Nature Microbiology

Papers
(The TQCC of Nature Microbiology is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Gene–drug potency screening in M. tuberculosis582
Sickle cell trait enhances malaria transmission383
Metabolic sensing tips the balance of drug tolerance in fungal meningitis288
Author Correction: DART takes aim at community editing280
Rebound virus in the cerebrospinal fluid reveals a possible HIV-1 reservoir269
Molecular factors shaping whether HCMV infection is productive or latent267
Dietary exclusion of major food groups shapes the gut microbiome and may influence health266
The IFIT2–IFIT3 antiviral complex targets short 5’ untranslated regions on viral mRNAs for translation inhibition250
Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections221
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus215
Flipping the magic switch to persistence via GTP depletion214
Microbiome association with coral growth and survival213
Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host198
Mosquitoes provide a transmission route between possums and humans for Buruli ulcer in southeastern Australia190
Structure of a functional archaellum in Bacteria of the Chloroflexota phylum190
Double-stranded RNA sequencing reveals distinct riboviruses associated with thermoacidophilic bacteria from hot springs in Japan186
Cytoplasmic contractile injection systems mediate cell death in Streptomyces182
Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody182
The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation176
Host range, transmissibility and antigenicity of a pangolin coronavirus166
Horizontal gene transfer explains unusual traits of Armillaria fungi164
Single mutation makes Escherichia coli an insect mutualist164
The Parkinson’s disease drug entacapone disrupts gut microbiome homeostasis via iron sequestration162
A high-throughput and low-waste viability assay for microbes161
Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults161
The Mycobacterium tuberculosis protein O-phosphorylation landscape160
Ancient origin and constrained evolution of the division and cell wall gene cluster in Bacteria159
Organ-on-chip models for infectious disease research156
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING152
A dynamic subpopulation of CRISPR–Cas overexpressers allows Streptococcus pyogenes to rapidly respond to phage150
Recent gene selection and drug resistance underscore clinical adaptation across Candida species148
Therapeutic efficacy of monoclonal antibodies and antivirals against SARS-CoV-2 Omicron BA.1 in Syrian hamsters146
Climate extremes disrupt fungal–bacterial interactions146
OPENPichia: licence-free Komagataella phaffii chassis strains and toolkit for protein expression144
The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound140
Proteins containing photosynthetic reaction centre domains modulate FtsZ-based archaeal cell division139
Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome137
Particular genomic and virulence traits associated with preterm infant-derived toxigenic Clostridium perfringens strains137
Assessing critical thresholds in terrestrial microbiomes136
Explainable artificial intelligence evolves antimicrobial peptides134
Mycobacterium abscessus pathogenesis identified by phenogenomic analyses133
Exceeding expectations out in the cold with Colwellia132
CRISPR-influenced symbiosis130
Mineral-eating microorganisms at extinct hydrothermal vents130
Prioritizing mentorship129
Call for papers on the clinical microbiome126
Rational attenuation of RNA viruses with zinc finger antiviral protein123
Bacteroides fragilis uses toxins for gut success122
Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa120
Archaeal symbioses all the way down117
Extracellular vesicles block viral entryways117
Author Correction: A roadmap for equitable reuse of public microbiome data117
The complex path towards herpesvirus vaccines116
Pseudomonas syringae subpopulations cooperate by coordinating flagellar and type III secretion spatiotemporal dynamics to facilitate plant infection116
Risk–reward trade-off during carbon starvation generates dichotomy in motility endurance among marine bacteria115
Intragenic viral silencer element regulates HTLV-1 latency via RUNX complex recruitment114
Decoding the impact of nuclear organization on antigenic variation in parasites114
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2113
Streptomyces polyketides mediate bacteria–fungi interactions across soil environments111
Kaposi’s sarcoma-associated herpesvirus induces mitochondrial fission to evade host immune responses and promote viral production109
Blockade of endothelin receptors mitigates SARS-CoV-2-induced osteoarthritis108
Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration107
Coronavirus sampling and surveillance in bats from 1996–2019: a systematic review and meta-analysis107
Transforming tuberculosis diagnosis106
Expanding known viral diversity in the healthy infant gut106
SAMPL-seq reveals micron-scale spatial hubs in the human gut microbiome105
Structure-guided design of a synthetic bile acid that inhibits Clostridioides difficile TcdB toxin104
SARS and synapses102
Switching on cyclic di-GMP heterogeneity in Pseudomonas aeruginosa biofilms102
Placental Streptococcus agalactiae DNA is associated with neonatal unit admission and foetal pro-inflammatory cytokines in term infants102
Publisher Correction: Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis100
Genome-resolved metagenomics reveals microbiome diversity across 48 tick species100
From farm to factory to fork100
SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation100
Mycobacterium tuberculosis as teacher100
A nitrogen-fixing bacterium forms symbioses on land and at sea99
Precipitation legacy effects on soil microbiota facilitate adaptive drought responses in plants98
The gut–liver axis in HCV infection96
Using animation to mediate scientific discourse96
Hunting emerging viruses through participatory community science96
Non-canonical start codons confer context-dependent advantages in carbohydrate utilization for commensal E. coli in the murine gut94
CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state92
Parasite and vector circadian clocks mediate efficient malaria transmission91
Cell envelope diversity and evolution across the bacterial tree of life91
Characterization of inositol lipid metabolism in gut-associated Bacteroidetes91
Species- and site-specific genome editing in complex bacterial communities90
Connecting microbiome and menopause for healthy ageing89
An expanded metabolic pathway for androgen production by commensal bacteria88
Bacteriophages avoid autoimmunity from cognate immune systems as an intrinsic part of their life cycles88
Increased small particle aerosol transmission of B.1.1.7 compared with SARS-CoV-2 lineage A in vivo87
Harnessing the microbiome to prevent global biodiversity loss87
Self-assembling viral histones are evolutionary intermediates between archaeal and eukaryotic nucleosomes86
Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer83
Combining antibiotics to tackle antimicrobial resistance81
Outbreak dynamics of foodborne pathogen Vibrio parahaemolyticus over a seventeen year period implies hidden reservoirs81
Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia79
Sensitive poliovirus detection using nested PCR and nanopore sequencing: a prospective validation study79
Clinical implications of preterm infant gut microbiome development79
Discovery of an orally active benzoxaborole prodrug effective in the treatment of Chagas disease in non-human primates78
Phages with a broad host range are common across ecosystems77
Anoxia activates CRISPR–Cas immunity in the mouse intestine77
Dynamic diel proteome and daytime nitrogenase activity supports buoyancy in the cyanobacterium Trichodesmium76
Therapeutics for COVID-1976
Escherichia coli integrates chemotaxis and quorum sensing pathways in vivo75
A year of microbiology75
Bacteria can shed a layer when phages turn up the heat73
Mining the microbiota for antibiotics73
Siderophores mediate antibiotic resistance71
Activity-targeted metaproteomics uncovers rare syntrophic bacteria central to anaerobic community metabolism71
Non-equivalent genomes in polyploid prokaryotes71
Growth rate is modulated by monitoring cell wall precursors in Bacillus subtilis71
Reproductive justice must be considered in the scientific community71
Identified receptors shed light on Epstein–Barr virus infection71
mRNA-encoded Cas13 can be used to treat dengue infections in mice71
Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters70
Safety and immunogenicity of a prefusion non-stabilized spike protein mRNA COVID-19 vaccine: a phase I trial70
Bacteria modulate microalgal aging physiology through the induction of extracellular vesicle production to remove harmful metabolites70
A vision for spaceflight microbiology to enable human health and habitat sustainability69
Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts67
Microbial metabolites in the marine carbon cycle67
GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting66
Guiding phage therapy with genomic surveillance66
A framework for automated scalable designation of viral pathogen lineages from genomic data65
Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice64
TOLLIP inhibits lipid accumulation and the integrated stress response in alveolar macrophages to control Mycobacterium tuberculosis infection64
Mapping phyllosphere microbiota interactions in planta to establish genotype–phenotype relationships63
Inflammation-associated nitrate facilitates ectopic colonization of oral bacterium Veillonella parvula in the intestine63
The cell biology of archaea61
Widespread stop-codon recoding in bacteriophages may regulate translation of lytic genes61
STREAM-lining guidelines for microbiome research60
Parabacteroides distasonis uses dietary inulin to suppress NASH via its metabolite pentadecanoic acid60
Environmental stress mediates groundwater microbial community assembly60
Human microbiome myths and misconceptions60
Gut microbial factors predict disease severity in a mouse model of multiple sclerosis60
The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice60
Amplifying diverse voices in microbiology59
Vertical and horizontal gene transfer shaped plant colonization and biomass degradation in the fungal genus Armillaria59
Shining light on the coral photosymbiont family Symbiodiniaceae59
CD8+ T cell depletion does not induce an expansion of viral reservoir in HIV model59
We must learn from past outbreaks58
A method to detect origin of transfer sequences for plasmid conjugation58
Migrant health matters58
Molecular organization of the New World arenavirus spike glycoprotein complex58
Genome-wide protein–DNA interaction site mapping in bacteria using a double-stranded DNA-specific cytosine deaminase57
Sulfated glycosaminoglycans are host epithelial cell targets of the Candida albicans toxin candidalysin57
Retracing a tangled tree of archaeal evolution57
Multinational epidemiological analysis of oral human papillomavirus incidence in 3,137 men56
Addressing gaps in author and reviewer gender diversity56
Dairy cows develop protective immunity against reinfection with bovine H5N1 influenza virus56
Identifying an evolutionary origin for morbilliviruses in bats56
Inactivated whole-virion vaccine BBV152/Covaxin elicits robust cellular immune memory to SARS-CoV-2 and variants of concern56
SARS-CoV-2 Africa dashboard for real-time COVID-19 information56
Differential stress responsiveness determines intraspecies virulence heterogeneity and host adaptation in Listeria monocytogenes56
Diet switch pre-vaccination improves immune response and metabolic status in formerly obese mice56
Mycobacterial nucleoid-associated protein Lsr2 is required for productive mycobacteriophage infection55
Gut bacteria degrade purines via the 2,8-dioxopurine pathway55
Genomic epidemiology reveals multidrug resistant plasmid spread between Vibrio cholerae lineages in Yemen55
A haem-sequestering plant peptide promotes iron uptake in symbiotic bacteria55
Improving local prevalence estimates of SARS-CoV-2 infections using a causal debiasing framework55
Emergence of SARS-CoV-2 escape mutations during Bamlanivimab therapy in a phase II randomized clinical trial54
Metabolites from intact phage-infected Synechococcus chemotactically attract heterotrophic marine bacteria53
Comprehensive transcription terminator atlas for Bacillus subtilis53
Bacillus subtilis biofilm matrix components target seed oil bodies to promote growth and anti-fungal resistance in melon53
Tecovirimat is effective against human monkeypox virus in vitro at nanomolar concentrations53
Characterizing extracellular vesicles of human fungal pathogens53
The microbiome of a bacterivorous marine choanoflagellate contains a resource-demanding obligate bacterial associate51
Phase transition of GvpU regulates gas vesicle clustering in bacteria51
AMR, One Health and the environment51
Staphylococcal virulence factor HlgB targets the endoplasmic-reticulum-resident E3 ubiquitin ligase AMFR to promote pneumonia51
A phage-encoded anti-CRISPR protein co-opts host enolase to prevent type III CRISPR immunity51
Taurolithocholic acid protects against viral haemorrhagic fever via inhibition of ferroptosis51
BacterAI maps microbial metabolism without prior knowledge51
Preclinical evaluation of the SARS-CoV-2 Mpro inhibitor RAY1216 shows improved pharmacokinetics compared with nirmatrelvir51
Sex, gender and infectious disease50
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway50
Translating between science and politics as a government adviser50
Colonic goblet cell-associated antigen passages mediate physiologic and beneficial translocation of live gut bacteria in preweaning mice50
Iron-limitation light switch50
The human archaeome in focus50
Microbes and the water nexus50
Dipeptidase 1 is a functional receptor for a porcine coronavirus49
Understanding emerging and re-emerging viruses to facilitate pandemic preparedness49
The GATE glycoprotein complex enhances human cytomegalovirus entry in endothelial cells49
Chromosome architecture in an archaeal species naturally lacking structural maintenance of chromosomes proteins49
Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis49
Remote control designer probiotics48
Integrons are anti-phage defence libraries in Vibrio parahaemolyticus48
Clostridium sporogenes uses reductive Stickland metabolism in the gut to generate ATP and produce circulating metabolites48
Publisher Correction: Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission48
Longitudinal profiling of low-abundance strains in microbiomes with ChronoStrain48
Targeting the mosquito prefoldin–chaperonin complex blocks Plasmodium transmission48
Enterococcus faecalis-derived adenine enhances enterohaemorrhagic Escherichia coli Type 3 Secretion System-dependent virulence48
Nasal Staphylococcus aureus carriage promotes depressive behaviour in mice via sex hormone degradation48
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances47
Structural insights into light harvesting by antenna-containing rhodopsins in marine Asgard archaea47
A high-quality genome compendium of the human gut microbiome of Inner Mongolians46
Metabolic reprogramming enhances the susceptibility of multidrug- and carbapenem-resistant bacteria to antibiotics46
Understanding the biology of monkeypox virus to prevent future outbreaks46
Acquired amphotericin B resistance leads to fitness trade-offs that can be mitigated by compensatory evolution in Candida auris46
Carotenoids bind rhodopsins and act as photocycle-accelerating pigments in marine Bacteroidota46
Cooperative virulence via the collective action of secreted pathogen effectors46
MAP-X reveals distinct protein complex dynamics across Plasmodium falciparum blood stages45
Moving from hype to hope in diet–microbiome interactions45
Exploiting the fitness cost of metallo-β-lactamase expression can overcome antibiotic resistance in bacterial pathogens45
Metagenomic characterization of viruses and mobile genetic elements associated with the DPANN archaeal superphylum45
Author Correction: Arbuscular mycorrhizal fungi heterokaryons have two nuclear populations with distinct roles in host–plant interactions45
Talented microbes unlatch peatland carbon45
The host–parasite–virus triad45
Introducing Microbe Matters45
Dual inhibition of innate immunity and apoptosis by human cytomegalovirus protein UL37x1 enables efficient virus replication45
Factors associated with oral HPV infection among a large multinational cohort of men44
Small organisms with big climate impact44
A non-human primate model for human norovirus infection44
Viral biogeography of the mammalian gut and parenchymal organs43
Vientovirus capsid protein mimics autoantigens and contributes to autoimmunity in Sjögren’s disease43
Use microbes to tackle food insecurity43
Mycobiota and diet-derived fungal xenosiderophores promote Salmonella gastrointestinal colonization43
Discovery and artificial intelligence-guided mechanistic elucidation of a narrow-spectrum antibiotic43
Persistent viral RNA and protein contribute to post-acute pathology43
Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever43
Chromosome organization affects genome evolution in Sulfolobus archaea43
Identifying rare and active species that drive carbon turnover in complex microbiotas43
Microbiome–metabolite linkages drive greenhouse gas dynamics over a permafrost thaw gradient42
DMSOP-cleaving enzymes are diverse and widely distributed in marine microorganisms42
Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation42
CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery41
Evolution of SARS-CoV-2 in the murine central nervous system drives viral diversification41
FungAMR: a comprehensive database for investigating fungal mutations associated with antimicrobial resistance41
Intestinal crypt microbiota modulates intestinal stem cell turnover and tumorigenesis via indole acetic acid41
Microbiome alterations in autism spectrum disorder41
scRNA-seq reveals transcriptional plasticity of var gene expression in Plasmodium falciparum for host immune avoidance41
Drug–Fc conjugate CD388 targets influenza virus neuraminidase and is broadly protective in mice41
Parkinson’s disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella41
Gut microbiota-derived hexa-acylated lipopolysaccharides enhance cancer immunotherapy responses41
Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency41
Microplastic research must consider microbes41
Longitudinal population-level HIV epidemiologic and genomic surveillance highlights growing gender disparity of HIV transmission in Uganda41
Multigenerational proteolytic inactivation of restriction upon subtle genomic hypomethylation in Pseudomonas aeruginosa41
Chromosomal barcodes for simultaneous tracking of near-isogenic bacterial strains in plant microbiota41
Prediction of strain level phage–host interactions across the Escherichia genus using only genomic information41
Identification of structurally diverse menaquinone-binding antibiotics with in vivo activity against multidrug-resistant pathogens40
Structural insights into tecovirimat antiviral activity and poxvirus resistance40
Seed-borne bacteria drive wheat rhizosphere microbiome assembly via niche partitioning and facilitation40
Methane-dependent complete denitrification by a single Methylomirabilis bacterium40
Author Correction: Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut40
Leaf microbiome dysbiosis triggered by T2SS-dependent enzyme secretion from opportunistic Xanthomonas pathogens40
Redefining success39
Continental-scale associations of Arabidopsis thaliana phyllosphere members with host genotype and drought39
Knowledge synthesis through scientific visualization39
Connecting the dots from viral infection to disease39
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