OOIR: Observatory of International Research

Papers

(The H4-Index of Biomaterials Research is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
The Strontium Ion Reprograms Monocyte Subsets via TRPM2 Channel Regulation to Enhance Osseointegration	280
Erratum to “An Ultrasoft and Flexible PDMS-Based Balloon-Type Implantable Device for Controlled Drug Delivery”	212
Construction of a Bioactive ECM Interface Enables Concurrent Suppression of Foreign Body Reaction, Inflammation, and Promotion of Urethral Regeneration	157
A Peptide Inhibitor of Lymphocyte Activation Gene-3 Interaction with Fibrinogen-like Protein 1 Synergizes with Programmed Death-Ligand 1 Blockade to Restore T Cell Activity and Inhibit Tumor Growth	134
Label-Free Prediction of Fluorescently Labeled Fibrin Networks	130
Strategies to Overcome Hurdles in Cancer Immunotherapy	106
Tumoricidal Efficacy of Artesunate-Eluting Microsphere: Differential Role of Bax/Bak in Orchestration of Cell Death Pathways	105
Bioactive Glasses: Advancing Skin Tissue Repair through Multifunctional Mechanisms and Innovations	103
Prominent Alveolar Bone Graft Substitute Derived from Silk Fibroin/Hyaluronic Acid/Demineralized Dentin Matrix Hybrid Hydrogel	98
Stem cell laden nano and micro collagen/PLGA bimodal fibrous patches for myocardial regeneration	98
Zein and Trimethyl Chitosan-Based Core–Shell Nanoparticles for Quercetin Oral Delivery to Enhance Absorption by Paracellular Pathway in Obesity Mice	96
Targeting Reactive Oxygen Species and Inflammation in Sepsis-Induced Liver Injury with Naturally Derived Superoxide Dismutase-Mimicking Carbon Dots	92
Enhanced Chondrogenic Differentiation of Electrically Primed Human Mesenchymal Stem Cells for the Regeneration of Osteochondral Defects	89
An injectable, in situ forming and NIR-responsive hydrogel persistently reshaping tumor microenvironment for efficient melanoma therapy	83
Focused Ultrasound-Triggered Burst Release and Enrichment of Engineered Bacteria for Tumor Therapy	82
Enhanced Cellular Immunity for Hepatitis B Virus Vaccine: A Novel Polyinosinic-Polycytidylic Acid-Incorporated Adjuvant Leveraging Cytoplasmic Retinoic Acid-Inducible Gene-Like Receptor Activation and	78
Improved Neural Inductivity of Size-Controlled 3D Human Embryonic Stem Cells Using Magnetic Nanoparticles	76
Optimized Epigallocatechin Gallate Delivery and Adipogenesis Inhibition through Fluorescent Mesoporous Nanocarriers	75
Targeting treatment of bladder cancer using PTK7 aptamer-gemcitabine conjugate	70
Axon guidance gene-targeted siRNA delivery system improves neural stem cell transplantation therapy after spinal cord injury	70
Genetically Modified Hepatocytes Targeting Bilirubin and Ammonia Metabolism for the Construction of Bioartificial Liver System	69
Drug-loaded microbubble delivery system to enhance PD-L1 blockade immunotherapy with remodeling immune microenvironment	69
Light-Curable Methacrylated Carboxymethyl Chitosan Hydrogel Incorporating Bone Morphogenic Protein-2-Immobilized Bioactive Glass for Spinal Bone Regeneration	64
Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Oxidative Damage via the miR-191-5p/DAPK1/AKT Axis in Type 2 Diabetes	63
High-Throughput Screening of 3-Dimensional Co-culture Hair Follicle Mimetic Tissue with an Enhanced Extracellular Matrix for the Screening of Hair Growth-Promoting Compounds	60

Fabrication of a three-dimensional bone marrow niche-like acute myeloid Leukemia disease model by an automated and controlled process using a robotic multicellular bioprinting system	59
Size-Dependent Effect of Indocyanine Green Nanoimaging Agent for Metastatic Lymph Node Detection	59
A Novel Lipopeptide–Functionalized Metal–Organic Framework for Periodontitis Therapy through the Htra1/FAK/YAP Pathway	55
Radiation-Activated Cobalt-Based Zeolite Imidazolate Frameworks for Tumor Multitherapy	54
A New Perspective on Precision Medicine: The Power of Digital Organoids	54
Harnessing the Intradermal Delivery of Hair Follicle Dermal Papilla Cell Spheroids for Hair Follicle Regeneration in Nude Mice	54
Simultaneously Modulating HIF-1α and HIF-2α and Optimizing Macrophage Polarization through the Biomimetic Gene Vector toward the Treatment of Osteoarthritis	54
Customized Sized Manganese Sulfide Nanospheres as Efficient T ₁ MRI Contrast Agents for Enhanced Tumor Theranostics	53
An Ultrasoft and Flexible PDMS-Based Balloon-Type Implantable Device for Controlled Drug Delivery	49
Genetically Encoded Fluorescence Resonance Energy Transfer Biosensor for Live-Cell Visualization of Lamin A Phosphorylation at Serine 22	49
Modulation of bioactive calcium phosphate micro/nanoparticle size and shape during in situ synthesis of photo-crosslinkable gelatin methacryloyl based nanocomposite hydrogels for 3D bioprinting and ti	48
Engineering Glioma-Cell-Derived Exosomes as Trojan Horse for Precisely Targeted Chemotherapy of Glioblastoma	48
Polymer composite microspheres loading ¹⁷⁷ Lu radionuclide for interventional radioembolization therapy and real-time SPECT imaging of hepatic cancer	47
Advances in the development of tubular structures using extrusion-based 3D cell-printing technology for vascular tissue regenerative applications	47
Three-Dimensional Cultured Human Dermal Papilla Cells in HGC-Coated Environments Enhance Hair Regeneration and Artificial Skin Integration	46
Verapamil-loaded supramolecular hydrogel patch attenuates metabolic dysfunction-associated fatty liver disease via restoration of autophagic clearance of aggregated proteins and inhibition of NLRP3	46
Control of maleic acid-propylene diepoxide hydrogel for 3D printing application for flexible tissue engineering scaffold with high resolution by end capping and graft polymerization	46
Dual-Channel NIR Fluorescence Imaging for Precise Delineation of Gastric Tumor Margins	46
Paris polyphylla var. yunnanensis Leaf-Derived Extracellular Vesicle-Like Particles Enhance Periodontal Regeneration	45
mRNA nanodelivery systems: targeting strategies and administration routes	45
Enhanced Postsurgical Cancer Treatment Using Methacrylated Glycol Chitosan Hydrogel for Sustained DNA/Doxorubicin Delivery and Immunotherapy	45
Biomimetic Layered Double Hydroxide-Molybdenum Disulfide Encapsulated with Bovine Serum Albumin: A Multifaceted Nanotherapy for Inflammatory Bowel Disease	45
The worldwide patent landscape of dental implant technology	45