OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Discovery is 43. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)

Article	Citations
Sulfated polysaccharides effectively inhibit SARS-CoV-2 in vitro	244
The differential immune responses to COVID-19 in peripheral and lung revealed by single-cell RNA sequencing	184
Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro	166
SARS-CoV-2 N protein antagonizes type I interferon signaling by suppressing phosphorylation and nuclear translocation of STAT1 and STAT2	163
The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes	156
Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility	155
SARS-CoV-2 cell tropism and multiorgan infection	147
Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2	134
Single-cell analysis of pancreatic ductal adenocarcinoma identifies a novel fibroblast subtype associated with poor prognosis but better immunotherapy response	117
Plasma membrane integrity in health and disease: significance and therapeutic potential	100
Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS-CoV-2 replication and accelerates the negative conversion of infected patients	100
Emerging functions of branched ubiquitin chains	98
Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 alveolar macrophages	93
Robust induction of B cell and T cell responses by a third dose of inactivated SARS-CoV-2 vaccine	93
Global immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression	92
Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss	87
Calcium channel blocker amlodipine besylate therapy is associated with reduced case fatality rate of COVID-19 patients with hypertension	81
Generation of human blastocyst-like structures from pluripotent stem cells	75
Dynamic O-GlcNAcylation coordinates ferritinophagy and mitophagy to activate ferroptosis	75
SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication	74
A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy	73
Atomic structure of human TOM core complex	72
CD36+ cancer-associated fibroblasts provide immunosuppressive microenvironment for hepatocellular carcinoma via secretion of macrophage migration inhibitory factor	68
Single-cell transcriptome and TCR profiling reveal activated and expanded T cell populations in Parkinson’s disease	66
SARS-CoV-2 nucleocapsid protein undergoes liquid–liquid phase separation into stress granules through its N-terminal intrinsically disordered region	66

Reduced sensitivity of SARS-CoV-2 Omicron variant to antibody neutralization elicited by booster vaccination	63
Comprehensive investigations revealed consistent pathophysiological alterations after vaccination with COVID-19 vaccines	62
KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge	61
Patient-derived SARS-CoV-2 mutations impact viral replication dynamics and infectivity in vitro and with clinical implications in vivo	60
Single-cell transcriptome atlas of lung adenocarcinoma featured with ground glass nodules	57
Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence	55
Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor	55
Antihypertensive drugs are associated with reduced fatal outcomes and improved clinical characteristics in elderly COVID-19 patients	54
Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo	53
Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies	52
A genome-wide association study for gut metagenome in Chinese adults illuminates complex diseases	50
In vivo chemical reprogramming of astrocytes into neurons	48
Dysregulated hematopoiesis in bone marrow marks severe COVID-19	48
Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement	48
SARS-CoV-2 infection in the mouse olfactory system	47
Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter	45
Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos	44
Genome-wide association study of COVID-19 severity among the Chinese population	44