OOIR: Observatory of International Research

Papers

(The H4-Index of eLife is 101. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-11-01 to 2023-11-01.)

Article	Citations
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants	1083
The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications	1036
SARS-CoV-2 (COVID-19) by the numbers	713
Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3	601
A connectome and analysis of the adult Drosophila central brain	490
Atomic structures of respiratory complex III2, complex IV, and supercomplex III2-IV from vascular plants	482
Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission	366
Common activation mechanism of class A GPCRs	281
Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification	272
Ten simple rules for the computational modeling of behavioral data	272
A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm	272
COVID-19 medical papers have fewer women first authors than expected	265
Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19	261
Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset	255
Evidence for transmission of COVID-19 prior to symptom onset	229
Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm	229
Variable prediction accuracy of polygenic scores within an ancestry group	228
Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics	226
ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities	225
N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2	222
A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice	219
How to measure and evaluate binding affinities	206
Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome	201
Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?	196
The connectome of the adult Drosophila mushroom body provides insights into function	196

Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy	192
Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation	189
Antigen presentation and tumor immunogenicity in cancer immunotherapy response prediction	183
Derivation of trophoblast stem cells from naïve human pluripotent stem cells	177
Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment	168
Single cell transcriptional signatures of the human placenta in term and preterm parturition	166
Antimicrobial resistance and COVID-19: Intersections and implications	164
An electrophysiological marker of arousal level in humans	161
A 10-year follow-up study of sex inclusion in the biological sciences	157
SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway	155
Tight nuclear tethering of cGAS is essential for preventing autoreactivity	154
Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study	153
Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up	150
DunedinPACE, a DNA methylation biomarker of the pace of aging	149
Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration	149
Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner	149
DNA damage—how and why we age?	148
The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy	146
Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane	146
An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species	143
Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies	141
Cancer-associated fibroblasts and their influence on tumor immunity and immunotherapy	140
FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices	138
A genetic, genomic, and computational resource for exploring neural circuit function	137
Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls	135
Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart	134
Lytic transglycosylases mitigate periplasmic crowding by degrading soluble cell wall turnover products	133
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types	132
A whole-brain connectivity map of mouse insular cortex	132
Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study	131
Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin	130
Modular output circuits of the fastigial nucleus for diverse motor and nonmotor functions of the cerebellar vermis	130
Spatiotemporal constraints on optogenetic inactivation in cortical circuits	130
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation	129
Structure of the bacterial ribosome at 2 Å resolution	129
Sampling alternative conformational states of transporters and receptors with AlphaFold2	128
Defining the role of pulmonary endothelial cell heterogeneity in the response to acute lung injury	127
Accurate and versatile 3D segmentation of plant tissues at cellular resolution	126
A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection	125
The natverse, a versatile toolbox for combining and analysing neuroanatomical data	124
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model	124
The single-cell eQTLGen consortium	123
A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress	121
Neuronal timescales are functionally dynamic and shaped by cortical microarchitecture	121
Discovery of several thousand highly diverse circular DNA viruses	121
Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation	120
Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo	120
Viral load and contact heterogeneity predict SARS-CoV-2 transmission and super-spreading events	119
Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition	119
Noninvasive quantification of axon radii using diffusion MRI	116

Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq	116
Mechanistic theory predicts the effects of temperature and humidity on inactivation of SARS-CoV-2 and other enveloped viruses	114
Trends in snakebite deaths in India from 2000 to 2019 in a nationally representative mortality study	114
Development of a confinable gene drive system in the human disease vector Aedes aegypti	112
Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis	112
Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes	112
Beyond the RNA-dependent function of LncRNA genes	111
An open label trial of anakinra to prevent respiratory failure in COVID-19	110
A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes	109
TRex, a fast multi-animal tracking system with markerless identification, and 2D estimation of posture and visual fields	109
Sex differences in biological aging with a focus on human studies	108
A single-cell survey of Drosophila blood	108
The OpenNeuro resource for sharing of neuroscience data	106
Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell	106
Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block	106
Brain aging comprises many modes of structural and functional change with distinct genetic and biophysical associations	103
Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides	103
Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment	103
SARS-CoV-2 strategically mimics proteolytic activation of human ENaC	102
Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function	102
SpikeInterface, a unified framework for spike sorting	102
A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila	101
Adjusting for age improves identification of gut microbiome alterations in multiple diseases	101
A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids	101
ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL	101
Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens	101