OOIR: Observatory of International Research

Papers

(The median citation count of Military Medical Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
ADP-dependent glucokinase controls metabolic fitness in prostate cancer progression	348
Differential roles of RIG-I like receptors in SARS-CoV-2 infection	246
Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges	180
A cross-sectional study of olfactory and taste disorders among COVID-19 patients in China	167
Bone-organ axes: bidirectional crosstalk	106
Oral administration of asparagine and 3-indolepropionic acid prolongs survival time of rats with traumatic colon injury	76
Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia	72
Correction to: Bioengineered materials with selective antimicrobial toxicity in biomedicine	69
Explosive eye injuries: characteristics, traumatic mechanisms, and prognostic factors for poor visual outcomes	66
MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies	61
FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis	60
Introduction of monkeypox virus in Benin, 2022	44
Targeting the epigenome to reinvigorate T cells for cancer immunotherapy	43
N6-methyladenosine modification of CENPK mRNA by ZC3H13 promotes cervical cancer stemness and chemoresistance	42
The efficacy of tucatinib-based therapeutic approaches for HER2-positive breast cancer	42
A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities	35
Adipose tissue macrophages: implications for obesity-associated cancer	33
Recent advances in CRISPR-based genome editing technology and its applications in cardiovascular research	33
The correlation between gut microbiome and atrial fibrillation: pathophysiology and therapeutic perspectives	32
Advances in single-cell sequencing: insights from organ transplantation	32
The Frank-Starling mechanism is not enough: blood volume expansion prominently decreases pulmonary O2 uptake	31
Veterans utilizing a federally qualified health center: a clinical snapshot	30
Tackling exosome and nuclear receptor interaction: an emerging paradigm in the treatment of chronic diseases	29
Estimation of radiation-induced health hazards from a “dirty bomb” attack with radiocesium under different assault and rescue conditions	29
Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy	29

Expression dynamics of periodic transcripts during cancer cell cycle progression and their correlation with anticancer drug sensitivity	29
Artificial intelligence and machine learning for hemorrhagic trauma care	28
Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases	27
Research advances in smart responsive-hydrogel dressings with potential clinical diabetic wound healing properties	26
Immune cells: potential carriers or agents for drug delivery to the central nervous system	26
Guidance of development, validation, and evaluation of algorithms for populating health status in observational studies of routinely collected data (DEVELOP-RCD)	25
Ionizable drug delivery systems for efficient and selective gene therapy	25
Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases	24
Advances in the isolation, cultivation, and identification of gut microbes	24
Advances in the design and development of SARS-CoV-2 vaccines	24
A review on cell damage, viability, and functionality during 3D bioprinting	23
Recent developments in application of single-cell RNA sequencing in the tumour immune microenvironment and cancer therapy	23
RIG-I, a novel DAMPs sensor for myoglobin, activates NF-κB/caspase-3 signaling in CS-AKI model	23
Targeting the central and peripheral nervous system to regulate bone homeostasis: mechanisms and potential therapies	22
Pericytes protect rats and mice from sepsis-induced injuries by maintaining vascular reactivity and barrier function: implication of miRNAs and microvesicles	22
An unfolding monkeypox outbreak in Europe and beyond	22
Biomaterials science and surface engineering strategies for dental peri-implantitis management	21
Correction to: Pushing the frontiers of military medical excellence: updates, progress and future needs	21
Endophilin A2 controls touch and mechanical allodynia via kinesin-mediated Piezo2 trafficking	21
Disentangling the effects of PTSD from Gulf War Illness in male veterans via a systems-wide analysis of immune cell, cytokine, and symptom measures	21
Spatial transcriptomics: recent developments and insights in respiratory research	21
Antimicrobial peptides: mechanism of action, activity and clinical potential	19
Digital in-line holographic microscopy for label-free identification and tracking of biological cells	19
Bioactive peptides and proteins for tissue repair: microenvironment modulation, rational delivery, and clinical potential	19
Excellent effects and possible mechanisms of action of a new antibody–drug conjugate against EGFR-positive triple-negative breast cancer	19
Melatonin attenuates radiation-induced cortical bone-derived stem cells injury and enhances bone repair in postradiation femoral defect model	18
Secondary analysis of malaria rapid diagnostic tests from rounds 5–8 of WHO product testing with a focus on false-negative results	18
BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition	18
A comprehensive guide to miniaturized percutaneous nephrolithotomy: International Alliance of Urolithiasis (IAU) consensus on best practices	17
Global, regional, and national burden of kidney, bladder, and prostate cancers and their attributable risk factors, 1990–2019	14
Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition)	14
Multimodal therapy strategies based on hydrogels for the repair of spinal cord injury	13
Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options	13
Interferon-α stimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis	13
Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability	13
Immune checkpoint inhibition mediated with liposomal nanomedicine for cancer therapy	13
Insights gained from single-cell analysis of chimeric antigen receptor T-cell immunotherapy in cancer	13
Research on the development methodology for clinical practice guidelines for organic integration of traditional Chinese and Western medicine	13
Nanosensitizers for sonodynamic therapy for glioblastoma multiforme: current progress and future perspectives	12
CRISPR/Cas9 nickase mediated signal amplification integrating with the trans-cleavage activity of Cas12a for highly selective and sensitive detection of single base mutations	12
Exploring the diagnostic potential: magnetic particle imaging for brain diseases	12
Monitoring of urinary iodine concentration in naval pilots: should iodine be supplemented or limited at coastal stations?	12
Deep learning-based lung sound analysis for intelligent stethoscope	11
What benefit can be obtained from magnetic resonance imaging diagnosis with artificial intelligence in prostate cancer compared with clinical assessments?	11
Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis	11
A prediction model for moderate to severe acute kidney injury in people with heart failure	11
Frailty as a sequela of burn injury: a post hoc analysis of the “RE-ENERGIZE” multicenter randomized-controlled trial and the National Health Interview Survey	11
Antimicrobial resistance crisis: could artificial intelligence be the solution?	11
Deciphering the molecular interplay and tumorigenesis in hepatocellular carcinoma through insights into FBXL6 and KRASG12D	10
Pre-hospital application of REBOA for life-threatening hemorrhage	10

Cellular therapeutics and immunotherapies in wound healing – on the pulse of time?	10
The applied principles of EEG analysis methods in neuroscience and clinical neurology	10
The emerging role of Panx1 as a potential therapeutic target for chronic pain	10
Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week randomized, double-blind, placebo-controlled tr	9
Early burn wound excision in mass casualty events	9
Mechanism of lactic acidemia-promoted pulmonary endothelial cells death in sepsis: role for CIRP-ZBP1-PANoptosis pathway	9
Advancing space medicine: a global perspective on in-orbit research and future directions	9
Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges	9
Correction: International Alliance of Urolithiasis (IAU) consensus on miniaturized percutaneous nephrolithotomy	9
Poor sleep and decreased cortical thickness in veterans with mild traumatic brain injury and post-traumatic stress disorder	9
Global burden and cross-country inequalities in urinary tumors from 1990 to 2021 and predicted incidence changes to 2046	9
Multifaceted roles of extracellular RNAs in different diseases	9
Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways	9
Data mining in clinical big data: the frequently used databases, steps, and methodological models	9
Adhesive hydrogels in osteoarthritis: from design to application	8
Physical exercise reverses immuno-cold tumor microenvironment via inhibiting SQLE in non-small cell lung cancer	8
Cardiac-targeted PIASy gene silencing mediates deSUMOylation of caveolin-3 and prevents ischemia/reperfusion-induced Nav1.5 downregulation and ventricular arrhythmias	8
Management of regional citrate anticoagulation for continuous renal replacement therapy: guideline recommendations from Chinese emergency medical doctor consensus	8
Hydration status, body composition, and anxiety status in aeronautical military personnel from Spain: a cross-sectional study	8
FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury	8
Novel radiopaque ethanol injection: physicochemical properties, animal experiments, and clinical application in vascular malformations	7
Association of fluid balance trajectories with clinical outcomes in patients with septic shock: a prospective multicenter cohort study	7
Wave-shaped microfluidic chip assisted point-of-care testing for accurate and rapid diagnosis of infections	7
Global burden of benign prostatic hyperplasia, urinary tract infections, urolithiasis, bladder cancer, kidney cancer, and prostate cancer from 1990 to 2021	7
Adhesive cryogel particles for bridging confined and irregular tissue defects	7
Dementia in military and veteran populations: a review of risk factors—traumatic brain injury, post-traumatic stress disorder, deployment, and sleep	7
Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles	7
The implications of single-cell RNA-seq analysis in prostate cancer: unraveling tumor heterogeneity, therapeutic implications and pathways towards personalized therapy	7
Radiomics and radiogenomics: extracting more information from medical images for the diagnosis and prognostic prediction of ovarian cancer	6
Lethal means and suicide prevention among military veterans	6
Targeting mitochondrial quality control: new therapeutic strategies for major diseases	6
Aspartoacylase suppresses prostate cancer progression by blocking LYN activation	6
Bioengineered skin organoids: from development to applications	6
National age-specific mortality trends for cervical and breast cancers in urban–rural areas of China from 2009 to 2021: a population-based analysis	6
Correction to: Nanomedicine‐boosting icaritin-based immunotherapy of advanced hepatocellular carcinoma	6
Small molecules facilitate single factor-mediated sweat gland cell reprogramming	6
FOXO1-expressing neutrophils: a double-edged sword in traumatic brain injury	6
Adipsin inhibits Irak2 mitochondrial translocation and improves fatty acid β-oxidation to alleviate diabetic cardiomyopathy	6
Alleviating mitochondrial dysfunction in diabetic cardiomyopathy through the Adipsin and Irak2 pathways	6
Correction: Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)	6
Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations	6
Alteration of mitochondrial protein succinylation against cellular oxidative stress in cancer	6
Targeting PPARα in low ambient temperature exposure-induced cardiac dysfunction and remodeling	5
Exosomal mediators in sepsis and inflammatory organ injury: unraveling the role of exosomes in intercellular crosstalk and organ dysfunction	5
Military traumatic brain injury: a challenge straddling neurology and psychiatry	5
Elucidating regulatory processes of intense physical activity by multi-omics analysis	5
Monkeypox outbreak: A novel threat after COVID-19?	5
Applications and prospects of cryo-EM in drug discovery	5
Identification of antimalarial targets of chloroquine by a combined deconvolution strategy of ABPP and MS-CETSA	5
Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect	5
PANX1-mediated ATP release confers FAM3A’s suppression effects on hepatic gluconeogenesis and lipogenesis	5
Ultrasound-triggered microbubble destruction enhances the radiosensitivity of glioblastoma by inhibiting PGRMC1-mediated autophagy in vitro and in vivo	4
Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration	4
Exploring new horizons in CAR-based therapy for the treatment of thyroid-associated ophthalmopathy	4
Potential roles of vitamin D binding protein in attenuating liver injury in sepsis	4
Nanomedicine‐boosting icaritin-based immunotherapy of advanced hepatocellular carcinoma	4
Traumatic brain injury and sight loss in military and veteran populations– a review	4
The roles of exosomal immune checkpoint proteins in tumors	4
Exosome autoantibody biomarkers for detection of lung cancer	4
AKR1C3 as a therapeutic target to overcome erlotinib resistance in lung adenocarcinoma	4
Heat exposure and hospitalizations for chronic kidney disease in China: a nationwide time series study in 261 major Chinese cities	4
Fostering hope and recovery: enhancing psychological resources in military personnel with post-traumatic stress disorder	4
Tumor dormancy and relapse: understanding the molecular mechanisms of cancer recurrence	4
Cardiovascular adaptations and pathological changes induced by spaceflight: from cellular mechanisms to organ-level impacts	4
RARRES2’s impact on lipid metabolism in triple-negative breast cancer: a pathway to brain metastasis	4
Short-term suborbital space flight curtails astronauts’ dopamine levels increasing cortisol/BDNF and prompting pro-oxidative/inflammatory milieu	4
Caveolin-1 is critical for hepatic iron storage capacity in the development of nonalcoholic fatty liver disease	4