OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death Discovery is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression	222
Inhibitor of DNA binding 2 (Id2) mediates microtubule polymerization in the brain by regulating αK40 acetylation of α-tubulin	184
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1	176
Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis	154
Retraction Note to: Inhibition of TGF-β repairs spinal cord injury by attenuating EphrinB2 expressing through inducing miR-484 from fibroblast	147
GILT stabilizes cofilin to promote the metastasis of prostate cancer	144
N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction	138
LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma	133
Exosomal circRNAs: key modulators in breast cancer progression	113
DUB3/KLF4 combats tumor growth and chemoresistance in hepatocellular carcinoma	107
PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway	106
Hippo pathway and NLRP3-driven NETosis in macrophages: Mechanisms of viral pneumoniaaggravation	105
Exploring necroptosis: mechanistic analysis and antitumor potential of nanomaterials	105
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics	102
The plasticity of epithelial cells and its potential in the induced differentiation of gastric cancer	97
Lipids associated with autophagy: mechanisms and therapeutic targets	96
Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis	95
The role of ankyrin repeat-containing proteins in epigenetic and transcriptional regulation	93
Absence of Rnf126 causes male infertility with multiple morphological abnormalities of the sperm flagella	91
Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis	87
Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model	83
Senescence as a dictator of patient outcomes and therapeutic efficacies in human gastric cancer	82
TM7SF2 regulates cell proliferation and apoptosis by activation of C-Raf/ERK pathway in cervical cancer	81
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death	78
Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc42	77

CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH	77
LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism	76
ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues	76
Radiobiological characterisation of a 28 MeV proton beam delivered by the MC-40 cyclotron	76
RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation	75
AXL tyrosine kinase inhibitor TP-0903 induces ROS trigger neuroblastoma cell apoptosis via targeting the miR-335-3p/DKK1 expression	74
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer	74
New insights into constitutive neutrophil death	72
The pathological role of damaged organelles in renal tubular epithelial cells in the progression of acute kidney injury	71
Tissue microenvironment induces tissue specificity of ILC2	71
Mitochondrial metabolic reprogramming in colorectal cancer: mechanisms of resistance and future clinical interventions	71
Diverse functions of NLRP3 inflammasome in PANoptosis and diseases	71
CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma	70
IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL10	68
Stem cell-derived intestinal organoids: a novel modality for IBD	68
POLE2 promotes osteosarcoma progression by enhancing the stability of CD44	68
The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer	68
Matrix metalloproteinase-10 promotes kidney fibrosis by transactivating β-catenin signaling	68
Roles and action mechanisms of WNT4 in cell differentiation and human diseases: a review	67
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression	65
Long non-coding RNA-encoded micropeptides: functions, mechanisms and implications	63
Targeting NAD+: is it a common strategy to delay heart aging?	62
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI	61
MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1	61
An mTOR and DNA-PK dual inhibitor CC-115 hinders non-small cell lung cancer cell growth	61
Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion	61
USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target	61
Cellular senescence of renal tubular epithelial cells in acute kidney injury	60
AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury	60
Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis	59
Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma	59
Long noncoding RNA SNHG1 silencing accelerates hepatocyte-like cell differentiation of bone marrow-derived mesenchymal stem cells to alleviate cirrhosis via the microRNA-15a/SMURF1/UVRAG axis	58
BRD7 suppresses tumor chemosensitivity to CHK1 inhibitors by inhibiting USP1-mediated deubiquitination of CHK1	58