OOIR: Observatory of International Research

Papers

(The H4-Index of eLife is 83. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability	591
Cryo-EM structures of a pentameric ligand-gated ion channel in liposomes	387
Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single-cell RNA sequencing	321
New insights into anatomical connectivity along the anterior–posterior axis of the human hippocampus using in vivo quantitative fibre tracking	312
Airway basal cells show regionally distinct potential to undergo metaplastic differentiation	311
Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation	301
Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity	289
Patterns of interdivision time correlations reveal hidden cell cycle factors	286
Intracranial human recordings reveal association between neural activity and perceived intensity for the pain of others in the insula	259
Intrinsic excitability mechanisms of neuronal ensemble formation	244
Separable dorsal raphe dopamine projections mimic the facets of a loneliness-like state	243
A meta-analysis of the association between male dimorphism and fitness outcomes in humans	242
SAFB regulates hippocampal stem cell fate by targeting Drosha to destabilize Nfib mRNA	222
A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma	219
Whole genomes from the extinct Xerces Blue butterfly can help identify declining insect species	215
Germinal center B cells that acquire nuclear proteins are specifically suppressed by follicular regulatory T cells	212
Serial attentional resource allocation during parallel feature value tracking	192
Caveolae and Bin1 form ring-shaped platforms for T-tubule initiation	184
High-grade serous ovarian carcinoma organoids as models of chromosomal instability	175
The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation	173
Brain and molecular mechanisms underlying the nonlinear association between close friendships, mental health, and cognition in children	167
Pigmentation level of human iPSC-derived RPE does not indicate a specific gene expression profile	163
Emergence of ion-channel-mediated electrical oscillations in Escherichia coli biofilms	161
An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor	158
Multi-tiered actions of Legionella effectors to modulate host Rab10 dynamics	155

Cingulate cortex shapes early postnatal development of social vocalizations	146
Enhancing bone regeneration and osseointegration using rhPTH(1-34) and dimeric R25CPTH(1-34) in an osteoporotic beagle model	142
Differential functions of the dorsal and intermediate regions of the hippocampus for optimal goal-directed navigation in VR space	141
Asymmetric distribution of color-opponent response types across mouse visual cortex supports superior color vision in the sky	141
Antipsychotic drugs selectively decorrelate long-range interactions in deep cortical layers	138
Ligand bias underlies differential signaling of multiple FGFs via FGFR1	135
CTFFIND5 provides improved insight into quality, tilt, and thickness of TEM samples	134
Resting natural killer cells promote the progress of colon cancer liver metastasis by elevating tumor-derived stem cell factor	134
Variation in the basal immune state and implications for disease	132
A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes	128
A new potential strategy for cutaneous squamous cell carcinoma treatment by generating serum-based antibodies from tumor-exposed mice	127
Reliable protein–protein docking with AlphaFold, Rosetta, and replica exchange	125
Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration	123
An optogenetic cell therapy to restore control of target muscles in an aggressive mouse model of amyotrophic lateral sclerosis	122
Dynamic analysis of circulating tumor DNA to predict the prognosis and monitor the treatment response of patients with metastatic triple-negative breast cancer: A prospective study	122
Mouthparts of the bumblebee (Bombus terrestris) exhibit poor acuity for the detection of pesticides in nectar	122
Hammerhead-type FXR agonists induce an enhancer RNA Fincor that ameliorates nonalcoholic steatohepatitis in mice	121
Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis	120
Single-cell profiling reveals the intratumor heterogeneity and immunosuppressive microenvironment in cervical adenocarcinoma	120
Mechanism of substrate binding and transport in BASS transporters	119
Linking genotypic and phenotypic changes in the E. coli long-term evolution experiment using metabolomics	116
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4	116
Guanidine production by plant homoarginine-6-hydroxylases	115
Human induced pluripotent stem cell-derived cardiomyocytes to study inflammation-induced aberrant calcium transient	115
Correction: Distinct neurexin-cerebellin complexes control AMPA- and NMDA-receptor responses in a circuit-dependent manner	114
Apoptotic signaling clears engineered Salmonella in an organ-specific manner	114
Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape	109
Muscarinic receptors mediate motivation via preparatory neural activity in humans	107
ACVR2A facilitates trophoblast cell invasion through TCF7/c-JUN pathway in pre-eclampsia progression	106
Preclinical systematic review of CCR5 antagonists as cerebroprotective and stroke recovery enhancing agents	106
Antagonist actions of CMK-1/CaMKI and TAX-6/calcineurin along the C. elegans thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuli	105
Neural geometry from mixed sensorimotor selectivity for predictive sensorimotor control	104
The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial	103
Single-cell transcriptomes of zebrafish germline reveal progenitor types and feminization by Foxl2l	101
Imaging of brain electric field networks with spatially resolved EEG	101
Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis	100
Reversal of the adipostat control of torpor during migration in hummingbirds	99
Amelioration of non-alcoholic fatty liver disease by targeting adhesion G protein-coupled receptor F1 (Adgrf1)	99
A quadratic model captures the human V1 response to variations in chromatic direction and contrast	99
Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria	97
Multi-dimensional social relationships shape social attention in monkeys	94
Cortical adaptation to sound reverberation	94
Computational modeling of threat learning reveals links with anxiety and neuroanatomy in humans	93
A new early branching armored dinosaur from the Lower Jurassic of southwestern China	92
Conditional and unconditional components of aversively motivated freezing, flight and darting in mice	92
Evidence accumulation, not ‘self-control’, explains dorsolateral prefrontal activation during normative choice	91
GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia	89
STING mediates immune responses in the closest living relatives of animals	89
T cells discriminate between groups C1 and C2 HLA-C	88
Add mass spectrometry to the pandemic toolbox	88

Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration	87
Peroxiredoxin 5 regulates osteogenic differentiation through interaction with hnRNPK during bone regeneration	87
A neural progenitor mitotic wave is required for asynchronous axon outgrowth and morphology	87
Decoding the activated stem cell phenotype of the neonatally maturing pituitary	86
Measurements and simulations of microtubule growth imply strong longitudinal interactions and reveal a role for GDP on the elongating end	86
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes	84
Spatial transformation of multi-omics data unlocks novel insights into cancer biology	83
Spatial transcriptomics reveals metabolic changes underly age-dependent declines in digit regeneration	83
Analysis of meiosis in Pristionchus pacificus reveals plasticity in homolog pairing and synapsis in the nematode lineage	83
TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase	83