eLife

Article	Citations
Correction: Highly contiguous assemblies of 101 drosophilid genomes	711
Whole genomes from the extinct Xerces Blue butterfly can help identify declining insect species	429
Multi-tiered actions of Legionella effectors to modulate host Rab10 dynamics	331
Molecular and mechanical signatures contributing to mouse epidermal differentiation and barrier formation	326
Apoptotic signaling clears engineered Salmonella in an organ-specific manner	298
Wiring up for controlled flight	283
Deciding when to move	261
Shining a light on hematopoietic stem cells	247
Imaging of brain electric field networks with spatially resolved EEG	246
Caspases promote cell proliferation after necrosis	216
Outgrowing self-denial	202
Correction: Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci	181
Allosteric regulation of kinase activity in living cells	172
Shared functional organization between pulvinar-cortical and cortico-cortical connectivity and its structural and molecular imaging correlates	165
osl-dynamics, a toolbox for modeling fast dynamic brain activity	160
Septins function in exocytosis via physical interactions with the exocyst complex in fission yeast cytokinesis	157
Evolution of hind limb morphology of Titanosauriformes (Dinosauria, Sauropoda) analyzed via 3D geometric morphometrics reveals wide-gauge posture as an exaptation for gigantism	156
scRNA+TCR-seq reveals the proportion and characteristics of dual TCR Treg cells in mouse lymphoid and non-lymphoid tissues	151
Single-cell profiling reveals the intratumor heterogeneity and immunosuppressive microenvironment in cervical adenocarcinoma	145
Comprehensive mutagenesis maps the effect of all single-codon mutations in the AAV2 rep gene on AAV production	145
Space as a scaffold for rotational generalisation of abstract concepts	144
Companion cells with high florigen production express other small proteins and reveal a nitrogen-sensitive FT repressor	143
Correction: Drp1 is required for AgRP neuronal activity and feeding	140
DeePosit, an AI-based tool for detecting mouse urine and fecal depositions from thermal video clips of behavioral experiments	138
SARS-CoV-2 NSP13 interacts with TEAD to suppress Hippo-YAP signaling	138

Correction: Distinct neurexin-cerebellin complexes control AMPA- and NMDA-receptor responses in a circuit-dependent manner	133
Conduction pathway for potassium through the Escherichia coli pump KdpFABC	132
Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function	131
Courtship behaviour reveals temporal regularity is a critical social cue in mouse communication	131
Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration	128
Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances	128
Rapid and inducible mislocalization of endogenous TDP43 in a novel human model of amyotrophic lateral sclerosis	128
Resting natural killer cells promote the progress of colon cancer liver metastasis by elevating tumor-derived stem cell factor	127
CTFFIND5 provides improved insight into quality, tilt, and thickness of TEM samples	127
Differential functions of the dorsal and intermediate regions of the hippocampus for optimal goal-directed navigation in VR space	126
EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis	118
Cingulate cortex shapes early postnatal development of social vocalizations	117
Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis	117
Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration	111
Using adopted individuals to partition indirect maternal genetic effects into prenatal and postnatal effects on offspring phenotypes	110
Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme	110
Robust T cell activation requires an eIF3-driven burst in T cell receptor translation	109
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes	106
Measurements and simulations of microtubule growth imply strong longitudinal interactions and reveal a role for GDP on the elongating end	106
ZAF, the first open source fully automated feeder for aquatic facilities	106
Impact of a human gut microbe on Vibrio cholerae host colonization through biofilm enhancement	106
A neural progenitor mitotic wave is required for asynchronous axon outgrowth and morphology	105
Decoding the activated stem cell phenotype of the neonatally maturing pituitary	103
Airway basal cells show regionally distinct potential to undergo metaplastic differentiation	102
T cells discriminate between groups C1 and C2 HLA-C	102
Spatial transcriptomics reveals metabolic changes underly age-dependent declines in digit regeneration	99
Mg2+-dependent conformational equilibria in CorA and an integrated view on transport regulation	98
High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy	98
Recombinant single-cycle influenza virus with exchangeable pseudotypes allows repeated immunization to augment anti-tumour immunity with immune checkpoint inhibitors	97
COVID-19 cluster size and transmission rates in schools from crowdsourced case reports	96
Interplay between external inputs and recurrent dynamics during movement preparation and execution in a network model of motor cortex	96
State-dependent representations of mixtures by the olfactory bulb	94
Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist-mediated activation mechanism	93
Sex differences and sex bias in human circadian and sleep physiology research	93
NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis	93
Katanin, kinesin-13, and ataxin-2 inhibit premature interaction between maternal and paternal genomes in C. elegans zygotes	92
Reversal of the adipostat control of torpor during migration in hummingbirds	92
Altered visual cortex excitatory/inhibitory ratio following transient congenital visual deprivation in humans	92
Nutritional state-dependent modulation of insulin-producing cells in Drosophila	91
A new potential strategy for cutaneous squamous cell carcinoma treatment by generating serum-based antibodies from tumor-exposed mice	91
Muscarinic receptors mediate motivation via preparatory neural activity in humans	91
Astrocytes mediate two forms of spike timing-dependent depression at entorhinal cortex-hippocampal synapses	90
Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia	90
The phytoplasma SAP54 effector acts as a molecular matchmaker for leafhopper vectors by targeting plant MADS-box factor SVP	90
NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in solitary fibrous tumors	88
DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids	87
Impact of maximal overexpression of a non-toxic protein on yeast cell physiology	87
Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms	85
Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier	84
Differential regulation of the proteome and phosphoproteome along the dorso-ventral axis of the early Drosophila embryo	84

Multisensory integration enhances audiovisual responses in the Mauthner cell	84
Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA-assisted uptake and ribosomal protein RplL sensitivity	83
Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis	82
A direct neural signature of serial dependence in working memory	82
AARS2 ameliorates myocardial ischemia via fine-tuning PKM2-mediated metabolism	81
Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape	81
How honey bees make fast and accurate decisions	80
Relating pathogenic loss-of-function mutations in humans to their evolutionary fitness costs	80
High-resolution imaging of the osteogenic and angiogenic interface at the site of murine cranial bone defect repair via multiphoton microscopy	79
High-grade serous ovarian carcinoma organoids as models of chromosomal instability	78
Evolution of an extreme hemoglobin phenotype contributed to the sub-Arctic specialization of extinct Steller’s sea cows	78
Mechanism of substrate binding and transport in BASS transporters	77
Ligand bias underlies differential signaling of multiple FGFs via FGFR1	77
Somatic mutation rates scale with time not growth rate in long-lived tropical trees	77
PIMT is a novel and potent suppressor of endothelial activation	77
BATF relieves hepatic steatosis by inhibiting PD1 and promoting energy metabolism	77
An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor	76
Goal-directed vocal planning in a songbird	76
Interrogating basal ganglia circuit function in people with Parkinson’s disease and dystonia	76
Asymmetric distribution of color-opponent response types across mouse visual cortex supports superior color vision in the sky	76
The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation	75
Direct observation of the neural computations underlying a single decision	75
Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism	75
Mouthparts of the bumblebee (Bombus terrestris) exhibit poor acuity for the detection of pesticides in nectar	74
Genetic and karyotype divergence between parents affect clonality and sterility in hybrids	74
Spatial transformation of multi-omics data unlocks novel insights into cancer biology	74
De novo identification of universal cell mechanics gene signatures	74
An emerging view of neural geometry in motor cortex supports high-performance decoding	74
Self-formation of concentric zones of telencephalic and ocular tissues and directional retinal ganglion cell axons	73
Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis	73
Genetic screen identified PRMT5 as a neuroprotection target against cerebral ischemia	73
Antipsychotic drugs selectively decorrelate long-range interactions in deep cortical layers	72
A reductionist paradigm for high-throughput behavioural fingerprinting in Drosophila melanogaster	72
Are single-peaked tuning curves tuned for speed rather than accuracy?	72
Linking genotypic and phenotypic changes in the E. coli long-term evolution experiment using metabolomics	72
Amelioration of non-alcoholic fatty liver disease by targeting adhesion G protein-coupled receptor F1 (Adgrf1)	71
Dynamics of co-substrate pools can constrain and regulate metabolic fluxes	71
Germinal center B cells that acquire nuclear proteins are specifically suppressed by follicular regulatory T cells	71
Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide in the mouse gut depends on the resident microbiota	70
Integrating analog and digital modes of gene expression at Arabidopsis FLC	70
Recalibrating vision-for-action requires years after sight restoration from congenital cataracts	70
Insight into the evolutionary assemblage of cranial kinesis from a Cretaceous bird	70
Sensory input-dependent gain modulation of the optokinetic nystagmus by mid-infrared stimulation in pigeons	70
A connectomics-based taxonomy of mammals	70
Nucleotide-level linkage of transcriptional elongation and polyadenylation	69
Functional and structural segregation of overlapping helices in HIV-1	69
Peroxiredoxin 5 regulates osteogenic differentiation through interaction with hnRNPK during bone regeneration	69
A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma	69
Nonlinear transient amplification in recurrent neural networks with short-term plasticity	69
Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford progeria syndrome	69
V-ATPase V0a1 promotes Weibel–Palade body biogenesis through the regulation of membrane fission	69
A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes	69
The ER tether VAPA is required for proper cell motility and anchors ER-PM contact sites to focal adhesions	68
Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration	68
Using light and X-ray scattering to untangle complex neuronal orientations and validate diffusion MRI	68
Intrinsic excitability mechanisms of neuronal ensemble formation	67
Intracranial human recordings reveal association between neural activity and perceived intensity for the pain of others in the insula	67
A meta-analysis of the association between male dimorphism and fitness outcomes in humans	67
Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from people with cystic fibrosis	67
Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma	66
The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial	66
Cell crowding activates pro-invasive mechanotransduction pathway in high-grade DCIS via TRPV4 inhibition and cell volume reduction	66
A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective, and anti-inflammatory properties following sta	66
Altered thymic niche synergistically drives the massive proliferation of malignant thymocytes	66
Functional gradients in the human lateral prefrontal cortex revealed by a comprehensive coordinate-based meta-analysis	66
Cortico-striatal action control inherent of opponent cognitive-motivational styles	66
TRPV4 activation by TGFβ2 enhances cellular contractility and drives ocular hypertension	65
Separable dorsal raphe dopamine projections mimic the facets of a loneliness-like state	65
Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability	65
Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens	65
Chronic stress impairs autoinhibition in neurons of the locus coeruleus to increase asparagine endopeptidase activity	65
The influence of temporal context on vision over multiple time scales	64
Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria	64
Cryo-EM structures of a pentameric ligand-gated ion channel in liposomes	64
Multi-dimensional social relationships shape social attention in monkeys	64
Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma	64
Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA	63
Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single-cell RNA sequencing	63
Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum	63
β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury	63

Antagonist actions of CMK-1/CaMKI and TAX-6/calcineurin along the C. elegans thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuli	63
An annotated introductory reading list for neurodiversity	63
Hierarchical encoding of natural sound mixtures in ferret auditory cortex	63
Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation	63
ACVR2A facilitates trophoblast cell invasion through TCF7/c-JUN pathway in pre-eclampsia progression	63
Single-cell transcriptomes of zebrafish germline reveal progenitor types and feminization by Foxl2l	63
The non-muscle actinopathy-associated mutation E334Q in cytoskeletal γ-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins	62
Sexual failure decreases sweet taste perception in male Drosophila via dopaminergic signaling	62
Iridescent structural coloration in a crested Cretaceous enantiornithine bird from the Jehol Biota	62
Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process	62
A causal role of the NMDA receptor in recurrent processing during perceptual integration	62
MCPH1 inhibits Condensin II during interphase by regulating its SMC2-Kleisin interface	62
Functionally important residues from graph analysis of coevolved dynamic couplings	62
Preclinical systematic review of CCR5 antagonists as cerebroprotective and stroke recovery enhancing agents	62
Analysis of long and short enhancers in melanoma cell states	61
Patterns of interdivision time correlations reveal hidden cell cycle factors	61
Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors	61
Neural excursions from manifold structure explain patterns of learning during human sensorimotor adaptation	61
Cellular and molecular dynamics in the lungs of neonatal and juvenile mice in response to E. coli	61
Cortical adaptation to sound reverberation	61
Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity	61
Caveolae and Bin1 form ring-shaped platforms for T-tubule initiation	60
Targeting the fatty acid binding proteins disrupts multiple myeloma cell cycle progression and MYC signaling	60
circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA	60
Mutant SF3B1 promotes malignancy in PDAC	60
The proteolysis of ZP proteins is essential to control cell membrane structure and integrity of developing tracheal tubes in Drosophila	60
Phylodynamics of SARS-CoV-2 in France, Europe, and the world in 2020	60
Guanidine production by plant homoarginine-6-hydroxylases	60
PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification	59
SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells	59
A ‘double-edged’ role for type-5 metabotropic glutamate receptors in pain disclosed by light-sensitive drugs	59
Biocalcification in porcelaneous foraminifera	59
Predicting individual traits from models of brain dynamics accurately and reliably using the Fisher kernel	58
Alternative splicing across the tree of life	58
Macro-scale patterns in functional connectivity associated with ongoing thought patterns and dispositional traits	58
Language experience shapes predictive coding of rhythmic sound sequences	58
G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs	58
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4	58
Pigmentation level of human iPSC-derived RPE does not indicate a specific gene expression profile	58
Early steps of protein disaggregation by Hsp70 chaperone and class B J-domain proteins are shaped by Hsp110	58
Human induced pluripotent stem cell-derived cardiomyocytes to study inflammation-induced aberrant calcium transient	57
Serial attentional resource allocation during parallel feature value tracking	57
Emergence of ion-channel-mediated electrical oscillations in Escherichia coli biofilms	57
The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion	57
Antigenic strain diversity predicts different biogeographic patterns of maintenance and decline of antimalarial drug resistance	57
Evolutionary rate covariation is a reliable predictor of co-functional interactions but not necessarily physical interactions	57
Netrin signaling mediates survival of dormant epithelial ovarian cancer cells	57
The substrate-binding domains of the osmoregulatory ABC importer OpuA transiently interact	57
Movies reveal the fine-grained organization of infant visual cortex	57
Reliable protein–protein docking with AlphaFold, Rosetta, and replica exchange	57
Hammerhead-type FXR agonists induce an enhancer RNA Fincor that ameliorates nonalcoholic steatohepatitis in mice	57
The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition	57
RAG1 and RAG2 non-core regions are implicated in leukemogenesis and off-target V(D)J recombination in BCR-ABL1-driven B-cell lineage lymphoblastic leukemia	57
Genetic and dietary modulators of the inflammatory response in the gastrointestinal tract of the BXD mouse genetic reference population	56
Combining mutation and recombination statistics to infer clonal families in antibody repertoires	56
Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response	56
Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis	56
Evidence accumulation, not ‘self-control’, explains dorsolateral prefrontal activation during normative choice	56
Lipid hydroperoxides promote sarcopenia through carbonyl stress	56
Computational modeling of threat learning reveals links with anxiety and neuroanatomy in humans	56
Long COVID in cancer patients: preponderance of symptoms in majority of patients over long time period	56
Best practices to promote rigor and reproducibility in the era of sex-inclusive research	56
Ketamine induces multiple individually distinct whole-brain functional connectivity signatures	56
Brain areas for reversible symbolic reference, a potential singularity of the human brain	56
Intestinal GCN2 controls Drosophila systemic growth in response to Lactiplantibacillus plantarum symbiotic cues encoded by r/tRNA operons	56
SAFB regulates hippocampal stem cell fate by targeting Drosha to destabilize Nfib mRNA	56
Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC)	56
Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9	55
Conditional and unconditional components of aversively motivated freezing, flight and darting in mice	55
Add mass spectrometry to the pandemic toolbox	55
Horizontally transferred cell-free chromatin particles function as autonomous ‘satellite genomes’ and vehicles for transposable elements within host cells	55
Functional visualization of NK cell-mediated killing of metastatic single tumor cells	55
Dynamic analysis of circulating tumor DNA to predict the prognosis and monitor the treatment response of patients with metastatic triple-negative breast cancer: A prospective study	55
Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16	55
Pervasive translation in Mycobacterium tuberculosis	55
Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium	55
Synergistic phase separation of two pathways promotes integrin clustering and nascent adhesion formation	55
A computationally informed comparison between the strategies of rodents and humans in visual object recognition	55
Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation	54
An optogenetic cell therapy to restore control of target muscles in an aggressive mouse model of amyotrophic lateral sclerosis	54
Medial anterior prefrontal cortex stimulation downregulates implicit reactions to threats and prevents the return of fear	54
Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses	54
Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster	54
Nonlinear feedback modulation contributes to the optimization of flexible decision-making	54
An antagonism between Spinophilin and Syd-1 operates upstream of memory-promoting presynaptic long-term plasticity	54
A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx	54
Position representations of moving objects align with real-time position in the early visual response	54
S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress	54
Neural geometry from mixed sensorimotor selectivity for predictive sensorimotor control	54
Galvanic current activates the NLRP3 inflammasome to promote Type I collagen production in tendon	53
The deep-rooted origin of disulfide-rich spider venom toxins	53
Structural mechanism of strand exchange by the RAD51 filament	53
GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia	53
Brain and molecular mechanisms underlying the nonlinear association between close friendships, mental health, and cognition in children	53
AARS2 ameliorates myocardial ischemia via fine-tuning PKM2-mediated metabolism	53