OOIR: Observatory of International Research

Papers

(The TQCC of npj Regenerative Medicine is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Author Correction: Chondrogenic differentiation induced by extracellular vesicles bound to a nanofibrous substrate	74
Allogeneic RPE cell suspension manufactured at scale demonstrating preclinical safety and efficacy led to IND approval	72
Supramolecular nanostructure mimics GDNF trophic effects in vitro on human dopaminergic neurons	72
Proteomic profiling of iPSC and tissue-derived MSC secretomes reveal a global signature of inflammatory licensing	60
Author Correction: The bright side of fibroblasts: molecular signature and regenerative cues in major organs	60
Combinatorial extracellular matrix tissue chips for optimizing mesenchymal stromal cell microenvironment and manufacturing	59
Biological study of skin wound treated with Alginate/Carboxymethyl cellulose/chorion membrane, diopside nanoparticles, and Botox A	49
A ferret model demonstrates sustained fibrosis, restrictive physiology, and airway proximalization	48
Micropattern-based nerve guidance conduit with hundreds of microchannels and stem cell recruitment for nerve regeneration	46
Bio-orthogonal crosslinking and hyaluronan facilitate transparent healing after treatment of deep corneal injuries with in situ-forming hydrogels	45
Modulating the platelet-mediated innate foreign body response to affect in situ vascular tissue engineering outcomes	45
Infected wound repair correlates with collagen I induction and NOX2 activation by cold atmospheric plasma	44
Comparison studies identify mesenchymal stromal cells with potent regenerative activity in osteoarthritis treatment	41
Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms	40
Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy	40
Airway epithelial cell identity and plasticity are constrained by Sox2 during lung homeostasis, tissue regeneration, and in human disease	39
An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration	38
Skeletal muscle regeneration after extensive cryoinjury of caudal myomeres in adult zebrafish	37
Implication of CXCR2-Src axis in the angiogenic and osteogenic effects of FP-TEB	35
The MRN complex maintains the biliary-derived hepatocytes in liver regeneration through ATR-Chk1 pathway	34
Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence	33
Exploiting in silico modelling to enhance translation of liver cell therapies from bench to bedside	30
Type V collagen from macrophages regulates initial collagen assembly and alignment in post-infarcted hearts	29
Harnessing bioengineered myeloid progenitors for precision immunotherapies	28
Scale up manufacturing approach for production of human induced pluripotent stem cell-derived islets using Vertical Wheel® bioreactors	27

Calorie restriction and rapamycin distinctly restore non-canonical ORF translation in the muscles of aging mice	27
Inflammation-suppressing cornea-in-a-syringe with anti-viral GF19 peptide promotes regeneration in HSV-1 infected rabbit corneas	27
Proteoglycan 4 (PRG4) treatment enhances wound closure and tissue regeneration	26
Modulating Schwann cell behavior via functional nerve guidance conduits for enhanced peripheral nerve regeneration	26
MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice	25
A short dasatinib and quercetin treatment is sufficient to reinstate potent adult neuroregenesis in the aged killifish	25
Clinically relevant small-molecule promotes nerve repair and visual function recovery	24
Scaffolds with spatiotemporally controlled growth factor delivery and cyclodextrin-enabled antagonism of growth factor receptor sequestration promote cutaneous wound healing	24
Leiomodin 2 neonatal dilated cardiomyopathy mutation results in altered actin gene signatures and cardiomyocyte dysfunction	24
Hippo-Yap/Taz signalling in zebrafish regeneration	24
Direct reprogramming of mouse fibroblasts into self-renewable alveolar epithelial-like cells	24
Immunomodulation by the combination of statin and matrix-bound nanovesicle enhances optic nerve regeneration	23
BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization	23
Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs	23
Epimorphic regeneration in the mammalian tympanic membrane	23
The specialist in regeneration—the Axolotl—a suitable model to study bone healing?	23
Transplantation of derivative retinal organoids from chemically induced pluripotent stem cells restored visual function	22
Optical mapping of the interface between iPSC-derived grafts and swine myocardium suggests potential arrhythmia mechanisms	22
Regeneration-specific promoter switching facilitates Mest expression in the mouse digit tip to modulate neutrophil response	21
Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells	21
A computational model reveals an early transient decrease in fiber cross-linking that unlocks adult regeneration	21
Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration	21
Co-transplantation of pancreatic islets and microvascular fragments effectively restores normoglycemia in diabetic mice	21
Endogenous tenocyte activation underlies the regenerative capacity of the adult zebrafish tendon	20
Macrophage-based therapy for intervertebral disc herniation: preclinical proof-of-concept	20
Cyclin A2 induces cytokinesis in human adult cardiomyocytes and drives reprogramming in mice	20
Sonic Hedgehog acts as a macrophage chemoattractant during regeneration of the gastric epithelium	20
Regeneration of tracheal neotissue in partially decellularized scaffolds	18
Local BMP2 hydrogel therapy for robust bone regeneration in a porcine model of Legg-Calvé-Perthes disease	18
Author Correction: Patients seeking stem cell therapies—a prospective qualitative analysis from a Regenerative Medicine Consult Service	18
Immunomodulatory matrix-bound nanovesicles mitigate acute and chronic pristane-induced rheumatoid arthritis	18
Structural, angiogenic, and immune responses influencing myocardial regeneration: a glimpse into the crucible	18
Author Correction : SUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington’s disease	18
OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease	17
Immune-mediated regeneration of cell-free vascular grafts in an ovine model	17
Author Correction: Capacitive interdigitated system of high osteoinductive/conductive performance for personalized acting-sensing implants	17
A STAT5-Smad3 dyad regulates adipogenic plasticity of visceral adipose mesenchymal stromal cells during chronic inflammation	17
Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart	17
Preclinical efficacy and safety of AAVrh10-based plakophilin-2 gene therapy (LX2020) as a treatment for arrhythmogenic cardiomyopathy	17
Dynamics of skeletal muscle-resident stem cells during myogenesis in fibrodysplasia ossificans progressiva	17