OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death Discovery is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
A novel defined pyroptosis-related gene signature for predicting the prognosis of ovarian cancer	270
The caspase-3/GSDME signal pathway as a switch between apoptosis and pyroptosis in cancer	263
Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases	212
SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes	169
Identification of the pyroptosis‑related prognostic gene signature and the associated regulation axis in lung adenocarcinoma	129
Circular RNA cIARS regulates ferroptosis in HCC cells through interacting with RNA binding protein ALKBH5	113
Ferroptosis in liver disease: new insights into disease mechanisms	106
Progress in understanding the role of lncRNA in programmed cell death	102
Mitochondrial dysfunction in fibrotic diseases	93
Role of interleukins in the pathogenesis of pulmonary fibrosis	90
ACE2 expression and sex disparity in COVID-19	90
Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury	87
The role of neutrophil death in chronic inflammation and cancer	87
Extracellular vesicles in cardiovascular diseases	79
Parthenolide promotes the repair of spinal cord injury by modulating M1/M2 polarization via the NF-κB and STAT 1/3 signaling pathway	79
Digestive symptoms of COVID-19 and expression of ACE2 in digestive tract organs	69
The Janus-like role of proline metabolism in cancer	64
Mitochondrial damage and activation of the cytosolic DNA sensor cGAS–STING pathway lead to cardiac pyroptosis and hypertrophy in diabetic cardiomyopathy mice	62
The role of ferroptosis in breast cancer patients: a comprehensive analysis	61
Identification of a prognostic ferroptosis-related lncRNA signature in the tumor microenvironment of lung adenocarcinoma	61
SARS-CoV-2 infection serology: a useful tool to overcome lockdown?	60
MFG-E8 accelerates wound healing in diabetes by regulating “NLRP3 inflammasome-neutrophil extracellular traps” axis	59
Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases	59
A comparative pharmaco-metabolomic study of glutaminase inhibitors in glioma stem-like cells confirms biological effectiveness but reveals differences in target-specificity	58
ROS induces NETosis by oxidizing DNA and initiating DNA repair	58

O-GlcNAcylation enhances sensitivity to RSL3-induced ferroptosis via the YAP/TFRC pathway in liver cancer	56
SIRT1 directly activates autophagy in human chondrocytes	56
Role of the nervous system in cancers: a review	56
How does mTOR sense glucose starvation? AMPK is the usual suspect	55
Inside the hypoxic tumour: reprogramming of the DDR and radioresistance	54
Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells	54
Recent progress in ferroptosis: inducers and inhibitors	53
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury	53
NLRP3-mediated pyroptosis aggravates pressure overload-induced cardiac hypertrophy, fibrosis, and dysfunction in mice: cardioprotective role of irisin	52
SARS-CoV-2 infection: can ferroptosis be a potential treatment target for multiple organ involvement?	52
Exosomes derived from miR-126-3p-overexpressing synovial fibroblasts suppress chondrocyte inflammation and cartilage degradation in a rat model of osteoarthritis	51
Liquid biopsies and cancer omics	51
The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer	50
Periodontitis-level butyrate-induced ferroptosis in periodontal ligament fibroblasts by activation of ferritinophagy	50
HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells	48
The METTL3/MALAT1/PTBP1/USP8/TAK1 axis promotes pyroptosis and M1 polarization of macrophages and contributes to liver fibrosis	47
Small size gold nanoparticles enhance apoptosis-induced by cold atmospheric plasma via depletion of intracellular GSH and modification of oxidative stress	47
The nuclear envelope: target and mediator of the apoptotic process	47
Human pluripotent stem cell-derived alveolar organoids for modeling pulmonary fibrosis and drug testing	46
Glucose metabolism involved in PD-L1-mediated immune escape in the malignant kidney tumour microenvironment	45
snoRNAs: functions and mechanisms in biological processes, and roles in tumor pathophysiology	45
Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis	45
Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy	45