Biology Open

Article	Citations
Cardiac myosin super relaxation (SRX): a perspective on fundamental biology, human disease and therapeutics	50
Reissner fibre-induced urotensin signalling from cerebrospinal fluid-contacting neurons prevents scoliosis of the vertebrate spine	40
Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease	38
Starvation causes female-to-male sex reversal through lipid metabolism in the teleost fish, medaka (Olyzias latipes)	30
BMP-treated human embryonic stem cells transcriptionally resemble amnion cells in the monkey embryo	30
Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice	26
Quantified growth of the human embryonic heart	24
Efficient and crucial quality control of HAP1 cell ploidy status	24
Uncharted routes: exploring the relevance of auxin movement via plasmodesmata	22
Publishing ethics in the era of paper mills	19
A versatile, automated and high-throughput drug screening platform for zebrafish embryos	19
Three-dimensional model of glioblastoma by co-culturing tumor stem cells with human brain organoids	18
RNA-Seq reveals changes in human placental metabolism, transport and endocrinology across the first–second trimester transition	17
Genome wide association study for the identification of genes associated with tail fat deposition in Chinese sheep breeds	16
Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research	16
Local adaptation in thermal tolerance for a tropical butterfly across ecotone and rainforest habitats	15
Developmental disorders caused by haploinsufficiency of transcriptional regulators: a perspective based on cell fate determination	15
Motion: enhancing signals and concealing cues	14
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane	14
Redundant functions of the SLC5A transporters Rumpel, Bumpel, and Kumpel in ensheathing glial cells	14
Auxin confers protection against ER stress in Caenorhabditis elegans	13
20-hydroxyecdysone (20E) signaling regulates amnioserosa morphogenesis during Drosophila dorsal closure: EcR modulates gene expression in a complex with the AP-1 subunit, Jun	13
Altered germline cyst formation and oogenesis in Tex14 mutant mice	13
The SARS-CoV-2 receptor and other key components of the Renin-Angiotensin-Aldosterone System related to COVID-19 are expressed in enterocytes in larval zebrafish	13
Bisphenol A promotes stress granule assembly and modulates the integrated stress response	12

Mechanical and energetic determinants of impaired gait following stroke: segmental work and pendular energy transduction during treadmill walking	12
The LRRK2 signaling network converges on a centriolar phospho-Rab10/RILPL1 complex to cause deficits in centrosome cohesion and cell polarization	12
Dynamic neurotransmitter specific transcription factor expression profiles during Drosophila development	12
A Caenorhabditis elegans behavioral assay distinguishes early stage prostate cancer patient urine from controls	12
Stability of amino acids and related amines in human serum under different preprocessing and pre-storage conditions based on iTRAQ®-LC-MS/MS	11
Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis	11
Specificity, redundancy and dosage thresholds among gata4/5/6 genes during zebrafish cardiogenesis	11
Neural crest cells require Meis2 for patterning the mandibular arch via the Sonic hedgehog pathway	11
Beyond bold versus shy: Zebrafish exploratory behavior falls into several behavioral clusters and is influenced by strain and sex	11
Gap junctions: historical discoveries and new findings in the C aenorhabditis  elegans nervous system	11
Efficient induction and sustenance of pluripotent stem cells from bovine somatic cells	11
Shifting away from the business-as-usual approach to research conferences	11
CD47 differentially regulates white and brown fat function	10
Auxin treatment increases lifespan in Caenorhabditis elegans	10
Conditional targeting of phosphatidylserine decarboxylase to lipid droplets	10
KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance	9
Connecting different heart diseases through intercellular communication	9
Eye morphogenesis in the blind Mexican cavefish	9
Presynaptic HCN channels constrain GABAergic synaptic transmission in pyramidal cells of the medial prefrontal cortex	9
Compartment and cell-type specific hypoxia responses in the developing Drosophila brain	9
High glucose induces Nox4 expression and podocyte apoptosis through the Smad3/ezrin/PKA pathway	8
Convergent acoustic community structure in South Asian dry and wet grassland birds	8
Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing	8
The Drosophila orthologue of the primary ciliary dyskinesia-associated gene, DNAAF3, is required for axonemal dynein assembly	8
Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world	8
Muscle forces and the demands of human walking	8
Biophysical and biochemical properties of Deup1 self-assemblies: a potential driver for deuterosome formation during multiciliogenesis	8
Computational anatomy and geometric shape analysis enables analysis of complex craniofacial phenotypes in zebrafish	8
Sleep-length differences are associated with altered longevity in the fruit fly Drosophila melanogaster	8
A glucose-supplemented diet enhances gut barrier integrity in Drosophila	8
Quantitative analysis of signaling responses during mouse primordial germ cell specification	8
Design of a 3D printed, motorized, uniaxial cell stretcher for microscopic and biochemical analysis of mechanotransduction	7
Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic transport, γH2AX accumulation, and Bax/Bak-dependence	7
Perinatal exposure to synergistic multiple stressors leads to cellular and behavioral deficits mimicking Schizophrenia-like pathology	7
Downregulated brain and muscle aryl hydrocarbon receptor nuclear translocator-like protein-1 inhibits osteogenesis of BMSCs through p53 in type 2 diabetes mellitus	7
Apoptosis is a generator of Wnt-dependent regeneration and homeostatic cell renewal in the ascidian Ciona	7
Validating accelerometry-derived proxies of energy expenditure using the doubly labelled water method in the smallest penguin species	7
Pigment pattern morphospace ofDaniofishes: evolutionary diversification and mutational effects	7
Transduction of rat and human adipose-tissue derived mesenchymal stromal cells by adeno-associated viral vector serotype DJ	7
Basement membrane dynamics and mechanics in tissue morphogenesis	7
Src family kinases inhibit differentiation of intestinal epithelial cells through the Hippo effector YAP1	7
Heart rate and startle responses in diving, captive harbour porpoises (Phocoena phocoena) exposed to transient noise and sonar	7
RGS5: a novel role as a hypoxia-responsive protein that suppresses chemokinetic and chemotactic migration in brain pericytes	7
The importance of considering regulatory domains in genome-wide analyses – the nearest gene is often wrong!	7
Requirement for STAT3 and its target, TFCP2L1, in self-renewal of naïve pluripotent stem cells in vivo and in vitro	6
A mouse model displays host and bacterial strain differences in Aerococcus urinae urinary tract infection	6
Lifespan and ROS levels in different Drosophila melanogaster strains after 24 h hypoxia exposure	6
Postnatal expression profiles of atypical cadherin FAT1 suggest its role in autism	6
Associative learning in larval and adultDrosophilais impaired by the dopamine-synthesis inhibitor 3-Iodo-L-tyrosine	6
Modulation of retinoid-X-receptors differentially regulates expression of apolipoprotein genes apoc1 and apoeb by zebrafish microglia	6

Energetics of whiskered bats in comparison to other bats of the family Vespertilionidae	6
Variations in oxidative stress and antioxidant defense level during different phases of hibernation in common Asian toad,Duttaphrynus melanostictus	6
Zebrafish models of alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye	6
Interaction between Discs large and Pins/LGN/GPSM2: a comparison across species	6
Alone in a crowd: effect of a nonfunctional lateral line on expression of the social hormone parathyroid hormone 2	6
Actin cytoskeleton in angiogenesis	6
A guide to preprinting for early-career researchers	6
Mutations in the splicing regulator Prp31 lead to retinal degeneration in Drosophila	6
A nematode-derived, mitochondrial stress signaling-regulated peptide exhibits broad antibacterial activity	6
The dorsal blastopore lip is a source of signals inducing planar cell polarity in the Xenopus neural plate	6
Regulation of NANOG and SOX2 expression by activin A and a canonical WNT agonist in bovine embryonic stem cells and blastocysts	6
Tissue-specific transcriptome profiles identify functional differences key to understanding whole plant response to life in variable salinity	6
Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs	6
Effect of heterogeneous substrate adhesivity of follower cells on speed and tension profile of leader cells in primary keratocyte collective cell migration	6
A kinase translocation reporter reveals real-time dynamics of ERK activity in Drosophila	6
MonitoringSchizosaccharomyces pombegenome stress by visualizing end-binding protein Ku	6
Influence of weighted downhill running training on serial sarcomere number and work loop performance in the rat soleus	6
Responses to transient receptor potential (TRP) channel agonists inChlamydomonas reinhardtii	6
MicroRNA-9-5p inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting peroxisome proliferator-activated receptor β	6
Phenotype assessment for neurodegenerative murine models with ataxia and application to Niemann–Pick disease, type C1	5
EPCAM and TROP2 share a role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice	5
Oviductal fluid counterbalances the negative effect of high temperature on sperm in an ectotherm model	5
Developmental expression patterns of toolkit genes in male accessory gland ofDrosophilaparallels those of mammalian prostate	5
Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia	5
Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect	5
Soluble receptor for advanced glycation end products protects from ischemia- and reperfusion-induced acute kidney injury	5
A Year at the Forefront of Engineering Photosynthesis	5
Research culture: science from bench to society	5
Vitamin D receptor absence does not enhance intestinal tumorigenesis in ApcPirc/+rats	5
Serotonin: an overlooked regulator of endocytosis and endosomal sorting?	5
Phospholipids containing ether-bound hydrocarbon-chains are essential for efficient phagocytosis and neutral lipids of the ester-type perturb development in Dictyostelium	5
Three functional polymorphisms in CCDC170 were associated with osteoporosis phenotype	5
A fully automated deep learning pipeline for high-throughput colony segmentation and classification	5
Orally administered branaplam does not impact neurogenesis in juvenile mice, rats, and dogs	5
Antimicrobial peptide expression in the cockroach gut during enterobacterial infection is specific and influenced by type III secretion	5
The uncoating of EV71 in mature late endosomes requires CD-M6PR	5
Fracture biomechanics influence local and systemic immune responses in a murine fracture-related infection model	5
Exocrine pancreas proteases regulate β-cell proliferation in zebrafish ciliopathy models and in murine systems	5
A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe syndrome	5
Mummichog gill and operculum exhibit functionally consistent claudin-10 paralog profiles and Claudin-10c hypersaline response	5
Development of a highly pulmonary metastatic orthotopic renal cell carcinoma murine model	5
Functionally distinct roles for T and Tbx6 during mouse development	5
Influence of maternal diet on offspring survivorship, growth, and reproduction in a sheetweb spider	5
Smoking flies: testing the effect of tobacco cigarettes on heart function ofDrosophila melanogaster	5
What drives mixed-species shoaling among wild zebrafish? The roles of predators, food access, abundance of conspecifics and familiarity	4
Insights into in vivo adipocyte differentiation through cell-specific labeling in zebrafish	4
Single-cell sequencing reveals the potential oncogenic expression atlas of human iPSC-derived cardiomyocytes	4
DNMT1 is a negative regulator of osteogenesis	4
A node-based informed modularity strategy to identify organizational modules in anatomical networks	4
Dissecting dynamics and differences of selective pressures in the evolution of human pigmentation	4
Interdomain interactions regulate the localization of a lipid transfer protein at ER-PM contact sites	4
Minimal functional domains of the core polarity regulator Dlg	4
Effects of mechanical stimulation on metabolomic profiles of SW1353 chondrocytes: shear and compression	4
Metabolic scaling of fire ants (Solenopsis invicta) engaged in collective behaviors	4
Light-sheet microscopy reveals dorsoventral asymmetric membrane dynamics ofAmoeba proteusduring pressure-driven locomotion	4
Mapping the transcriptomic changes of endothelial compartment in human hippocampus across aging and mild cognitive impairment	4
The thermal dependence and molecular basis of physiological color change in Takydromus septentrionalis (Lacertidae)	4
Modulation of mitochondrial nucleoid structure during aging and by mtDNA content in Drosophila	4
Dirichlet process mixture models for single-cell RNA-seq clustering	4
Tight junction stabilization prevents HepaRG cell death in drug-induced intrahepatic cholestasis	4
Pressure-induced changes on the morphology and gene expression in mammalian cells	4
Ctdp1 deficiency leads to early embryonic lethality in mice and defects in cell cycle progression in MEFs	4
A new method to localise and quantify oxidative stress in live juvenile mussels	4
Drosophila hemocytes recognize lymph gland tumors of mxc mutants and activate the innate immune pathway in a reactive oxygen species-dependent manner	4
Investigating the effect of cholinergic and adrenergic blocking agents on maternal-fetal heart rates and their interactions in mice fetuses	4
A Year at the Forefront of Bacterial Defense Systems Against Neutrophilic Oxidants	4
Overexpression of Wnt7a enhances radiosensitivity of non-small-cell lung cancer via the Wnt/JNK pathway	4
The genomic basis of host and vector specificity in non-pathogenic trypanosomatids	4
RNA-seq analysis and compound screening highlight multiple signalling pathways regulating secondary cell death after acute CNS injuryin vivo	4
Patterns of variations in dorsal colouration of the Italian wall lizard Podarcis siculus	4
Integrated analysis of cell shape and movement in moving frame	4
Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor	4
Initial parasitic behaviour of the temporary social parasitic ant Polyrhachis lamellidens can be induced by host-like cuticles in laboratory environment	4
Chromatin dynamics through mouse preimplantation development revealed by single molecule localisation microscopy	4
Effects of short-term fasting on spontaneous activity and excess post-exercise oxygen consumption in four juvenile fish species with different foraging strategies	3
Twitchy, the Drosophila orthologue of the ciliary gating protein FBF1/dyf-19, is required for coordinated locomotion and male fertility	3
Odours of cancerous mouse congeners: detection and attractiveness	3
Home ranges, directionality and the influence of moon phases on the movement ecology of Indian flying fox males in southern India	3
Development of a cypovirus protein microcrystal-encapsulated Bacillus thuringiensis UV-tolerant and mosquitocidal δ-endotoxin	3
Germline competent mesoderm: the substrate for vertebrate germline and somatic stem cells?	3

Clutch may predict growth of hatchling Burmese pythons better than food availability or sex	3
MICAL-L1 is required for cargo protein delivery to the cell surface	3
Postnatal depletion of maternal cells biases T lymphocytes and natural killer cells’ profiles toward early activation in the spleen	3
Zebrafish embryos hatch early in response to chemical and mechanical indicators of predation risk, resulting in underdeveloped swimming ability of hatchling larvae	3
Exploiting the potential of lung stem cells to develop pro-regenerative therapies	3
HepT1-derived murine models of high-risk hepatoblastoma display vascular invasion, metastasis, and circulating tumor cells	3
Morpho-functional comparison of differentiation protocols to create iPSC-derived cardiomyocytes	3
The continuing challenge of paper-mills to publishing in the biological sciences	3
Valproic acid affects neurogenesis during early optic tectum development in zebrafish	3
LIM Homeobox 9 knockdown by morpholino does not affect zebrafish retinal development	3
Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle	3
GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network	3
Dorso-ventral heterogeneity in tracheal basal stem cells	3
Quantitative evaluation of individual food intake by insectivorous vespertilionid bats (Chiroptera, Vespertilionidae)	3
Drosophila CRISPR/Cas9 mutants as tools to analyse cardiac filamin function and pathogenicity of human FLNC variants	3
Kinetics of Arf1 inactivation regulates Golgi organisation and function in non-adherent fibroblasts	3
Novel protocol to observe the intestinal tuft cell using transmission electron microscopy	3
Coilin as a regulator of NF-kB mediated inflammation in preeclampsia	3
A machine vision system for tracking population behavior of zooplankton in small-scale experiments: a case study on salmon lice (Lepeophtheirus salmonis Krøyer, 1838) copepodite population resp	3
Crosstalk between basal extracellular matrix adhesion and building of apical architecture during morphogenesis	3
NEDD1-S411 phosphorylation plays a critical function in the coordination of microtubule nucleation during mitosis	3
The transcriptional landscape of the cultured murine middle ear epithelium in vitro	3
Vitamin A cycle byproducts explain retinal damage and molecular changes thought to initiate retinal degeneration	3
Comparative transcriptomics of tropical woody plants supports fast and furious strategy along the leaf economics spectrum in lianas	3
Unique histological features of the tail skin of cotton rat (Sigmodon hispidus) related to caudal autotomy	3
Multiple neural bHLHs ensure the precision of a neuronal specification event in Caenorhabditis elegans	3
DJ-1 promotes epithelial-to-mesenchymal transition via enhancing FGF9 expression in colorectal cancer	3
Correction: Characterization and analysis of CCR and CAD gene families at the whole-genome level for lignin synthesis of stone cells in pear (Pyrus bretschneideri) fruit	3
Genetically inducible and reversible zebrafish model of systemic inflammation	3
Parental exposure to ocean acidification impacts gamete production and physiology but not offspring performance in Nematostella vectensis	3
Construction of a human hTERT RPE-1 cell line with inducible Cre for editing of endogenous genes	3
Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage	3
Revisiting the flight dynamics of take-off of a butterfly: experiments and CFD simulations for a cabbage white butterfly	3
Focal sources of FGF-10 promote the buckling morphogenesis of the embryonic airway epithelium	3
Nondeterministic nature of sensorineural outcomes following noise trauma	3
Ac/Ds transposition for CRISPR/dCas9-SID4x epigenome modulation in zebrafish	3
Phosphosites of the yeast centrosome component Spc110 contribute to cell cycle progression and mitotic exit	3
A deep-dive into fictive locomotion – a strategy to probe cellular activity during speed transitions in fictively swimming zebrafish larvae	3
Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo	3
exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates	3
Evaluation of ellagic acid and gallic acid as efflux pump inhibitors in strains of Staphylococcus aureus	3
Maternal glucocorticoid levels during incubation predict breeding success, but not reproductive investment, in a free-ranging bird	3
Visualization of X chromosome reactivation in mouse primordial germ cells in vivo	3
Dynein-2–driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex	3
Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream	3
Spatial odor discrimination in the hawkmoth, Manduca sexta (L.)	3
Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryo	3