Cancer & Metabolism

Papers
(The median citation count of Cancer & Metabolism is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
The diversity and breadth of cancer cell fatty acid metabolism106
Fructose contributes to the Warburg effect for cancer growth74
DHODH and cancer: promising prospects to be explored69
Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI61
Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer60
Tumor-associated collagen signatures: pushing tumor boundaries40
Pyruvate carboxylase and cancer progression36
ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma31
Mitochondrial metabolism as a target for acute myeloid leukemia treatment30
Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines25
SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice25
Modulating pyrimidine ribonucleotide levels for the treatment of cancer24
Lipopolysaccharide promotes metastasis via acceleration of glycolysis by the nuclear factor-κB/snail/hexokinase3 signaling axis in colorectal cancer23
A small-molecule pan-class I glucose transporter inhibitor reduces cancer cell proliferation in vitro and tumor growth in vivo by targeting glucose-based metabolism22
Dynamic regulation of mitochondrial pyruvate metabolism is necessary for orthotopic pancreatic tumor growth22
Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model22
Metabolite AutoPlotter - an application to process and visualise metabolite data in the web browser22
Treatment of glioblastoma multiforme with “classic” 4:1 ketogenic diet total meal replacement21
Metformin sensitizes therapeutic agents and improves outcome in pre-clinical and clinical diffuse large B-cell lymphoma20
Metabolic regulation of calcium pumps in pancreatic cancer: role of phosphofructokinase-fructose-bisphosphatase-3 (PFKFB3)20
Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer19
Mass spectrometry imaging of L-[ring-13C6]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma18
Metabolic plasticity imparts erlotinib-resistance in pancreatic cancer by upregulating glucose-6-phosphate dehydrogenase18
Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover17
The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer17
Pharmacological activation of pyruvate kinase M2 reprograms glycolysis leading to TXNIP depletion and AMPK activation in breast cancer cells16
In vivo assessment of glutamine anaplerosis into the TCA cycle in human pre-malignant and malignant clonal plasma cells15
ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism15
Inflammatory metabolic profile of South African patients with prostate cancer15
Tumor suppressor SMAR1 regulates PKM alternative splicing by HDAC6-mediated deacetylation of PTBP114
Sulfasalazine modifies metabolic profiles and enhances cisplatin chemosensitivity on cholangiocarcinoma cells in in vitro and in vivo models14
Metabolic plasticity of IDH1-mutant glioma cell lines is responsible for low sensitivity to glutaminase inhibition14
RNF115 promotes lung adenocarcinoma through Wnt/β-catenin pathway activation by mediating APC ubiquitination14
Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness14
MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation13
PHGDH supports liver ceramide synthesis and sustains lipid homeostasis13
GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase12
Estrogen-related receptor alpha directly binds to p53 and cooperatively controls colon cancer growth through the regulation of mitochondrial biogenesis and function12
PEPCK-M recoups tumor cell anabolic potential in a PKC-ζ-dependent manner11
Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells11
Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM1511
Integration of global metabolomics and lipidomics approaches reveals the molecular mechanisms and the potential biomarkers for postoperative recurrence in early-stage cholangiocarcinoma11
3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation11
Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics11
13C tracer analysis suggests extensive recycling of endogenous CO2 in vivo11
Integrative analysis of plasma metabolomics and proteomics reveals the metabolic landscape of breast cancer11
Mutant IDH and non-mutant chondrosarcomas display distinct cellular metabolomes11
The PD-L1 metabolic interactome intersects with choline metabolism and inflammation11
Deficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis11
Disruption of redox homeostasis for combinatorial drug efficacy in K-Ras tumors as revealed by metabolic connectivity profiling10
Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity10
Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells10
Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma10
Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate9
Common biochemical properties of metabolic genes recurrently dysregulated in tumors9
An iron chelation-based combinatorial anticancer therapy comprising deferoxamine and a lactate excretion inhibitor inhibits the proliferation of cancer cells9
Novel humanized monoclonal antibodies for targeting hypoxic human tumors via two distinct extracellular domains of carbonic anhydrase IX9
The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trial8
TNF-α differentially modulates subunit levels of respiratory electron transport complexes of ER/PR +ve/−ve breast cancer cells to regulate mitochondrial complex activity and tumorigenic potential8
Prognostic value of metabolic tumor volume and total lesion glycolysis on preoperative 18F-FDG PET/CT in patients with localized primary gastrointestinal stromal tumors8
Detection of glucose-derived d- and l-lactate in cancer cells by the use of a chiral NMR shift reagent8
Isotope tracing reveals distinct substrate preference in murine melanoma subtypes with differing anti-tumor immunity8
Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 cells8
Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas8
Global metabolic alterations in colorectal cancer cells during irinotecan-induced DNA replication stress8
The effect of metabolic syndrome on head and neck cancer incidence risk: a population-based prospective cohort study8
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