Cancer & Metabolism

Papers
(The TQCC of Cancer & Metabolism is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
The diversity and breadth of cancer cell fatty acid metabolism121
DHODH and cancer: promising prospects to be explored80
Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI72
ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma49
Pyruvate carboxylase and cancer progression48
Mitochondrial metabolism as a target for acute myeloid leukemia treatment40
Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines34
Lipopolysaccharide promotes metastasis via acceleration of glycolysis by the nuclear factor-κB/snail/hexokinase3 signaling axis in colorectal cancer30
SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice28
A small-molecule pan-class I glucose transporter inhibitor reduces cancer cell proliferation in vitro and tumor growth in vivo by targeting glucose-based metabolism27
Treatment of glioblastoma multiforme with “classic” 4:1 ketogenic diet total meal replacement25
Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer25
Dynamic regulation of mitochondrial pyruvate metabolism is necessary for orthotopic pancreatic tumor growth24
RNF115 promotes lung adenocarcinoma through Wnt/β-catenin pathway activation by mediating APC ubiquitination21
ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism21
Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover21
The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer21
Pharmacological activation of pyruvate kinase M2 reprograms glycolysis leading to TXNIP depletion and AMPK activation in breast cancer cells21
MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation21
Integrative analysis of plasma metabolomics and proteomics reveals the metabolic landscape of breast cancer20
Mass spectrometry imaging of L-[ring-13C6]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma20
In vivo assessment of glutamine anaplerosis into the TCA cycle in human pre-malignant and malignant clonal plasma cells17
Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness16
Tumor suppressor SMAR1 regulates PKM alternative splicing by HDAC6-mediated deacetylation of PTBP116
Sulfasalazine modifies metabolic profiles and enhances cisplatin chemosensitivity on cholangiocarcinoma cells in in vitro and in vivo models16
Inflammatory metabolic profile of South African patients with prostate cancer16
Mutant IDH and non-mutant chondrosarcomas display distinct cellular metabolomes15
13C tracer analysis suggests extensive recycling of endogenous CO2 in vivo14
PEPCK-M recoups tumor cell anabolic potential in a PKC-ζ-dependent manner13
Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma13
The PD-L1 metabolic interactome intersects with choline metabolism and inflammation13
Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM1513
Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics13
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