Global Challenges

Article	Citations
Lipid Nanoparticle (LNP) ‐A Vector Suitable for Evolving Therapies for Advanced Hepatocellular Carcinoma (HCC)	286
Techno−Economic Analysis and Multi‐Objective Optimization of Cross‐Flow Wind Turbines for Smart Building Energy Systems	131
Masthead: (Global Challenges 4/2023)	121
Kinetic Insights into Methanol Synthesis from CO2 Hydrogenation at Atmospheric Pressure over Intermetallic Pd2Ga Catalyst	118
Tannin: An Insight into its Cosmeceutical Properties and Uses (Global Challenges 8/2025)	84
Issue Information	84
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Functionalized MoO3 Nanosheets for High‐Efficiency RhB Removal	73
A Review of Floating Photovoltaic Systems: Prospects, Challenges, and Sustainability Considerations	68
Assessment of Odor Removal in Rigid Polypropylene Waste: Comprehensive Characterization and Washing Comparison	68
Towards Sustainable Development Goals: Application of Hydrogen‐Enriched Mahua Biodiesel/Diesel Blend to Dual‐Fuel Diesel Engine	53
Blue Light Defocus Induces A Positive Effect on Refractive Status and Ocular Health: A Randomized Crossover Trial	50
From Waste to Resource: Reframing End‐of‐Life Materials for a Circular Future	49
Strawberry Protease as a Laundry Detergent Additive Candidate: Immobilization, Compatibility Study with Detergent Ingredients, and Washing Performance Test	47
Issue Information	39
Nanocomposites for Water Treatment, Photocatalysis, and Challenges: A Systematic Review	39
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Observed Hydroclimatic Trends and Their Implications Over Water‐Cycle Dynamics in Montérégie, Southern Quebec, Canada	35
Issue Information	34
CeO2 Nanoparticles Seed Priming Increases Salicylic Acid Level and ROS Scavenging Ability to Improve Rapeseed Salt Tolerance (Global Challenges 7/2022)	33
Assembling the climate story: use of storyline approaches in climate‐related science	31
Green Coffee Bean Extract Assisted Facile Synthesis of Reduced Graphene Oxide and Its Dye Removal Activity	31
Toward Zero Waste Mining: Circular Economy of Copper Slags	31
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Experimental Analysis of Combustion and Emission Characteristics of a Diesel Engine Using Diesel‐Biodiesel‐Methanol Blends With Cetane Enhancer Additive Under Pilot Injection Mode	28
Advances in Nanohybrid Membranes for Dye Reduction: A Comprehensive Review	27
Rivers of Tears – Convergent, Multi‐Scale Approaches to Monitor and Optimize the Health of Our World's Inhabitants	25
Lightweight Natural Fiber Insulation Boards Produced with Kapok Fiber (Ceiba Pentandra) and Polylactic Acid or Bicomponent Fiber as a Binder	25
A Solar to Chemical Strategy: Green Hydrogen as a Means, Not an End	25
Sustainable Strategies for Converting Organic, Electronic, and Plastic Waste From Municipal Solid Waste Into Functional Materials	24
Techno‐Economic and Profitability Assessment of Stand‐Alone Photoelectrochemical Hydrogen Generation Technology	24
Comparative Study of the Effective Properties of 0–3 and Gyroid Triply Periodic Minimal Surface Cement‐Piezocomposites	23
Determination of Groundwater Vulnerability for Protection of the Drinking Water Basins: A Case Study From Türkiye, Kesikköprü Dam Lake Basin	23
Integrated In Silico – In Vitro Study Investigating Dipeptides as Chorismate Synthase Modulators: Spotlight on Its Mechanism of Action	23
A Perspective on Removal of Cyanotoxins from Water Through Advanced Oxidation Processes	23
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Bioinspired Interfacial Spontaneous Growth of ZnO Nanocatalysts onto Recycled Textiles as a Sustainable Approach for Water Purification	21
Production and Characterization of Open Cell Cordierite from Boron and Waste Materials by Geopolymer Method for the Emission After Treatment System of Diesel Engines	21
Measurement of Carbon Emission Transfer in China's Construction Industry and Analysis of Spatial and Temporal Distribution of Carbon Emissions	21
Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review	21
Pioneering an Innovative Eco‐Friendly N719 Dye‐Sensitized Solar Cell through Modelling and Impedance Spectroscopy Analysis for Energy Sustainability	21
CytroCell@Nafion: Enhanced Proton Exchange Membranes	21
Targeted Crystallization of Rare Earth Carbonate Polymorphs at Hydrothermal Conditions via Mineral Replacement Reactions	19
Masthead: (Global Challenges 9/2022)	19
New Insight into Mercury Removal from Fish Meat Using a Single‐Component Solution Containing cysteine	19
Waste to Wealth: Electrochemical Innovations in Hydrogen Production From Industrial Wastewater	19
Issue Information	18
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Spatial Analysis of Agricultural Waste and By‐Products to Tackle the Water–Energy Nexus in Rural Mozambique	18
Vanillin‐Derived Thermally Reprocessable and Chemically Recyclable Schiff‐Base Epoxy Thermosets	18
A Long‐Lasting Skin Protectant Based on CG‐101, a Deep Eutectic Solvent Comprising Choline and Geranic Acid	17
Spatio‐Temporal Modeling of Land‐Use/Land‐Cover Change and Land Surface Temperature Using SVM and CA–Markov in Dilla Town, Ethiopia	17
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Advances and Applications of Metal‐Organic Frameworks (MOFs) in Emerging Technologies: A Comprehensive Review	16
Biomedical Big Data Technologies, Applications, and Challenges for Precision Medicine: A Review	16
Biodegradation in Composting Conditions of PBEAS Monofilaments for the Sustainable End‐Use of Fishing Nets	16
Challenges in Recycling Spent Lithium‐Ion Batteries: Spotlight on Polyvinylidene Fluoride Removal	16
Issue Information	15
(Global Challenges 5/2023)	15
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(Global Challenges 8/2023)	15
Photoelectrocatalysis for Hydrogen Evolution Ventures into the World of Organic Synthesis	14
From Lab to Field: Damp Heat Testing and its Implications for PV Module Service Lifetime	14
Issue Information	14
Energy Sources and Thermal Management Technologies for Electric Vehicle Batteries: A Technical Review	14
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Sustainable Hydrogen Production, a Review of Methods, Types, Applications, Challenges, and Future Perspectives	13
Future Energy Breakthroughs: Implications for the Hydrocarbon Economies of the Arabian Gulf	13
Dye Degradation, Antimicrobial Activity, and Molecular Docking Analysis of Samarium‐Grafted Carbon Nitride Doped‐Bismuth Oxobromide Quantum Dots	12
Masthead: (Global Challenges 1/2023)	12
Computational Perspectives on Amoxicillin and Staphylococcus Aureus in Mirror Life	12
Alpha‐Gal Syndrome: An Underrated Serious Disease and a Potential Future Challenge	12

Synergetic Benefits of Agricultural Sewage Reuse and Floating Photovoltaics in Mexican Wastewater System: A Municipal‐Level WEF Nexus Study	12
CytroCell@Nafion: Enhanced Proton Exchange Membranes (Global Challenges 12/2025)	12
Parameter Extraction of Single, Double, and Triple‐Diode Photovoltaic Models Using the Weighted Leader Search Algorithm	11
Medication, Nutrition, and Hygiene in COVID‐19 Prevention and Treatment: A Comprehensive Narrative Review	11
Pinaceae Pine Resins (Black Pine, Shore Pine, Rosin, and Baltic Amber) as Natural Dielectrics for Low Operating Voltage, Hysteresis‐Free, Organic Field Effect Transistors	11
Non‐ Conventional Agents Enhance Sweet Pepper ( Capsicum annuum L. var. annuum ) Defense against	11
ALA‐A2 Is a Novel Anticancer Peptide Inspired by Alpha‐Lactalbumin: A Discovery from a Computational Peptide Library, In Silico Anticancer Peptide Screening and In Vitro Experimental Validation	11
Thermally Conductive Molten Salt for Thermal Energy Storage: Synergistic Effect of a Hybrid Graphite‐Graphene Nanoplatelet Filler	11
Opportunities and Challenges of Establishing a Regional Bio‐based Polylactic Acid Supply Chain (Global Challenges 7/2023)	11
The Fragile State of Industrial Agriculture: Estimating Crop Yield Reductions in a Global Catastrophic Infrastructure Loss Scenario	11
Blue Light Defocus Induces A Positive Effect on Refractive Status and Ocular Health: A Randomized Crossover Trial (Global Challenges 12/2025)	10
Current Challenges in Efficient Lithium‐Ion Batteries’ Recycling: A Perspective	10
Adapting Neutralizing Antibodies to Viral Variants by Structure‐Guided Affinity Maturation Using Phage Display Technology	10
Tunable Fungal Monofilaments from Food Waste for Textile Applications	10
Reusable and Antibacterial Polymer‐Based Nanocomposites for the Adsorption of Dyes and the Visible‐Light‐Driven Photocatalytic Degradation of Antibiotics	10
Time‐Quantile and Frequency Response of Green Growth to Energy Vulnerability, Energy Uncertainty, and Geopolitical Risks	10
Issue Information	9
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Modeling and Thermodynamic Studies of γ‐Valerolactone Production from Bio‐derived Methyl Levulinate	9
Short‐Term Effect of Air Pollution on Out of Hospital Cardiac Arrest (OHCA) in Lombardy—A Case‐Crossover Spatiotemporal Study	9
Sustainable LC3 Concrete in the Circular Economy: Assessment of Mechanical, Microstructural, and Durability Characteristics with Surkhi, Metakaolin, Nano‐Silica, and M‐Sand Blended Concrete	9
Fates of Emitted Particles Depending on Mask Wearing Using an Approach Validated Across Spatial Scales	9
Microplastics in Malaysia's Aquatic Environment: Current Overview and Future Perspectives	9
Random Access Memory (RAM) Contacts Waste Catalyzes Organic Reactions	9
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Magnetite Nanoparticles Enhancing H2‐Driven Biomethanation in a Mixed Microbial Community	9
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TiO 2 Bowl‐Like Nanocavity With Inner Au Embedded for Visible‐Light Photocatalysis	8
Harnessing Cattail Biomass for Sustainable Fibers and Engineered Bioproducts: A Review	8
Big Things, Small Packages: An Update on Microalgae as Sustainable Sources of Nutraceutical Peptides for Promoting Cardiovascular Health	8
Plant Growth‐Promoting Rhizobacteria and Bacterial Biocontrol Agents in Tomato Disease Management: Mechanisms, Applications, and Omics Perspectives	8
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Influence of Coal Gangue Powder on the Macroscopic Mechanical Properties and Microstructure of Recycled Aggregate Concrete	8
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Recycling and Degradation Pathways of Synthetic Textile Fibers such as Polyamide and Elastane	8
Research on the Development of Rural Human Settlement Environment in the Upper Reaches of the Lancang River Based on Ecological Carrying Capacity Constraints	8
Marketing Strategies in Nanomaterials for Sensor Applications: Bridging Lab to Market	8
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Microbial Desalination Cell for Sustainable Water Treatment: A Critical Review	8
Toward Sustainability in Cardiac Tissue Engineering: Electrospun Polyurethane Scaffolds Functionalized With Lemon‐Derived Bioactives	8
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Recent Progress of Droplet Microfluidic Emulsification Based Synthesis of Functional Microparticles	8
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(Global Challenges 6/2023)	7
Mitigating Urban Heat Islands (UHI) Through Vegetation Restoration: Insights From Mining Communities	7
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Degradation of Orange G, Acid Blue 161, and Brillant Green Dyes Using UV Light‐Activated GA–TiO2–Cd Composite	7
An In‐Silico Study to Identify Relevant Biomarkers in Sepsis Applying Integrated Bulk RNA Sequencing and Single‐Cell RNA Sequencing Analyses	7
Solar Drying for Domestic and Industrial Applications: A Comprehensive Review of Innovations and Efficiency Enhancements	7
Cancer‐Derived Extracellular Vesicle ITGB2 Promotes the Progression of Triple‐Negative Breast Cancer via the Activation of Cancer‐Associated Fibroblasts	7
Smart and Sustainable Regeneration of Fouled Desalination Membranes Using Artificial Intelligence	7
A Trihybrid Approach for Enhancing Crude Oil Recovery Using Effervescent‐Tablet‐Based Nanofluids	7
Photocatalytic Hydrogen Production Using TiO2‐based Catalysts: A Review	7
Toward Sustainable Composites: Graphene‐Modified Jute Fiber Composites with Bio‐Based Epoxy Resin	7
High‐Performance Isotropic Thermo‐Electrochemical Cells Using Agar‐Gelled Ferricyanide/Ferrocyanide/Guanidinium	6
Investigation of Highly Active Carbon‐, Cobalt‐, and Noble Metal‐Free MnO2/NiO/Ni‐Based Bifunctional Air Electrodes for Metal–Air Batteries with an Alkaline Electrolyte	6
Institutional Quality in Green and Digital Transition of EU Regions – A Recovery and Resilience Analysis	6
Future of Nanotechnology in Food Industry: Challenges in Processing, Packaging, and Food Safety	6
Masthead: (Global Challenges 7/2022)	6
Evaluation of Groundwater Potential Zones Using GIS‐Based Machine Learning Ensemble Models in the Gidabo Watershed, Ethiopia	6
Harnessing the Power of Light: The Synergistic Effects of Crystalline Carbon Nitride and Ti3C2Tx MXene in Photocatalytic Hydrogen Production	6
Eco‐Friendly Mechanochemical Approach to Magnetic Graphene Oxide: A High‐Efficiency Sorbent for Environmental Pollutant Removal	6
Sustainable Production Insight Through LCA and LCC Analysis of Injection Overmolded Structural Electronics Manufactured through Roll‐to‐Roll Processes	5
The Shifting Cultivation Juggernaut: An Attribution Problem (Global Challenges 8/2022)	5
High Pressure Extraction as a Green Alternative to the Conventional Sunflower Oil (Helianthus annuus) Production Process – Extraction with Pressurized Ethanol in an Intermittent Process and wit	5
Adoption Dynamics of Organic Pesticides Among Cocoa Producers In Two Ecological Zones Of Ghana	5
A Soil Monitoring Law for Europe	5
Photoelectrocatalytic Hydrogen Generation: Current Advances in Materials and Operando Characterization	5
Sustainable Strategies for Converting Organic, Electronic, and Plastic Waste From Municipal Solid Waste Into Functional Materials (Global Challenges 4/2025)	5
Engineering Oxygen Vacancies in (FeCrCoMnZn)3O4‐δ High Entropy Spinel Oxides Through Altering Fabrication Atmosphere for High‐Performance Rechargeable Zinc‐Air Batteries	5
Nickel Oxide Decorated Halloysite Nanotubes as Sulfur Host Materials for Lithium–Sulfur Batteries	5
Opportunities and Challenges of Establishing a Regional Bio‐based Polylactic Acid Supply Chain	5
Negatively but Not Positively Charged Nanoceria Promoted Lateral Root Growth via Modulating the Distribution of Reactive Oxygen Species Rather than Auxin	5
Is Photocatalysis the Next Technology to Produce Green Hydrogen to Enable the Net Zero Emissions Goal?	5
Synthesis of N‐Doped Graphene Photo‐Catalyst for Photo‐Assisted Charging of Li‐Ion Oxygen Battery	5
The Piggy Solution: Harnessing Food Waste for Sustainable Hog Farming	5
Techno‐Economic and Lifecycle Analysis of Green Colloidal Silver: Moving toward Scale‐Up	4
MBenes: A Comprehensive Review of Synthesis Techniques and Energy Storage Capabilities	4

How Problems with Microplastics in Research and Application Can be Overcome: Lessons From the Experience of Plastics Stakeholders	4
P–N Heterojunction System Eu‐Doped ZnO@GO for Photocatalytic Water Splitting	4
Issue Information	4
Masthead: (Global Challenges 9/2023)	4
IoT‐Based Hand Hygiene Compliance Monitoring System and Validation of Its Effectiveness in Hospital Environments	4
Masthead: (Global Challenges 6/2022)	4
Performance Impact of Lead‐Free CsSn0.5Ge0.5I3 Based Perovskite Solar Cells with HTL‐Free Incorporation	4
Sustained Agricultural Spraying: From Leaf Wettability to Dynamic Droplet Impact Behavior	4
Correction to “New Insight into Mercury Removal from Fish Meat Using a Single‐Component Solution Containing Cysteine”	4
Formation Dynamics of Honeycomb‐Like Capsules and Sponge‐Like Biofilms in Micrococcus Reveal a Novel Heavy Metal Avoidance Strategy	4
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Amine‐Functionalized Activated Carbon Monoliths by 3D Printing for Direct Air Capture	4
Green Synthesized Silver Nanoparticles: A Potential Antibacterial Agent, Antioxidant, and Colorimetric Nanoprobe for the Detection of Hg2+ Ions	4
How Circular Can the Chemical Industry Sector Be(come)?	4
Ferrihydrite Supported on Steel Slags as Catalyst for the Hydrogenation of Nitroarenes: A Virtuous Cycle of Wastes	4
The Shifting Cultivation Juggernaut: An Attribution Problem	4
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(Global Challenges 2/2024)	4
Controllable Doping of Mn into Ni0.075‐xMnxAl0.025(OH)2(CO3)0.0125·yH2O for Efficient Adsorption of Fluoride Ions	4
Efficient Oxidative Polymerization of Hydroxytyrosol Using Horseradish Peroxidase Immobilized on a Magnetic Silica‐Coated Nanocatalyst	4
Comment on “Sexism in Academia is Bad for Science and a Waste of Public Funding”	4
Waste to Energy: Combustion, Performance, and Emission Characteristics of Waste Animal Fats/Diesel Blends Premixed with Various Alcohols as Port Fuels	4
Photocatalytic Degradation of Methylene Blue Dye using PANI‐CuFe2O4 Nano Composite	4
Recycling Thermoset Systems by Vitrimerization Using Solid‐State Shear Extrusion‐ A Feasibility Study	4
Biobased Random Copolymers From Furandicarboxylic Acid Isomers: Proof of Concept for an Integrated Biorefinery Approach Toward Outstanding Sustainable Food Packaging	4
Mineral Plastics and Gels from Multi‐Arm Ionomers	4
The Impact of China's Carbon Market on the Decarbonization of the Coal Power Industry: An Approach Considering Long‐Term Carbon Net Expenditures	4
Formal Anti‐Markovnikov Addition of Water to Olefins by Titanocene‐Catalyzed Epoxide Hydrosilylation: From Stoichiometric to Sustainable Catalytic Reactions	3
Country‐Specific Participation Patterns in Transnational Governance Initiatives on Sustainability: Preliminary Insights and Research Agenda	3
Masthead: (Global Challenges 8/2024)	3
(Global Challenges 3/2023)	3
Boosting Water Retention in Agriculture: Vine Biochar‐Doped Hydrogels' Swelling and Germination Effects	3
Toward Ecofriendly Piezoelectric Ceramics—Reduction of Energy and Environmental Footprint from Conceptualization to Deployment	3
A Forest‐Based Triboelectric Energy Harvester	3
Superhydrophilic Interconnected Biomass‐Based Absorbers Toward High‐Speed Evaporation for Solar Steam Generation	3
Understanding the Role of Controlled Environments for Producing Mycelium‐bound Composites: Advancing Circular Practices for Integrating Biotechnology into the Construction Industry	3
Systems‐Level Optimization of Hybrid Produced Water Treatment Systems for Sustainable Oil and Gas Production: A Review of Current Technologies	3
Progress, Key Issues, and Future Prospects for Li‐Ion Battery Recycling	3
The Effects of Bromine Additives on the Recyclability of Injection Molded Electronic Waste Polymers	3
Decarbonization at What Cost? Assessing the Agricultural Economic Impact of Mitigation Policy: Evidence From Net‐Zero Targets	3
Decadal Evolution of Atmospheric Sulfate and Nitrate and Its Potential Link to Energy Restructuring: A Case Study in Guangdong Province, China	3
Mitigating Global Challenges: Harnessing Green Synthesized Nanomaterials for Sustainable Crop Production Systems	3
Time‐Efficient, Accurate, and Experimentally Grounded Optical Modeling of Multiscale‐Textured Thin‐Film Solar Cells	3
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Promising Pharmacological Interventions for Posterior Capsule Opacification: A Review	3
Transforming the Water‐Energy Nexus in Gaza: A Systems Approach	3
Preserving Cultural Diversity in Rural Africa Using Renewable Energy	3
Extreme Temperature Events in Kazakhstan and Their Impacts on Public Health and Energy Demand	3
Land Use and Land Cover Change Detection Using the Random Forest Approach: The Case of The Upper Blue Nile River Basin, Ethiopia	3
Food Waste Governance Architectures in Europe: Actors, Steering Modes, and Harmonization Trends	3
Conditions for CaCO3 Biomineralization by Trichoderma Reesei with the Perspective of Developing Fungi‐Mediated Self‐Healing Concrete	3
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Updates on Hydrogen Value Chain: A Strategic Roadmap	2
Potential of Seaweeds to Mitigate Production of Greenhouse Gases during Production of Ruminant Proteins	2
Reusing Waste Coffee Grounds as Electrode Materials: Recent Advances and Future Opportunities (Global Challenges 1/2023)	2
The Escalating Threat of Heatwaves in Central Asia: Climate Change Impacts and Public Health Risks	2
Potential Waste‐to‐Wealth Strategy for Combining Medical Surgical Gloves‐Derived Pyrolysis Oil with Pentanol and Nanoparticles: Experimental Analysis on Engine Behaviors	2
Carbon Storage Tanker Lifetime Assessment	2
Immobilization of Bi2WO6 on Polymer Membranes for Photocatalytic Removal of Micropollutants from Water – A Stable and Visible Light Active Alternative	2
Imogolite Nanotubes and Their Permanently Polarized Bifunctional Surfaces for Photocatalytic Hydrogen Production	2
Masthead: (Global Challenges 1/2024)	2
Effect of Poling on Photocatalysis, Piezocatalysis, and Photo–Piezo Catalysis Performance of BaBi4Ti4O15 Ceramics	2
A Preliminary Assessment of Global CO2: Spatial Patterns, Temporal Trends, and Policy Implications	2
Photovoltaic Materials and Their Path toward Cleaner Energy	2
Advancing Economical and Environmentally Conscious Electrification: A Comprehensive Framework for Microgrid Design in Off‐Grid Regions	2
Crop Diversification for Ensuring Sustainable Agriculture, Risk Management and Food Security	2
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Rosemary‐Mediated Green Synthesis of ZnO Nanoparticles and their Integration into Hydrogel Matrices: Evaluating Effects on Wheat Growth and Antibacterial Properties	2
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Characterization of Heavy Metal Ions Removal from Water by Improved Cuttlebone Powder with Magnetic Fe3O4 Nanoparticle as a Bioadsorbent	2
Simultaneous Laser Reduction of Sn/Sb Salts and Graphene Formation as Innovative Anode Material for Li‐ and Na‐Ion Batteries	2
Recent Advances in the Fabrication of Structural Nanocellulose‐Loaded Functionalized Biochar‐Based Biopolymeric Nanocomposites for Industrial Wastewater Treatment by Continuous Adsorption With Modelin	2
How to Improve Sustainability in Fused Filament Fabrication (3D Printing) Research?	2
Synthesis, Characterization, and Photocatalytic Activity of Magnetically Separable Fe3O4@SiO2@ZnO–Ag Composite Photocatalyst	2
Curcumin's Protective Role in Heatstroke‐Induced Acute Liver Injury: Targeting Pyroptosis and Enhancing SIRT1 Expression	2
Advances in Porous Structure Design for Enhanced Piezoelectric and Triboelectric Nanogenerators: A Comprehensive Review	2
Synthesis and Evaluation of 3D Nitrogen Doped Reduced Graphene Oxide (3D N@rGO) Macrostructure for Boosted Solar Driven Interfacial Desalination of Saline Water	2
Safety Concerns for the Management of End‐of‐Life Lithium‐Ion Batteries	2
Issue Information	2
Esterified Lignin from Construction and Demolition Waste (CDW) as a Versatile Additive for Polylactic‐Acid (PLA) Composites—The Effect of Artificial Weathering on its Performance	2