OOIR: Observatory of International Research

Papers

(The median citation count of Clinical & Translational Immunology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
	97
Circulating cytokine and chemokine patterns associated with cytomegalovirus reactivation after stem cell transplantation	77
The spectrum of B cells in the pathogenesis, diagnosis and therapeutic applications of immunoglobulin G4‐related disease	39
Characteristics of PD‐1⁺CD4⁺ T cells in peripheral blood and synovium of rheumatoid arthritis patients	33
Biomarkers to predict and diagnose pulmonary complications in children post haematopoietic stem cell transplant	31
SARS‐CoV‐2‐associated T‐cell infiltration in the central nervous system	27
	26
Impact of adaptive natural killer cells, KLRC2 genotype and cytomegalovirus reactivation on late mortality in patients with severe COVID‐19 lung disease	26
Mass cytometry analysis reveals altered immune profiles in patients with coronary artery disease	25
Effects of extremely preterm birth on cytokine and chemokine responses induced by T‐cell activation during infancy	23
Targeting BMI‐1 to deplete antibody‐secreting cells in autoimmunity	21
The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation	20
Retrospective analysis of the efficacy of adjuvant cytokine‐induced killer cell immunotherapy combined with chemotherapy in colorectal cancer patients after surgery	20
Validation and performance of a multiplex serology assay to quantify antibody responses following SARS‐CoV‐2 infection or vaccination	19
Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine	19
	19
Endogenous bystander killing mechanisms enhance the activity of novel FAP‐specific CAR‐T cells against glioblastoma	19
	18
Naturally acquired adaptive immunity to Streptococcus pneumoniae is impaired in rheumatoid arthritis patients	17
Inhibitory effect of hydroxychloroquine on glucocorticoid‐induced osteoporosis in lupus therapy	17
	16
Siglec‐1, an easy and contributory inflammation marker in rheumatology	15
Increased mast cell activation in eosinophilic chronic obstructive pulmonary disease	15
Identification of distinct immune signatures in inclusion body myositis by peripheral blood immunophenotyping using machine learning models	15
	14

Robust immunity to influenza vaccination in haematopoietic stem cell transplant recipients following reconstitution of humoral and adaptive immunity	13
	13
Increased amphiregulin expression by CD4⁺ T cells from individuals with asymptomatic Leishmania donovani infection	13
High KRT17 expression in tumour budding indicates immunologically ‘hot’ tumour budding and predicts good survival in patients with colorectal cancer	13
Identification of polo‐like kinase 1 as a therapeutic target in murine lupus	12
Genome‐wide off‐target analyses of CRISPR/Cas9‐mediated T‐cell receptor engineering in primary human T cells	12
Prediction of intravenous immunoglobulin retreatment in children with Kawasaki disease using models combining lymphocyte subset and cytokine profile in an East Asian cohort	12
Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis	11
Immunoregulatory effects of testosterone supplementation combined with exercise training in men with Inclusion Body Myositis: a double‐blind, placebo‐controlled, cross‐over trial	10
Epstein–Barr virus infection, B‐cell dysfunction and other risk factors converge in gut‐associated lymphoid tissue to drive the immunopathogenesis of multiple sclerosis: a hypothesis	10
CD39 expression defines exhausted CD4⁺ T cells associated with poor survival and immune evasion in human gastric cancer	10
A preclinical study of allogeneic CD19 chimeric antigen receptor double‐negative T cells as an off‐the‐shelf immunotherapy drug against B‐cell malignancies	10
	10
Hypoxia‐inducible factor‐1α regulates the interleukin‐6 production by B cells in rheumatoid arthritis	10
	10
Pulmonary complications post allogeneic haematopoietic stem cell transplant in children	9
Importance of crosstalk between the microbiota and the neuroimmune system for tissue homeostasis	9
Spatial proteomic profiling of tumor and stromal compartments in non‐small‐cell lung cancer identifies signatures associated with overall survival	9
Targeting SARS‐CoV‐2 infection through CAR‐T‐like bispecific T cell engagers incorporating ACE2	9
Inflammasome activation: from molecular mechanisms to autoinflammation	9
Effect of washed versus unwashed red blood cells on transfusion‐related immune responses in preterm newborns	9
A unique cytotoxic CD4⁺ T cell‐signature defines critical COVID‐19	9
Adoptive T‐cell therapy targeting Epstein–Barr virus as a treatment for multiple sclerosis	8
Serological responses and clinical outcomes following a three‐dose primary COVID‐19 vaccine schedule in kidney transplant recipients and people on dialysis	8
Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis	8
	8
Multi‐omics integration reveals a nonlinear signature that precedes progression of lung fibrosis	8
Infiltrating characteristics and prognostic value of tertiary lymphoid structures in resected gastric neuroendocrine neoplasm patients	8
	8
Memory stem T cells modified with a redesigned CD30‐chimeric antigen receptor show an enhanced antitumor effect in Hodgkin lymphoma	7
Graft CD8 T‐cell‐based risk system predicts survival in antithymocyte globulin‐based myeloablative haploidentical peripheral blood stem cell transplantation	7
Blood transcriptomics identifies immune signatures indicative of infectious complications in childhood cancer patients with febrile neutropenia	7
Effect of Bacille Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2 and COVID‐19 vaccination	7
Allogeneic haematopoietic stem cell transplantation resets T‐ and B‐cell compartments in sickle cell disease patients	7
Sex‐bias in CD8⁺ T‐cell stemness and exhaustion in cancer	6
	6
Homologous peptides derived from influenza A, B and C viruses induce variable CD8⁺ T cell responses with cross‐reactive potential	6
Glucocorticoid regulation of the mTORC1 pathway modulates CD4⁺ T cell responses during infection	6
Understanding the tumor microenvironment in head and neck squamous cell carcinoma	6
CD8⁺ T cell epitope conservation in emerging H5N1 viruses suggests global protection	6
Glycolipid‐peptide conjugate vaccines elicit CD8⁺ T‐cell responses and prevent breast cancer metastasis	5
	5
Parallel detection of SARS‐CoV‐2 epitopes reveals dynamic immunodominance profiles of CD8⁺ T memory cells in convalescent COVID‐19 donors	5
Early CRP kinetics to predict long‐term efficacy of first‐line immune‐checkpoint inhibition combination therapies in metastatic renal cell carcinoma: an updated multicentre real‐world experience apply	5
Modelling the tumor immune microenvironment for precision immunotherapy	5
SARS‐CoV‐2 triggers complement activation through interactions with heparan sulfate	5
Off‐target effects of bacillus Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2: implications for protection against severe COVID‐19	5
Enhanced and complementary benefits of a nalfurafine and fingolimod combination to treat immune‐driven demyelination	5
A scalable serology solution for profiling humoral immune responses to SARS‐CoV‐2 infection and vaccination	5
The immunopathogenesis of SARS‐CoV‐2 infection in children: diagnostics, treatment and prevention	4

A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases	4
	4
Epstein–Barr virus and multiple sclerosis: the dawn of a new age	4
Epstein–Barr virus and multiple sclerosis: moving from questions of association to questions of mechanism	4
Improving thymus implantation for congenital athymia with interleukin‐7	4
	4
	4
	4
	3
The frequency of Treg subsets distinguishes disease activity in ANCA vasculitis	3
LUNG group 2 innate lymphoid cells as a new adjuvant target to enhance intranasal vaccine efficacy against influenza	3
Lymphocyte activation gene 3 served as a potential prognostic and immunological biomarker across various cancer types: a clinical and pan‐cancer analysis	3
From the bench to the clinic: basophils and type 2 epithelial cytokines of thymic stromal lymphopoietin and IL‐33	3
Diversification and shared features of tumor‐binding antibody repertoires in tumor, sentinel lymph node and blood of three patients with breast cancer	3
Roadmap for understanding mechanisms on how Epstein–Barr virus triggers multiple sclerosis and for translating these discoveries in clinical trials	3
Genomic and tumour microenvironmental biomarkers of immune checkpoint inhibitor response in advanced Taiwanese melanoma	3
Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection	3
	3
SARS‐CoV‐2‐infected human airway epithelial cell cultures uniquely lack interferon and immediate early gene responses caused by other coronaviruses	3
Serum AZD7442 (tixagevimab–cilgavimab) concentrations and in vitroIC₅₀ values predict SARS‐CoV‐2 neutralising antibody titres	2
Targeting CD38 with monoclonal antibodies disrupts key survival pathways in paediatric Burkitt's lymphoma malignant B cells	2
	2
Chimeric antigen receptor T cells in the fast lane among autoimmune disease therapies	2
Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen‐processing‐presentation machinery and poor patient survival	2
Engineered CAR‐T cells targeting the non‐functional P2X purinoceptor 7 (P2X7) receptor as a novel treatment for ovarian cancer	2
Circulating CCR6⁺ILC proportions are lower in multiple sclerosis patients	2
DROSHA but not DICER is required for human haematopoietic stem cell function	2
Anti‐C1q autoantibodies from systemic lupus erythematosus patients enhance CD40–CD154‐mediated inflammation in peripheral blood mononuclear cells in vitro	2
	2
Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection	2
The contribution of the CRP/CD64 axis to renal cancer progression by inducing protumor activation of tumor‐associated macrophages	2
	2
Humoral immunity against SARS‐CoV‐2 variants including omicron in solid organ transplant recipients after three doses of a COVID‐19 mRNA vaccine	2
γδ T cell characterisation in the long term after haematopoietic stem cell transplantation and its impact on CMV control and cGVHD severity	2
	2
Plasma SARS‐CoV‐2 RNA elimination and RAGE kinetics distinguish COVID‐19 severity	2
Inflammatory cytokines as mediators of retinal endothelial barrier dysfunction in non‐infectious uveitis	2
Antibody glycosylation correlates with disease progression in SIV‐Mycobacterium tuberculosis coinfected cynomolgus macaques	2
A case of T‐cell‐Epstein–Barr virus‐haemophagocytic lymphohistiocytosis and sustained remission following ruxolitinib therapy	2
Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures	2
A phase II study to evaluate the safety and efficacy of anlotinib combined with toripalimab for advanced biliary tract cancer	1
Allogeneic CD20‐targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B‐cell lymphoma models	1
Probabilistic classification of anti‐SARS‐CoV‐2 antibody responses improves seroprevalence estimates	1
Inhibition of renal fibrosis with a human CXCL9‐derived glycosaminoglycan‐binding peptide	1
Plasma EBV quantification is associated with the efficacy of immune checkpoint blockade and disease monitoring in patients with primary pulmonary lymphoepithelioma‐like carcinoma	1
Unremitting pro‐inflammatory T‐cell phenotypes, and macrophage activity, following paediatric burn injury	1
Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality	1
Cerebrospinal fluid YKL‐40 level evolution is associated with autoimmune encephalitis remission	1
A new flow cytometry assay identifies recipient IgG subtype antibodies binding donor cells: increasing donor availability for highly sensitised patients	1
Metabolic requirements of CD160 expressing memory‐like NK cells in Gram‐negative bacterial infection	1
Advances in bacteria‐based drug delivery systems for anti‐tumor therapy	1
Early‐like differentiation status of systemic PD‐1⁺CD8⁺ T cells predicts PD‐1 blockade outcome in non‐small cell lung cancer	1
Circulating CD8⁺ mucosal‐associated invariant T cells correlate with improved treatment responses and overall survival in anti‐PD‐1‐treated melanoma patients	1
Primary SARS‐CoV‐2 infection in children and adults results in similar Fc‐mediated antibody effector function patterns	1
From bedside to bench: how existing therapies inform the relationship between Epstein–Barr virus and multiple sclerosis	1
Molecular and cellular mechanisms of itch and pain in atopic dermatitis and implications for novel therapeutics	1
YTHDF2 promotes temozolomide resistance in glioblastoma by activation of the Akt and NF‐κB signalling pathways via inhibiting EPHB3 and TNFAIP3	1
G‐CSF induces CD15⁺ CD14⁺ cells from granulocytes early in the physiological environment of pregnancy and the cancer immunosuppressive microenvironment	1
Improving diagnosis in patients with obstetric antiphospholipid syndrome through the evaluation of non‐criteria antibodies	1
Distinct MAIT cell phenotypes associated with sepsis clinical outcome in emergency department patients	1
Humoral and cellular immune responses in vaccinated and unvaccinated children following SARS‐CoV‐2 Omicron infection	1
Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling	1
CD137 deficiency because of two novel biallelic TNFRSF9 mutations in a patient presenting with severe EBV‐associated lymphoproliferative disease	1
Detailed bladder cancer immunoprofiling reveals new clues for immunotherapeutic strategies	1
Choice of activation protocol impacts the yield and quality of CAR T cell product, particularly with older individuals	1
Immunoglobulin G genetic variation can confound assessment of antibody levels via altered binding to detection reagents	1
A peptoid interleukin‐15 receptor antagonist suppresses inflammation and arthritis in mice	1