OOIR: Observatory of International Research

Papers

(The TQCC of npj Regenerative Medicine is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Allogeneic RPE cell suspension manufactured at scale demonstrating preclinical safety and efficacy led to IND approval	94
Author Correction: Chondrogenic differentiation induced by extracellular vesicles bound to a nanofibrous substrate	79
Author Correction: The bright side of fibroblasts: molecular signature and regenerative cues in major organs	79
Combinatorial extracellular matrix tissue chips for optimizing mesenchymal stromal cell microenvironment and manufacturing	71
A ferret model demonstrates sustained fibrosis, restrictive physiology, and airway proximalization	68
Biological study of skin wound treated with Alginate/Carboxymethyl cellulose/chorion membrane, diopside nanoparticles, and Botox A	66
Micropattern-based nerve guidance conduit with hundreds of microchannels and stem cell recruitment for nerve regeneration	64
Supramolecular nanostructure mimics GDNF trophic effects in vitro on human dopaminergic neurons	64
Proteomic profiling of iPSC and tissue-derived MSC secretomes reveal a global signature of inflammatory licensing	58
Modulating the platelet-mediated innate foreign body response to affect in situ vascular tissue engineering outcomes	56
Implication of CXCR2-Src axis in the angiogenic and osteogenic effects of FP-TEB	47
Non-canonical muscle stem cells and other lessons from regenerative vertebrates	42
Airway epithelial cell identity and plasticity are constrained by Sox2 during lung homeostasis, tissue regeneration, and in human disease	38
Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms	37
The MRN complex maintains the biliary-derived hepatocytes in liver regeneration through ATR-Chk1 pathway	37
Therapeutic-delivering endotracheal tubes heal intubation injury via mucosal remodeling and disrupting the inflammation-microbiome-fibrosis triad	36
An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration	36
Skeletal muscle regeneration after extensive cryoinjury of caudal myomeres in adult zebrafish	36
Comparison studies identify mesenchymal stromal cells with potent regenerative activity in osteoarthritis treatment	35
Bio-orthogonal crosslinking and hyaluronan facilitate transparent healing after treatment of deep corneal injuries with in situ-forming hydrogels	34
Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy	33
Infected wound repair correlates with collagen I induction and NOX2 activation by cold atmospheric plasma	33
Scale up manufacturing approach for production of human induced pluripotent stem cell-derived islets using Vertical Wheel® bioreactors	31
Tie2-enriched nucleus pulposus cell transplantation enables severity-independent disc repair in a canine model with induced and controlled disc degeneration severity	31
TGF-alpha/EGFR signalling mediates retinoic acid-induced lung repair	31

Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence	31
Harnessing bioengineered myeloid progenitors for precision immunotherapies	30
Telomere shortening in laminopathic dilated cardiomyopathy	29
Calorie restriction and rapamycin distinctly restore non-canonical ORF translation in the muscles of aging mice	29
Immunomodulatory and anabolic biphasic scaffold with hierarchical biomimetic structure directed osteochondral defect repair	29
Type V collagen from macrophages regulates initial collagen assembly and alignment in post-infarcted hearts	28
Inflammation-suppressing cornea-in-a-syringe with anti-viral GF19 peptide promotes regeneration in HSV-1 infected rabbit corneas	27
Modulating Schwann cell behavior via functional nerve guidance conduits for enhanced peripheral nerve regeneration	27
Exploiting in silico modelling to enhance translation of liver cell therapies from bench to bedside	26
Adipose-derived dual cell therapy enhances arteriogenesis and limb preservation through vascular integration in critical limb ischemia	26
Direct reprogramming of mouse fibroblasts into self-renewable alveolar epithelial-like cells	26
MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice	26
A short dasatinib and quercetin treatment is sufficient to reinstate potent adult neuroregenesis in the aged killifish	26
Engraftment of wild-type alveolar type II epithelial cells in surfactant protein C deficient mice	25
Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche	25
Food-derived peptide RDP3 mitigates pyroptosis to enhance oral mucosal repair via the IL-2Rβ/PI3K axis	25
BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization	24
Leiomodin 2 neonatal dilated cardiomyopathy mutation results in altered actin gene signatures and cardiomyocyte dysfunction	24
Scaffolds with spatiotemporally controlled growth factor delivery and cyclodextrin-enabled antagonism of growth factor receptor sequestration promote cutaneous wound healing	24
Clinically relevant small-molecule promotes nerve repair and visual function recovery	24
Regeneration-specific promoter switching facilitates Mest expression in the mouse digit tip to modulate neutrophil response	23
Impaired bone healing upon neutrophil-specific adrenoreceptor beta 2 knockout in non-osteoporotic and osteoporotic mice	22
Epimorphic regeneration in the mammalian tympanic membrane	22
Chitosan-fibrinogen-thrombin matrix accelerates re-epithelialization and cornification in a rat wound healing model	22
Optical mapping of the interface between iPSC-derived grafts and swine myocardium suggests potential arrhythmia mechanisms	21
Co-transplantation of pancreatic islets and microvascular fragments effectively restores normoglycemia in diabetic mice	21
Transplantation of derivative retinal organoids from chemically induced pluripotent stem cells restored visual function	20
Stem cell-derived extracellular vesicles and artificial nanovesicles: a translational framework for cell-free wound repair	20
Immunomodulation by the combination of statin and matrix-bound nanovesicle enhances optic nerve regeneration	20
Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration	20
Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs	20
Local BMP2 hydrogel therapy for robust bone regeneration in a porcine model of Legg-Calvé-Perthes disease	20
A computational model reveals an early transient decrease in fiber cross-linking that unlocks adult regeneration	19
Macrophage-based therapy for intervertebral disc herniation: preclinical proof-of-concept	19
Endogenous tenocyte activation underlies the regenerative capacity of the adult zebrafish tendon	19
Author Correction: Disease exacerbation in human DMD MYOrganoids enables gene therapy evaluation and unveils persistence of fibrotic activity	19
Heart ventricle regeneration in the lizard Eublepharis macularius, the leopard gecko	19
Author Correction: Patients seeking stem cell therapies—a prospective qualitative analysis from a Regenerative Medicine Consult Service	18
Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells	18
A STAT5-Smad3 dyad regulates adipogenic plasticity of visceral adipose mesenchymal stromal cells during chronic inflammation	18
Cyclin A2 induces cytokinesis in human adult cardiomyocytes and drives reprogramming in mice	18