OOIR: Observatory of International Research

Papers

(The H4-Index of Translational Neurodegeneration is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes	890
Current understanding of metal ions in the pathogenesis of Alzheimer’s disease	214
Brain-derived neurotrophic factor in Alzheimer’s disease and its pharmaceutical potential	122
Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration	120
The emerging roles of vacuolar-type ATPase-dependent Lysosomal acidification in neurodegenerative diseases	90
Peripheral clearance of brain-derived Aβ in Alzheimer's disease: pathophysiology and therapeutic perspectives	81
Freezing of gait in Parkinson’s disease: pathophysiology, risk factors and treatments	78
Immunotherapy for Alzheimer’s disease: targeting β-amyloid and beyond	78
COVID-19 and Alzheimer’s disease: how one crisis worsens the other	72
Advances in the development of new biomarkers for Alzheimer’s disease	68
The role of pathological tau in synaptic dysfunction in Alzheimer’s diseases	66
The human olfactory system in two proteinopathies: Alzheimer’s and Parkinson’s diseases	62
Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation	57
The compensatory phenomenon of the functional connectome related to pathological biomarkers in individuals with subjective cognitive decline	47
Cross-talks among GBA mutations, glucocerebrosidase, and α-synuclein in GBA-associated Parkinson’s disease and their targeted therapeutic approaches: a comprehensive review	47
Extensive frontal focused ultrasound mediated blood–brain barrier opening for the treatment of Alzheimer’s disease: a proof-of-concept study	46
Alpha-synuclein seeding shows a wide heterogeneity in multiple system atrophy	44
TLR2 and TLR4 in Parkinson’s disease pathogenesis: the environment takes a toll on the gut	42
Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria	41
The relationships of vitamin D, vitamin D receptor gene polymorphisms, and vitamin D supplementation with Parkinson’s disease	40
Gut microbiome, cognitive function and brain structure: a multi-omics integration analysis	39
Multitasking guardian of mitochondrial quality: Parkin function and Parkinson’s disease	39
A new paradigm for diagnosis of neurodegenerative diseases: peripheral exosomes of brain origin	39
Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies	38
Several miRNAs derived from serum extracellular vesicles are potential biomarkers for early diagnosis and progression of Parkinson’s disease	38

Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease: pathologic roles and therapeutic implications	37
Increased prediction value of biomarker combinations for the conversion of mild cognitive impairment to Alzheimer’s dementia	37
Integrated lipidomics and proteomics network analysis highlights lipid and immunity pathways associated with Alzheimer’s disease	37
Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases	36
Advances in retina imaging as potential biomarkers for early diagnosis of Alzheimer’s disease	36
Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease	36
Maintaining the balance of TDP-43, mitochondria, and autophagy: a promising therapeutic strategy for neurodegenerative diseases	33
Transplantation of bone marrow mesenchymal stem cells improves cognitive deficits and alleviates neuropathology in animal models of Alzheimer’s disease: a meta-analytic review on potential mechanisms	32
CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers	32