OOIR: Observatory of International Research

Papers

(The median citation count of Regenerative Biomaterials is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Recombinant humanized type III collagen improves ovarian function via ITGA2-mediated mitochondrial function restoration in granulosa cells and extracellular matrix remodeling	54
Engineering stem cell exosomes promotes the survival of multi-territory perforator flap in diabetes via regulating anti-inflammatory and angiogenesis	54
The cutting-edge advancements in biomaterials under the guidance of intelligence and bionics	52
Biofabrication of zinc-reinforced PLA scaffolds by FDM for bone tissue engineering	46
Black phosphorus-loaded mineralized UV-responsive chitosan hydrogel for enhanced osteogenesis and antibacterial activity	39
Strategic incorporation of metal ions in bone regenerative scaffolds: multifunctional platforms for advancing osteogenesis	36
A neurovascularized bone regeneration strategy for mandibular and alveolar bone defects based on elastin-like biomaterials	35
Engineered collagen XVII-loaded dissolving microneedle patch for promoting hair regrowth in androgenic alopecia	33
Coordination-based nanocomposite hydrogel promotes tissue regeneration under infection-compromised conditions	32
Chondroitin sulfate reinforces mitochondrial redox homeostasis to enable integrated intervertebral disc regeneration	31
Advances in osseointegration of biomimetic mineralized collagen and inorganic metal elements of natural bone for bone repair	28
Mitochondria-targeted nanotechnology in cardiovascular diseases: a review of recent advances	27
Recombinant human collagen type III microgel: an advanced injectable dermal filler for rejuvenating aging skin	25
A dual-functional injectable polysaccharide hydrogel incorporating oxygen-carrying nanoemulsion and VEGF for enhancing islet survival and glycemic control in diabetic mice	24
Recent advances in biomaterials for osteosarcoma treatment	23
Mesoporous bioactive glass–recombinant collagen III nanocomposite capsule promotes skin wound healing via adaptive immune modulation	23
Injectable cartilage microtissues based on 3D culture using porous gelatin microcarriers for cartilage defect treatment	22
Acellular nerve perineurium repairs peripheral nerve injuries in a rat model via ECM-mediated barrier and optimization of the regenerative microenvironment	19
A dual-functional PEG-tyrosine hydrogel with photothermal effect and antioxidant capacity for cancer therapy and tissue regeneration	19
The Sr-HA-loaded PLGA cage structure combines cells to construct a bone tissue repair unit	19
Advanced materials and devices strategies of mechanical stimulation for tissue regeneration	19
Engineering a cell wall-deficient protoplast-incorporated hydrogel for infected wound healing	18
A novel polyester–drug nanoconjugate with subtype selectivity for high efficacy against PSMA-positive prostate cancer	17
The use of concentrated growth factors in guiding bone regeneration after microsurgical endodontic surgery for periapical lesions	17
Advanced bone-targeted nanomaterials for the systemic treatment of osteoporosis	16

Betaine based organ preservation solution alleviates renal allograft I/R injury by protecting endothelial cells	16
Engineered hierarchical 3D scaffold promotes bone regeneration through enhanced mechanotransduction	14
Bioinspired and smart material systems for auricular cartilage engineering: toward microenvironment-responsive and self-regulating scaffolds	14
Combined therapeutic strategy based on blocking the deleterious effects of AGEs for accelerating diabetic wound healing	13
Correction to: Synergistic Chemo-/Photothermal-therapy Based on Supercritical Technology-assisted Chitosan-Indocyanine Green/Luteolin Nanocomposites for Skin Wound Healing	13
Functionalized magnetic hydrogel encapsulation of human dental follicle stem cells under a static magnetic field enhances multi-site bone regeneration	13
Navigating oxidative stress in oral bone regeneration: mechanisms and reactive oxygen species-regulating biomaterial strategies	12
Magnesium ion hydrogel enhances resistance to radiation-induced bone injury by modulating the bone immune microenvironment and promoting microvascularization	12
Hybrid hydrogel system integrating thermoresponsive microspheres and KGN-loaded nanofibers enables efficient cartilage matrix regeneration	12
Promoting cell proliferation and collagen production with ascorbic acid 2-phosphate-releasing poly(l-lactide-co-ε-caprolactone) membranes for treating pelvic organ prolapse	11
Comparative effects of platelets and plasma-derived mitochondria in early-phase Achilles tendon inflammation	10
TiO2 nanotubes regulate osteo-adipogenic balance through SREBP1 to determine the fate of bone marrow mesenchymal stem cells	10
Retraction of: Gelatin-biofermentative unsulfated glycosaminoglycans semi-interpenetrating hydrogels via microbial-transglutaminase crosslinking enhance osteogenic potential of dental pulp stem cells	9
LL-37—biofunctionalized titanium improves soft tissue seal surrounding the dental implant from the perspective of optimizing a race to the surface	9
Bioengineered nasal septum implant with 3D-printed silicone and chondrocyte-seeded fibrin hydrogel	9
Design of novel interlocked bi-layer NiTi braided stent with ultra-thin walls for urinary tract obstruction treatment	9
Photothermal and cascade ROS generative multilayer as intraocular lens surface coating for effective posterior capsular opacification inhibition	8
Iron–quercetin nanocomplex preconditioning reprograms the mesenchymal stem cell secretome to drive angiogenic, fibroblast and immunoregulatory wound repair	8
Tetrahedral framework nucleic acids enhance the chondrogenic potential of human umbilical cord mesenchymal stem cells via the PI3K/AKT axis	8
Targeting delayed healing tissues: immune reprogramming of adaptive immune cells by biomaterials	7
Protein conformational transition microenvironment in silk fibroin hydrogels: proliferation and chondrogenesis of encapsulated stem cells	7
L-arginine-loaded microneedle patch enhances diabetic wound healing by regulating macrophage polarisation and mitochondrial homeostasis	7
Three-dimensionally-printed biphasic PCL/ β -TCP scaffold with spatially confined GelMA/CS hydrogel for coordinated osteochondral regeneration	7
Heterogeneous zinc/catechol-derived resin microsphere-functionalized composite hydrogels with antibacterial and anti-inflammatory activities promote bacterial-infected wound healing	7
Electrospinning based biomaterials for biomimetic fabrication, bioactive protein delivery and wound regenerative repair	6
Recombinant collagen for the repair of skin wounds and photo-aging damage	6
Hyaluronic acid methacrylate/laponite hydrogel loaded with BMP4 and maintaining its bioactivity for scar-free wound healing	6
Matrix metalloproteinase-2 and pH-responsive drug eluting multilayer as intraocular lens coating to improve the posterior capsule opacification inhibition	6
Synergistic integration of biomaterials in orthopedic implantation for infection preventing and tissue engineering	6
ROS-scavenging lipoic acid-modified chitosan hydrogels with rapid photocrosslinked ability accelerates peripheral nerve regeneration	6
A novel inherent fluorescence biodegradable polyurethane	6
Pathology-guided design of injectable hydrogels for precision therapy and cartilage regeneration in osteoarthritis	5
Ginseng-derived exosomes loaded in fibrin gel promote retinal ganglion cell survival in glaucoma by exerting anti-inflammatory effects through modulating microglial polarization	5
Magnetic chitosan nanoparticle-exosome hydrogel enhances bladder function in diabetic bladder dysfunction via activating the FAK-p38 MAPK-GATA4 axis in adipose-derived mesenchymal stromal cells	5
Corilagin functionalized decellularized extracellular matrix as artificial blood vessels with improved endothelialization and anti-inflammation by reactive oxygen species scavenging	5
Three-dimensional-printed strontium-incorporated β-TCP bioceramic triply periodic minimal surface scaffolds with enhanced angiogenic and osteogenic properties	5
Ascorbic acid 2-phosphate-releasing poly-l-lactide-co-epsilon-caprolactone membranes enhance tissue regeneration: first in vivo insights for pelvic organ	5
A ‘frost formation’-inspired near-infrared-responsive nitric oxide-releasing hydrogel for enhancing fat graft survival	5
A review on thermoresponsive PNIPAM hydrogels for regenerative medicine: from mechanical design to tissue adhesion	5
Plasma-derived mitochondria as a minimal manipulation alternative for attenuating inflammatory immune responses	4
Biomimetic lung-targeting vehicle coupled with cryo-shocked leukocyte and inflammation-anchored liposome for drug delivery and anti-inflammation in treatment of acute pneumonia	4
Plant-derived extracellular vesicles for drug delivery: current and future	4
Zonally patterned demineralized bone matrix–meniscus ECM composite scaffold directing region-specific fibrochondrogenic and angiogenic responses	4
Homologous-adhering/targeting cell membrane- and cell-mediated delivery systems: a cancer-catch-cancer strategy in cancer therapy	3
Bone-targeted lipoplex-loaded three-dimensional bioprinting bilayer scaffold enhanced bone regeneration	3
Refining the biomanufacturing of microalgae-derived extracellular vesicles as a potential nanotherapeutic for osteoarthritis	3
Low-intensity pulsed ultrasound stimulated hydrogel-polylactic acid composite scaffolds: a dual-cue approach for enhanced rotator cuff healing	3
3D printing materials and 3D printed surgical devices in oral and maxillofacial surgery: design, workflow and effectiveness	3
Cell membrane-coated nanoparticles against non-alcoholic fatty liver disease via regulating endoplasmic reticulum stress	3
Three-dimensional-printed triply periodic minimal surface scaffolds via digital light processing for enhanced osteogenesis	3

Comparative regenerative mechanisms of adipose-derived mesenchymal stem cell- and conditioned medium-loaded three-dimensional bioprinted hydrogels in chronic diabetic wounds	3
Ultrasound-activated UiO-66 enables ROS-mediated antibacterial therapy and accelerates diabetic wound healing	3
Integrating graph convolutional networks with large language models for structured biomedical material knowledge representation	3
Fabrication of an NIR-II fluorescence-visible indocyanine green-BioGlue for precision surgical adhesion with intraoperative leakage prevention	3
Synergistic self-assembly and crosslinking yield a durable, bioactive, and injectable recombinant collagen implant for photoaging therapy	2
Protection mechanism investigation of a protective coating on magnesium alloy stents via deformation model construction and the simulation of cellular automata	2
Stabilization of CXCL12 (SDF-1α) via silk fibroin films enhances stem cell migration/retention and functional recovery after stroke	2
ROS-triggered hydrophilicity switching synergizes with pH-responsive nanocarriers for therapy of diabetic wound	2
Biomimetic bilayer hydrogel coating with antithrombotic and anticalcification properties for cardiovascular tissue engineering application	2
Mussel inspired 3D elastomer enabled rapid calvarial bone regeneration through recruiting more osteoprogenitors from the dura mater	2
Advances in hydrogel-mediated gene therapy in ophthalmology: future directions and therapeutic potential	2
Biomimetic bone-vessel interface-on-a-chip for simulating periodontal physiological and pathological microenvironment	2
Dual-peptide engineered macrophage membrane biomimetic nanosystem via targeting Rg1 delivery for traumatic brain injury therapy	2
The 3D printed biphasic scaffolds incorporating epimedin C promotes osteochondral regeneration in osteoarthritis rats	2
A conductive MXene hydrogel reprograms immunity and autophagy to restore neurovascular repair in infected wounds	2
ROS scavenging Mn3O4 nanozyme regulated immune microenvironment and affects intercellular interaction to promote wound healing in diabetes	2
Rutin-encapsulated manganese carbonate nanoparticles for ‘liver-dark/tumor-bright’ magnetic resonance imaging and inhibition of breast cancer with liver metastases	2
Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation	2
Effects of molecular weight, end group of polylactide and coating thickness on corrosion rate and inhomogeneity of iron under biomimetic conditions	2
The utilization of chitosan/Bletilla striata hydrogels to elevate anti-adhesion, anti-inflammatory and pro-angiogenesis properties of polypropylene mesh in abdominal wall repair	1
A microgel-stabilized, light-controlled artificial energy supply module for efficient biosynthesis	1
Macrophage exosomes modified by miR-365-2-5p promoted osteoblast osteogenic differentiation by targeting OLFML1	1
Advanced lyophilized mesenchymal stem cell-conditioned medium formulation improves therapeutic efficacy in skin wound repair	1
Stimuli-responsive hydrogels for radiation-induced skin injury: from passive barriers to autonomous drug delivery systems	1
Three-dimensional bioprinted organoids: advances and clinical translation	1
Retraction of: Material and regenerative properties of an osteon-mimetic cortical bone-like scaffold	1
M1 macrophage-targeted engineered ginseng stems and leaves-derived extracellular vesicles delivery system for alleviating rheumatoid arthritis	1
Regulation of nerve cells using conductive nanofibrous scaffolds for controlled release of Lycium barbarum polysaccharides and nerve growth factor	1
Establishment of coverage-mass equation to quantify the corrosion inhomogeneity and examination of medium effects on iron corrosion	1
Physical decellularization of fish skin utilizing electrical fields	1
Sequential polarization of macrophages: an immunomodulatory strategy for novel bone repair materials	1
A smart nanocomposite bioactive ink for controlled siRNA delivery in calvarial mesenchymal stromal cells as a minimally invasive treatment for craniosynostosis	1
Tissue-engineered liver using 3D-printed silk fibroin scaffolds loaded with stem cells for the treatment of acute liver injury	1
Correction to: Material surface conjugated with fibroblast growth factor-2 for pluripotent stem cell culture and differentiation	1
Effect of a synthetic hydroxyapatite-based bone grafting material compared to established bone substitute materials on regeneration of critical-size bone defects in the ovine scapula	1
CaAm-P19: a novel amelogenin-derived peptide for enamel remineralization	1
Injectable platelet-rich plasma-based hydrogels: a controlled release platform for growth factors and cardiac regeneration post-myocardial infarction	1
Pitaya‑inspired compartmentalized microspheres with natural tannic acid-copper coating orchestrate smart release of ions and multi-drugs for synergistic treatment of infected bone defects	1
Regulation of calcium delivery and pore structure via osteoinductive microspheres of HA/CS/PGCL for orbital bone regeneration	1
Rhodiola rosea-derived exosome-like nanovesicles inhibit vascular endothelial pyroptosis in the treatment of limb skeletal muscle ischemic injury through the TXNIP/NLNP3 pathway	1
Cryostorable callus mimetics support endochondral bone regeneration in a large-animal maxillofacial defect	1
Manganese-doped nano-hydroxyapatite enhances CF/PEEK osseointegration via immunomodulation-osteogenesis coupling	1
ROS-responsive adhesive nanocomposite hydrogel promotes tendon-to-bone healing by modulating the inflammatory microenvironment and pro-differentiation	1
Influence of micro- and nanoscale cues on immune factors secretion: implications for immunomodulation	1
Quantitatively relating magnetic resonance T1 and T2 to glycosaminoglycan and collagen concentrations mediated by penetrated contrast agents and biomacromolecule-bound water	1
Decellularization of porcine dermis via supercritical CO2-assisted co-solvent system for cutaneous wound healing	1
Microporous structures on mineralized collagen mediate bone restoration by promoting nucleolin secretion to induce macrophage M2 polarization	1
Development and optimization of electrophoretically deposited octacalcium phosphate–collagen film as bone analogues	1