Gastroenterology Report

Article	Citations
Gastrointestinal cancers in China, the USA, and Europe	93
BRAF and KRAS mutations in metastatic colorectal cancer: future perspectives for personalized therapy	57
Anti-EGFR therapy in metastatic colorectal cancer: mechanisms and potential regimens of drug resistance	56
Role of gut microbiota in functional constipation	53
Phage-mediated horizontal gene transfer and its implications for the human gut microbiome	43
Tea polyphenol EGCG inhibited colorectal-cancer-cell proliferation and migration via downregulation of STAT3	38
Microbiome therapeutics: exploring the present scenario and challenges	33
Radiomics based on artificial intelligence in liver diseases: where are we?	29
Metabolic alterations and vulnerabilities in hepatocellular carcinoma	29
Upregulation of PD-L1 expression promotes epithelial-to-mesenchymal transition in sorafenib-resistant hepatocellular carcinoma cells	25
The influence of mitochondrial-directed regulation of Wnt signaling on tumorigenesis	22
lncRNA-PACER upregulates COX-2 and PGE2 through the NF-κB pathway to promote the proliferation and invasion of colorectal-cancer cells	22
Clinical characteristics and survival analysis of colorectal cancer in China: a retrospective cohort study with 13,328 patients from southern China	21
Cronkhite–Canada syndrome: from clinical features to treatment	19
Sodium butyrate protects against lipopolysaccharide-induced liver injury partially via the GPR43/ β-arrestin-2/NF-κB network	18
Genetic and epigenetic dependencies in colorectal cancer development	18
Influence of microbiota on immunity and immunotherapy for gastric and esophageal cancers	17
Skewed CD39/CD73/adenosine pathway contributes to B-cell hyperactivation and disease progression in patients with chronic hepatitis B	16
Convergent pathways of the gut microbiota–brain axis and neurodegenerative disorders	16
Therapeutic efficacy of ramucirumab after lenvatinib for post-progression treatment of unresectable hepatocellular carcinoma	15
Rewiring host–microbe interactions and barrier function during gastrointestinal inflammation	14
Interplays between drugs and the gut microbiome	14
Evaluating the safety and efficacy of mesenchymal stem cell-derived exosomes for treatment of refractory perianal fistula in IBD patients: clinical trial phase I	14
The tumor immune microenvironment transcriptomic subtypes of colorectal cancer for prognosis and development of precise immunotherapy	14
Acute hepatitis with autoimmune features after COVID-19 vaccine: coincidence or vaccine-induced phenomenon?	14

The response to vedolizumab in chronic granulomatous disease-related inflammatory bowel disease	13
Chromoendoscopy with targeted biopsies is superior to white-light endoscopy for the long-term follow-up detection of dysplasia in ulcerative colitis patients: a multicenter randomized–controlled trial	12
Intestinal microbiota research from a global perspective	12
Automatic anatomical classification of colonoscopic images using deep convolutional neural networks	11
One stomach, two subtypes of carcinoma—the differences between distal and proximal gastric cancer	11
Long-term outcome and prognostic factors of combined hepatocellular carcinoma and cholangiocarcinoma after curative resection	10
Post-operative prevention and monitoring of Crohn’s disease recurrence	9
Biologics: how far can they go in Crohn’s disease?	9
Clinical outcomes and gut microbiota analysis of severe alcohol-associated hepatitis patients undergoing healthy donor fecal transplant or pentoxifylline therapy: single-center experience from Kerala	9
Artificial intelligence in gastric cancer: applications and challenges	9
A predictive model for early recurrence of colorectal-cancer liver metastases based on clinical parameters	9
Risk factors for recurrence of colorectal conventional adenoma and serrated polyp	9
Elevated preoperative CA125 is associated with poor survival in patients with metastatic colorectal cancer undergoing primary tumor resection: a retrospective cohort study	8
Predictors of mortality and endoscopic intervention in patients with upper gastrointestinal bleeding in the intensive care unit	8
Review of Denonvilliers’ fascia: the controversies and consensuses	8
Diabetes mellitus type 2 drives metabolic reprogramming to promote pancreatic cancer growth	8
Transanal total mesorectal excision combined with intersphincteric resection has similar long-term oncological outcomes to laparoscopic abdominoperineal resection in low rectal cancer: a propensity sc	8
The association between disruption of the circadian rhythm and aggravation of colitis in mice	8
Chemoprevention of esophageal adenocarcinoma	7
Elevated peripheral blood neutrophil-to-lymphocyte ratio is associated with an immunosuppressive tumour microenvironment and decreased benefit of PD-1 antibody in advanced gastric cancer	7
Endoscopic ultrasound fine-needle biopsy vs fine-needle aspiration for lymph nodes tissue acquisition: a systematic review and meta-analysis	7
Comparing the clinical application values of the Degree of Ulcerative Colitis Burden of Luminal Inflammation (DUBLIN) score and Ulcerative Colitis Endoscopic Index of Severity (UCEIS) in patients with	7
Endoscopic pancreatic duct stenting for pain palliation in selected pancreatic cancer patients: a systematic review and meta-analysis	7
Strategies and recommendations for the management of gastrointestinal surgery during the COVID-19 pandemic: experience shared by Chinese surgeons	6
Hepatorenal syndrome in acute-on-chronic liver failure with acute kidney injury: more questions requiring discussion	6
Diagnostic performance of endoscopic ultrasound-guided tissue acquisition of splenic lesions: systematic review with pooled analysis	6
Key quality indicators in colonoscopy	6
Outcomes of a single-step endoscopic ultrasound-guided drainage of pancreatic-fluid collections using an electrocautery-enhanced coaxial lumen-apposing, self-expanding metal stent with and without flu	6
Genetic variants in promoter region of TFR2 is associated with the risk of non-alcoholic fatty liver disease in a Chinese Han population: a case–control study	6
A novel model for predicting fatty liver disease by means of an artificial neural network	6
NUDT15 genotyping during azathioprine treatment in patients with inflammatory bowel disease: implications for a dose-optimization strategy	5
An update on the management of non-variceal upper gastrointestinal bleeding	5
Endoscopic management of colorectal polyps	5
Genetic analysis of four consanguineous multiplex families with inflammatory bowel disease	5
Transanal vs laparoscopic total mesorectal excision for rectal cancer: a multicenter randomized phase III clinical trial (TaLaR trial) protocol	5
Eosinophilic pancreatitis: a review of the pathophysiology, diagnosis, and treatment	5
Renal-function change after transjugular intra-hepatic portosystemic shunt placement and its relationship with survival: a single-center experience	5
Is there a relationship between length of resection and lymph-node ratio in colorectal cancer?	5
Can a single-port robot be safely used for robotic total gastrectomy for advanced gastric cancer? First experience using the da Vinci SP platform	5
Culture and application of conditionally reprogrammed primary tumor cells	5
Multifaceted anti-colorectal tumor effect of digoxin on HCT8 and SW620 cells in vitro	5
Efficacy and safety of combined endoscopic cyanoacrylate injection and balloon-occluded retrograde transvenous occlusion (BRTOcc) of gastrorenal shunts in patients with bleeding gastric fundal varices	5
Hepatic sinusoidal obstruction syndrome due to tacrolimus in a liver-transplantation recipient	4
Visceral adipose volume is correlated with surgical tissue fibrosis in Crohn’s disease of the small bowel	4
Pregnancy and Crohn’s disease: concerns and assurance of medical therapy	4
Anatomy of the perirectal fascia at the level of rectosacral fascia revisited	4
A multicenter study assessing the prevalence of germline genetic alterations in Chinese gastric-cancer patients	4
Current management of gastro-oesophageal reflux disease—treatment costs, safety profile, and effectiveness: a narrative review	4
Predictors of lymph-node metastasis in surgically resected T1 colorectal cancer in Western populations	4
Co-administration of ursodeoxycholic acid with rosuvastatin/ezetimibe in a non-alcoholic fatty liver disease model	4

Laparoscopic radical right hemicolectomy with transrectal-specimen extraction: a novel natural-orifice specimen-extraction procedure	4
Superiority of urgent vs early endoscopic hemostasis in patients with upper gastrointestinal bleeding with high-risk stigmata	4
Transcriptomic biomarkers for predicting response to neoadjuvant treatment in oesophageal cancer	4
Artificial intelligence empowers the second-observer strategy for colonoscopy: a randomized clinical trial	4
Low ADAMTS-13/VWF ratio and altered gut–liver axis predict complications of advanced chronic liver disease: a pilot study	4
Upregulated insulin receptor tyrosine kinase substrate promotes the proliferation of colorectal cancer cells via the bFGF/AKT signaling pathway	4
The measurement and modification of hypoxia in colorectal cancer: overlooked but not forgotten	4
Density and distribution of lymphocytes in pretherapeutic rectal cancer and response to neoadjuvant therapy	4
Medically tailored meals for the management of symptomatic ascites: the SALTYFOOD pilot randomized clinical trial	4
Bariatric surgery proves long-term benefit in patients with cirrhosis	4
A risk-prediction score for colorectal lesions on 12,628 participants at high risk of colorectal cancer	4
Gastroesophageal reflux disease: recent innovations in endoscopic assessment and treatment	4
Remarkable response of BRAFV600E-mutated metastatic pancreatic cancer to BRAF/MEK inhibition: a case report	4
Surgery for Crohn’s disease: upfront or last resort?	4
Splenic-vasculature involvement is associated with poor prognosis in resected distal pancreatic cancer	4
State-of-the-art management of dysplastic Barrett's esophagus	4
Redo pull-through in total colonic aganglionosis due to residual aganglionosis: a single center’s experience	3
Knife-assisted resection (KAR) for small rectal neuroendocrine neoplasia	3
Usefulness of tumor traction with a snare and endoclips in gastric submucosal tumor resection: a propensity-score-matching analysis	3
Identification of immune cell infiltration landscape for predicting prognosis of colorectal cancer	3
Survival outcomes following laparoscopic vs open surgery for non-metastatic rectal cancer: a two-center cohort study with propensity score matching	3
Acute pancreatitis as a clinical presentation of COVID-19 in a patient with HIV infection: a case report	3
Third-space endoscopy: the final frontier	3
A new radiomics approach combining the tumor and peri-tumor regions to predict lymph node metastasis and prognosis in gastric cancer	3
Oral vancomycin in the treatment of primary sclerosing cholangitis-associated pouchitis	3
An 11-gene signature for the prediction of systemic recurrences in colon adenocarcinoma	3
Gunsight sutures significantly reduce surgical-site infection after ileostomy reversal compared with linear sutures	3
Impact of intestinal ultrasound with a portable system in the management of Crohn’s disease	3
Low prevalence of mismatch repair deficiency in Chinese colorectal cancers: a multicenter study	3
Values of a novel pyroptosis-related genetic signature in predicting outcome and immune status of pancreatic ductal adenocarcinoma	3
Nomogram to predict primary non-response to infliximab in patients with Crohn’s disease: a multicenter study	3
Programmed death-ligand 1 expression in the tumour stroma of colorectal liver oligometastases and its association with prognosis after liver resection	3
How likely is septic shock to develop in a patient with Fournier's gangrene? A risk prediction model based on a 7-year retrospective study	3
Total neoadjuvant treatment for MRI-stratified high-risk rectal cancer: a single-center, single-arm, prospective Phase II trial (PKUCH-R02)	3
Comparison of guidelines on rectal cancer: exception proves the rule?	3
Robotic total gastrectomy for carcinoma in the remnant stomach: a comparison with laparoscopic total gastrectomy	3
National trends and outcomes of genetically inherited non-alcoholic chronic liver disease in the USA: estimates from the National Inpatient Sample (NIS) database	3
Serum exosomal microRNA-144-3p: a promising biomarker for monitoring Crohn's disease	3
Can transcutaneous perianal ultrasonography be the first-line diagnostic instrument for evaluating pediatric perianal fistulas?	3
Development and validation of a nomogram to predict indolent course in patients with ulcerative colitis: a single-center retrospective study	3
Efficacy and safety of low-dose thalidomide combined with mesalazine in the treatment of refractory ulcerative colitis in adults	3
Multi-frequency magnetic resonance elastography of the pancreas: measurement reproducibility and variance among healthy volunteers	3
Current trends in access to treatment for hepatitis B in immigrants vs non-immigrants	3
Nomogram for predicting overall survival time of patients with stage IV colorectal cancer	3
Immunomodulators: still having a role?	3
External rectal prolapse: abdominal or perineal repair for men? A retrospective cohort study	2
The presence and outcome of biliary sphincter disorders in liver-transplant recipients according to the Rome IV classification	2
Evolution of interventional endoscopic ultrasound	2
Learning curves of resection and reconstruction procedures in robotic-assisted pancreatoduodenectomy by a single surgeon: a retrospective cohort study of 160 consecutive cases	2
Evaluation of the risk factors for severe complications and surgery of intestinal foreign bodies in adults: a single-center experience with 180 cases	2
Psychosocio-economic impacts of COVID-19 on gastroenterology and endoscopy practice	2
Predicted pro-inflammatory hs-CRP score and non-alcoholic fatty liver disease	2
Laparoscopic gastrectomy for elderly gastric-cancer patients: comparisons with laparoscopic gastrectomy in non-elderly patients and open gastrectomy in the elderly	2
Incidence and risk of herpes zoster in patients with ulcerative colitis and Crohn’s disease in the USA	2
A rare case of epiploic appendagitis in a patient affected by ulcerative colitis on vedolizumab therapy	2
Endoscopic band ligation with hypertonic glucose cushion in the treatment of ileal pouch prolapse	2
Hepatic arterial infusion of oxaliplatin plus raltitrexed in unresectable hepatocellular carcinoma with or without portal vein tumour thrombosis	2
Classification and genetic counselling for a novel splicing mutation of the MLH1 intron associated with Lynch syndrome in colorectal cancer	2
Exploration of the shared gene signatures and molecular mechanisms between periodontitis and inflammatory bowel disease: evidence from transcriptome data	2
Characteristics of superficial esophageal squamous cell carcinomas undetectable with narrow-band imaging endoscopy	2
A case of COVID-19 complicated by massive gastrointestinal bleeding	2
The molecular pathogenesis of achalasia: a paired lower esophageal sphincter muscle and serum 4D label-free proteomic study	2
The “Chinese Expert Consensus on the Clinical Application of the Chinese Modified Triplet Combination with Irinotecan (CPT-11), Oxaliplatin (LOHP), Continuous Infusion 5-Fluorouracil, and Leucovorin f	2
Intensity-specific considerations for exercise for patients with inflammatory bowel disease	2
Predictors of mortality in patients with acute small-bowel perforation transferred to ICU after emergency surgery: a single-centre retrospective cohort study	2
A challenging case of alpha-fetoprotein-result discrepancies in a patient with chronic hepatitis B	2
Development of a narrow-band imaging classification to reduce the need for routine biopsies of gastric polyps	2
Gallbladder bleeding along with cholecystocolonic fistula: a case report	2
Re-recognition of BMPR1A-related polyposis: beyond juvenile polyposis and hereditary mixed polyposis syndrome	2
A rare case of omental extra-gastrointestinal stromal tumor showing two coexisting mutations on exon 14 of the PDGFRA gene	2
The 96-week clinical outcomes after cessation of nucleos(t)ide analog treatment in chronic hepatitis B patients	2
Development and validation of novel models for the prediction of intravenous corticosteroid resistance in acute severe ulcerative colitis using logistic regression and machine learning	2
Improved hepatitis A and hepatitis B vaccination strategy is necessary for patients with chronic hepatitis C	2
Cut-off value of ulcerative colitis endoscopic index of severity (UCEIS) score for predicting the need for pouch construction in ulcerative colitis: results of a multicenter study with long-term follo	2
The six-question Gastroesophageal Reflux Disease Questionnaire (GerdQ) cannot accurately quantify reflux and reflux-associated symptoms frequency	2
Interventional inflammatory bowel disease: endoscopic therapy of complications of Crohn’s disease	2
Is the transperineal ultrasonography approach effective for the diagnosis of rectocele?	1
Multicenter prospective validation study of the SAFE-T colonoscopy evaluation tool: a web-based smartphone application for evaluation of gastroenterology fellow performance in colonoscopy	1
First preclinical experience with the newly developed EDGE SP1000 single-port robotic surgical system-assisted transanal total mesorectal excision	1
An esophageal submucosal tumor treated with submucosal tunneling endoscopic resection: an unexpected result	1

Targeting KRAS G12C mutations in colorectal cancer	1
Evolving treatment strategies in Crohn’s disease	1
The dilemma of cytomegalovirus and hepatitis B virus interaction	1
Sharp recanalization using Chiba biopsy needle for the treatment of biliary occlusion after radiofrequency ablation	1
Diagnostic performance of elastography on liver fibrosis in antiviral treatment-naive chronic hepatitis B patients: a meta-analysis	1
Berberine alleviates non-alcoholic hepatic steatosis partially by promoting SIRT1 deacetylation of CPT1A in mice	1
Post hoc validation of a tool that accurately predicts the outcome of endoscopic therapy in Bouveret syndrome	1
Risk factors and clinical outcomes of incomplete endoscopic resection of small rectal neuroendocrine tumors in southern China: a 9-year data analysis	1
Effect of Wuda granule on gastrointestinal function recovery after laparoscopic intestinal resection: a randomized–controlled trial	1
Values of spleen-preserving distal pancreatectomy in well-differentiated non-functioning pancreatic neuroendocrine tumors: a comparative study	1
RIFLE: a Phase II trial of stereotactic ablative radiotherapy combined with fruquintinib and tislelizumab in metastatic colorectal cancer	1
Tackling clinical complexity: how inpatient subspecialty gastroenterology services enhance patient care	1
Regular diet is non-inferior to restricted diet after polypectomy with decreased hospitalization length of stay and cost: a randomized–controlled trial	1
Redeploying gastroenterologists during the COVID-19 pandemic: early experience with telehealth including clinical access and financial implications	1
Device-assisted enteroscopy-based stricturotomy for small bowel strictures associated with Crohn’s disease (with video)	1
Liver collision lesion: inflammatory hepatocellular adenoma within focal nodular hyperplasia	1
Editorial of special issue on pharmacotherapeutics of digestive tumors	1
Submucosal tunneling endoscopic biopsy and myotomy for management of unknown esophageal stenosis	1
Advances in endobariatrics: past, present, and future	1
The HARBINGER of endoscopic therapy in critically-ill patients with upper GI bleeding	1
Vascular reconstruction of segmental intestinal grafts using autologous internal iliac vessels	1
Stem cell therapy: light in the tunnel for penetrating Crohn's disease	1
Rectal-cancer radiotherapy damages the perineal muscle floor	1
Lymphocyte-to-monocyte ratio is a short-term predictive marker of ulcerative colitis after induction of advanced therapy	1
Higher risk of neoplastic progression of Barrett’s esophagus in patients with systemic sclerosis	1
Liver-specific deficiency of TMEM30A develops spontaneous hepatocellular carcinoma	1
Small-cell neuroendocrine carcinoma arising from an extra-hepatic bile duct: a case report	1
Severe rectal burn induced by hot normal saline enema: a case report	1
The SAFE-T upper endoscopy tool: a web-based application for the point-of-care evaluation of gastroenterology fellow performance in upper endoscopy	1
Pyloric-gland metaplasia may be an origin of cancer and intestinal metaplasia with possible CDX2 expression	1
Treatment of colonic varices with a superior mesenteric venous stent: a case report describing a unique approach	1
A novel transperineal approach for surgical resection of presacral tumors with an arc-shaped incision in front of the apex of the coccyx (with video)	1
Antibiotic prophylaxis and infectious complications in patients on peritoneal dialysis undergoing lower gastrointestinal endoscopy	1
Insights into the underlying mechanisms and clinical management of microscopic colitis in relation to other gastrointestinal disorders	1
Unveiling mitophagy-mediated molecular heterogeneity and development of a risk signature model for colorectal cancer by integrated scRNA-seq and bulk RNA-seq analysis	1
Non-invasive digestion monitoring with an FDA-cleared wearable biosensor: further validation for use in tracking food ingestion	1
The relationship between zinc deficiency and infectious complications in patients with hepatitis B virus-related acute-on-chronic liver failure	1
The role of computer-assisted systems for upper-endoscopy quality monitoring and assessment of gastric lesions	1
When evidence is lacking: a mixed-methods approach for the development of practice guidance in liver transplantation	1
An exclusive fine-needle biopsy approach to sampling solid lesions under EUS guidance: a prospective cohort study	1
Enterocolic phlebitis: a rare cause of bowel ischemia and review of the literature	1
The efficacy and safety of thalidomide in the treatment of refractory Crohn's disease in adults: a double-center, double-blind, randomized–controlled trial	1
Primary malignant tumours and malignant transformation of cysts in the retrorectal space: MRI diagnosis and treatment outcomes	1
Escherichia coli O157: H7 sepsis following fecal microbiota transplant in an IgA-deficient inflammatory bowel disease patient	1
Post-operative anastomotic leakage and collagen changes in patients with rectal cancer undergoing neoadjuvant chemotherapy vs chemoradiotherapy	1
Endoscopic management of delayed bleeding after polypectomy of small colorectal polyps: two or more clips may be safe	1
A mysterious cause of recurrent acute liver dysfunction for over a decade	1
Is there a standardized practice for the development of international ulcerative colitis and Crohn’s disease treatment guidelines?	1
Outcomes of a modified Bresler procedure for the treatment of rectocele with rectal intussusception	1
Natural history, clinical characteristics, outcomes, and long-term follow-up of pain-free chronic pancreatitis	1
Endo-anesthesia: a primer	1
Dynamic heterogeneity of colorectal cancer during progression revealed clinical risk-associated cell types and regulations in single-cell resolution and spatial context	1
Avoidance of urinary drainage during perioperative period of open elective colonic resection within enhanced recovery after surgery programme	1