OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death Discovery is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression	226
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1	195
Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis	180
Retraction Note to: Inhibition of TGF-β repairs spinal cord injury by attenuating EphrinB2 expressing through inducing miR-484 from fibroblast	160
N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction	157
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer	155
GILT stabilizes cofilin to promote the metastasis of prostate cancer	146
Tissue microenvironment induces tissue specificity of ILC2	145
Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion	141
New insights into constitutive neutrophil death	117
Senescence as a dictator of patient outcomes and therapeutic efficacies in human gastric cancer	109
Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc42	107
TM7SF2 regulates cell proliferation and apoptosis by activation of C-Raf/ERK pathway in cervical cancer	106
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death	104
Hippo pathway and NLRP3-driven NETosis in macrophages: Mechanisms of viral pneumoniaaggravation	102
AXL tyrosine kinase inhibitor TP-0903 induces ROS trigger neuroblastoma cell apoptosis via targeting the miR-335-3p/DKK1 expression	100
RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation	99
Diverse functions of NLRP3 inflammasome in PANoptosis and diseases	96
Radiobiological characterisation of a 28 MeV proton beam delivered by the MC-40 cyclotron	93
Lipids associated with autophagy: mechanisms and therapeutic targets	87
Mitochondrial metabolic reprogramming in colorectal cancer: mechanisms of resistance and future clinical interventions	85
LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism	85
USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target	84
The plasticity of epithelial cells and its potential in the induced differentiation of gastric cancer	82
Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma	80

IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL10	79
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI	79
DUB3/KLF4 combats tumor growth and chemoresistance in hepatocellular carcinoma	79
Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model	79
Cellular senescence of renal tubular epithelial cells in acute kidney injury	77
Stem cell-derived intestinal organoids: a novel modality for IBD	77
Exosomal circRNAs: key modulators in breast cancer progression	76
Long non-coding RNA-encoded micropeptides: functions, mechanisms and implications	76
ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues	75
Matrix metalloproteinase-10 promotes kidney fibrosis by transactivating β-catenin signaling	74
Roles and action mechanisms of WNT4 in cell differentiation and human diseases: a review	74
POLE2 promotes osteosarcoma progression by enhancing the stability of CD44	73
MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1	73
An mTOR and DNA-PK dual inhibitor CC-115 hinders non-small cell lung cancer cell growth	73
The role of ankyrin repeat-containing proteins in epigenetic and transcriptional regulation	72
LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma	71
Exploring necroptosis: mechanistic analysis and antitumor potential of nanomaterials	69
Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis	69
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics	64
PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway	64
Targeting NAD+: is it a common strategy to delay heart aging?	63
Absence of Rnf126 causes male infertility with multiple morphological abnormalities of the sperm flagella	63
AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury	63
Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis	63
CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma	63
Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis	62
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression	62
The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer	62
CD95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a CD95 ligand-independent manner	61
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH	61
The pathological role of damaged organelles in renal tubular epithelial cells in the progression of acute kidney injury	61
MYC inhibition reprograms tumor immune microenvironment by recruiting T lymphocytes and activating the CD40/CD40L system in osteosarcoma	59
Immunotherapy for autoimmune encephalitis	58
MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling	58