OOIR: Observatory of International Research

Papers

(The H4-Index of npj Systems Biology and Applications is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Measuring criticality in control of complex biological networks	63
Severe testing with high-dimensional omics data for enhancing biomedical scientific discovery	60
Data-driven modeling of core gene regulatory network underlying leukemogenesis in IDH mutant AML	51
Spatial computational modelling illuminates the role of the tumour microenvironment for treating glioblastoma with immunotherapies	44
Olfactory receptors contribute to progression of kidney fibrosis	43
Leveraging public AI tools to explore systems biology resources in mathematical modeling	41
Comprehensive molecular interaction map of TGFβ induced epithelial to mesenchymal transition in breast cancer	38
Causality-aware graph neural networks for functional stratification and phenotype prediction at scale	34
Sunset Yellow protects against oxidative damage and exhibits chemoprevention in chemically induced skin cancer model	33
Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control	33
Transcriptome analysis of clock disrupted cancer cells reveals differential alternative splicing of cancer hallmarks genes	32
Knowledge-based mechanistic modeling accurately predicts disease progression with gefitinib in EGFR-mutant lung adenocarcinoma	31
Author Correction: Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms	31
Network-based transfer of pan-cancer immunotherapy responses to guide breast cancer prognosis	29
Classification of NSCLC subtypes using lung microbiome from resected tissue based on machine learning methods	29
Modelling HIV-1 control and remission	25
Leveraging quantitative systems pharmacology modeling for elranatamab regimen optimization in relapsed or refractory multiple myeloma	24
Quantitative cancer-immunity cycle modeling for predicting disease progression in advanced metastatic colorectal cancer	23
Understanding the role of toggle genes in chronic lymphocytic leukemia proliferation	23
Integrative temporal multi-omics reveals uncoupling of transcriptome and proteome during human T cell activation	23
Revisiting the evolution of bow-tie architecture in signaling networks	22
Tissue-wide cell-specific proteogenomic modeling reveals novel candidate risk genes in autism spectrum disorders	22