal squamous cell carcinoma progression by regulating its sense gene NNT expression	39
AMPK is dispensable for physiological podocyte and glomerular functions but prevents glomerular fibrosis in experimental diabetes	38
Circular RNAs and mammalian follicular development: current insights and future prospects—an updated review	38
Decoding MUC1 and AR axis in a radiation-induced neuroendocrine prostate cancer cell-subpopulation unveils novel therapeutic targets	38
CaMKIV mediates spine growth deficiency of hippocampal neurons by regulation of EGR3/BDNF signal axis in congenital hypothyroidism	38
Mesenchymal stem cell-derived extracellular vesicles transfer miR-598 to inhibit the growth and metastasis of non-small-cell lung cancer by targeting THBS2	38
A bibliometric analysis of ferroptosis, necroptosis, pyroptosis, and cuproptosis in cancer from 2012 to 2022	38
NRG1/PDGFC loop between fibroblasts and cancer cells drives paclitaxel resistance via ferroptosis suppression in breast cancer	38
AMPK-induced novel phosphorylation of RUNX1 inhibits STAT3 activation and overcome imatinib resistance in chronic myelogenous leukemia (CML) subjects	38
TAZ promotes osteogenic differentiation of mesenchymal stem cells line C3H10T1/2, murine multi-lineage cells lines C2C12, and MEFs induced by BMP9	38
CRISPR/Cas9 screening identifies SUV39H2 as a key regulator of oHSV-1 resistance in oral squamous cell carcinoma	38
Tissue-resident Klebsiella quasipneumoniae contributes to progression of idiopathic pulmonary fibrosis by triggering macrophages mitophagy in mice	38
TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination	37
N6-methyladenosine (m6A) writer METTL5 represses the ferroptosis and antitumor immunity of gastric cancer	37
Inhibition of acetyl-CoA carboxylase impaired tubulin palmitoylation and induced spindle abnormalities	37
Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4	37
Downregulation of KLF10 contributes to the regeneration of survived renal tubular cells in cisplatin-induced acute kidney injury via ZBTB7A-KLF10-PTEN axis	37
Myeloid PTEN loss affects the therapeutic response by promoting stress granule assembly and impairing phagocytosis by macrophages in breast cancer	37
Endothelial mechanosensitive transcription factor BHLHE40 induced by Piezo1 suppresses endothelial ferroptosis and inflammation via SLC7A11	37
Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer	37
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway	37
Serum amyloid protein A in inflammatory bowel disease: from bench to bedside	36
Organoid modeling meets cancers of female reproductive tract	36
USP18 deubiquitinates and stabilizes SOX9 to promote the stemness and malignant progression of glioblastoma	36
Synergistic mechanism between the endoplasmic reticulum and mitochondria and their crosstalk with other organelles	36
Correction: NLRP3-mediated pyroptosis aggravates pressure overload-induced cardiac hypertrophy, fibrosis, and dysfunction in mice: cardioprotective role of irisin	36
Diabetes impairs fracture healing through Foxo1 mediated disruption of ciliogenesis	36
CERS6 promotes esophageal squamous cell carcinoma proliferation by increasing the stability of RPN1	36
NAT10-mediated upregulation of GAS5 facilitates immune cell infiltration in non-small cell lung cancer via the MYBBP1A-p53/IRF1/type I interferon signaling axis	36
PLK1 inhibition promotes apoptosis and DNA damage in glioma stem cells by regulating the nuclear translocation of YBX1	36
Role of Sox9 in BPD and its effects on the Wnt/β-catenin pathway and AEC-II differentiation	35
SOX2 and OCT4 mediate radiation and drug resistance in pancreatic tumor organoids	35
ERBB3 influences the ferroptosis pathway via modulation of lipid peroxidation and GSH synthesis in gastric cancer	34
Insights on the crosstalk among different cell death mechanisms	34
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis	34
RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription	34
Aging aggravated liver ischemia and reperfusion injury by promoting oxidized mtDNA mediated-macrophage pyroptosis through acetylated MCU-dependent calcium uptake	34
Targeting the redox-programmed cell death axis in breast cancer: from molecular mechanisms to therapeutic resistance	34
Interplay between genes and social environment: from epigenetics to precision medicine	34
Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species	34
Lysophosphatidic acid exerts protective effects on HEI-OC1 cells against cytotoxicity of cisplatin by decreasing apoptosis, excessive autophagy, and accumulation of ROS	34
The trigger for pancreatic disease: NLRP3 inflammasome	34
Effects of astrocytic PKM2 gene deletion on neuronal death following traumatic brain injury	33
Novel mechanism of neuronal hypoxia response: HIF-1α/STOML2 mediated PINK1-dependent mitophagy activation against neuronal injury	33
Long noncoding RNA profiling unveils LINC00960 as unfavorable prognostic biomarker promoting triple negative breast cancer progression	33
A comprehensive review of human trophoblast fusion models: recent developments and challenges	33
Cold-induced hepatocyte-derived exosomes activate brown adipose thermogenesis via miR-293-5p-mediated transcriptional reprogramming	33
NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma	33
The miRNA and PD-1/PD-L1 signaling axis: an arsenal of immunotherapeutic targets against lung cancer	33
Ferroptosis: Emerging mechanisms, biological function, and therapeutic potential in cancer and inflammation	33
A testis-specific lncRNA functions as a post-transcriptional regulator of MDM2 and stimulates apoptosis of testicular germ cell tumor cells	33
4-aminopyridine attenuates inflammation and apoptosis and increases angiogenesis to promote skin regeneration following a burn injury in mice	33
Hypoxia-induced epigenetic regulation of miR-485-3p promotes stemness and chemoresistance in pancreatic ductal adenocarcinoma via SLC7A11-mediated ferroptosis	33
Bacterial protein-oleate complexes induce ferroptosis-like cell death in colorectal cancer cells by disrupting cell membranes and inhibiting the β-catenin-GPX4 axis	33
Dependence of human cell survival and proliferation on the CASP3 prodomain	32
Correction: Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space	32
KDM4C silencing inhibits cell migration and enhances radiosensitivity by inducing CXCL2 transcription in hepatocellular carcinoma	32
Carfilzomib relieves pancreatitis-initiated pancreatic ductal adenocarcinoma by inhibiting high-temperature requirement protein A1	32
Reformed islets: a long-term primary cell platform for exploring mouse and human islet biology	32
PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling	32
The monkeypox virus suppresses autophagy by modulating Rubicon expression	32
Deciphering the STAT3-PXN positive feedback loop in GBM, IDH-wildtype: transcriptional regulation and inhibition of YB-1 ubiquitination	32