OOIR: Observatory of International Research

Papers

(The TQCC of npj Regenerative Medicine is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Mitochondrial dysfunction in neurological disorders: Exploring mitochondrial transplantation	136
Global trends in clinical trials involving pluripotent stem cells: a systematic multi-database analysis	94
Heterogeneity of mesenchymal stem cells in cartilage regeneration: from characterization to application	85
Scaffold-free cell-based tissue engineering therapies: advances, shortfalls and forecast	70
Self-assembling peptide scaffolds in the clinic	63
The bright side of fibroblasts: molecular signature and regenerative cues in major organs	58
Neural stem cell delivery via porous collagen scaffolds promotes neuronal differentiation and locomotion recovery in spinal cord injury	58
Towards stem cell therapies for skeletal muscle repair	57
Immune modulation of hair follicle regeneration	56
Longevity leap: mind the healthspan gap	54
Cellular human tissue-engineered skin substitutes investigated for deep and difficult to heal injuries	54
Innervation: the missing link for biofabricated tissues and organs	53
Dedifferentiation: inspiration for devising engineering strategies for regenerative medicine	48
Next generation of heart regenerative therapies: progress and promise of cardiac tissue engineering	48
Preclinical assessment on neuronal regeneration in the injury-related microenvironment of graphene-based scaffolds	48
Overcoming kidney organoid challenges for regenerative medicine	48
Small extracellular vesicles derived from interferon-γ pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis	46
Insights into the use of mesenchymal stem cells in COVID-19 mediated acute respiratory failure	45
Macrophages in heterotopic ossification: from mechanisms to therapy	43
Challenges and translational considerations of mesenchymal stem/stromal cell therapy for Parkinson’s disease	42
Senolytics improve bone forming potential of bone marrow mesenchymal stem cells from aged mice	41
Human gingival fibroblast secretome accelerates wound healing through anti-inflammatory and pro-angiogenic mechanisms	38
The evolving definition of salivary gland stem cells	35
Skeletal muscle differentiation of human iPSCs meets bioengineering strategies: perspectives and challenges	34
The jam session between muscle stem cells and the extracellular matrix in the tissue microenvironment	34

3D in vitro M2 macrophage model to mimic modulation of tissue repair	33
Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin	32
Regenerative medicine meets mathematical modelling: developing symbiotic relationships	29
Updates on clinical trials evaluating the regenerative potential of allogenic mesenchymal stem cells in COVID-19	29
Optimizing maturity and dose of iPSC-derived dopamine progenitor cell therapy for Parkinson’s disease	28
VEGF-A, PDGF-BB and HB-EGF engineered for promiscuous super affinity to the extracellular matrix improve wound healing in a model of type 1 diabetes	27
The Warburg effect is necessary to promote glycosylation in the blastema during zebrafish tail regeneration	27
Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling	25
Nerve-specific extracellular matrix hydrogel promotes functional regeneration following nerve gap injury	25
Cellularized small-caliber tissue-engineered vascular grafts: looking for the ultimate gold standard	24
Matrilin3/TGFβ3 gelatin microparticles promote chondrogenesis, prevent hypertrophy, and induce paracrine release in MSC spheroid for disc regeneration	24
The genetic basis of inter-individual variation in recovery from traumatic brain injury	24
Metformin accelerates zebrafish heart regeneration by inducing autophagy	23
The clinical potential of articular cartilage-derived progenitor cells: a systematic review	23
Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing	23
TP63 basal cells are indispensable during endoderm differentiation into proximal airway cells on acellular lung scaffolds	23
Targets identified from exercised heart: killing multiple birds with one stone	22
Hemodynamic performance of tissue-engineered vascular grafts in Fontan patients	21
Personalized medicine for reconstruction of critical-size bone defects – a translational approach with customizable vascularized bone tissue	20
Immunomodulation for optimal cardiac regeneration: insights from comparative analyses	19
An immunologically active, adipose-derived extracellular matrix biomaterial for soft tissue reconstruction: concept to clinical trial	19
Mussel-inspired multifunctional surface through promoting osteogenesis and inhibiting osteoclastogenesis to facilitate bone regeneration	19
Notch-Wnt signal crosstalk regulates proliferation and differentiation of osteoprogenitor cells during intramembranous bone healing	19
Looking backward to move forward: a meta-analysis of stem cell therapy in amyotrophic lateral sclerosis	18
Neutrophil extracellular traps promote scar formation in post-epidural fibrosis	18
Injectable decellularized cartilage matrix hydrogel encapsulating urine-derived stem cells for immunomodulatory and cartilage defect regeneration	18
Current progress of rehabilitative strategies in stem cell therapy for spinal cord injury: a review	18
Modeling PRPF31 retinitis pigmentosa using retinal pigment epithelium and organoids combined with gene augmentation rescue	16
A bioinspired gelatin-hyaluronic acid-based hybrid interpenetrating network for the enhancement of retinal ganglion cells replacement therapy	16
Mammals fail to regenerate organs when wound contraction drives scar formation	16
Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis	15
Induced pluripotency in the context of stem cell expansion bioprocess development, optimization, and manufacturing: a roadmap to the clinic	15
Ultrasound-guided platelet-rich plasma injection and multimodality ultrasound examination of peripheral nerve crush injury	15
Safety and efficacy of human juvenile chondrocyte-derived cell sheets for osteochondral defect treatment	15
FGF2-primed 3D spheroids producing IL-8 promote therapeutic angiogenesis in murine hindlimb ischemia	15
Stem cell-based therapy for COVID-19 and ARDS: a systematic review	15
Immunomodulatory matrix-bound nanovesicles mitigate acute and chronic pristane-induced rheumatoid arthritis	15
The potential utility of hybrid photo-crosslinked hydrogels with non-immunogenic component for cartilage repair	14
Chondrogenic primed extracellular vesicles activate miR-455/SOX11/FOXO axis for cartilage regeneration and osteoarthritis treatment	14
Ischemic tolerance and cardiac repair in the spiny mouse (Acomys)	14
Vitrification of particulated articular cartilage via calculated protocols	14
Systematic review and meta-analysis of preclinical studies testing mesenchymal stromal cells for traumatic brain injury	14
Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration	14
Capacitive interdigitated system of high osteoinductive/conductive performance for personalized acting-sensing implants	14
3D bioprinting using a new photo-crosslinking method for muscle tissue restoration	14
Mitochondrial augmentation of CD34+ cells from healthy donors and patients with mitochondrial DNA disorders confers functional benefit	14
Vasculogenesis in kidney organoids upon transplantation	14