OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Intensive Care is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Long-term recovery of sensorimotor functions and prediction of participation in survivors of critical illness: a prospective cohort study	218
Mechanisms maintaining right ventricular contractility-to-pulmonary arterial elastance ratio in VA ECMO: a retrospective animal data analysis of RV–PA coupling	126
Diagnostic accuracy of tests for assessing readiness for liberation from mechanical ventilation in adults: an overview of reviews	80
Nutritional therapy for the prevention of post-intensive care syndrome	73
The revised recommendation for administering vitamin C in septic patients: the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020	70
Which factors are associated with acquired weakness in the ICU? An overview of systematic reviews and meta-analyses	60
Role of the interstitium during septic shock: a key to the understanding of fluid dynamics?	54
Dose–response relationship between transfusion and the incidence of infection in critically ill patients: a systematic review and dose–response meta-analysis	45
Long-term health outcomes of COVID-19 in ICU- and non-ICU-treated patients up to 2 years after hospitalization: a longitudinal cohort study (CO-FLOW)	36
Post-resuscitation diastolic blood pressure is a prognostic factor for outcomes of cardiac arrest patients: a multicenter retrospective registry-based analysis	33
External validation and comparative performance of the SLANT score for neuroprognostication in out-of-hospital cardiac arrest survivors undergoing targeted temperature management: insights from an Asi	31
Acute lung injury and post-cardiac arrest syndrome: a narrative review	31
Trends in massive transfusion practice for trauma in Japan from 2011 to 2020: a nationwide inpatient database study	31
Current corticosteroid therapeutic strategy for community-acquired pneumonia in adults: indications, dosage, and timing	31
Effects of a multicomponent sleep enhancement protocol on delirium incidence in elderly critically ill surgical patients: a randomized controlled trial	31
Analysis of urinary C–C motif chemokine ligand 14 (CCL14) and first-generation urinary biomarkers for predicting renal recovery from acute kidney injury: a prospective exploratory study	30
Extracorporeal membrane oxygenation for COVID-19-related acute respiratory distress syndrome: a narrative review	29
Management of endothelial dysfunction in septic shock: role of albumin administration	29
The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation	26
Calculated left ventricular outflow tract diameter for critically ill patients	26
Classifying diarrhea in critically ill patients through various criteria: a cohort study	24
Fentanyl as an induction agent for tracheal intubation in critically ill patients: a systematic review and meta-analysis	23
Clinical effectiveness of tigecycline in combination therapy against nosocomial pneumonia caused by CR-GNB in intensive care units: a retrospective multi-centre observational study	23
Early systemic insults following severe sepsis-associated encephalopathy of critically ill patients: association with mortality and awakening—an analysis of the OUTCOMEREA database	23
Acute pulmonary edema after subarachnoid hemorrhage: risk factors and comorbidities—an analysis of a nationwide database from the United States	22

Extracorporeal membrane oxygenation support for tropical infections: a scoping review	22
The hemodynamics of tracheal intubation in critically ill patients: a narrative review	21
The optimal glycemic target in critically ill patients: an updated network meta-analysis	21
Discontinuation of the development of remimazolam for ICU sedation in Japan: background and rationale	20
Circulating and urinary microRNAs profile for predicting renal recovery from severe acute kidney injury	20
Echocardiographic phenotypes in sepsis: identifying subgroups using latent profile analysis	19
Prognostic nutritional index as a predictive marker for acute kidney injury in adult critical illness population: a systematic review and diagnostic test accuracy meta-analysis	19
Long-term prognostic significance of gasping in out-of-hospital cardiac arrest patients undergoing extracorporeal cardiopulmonary resuscitation: a post hoc analysis of a multi-center prospective cohor	19
One-year outcomes in sepsis: a prospective multicenter cohort study in Japan	19
Thermal intervention improves pulse oximetry accuracy in critically ill patients with low perfusion: a quasi-experimental study	19
Low-flow time and outcomes in hypothermic cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation: a secondary analysis of a multi-center retrospective cohort study	18
Using laxative to recover intestinal function could improve the survival outcome for patients with cardiac arrest: a retrospective cohort study from MIMIC-IV database	18
Recent advances in cardiorespiratory monitoring in acute respiratory distress syndrome patients	17
Optimizing infection management after cardiac arrest: addressing diagnostic uncertainty and therapeutic dilemmas—a narrative review	16
Descriptive statistics and risk factor analysis of children with community-acquired septic shock	16
Post-intensive care syndrome follow-up system after hospital discharge: a narrative review	16
UNLOADERS-PVAD Weaning Score: predicting post-weaning adverse events in cardiogenic shock patients supported by microaxial flow pump	15
Correction: One-year outcomes in sepsis: a prospective multicenter cohort study in Japan	15
Exploring METRNL as a novel biomarker in sepsis: diagnostic potential and secretion mechanism	15
Association between antithrombin levels and prognosis in patients with sepsis: a retrospective cohort study based on the MIMIC-IV and MIMIC-III databases	14
Hemorrhage and thrombosis in COVID-19-patients supported with extracorporeal membrane oxygenation: an international study based on the COVID-19 critical care consortium	14
Impacts of three inspiratory muscle training programs on inspiratory muscles strength and endurance among intubated and mechanically ventilated patients with difficult weaning: a multicentre randomise	14
Strategies for discontinuing vasopressin and norepinephrine during the recovery phase of shock: a single-center retrospective study	13
The method to identify invasive mechanical ventilation with Japanese claim data	13
Construction of a predictive model and prognosis of left ventricular systolic dysfunction in patients with sepsis based on the diagnosis using left ventricular global longitudinal strain	13
Intensive care unit versus high-dependency care unit admission on mortality in patients with septic shock: a retrospective cohort study using Japanese claims data	13
Efficacy of permissive underfeeding for critically ill patients: an updated systematic review and trial sequential meta-analysis	13
Development and validation of a nomogram to predict the risk of sepsis-associated encephalopathy for septic patients in PICU: a multicenter retrospective cohort study	13
Autophagy and autophagic cell death in sepsis: friend or foe?	13
Prolonged use of neuromuscular blocking agents is associated with increased long-term mortality in mechanically ventilated medical ICU patients: a retrospective cohort study	12
PICS-SES postintensive care syndrome and socioeconomic status	12
Prone positioning in ARDS patients supported with VV ECMO, what we should explore?	12
Prediction of high-flow nasal cannula failure in critically ill patients: a narrative review	12
Changes in gene expression in healthcare workers during night shifts: implications for immune response and health risks	12
Longitudinal proteomic analysis of pathophysiology in plasma and bronchoalveolar lavage fluid of patients with ARDS	12
Impact of the COVID-19 pandemic on critical care utilization in Japan: a nationwide inpatient database study	12
Prognostic significance of delirium subtypes in critically ill medical and surgical patients: a secondary analysis of a prospective multicenter study	11
Association between the triglyceride–glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study	11
Effects of two ventilator-weaning methods on lung volume and ventilation distribution by electrical impedance tomography in post-cardiac surgery patients: a prospective cohort study	11
Re-evaluating albumin use in traumatic brain injury	11
External validation of 5A score model for predicting in-hospital mortality among the accidental hypothermia patients: JAAM-Hypothermia study 2018–2019 secondary analysis	11
Erythropoietin as a critical prognostic indicator in ICU patients with sepsis: a prospective observational study	11
Prognostic value of oxygen saturation index trajectory phenotypes on ICU mortality in mechanically ventilated patients: a multi-database retrospective cohort study	10
Onset timing and duration of augmented renal clearance in a mixed intensive care unit	10
Evaluating the diagnostic performance of adult sepsis event criteria in the emergency department: impact of including isolated serum lactate elevations	10
Association between the timing of ICU admission and mortality in patients with hospital-onset sepsis: a nationwide prospective cohort study	10
Hospital and regional variations in intensive care unit admission for patients with invasive mechanical ventilation	10
Occurrence of pendelluft during ventilator weaning with T piece correlated with increased mortality in difficult-to-wean patients	10
Rethinking diuretic use in acute kidney injury: effective prevention or false hope?	10
Effectiveness of systemic thrombolysis on clinical outcomes in high-risk pulmonary embolism patients with venoarterial extracorporeal membrane oxygenation: a nationwide inpatient database study	10

National cost of intensive care in Japan from 2018 to 2022	10
The cardioprotective and anti-inflammatory effect of inhaled nitric oxide during Fontan surgery in patients with single ventricle congenital heart defects: a prospective randomized study	10
Association of multiple sclerosis with mortality in sepsis: a population-level analysis	10
A pilot multicenter randomized controlled trial on individualized blood pressure targets versus standard care among critically ill patients with shock	9
Alteration of circulating redox balance in coronavirus disease-19-induced acute respiratory distress syndrome	9
Extracorporeal cardiopulmonary resuscitation with temperature management could improve the neurological outcomes of out-of-hospital cardiac arrest: a retrospective analysis of a nationwide multicenter	9
Prehospital tranexamic acid for trauma victims	9
Association of continuous renal replacement therapy downtime with fluid balance gap and clinical outcomes: a retrospective cohort analysis utilizing EHR and machine data	9
Combination of Cv-aCO2/Ca-vO2 and Pv-aCO2 as markers of resuscitation or microcirculation in patients with septic shock: a pilot study	9
Two-year trajectory of functional recovery and quality of life in post-intensive care syndrome: a multicenter prospective observational study on mechanically ventilated patients with coronavirus disea	8
Low apolipoprotein A-II levels causally contribute to increased mortality in septic shock	8
Computed tomography in ARDS, from morphological insights to AI-powered multi-modal analysis: a narrative review	8
Author’s response to the letter “Japanese clinical practice guidelines for rehabilitation in critically ill patients 2023 (J-ReCIP 2023)”	8
Different definitions of feeding intolerance and their associations with outcomes of critically ill adults receiving enteral nutrition: a systematic review and meta-analysis	8
Inhaled nitric oxide for acute respiratory distress syndrome in adults: a systematic review and meta-analysis	8
Hemoglobin in cardiogenic shock: the lower, the poorer survival	8
Optimal timing for assessing post-intensive care syndrome in clinical research: a scoping review and expert survey	7
Temporal trends of medical cost and cost-effectiveness in sepsis patients: a Japanese nationwide medical claims database	7
Efficacy of therapeutic drug monitoring-based antibiotic regimen in critically ill patients: a systematic review and meta-analysis of randomized controlled trials	7
Respiratory drive: a journey from health to disease	7
Increasing plasma calprotectin (S100A8/A9) is associated with 12-month mortality and unfavourable functional outcome in critically ill COVID-19 patients	7
Short- and long-term outcomes of elderly patients with acute kidney injury to acute kidney disease	7
Fundamental concepts and the latest evidence for esophageal pressure monitoring	7
Impact of sympathetic hyperactivity induced by brain microglial activation on organ damage in sepsis with chronic kidney disease	7
Pharmacological profiles and mechanism of action of remimazolam for ICU sedation	7
Visualizing the dynamic mechanical power and time burden of mechanical ventilation patients: an analysis of the MIMIC-IV database	7
Remimazolam in pediatric sedation and anesthesia: current perspectives and clinical considerations	7
Recovery of consciousness after acute brain injury: a narrative review	7
Prevention and management of critical care complications in cardiogenic shock: a narrative review	7
Effect of early intubation on patient-centered outcomes in urosepsis: a retrospective multicenter cohort study	6
Granulomonocytapheresis for chronic inflammatory diseases and sepsis	6
Long-term prevalence of PTSD symptom in family members of severe COVID-19 patients: a serial follow-up study extending to 18 months after ICU discharge	6
Exploring the scope of inspiratory muscle training in difficult weaning: reflections on the multicentre RCT	6
Mortality analysis among sepsis patients in and out of intensive care units using the Japanese nationwide medical claims database: a study by the Japan Sepsis Alliance study group	6
PEEP-AKI-COVID ICU: Effect of positive end-expiratory pressure on acute kidney injury development in patients with COVID-19-associated acute respiratory distress syndrome: an ancillary analysis of the	6
Comparison of balanced and unbalanced crystalloids as resuscitation fluid in patients treated for cardiogenic shock	6
Respiratory physiotherapy for critically ill children: concern regarding a recommendation	5
Japanese Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients 2023 (J-ReCIP 2023)	5
Long-term outcome of COVID-19 patients treated with helmet noninvasive ventilation vs. high-flow nasal oxygen: a randomized trial	5
Safety and efficacy of remimazolam in critical illness	5
Sepsis-related coagulopathy treatment based on the disseminated intravascular coagulation diagnostic criteria: a post-hoc analysis of a prospective multicenter observational study	5
Association between red blood cell distribution width and 30-day mortality in critically ill septic patients: a propensity score-matched study	5
Predictors of and hospital-level variation in intensive care unit readmissions in Japan: a nationwide inpatient database study	5
High driving pressure ventilation induces pulmonary hypertension in a rabbit model of acute lung injury	5
Impact of prehospital antibiotic therapy differs depending on septic shock origin	5
Ability of the respiratory ECMO survival prediction (RESP) score to predict survival for patients with COVID-19 ARDS and non-COVID-19 ARDS: a single-center retrospective study	5
Limitation of life sustaining measures in neurocritical care: sex, timing, and advance directive	5
Lacosamide dosing in patients receiving continuous renal replacement therapy	5
Normal saline versus Ringer’s solution and critical-illness mortality in acute pancreatitis: a nationwide inpatient database study	5
Outcomes of combined carbazochrome sodium sulfonate plus tranexamic acid therapy versus tranexamic acid monotherapy in traumatic brain injury: a retrospective cohort study in Japan	4
Critical evaluation of “Exploratory characterization of dynamic soluble programmed death-ligand 1 trajectories and their association with mortality in critical COVID-19”	4
Effects of normal saline versus lactated Ringer’s solution on organ function and inflammatory responses to heatstroke in rats	4
Clinical utility of diaphragmatic ultrasound for mechanical ventilator liberation in adults: a systematic review and meta-analysis	4
Prognostic implication of venoarterial extracorporeal membrane oxygenation in acute myocardial infarction-related cardiogenic shock	4
Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry	4
Association between initial intravenous fluid volume and the composite outcome of hemodialysis dependence at discharge or in-hospital mortality in inpatients with rhabdomyolysis	4
The impact of a preoperative nurse-led orientation program on postoperative delirium after cardiovascular surgery: a retrospective single-center observational study	4
Association between histological diaphragm atrophy and ultrasound diaphragm expiratory thickness in ventilated patients	4
The time cost of physiologically ineffective intravenous fluids in the emergency department: an observational pilot study employing wearable Doppler ultrasound	4
Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study	4
Concerns with the revised Japanese recommendation for administering vitamin C to septic patients	4
Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit	4
Unit-to-unit transfer due to shortage of intensive care beds in Sweden 2015–2019 was associated with a lower risk of death but a longer intensive care stay compared to no transfer: a registry study	4