Cancer & Metabolism

Papers
(The TQCC of Cancer & Metabolism is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
The classification of obesity based on metabolic status redefines the readmission of non-Hodgkin’s lymphoma—an observational study108
FOXO3a/miR-4259-driven LDHA expression as a key mechanism of gemcitabine sensitivity in pancreatic ductal adenocarcinoma74
A role of arginase-1-expressing myeloid cells in cachexia51
Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition46
GCN2-SLC7A11 axis coordinates autophagy, cell cycle and apoptosis and regulates cell growth in retinoblastoma upon arginine deprivation38
Ketomimetic nutrients remodel the glycocalyx and trigger a metabolic defense in breast cancer cells35
ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma30
Measurement of mitochondria amount and clearance using flow cytometry: effect of mitophagy inhibitors in leukemia cells29
Lactate dehydrogenase A-coupled NAD+ regeneration is critical for acute myeloid leukemia cell survival28
Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response26
Glycemic status, insulin resistance, and mortality from lung cancer among individuals with and without diabetes26
Autofluorescence imaging of endogenous metabolic cofactors in response to cytokine stimulation of classically activated macrophages26
Magnetospirillum magneticum triggers apoptotic pathways in human breast cancer cells25
Circulating metabolome landscape in Lynch syndrome24
Transcriptome-driven constraint-based modelling reveals metabolic targets for ovarian cancer23
Correction: Cholesterol reprograms glucose and lipid metabolism to promote proliferation in colon cancer cells23
Steatohepatitis-induced vascular niche alterations promote melanoma metastasis23
Identification and impact of microbiota-derived metabolites in ascites of ovarian and gastrointestinal cancer22
In vivo characterization of the redox balance in IDH-wildtype glioblastomas: a J-difference edited MEGA-sLASER MRS study at 3T22
ATM inhibition blocks glucose metabolism and amplifies the sensitivity of resistant lung cancer cell lines to oncogene driver inhibitors21
Global metabolic alterations in colorectal cancer cells during irinotecan-induced DNA replication stress19
Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling19
POU2F1 drives cholesterol biosynthesis and lipid remodeling through the DHCR24/ELOVL2 axis in endometrial cancer18
Sustained reductions in valine and isoleucine mediate anti-cancer pharmacological effects of inhibiting amino acid transporter LAT1 in cancer cells17
CYP19A1 regulates chemoresistance in colorectal cancer through modulation of estrogen biosynthesis and mitochondrial function17
Characterizing OXPHOS inhibitor-mediated alleviation of hypoxia using high-throughput live cell-imaging16
Pharmacological inhibition of Peroxisome Proliferation-Activated Receptor Delta (PPARδ) imparts selective leukemia cell death16
Disrupting Na+ ion homeostasis and Na+/K+ ATPase activity in breast cancer cells directly modulates glycolysis in vitro and in vivo16
Correction: STEAP4 inhibits cisplatin-induced chemotherapy resistance through suppressing PI3K/AKT in hepatocellular carcinoma15
Long-acting Erwinia chrysanthemi, Pegcrisantaspase, induces alternate amino acid biosynthetic pathways in a preclinical model of pancreatic ductal adenocarcinoma12
The integration of single-cell and metabolomics reveals the increase of oxidative phosphorylation during the liver metastasis of colorectal cancer12
PFKFB4 promotes M2 polarization of tumor-associated macrophages through aerobic glycolysis-mediated modification of histone H3K18 lactylation in hepatocellular carcinoma11
BMP4 upregulates glycogen synthesis through the SMAD/SLC2A1 (GLUT1) signaling axis in hepatocellular carcinoma (HCC) cells11
Comparative polar and lipid plasma metabolomics differentiate KSHV infection and disease states11
Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 110
Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles10
Lactate metabolism in clonal plasma cells and its therapeutic implications in multiple myeloma patients with elevated serum LDH levels10
Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 cells10
Altered acetyl-CoA metabolism presents a new potential immunotherapy target in the obese lung microenvironment10
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