Acta Neuropathologica Communications

Article	Citations
Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche	135
Dual-probe fluorescence spectroscopy for sensitive quantitation of Alzheimer’s amyloid pathology	122
Immunological and tumor-intrinsic mechanisms mediate the synergistic growth suppression of experimental glioblastoma by radiotherapy and MET inhibition	113
Axonal autophagic vesicle transport in the rat optic nerve in vivo under normal conditions and during acute axonal degeneration	111
Dissection of transcriptomic and epigenetic heterogeneity of grade 4 gliomas: implications for prognosis	108
Correction: Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems	104
A novel case of glial transdifferentiation in renal medullary carcinoma brain metastasis	100
The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration	95
Hyperspectral retinal imaging in Alzheimer’s disease and age-related macular degeneration: a review	81
Asymmetric dysregulation of glutamate dynamics across the synaptic cleft in a mouse model of Alzheimer’s disease	74
The inflammatory pathology of dysferlinopathy is distinct from calpainopathy, Becker muscular dystrophy, and inflammatory myopathies	74
Astrocytes respond to a neurotoxic Aβ fragment with state-dependent Ca2+ alteration and multiphasic transmitter release	62
Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease	59
A novel BRAF::PTPRN2 fusion in meningioma: a case report	59
Potential prognostic determinants for FET::CREB fusion-positive intracranial mesenchymal tumor	56
Protein farnesylation is upregulated in Alzheimer’s human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer’s model mice	53
Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses	53
NRF2/ARE mediated antioxidant response to glaucoma: role of glia and retinal ganglion cells	52
Prion strains associated with iatrogenic CJD in French and UK human growth hormone recipients	51
Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis	50
Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies	47
Focal amyloid and asymmetric tau in an imaging-to-autopsy case of clinical primary progressive aphasia with Alzheimer disease neuropathology	47
Early biomarkers in the presymptomatic phase of cognitive impairment: changes in the endocannabinoidome and serotonergic pathways in Alzheimer's-prone mice after mTBI	45
Two distinct conformers of PrPD type 1 of sporadic Creutzfeldt–Jakob disease with codon 129VV genotype faithfully propagate in vivo	42
The genomic alterations in glioblastoma influence the levels of CSF metabolites	41

Oligodendrocyte lineage is severely affected in human alcohol-exposed foetuses	41
NAD salvage pathway machinery expression in normal and glaucomatous retina and optic nerve	40
Pleomorphic xanthoastrocytoma in the multiverse of epigenomics: is it time to recognize the variants?	39
Cortical microvascular raspberries and ageing: an independent but not exclusive relationship	39
Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer’s Disease	38
The neuropathological landscape of small vessel disease and Lewy pathology in a cohort of Hispanic and non-Hispanic White decedents with Alzheimer disease	38
Deep histopathology genotype–phenotype analysis of focal cortical dysplasia type II differentiates between the GATOR1-altered autophagocytic subtype IIa and MTOR-altered migration deficient subtype II	38
Clinicopathologic features of two unrelated autopsied patients with Charcot-Marie-Tooth disease carrying MFN2 gene mutation	38
Alterations in iron content, iron-regulatory proteins and behaviour without tau pathology at one year following repetitive mild traumatic brain injury	37
A pathogenic mutation in the ALS/FTD gene VCP induces mitochondrial hypermetabolism by modulating the permeability transition pore	37
Response to the letter by de Boer et al. (2022)	36
Pathological changes induced by Alzheimer’s brain inoculation in amyloid-beta plaque-bearing mice	36
Development and characterization of novel anti-acetylated tau monoclonal antibodies to probe pathogenic tau species in Alzheimer’s disease	36
Severe ACTA1-related nemaline myopathy: intranuclear rods, cytoplasmic bodies, and enlarged perinuclear space as characteristic pathological features on muscle biopsies	35
Genetic ablation of Sarm1 attenuates expression and mislocalization of phosphorylated TDP-43 after mouse repetitive traumatic brain injury	35
Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas	35
Tuberous sclerosis complex is a novel, amyloid-independent tauopathy associated with elevated phosphorylated 3R/4R tau aggregation	35
Three dimensional evaluation of cerebrovascular density and branching in chronic traumatic encephalopathy	34
Novel histotypes of sporadic Creutzfeldt–Jakob disease linked to 129MV genotype	34
Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo	34
Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA-NCOA1/2 fusions	33
Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains	32
Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice	31
The polyG diseases: a new disease entity	31
Loss of Sarm1 reduces retinal ganglion cell loss in chronic glaucoma	31
Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer’s disease	30
Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases ε and δ in glioma families	30
Distinct tumor-TAM interactions in IDH-stratified glioma microenvironments unveiled by single-cell and spatial transcriptomics	30
The degree of astrocyte activation is predictive of the incubation time to prion disease	30
Interpretable deep learning of myelin histopathology in age-related cognitive impairment	29
Importance of extracellular vesicle secretion at the blood–cerebrospinal fluid interface in the pathogenesis of Alzheimer’s disease	29
Neutrophils predominate the immune signature of cerebral thrombi in COVID-19 stroke patients	29
Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease	29
Unsupervised machine learning identifies distinct ALS molecular subtypes in post-mortem motor cortex and blood expression data	29
A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas	29
Antemortem detection of Parkinson’s disease pathology in peripheral biopsies using artificial intelligence	28
Transmission of amyloid-beta and tau pathologies is associated with cognitive impairments in a primate	28
Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures	28
Spatial progression and molecular heterogeneity of IDH-mutant glioblastoma determined by DNA methylation-based mapping	28
Heparanase overexpression impedes perivascular clearance of amyloid-β from murine brain: relevance to Alzheimer’s disease	28
DNA hypomethylator phenotype reprograms glutamatergic network in receptor tyrosine kinase gene-mutated glioblastoma	28
Disease and brain region specific immune response profiles in neurodegenerative diseases with pure and mixed protein pathologies	27
Machine learning quantification of Amyloid-β deposits in the temporal lobe of 131 brain bank cases	27
TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6	27
3-Dimensional morphological characterization of neuroretinal microglia in Alzheimer’s disease via machine learning	27
Early inner plexiform layer thinning and retinal nerve fiber layer thickening in excitotoxic retinal injury using deep learning-assisted optical coherence tomography	27
Efficacy of BRAF/MEK-inhibitor therapy for epithelioid glioblastoma with a novel BRAFV600 mutation	27
Repetitive mild traumatic brain injury in mice triggers a slowly developing cascade of long-term and persistent behavioral deficits and pathological changes	27
A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons	27
Bruton’s tyrosine kinase inhibition reduces disease severity in a model of secondary progressive autoimmune demyelination	27

Molecular pathology, developmental changes and synaptic dysfunction in (pre-) symptomatic human C9ORF72-ALS/FTD cerebral organoids	26
Trem2-deficiency aggravates and accelerates age-related myelin degeneration	26
Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia	26
MGMT methylation pattern of long-term and short-term survivors of glioblastoma reveals CpGs of the enhancer region to be of high prognostic value	26
SARS-Cov-2 infection and neuropathological findings: a report of 18 cases and review of the literature	25
Beyond genetics: including the environmental dimension in amyloidosis mouse models for Alzheimer’s disease	25
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies	25
Different MAPT haplotypes influence expression of total MAPT in postmortem brain tissue	25
MiR-212-3p functions as a tumor suppressor gene in group 3 medulloblastoma via targeting nuclear factor I/B (NFIB)	24
White matter injury but not germinal matrix hemorrhage induces elevated osteopontin expression in human preterm brains	24
A recurrent RYR1 mutation associated with early-onset hypotonia and benign disease course	24
Widespread retina and optic nerve neuroinflammation in enucleated eyes from glaucoma patients	24
Histone acetylation in an Alzheimer’s disease cell model promotes homeostatic amyloid-reducing pathways	24
The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS	23
Accurate digital quantification of tau pathology in progressive supranuclear palsy	23
Single-cell spatial proteomic imaging for human neuropathology	23
BDNF-dependent modulation of axonal transport is selectively impaired in ALS	23
Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS	23
Clinico-pathological and epigenetic heterogeneity of diffuse gliomas with FGFR3::TACC3 fusion	23
Neuropathology-based approach reveals novel Alzheimer's Disease genes and highlights female-specific pathways and causal links to disrupted lipid metabolism: insights into a vicious cycle	23
TwinF interface inhibitor FP802 prevents retinal ganglion cell loss in a mouse model of amyotrophic lateral sclerosis	23
C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer’s disease	22
The neuropathologic findings in a case of progressive cavitating leukoencephalopathy due to NDUFV1 pathogenic variants	22
Exogenous interleukin 33 enhances the brain’s lymphatic drainage and toxic protein clearance in acute traumatic brain injury mice	22
Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study	21
Ultrasensitive tau biosensor cells detect no seeding in Alzheimer’s disease CSF	21
Low-intensity open-field blast exposure effects on neurovascular unit ultrastructure in mice	21
Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling	21
Tau seeding in cases of multiple sclerosis	20
Human post-mortem organotypic brain slice cultures: a tool to study pathomechanisms and test therapies	20
Downstream effects of polypathology on neurodegeneration of medial temporal lobe subregions	20
Right temporal variant frontotemporal dementia is pathologically heterogeneous: a case-series and a systematic review	20
Intravitreal MPTP drives retinal ganglion cell loss with oral nicotinamide treatment providing robust neuroprotection	20
Mitochondrial DNA mutations in Medulloblastoma	20
Real-world experience with circulating tumor DNA in cerebrospinal fluid from patients with central nervous system tumors	20
Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease	20
Coping with brain amyloid: genetic heterogeneity and cognitive resilience to Alzheimer’s pathophysiology	19
Early onset senescence and cognitive impairment in a murine model of repeated mTBI	19
Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain	19
Clinicopathological and molecular characterization of a case classified by DNA‑methylation profiling as “CNS embryonal tumor with BRD4–LEUTX fusion”	19
Tau seed amplification assay reveals relationship between seeding and pathological forms of tau in Alzheimer’s disease brain	19
Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease	19
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer’s-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia	19
Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau	19
Retina-to-brain spreading of α-synuclein after intravitreal injection of preformed fibrils	19
The locus coeruleus input to the rostral ventromedial medulla mediates stress-induced colorectal visceral pain	19
Correction to: Integrated genomic analysis reveals actionable targets in pediatric spinal cord low-grade gliomas	18
Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking	18
Personalising glioblastoma medicine: explant organoid applications, challenges and future perspectives	18
Nuclear face of Tau: an inside player in neurodegeneration	18
The role of plasminogen activator inhibitor-2 in pneumococcal meningitis	18
X-linked SBMA model mice display relevant non-neurological phenotypes and their expression of mutant androgen receptor protein in motor neurons is not required for neuromuscular disease	18
Correction: Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer’s disease	18
Correction to: Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease	18
Correction: Host genetics and gut microbiota influence lipid metabolism and inflammation: potential implications for ALS pathophysiology in SOD1G93A mice	18
Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy	18
Quantitative multiplex immunohistochemistry with colorimetric staining (QUIVER) may still benefit from MILAN	18
Disseminated diffuse midline gliomas, H3K27-altered mimicking diffuse leptomeningeal glioneuronal tumors: a diagnostical challenge!	18
Tissue-specific and repeat length-dependent somatic instability of the X-linked dystonia parkinsonism-associated CCCTCT repeat	18
Mical modulates Tau toxicity via cysteine oxidation in vivo	18
Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer’s disease	18
Plasma proteome profiling identifies changes associated to AD but not to FTD	18
AQP4 labels a subpopulation of white matter-dependent glial radial cells affected by pediatric hydrocephalus, and its expression increased in glial microvesicles released to the cerebrospinal fluid in	17
VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology	17
Sex-specific DNA methylation differences in Alzheimer’s disease pathology	17
Spontaneous intracerebral haemorrhage associated with early-onset cerebral amyloid angiopathy and Alzheimer’s disease neuropathological changes five decades after cadaveric dura mater graft	17
Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice	17
Urinary D-asparagine level is decreased by the presence of glioblastoma	17
Amygdala granular fuzzy astrocytes are independently associated with both LATE neuropathologic change and argyrophilic grains: a study of Japanese series with a low to moderate Braak stage	17
Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease	17
A neuropathologic feature of brain aging: multi-lumen vascular profiles	16
Correction: Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicen	16
Loss of glucocorticoid receptor phosphorylation contributes to cognitive and neurocentric damages of the amyloid-β pathway	16
Molecular and clinicopathologic characteristics of CNS embryonal tumors with BRD4::LEUTX fusion	16
Acute axon damage and demyelination are mitigated by 4-aminopyridine (4-AP) therapy after experimental traumatic brain injury	16
Droplet digital PCR-based analyses for robust, rapid, and sensitive molecular diagnostics of gliomas	16
A microdeletion event at 19q13.43 in IDH-mutant astrocytomas is strongly correlated with MYC overexpression	16
Macular structural integrity estimates are associated with Parkinson’s disease genetic risk	16
The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects	16
Loss of presenilin function enhances tau phosphorylation and aggregation in mice	16

Autophagy is affected in patients with hypokalemic periodic paralysis: an involvement in vacuolar myopathy?	16
Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsic	16
Increase in wasteosomes (corpora amylacea) in frontotemporal lobar degeneration with specific detection of tau, TDP-43 and FUS pathology	16
DNA methylation alterations across time and space in paediatric brain tumours	15
Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion	15
Human adipose tissue-derived stem cell extracellular vesicles attenuate ocular hypertension-induced retinal ganglion cell damage by inhibiting microglia- TLR4/MAPK/NF-κB proinflammatory cascade signal	15
Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment	15
Ballooned neurons in semi-recent severe traumatic brain injury	15
Unraveling axonal mechanisms of traumatic brain injury	15
Molecular reclassification reveals low prevalence of germline predisposition in children with ependymoma	15
Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice	15
A sellar presentation of a WNT-activated embryonal tumor: further evidence of an ectopic medulloblastoma	15
ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics	15
COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI)	15
Sporadic Creutzfeldt-Jakob disease VM1: phenotypic and molecular characterization of a novel subtype of human prion disease	15
Spinocerebellar ataxia type 17-digenic TBP/STUB1 disease: neuropathologic features of an autopsied patient	15
Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD	15
Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer’s disease and experimental chronic cerebral hypoperfusion	15
Clinical and molecular characteristics and long-term outcomes of pediatric intracranial meningiomas: a comprehensive analysis from a single neurosurgical center	14
Boosting neuregulin 1 type-III expression hastens SMA motor axon maturation	14
Differential vulnerability of the dentate gyrus to tauopathies in dementias	14
Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicenter retrospe	14
High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy	14
Early alterations of neurovascular unit in the retina in mouse models of tauopathy	14
Correction: Clinical implications of DNA methylation-based integrated classification of histologically defined grade 2 meningiomas	14
Dynamic profiling of medulloblastoma surfaceome	14
Cerebellar granule neurons induce Cyclin D1 before the onset of motor symptoms in Huntington’s disease mice	14
Mild traumatic brain injury induces microvascular injury and accelerates Alzheimer-like pathogenesis in mice	14
NF2 and ZFTA evaluation in the diagnostic algorithm of pediatric posterior fossa ependymoma with H3K27ME3 retained expression	14
Longitudinal DNA methylation analysis of adult-type IDH-mutant gliomas	14
Correction to: Higher angiotensin‑converting enzyme 2 (ACE2) levels in the brain of individuals with Alzheimer’s disease	14
The specific DNA methylation landscape in focal cortical dysplasia ILAE type 3D	14
White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognition	13
Torpor induces reversible tau hyperphosphorylation and accumulation in mice expressing human tau	13
Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load	13
Pure argyrophilic grain disease revisited: independent effects on limbic, neocortical, and striato-pallido-nigral degeneration and the development of dementia in a series with a low to moderate Braak	13
BCOR::CREBBP fusion in malignant neuroepithelial tumor of CNS expands the spectrum of methylation class CNS tumor with BCOR/BCOR(L1)-fusion	13
Temporal patterns of microglial activation in white matter following experimental mild traumatic brain injury: a systematic literature review	13
Perspective of mesenchymal transformation in glioblastoma	13
Distribution of Lewy-related pathology in the brain, spinal cord, and periphery: the population-based Vantaa 85 + study	13
EMP3 sustains oncogenic EGFR/CDK2 signaling by restricting receptor degradation in glioblastoma	13
Evidence of cerebellar TDP-43 loss of function in FTLD-TDP	13
Effects of local reduction of endogenous α-synuclein using antisense oligonucleotides on the fibril-induced propagation of pathology through the neural network in wild-type mice	13
RBM5-AS1 promotes radioresistance in medulloblastoma through stabilization of SIRT6 protein	13
Wolfram syndrome 1b mutation suppresses Mauthner-cell axon regeneration via ER stress signal pathway	13
Traumatic brain injury induces TDP-43 mislocalization and neurodegenerative effects in tissue distal to the primary injury site in a non-transgenic mouse	13
DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome—including in elderly patients	13
Therapeutic potential of targeting Nrf2 by panobinostat in pituitary neuroendocrine tumors	13
Reduced T-cell densities in cranial nerves of patients who died with SARS-CoV-2 infection	13
Interface astrogliosis in contact sport head impacts and military blast exposure	13