OOIR: Observatory of International Research

Papers

(The TQCC of Gastroenterology Report is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Gastrointestinal cancers in China, the USA, and Europe	93
BRAF and KRAS mutations in metastatic colorectal cancer: future perspectives for personalized therapy	57
Anti-EGFR therapy in metastatic colorectal cancer: mechanisms and potential regimens of drug resistance	56
Role of gut microbiota in functional constipation	53
Phage-mediated horizontal gene transfer and its implications for the human gut microbiome	43
Tea polyphenol EGCG inhibited colorectal-cancer-cell proliferation and migration via downregulation of STAT3	38
Microbiome therapeutics: exploring the present scenario and challenges	33
Radiomics based on artificial intelligence in liver diseases: where are we?	29
Metabolic alterations and vulnerabilities in hepatocellular carcinoma	29
Upregulation of PD-L1 expression promotes epithelial-to-mesenchymal transition in sorafenib-resistant hepatocellular carcinoma cells	25
The influence of mitochondrial-directed regulation of Wnt signaling on tumorigenesis	22
lncRNA-PACER upregulates COX-2 and PGE2 through the NF-κB pathway to promote the proliferation and invasion of colorectal-cancer cells	22
Clinical characteristics and survival analysis of colorectal cancer in China: a retrospective cohort study with 13,328 patients from southern China	21
Cronkhite–Canada syndrome: from clinical features to treatment	19
Sodium butyrate protects against lipopolysaccharide-induced liver injury partially via the GPR43/ β-arrestin-2/NF-κB network	18
Genetic and epigenetic dependencies in colorectal cancer development	18
Influence of microbiota on immunity and immunotherapy for gastric and esophageal cancers	17
Skewed CD39/CD73/adenosine pathway contributes to B-cell hyperactivation and disease progression in patients with chronic hepatitis B	16
Convergent pathways of the gut microbiota–brain axis and neurodegenerative disorders	16
Therapeutic efficacy of ramucirumab after lenvatinib for post-progression treatment of unresectable hepatocellular carcinoma	15
Rewiring host–microbe interactions and barrier function during gastrointestinal inflammation	14
Interplays between drugs and the gut microbiome	14
Evaluating the safety and efficacy of mesenchymal stem cell-derived exosomes for treatment of refractory perianal fistula in IBD patients: clinical trial phase I	14
The tumor immune microenvironment transcriptomic subtypes of colorectal cancer for prognosis and development of precise immunotherapy	14
Acute hepatitis with autoimmune features after COVID-19 vaccine: coincidence or vaccine-induced phenomenon?	14

The response to vedolizumab in chronic granulomatous disease-related inflammatory bowel disease	13
Chromoendoscopy with targeted biopsies is superior to white-light endoscopy for the long-term follow-up detection of dysplasia in ulcerative colitis patients: a multicenter randomized–controlled trial	12
Intestinal microbiota research from a global perspective	12
Automatic anatomical classification of colonoscopic images using deep convolutional neural networks	11
One stomach, two subtypes of carcinoma—the differences between distal and proximal gastric cancer	11
Long-term outcome and prognostic factors of combined hepatocellular carcinoma and cholangiocarcinoma after curative resection	10
Post-operative prevention and monitoring of Crohn’s disease recurrence	9
Biologics: how far can they go in Crohn’s disease?	9
Clinical outcomes and gut microbiota analysis of severe alcohol-associated hepatitis patients undergoing healthy donor fecal transplant or pentoxifylline therapy: single-center experience from Kerala	9
Artificial intelligence in gastric cancer: applications and challenges	9
A predictive model for early recurrence of colorectal-cancer liver metastases based on clinical parameters	9
Risk factors for recurrence of colorectal conventional adenoma and serrated polyp	9
Elevated preoperative CA125 is associated with poor survival in patients with metastatic colorectal cancer undergoing primary tumor resection: a retrospective cohort study	8
Predictors of mortality and endoscopic intervention in patients with upper gastrointestinal bleeding in the intensive care unit	8
Review of Denonvilliers’ fascia: the controversies and consensuses	8
Diabetes mellitus type 2 drives metabolic reprogramming to promote pancreatic cancer growth	8
Transanal total mesorectal excision combined with intersphincteric resection has similar long-term oncological outcomes to laparoscopic abdominoperineal resection in low rectal cancer: a propensity sc	8
The association between disruption of the circadian rhythm and aggravation of colitis in mice	8
Chemoprevention of esophageal adenocarcinoma	7
Elevated peripheral blood neutrophil-to-lymphocyte ratio is associated with an immunosuppressive tumour microenvironment and decreased benefit of PD-1 antibody in advanced gastric cancer	7
Endoscopic ultrasound fine-needle biopsy vs fine-needle aspiration for lymph nodes tissue acquisition: a systematic review and meta-analysis	7
Comparing the clinical application values of the Degree of Ulcerative Colitis Burden of Luminal Inflammation (DUBLIN) score and Ulcerative Colitis Endoscopic Index of Severity (UCEIS) in patients with	7
Endoscopic pancreatic duct stenting for pain palliation in selected pancreatic cancer patients: a systematic review and meta-analysis	7
Strategies and recommendations for the management of gastrointestinal surgery during the COVID-19 pandemic: experience shared by Chinese surgeons	6
Hepatorenal syndrome in acute-on-chronic liver failure with acute kidney injury: more questions requiring discussion	6
Diagnostic performance of endoscopic ultrasound-guided tissue acquisition of splenic lesions: systematic review with pooled analysis	6
Key quality indicators in colonoscopy	6
Outcomes of a single-step endoscopic ultrasound-guided drainage of pancreatic-fluid collections using an electrocautery-enhanced coaxial lumen-apposing, self-expanding metal stent with and without flu	6
Genetic variants in promoter region of TFR2 is associated with the risk of non-alcoholic fatty liver disease in a Chinese Han population: a case–control study	6
A novel model for predicting fatty liver disease by means of an artificial neural network	6
NUDT15 genotyping during azathioprine treatment in patients with inflammatory bowel disease: implications for a dose-optimization strategy	5
An update on the management of non-variceal upper gastrointestinal bleeding	5
Endoscopic management of colorectal polyps	5
Genetic analysis of four consanguineous multiplex families with inflammatory bowel disease	5
Transanal vs laparoscopic total mesorectal excision for rectal cancer: a multicenter randomized phase III clinical trial (TaLaR trial) protocol	5
Eosinophilic pancreatitis: a review of the pathophysiology, diagnosis, and treatment	5
Renal-function change after transjugular intra-hepatic portosystemic shunt placement and its relationship with survival: a single-center experience	5
Is there a relationship between length of resection and lymph-node ratio in colorectal cancer?	5
Can a single-port robot be safely used for robotic total gastrectomy for advanced gastric cancer? First experience using the da Vinci SP platform	5
Culture and application of conditionally reprogrammed primary tumor cells	5
Multifaceted anti-colorectal tumor effect of digoxin on HCT8 and SW620 cells in vitro	5
Efficacy and safety of combined endoscopic cyanoacrylate injection and balloon-occluded retrograde transvenous occlusion (BRTOcc) of gastrorenal shunts in patients with bleeding gastric fundal varices	5
Visceral adipose volume is correlated with surgical tissue fibrosis in Crohn’s disease of the small bowel	4
Pregnancy and Crohn’s disease: concerns and assurance of medical therapy	4
Co-administration of ursodeoxycholic acid with rosuvastatin/ezetimibe in a non-alcoholic fatty liver disease model	4
Anatomy of the perirectal fascia at the level of rectosacral fascia revisited	4
A multicenter study assessing the prevalence of germline genetic alterations in Chinese gastric-cancer patients	4
Current management of gastro-oesophageal reflux disease—treatment costs, safety profile, and effectiveness: a narrative review	4
Predictors of lymph-node metastasis in surgically resected T1 colorectal cancer in Western populations	4
Laparoscopic radical right hemicolectomy with transrectal-specimen extraction: a novel natural-orifice specimen-extraction procedure	4

Superiority of urgent vs early endoscopic hemostasis in patients with upper gastrointestinal bleeding with high-risk stigmata	4
Transcriptomic biomarkers for predicting response to neoadjuvant treatment in oesophageal cancer	4
Artificial intelligence empowers the second-observer strategy for colonoscopy: a randomized clinical trial	4
Medically tailored meals for the management of symptomatic ascites: the SALTYFOOD pilot randomized clinical trial	4
Low ADAMTS-13/VWF ratio and altered gut–liver axis predict complications of advanced chronic liver disease: a pilot study	4
Upregulated insulin receptor tyrosine kinase substrate promotes the proliferation of colorectal cancer cells via the bFGF/AKT signaling pathway	4
The measurement and modification of hypoxia in colorectal cancer: overlooked but not forgotten	4
Density and distribution of lymphocytes in pretherapeutic rectal cancer and response to neoadjuvant therapy	4
Bariatric surgery proves long-term benefit in patients with cirrhosis	4
A risk-prediction score for colorectal lesions on 12,628 participants at high risk of colorectal cancer	4
Gastroesophageal reflux disease: recent innovations in endoscopic assessment and treatment	4
Hepatic sinusoidal obstruction syndrome due to tacrolimus in a liver-transplantation recipient	4
Remarkable response of BRAFV600E-mutated metastatic pancreatic cancer to BRAF/MEK inhibition: a case report	4
Surgery for Crohn’s disease: upfront or last resort?	4
Splenic-vasculature involvement is associated with poor prognosis in resected distal pancreatic cancer	4
State-of-the-art management of dysplastic Barrett's esophagus	4