OOIR: Observatory of International Research

Papers

(The H4-Index of npj Systems Biology and Applications is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery	69
Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbiosis	53
Nobel Turing Challenge: creating the engine for scientific discovery	47
Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection	34
Sparsely-connected autoencoder (SCA) for single cell RNAseq data mining	33
Crosstalk between Plk1, p53, cell cycle, and G2/M DNA damage checkpoint regulation in cancer: computational modeling and analysis	31
Adaptive coding for DNA storage with high storage density and low coverage	31
High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures	30
Cell morphology-based machine learning models for human cell state classification	29
Computational systems biology in disease modeling and control, review and perspectives	25
The in vitro micronucleus assay using imaging flow cytometry and deep learning	24
Integrative computational approach identifies drug targets in CD4+ T-cell-mediated immune disorders	23
An expanded whole-cell model of E. coli links cellular physiology with mechanisms of growth rate control	21
Application of physiologically based pharmacokinetic modeling for sertraline dosing recommendations in pregnancy	19
Systems modeling predicts that mitochondria ER contact sites regulate the postsynaptic energy landscape	19
Predicted ‘wiring landscape’ of Ras-effector interactions in 29 human tissues	19
Constructing gene regulatory networks using epigenetic data	18
Metabolic modeling of host–microbe interactions for therapeutics in colorectal cancer	18
Optimal proteome allocation and the temperature dependence of microbial growth laws	18
Metabolomics and transcriptomics based multi-omics integration reveals radiation-induced altered pathway networking and underlying mechanism	18