OOIR: Observatory of International Research

Papers

(The H4-Index of eLife is 86. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Comprehensive mutagenesis maps the effect of all single-codon mutations in the AAV2 rep gene on AAV production	1137
The importance of individual beliefs in assessing treatment efficacy	407
Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model	338
The layered costs and benefits of translational redundancy	288
Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia	288
Targeted multi-omic analysis of human skin tissue identifies alterations of conventional and unconventional T cells associated with burn injury	266
Heparan sulfate-dependent RAGE oligomerization is indispensable for pathophysiological functions of RAGE	260
Auditory mismatch responses are differentially sensitive to changes in muscarinic acetylcholine versus dopamine receptor function	234
Controlling periodic long-range signalling to drive a morphogenetic transition	225
ZAF, the first open source fully automated feeder for aquatic facilities	223
The extraordinary metabolism of vitamin D	219
Mouse gingival single-cell transcriptomic atlas identified a novel fibroblast subpopulation activated to guide oral barrier immunity in periodontitis	215
Cellular assays identify barriers impeding iron-sulfur enzyme activity in a non-native prokaryotic host	215
The unmitigated profile of COVID-19 infectiousness	197
Phasic oxygen dynamics confounds fast choline-sensitive biosensor signals in the brain of behaving rodents	194
GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway	192
Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation	174
Wiring up for controlled flight	171
Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition	169
Neural attentional filters and behavioural outcome follow independent individual trajectories over the adult lifespan	169
A double dissociation between semantic and spatial cognition in visual to default network pathways	166
Correction: Gene regulatory patterning codes in early cell fate specification of the C. elegans embryo	162
Retraction: Proteasome storage granules protect proteasomes from autophagic degradation upon carbon starvation	160
Persistent cross-species transmission systems dominate Shiga toxin-producing Escherichia coli O157:H7 epidemiology in a high incidence region: A genomic epidemiology study	158
Post-retrieval noradrenergic activation impairs subsequent memory depending on cortico-hippocampal reactivation	154

Reprogramming of cardiac phosphoproteome, proteome, and transcriptome confers resilience to chronic adenylyl cyclase-driven stress	153
Risk-sensitive learning is a winning strategy for leading an urban invasion	153
Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system	147
A binding site for phosphoinositides described by multiscale simulations explains their modulation of voltage-gated sodium channels	145
Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism	144
DNA passes through cohesin’s hinge as well as its Smc3–kleisin interface	143
Modulation of pulsatile GnRH dynamics across the ovarian cycle via changes in the network excitability and basal activity of the arcuate kisspeptin network	143
Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide in the mouse gut depends on the resident microbiota	142
The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus	141
Colicin E1 opens its hinge to plug TolC	138
Asymmetric distribution of color-opponent response types across mouse visual cortex supports superior color vision in the sky	136
Surveying the experience of postdocs in the United States before and during the COVID-19 pandemic	134
Identification of drugs associated with reduced severity of COVID-19 – a case-control study in a large population	133
Global organization of neuronal activity only requires unstructured local connectivity	132
Associations of combined phenotypic aging and genetic risk with incident cancer: A prospective cohort study	131
A robust brain network for sustained attention from adolescence to adulthood that predicts later substance use	131
Prediction of diabetic kidney disease risk using machine learning models: A population-based cohort study of Asian adults	130
EEG-fMRI in awake rat and whole-brain simulations show decreased brain responsiveness to sensory stimulations during absence seizures	128
Open science takes on Parkinson’s disease	127
Neuro-evolutionary evidence for a universal fractal primate brain shape	127
Pectin methylesterase activity is required for RALF1 peptide signalling output	118
Combining mutation and recombination statistics to infer clonal families in antibody repertoires	118
Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas	117
Pectin methylesterase activity is required for RALF1 peptide signalling output	117
A unique cell division protein critical for the assembly of the bacterial divisome	116
Differential regulation of the proteome and phosphoproteome along the dorso-ventral axis of the early Drosophila embryo	113
A MSTNDel73C mutation with FGF5 knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasia	111
DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids	110
A MSTNDel73C mutation with FGF5 knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasia	110
Activation of polycystin-1 signaling by binding of stalk-derived peptide agonists	108
Peroxiredoxin 5 regulates osteogenic differentiation through interaction with hnRNPK during bone regeneration	108
An integrative study of five biological clocks in somatic and mental health	107
A novel bioinformatics pipeline for the identification of immune inhibitory receptors as potential therapeutic targets	107
Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity	105
Cholinergic and noradrenergic axonal activity contains a behavioral-state signal that is coordinated across the dorsal cortex	103
Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase	102
Early stage NSCLS patients’ prognostic prediction with multi-information using transformer and graph neural network model	101
Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration	100
Binding to nucleosome poises human SIRT6 for histone H3 deacetylation	99
Targeted anatomical and functional identification of antinociceptive and pronociceptive serotonergic neurons that project to the spinal dorsal horn	99
Cancer genome and tumor microenvironment: Reciprocal crosstalk shapes lung cancer plasticity	98
Nitrogenase resurrection and the evolution of a singular enzymatic mechanism	98
Major genetic discontinuity and novel toxigenic species in Clostridioides difficile taxonomy	95
In vivo fluorescence lifetime imaging of macrophage intracellular metabolism during wound responses in zebrafish	93
Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation	93
Nonlinear transient amplification in recurrent neural networks with short-term plasticity	92
Adverse childhood experiences and resilience among adult women: A population-based study	92
Hydrop enables droplet-based single-cell ATAC-seq and single-cell RNA-seq using dissolvable hydrogel beads	92
CLAMP and Zelda function together to promote Drosophila zygotic genome activation	92
Spatial–temporal order–disorder transition in angiogenic NOTCH signaling controls cell fate specification	91

Postsynaptic burst reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputs	91
Is creatine a CNS neurotransmitter?	91
New insights into anatomical connectivity along the anterior–posterior axis of the human hippocampus using in vivo quantitative fibre tracking	90
Molecular tuning of sea anemone stinging	90
Evolutionary convergence of a neural mechanism in the cavefish lateral line system	89
Pan-cortical 2-photon mesoscopic imaging and neurobehavioral alignment in awake, behaving mice	89
β-cell intrinsic dynamics rather than gap junction structure dictates subpopulations in the islet functional network	88
Quantitative mapping of proteasome interactomes and substrates using ProteasomeID	87
How inhibitory and excitatory inputs gate output of the inferior olive	86
Quantitative mapping of proteasome interactomes and substrates using ProteasomeID	86
Differential dopaminergic modulation of spontaneous cortico–subthalamic activity in Parkinson’s disease	86
Jointly looking to the past and the future in visual working memory	86