OOIR: Observatory of International Research

Papers

(The median citation count of Clinical & Translational Immunology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
	42
	37
Biomarkers to predict and diagnose pulmonary complications in children post haematopoietic stem cell transplant	28
Circulating cytokine and chemokine patterns associated with cytomegalovirus reactivation after stem cell transplantation	27
SARS‐CoV‐2‐associated T‐cell infiltration in the central nervous system	25
Seropositivity against rubella virus envelope protein 1, but not 2, is associated with an increased risk of multiple sclerosis	22
Spatial omics for profiling the dynamic tumor microenvironment	21
Characteristics of PD‐1⁺CD4⁺ T cells in peripheral blood and synovium of rheumatoid arthritis patients	19
The spectrum of B cells in the pathogenesis, diagnosis and therapeutic applications of immunoglobulin G4‐related disease	19
Polyfunctional T peripheral helper cells are associated with the magnitude and durability of antibody responses after COVID‐19	18
An optimised whole blood interleukin‐2 release assay is more sensitive than interferon‐γ ELIS pot for detecting and quantifying gluten‐specific	16
	14
Targeting BMI‐1 to deplete antibody‐secreting cells in autoimmunity	14
	14
	14
The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation	13
Effects of extremely preterm birth on cytokine and chemokine responses induced by T‐cell activation during infancy	13
Adeno‐associated viral vectors encoding anti‐P2X7 nanobodies reduce graft‐versus‐host disease in a humanised mouse model	12
Endogenous bystander killing mechanisms enhance the activity of novel FAP‐specific CAR‐T cells against glioblastoma	12
Adaptive immune response to the autoantigen LL ‐37 differentiates atherosclerotic cardiovascular disease phenotypes	10
Mass cytometry analysis reveals altered immune profiles in patients with coronary artery disease	10
Siglec‐1, an easy and contributory inflammation marker in rheumatology	10
Optimised modular anti‐FLAG CAR T cells for solid tumor therapy	10
	10
Immunological insights into gastric polyps: pathogenesis, inflammation and neoplastic potential	9

Genome‐wide association study and polygenic risk scores of eosinophilia in Taiwan	9
Naturally acquired adaptive immunity to Streptococcus pneumoniae is impaired in rheumatoid arthritis patients	9
Inhibitory effect of hydroxychloroquine on glucocorticoid‐induced osteoporosis in lupus therapy	9
	8
Identification of distinct immune signatures in inclusion body myositis by peripheral blood immunophenotyping using machine learning models	8
Human axillary lymph node T follicular helper (Tfh) and Precursor‐Tfh cells exhibit functional flexibility following seasonal influenza vaccination	8
	8
	8
Data standards for single‐cell RNA ‐sequencing of paediatric cancer	8
High KRT17 expression in tumour budding indicates immunologically ‘hot’ tumour budding and predicts good survival in patients with colorectal cancer	8
Skin immunity and inflammation: cellular interactions and communication	8
	8
Robust immunity to influenza vaccination in haematopoietic stem cell transplant recipients following reconstitution of humoral and adaptive immunity	8
A preclinical study of allogeneic CD19 chimeric antigen receptor double‐negative T cells as an off‐the‐shelf immunotherapy drug against B‐cell malignancies	7
Prediction of intravenous immunoglobulin retreatment in children with Kawasaki disease using models combining lymphocyte subset and cytokine profile in an East Asian cohort	7
Hypoxia‐inducible factor‐1α regulates the interleukin‐6 production by B cells in rheumatoid arthritis	7
CD39 expression defines exhausted CD4⁺ T cells associated with poor survival and immune evasion in human gastric cancer	7
Helminths as architects of trained tolerance: implications for human health	7
	7
Fatty acid metabolism—an emerging regulatory node in T‐cell immunometabolism	6
Pulmonary complications post allogeneic haematopoietic stem cell transplant in children	6
A unique cytotoxic CD4 ⁺ T cell‐signature defines critical COVID‐19	6
Infiltrating characteristics and prognostic value of tertiary lymphoid structures in resected gastric neuroendocrine neoplasm patients	6
Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis	6
	6
Neutralising antibody responses to emerging SARS ‐ CoV ‐2 omicron sub‐variants are enhanced in per	6
A comprehensive analysis of the correlation between plasma cytokines/chemokines and tumor immune microenvironment signature influences the response of checkpoint inhibitors in advanced non‐small‐cell	6
The impact of B‐cell reconstitution on mRNA vaccine responses in allogeneic stem cell transplant recipients	6
	6
Long‐term effects of influenza and Bacille Calmette–Guérin vaccination on systemic inflammation	6
	5
Graft CD8 T‐cell‐based risk system predicts survival in antithymocyte globulin‐based myeloablative haploidentical peripheral blood stem cell transplantation	5
Effect of Bacille Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2 and COVID‐19 vaccination	5
Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis	5
Spatial proteomic profiling of tumor and stromal compartments in non‐small‐cell lung cancer identifies signatures associated with overall survival	5
Elucidating novel immune profiles for predicting infection in high‐risk cohorts: a pilot study in patients with relapsed and refractory chronic lymphocytic leukaemia	5
Adoptive T‐cell therapy targeting Epstein–Barr virus as a treatment for multiple sclerosis	5
Serological responses and clinical outcomes following a three‐dose primary COVID‐19 vaccine schedule in kidney transplant recipients and people on dialysis	5
Multi‐omics integration reveals a nonlinear signature that precedes progression of lung fibrosis	5
	5
Antigen‐specific polyfunctional cytotoxic T cells differentiate intraocular from peripheral blood immune responses in posterior uveitis	4
Elevated high‐density lipoprotein levels following acute graft‐versus‐host disease onset: a potential link to T‐cell dysfunction and increased relapse risk	4
Early CRP kinetics to predict long‐term efficacy of first‐line immune‐checkpoint inhibition combination therapies in metastatic renal cell carcinoma: an updated multicentre real‐world experience apply	4
	4
Genetic differences in the HLA region contribute to the variability in SARS‐CoV‐2 vaccine responsiveness of older persons: the Doetinchem Cohort Study	4
High‐dimensional spectral cytometry identifies follicular regulatory CD8 ⁺ T cells in diffuse large B‐cell lymphoma	4
Enhanced and complementary benefits of a nalfurafine and fingolimod combination to treat immune‐driven demyelination	4
Glucocorticoid regulation of the mTORC1 pathway modulates CD4⁺ T cell responses during infection	4
CD8⁺ T cell epitope conservation in emerging H5N1 viruses suggests global protection	4
A characterisation of the immune cells in immunocompetent and immunodeficient mice with orthotopic brain tumors	4

A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases	3
	3
Epstein–Barr virus and multiple sclerosis: the dawn of a new age	3
	3
Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection	3
Clinical, biological and cytometric characteristics of two patients with a homozygous A91V PRF1 mutation	3
Epstein–Barr virus and multiple sclerosis: moving from questions of association to questions of mechanism	3
Roadmap for understanding mechanisms on how Epstein–Barr virus triggers multiple sclerosis and for translating these discoveries in clinical trials	3
Integrated humoral and inflammatory signatures predict outcomes in severe COVID ‐19: a 14‐day longitudinal analysis	3
	3
	3
Integrating mass spectrometry‐based multi‐omic signatures of extracellular vesicles: from discovery to clinical translation	3
	3
Improving thymus implantation for congenital athymia with interleukin‐7	3
Low‐level human memory T and B cells recognising avian influenza hemagglutinins are poorly responsive to existing seasonal influenza vaccines	2
Coexistence of SAPHO syndrome and IgG4‐related disease with Upadacitinib	2
Lymphocyte activation gene 3 served as a potential prognostic and immunological biomarker across various cancer types: a clinical and pan‐cancer analysis	2
From the bench to the clinic: basophils and type 2 epithelial cytokines of thymic stromal lymphopoietin and IL‐33	2
SARS‐CoV‐2‐infected human airway epithelial cell cultures uniquely lack interferon and immediate early gene responses caused by other coronaviruses	2
The role of immunochemotherapy maintenance in metastatic nasopharyngeal carcinoma: insights from a cohort study in an endemic region	2
	2
Targeting CD38 with monoclonal antibodies disrupts key survival pathways in paediatric Burkitt's lymphoma malignant B cells	2
Plasma SARS‐CoV‐2 RNA elimination and RAGE kinetics distinguish COVID‐19 severity	2
Serum AZD7442 (tixagevimab–cilgavimab) concentrations and in vitroIC₅₀ values predict SARS‐CoV‐2 neutralising antibody titres	2
γδ T cell characterisation in the long term after haematopoietic stem cell transplantation and its impact on CMV control and cGVHD severity	2
	2
	2
Inflammatory cytokines as mediators of retinal endothelial barrier dysfunction in non‐infectious uveitis	2
Long‐lasting changes in circulating dendritic cell and monocyte subsets, and altered expression of EMR2, CD97 and EMR3 on these cells in the posttraumatic course	2
Data standards for single‐cell RNA‐sequencing of paediatric cancer	2
	2
Genomic and tumour microenvironmental biomarkers of immune checkpoint inhibitor response in advanced Taiwanese melanoma	2
Prolonged persistence of tissue‐resident memory cells in the upper airway following SARS ‐ CoV ‐2	2
Engineered iPSC ‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapy	2
Enhancing CAR T‐cell therapy manufacturing efficiency through semi‐automated bioprocessing	2
	2
Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures	1
Choice of activation protocol impacts the yield and quality of CAR T cell product, particularly with older individuals	1
High‐dimensional flow cytometry reveals lymphocyte subset populations predictive of chronic lung allograft dysfunction	1
Dissecting infant and maternal antibody repertoires exposes the early onset of infant humoral immunity	1
A phase II study to evaluate the safety and efficacy of anlotinib combined with toripalimab for advanced biliary tract cancer	1
Improving diagnosis in patients with obstetric antiphospholipid syndrome through the evaluation of non‐criteria antibodies	1
Targeting the tumor microenvironment in cholangiocarcinoma to improve immune checkpoint blockade: potential strategies and translational pre‐clinical models	1
The contribution of the CRP/CD64 axis to renal cancer progression by inducing protumor activation of tumor‐associated macrophages	1
Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection	1
Gut metabolites identified in cerebrospinal fluid of genetic interferonopathy support gut–brain endothelial dysfunction	1
Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen‐processing‐presentation machinery and poor patient survival	1
Advances in bacteria‐based drug delivery systems for anti‐tumor therapy	1
Distinct MAIT cell phenotypes associated with sepsis clinical outcome in emergency department patients	1
CD137 deficiency because of two novel biallelic TNFRSF9 mutations in a patient presenting with severe EBV‐associated lymphoproliferative disease	1
Metabolic requirements of CD160 expressing memory‐like NK cells in Gram‐negative bacterial infection	1
Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling	1
Engineered CAR‐T cells targeting the non‐functional P2X purinoceptor 7 (P2X7) receptor as a novel treatment for ovarian cancer	1
Lack of immunogenicity for an influenza‐derived peptide across the HLA‐B44 supertype molecules	1
Chimeric antigen receptor T cells in the fast lane among autoimmune disease therapies	1
An Ad26‐ MVA ‐ BN ‐based therapeutic vaccine targeting HPV16	1
Primary SARS‐CoV‐2 infection in children and adults results in similar Fc‐mediated antibody effector function patterns	1
Long‐term immune changes after COVID ‐19 and the effect of BCG vaccination and latent infections o	1
Immunoglobulin G genetic variation can confound assessment of antibody levels via altered binding to detection reagents	1
Influenza virus infection drives upregulation of CD84 across a broad range of immune cells	1
Plasma EBV quantification is associated with the efficacy of immune checkpoint blockade and disease monitoring in patients with primary pulmonary lymphoepithelioma‐like carcinoma	1
Humoral and cellular immune responses in vaccinated and unvaccinated children following SARS‐CoV‐2 Omicron infection	1
A case of T‐cell‐Epstein–Barr virus‐haemophagocytic lymphohistiocytosis and sustained remission following ruxolitinib therapy	1
Nalmefene enhances the remyelinating ability of nalfurafine when administered therapeutically at very low doses during experimental autoimmune encephalomyelitis	1
Antibody glycosylation correlates with disease progression in SIV‐Mycobacterium tuberculosis coinfected cynomolgus macaques	1
Cellular hierarchy for understanding heterogeneity of acute myeloid leukaemia with t(8;21)/RUNX1‐RUNX1T1	1
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