Pharmacology Research & Perspectives

Article	Citations
Diversity of molecular targets and signaling pathways for CBD	144
Molnupiravir: A new candidate for COVID‐19 treatment	82
Effect of remimazolam induction on hemodynamics in patients undergoing valve replacement surgery: A randomized, double‐blind, controlled trial	80
“LONG COVID”—A hypothesis for understanding the biological basis and pharmacological treatment strategy	74
Drug discovery: Insights from the invertebrate Caenorhabditis elegans	57
The antimicrobial effect behind Cannabis sativa	45
Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent	38
Kidney damage from nonsteroidal anti‐inflammatory drugs—Myth or truth? Review of selected literature	37
Inter‐ethnic differences in pharmacokinetics—is there more that unites than divides?	36
Strategies to apply 3Rs in preclinical testing	36
Histamine in cancer immunology and immunotherapy. Current status and new perspectives	33
Biological drug therapy for ocular angiogenesis: Anti‐VEGF agents and novel strategies based on nanotechnology	31
Probiotic lactobacilli in formulas and hygiene products for the health of the urogenital tract	30
Spermidine and spermine exert protective effects within the lung	29
An overview of diagnosis and management of drug‐induced hypomagnesemia	29
The impact of vitamin D supplementation as an adjuvant therapy on clinical outcomes in patients with severe atopic dermatitis: A randomized controlled trial	28
The interacting physiology of COVID‐19 and the renin‐angiotensin‐aldosterone system: Key agents for treatment	28
Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview	28
Identification of the metabolites of ivermectin in humans	26
Pros and cons for statins use and risk of Parkinson's disease: An updated perspective	26
Phase 1 study in healthy participants of the safety, pharmacokinetics, and pharmacodynamics of enpatoran (M5049), a dual antagonist of toll‐like receptors 7 and 8	25
Gut microbiota disorder caused by diterpenoids extracted from Euphorbia pekinensis aggravates intestinal mucosal damage	24
Alleviation of cisplatin‐induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase‐3 activity	24
CCN5 activation by free or encapsulated EGCG is required to render triple‐negative breast cancer cell viability and tumor progression	23
Phase I evaluation of the safety, tolerability, and pharmacokinetics of GSK3640254, a next‐generation HIV‐1 maturation inhibitor	23

Systems analysis shows that thermodynamic physiological and pharmacological fundamentals drive COVID‐19 and response to treatment	22
The therapeutic effects of naringenin on bronchial pneumonia in children	21
Unraveling the complexity of therapeutic drug monitoring for monoclonal antibody therapies to individualize dose in oncology	21
The role of sex, age and genetic polymorphisms of CYP enzymes on the pharmacokinetics of anticholinergic drugs	20
Penetration, distribution, and elimination of remofuscin/soraprazan in Stargardt mouse eyes following a single intravitreal injection using pharmacokinetics and transmission electron microscopic autor	20
Pharmacological hypotheses: Is acetaminophen selective in its cyclooxygenase inhibition?	20
Drp1‐dependent peptide reverse mitochondrial fragmentation, a homeostatic response in Friedreich ataxia	19
Development of a machine learning algorithm for early detection of opioid use disorder	19
Phase 1 study to access safety, tolerability, pharmacokinetics, and pharmacodynamics of kynurenine in healthy volunteers	19
Design of a foundational sciences curriculum: Applying the ICAP framework to pharmacology education in integrated medical curricula	18
Protective effect of baicalin against pulmonary arterial hypertension vascular remodeling through regulation of TNF‐α signaling pathway	18
Hearing loss: The final frontier of pharmacology	17
Circ_0001821 knockdown suppresses growth, metastasis, and TAX resistance of non‐small‐cell lung cancer cells by regulating the miR‐526b‐5p/GRK5 axis	17
Cannabidiol‐mediated RISK PI3K/AKT and MAPK/ERK pathways decreasing reperfusion myocardial damage	17
p‐cymene impairs SARS‐CoV‐2 and Influenza A (H1N1) viral replication: In silico predicted interaction with SARS‐CoV‐2 nucleocapsid protein and H1N1 nucleoprotein	17
Chemogenetic stimulation of the Gi pathway in astrocytes suppresses neuroinflammation	17
The 5‐HT2C receptor as a therapeutic target for alcohol and methamphetamine use disorders: A pilot study in treatment‐seeking individuals	16
Addressing opioid tolerance and opioid‐induced hypersensitivity: Recent developments and future therapeutic strategies	16
Long‐term benzodiazepines and z‐drug prescribing in Australian general practice between 2011 and 2018: A national study	15
Nanoparticle delivery system, highly active antiretroviral therapy, and testicular morphology: The role of stereology	15
Dexmedetomidine ameliorates high‐fat diet‐induced nonalcoholic fatty liver disease by targeting SCD1 in obesity mice	15
Characterization of TR‐107, a novel chemical activator of the human mitochondrial protease ClpP	15
Nobiletin ameliorates cardiac impairment and alleviates cardiac remodeling after acute myocardial infarction in rats via JNK regulation	15
Risk of genital and urinary tract infections associated with SGLT‐2 inhibitors as an add‐on therapy to metformin in patients with type 2 diabetes mellitus: A retrospective cohort study in Korea	14
Self‐medication among pregnant women attending outpatients' clinics in northern Jordan‐a cross‐sectional study	14
Recombinant botulinum neurotoxin serotype A1 in vivo characterization	14
Spinal glial cells in itch modulation	14
Defining and unpacking the core concepts of pharmacology education	14
Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID‐19	14
Carrageenan nasal spray may double the rate of recovery from coronavirus and influenza virus infections: Re‐analysis of randomized trial data	14
Clinical effect of different doses of ciprofol for induction of general anesthesia in elderly patients: A randomized, controlled trial	13
The contribution of nano‐based strategies in overcoming ceftriaxone resistance: a literature review	13
Targeting host cell proteases as a potential treatment strategy to limit the spread of SARS‐CoV‐2 in the respiratory tract	13
The signaling and selectivity of α‐adrenoceptor agonists for the human α2A, α2B and α2C‐adrenoceptors and comparison with human α1 and β‐adrenoceptors	13
Drug repurposing strategies of relevance for Parkinson’s disease	13
Impact of the mouse estrus cycle on cannabinoid receptor agonist‐induced molecular and behavioral outcomes	13
Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion	13
New insights into the role of melatonin in diabetic cardiomyopathy	13
Identifying the core concepts of pharmacology education	12
Side‐effects of carbetocin to prevent postpartum hemorrhage: A systematic review and meta‐analysis of randomized controlled trials	12
Association of income and educational levels with adherence to direct oral anticoagulant therapy in patients with incident atrial fibrillation: A Finnish nationwide cohort study	12
SMTP‐44D improves diabetic neuropathy symptoms in mice through its antioxidant and anti‐inflammatory activities	12
Long noncoding RNA highly upregulated in liver cancer promotes the progression of hepatocellular carcinoma and attenuates the chemosensitivity of oxaliplatin by regulating miR‐383‐5p/vesicle‐associate	12
Polypharmacology of clinical sodium glucose co‐transport protein 2 inhibitors and relationship to suspected adverse drug reactions	12
The selectivity of α‐adrenoceptor agonists for the human α1A, α1B, and α1D‐adrenoceptors	12
Chronic cerebral aspects of long COVID, post‐stroke syndromes and similar states share their pathogenesis and perispinal etanercept treatment logic	12
Mizagliflozin, a selective SGLT1 inhibitor, improves vascular cognitive impairment in a mouse model of small vessel disease	12
Real‐life efficacy and safety of elexacaftor/tezacaftor/ivacaftor on severe cystic fibrosis lung disease patients	11
The effect of Fingolimod on patients with moderate to severe COVID‐19	11
Nucleoside analog GS‐441524: pharmacokinetics in different species, safety, and potential effectiveness against Covid‐19	11

Impact of polymorphisms of pharmacokinetics‐related genes and the inflammatory response on the metabolism of voriconazole	11
Exploring the Food and Drug Administration’s review and approval of Entresto (sacubitril/valsartan)	11
Use of levothyroxine among pregnant women with subclinical hypothyroidism in the United Kingdom: A population‐based assessment	11
Correlation of functional and radioligand binding characteristics of GPER ligands confirming aldosterone as a GPER agonist	11
Nonsteroidal anti‐inflammatory drugs in acute viral respiratory tract infections: An updated systematic review	11
In vitro evaluation suggests fenfluramine and norfenfluramine are unlikely to act as perpetrators of drug interactions	11
The affinity and selectivity of α‐adrenoceptor antagonists, antidepressants and antipsychotics for the human α2A, α2B, and α2C‐adrenoceptors and comparison with human α1 and β‐adrenoceptors	11
Long‐term antagonism and allosteric regulation of mu opioid receptors by the novel ligand, methocinnamox	10
Synthesis, in vitro bioassays, and computational study of heteroaryl nitazoxanide analogs	10
Upregulated UCA1 contributes to oxaliplatin resistance of hepatocellular carcinoma through inhibition of miR‐138‐5p and activation of AKT/mTOR signaling pathway	10
Pharmacokinetic, pharmacodynamic, and pharmacogenetic assays to monitor clopidogrel therapy	10
Characterization of the absorption, metabolism, excretion, and mass balance of gefapixant in humans	10
ZINC40099027 activates human focal adhesion kinase by accelerating the enzymatic activity of the FAK kinase domain	10
Psychedelic‐assisted therapy for functional neurological disorders: A theoretical framework and review of prior reports	10
Honokiol attenuate the arsenic trioxide‐induced cardiotoxicity by reducing the myocardial apoptosis	10
Pharmacological inhibition of STAT3 by BP‐1‐102 inhibits intracranial aneurysm formation and rupture in mice through modulating inflammatory response	10
Community pharmacists workforce readiness to deliver vaccination services: A cross‐sectional study from Jordan	10
Benefits and adverse effects of sacubitril/valsartan in patients with chronic heart failure: A systematic review and meta‐analysis	10
Prescribing cascades in community‐dwelling adults: A systematic review	10
[8]‐Gingerol exerts anti‐myocardial ischemic effects in rats via modulation of the MAPK signaling pathway and L‐type Ca2+ channels	10
Alignment between outcomes and minimal clinically important differences in the Dutch type 2 diabetes mellitus guideline and healthcare professionals’ preferences	10
Declines and pronounced regional disparities in meperidine use in the United States	9
SoxE group transcription factor Sox8 promotes astrocytic differentiation of neural stem/precursor cells downstream of Nfia	9
Pitolisant, a wake‐promoting agent devoid of psychostimulant properties: Preclinical comparison with amphetamine, modafinil, and solriamfetol	9
Nuclear receptors of NR1 and NR4 subfamilies in the regulation of microglial functions and pathology	9
Nicorandil inhibits cardiomyocyte apoptosis and improves cardiac function by suppressing the HtrA2/XIAP/PARP signaling after coronary microembolization in rats	9
Anticancer effects of myricetin derivatives in non‐small cell lung cancer in vitro and in vivo	9
Suspected adverse drug reactions of the type 2 antidiabetic drug class dipeptidyl‐peptidase IV inhibitors (DPP4i): Can polypharmacology help explain?	9
Chronic everolimus treatment of high‐fat diet mice leads to a reduction in obesity but impaired glucose tolerance	9
Bridging the gap: Can International Consortium of Health Outcomes Measurement standard sets align outcomes accepted for regulatory and health technology assessment decision‐making of oncology medicine	9
Dexamethasone promotes the endoplasmic reticulum stress response of bone marrow mesenchymal stem cells by activating the PERK‐Nrf2 signaling pathway	9
Subtype selective fluorescent ligands based on ICI 118,551 to study the human β2‐adrenoceptor in CRISPR/Cas9 genome‐edited HEK293T cells at low expression levels	9
In vitro evaluation of fenfluramine and norfenfluramine as victims of drug interactions	9
The efficacy and safety of fingolimod plus standardized treatment versus standardized treatment alone for acute ischemic stroke: A systematic review and meta‐analysis	8
A practical treatment for COVID‐19 and the next pandemic	8
Developing a new undergraduate pharmacology core curriculum: The British Pharmacological Society Delphi Method	8
Measurement of total liver blood flow in intact anesthetized rats using ultrasound imaging	8
Induced fit versus conformational selection: From rate constants to fluxes… and back to rate constants	8
Stathmin dynamics modulate the activity of eribulin in breast cancer cells	8
Augmented renal clearance in critically ill patients with cancer (ARCCAN Study): A prospective observational study evaluating prevalence and risk factors	8
Patients receiving a high burden of antibiotics in the community in Spain: a cross‐sectional study	8
The relationship between vancomycin AUC/MIC and trough concentration, age, dose, renal function in Chinese critically ill pediatric patients	8
Factors associated with fluoxetine and norfluoxetine plasma concentrations and clinical response in Mexican patients with mental disorders	8
Ranitidine and the incidence of hypersensitivity reactions to paclitaxel: A retrospective cohort study	8
Casticin protected against neuronal injury and inhibited the TLR4/NF‐κB pathway after middle cerebral artery occlusion in rats	8
Jadomycins: A potential chemotherapy for multi‐drug resistant metastatic breast cancer	8
2‐Deoxy‐d‐glucose induces deglycosylation of proinflammatory cytokine receptors and strongly reduces immunological responses in mouse models of inflammation	8
Effect of a common missense variant in LIPA gene on fatty liver disease and lipid phenotype: New perspectives from a single‐center observational study	8
Untargeted metabolomics identifies the potential role of monocarboxylate transporter 6 (MCT6/SLC16A5) in lipid and amino acid metabolism pathways	8
Health service use and costs associated with fluoroquinolone‐related tendon injuries	8
Dose‐dependent effects of esketamine on brain activity in awake mice: A BOLD phMRI study	8
M1 muscarinic receptor activation decreases alcohol consumption via a reduction in consummatory behavior	8
Pan‐cancer population pharmacokinetics and exposure‐safety and ‐efficacy analyses of atezolizumab in patients with high tumor mutational burden	8
Application of a high‐resolution in vitro human MDR1‐MDCK assay and in vivo studies in preclinical species to improve prediction of CNS drug penetration	7
Immunomodulation induced by central nervous system‐related peptides as a therapeutic strategy for neurodegenerative disorders	7
Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically ill children: An observational, prospective, controlled study	7
The pharmaceutical excipient PEG400 affect the absorption of baicalein in Caco‐2 monolayer model by interacting with UDP‐glucuronosyltransferases and efflux transport proteins	7
Prevention of bleomycin‐induced lung fibrosis via inhibition of the MRTF/SRF transcription pathway	7
In vitro investigations into the roles of CYP450 enzymes and drug transporters in the drug interactions of zanubrutinib, a covalent Bruton's tyrosine kinase inhibitor	7
Goshajinkigan attenuates paclitaxel‐induced neuropathic pain via cortical astrocytes	7
Xanthatin suppresses proliferation and tumorigenicity of glioma cells through autophagy inhibition via activation of the PI3K‐Akt–mTOR pathway	7
The importance of collaboratively designing pharmacology education programs	7
Antibiotic use and associated factors in adult outpatients from 2000 to 2019	7
Intervention by clinical pharmacists can improve blood glucose fluctuation in patients with diabetes and acute myocardial infarction: A propensity score‐matched analysis	7
Optimization of dose and route of administration of the P‐glycoprotein inhibitor, valspodar (PSC‐833) and the P‐glycoprotein and breast cancer resistance protein dual‐inhibitor, elacridar (GF120918) a	7
Pharmacokinetics of buprenorphine in pregnant sheep after intravenous injection	7
EVT‐701 is a novel selective and safe mitochondrial complex 1 inhibitor with potent anti‐tumor activity in models of solid cancers	7
Real clinical impact of drug–drug interactions of immunosuppressants in transplant patients	7
Identification of an irreversible PPARγ antagonist with potent anticancer activity	7
Tyrosine kinase inhibitors targeting vascular endothelial growth factor and the risk of aortic dissection—A pharmacovigilance analysis	7
Sirt3 regulates adipogenesis and adipokine secretion via its enzymatic activity	7
Statin withdrawal and treating COVID‐19 patients	7
Identification of the organic anion transporting polypeptides responsible for the hepatic uptake of the major metabolite of epyrifenacil, S‐3100‐CA, in mice	7
Pharmacokinetics and safety of TCMCB07, a melanocortin‐4 antagonist peptide in dogs	6
How to approach a study in ethnopharmacology? Providing an example of the different research stages for newcomers to the field today	6
Normal variation of the gut microbiota affects hepatic cytochrome P450 activity in mice	6
Chemogenetic activation of central gastrin‐releasing peptide‐expressing neurons elicits itch‐related scratching behavior in male and female mice	6
Protective effect of glycyrrhizin on coronary microembolization‐induced myocardial dysfunction in rats	6
Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium‐dependent, non‐D2 receptor‐dependent, manner	6
Effect of gastric acid‐reducing agents on the pharmacokinetics and efficacy of lemborexant	6

A novel step‐down infusion method of barbiturate therapy: Its safety and effectiveness for intracranial pressure control	6
SuperGAG biopolymers for treatment of excessive bladder permeability	6
Knockout of c‐Cbl slows EGFR endocytic trafficking and enhances EGFR signaling despite incompletely blocking receptor ubiquitylation	6
Increase in the risk of clopidogrel resistance and consequent TIMI flow impairment by DNA hypomethylation of CYP2C19 gene in STEMI patients undergoing primary percutaneous coronary intervention (PPCI)	6
Changes in clinical trials of endocrine disorder and metabolism and nutrition disorder drugs in mainland China over 2010–2019	6
Clinically relevant enantiomer specific R‐ and S‐praziquantel pharmacokinetic drug‐drug interactions with efavirenz and ritonavir	6
Effects of omecamtiv mecarbil on failing human ventricular trabeculae and interaction with (−)‐noradrenaline	6
The effect of substance P and its common in vivo‐formed metabolites on MRGPRX2 and human mast cell activation	6
Therapeutic approaches against coronaviruses acute respiratory syndrome	6
Inhibition of epigenetic reader proteins by apabetalone counters inflammation in activated innate immune cells from Fabry disease patients receiving enzyme replacement therapy	6
A physiologically based pharmacokinetic model of clopidogrel in populations of European and Japanese ancestry: An evaluation of CYP2C19 activity	6
A glutamate concentration‐biased allosteric modulator potentiates NMDA‐induced ion influx in neurons	6
Sensitivity of dose‐estimations for acute acetaminophen overdose in predicting hepatotoxicity risk using the Rumack‐Matthew Nomogram	6
Prevalence and determinants of attention deficit/hyperactivity disorder (ADHD) medication use during pregnancy: Results from the Quebec Pregnancy/Children Cohort	6
Analgesic effects of medicinal plants and phytochemicals on chemotherapy‐induced neuropathic pain through glial modulation	6
Fatty acids negatively regulate platelet function through formation of noncanonical 15‐lipoxygenase‐derived eicosanoids	5
Ivermectin synergizes sorafenib in hepatocellular carcinoma via targeting multiple oncogenic pathways	5
Repeated exposure of house dust mite induces progressive airway inflammation in mice: Differential roles of CCL17 and IL‐13	5
JP‐1366: A novel and potent potassium‐competitive acid blocker that is effective in the treatment of acid‐related diseases	5
Effect of mitoquinone on liver metabolism and steatosis in obese and diabetic rats	5
NR1I2 genetic polymorphisms and the risk of anti‐tuberculosis drug‐induced hepatotoxicity: A systematic review and meta‐analysis	5
Differential effects of glucose‐dependent insulinotropic polypeptide receptor/glucagon‐like peptide‐1 receptor heteromerization on cell signaling when expressed in HEK‐293 cells	5
Continuous effectiveness and safety after a hospital‐wide switch to adalimumab biosimilar: An observational study in rheumatoid arthritis patients	5
Utilization patterns and characteristics of users of biologic anti‐inflammatory agents in a large, US commercially insured population	5
Naringenin has an inhibitory effect on rivaroxaban in rats both in vitro and in vivo	5
Modulation of vascular contraction via soluble guanylate cyclase signaling in a novel ex vivo method using rat precision‐cut liver slices	5
Anticholinergic drugs and risk of dementia: Time for action?	5
Role of efficacy as a determinant of locomotor activation by mu‐opioid receptor (MOR) ligands in female and male mice. II. Effects of novel MOR‐selective phenylmorphan	5
Human organ chips for regenerative pharmacology	5
Healthcare costs and mortality associated with serious fluoroquinolone‐related adverse reactions	5
Massive presence of off‐label medicines in Danish neonatal departments: A nationwide survey using national hospital purchase data	5
Bufarenogin induces intrinsic apoptosis via Bax and ANT cooperation	5
Improvement of tissue‐specific distribution and biotransformation potential of nicotinamide mononucleotide in combination with ginsenosides or resveratrol	5
Polypharmacy and mortality association by chronic kidney disease status: The REasons for Geographic And Racial Differences in Stroke Study	5
Answering questions in a co‐created formative exam question bank improves summative exam performance, while students perceive benefits from answering, authoring, and peer discussion: A mixed methods a	5
The expression profile of platelet‐derived miRNA in coronary artery disease patients with clopidogrel resistance	5
A framework for economic evaluation of therapeutic drug monitoring—guided dosing in oncology	5
Tapentadol shows lower intrinsic efficacy at µ receptor than morphine and oxycodone	5
Metabolism of sumatriptan revisited	5
Suppression of collagen IV alpha‐2 subunit by prolyl hydroxylase domain inhibition via hypoxia‐inducible factor‐1 in chronic kidney disease	5
Fenofibrate in primary sclerosing cholangitis; a randomized, double‐blind, placebo‐controlled trial	5
Overall survival in metastatic melanoma correlates with pembrolizumab exposure and T cell exhaustion markers	5
Does atorvastatin therapy change the anti‐Xa activity in xabans‐treated patients with atrial fibrillation?	5
Are thyrotropin‐releasing hormone (TRH) and analog taltirelin viable reversal agents of opioid‐induced respiratory depression?	5
Gabapentin reduces painful bladder hypersensitivity in rats with lipopolysaccharide‐induced chronic cystitis	5
Human‐induced pluripotent stem cell‐derived cardiomyocytes: Cardiovascular properties and metabolism and pharmacokinetics of deuterated mexiletine analogs	4
Correlation between the drug concentration of polymyxin B and polymyxin B‐associated acute kidney injury in critically ill patients: A prospective study	4
Combined docking and machine learning identify key molecular determinants of ligand pharmacological activity on β2 adrenoceptor	4
Picotamide inhibits a wide spectrum of agonist‐induced smooth muscle contractions in porcine renal interlobar and coronary arteries	4
Pharmacokinetics, pharmacodynamics, and safety of verinurad with and without allopurinol in healthy Asian, Chinese, and non‐Asian participants	4
Why is motilin active in some studies with mice, rats, and guinea pigs, but not in others? Implications for functional variability among rodents	4
Effects of a recombinant humanized anti‐cocaine monoclonal antibody on the metabolism and distribution of cocaine in vitro and in mice	4
Efficacy and safety of dexmedetomidine in patients receiving mechanical ventilation: Evidence from randomized controlled trials	4
Mass balance and pharmacokinetics of an oral dose of 14C‐napabucasin in healthy adult male subjects	4
Rapamycin treatment increases survival, autophagy biomarkers and expression of the anti‐aging klotho protein in elderly mice	4
Antioxidant potential of chlorogenic acid in Age‐Related eye diseases	4
Cognitive and negative symptoms in schizophrenia with L‐Carnosine adjuvant therapy – A randomized double‐blind placebo‐controlled study	4
Tetramisole is a new IK1 channel agonist and exerts IK1‐dependent cardioprotective effects in rats	4
Is pitolisant safe for clinical use? A retrospective pharmacovigilance study focus on the post‐marketing safety	4
Morphine stimulates cervical cancer cells and alleviates cytotoxicity of chemotherapeutic drugs via opioid receptor‐dependent and ‐independent mechanisms	4
Oral antibiotics lower mycophenolate mofetil drug exposure, possibly by interfering with the enterohepatic recirculation: A case series	4
EOS789, pan‐phosphate transporter inhibitor, ameliorates the progression of kidney injury in anti‐GBM‐induced glomerulonephritis rats	4
Ocular safety of repeated intravitreal injections of Carboplatin and Digoxin: A preclinical study on the healthy rabbits	4
Exploring the kinetic selectivity of drugs targeting the β1‐adrenoceptor	4
Hypothesis: Amelioration of obesity‐induced cognitive dysfunction via a lorcaserin–betahistine combination treatment	4
Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant	4
Evaluation of the clinical cardiac safety of pemigatinib, a fibroblast growth factor receptor inhibitor, in participants with advanced malignancies	4
Phase 1 study of safety, pharmacokinetics, and antiviral activity of SARS‐CoV‐2 neutralizing monoclonal antibody ABBV‐47D11 in patients with COVID‐19	4
Adipose tissue‐derived stem cells as a potential candidate in treatment of Alzheimer's disease: A systematic review on preclinical studies	4
Impact of schizophrenia relapse definition on the comparative effectiveness of oral versus injectable antipsychotics: A systematic review and meta‐analysis of observational studies	4
Serious adverse drug reactions in sub‐Saharan Africa in the era of antiretroviral treatment: A systematic review	4
Quantification of BNN27, a novel neuroprotective 17‐spiroepoxy dehydroepiandrosterone derivative in the blood and retina of rodents, after single intraperitoneal administration	4
In vivo effects of AZD4547, a novel fibroblast growth factor receptor inhibitor, in a mouse model of endometriosis	4
Population pharmacokinetic of paracetamol and atorvastatin with co‐administration of semaglutide	4
Effects of a reactive oxygen species generator, napabucasin (BBI608), on tolerability, safety, pharmacokinetics, and QT/QTc interval in healthy volunteers	4
Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters	4
Real‐world efficacy and safety outcomes of imatinib treatment in patients with chronic myeloid leukemia: An Australian experience	4
Comparison of cardiac rehabilitation (exercise + education), exercise only, and usual care for patients with coronary artery disease: A non‐randomized retrospective analysis	4
Effects of dosing frequency on the clinical efficacy of ampicillin/sulbactam in Japanese elderly patients with pneumonia: A single‐center retrospective observational study	4
The efficacy of Jujube syrup on the prevention of drug‐induced hepatotoxicity in pulmonary tuberculosis patients: A pilot randomized double‐blind placebo‐controlled clinical trial	4
Donepezil improves vascular function in a mouse model of Alzheimer’s disease	4
Antiarrhythmic drug therapy after catheter ablation for atrial fibrillation—Insights from the German Ablation Registry	4
Mouse strain specificity of DAAO inhibitors‐mediated antinociception	4
A phase I, single‐center, open‐label study to investigate the absorption, distribution, metabolism and excretion of encorafenib following a single oral dose of 100 mg [14C] encor	4
Absorption, metabolism, and excretion of [14C]dersimelagon, an investigational oral selective melanocortin 1 receptor agonist, in preclinical species and healthy volunteers	4
TROIKA‐1: A double‐blind, randomized, parallel group, study aimed to demonstrate the equivalent pharmacokinetic profile of HD201, a potential biosimilar candidate to trastuzumab, versus EU‐Herceptin	3
Pharmacological hypothesis: A recombinant probiotic for taming bacterial β‐glucuronidase in drug‐induced enteropathy	3
The abrupt pathological deterioration of cisplatin‐induced acute kidney injury: Emerging of a critical time point	3
Markers of cholesterol synthesis to cholesterol absorption across the spectrum of non‐dialysis CKD: An observational study	3
Telmisartan and losartan: The marked differences between their chemical and pharmacological properties may explain the difference in therapeutic efficacy in hospitalized patients with COVID‐19	3
Computational design and molecular modeling of morphine derivatives for preferential binding in inflamed tissue	3
Modulation of TNF‐α, interleukin‐6, and interleukin‐10 by nebivolol–valsartan and nebivolol–lisinopril polytherapy in SHR rats	3
Safety, tolerability, and pharmacokinetics of single and multiple ascending Oral doses of DA‐8010 in healthy subjects: First‐in‐human phase I study	3
Bioequivalence and food effect of a fixed‐dose combination of macitentan and tadalafil: Adaptive design in the COVID‐19 pandemic	3
Evaluation of in vitro transdermal permeation, mass spectrometric imaging, and in vivo analgesic effects of pregabalin using a pluronic lecithin organogel formulation in mice	3