OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Discovery is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro	175
The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes	164
Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility	159
SARS-CoV-2 cell tropism and multiorgan infection	154
Single-cell analysis of pancreatic ductal adenocarcinoma identifies a novel fibroblast subtype associated with poor prognosis but better immunotherapy response	127
Emerging functions of branched ubiquitin chains	109
Plasma membrane integrity in health and disease: significance and therapeutic potential	107
Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 alveolar macrophages	100
CD36+ cancer-associated fibroblasts provide immunosuppressive microenvironment for hepatocellular carcinoma via secretion of macrophage migration inhibitory factor	98
Global immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression	98
Robust induction of B cell and T cell responses by a third dose of inactivated SARS-CoV-2 vaccine	97
Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss	95
Dynamic O-GlcNAcylation coordinates ferritinophagy and mitophagy to activate ferroptosis	90
A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy	88
Calcium channel blocker amlodipine besylate therapy is associated with reduced case fatality rate of COVID-19 patients with hypertension	85
SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication	81
Generation of human blastocyst-like structures from pluripotent stem cells	76
Single-cell transcriptome and TCR profiling reveal activated and expanded T cell populations in Parkinson’s disease	72
KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge	68
SARS-CoV-2 nucleocapsid protein undergoes liquid–liquid phase separation into stress granules through its N-terminal intrinsically disordered region	67
Comprehensive investigations revealed consistent pathophysiological alterations after vaccination with COVID-19 vaccines	64
Reduced sensitivity of SARS-CoV-2 Omicron variant to antibody neutralization elicited by booster vaccination	64
Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor	63
Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies	62
Dysregulated hematopoiesis in bone marrow marks severe COVID-19	54

Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo	53
A genome-wide association study for gut metagenome in Chinese adults illuminates complex diseases	53
In vivo chemical reprogramming of astrocytes into neurons	52
SARS-CoV-2 infection in the mouse olfactory system	49
Single-cell multiomics analysis reveals regulatory programs in clear cell renal cell carcinoma	49
Characterization of respiratory microbial dysbiosis in hospitalized COVID-19 patients	47
Genome-wide association study of COVID-19 severity among the Chinese population	46
Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos	45
Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter	45
Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome	42
Pyroptosis of syncytia formed by fusion of SARS-CoV-2 spike and ACE2-expressing cells	42
Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture	40
Antenna arrangement and energy-transfer pathways of PSI–LHCI from the moss Physcomitrella patens	39
Identification of an intraocular microbiota	39