(The H4-Index of eLife is 101. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-11-01 to 2023-11-01.)
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants1083
The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications1036
SARS-CoV-2 (COVID-19) by the numbers713
Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3601
A connectome and analysis of the adult Drosophila central brain490
Atomic structures of respiratory complex III2, complex IV, and supercomplex III2-IV from vascular plants482
Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission366
Common activation mechanism of class A GPCRs281
Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification272
Ten simple rules for the computational modeling of behavioral data272
A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm272
COVID-19 medical papers have fewer women first authors than expected265
Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19261
Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset255
Evidence for transmission of COVID-19 prior to symptom onset229
Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm229
Variable prediction accuracy of polygenic scores within an ancestry group228
Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics226
ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities225
N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2222
A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice219
How to measure and evaluate binding affinities206
Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome201
Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?196
The connectome of the adult Drosophila mushroom body provides insights into function196
Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy192
Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation189
Antigen presentation and tumor immunogenicity in cancer immunotherapy response prediction183
Derivation of trophoblast stem cells from naïve human pluripotent stem cells177
Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment168
Single cell transcriptional signatures of the human placenta in term and preterm parturition166
Antimicrobial resistance and COVID-19: Intersections and implications164
An electrophysiological marker of arousal level in humans161
A 10-year follow-up study of sex inclusion in the biological sciences157
SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway155
Tight nuclear tethering of cGAS is essential for preventing autoreactivity154
Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study153
Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up150
DunedinPACE, a DNA methylation biomarker of the pace of aging149
Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration149
Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner149
DNA damage—how and why we age?148
The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy146
Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane146
An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species143
Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies141
Cancer-associated fibroblasts and their influence on tumor immunity and immunotherapy140
FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices138
A genetic, genomic, and computational resource for exploring neural circuit function137
Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls135
Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart134
Lytic transglycosylases mitigate periplasmic crowding by degrading soluble cell wall turnover products133
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types132
A whole-brain connectivity map of mouse insular cortex132
Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study131
Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin130
Modular output circuits of the fastigial nucleus for diverse motor and nonmotor functions of the cerebellar vermis130
Spatiotemporal constraints on optogenetic inactivation in cortical circuits130
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation129
Structure of the bacterial ribosome at 2 Å resolution129
Sampling alternative conformational states of transporters and receptors with AlphaFold2128
Defining the role of pulmonary endothelial cell heterogeneity in the response to acute lung injury127
Accurate and versatile 3D segmentation of plant tissues at cellular resolution126
A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection125
The natverse, a versatile toolbox for combining and analysing neuroanatomical data124
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model124
The single-cell eQTLGen consortium123
A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress121
Neuronal timescales are functionally dynamic and shaped by cortical microarchitecture121
Discovery of several thousand highly diverse circular DNA viruses121
Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation120
Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo120
Viral load and contact heterogeneity predict SARS-CoV-2 transmission and super-spreading events119
Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition119
Noninvasive quantification of axon radii using diffusion MRI116
Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq116
Mechanistic theory predicts the effects of temperature and humidity on inactivation of SARS-CoV-2 and other enveloped viruses114
Trends in snakebite deaths in India from 2000 to 2019 in a nationally representative mortality study114
Development of a confinable gene drive system in the human disease vector Aedes aegypti112
Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis112
Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes112
Beyond the RNA-dependent function of LncRNA genes111
An open label trial of anakinra to prevent respiratory failure in COVID-19110
A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes109
TRex, a fast multi-animal tracking system with markerless identification, and 2D estimation of posture and visual fields109
Sex differences in biological aging with a focus on human studies108
A single-cell survey of Drosophila blood108
The OpenNeuro resource for sharing of neuroscience data106
Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell106
Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block106
Brain aging comprises many modes of structural and functional change with distinct genetic and biophysical associations103
Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides103
Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment103
SARS-CoV-2 strategically mimics proteolytic activation of human ENaC102
Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function102
SpikeInterface, a unified framework for spike sorting102
A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila101
Adjusting for age improves identification of gut microbiome alterations in multiple diseases101
A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids101
ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL101
Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens101