OOIR: Observatory of International Research

Papers

(The H4-Index of npj Systems Biology and Applications is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Sunset Yellow protects against oxidative damage and exhibits chemoprevention in chemically induced skin cancer model	70
Knowledge-based mechanistic modeling accurately predicts disease progression with gefitinib in EGFR-mutant lung adenocarcinoma	61
Spatial computational modelling illuminates the role of the tumour microenvironment for treating glioblastoma with immunotherapies	50
Measuring criticality in control of complex biological networks	41
Severe testing with high-dimensional omics data for enhancing biomedical scientific discovery	39
Transcriptome analysis of clock disrupted cancer cells reveals differential alternative splicing of cancer hallmarks genes	38
Data-driven modeling of core gene regulatory network underlying leukemogenesis in IDH mutant AML	36
Leveraging public AI tools to explore systems biology resources in mathematical modeling	34
Comprehensive molecular interaction map of TGFβ induced epithelial to mesenchymal transition in breast cancer	34
Olfactory receptors contribute to progression of kidney fibrosis	32
Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control	30
Network-based transfer of pan-cancer immunotherapy responses to guide breast cancer prognosis	28
Integrative temporal multi-omics reveals uncoupling of transcriptome and proteome during human T cell activation	27
Revisiting the evolution of bow-tie architecture in signaling networks	27
Quantitative cancer-immunity cycle modeling for predicting disease progression in advanced metastatic colorectal cancer	23
Author Correction: Computer modeling defines the system driving a constant current crucial for homeostasis in the mammalian cochlea by integrating unique ion transports	22
Classification of NSCLC subtypes using lung microbiome from resected tissue based on machine learning methods	22
Tissue-wide cell-specific proteogenomic modeling reveals novel candidate risk genes in autism spectrum disorders	22
Modelling HIV-1 control and remission	21
Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbiosis	21
Integrated omics of Saccharomyces cerevisiae CENPK2-1C reveals pleiotropic drug resistance and lipidomic adaptations to cannabidiol	20
sciCAN: single-cell chromatin accessibility and gene expression data integration via cycle-consistent adversarial network	20