OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death Discovery is 44. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases	311
A novel defined pyroptosis-related gene signature for predicting the prognosis of ovarian cancer	294
SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes	185
Identification of the pyroptosis‑related prognostic gene signature and the associated regulation axis in lung adenocarcinoma	142
Ferroptosis in liver disease: new insights into disease mechanisms	126
Progress in understanding the role of lncRNA in programmed cell death	115
Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury	114
Recent progress in ferroptosis: inducers and inhibitors	109
Role of interleukins in the pathogenesis of pulmonary fibrosis	108
Mitochondrial damage and activation of the cytosolic DNA sensor cGAS–STING pathway lead to cardiac pyroptosis and hypertrophy in diabetic cardiomyopathy mice	91
ROS induces NETosis by oxidizing DNA and initiating DNA repair	78
snoRNAs: functions and mechanisms in biological processes, and roles in tumor pathophysiology	74
Role of the nervous system in cancers: a review	70
The METTL3/MALAT1/PTBP1/USP8/TAK1 axis promotes pyroptosis and M1 polarization of macrophages and contributes to liver fibrosis	70
The role of ferroptosis in breast cancer patients: a comprehensive analysis	69
O-GlcNAcylation enhances sensitivity to RSL3-induced ferroptosis via the YAP/TFRC pathway in liver cancer	68
The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer	68
HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells	68
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury	66
Identification of a prognostic ferroptosis-related lncRNA signature in the tumor microenvironment of lung adenocarcinoma	66
GPX4-independent ferroptosis—a new strategy in disease’s therapy	64
Exosomes derived from miR-126-3p-overexpressing synovial fibroblasts suppress chondrocyte inflammation and cartilage degradation in a rat model of osteoarthritis	62
Mitochondrial event as an ultimate step in ferroptosis	61
NLRP3-mediated pyroptosis aggravates pressure overload-induced cardiac hypertrophy, fibrosis, and dysfunction in mice: cardioprotective role of irisin	59
Periodontitis-level butyrate-induced ferroptosis in periodontal ligament fibroblasts by activation of ferritinophagy	58

Liquid biopsies and cancer omics	56
SARS-CoV-2 infection: can ferroptosis be a potential treatment target for multiple organ involvement?	56
Regulating Nrf2-GPx4 axis by bicyclol can prevent ferroptosis in carbon tetrachloride-induced acute liver injury in mice	55
Implication of ferroptosis in aging	55
Glucose metabolism involved in PD-L1-mediated immune escape in the malignant kidney tumour microenvironment	54
Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model	54
M2 macrophage-derived extracellular vesicles facilitate CD8+T cell exhaustion in hepatocellular carcinoma via the miR-21-5p/YOD1/YAP/β-catenin pathway	54
Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis	53
Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy	53
Role of ferroptosis on tumor progression and immunotherapy	51
Carcinoma-associated fibroblasts derived exosomes modulate breast cancer cell stemness through exonic circHIF1A by miR-580-5p in hypoxic stress	48
Human pluripotent stem cell-derived alveolar organoids for modeling pulmonary fibrosis and drug testing	48
Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer	48
m6A-induced LINC00958 promotes breast cancer tumorigenesis via the miR-378a-3p/YY1 axis	47
Emerging roles of ferroptosis in cardiovascular diseases	47
Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis	47
Long COVID: an estrogen-associated autoimmune disease?	46
Molecular mechanism of cell ferroptosis and research progress in regulation of ferroptosis by noncoding RNAs in tumor cells	45
Platinum drugs and taxanes: can we overcome resistance?	44
METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice	44
The NSUN5-FTH1/FTL pathway mediates ferroptosis in bone marrow-derived mesenchymal stem cells	44
Non-coding RNAs in necroptosis, pyroptosis and ferroptosis in cancer metastasis	44