OOIR: Observatory of International Research

Papers

(The TQCC of BMJ Open Respiratory Research is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Extracorporeal CO₂ removal in acute exacerbation of COPD unresponsive to non-invasive ventilation	85
Bagasse dust exposure and chronic respiratory symptoms among workers in the Metehara and Wonji sugar factories in Ethiopia: a longitudinal study design	72
Methamphetamine-associated pulmonary arterial hypertension: data from the national biological sample and data repository for pulmonary arterial hypertension (PAH Biobank)	60
Comparing the impact of targeting limited driving pressure to low tidal volume ventilation on mortality in mechanically ventilated adults with COVID-19 ARDS: an exploratory target trial emulation	50
Genomic testing for children with interstitial and diffuse lung disease (chILD): parent satisfaction, understanding and health-related quality of life	48
Differences in uni-dimensional breathlessness measures and thresholds for clinical response in a randomised controlled trial in people with chronic breathlessness: an exploratory study	45
Differences in risk indicators associated with electronic cigarette use and tobacco smoking among adolescents and young people in Nigeria	45
Comparison of the efficacy of novel two covering methods for spontaneous pneumothorax: a multi-institutional study	42
Association between birth weight and chronic obstructive pulmonary disease in the UK Biobank: a prospective cohort study	38
Evaluation of the Norwegian version of the Dyspnoea-12 questionnaire in patients with COPD	38
Malignant pleural mesothelioma patients’ experience by gender: findings from a cross-sectional UK-national questionnaire	34
Protection conferred by SARS-CoV-2 infection across a spectrum of reinfection symptoms and severities	33
Chronic obstructive pulmonary disease is a risk factor for non-tuberculous mycobacterial pulmonary disease: a population-based matched cohort study	32
Effect of a home-based inspiratory muscle training programme on functional capacity in postdischarged patients with long COVID: the InsCOVID trial	31
Elucidating the risk of cardiopulmonary consequences of an exacerbation of COPD: results of the EXACOS-CV study in Germany	29
Antibody responses and risk factors associated with impaired immunological outcomes following two doses of BNT162b2 COVID-19 vaccination in patients with chronic pulmonary diseases	28
Impact of early caffeine administration on respiratory outcomes in very preterm infants initially receiving invasive mechanical ventilation	26
Characterisation of patients with chronic obstructive pulmonary disease initiating single-device inhaled corticosteroids/long-acting β₂-agonist dual therapy in a primary care setting in Eng	25
Temperature synchronisation of circadian rhythms in primary human airway epithelial cells from children	23
Association of high-sensitivity CRP and FEV1%pred: a study on non-pulmonary disease in a population in Beijing, China	23
Rate of severe exacerbations, healthcare resource utilisation and clinical outcomes in patients with COPD in low-income and middle-income countries: results from the EXACOS International Study	22
What if… your research is suddenly affiliated with a tobacco manufacturing company?	22
Influencing factors of sedentary behaviour in people with chronic obstructive pulmonary disease: a systematic review	22
Impact of COVID-19 on people with asthma: a mixed methods analysis from a UK wide survey	21
Association between mental health disorders and asthma exacerbations in adults: a retrospective cohort study in UK primary care	21

Serum KL-6 levels predict clinical outcomes and are associated with MUC1 polymorphism in Japanese patients with COVID-19	20
Therapeutic effects of fatty acid binding protein 1 in mice with pulmonary fibrosis by regulating alveolar epithelial regeneration	20
Hospital-level variation in practices and outcomes for patients with severe acute exacerbations of idiopathic pulmonary fibrosis: a retrospective multicentre cohort study	20
Diagnostic delay in IPF impacts progression-free survival, quality of life and hospitalisation rates	19
Contribution of collagen XIII to lung function and development of pulmonary fibrosis	19
Performance evaluation of human cough annotators: optimal metrics and sex differences	18
Pragmatic randomised controlled trials in COPD and asthma: how to guide clinical practice	18
Withdrawal of inhaled corticosteroids from patients with COPD with mild or moderate airflow limitation in primary care: a feasibility randomised trial	18
Haemoglobin value and red blood cell transfusions in prolonged weaning from mechanical ventilation: a retrospective observational study	18
IPDMA – RADICAL – NSCLC: individual participant data meta-analysis and systematic review of radical local therapy for oligometastatic NSCLC	18
Assessing the health impacts of parenthood on people with cystic fibrosis: the HOPeCF prospective cohort protocol	18
Lung Health Check pilot: Ireland’s flagship lung cancer screening trial	18
Effect of stellate ganglion block on perioperative myocardial injury following thoracoscopic surgery for lung cancer (SGBMI): protocol for a single-centre, randomised controlled trial	17
Pulmonary hypertension survival and hospitalisations in people living with HIV: a systematic review and meta-analysis	17
Hospitalisations and fatality due to respiratory diseases according to a national database in Brazil: a longitudinal study	17
Factors associated with undiagnosed COPD in patients hospitalised for severe COPD exacerbation	16
Correlation of programmed death-ligand 1 expression in tumour cells between diagnostic small biopsies performed by radial EBUS and surgical specimens of peripheral lung cancer	16
National trend in the prevalence and mortality of COPD in South Korea from 2008 to 2017	16
Reliability and responsiveness of the D12 and validity of its scores as a measure of dyspnoea severity in patients with rheumatoid arthritis-related interstitial lung disease	16
Design of a phase III, double-blind, randomised, placebo-controlled trial of BI 1015550 in patients with idiopathic pulmonary fibrosis (FIBRONEER-IPF)	15
The advance care planning in respiratory rehabilitation of chronic obstructive pulmonary disease (COPD) patients	15
Perinatal and early life factors and asthma control among preschoolers: a population-based retrospective cohort study	15
Chemical exposure and alveolar macrophages responses: ‘the role of pulmonary defense mechanism in inhalation injuries’	15
Clustering-based COPD subtypes have distinct longitudinal outcomes and multi-omics biomarkers	15
Global, regional and national burden of asthma from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021	14
Bicarbonate from arterial blood gas analysis as predictor of sleep-related hypoventilation: a diagnostic accuracy study	14
Determining what patients admitted with a chronic obstructive pulmonary disease (COPD) exacerbation will use for remote clinical monitoring: a patient engagement survey	14
Comparison of stability of the GOLD and STAR lung function classification for chronic obstructive pulmonary disease	14
Assessment of peak inspiratory flow in patients with chronic obstructive pulmonary disease: a multicentre, observational, prospective, real-life study	14
Under the weather: an epidemic thunderstorm asthma event in Leicester, June 2023	14
Pleural fluid C-C class chemokines 22 and pleural effusion due to heart failure: a prospective and double-blind diagnostic accuracy test	13
Clinical manifestations and prognostic factors analysis of patients hospitalised with acute exacerbation of idiopathic pulmonary fibrosis and other interstitial lung diseases	13
Inhaler use and their carbon footprint in Germany: a 10-year analysis (2013–2022)	13
Integrating specialist palliative care to improve care and reduce suffering: cystic fibrosis (InSPIRe:CF) – study protocol for a multicentre randomised clinical trial	13
Considerations for the use of inhaled antibiotics for Pseudomonas aeruginosa in people with cystic fibrosis receiving CFTR modulator therapy	13
Single and multiple breath nitrogen washout compared with the methacholine test in patients with suspected asthma and normal spirometry	12
PD-1 inhibitor plus chemotherapy versus bevacizumab plus chemotherapy in patients with advanced non-squamous non-small-cell lung cancer: a pooled analysis of three randomised trials	12
Incidence and prevalence of interstitial lung diseases worldwide: a systematic literature review	12
Impact of patient support programmes among patients with severe asthma treated with biological therapies: a systematic literature review and indirect treatment comparison	12
Self-management programme of activity coping and education—SPACE for COPD(C)—in primary care: a pragmatic randomised trial	12
Design of a phase III, double-blind, randomised, placebo-controlled trial of BI 1015550 in patients with progressive pulmonary fibrosis (FIBRONEER-ILD)	12
Reference equations for pulmonary diffusing capacity using segmented regression show similar predictive accuracy as GAMLSS models	12
Identifying the population to be targeted in a lung cancer screening programme in Denmark	12
Towards codesign in respiratory care: development of an implementation-ready intervention to improve guideline-adherent adult asthma care across primary and secondary care settings (The SENTINEL Proje	12
DIGIPREDICT: physiological, behavioural and environmental predictors of asthma attacks—a prospective observational study using digital markers and artificial intelligence—study protocol	12
Characteristics of pulse oximetry and arterial blood gas in patients with fibrotic interstitial lung disease	12
T ₂ *-weighted oxygen-enhanced pulmonary MRI in COPD is linked to resting and exertional functional measurements	11
Clinical features and 1-year outcomes of chronic bronchitis in participants with normal spirometry: results from the ECOPD study in China	11
Effect of high-flow nasal cannula versus non-invasive ventilation after extubation on successful extubation in obese patients: a retrospective analysis of the MIMIC-IV database	11
Prevalence and clinical characteristics of non-malignant CT detected incidental findings in the SUMMIT lung cancer screening cohort	11

Estimated costs of tuberculosis services in Brazil, 2023	11
Twelve barriers to COPD diagnosis in France: a comparative qualitative study	11
Treatment patterns and frequency of key outcomes in acute severe asthma in children: a Paediatric Research in Emergency Departments International Collaborative (PREDICT) multicentre cohort study	11
Reducing exacerbations in children and adults with primary ciliary dyskinesia using erdosteine and/or azithromycin therapy (REPEAT trial): study protocol for a multicentre, double-blind, double-dummy,	11
Understanding facilitators and barriers to oxygen therapy for patients with interstitial lung disease	11
Pharmacokinetics and pharmacodynamics of inhaled molgramostim in healthy people	11
Liberation from invasive mechanical ventilation: a nationwide survey among intensive care units in the Netherlands	11
Non-invasive surrogate markers of pulmonary hypertension are associated with poor survival in patients with cancer	11
Reduced tidal volume-inflection point and elevated operating lung volumes during exercise in females with well-controlled asthma	11
Estimating rate of lung function change using clinical spirometry data	11
Bidirectional relationship between sleep problems and long COVID: a longitudinal analysis of data from the COVIDENCE UK study	11
Real-world impact of the fixed-dose combination on improving treatment outcomes of drug-susceptible tuberculosis: a comparative study using multiyear national tuberculosis patient data	11
Right ventricular functional recovery assessment with stress echocardiography and cardiopulmonary exercise testing after pulmonary embolism: a pilot prospective multicentre study	10
Bronchial smooth muscle cell in asthma: where does it fit?	10
Previously treated latent tuberculosis infection is associated with less severe acute COVID-19: a cohort study	10
Socioeconomic burden of cystic fibrosis in Canada	10
Effect of a home-based inspiratory muscular training programme on functional capacity in patients with chronic COVID-19 after a hospital discharge: protocol for a randomised control trial (InsCOVID tr	10
Real-life effects of benralizumab on airway oscillometry in severe eosinophilic asthma	10
Prevalence and burden of COPD misclassification in the Canadian Longitudinal Study on Aging (CLSA)	10
Randomised controlled trial of perinatal vitamin D supplementation to prevent early-onset acute respiratory infections among Australian First Nations children: the ‘D-Kids’ study protocol	10
Exercise oxygen desaturation is a predictor of cardiopulmonary complications after lung resection	10
Incidence and outcomes of pulmonary hypertension in the Ireland	10
Respiratory function and CT abnormalities among survivors of COVID-19 pneumonia: a nationwide follow-up study	10
CC-90001, a c-Jun N-terminal kinase (JNK) inhibitor, in patients with pulmonary fibrosis: design of a phase 2, randomised, placebo-controlled trial	10
Asthma control in severe asthma and occupational exposures to inhalable asthmagens	10
Preterm birth, birth weight, infant weight gain and their associations with childhood asthma and spirometry: a cross-sectional observational study in Nairobi, Kenya	10
Prevalence and predictors of tuberculosis infection among people living with HIV in a high tuberculosis burden context	10
What is the true target population for biologics in real-life COPD or asthma-COPD overlap patients?	10
Deep learning with test-time augmentation for radial endobronchial ultrasound image differentiation: a multicentre verification study	10
Correction: Post-COVID-19 assessment in a specialist clinical service: a 12-month, single-centre, prospective study in 1325 individuals	10
Prevalence of pre-existing lung diseases and their association with income level among patients with lung cancer: a nationwide population-based case-control study in South Korea	10
Non-cystic fibrosis bronchiectasis in Taiwan	9
Renin–angiotensin–system inhibitors and the risk of exacerbations in chronic obstructive pulmonary disease: a nationwide registry study	9
Trends and determinants of unfavourable outcomes in paediatric tuberculosis: insights from a 20-year cohort in Cameroon	9
Early experiences of the Your COVID Recovery^® digital programme for individuals with long COVID	9
Robust positive association between serum urate and the risk of chronic obstructive pulmonary disease: hospital-based cohort and Mendelian randomisation study	9
Association of C-reactive protein with cause, duration and severity of lower respiratory infections in primary care: a prospective cohort study	9
Registry-based study in people with cystic fibrosis and an R117H variant treated with ivacaftor	9
Association of socioeconomic status with respiratory mortality and hospitalisations in COPD: a nationwide cohort study	9
Surveillance towards preventing paediatric incidence of respiratory syncytial virus attributable respiratory tract infection in primary and secondary/tertiary healthcare settings in Merseyside, Cheshi	9
Chronic respiratory disease observatory for Africa (CHEST-Africa): study protocol for the prevalence, determinants and economic impacts of asthma and COPD in Africa	9
Exploring barriers and facilitators for implementation of novel image-guided minimally invasive procedures: nationwide experiences on navigation bronchoscopy	9
Phase-resolved MRI for measurement of pulmonary perfusion and ventilation defects in comparison with dynamic contrast-enhanced MRI and ¹²⁹Xe MRI	9
Frequency and severity of COPD exacerbations and future risk of exacerbations and mortality: an observational cohort study in Canada	9
Childhood ‘bronchitis’ and respiratory outcomes in middle-age: a prospective cohort study from age 7 to 53 years	9
ARDS during haematopoietic reconstruction after allogeneic haematopoietic stem cell transplantation (allo-HSCT) in non-child patients: based on the new global definition	9
Lower geriatric nutritional risk index is associated with a higher risk of all-cause mortality in patients with chronic obstructive pulmonary disease: a cohort study from the National Health and Nutri	9
Rehabilitation outcomes for people with lung cancer (UNITE): protocol for the development of a core outcome set	9
Why do patients with DR-TB do not complete their treatment? Findings of a qualitative study from Pakistan	9
Employment of artificial intelligence for early lung cancer diagnosis: a retrospective cohort study	8
Pim1 inactivating induces RUNX3 upregulation that improves/alleviates airway inflammation and mucus hypersecretion in vitro and in vivo	8
Bronchial hyper-reactivity in young adults after hospitalisation for bronchiolitis in infancy	8
Compensatory function change by segment-counting method in predicted postoperative pulmonary function at 1 year after surgery: systematic review and meta-analysis	8
Beyond direct costs: individual and societal financial burden of asthma in young adults in a Danish nationwide study	8
Association between serum uric acid/serum creatinine ratios and lung function in the general American population: National Health and Nutrition Examination Survey (NHANES), 2007–2012	8
Managing moderate-to-severe paediatric asthma: a scoping review of the efficacy and safety of fluticasone propionate/salmeterol	8
Phenotyping the Responses to Systemic Corticosteroids in the Management of Asthma Attacks (PRISMA): protocol for an observational and translational pilot study	8
Digitally recorded and remotely classified lung auscultation compared with conventional stethoscope classifications among children aged 1–59 months enrolled in the Pneumonia Etiology Research for Chil	8
Hospital-based multidisciplinary lung cancer care in Australia: a survey of the landscape in 2021	8
Sublobar resection or lobectomy for stage Ia non-small cell lung cancer: a systematic review and meta-analysis	8
Adherence to application technique of inhaled corticosteroid in patients with asthma and COVID-19 improves outcomes	8
Adherence to COVID-19 preventive measures and associated factors among high school students in Northwest Ethiopia: a cross-sectional study	8
Vitamin D status: a U-shaped relationship for SARS-CoV-2 seropositivity in UK healthcare workers	8
Developing an intrasalivary gland botox service for patients receiving long-term non-invasive ventilation at home: a single-centre experience	8
Transitioning from hospital to home with non-invasive ventilation: who benefits? Results of a cohort study	8
Reductions in inhaler greenhouse gas emissions by addressing care gaps in asthma and chronic obstructive pulmonary disease: an analysis	8
Assessment of the clinical prognosis of patients with chronic obstructive pulmonary disease using combined blood and sputum eosinophil counts	8
Effect of a postoperative home-based exercise and self-management programme on physical function in people with lung cancer (CAPACITY): protocol for a randomised controlled trial	8
Comparing the CO ₂ emissions of metered dose inhalers and dry powder inhalers: a cross-sectional environmental impact analysis of asthma and COPD the	8
Comorbidities associated with adult asthma: a population-based matched cohort study in Finland	7
Association between antibiotics and asthma risk among adults aged over 40 years: a nationally representative retrospective cohort study	7
Temporal complexity in missed doses of rifampicin-sensitive anti-tuberculosis treatment: a prospective cohort study in Tanzania	7
Chronic obstructive pulmonary disease as a risk factor for cognitive impairment: a systematic review and meta-analysis	7
Phase 2 study design and analysis approach for BBT-877: an autotaxin inhibitor targeting idiopathic pulmonary fibrosis	7
Real-world impact of ivacaftor in people with cystic fibrosis and select ivacaftor-responsive mutations	7
Automated audit of hospital oxygen use devised during the COVID-19 pandemic	7
The randomised thoracoscopic talc poudrage+indwelling pleural catheters versus thoracoscopic talc poudrage only in malignant pleural effusion trial (TACTIC): study protocol for a randomised controlled	7
Factors associated with asthma attack recurrence in Ecuadorian children: longitudinal study of potential impact of the COVID-19 pandemic lockdown	7
Scoping review of exposure questionnaires and surveys in interstitial lung disease	7
Use of supplemental oxygen therapy in idiopathic pulmonary fibrosis: an observational real-life study in 16 003 patients	7

Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active	7
Isolated small airways obstruction predicts future chronic airflow obstruction: a multinational longitudinal study	7
Prospectively evaluating maternal and fetal outcomes in the era of CFTR modulators: the MAYFLOWERS observational clinical trial study design	7
Cone beam CT-guided navigation bronchoscopy: a cost-effective alternative to CT-guided transthoracic biopsy for diagnosis of peripheral pulmonary nodules	7
Chronic obstructive pulmonary disease trajectory: severe exacerbations and dynamic change in health-related quality of life	7