OOIR: Observatory of International Research

Papers

(The TQCC of Biomaterials Research is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Current aspects of small extracellular vesicles in pain process and relief	281
Bioactive Glasses: Advancing Skin Tissue Repair through Multifunctional Mechanisms and Innovations	96
Hierarchy Reproduction: Multiphasic Strategies for Tendon/Ligament–Bone Junction Repair	88
PEDF-Enriched Extracellular Vesicle for Vessel Normalization to Potentiate Immune Checkpoint Blockade Therapy	71
Evaluating the validity of lightweight talar replacement designs: rational models and topologically optimized models	70
Recent Advancements in Biomaterials for Chimeric Antigen Receptor T Cell Immunotherapy	69
Human nasal septal chondrocytes (NSCs) preconditioned on NSC-derived matrix improve their chondrogenic potential	66
Two-Dimensional “Nanotanks” Release “Gas Bombs” through Photodynamic Cascades to Promote Diabetic Wound Healing	58
Additively manufactured titanium scaffolds and osteointegration - meta-analyses and moderator-analyses of in vivo biomechanical testing	58
Nanotherapeutic System with Effective Microwave Sensitization and Pyroptosis Programming Enable Synergistic Microwave-Immunotherapy in Bladder Cancer	58
Combining Gut Microbiota Modulation and Enzymatic-Triggered Colonic Delivery by Prebiotic Nanoparticles Improves Mouse Colitis Therapy	53
De novo design of a novel AIE fluorescent probe tailored to autophagy visualization via pH manipulation	52
Stem cell laden nano and micro collagen/PLGA bimodal fibrous patches for myocardial regeneration	52
High-Frequency Optical Coherence Elastography for Gingival Tissue Characterization: Variability in Stiffness and Response to Physiological Conditions	51
Effect of bioactive glass addition on the physical properties of mineral trioxide aggregate	50
A functional neuron maturation device provides convenient application on microelectrode array for neural network measurement	50
Evaluation of Integrity of Allogeneic Bone Processed with High Hydrostatic Pressure: A Pilot Animal Study	49
Osteogenic effects of exosomes derived from human chorion membrane extracts	49
P800SO3-PEG: a renal clearable bone-targeted fluorophore for theranostic imaging	49
Confocal imaging of biomarkers at a single-cell resolution: quantifying 'living' in 3D-printable engineered living material based on Pluronic F-127 and yeast Saccharomyces cerevisiae	43
Enhanced Chondrogenic Differentiation of Electrically Primed Human Mesenchymal Stem Cells for the Regeneration of Osteochondral Defects	43
Erratum to “An Ultrasoft and Flexible PDMS-Based Balloon-Type Implantable Device for Controlled Drug Delivery”	41
The Biological Effects of Magnesium-Based Implants on the Skeleton and Their Clinical Implications in Orthopedic Trauma Surgery	40
Novel antibacterial and apatite forming restorative composite resin incorporated with hydrated calcium silicate	40
Antibacterial Immunonegative Coating with Biocompatible Materials on a Nanostructured Titanium Plate for Orthopedic Bone Fracture Surgery	39

A novel gelatin/chitooligosaccharide/demineralized bone matrix composite scaffold and periosteum-derived mesenchymal stem cells for bone tissue engineering	39
Microenvironment Remodeling Self-Healing Hydrogel for Promoting Flap Survival	37
Natural bone-mimicking nanopore-incorporated hydroxyapatite scaffolds for enhanced bone tissue regeneration	36
Biomaterial-Based CRISPR/Cas9 Delivery Systems for Tumor Treatment	36
Strategies to Overcome Hurdles in Cancer Immunotherapy	36
NIR-Triggered Release of Nitric Oxide by Upconversion-Based Nanoplatforms to Enhance Osteogenic Differentiation of Mesenchymal Stem Cells for Osteoporosis Therapy	35
Polydopamine-Cloaked Nanoarchitectonics of Prussian Blue Nanoparticles Promote Functional Recovery in Neonatal and Adult Ischemic Stroke Models	35
Coacervate-mediated novel pancreatic cancer drug Aleuria Aurantia lectin delivery for augmented anticancer therapy	34
Pulmonary Delivery of Anti-microRNA Oligonucleotide and Glycyrrhizic Acid Using Ternary Peptide Micelles for the Treatment of Acute Lung Injury	32
Cell Membrane-Coated Nanotherapeutics for the Targeted Treatment of Acute and Chronic Colitis	32
Recent advances in surface-mounted metal–organic framework thin film coatings for biomaterials and medical applications: a review	32
Manufacturing Uniform Cerebral Organoids for Neurological Disease Modeling and Drug Evaluation	31
A novel DNA double-strand breaks biosensor based on fluorescence resonance energy transfer	30
Navigating Latency-Inducing Viral Infections: Therapeutic Targeting and Nanoparticle Utilization	29
GelMA-based bioactive hydrogel scaffolds with multiple bone defect repair functions: therapeutic strategies and recent advances	28
Smart and versatile biomaterials for cutaneous wound healing	28
Injectable hydrogel nanoarchitectonics with near-infrared controlled drug delivery for in situ photothermal/endocrine synergistic endometriosis therapy	27
Shape-memory collagen scaffold combined with hyaluronic acid for repairing intervertebral disc	26
Stabilization and improved functionality of three-dimensional perfusable microvascular networks in microfluidic devices under macromolecular crowding	26
3D printed scaffolds based on hyaluronic acid bioinks for tissue engineering: a review	25
Nanotherapeutics with immunoregulatory functions for the treatment of bacterial infection	25
Enhancing Cancer Therapy: Boron-Rich Polyboronate Ester Micelles for Synergistic Boron Neutron Capture Therapy and PD-1/PD-L1 Checkpoint Blockade	24
Biomaterial-based cell delivery strategies to promote liver regeneration	24
Emerging 3D bioprinting applications in plastic surgery	24
Molecularly imprinted polymers (MIPs): emerging biomaterials for cancer theragnostic applications	24
High yield engineered nanovesicles from ADSC with enriched miR-21-5p promote angiogenesis in adipose tissue regeneration	24
Engineered exosomes enriched in netrin-1 modRNA promote axonal growth in spinal cord injury by attenuating inflammation and pyroptosis	24
Progress of tissue adhesives based on proteins and synthetic polymers	23
Clinical efficacy of amniotic membrane with biphasic calcium phosphate in guided tissue regeneration of intrabony defects- a randomized controlled clinical trial	23
Modularized bioceramic scaffold/hydrogel membrane hierarchical architecture beneficial for periodontal tissue regeneration in dogs	23
Aspirin in the Form of Microneedle Repairs DNA and Reduces Inflammation in Persistent Skin Damage	23
Self-curling 3D oriented scaffolds from fish scales for skeletal muscle regeneration	22
Functional insights from targeted imaging BACE1: the first near-infrared fluorescent probe for Alzheimer’s disease diagnosis	22
Bionic natural small molecule co-assemblies towards targeted and synergistic Chemo/PDT/CDT	22
Construction of antibacterial nano-silver embedded bioactive hydrogel to repair infectious skin defects	22
A novel and cost-effective method for high-throughput 3D culturing and rhythmic assessment of hiPSC-derived cardiomyocytes using retroreflective Janus microparticles	21
Emerging biomaterials for tumor immunotherapy	21
Immune cell targeting nanoparticles: a review	21
CRISPR/Cas9 assisted stem cell therapy in Parkinson's disease	20
Construction of magnetic nanochains to achieve magnetic energy coupling in scaffold	20
Recent advances in transdermal drug delivery systems: a review	20
Research Progress on Extracellular Matrix-Based Composite Materials in Antibacterial Field	19
Harnessing Nanotechnology for Gout Therapy: Colchicine-Loaded Nanoparticles Regulate Macrophage Polarization and Reduce Inflammation	19
An injectable, in situ forming and NIR-responsive hydrogel persistently reshaping tumor microenvironment for efficient melanoma therapy	19
Ultrasonic-controlled drug release prevents pro-tumorigenic transition and improves sequential targeting effect to enhance treatment of residual HCC	18
Size-Dependent Effect of Indocyanine Green Nanoimaging Agent for Metastatic Lymph Node Detection	18
MXene-derived Multifunctional Biomaterials: New Opportunities for Wound Healing	18
A methylprednisolone-loaded and core-shell nanofiber-covered stent-graft to prevent inflammation and reduce degradation in aortic dissection	17
Multifunctional hydrogels: advanced therapeutic tools for osteochondral regeneration	17
Albumin-binding photosensitizer capable of targeting glioma via the SPARC pathway	17

Evaluation of cellular response and drug delivery efficacy of nanoporous stainless steel material	17
Beyond canonical PROTAC: biological targeted protein degradation (bioTPD)	17
Novel Estrogen Receptor Dimerization BRET-Based Biosensors for Screening Estrogenic Endocrine-Disrupting Chemicals	17
Combinatorial nanococktails via self-assembling lipid prodrugs for synergistically overcoming drug resistance and effective cancer therapy	16
Moringa oleifera gum based silver and zinc oxide nanoparticles: green synthesis, characterization and their antibacterial potential against MRSA	16
Fabrication of a three-dimensional bone marrow niche-like acute myeloid Leukemia disease model by an automated and controlled process using a robotic multicellular bioprinting system	16
si-Tgfbr1-loading liposomes inhibit shoulder capsule fibrosis via mimicking the protective function of exosomes from patients with adhesive capsulitis	16
High-Throughput Screening of 3-Dimensional Co-culture Hair Follicle Mimetic Tissue with an Enhanced Extracellular Matrix for the Screening of Hair Growth-Promoting Compounds	15
Polydopamine (PDA) coatings with endothelial vascular growth factor (VEGF) immobilization inhibiting neointimal formation post zinc (zn) wire implantation in rat aortas	15
Recent biomedical advancements in graphene oxide- and reduced graphene oxide-based nanocomposite nanocarriers	15
GM-CSF augmented the photothermal immunotherapeutic outcome of self-driving gold nanoparticles against a mouse CT-26 colon tumor model	15
The role of cellular traction forces in deciphering nuclear mechanics	15
Improved Neural Inductivity of Size-Controlled 3D Human Embryonic Stem Cells Using Magnetic Nanoparticles	14
Genetically Modified Hepatocytes Targeting Bilirubin and Ammonia Metabolism for the Construction of Bioartificial Liver System	14
Axon guidance gene-targeted siRNA delivery system improves neural stem cell transplantation therapy after spinal cord injury	14
Liposomes targeting the cancer cell-exposed receptor, claudin-4, for pancreatic cancer chemotherapy	14
Biomimetic hydrogel blanket for conserving and recovering intrinsic cell properties	14
Injectable and Near-Infrared Light-Controllable Fibrin Hydrogels with Antimicrobial and Immunomodulating Properties for Infected Wound Healing	14
Human mini-blood–brain barrier models for biomedical neuroscience research: a review	14
Pericytes Enrich the Basement Membrane and Reduce Neutrophil Transmigration in an In Vitro Model of Peripheral Inflammation at the Blood–Brain Barrier	14
Nanoarchitectured conjugates targeting angiogenesis: investigating heparin-taurocholate acid conjugates (LHT7) as an advanced anti-angiogenic therapy for brain tumor treatment	14
Advances in surface modifications of the silicone breast implant and impact on its biocompatibility and biointegration	14
Improvement of Charcot-Marie-Tooth Phenotype with a Nanocomplex Treatment in Two Transgenic Models of CMT1A	13
Cellular direct conversion by cell penetrable OCT4-30Kc19 protein and BMP4 growth factor	13
Erratum to “Ultrasound Controllable Release of Proteolysis Targeting Chimeras for Triple-Negative Breast Cancer Treatment”	13
A Novel Lipopeptide–Functionalized Metal–Organic Framework for Periodontitis Therapy through the Htra1/FAK/YAP Pathway	13
Effect of sequential electrospinning and co-electrospinning on morphological and fluid mechanical wall properties of polycaprolactone and bovine gelatin scaffolds, for potential use in small diameter	13
3D biofabrication of diseased human skin models in vitro	12
Metallic Copper-Based Dual-Enzyme Biomimetic Nanoplatform for Mild Photothermal Enhancement of Anticancer Catalytic Activity	12
Plasma polymerized bio-interface directs fibronectin adsorption and functionalization to enhance “epithelial barrier structure” formation via FN-ITG β1-FAK-mTOR signaling cascade	12
CD62E- and ROS-Responsive ETS Improves Cartilage Repair by Inhibiting Endothelial Cell Activation through OPA1-Mediated Mitochondrial Homeostasis	12
Thermosensitive Polyhedral Oligomeric Silsesquioxane Hybrid Hydrogel Enhances the Antibacterial Efficiency of Erythromycin in Bacterial Keratitis	12
Optimized Epigallocatechin Gallate Delivery and Adipogenesis Inhibition through Fluorescent Mesoporous Nanocarriers	12
Hyaluronate/black phosphorus complexes as a copper chelating agent for Wilson disease treatment	12
Sequential activation of M1 and M2 phenotypes in macrophages by Mg degradation from Ti-Mg alloy for enhanced osteogenesis	12