Cancer & Metabolism

Papers
(The TQCC of Cancer & Metabolism is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition102
GCN2-SLC7A11 axis coordinates autophagy, cell cycle and apoptosis and regulates cell growth in retinoblastoma upon arginine deprivation65
The classification of obesity based on metabolic status redefines the readmission of non-Hodgkin’s lymphoma—an observational study48
FOXO3a/miR-4259-driven LDHA expression as a key mechanism of gemcitabine sensitivity in pancreatic ductal adenocarcinoma42
Ketomimetic nutrients remodel the glycocalyx and trigger a metabolic defense in breast cancer cells36
Magnetospirillum magneticum triggers apoptotic pathways in human breast cancer cells31
Metabolic convergence on lipogenesis in RAS, BCR-ABL, and MYC-driven lymphoid malignancies31
Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response31
ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma31
Circulating metabolome landscape in Lynch syndrome26
Glycemic status, insulin resistance, and mortality from lung cancer among individuals with and without diabetes25
Autofluorescence imaging of endogenous metabolic cofactors in response to cytokine stimulation of classically activated macrophages25
Steatohepatitis-induced vascular niche alterations promote melanoma metastasis21
Correction: Cholesterol reprograms glucose and lipid metabolism to promote proliferation in colon cancer cells21
Global metabolic alterations in colorectal cancer cells during irinotecan-induced DNA replication stress21
CYP19A1 regulates chemoresistance in colorectal cancer through modulation of estrogen biosynthesis and mitochondrial function19
Disrupting Na+ ion homeostasis and Na+/K+ ATPase activity in breast cancer cells directly modulates glycolysis in vitro and in vivo18
ATM inhibition blocks glucose metabolism and amplifies the sensitivity of resistant lung cancer cell lines to oncogene driver inhibitors18
Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics17
Characterizing OXPHOS inhibitor-mediated alleviation of hypoxia using high-throughput live cell-imaging17
DHODH and cancer: promising prospects to be explored16
Long-acting Erwinia chrysanthemi, Pegcrisantaspase, induces alternate amino acid biosynthetic pathways in a preclinical model of pancreatic ductal adenocarcinoma15
Comparative polar and lipid plasma metabolomics differentiate KSHV infection and disease states15
Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles15
Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 114
Integration of global metabolomics and lipidomics approaches reveals the molecular mechanisms and the potential biomarkers for postoperative recurrence in early-stage cholangiocarcinoma14
Lactate metabolism in clonal plasma cells and its therapeutic implications in multiple myeloma patients with elevated serum LDH levels14
Correction: STEAP4 inhibits cisplatin-induced chemotherapy resistance through suppressing PI3K/AKT in hepatocellular carcinoma14
Altered acetyl-CoA metabolism presents a new potential immunotherapy target in the obese lung microenvironment14
BMP4 upregulates glycogen synthesis through the SMAD/SLC2A1 (GLUT1) signaling axis in hepatocellular carcinoma (HCC) cells14
STEAP4 inhibits cisplatin-induced chemotherapy resistance through suppressing PI3K/AKT in hepatocellular carcinoma13
Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin12
Statin use as a moderator on the association between metformin and breast cancer risk in women with type 2 diabetes mellitus12
Brief report: The uricase mutation in humans increases our risk for cancer growth12
Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 cells12
Unveiling the powerhouse: ASCL1-driven small cell lung cancer is characterized by higher numbers of mitochondria and enhanced oxidative phosphorylation12
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