Cancer & Metabolism

Papers
(The median citation count of Cancer & Metabolism is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
The diversity and breadth of cancer cell fatty acid metabolism121
DHODH and cancer: promising prospects to be explored80
Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI72
ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma49
Pyruvate carboxylase and cancer progression48
Mitochondrial metabolism as a target for acute myeloid leukemia treatment40
Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines34
Lipopolysaccharide promotes metastasis via acceleration of glycolysis by the nuclear factor-κB/snail/hexokinase3 signaling axis in colorectal cancer30
SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice28
A small-molecule pan-class I glucose transporter inhibitor reduces cancer cell proliferation in vitro and tumor growth in vivo by targeting glucose-based metabolism27
Treatment of glioblastoma multiforme with “classic” 4:1 ketogenic diet total meal replacement25
Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer25
Dynamic regulation of mitochondrial pyruvate metabolism is necessary for orthotopic pancreatic tumor growth24
RNF115 promotes lung adenocarcinoma through Wnt/β-catenin pathway activation by mediating APC ubiquitination21
ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism21
Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover21
The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer21
Pharmacological activation of pyruvate kinase M2 reprograms glycolysis leading to TXNIP depletion and AMPK activation in breast cancer cells21
MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation21
Integrative analysis of plasma metabolomics and proteomics reveals the metabolic landscape of breast cancer20
Mass spectrometry imaging of L-[ring-13C6]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma20
In vivo assessment of glutamine anaplerosis into the TCA cycle in human pre-malignant and malignant clonal plasma cells17
Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness16
Tumor suppressor SMAR1 regulates PKM alternative splicing by HDAC6-mediated deacetylation of PTBP116
Sulfasalazine modifies metabolic profiles and enhances cisplatin chemosensitivity on cholangiocarcinoma cells in in vitro and in vivo models16
Inflammatory metabolic profile of South African patients with prostate cancer16
Mutant IDH and non-mutant chondrosarcomas display distinct cellular metabolomes15
13C tracer analysis suggests extensive recycling of endogenous CO2 in vivo14
PEPCK-M recoups tumor cell anabolic potential in a PKC-ζ-dependent manner13
Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma13
The PD-L1 metabolic interactome intersects with choline metabolism and inflammation13
Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM1513
Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics13
Deficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis12
3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation12
Estrogen-related receptor alpha directly binds to p53 and cooperatively controls colon cancer growth through the regulation of mitochondrial biogenesis and function12
GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase12
Integration of global metabolomics and lipidomics approaches reveals the molecular mechanisms and the potential biomarkers for postoperative recurrence in early-stage cholangiocarcinoma12
Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity11
TNF-α differentially modulates subunit levels of respiratory electron transport complexes of ER/PR +ve/−ve breast cancer cells to regulate mitochondrial complex activity and tumorigenic potential11
Novel humanized monoclonal antibodies for targeting hypoxic human tumors via two distinct extracellular domains of carbonic anhydrase IX11
Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells11
Global metabolic alterations in colorectal cancer cells during irinotecan-induced DNA replication stress11
The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trial11
Isotope tracing reveals distinct substrate preference in murine melanoma subtypes with differing anti-tumor immunity11
Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas10
Brief report: The uricase mutation in humans increases our risk for cancer growth10
Detection of glucose-derived d- and l-lactate in cancer cells by the use of a chiral NMR shift reagent10
Prognostic value of metabolic tumor volume and total lesion glycolysis on preoperative 18F-FDG PET/CT in patients with localized primary gastrointestinal stromal tumors10
Tamoxifen induces radioresistance through NRF2-mediated metabolic reprogramming in breast cancer10
Blocking lncRNA-SNHG16 sensitizes gastric cancer cells to 5-Fu through targeting the miR-506-3p-PTBP1-mediated glucose metabolism9
Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate9
The effect of metabolic syndrome on head and neck cancer incidence risk: a population-based prospective cohort study9
An iron chelation-based combinatorial anticancer therapy comprising deferoxamine and a lactate excretion inhibitor inhibits the proliferation of cancer cells9
Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 cells9
Dual inhibition of IDO1/TDO2 enhances anti-tumor immunity in platinum-resistant non-small cell lung cancer7
PDK1- and PDK2-mediated metabolic reprogramming contributes to the TGFβ1-promoted stem-like properties in head and neck cancer7
Intracellular arginine-dependent translation sensor reveals the dynamics of arginine starvation response and resistance in ASS1-negative cells7
Safety, tolerability, and effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in combination with standard chemotherapy for patients with advanced, inoperable pancreat7
Obesity and breast cancer prognosis: pre-diagnostic anthropometric measures in relation to patient, tumor, and treatment characteristics7
Aglycemic growth enhances carbohydrate metabolism and induces sensitivity to menadione in cultured tumor-derived cells7
Data-driven identification of plasma metabolite clusters and metabolites of interest for potential detection of early-stage non-small cell lung cancer cases versus cancer-free controls7
Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin6
Scaffold-mediated switching of lymphoma metabolism in culture6
A feedback loop of PPP and PI3K/AKT signal pathway drives regorafenib-resistance in HCC6
Arginase-1 inhibition reduces migration ability and metastatic colonization of colon cancer cells6
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