OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Virus Eradication is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
PP 1.33 – 00167 Integrated single-cell multi-omic profiling of HIV latency reversal	47
PP 3.8 – 00137 Characterization of the HIV-1 subtype C reservoir during ART in South-African men and women	35
OP 1.6 – 00138 Role of UHRF1 in HIV-1 transcriptional repression through epigenetic and non-epigenetic mechanisms	16
8.2 – 00072 Early intervention with an indoline CD4-mimetic compound that sensitizes HIV-1-infected cells to ADCC favors post-treatment HIV control in humanized mice	14
OP 5.2 – 00070 Characterization of a dual PTPN1/PTPN2 inhibitor to target latent HIV reservoirs	14
PP6.5 – 00086 Regulation of AAV transgene expression using nanoparticledelivered Cre-recombinase	14
Factors associated with unquantifiable total HIV-1 DNA in peripheral blood in persons living with HIV: An observational study	12
PP1.19 – 00036 Unexpected Redundancy of the TNF/NF-kB Axis in HIV-1 Restriction and Latency Reversal in Primary Human MDM Polarized to M1 Cells	12
2-Deoxyglucose as a therapeutic strategy for EBV-associated gastric carcinoma: Glycolytic and lytic reactivation inhibition under hypoxic conditions	11
Editorial JVE 10.2	11
Dynamic changes in immune cell subsets in blood and lymph node over the course of acute HIV infection	11
5.5 – 00117 HIV-Tocky system in primary CD4+T cells joined with transcriptomic and epigenomic analysis to discover mechanism involves in the establishment of latency during acute infection	10
PP1.16 – 00059 Identification of solo-LTR HIV provirus in vitro	10
ST2.4 – 00035 Bach controls seeding of HIV reservoirs in memory CD4+ T cells	10
OP 3.1 HIV Persistence in women, an update	7
PP5.11 – 00071 A novel in vitro model for studying HIV infection and latency in microglia: SIV Vpx-treated EcoHIV-infected CHME5	7
PP 7.8 – 00060 Slowing or Reversal of Decay of Intact Proviruses Over Two Decades of Suppressive ART	6
OP 1.2 – 00157 HIV Silencing and Cell Survival Signatures of HIV-Infected CD4 T Cell Transcriptomes under Antiretroviral Therapy (ART)	6
Langya virus outbreak in China, 2022: Are we on the verge of a new pandemic?	6
PP 2.1 – 00014 Impact of early antiretroviral therapy on tissue resident myeloid cells in the liver and lung of SIV-infected rhesus macaques	6
Origin, distribution and incidence of human rabies in Côte d’Ivoire from 2013 to 2023	6
Highlights of HIV Cure in IAS, Montréal	6
PP7.1-00174 Active HIV reservoir in jejunum exhibit distinct phenotypic features and evoke innate cell redistribution	5
OP 4.3 – 00112 Leaky reservoirs are associated with HIV-specific cd4 and CD8 T-cell responses	5
OP 1.4 – 00053 Definitive evidence of a persistent HIV reservoir in human brain myeloid cells despite ART	5

PP2.5 – 00122 The role of Vpr in the epigenetic regulation of HIV-1 latency	5
8.4 – 00081 IL-15/IL-15RA Therapy Enhances Control of Viral Rebound in SIVInfected Macaques	5
Combining treatment for chronic hepatitis C with opioid agonist therapy is an effective microelimination strategy for people who inject drugs with high risk of non-adherence to direct-acting antiviral	5
Substantial uneven proliferation of CD4+ T cells during recovery from acute HIV infection is sufficient to explain the observed expanded clones in the HIV reservoir	5
PP6.7 – 00070 Blockade of HIV-1 Latency Reversal in CD4+ T Cells from ARTsuppressed PLWH by the HIV-1 Antisense Transcript AST	5
The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture	5
PP 6.5 – 00205 Utilization of high-throughput assays and deep-learning for selection of CRISPR/Cas9-gRNA pairs used in an HIV-1 cure strategy	5
OP 3.8 – 00066 Characterization of the HIV-1 viral reservoir in subtype B early treated individuals	5
Impact of hepatitis B vaccination programs in Vietnam evaluated by estimating HBsAg prevalence	5
PP5.3 – 00166 Treatment with AZD5582 + het-IL15 transiently disrupts the reservoir establishment in SIV-infected macaques	5
PP 1.26 – 00143 Understanding HIV transcription in Kaposi's sarcoma tumors during antiretroviral therapy	4
OP 3.6 – 00023 Effect of HIV-1 infection, viral particle production, and proviral integration site on CD4+ T cell proliferation	4
OP 4.8 – 00149 CD8+ T cells promote hiv latency in CD4+ T cells through the downmodulation of NF-kB	4
PP 1.27 – 00147 Role of the pol gene enhancer in HIV-1 transcription and replication in myeloid infected cells	4
Editorial 10.4	3
Design and analysis considerations for early phase clinical trials in hepatitis B (HBV) cure research: the ACTG A5394 study in persons with both HIV and HBV	3
PP 3.20 – 00154 Epigenetic modifying compounds negatively impact viral replication within primary human macrophages	3
PP 3.14 – 00190 Ex vivo response to latency reversal agents of CD4+ T cell subsets and monocyte derived HIV-1 subtype C LTR from individuals on suppressive cART	3
PP3.3 – 00121 Exploring the Effects of Benzodiazepines on a Novel Mechanism of Control in HIV-1 Infected Human Monocyte Derived Macrophages	3
PP 1.35 – 00172 A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV infected cells	3
PP4.6 – 00115 Disruption of intestinal germinal centers during HIV infection	3
Relatively high interest but limited active engagement in HIV cure research: Awareness, interest, and information-seeking among affected communities in the Netherlands	3
PP 1.11 – 00075 Selective nuclear retention of spliced and unspliced HIV-1 mRNAs following latency reversal	3
PP3.4 – 00100 Retinoids enhance NK effector functions against HIV infected CD4 T cells	3
PP4.16 – 00014 Reduction of HIV-1 reservoir following mpox infection	3
PP2.3 – 00168 Blocks to HIV transcriptional initiation, elongation, and splicing contribute differentially to inefficient virus reactivation across authentic reservoir-harboring CD4+ T-cell clones	3
Editorial Board	3
Heat shock protein: a double-edged sword linking innate immunity and hepatitis B virus infection	3
PP7.2 – 00169 Longitudinal Persistence of HIV DNA in CSF Over 4 Years Despite Up to 20 Years of ART	3
1.6 – 00161 HIV-1 Antisense Transcripts are frequent in FOXP3-negative Treglike cells expressing markers of persistence in vivo during acute HIV- 1 infection	3
PP 1.34 – 00170 Intestinal endothelial cells substantially increase HIV infection and latency in resting and activated CD4+ T cells, particularly affecting CCR6+ Th17 subpopulation	2
To prescreen or not to prescreen for broadly neutralizing antibody sensitivity in HIV cure-related trials	2
Assessment of the general population knowledge about the emergence of Nipah virus outbreak in Bangladesh: A nationwide cross-sectional study	2
PP7.3 – 00149 Ultra-sensitive secondary structure RNA quantification in the HIV Reservoir Assay Validation and Evaluation Network (RAVEN) using the BioSnap assay	2
PP5.5 – 00152 IL-15, Type I interferon, and amino acid pathways are correlated with SIV reservoir size and magnitude of viral rebound post-ATI in SIV-infected infant rhesus macaques	2
OP 2.5 – 00048 Targeting the SIV reservoir with Alemtuzumab	2
PP 7.2 – 00006 Acceptability of Home-Based Blood Collection Device for Viral Load Testing in HIV Cure Trials with Analytical Treatment Interruptions	2
Bypassing primary antiretroviral therapy centres in Sub-Saharan Africa: An integrative review of the theoretical and empirical literature	2
The impact of acute stress on the HIV reservoir: a prospective interventional trial	2
PP3.1 – 00160 Macrophage Training Reactivates Latent HIV-1 from HAARTsuppressed PBMCs of PLWH	2
PP 4.27 – 00202 Single-cell RNA sequencing reveals CBD genetic signature in monocyte gene expression	2
OP 2.2 – 00200 Characterization of the SIV tissue reservoir transcriptional environment at the single focus level during ART and post ATI	2
PP 4.21 – 00050 Seeding of long-lived HIV cellular reservoirs through differentiation of infected CCR5+CD4+ T cells into central memory cells	2
PP 4.10 – 00119 Multiomic dynamics of the cellular HIV reservoir after rebound during ATI	2
OP 2.8 – 00193 Enhancing PKC Modulator HIV Latency Reversing Agents	2
Evolution of split-protein technologies in virology: From mechanistic discovery and diagnostics to therapeutic promise	2
PP6.8 – 00062 Evaluating the Combination Effect of Autophagy Induction and CAR T Cell Therapy on “Kick-and-Kill” HIV Reservoir Depletion	2
PP2.4 – 00157 Development of a Virology Quality Assurance Program to Assess Inter-lab Reproducibility of HIV-1 Reservoir Assays	2
PP4.8 – 00099 Activation of Immune Effector Responses in Newborns with Perinatal HIV infection	1
2.1 – 00040 Lenacapavir impairs gag proteins expression by HIV-infected cells	1

OP 1.1 Sequencing HIV: Significance and Impact	1
Vaccination against COVID-19 among healthcare workers as a cocoon strategy for people living with HIV	1
PP 2.11 – 00144 Transcriptional and translational SIV profiles of peripheral and lymphoid CD4+ T cells of viremic and ART-suppressed Rhesus macaques	1
PP4.9 – 00090 Changes in CPSF6 and SC35 expression and subcellular localization induced by dasatinib and ponatinib as mechanism to interfere with HIV-1 proviral integration in macrophages	1
OP 4.4 – 00018 HIV reservoir burden associates with numbers of HIV-specific CD8+ T cells under long-term antiretroviral therapy and prevents them from differentiating into functional memory cells	1
PP 4.11 – 00126 Autologous Neutralizing Antibodies Increase with Early Antiretroviral Therapy and Shape HIV Rebound after Treatment Interruption	1
PP5.10 – 00033 Ex vivo HIV DNA integration in STAT3 drives T cell persistence—A model of HIV-associated T cell lymphoma	1
PP 1.5 – 00040 Mapping of genetic interaction networks identifies a nucleosomal modification complex for silencing HIV	1
OP 6.3 – 00150 Delivery and long-term expression of CCR5-blocking monoclonal antibody Leronlimab with AAV for ART-free remission from SHIV viremia	1
HIV-1 latency: From acquaintance to confidant	1
PP 5.1 – 00045 Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Long-Acting Lenacapavir for Treatment of HIV	1
Navigating the HIV/AIDS epidemic in Bangladesh: A comprehensive retrospective analysis of epidemiological trends and sex-specific disparities (1990–2021) with long-term ARIMA forecasting to 2050 for s	1
PP2.2 – 00177 Late Increases in Intact Proviral DNA Reveal Variable HIV-1 Reservoir Dynamics	1
PP 1.2 – 00011 Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar zone supportive of early transcription reactivation	1
PP6.4 – 00096 Therapeutic efficacy of AAV-delivered HIV-1 bNAbs to prevent SHIV rebound in Rhesus macaques	1
Editorial JVE 8.4	1
PP5.2 – 00170 Plasma levels of Galectin-3 and -9 correlate with gut microbial dysregulation and residual mucosal SIV in Rhesus Macaques	1
OP 6.6 – 00134 Viral Suppression in SHIV-infected Rhesus Macaques following AAVmediated Delivery of Closer-to-germline Monoclonal Antibodies	1
Achieving the global agenda toward HIV cure calls for establishing a research-for-cure academy in West and Central Africa	1
Assessing favipiravir impact on SARS-CoV-2 transmission within households: Insights from a multi-center study (FaviPrev)	1
PP 2.15 – 00169 Macrophages are the primary source of virus in semen and male genital tract organs in acutely and chronically infected rhesus macaques	1
Editorial JVE 9.4	1
Hepatitis B prevalence in an endemic area of hepatitis C virus: A population-based study implicated in hepatitis elimination in Thailand	1
The ethical case for placebo control in HIV-cure-related studies with ART interruption	1
Management of chronic hepatitis B in Uganda: A five-year experience following the initiation of a national sensitization and care campaign	1
PP 4.4 – 00059 Quantification of HIV Reservoirs in Brain: focus in bystander damage	1
PP 1.41 – 00092 Spatial Transcriptomics and the Search for the Latent HIV-1 Cell Niche	1
OP 6.8 – 00102 In vivo evolution of env in SHIV-AD8-infected rhesus macaques after AAV-eCD4-Ig therapy	1
OP 3.2 – 00056 Clonally expanded HIV-1 proviruses with 5′-Leader defects can give rise to nonsuppressible residual viremia and complicate ART management	1
PP 3.12 – 00180 Distinct HIV-1 resistance profiles against bNAb in intact vs defective viral genomes	1
PP 1.6 – 00047LAIR-1 is a negative regulator of SIV-specific CD8 T cells during chronic SIV infection	1
3.4 – 00150 Unbiased Genome-Wide CRISPR Screens in Primary Human CD4+ T Cells Identify Novel Proviral and Anti-viral HIV Host Factors	1
PP 2.14 – 00162 Elucidating the effects of combination therapy with Venetoclax and IAP inhibitor AZD5582 in SIV-infected, ART-suppressed macaques	1
PP5.4 – 00017 Barcoded HIV-1 reveals proviruses associated with cell clonal proliferation or viremia have distinct chromatin patterns	1
PP 1.21 – 00118 Regulation of HIV-1 persistence by the CARD8 inflammasome	1
OP 2.4 – 00145 No Evidence of Ongoing Viral Replication in SIV-Infected Macaques on Combination Antiretroviral Therapy Initiated in the Chronic Phase of Infection Despite Elevated Residual Plasma Vira	1
OP 3.3 – 00030 Inducible replication-competent HIV proviruses persist in memory CD4+ T cells expressing high levels of the integrin VLA-4 (α4β1)	1
A liberalized approach to directly observed therapy for HCV retains excellent cure rates among PWID in Vienna	1
PP 2.9 – 00125 Impact of latency reversal agents on estrogen receptor alpha gene and protein expression	1
PP 4.18 – 00213 Dynamics and antiviral role of TOX+ TCF1+ CD39+ CD8 T cells in lymphoid tissue of SIV-infected rhesus macaques	1
5.3 – 00106 Macrophage-tropic TF SHIV D infected NHP model of reservoir persistence, decay and pathogenesis on suppressive anti-retroviral therapy	1
The central nervous system is a potential reservoir and possible origin of drug resistance in hepatitis B infection	1
PP 3.7 – 00128 Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomes	1
8.5 – 00015 Changes in the composition of HIV-1 reservoir of PWH on ART and dasatinib	1
Editorial Board	1
PP 4.5 – 00064 Differentiation Enhances Reactivation of Latent HIV-1 Reservoir in CD4+ T Cells in PLWH With > 4 Years of Viral Suppression	1
ST2.3 – 00128 Targeting Myeloid Reservoirs Harboring Replication-Competent HIV	1
PP 3.4 – 00079 HIV-1 clade C reservoir characteristics in early and chronic treated infection	1
PP 4.1 – 00013 Vaccine-mediated induction of elite control-associated CD8+ cytotoxic T lymphocytes in Mamu-B*08+ Indian rhesus macaques does not protect against intrarectal SIVmac239 acquisition	1
4.5 – 00020 Control of HIV infection is associated with enhanced CD8T cell functionality during consecutive analytical treatment interruptions	1
PP 7.10 – 00088 Macrophage-Tropic HIV-1 Variants Contribute to Pediatric Rebound Viremia off ART	1