Biology Open

Article	Citations
First person – Daisy Pineda-Suazo	34
Primary human neutrophils and monocytes migrate along endothelial cell boundaries to optimize search efficiency under static in vitro conditions	33
Unpredictable aggressive defence of the venomous snake, Crotalus ravus, towards predators and humans	27
First person – Rajeshwari B. R.	26
Concrete consequences: construction on prime honey bee habitat doubles foraging distances	24
Local differences in robustness to ocean acidification	24
Cuticular microstructure of the locust femur–tibia joint	24
Hip stabilization in an australopithecine-like hip: the influence of shape on muscle activation	23
EyeHex toolbox for complete segmentation of ommatidia in fruit fly eyes	22
Reorganization of the heterochromatin-associated gene-dense subcompartment in early neuronal development	21
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut	19
Fast & Fair peer review: a bold experiment in scientific publishing	19
Divalent metal content in diet affects severity of manganese toxicity in Drosophila	18
A year at the forefront of plasmodesmal biology	18
Chromosomal organization of multigene families and meiotic analysis in species of Loricariidae (Siluriformes) from Brazilian Amazon, with description of a new cytotype for genus Spatuloricaria	17
Over-expressing NadA quinolinate synthase inEscherichia colienhances the bioelectrochemistry in microbial fuel cells	16
Macrophages allocate before apoptosis initiation and produce reactive oxygen species during interdigital phagocytosis	16
First person – Neha Jadhav Giridhar and Bita Hambrecht	15
Knee position affects medial gastrocnemius and soleus activation during dynamic plantarflexion: no evidence for an inter-muscle compensation in healthy young adults	15
Correction: Stable atrogin-1 (Fbxo32) and MuRF1 (Trim63) gene expression is involved in the protective mechanism in soleus muscle of hibernating Daurian ground squirrels (<	15
The importance of considering regulatory domains in genome-wide analyses – the nearest gene is often wrong!	14
Empowering tomorrow's leaders: the impact of the 15th Network of Young Researchers in Andrology (NYRA) meeting on male reproductive health and interdisciplinary collaboration	14
Young minds, deeper insights: a recap of the BMAS Summer School 2023, ranging from basic research to clinical implications of bone marrow adipose tissue	14
Shaping the future of male reproductive health: fostering talent at the 14th Network of Young Researchers in Andrology meeting	14
The Endosomal Sorting Complex, ESCRT, has diverse roles in blood progenitor maintenance, lineage choice and immune response	13

Retraction: Overexpression of long non-coding RNA SBF2-AS1 promotes cell progression in esophageal squamous cell carcinoma (ESCC) by repressing miR-494 to up-regulate PFN2 expression	13
Dynamic shapes of the zygote and two-cell mouse and human	12
shRNAs targeting mouseAdam10diminish cell response to proinflammatory stimuli independently ofAdam10silencing	12
Manipulating mitochondrial reactive oxygen species alters survival in unexpected ways in a Drosophila Cdk5 model of neurodegeneration	12
NANOS3 suppresses premature spermatogonial differentiation to expand progenitors and fine-tunes spermatogenesis in mice	12
First person – Franziska Hacker	12
An experimental test of chronic traffic noise exposure on parental behaviour and reproduction in zebra finches	11
EFEMP1 contributes to light-dependent ocular growth in zebrafish	10
Ccn2a acts downstream of cx43 to influence joint formation during zebrafish fin regeneration	10
Feeding a rich diet supplemented with the translation inhibitor cycloheximide decreases lifespan and ovary size in Drosophila	10
Fully automated point spread function analysis using PyCalibrate	10
Ethanol downregulates gastrula gene expression and cell movement, causing symptoms of foetal alcohol spectrum disorders	10
The relationship between locomotion and hindlimb morphology in the leopard (Panthera pardus) using a geometric morphometric approach	10
Fluorescent protein tags for human tropomyosin isoform comparison	10
Insulated piggyBac and FRT vectors for engineering transgenic homozygous and heterozygous eHAP cells	10
First person – Avery Hinks	10
From fossils to future – Jane Francis on polar exploration and changing climates	10
First person – Mikaela Scheer	10
First person – Avik Banerjee	10
First person – Tom Carruthers	10
Differential effect of ubiquitous and germline depletion of Integrator complex function on C. elegans physiology	10
Effects of blood extraction and ecophysiological experiments on stress in adult males of Liolaemus attenboroughi	9
The Abl-interactor Abi suppresses the function of the BRAG2 GEF family member Schizo	9
First person – Leah Eller	9
Social interactions among ants are impacted by food availability and group size	9
Winging it: hummingbirds alter flying kinematics during molt	9
First person – Angela Fan and Yoldas Yildiz	8
Bees display limited acclimation capacity for heat tolerance	8
Parental exposure to ocean acidification impacts gamete production and physiology but not offspring performance in Nematostella vectensis	8
SlicerMorph photogrammetry: an open-source photogrammetry workflow for reconstructing 3D models	8
Investigating the link between morphological characteristics and diet in an island population of omnivorous reptiles (Sphenodon punctatus)	8
Cellular senescence limits translational readthrough	8
Metabolic shift towards oxidative phosphorylation reduces cell-density-induced cancer-stem-cell-like characteristics in prostate cancer in vitro	8
Holding time has limited impact on constitutive innate immune function in a long-lived Antarctic seabird, the Adélie penguin: implications for field studies	8
Frequency-dependent avoidance movement of glass catfish in response to sinusoidal electrical stimulation and associated spiking patterns of electroreceptors	8
Normotensive metabolic syndrome in Transient Receptor Potential Canonical Channel type 1 Trpc1−/− mice.	8
Elucidating the genetic architecture of migratory timing in a songbird migrant, the great reed warbler, Acrocephalus arundinaceus	8
Glycogen synthase is required for heat shock-mediated autophagy induction in neuronal cells	8
First person – Isabelle Toussaint-Lardé	8
Hotter deserts and the impending challenges for the spiny-tailed Lizard in India	8
Response to Correspondence: Hajnal et al. ‘The role of lin-12 notch in C. elegans anchor cell proliferation’	7
ASCL2 is a key regulator of the proliferation–differentiation equilibrium in the esophageal epithelium	7
Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis	7
Aging disrupts spatiotemporal regulation of germline stem cells and niche integrity	7
CDX2 dose-dependently influences the gene regulatory network underlying human extraembryonic mesoderm development	7
Single-motor and multi-motor motility properties of kinesin-6 family members	7
Neural crest development and disorders: from patient to model system and back again – the NEUcrest conference	7
Mutational cooperativity of RUNX1::RUNX1T1 isoform 9a and oncogenic NRAS in zebrafish myeloid leukaemia	7
Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy	7
Protein complexes from mouse and chick brain that interact with phospho-KXGS motif tau/microtubule associated protein antibody	7

Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world	7
Reliable replicative lifespan determination of yeast with a single-channel microfluidic chip	7
Investigating the effect of cholinergic and adrenergic blocking agents on maternal-fetal heart rates and their interactions in mice fetuses	7
Meeting proceedings of the 43rd Indian Association for Cancer Research (IACR)	7
Retraction: Overexpression of Wnt7a enhances radiosensitivity of non-small-cell lung cancer via the Wnt/JNK pathway	7
Na,K-ATPase activity promotes macropinocytosis in colon cancer via Wnt signaling	7
The zebrafish ETS transcription factor Fli1b functions upstream of Scl/Tal1 during embryonic hematopoiesis	7
Retraction: MicroRNA-96-5p promotes proliferation, invasion and EMT of oral carcinoma cells by directly targeting FOXF2	7
Pacsin2 is required for endocytosis in the zebrafish pronephric tubule	7
Temporal integration and decision-making in crocodiles	6
Antimicrobial peptide expression in the cockroach gut during enterobacterial infection is specific and influenced by type III secretion	6
Vestigial-dependent induction contributes to robust patterning but is not essential for wing-fate recruitment in Drosophila	6
Characterization of alternative splicing during mammalian brain development reveals the extent of isoform diversity and potential effects on protein structural changes	6
Interaction between Discs large and Pins/LGN/GPSM2: a comparison across species	6
Partial role of volatile organic compounds in behavioural responses of mice to bedding from cancer-affected congeners	6
Insights into Octopus maya cathepsins from metatranscriptome and genome: structure evolutionary relationships and functional role prediction in digestive processes	6
Changes in mitochondrial distribution occur at the axon initial segment in association with neurodegeneration in Drosophila	6
First person – Latasha Ludwig	6
Coilin as a regulator of NF-kB mediated inflammation in preeclampsia	6
Morphlight theory inspired by raptors: musculoskeletal modeling and muscle control in Falco peregrinus wing flapping	6
Hormonal regulation of miRNA during mammary gland development	6
Increased expression of the small lysosomal gene SVIP in the Drosophila gut suppresses pathophysiological features associated with a high-fat diet	6
First person – Emily Bulger	6
Gait speed and incline modulate peak deceleration and timing of horizontal center of mass deceleration during double support	6
SOX2 and NR2F1 coordinate the gene expression program of the early postnatal visual thalamus	6
Arf6 is necessary for senseless expression in response to wingless signalling during Drosophila wing development	6
Computational anatomy and geometric shape analysis enables analysis of complex craniofacial phenotypes in zebrafish	6
Linking peak intensity of mechanically stimulated bioluminescence and cell surface area in dinoflagellates	6
Effects of vessel noise on beluga (Delphinapterus leucas) call type use: ultrasonic communication as an adaptation to noisy environments?	6
Metabolic scaling of fire ants ( Solenopsis invicta ) engaged in collective behaviors	6
Wnt and BMP signalling direct anterior–posterior differentiation in aggregates of mouse embryonic stem cells	6
An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes	6
A novel technique for atraumatic transurethral catheterisation of male rats	6
Alpha-T-catenin is expressed in peripheral nerves as a constituent of Schwann cell adherens junctions	5
Innervation of the developing kidney in vivo and in vitro	5
Biomechanical analysis of little penguins’ underwater locomotion from the free-ranging dive data	5
Maintenance of neuronal fate and transcriptional identity	5
Alterations in lifespan and sleep:wake duration under selective monochromes of visible light in Drosophila melanogaster	5
Experimental short-term heatwaves negatively impact body weight gain and survival during larval development in Bombus terrestris L. (Hymenoptera: Apidae)	5
Sox8: a multifaceted transcription factor in development and disease	5
exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates	5
Reevaluating the relationship between EGL-43 (EVI1) and LIN-12 (Notch) during C. elegans anchor cell invasion	5
First person – Kelly Diamond	5
Ethanol induces subcellular trafficking of the RNA-binding protein, hnRNP A1, in neuronal cells in vitro, but not in the peripubertal rat brain	5
Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect	5
Experimental playback of urban noise does not affect cognitive performance in captive Australian magpies	5
Deletion of taf1 and taf5 in zebrafish capitulate cardiac and craniofacial abnormalities associated with TAFopathies through perturbations in metabolism	5
Gene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish (Fundulus heteroclitus)	5
Cdc48 and its co-factor Ufd1 extract CENP-A from centromeric chromatin and can induce chromosome elimination in the fission yeast Schizosaccharomyces pombe	5
Regulation of NANOG and SOX2 expression by activin A and a canonical WNT agonist in bovine embryonic stem cells and blastocysts	5
Zebrafish embryos hatch early in response to chemical and mechanical indicators of predation risk, resulting in underdeveloped swimming ability of hatchling larvae	5
Stress-induced elemental retention in an ectothermic vertebrate	5
Plpp3, a novel regulator of pluripotency exit and endodermal differentiation of mouse embryonic stem cells	5
Saccharomyces cerevisiae deficient in the early anaphase release of Cdc14 can traverse anaphase I without ribosomal DNA disjunction and successfully complete meiosis	5
First person – Adam Downie	5
Actin cytoskeleton in angiogenesis	5
Intermittent hypoxia differentially affects metabolic and oxidative stress responses in two species of cyprinid fish	5
microRNA-guided immunity against respiratory virus infection in human and mouse lung cells	5
A Drosophila model of mitochondrial disease phenotypic heterogeneity	5
First person – Francesca Mastropasqua and Marika Oksanen	5
Vitamin A cycle byproducts explain retinal damage and molecular changes thought to initiate retinal degeneration	5
PatternJ: an ImageJ toolset for the automated and quantitative analysis of regular spatial patterns found in sarcomeres, axons, somites, and more	5
First person – Amy Irving	5
Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo	5
First person – Ming-Hsuan Wen	4
Introducing Daniel Gorelick – a new Editor-in-Chief for Biology Open	4
Population-level antagonism between FGF and BMP signaling steers mesoderm differentiation in embryonic stem cells	4
Correction: IRS-1 increases TAZ expression and promotes osteogenic differentiation in rat bone marrow mesenchymal stem cells	4
Low colostrum intake results in potential accumulation of peroxisome lipid substrates in vaginal tissue of 3-week-old gilts	4
trithorax is an essential regulator of cardiac Hox gene expression and anterior-posterior patterning of the Drosophila embryonic heart tube	4
Characterization of nitric oxide in Octopus maya nervous system and its potential role in sensory perception	4
Metabolic FRET sensors in intact organs: Applying spectral unmixing to acquire reliable signals	4
First person – Matthew Penaso-Stinson and Summer Paulson	4
Hepatic leukemia factor-expressing paraxial mesoderm cells contribute to the developing brain vasculature	4
First person – Neydiana Pina-Lopes	4
So long, and thanks for all the papers about fish (and other organisms too)	4
IFT139 regulates Hedgehog signaling and cilia structure through ciliary protein localization	4
Development of a cypovirus protein microcrystal-encapsulated Bacillus thuringiensis UV-tolerant and mosquitocidal δ-endotoxin	4
Dirichlet process mixture models for single-cell RNA-seq clustering	4
First person – Daniel Lenthall	4

Correction: Polyphyllin II inhibits liver cancer cell proliferation, migration and invasion through downregulated cofilin activity and the AKT/NF-κB pathway	4
Beyond bold versus shy: Zebrafish exploratory behavior falls into several behavioral clusters and is influenced by strain and sex	4
PTP10D-mediated cell competition is not obligately required for elimination of polarity-deficient clones	4
Future leader to watch – Nathan Harmston	4
Expression levels and activities of energy-yielding ATPases in the oligohaline neritid snail Theodoxus fluviatilis under changing environmental salinities	4
The next stage in Biology Open's support for early-career researchers	4
Elliptical Fourier analysis of hominoid radius shape: implications for Ardipithecus ramidus	4
First person – Ricardo Villalba-Briones	4
Development of the dictyostelid Polysphondylium violaceum does not require secreted cAMP	4
BBQ methods: streamlined workflows for bacterial burden quantification in infected cells by confocal microscopy	4
Altered epithelial development of the lateral ventricle choroid plexus in Mllt11 mutants	4
A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe syndrome	4
Tbx5 overexpression in embryoid bodies increases TAK1 expression but does not enhance the differentiation of sinoatrial node cardiomyocytes	4
The lymphatic system favours survival of a unique T. brucei population	4
Identification of a new allele of O-fucosyltransferase 1 involved in Drosophila intestinal stem cell regulation	4
A larval zebrafish model of cardiac physiological recovery following cardiac arrest and myocardial hypoxic damage	4
First person – Yixing Wu and Ying Bai	4
First person – Fatima Batool	4
First person – Valentina Laverde	4
Flavonols do not affect aphid load in green or senescing birch leaves but coincide with a decrease in Photosystem II functionality	4
First person – Alexandra Venuto	4
Theoretical model of impact mitigation mechanisms inherent to the North American bison skull	4
EphA1 receptor tyrosine kinase is localized to the nucleus in rhabdomyosarcoma from multiple species	4
midline represses Dpp signaling and target gene expression in Drosophila ventral leg development	4
Spatial structure could explain the maintenance of alternative reproductive tactics in tree cricket males	4
Analysis of the chromatin landscape and RNA polymerase II binding at SIN3-regulated genes	3
Lifespan and ROS levels in different Drosophila melanogaster strains after 24 h hypoxia exposure	3
Human in vivo medial gastrocnemius gear during active and passive muscle lengthening: effect of inconsistent methods and nomenclature on data interpretation	3
Discontinuous, biphasic, ontogenetic shifts in the metabolic allometry of aquatic animals?	3
Context-dependent thermolability of sex determination in a lacertid lizard with heteromorphic sex chromosomes	3
PIWIL2 downregulation in colon cancer promotes transposon activity and pro-tumorigenic phenotypes	3
A Year at the Forefront of Hydrostat Motion	3
A genome-wide CRISPR screen implicates plasma membrane asymmetry in exogenous C6-ceramide toxicity	3
Neurotranscriptomic profiling of Deformed Wing Virus-infected honey bee foragers ( Apis mellifera ) with different cognitive abilities	3
Automated counting of Drosophila imaginal disc cell nuclei	3
Biology Open 2023 – a year in review	3
Computational tools for quantifying actin filament numbers, lengths, and bundling	3
2024 Argentine Group for Extracellular Vesicles (GAVE) Workshop: promoting science in challenging times	3
In vitro forestomach digestion experiments give less-biased estimates of food composition in odontocetes	3
Characterization of gene cluster heterogeneity in single-cell transcriptomic data within and across cancer types	3
Muscle forces and the demands of turning while walking	3
Identification of a postnatal period of interdependent neurogenesis and apoptosis in peripheral neurons	3
First person – Sarit Pal	3
Connexin 43 mediated collective cell migration is independent of Golgi orientation	3
First person – Santu Saha	3
Allorecognition behaviors in Myxomycetes respond to intraspecies factors	3
Minimal functional domains of the core polarity regulator Dlg	3
Instantaneous visual genotyping and facile site-specific transgenesis via CRISPR-Cas9 and phiC31 integrase	3
Kinetics of Arf1 inactivation regulates Golgi organisation and function in non-adherent fibroblasts	3
Hansenula polymorpha cells lacking the ER-localized peroxins Pex23 or Pex29 show defects in mitochondrial function and morphology	3
A pro-angiogenic and hypoxic zebrafish model as a novel platform for anti-angiogenic drug testing	3
The factory, the antenna and the scaffold: the three-way interplay between the Golgi, cilium and extracellular matrix underlying tissue function	3
Constructing a doxycycline-inducible system for an epithelial-to-mesenchymal transition model in MCF10A cells	3
Effects of mechanical stimulation on metabolomic profiles of SW1353 chondrocytes: shear and compression	3
Hands-on training in structural biology, a tool for sustainable development in Africa series 4	3
Ecology, ethology, and evolution in the Anthropocene	3
foxg1a is required for hair cell development and regeneration in the zebrafish lateral line	3
Neurophysiological measurements of planarian brain activity: a unique model for neuroscience research	3
Alveolar epithelial paxillin in postnatal lung alveolar development	3
Developmental disorders caused by haploinsufficiency of transcriptional regulators: a perspective based on cell fate determination	3
First person – Bailey Calder	3
CD133/Prom1 marks proximal mouse oviduct epithelial progenitors and adult epithelial cells with a low generative capacity	3
Early-life challenge enhances cortisol regulation in zebrafish larvae	3
First person – Andreas Enström	3
First person – Martha S. C. Xelhuantzi	3
First person – Meg Watt	3
Differential effects of Mendelian GDAP1 clinical variants on mitochondria-lysosome membrane contacts sites	3
Re-assessment of the subcellular localization of Bazooka/Par-3 in Drosophila: no evidence for localization to the nucleus and the neuromuscular junction	3
Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia	3
Zebrafish models of alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye	3
First person – Mai Nguyen	3
Generation of mice with combined Hexa Gly269Ser KI or KO and Neu3 KO alleles to create new models of GM2 gangliosidoses	3
The uncoating of EV71 in mature late endosomes requires CD-M6PR	3
A simple, fast and inexpensive approach using E. coli to detect and estimate vitamin B12 content in microbial extracts	3
Temporal transcriptomic profiling of human three-dimensional neuromuscular co-cultures	3
Flat mount preparation for whole-mount fluorescent imaging of zebrafish embryos	3
insideOutside: an accessible algorithm for classifying interior and exterior points, with applications in embryology	3
Ecophysiology of neotropical amphibians and reptiles: lessons learned from Colombia	3
New horizons of microphysiological systems: India forging its path in human-relevant research	3
Establishment of a novel protocol for formalin-fixed paraffin-embedded organoids and spheroids	3
Inherited anoxia tolerance and growth performance can result in enhanced invasiveness in hybrid fish	3
Mass loss, timing and duration of catastrophic moult in little penguins	3
Ammonia transport mediated by urea transporter A isoforms	3
Bioengineering of a tumour-stroma 3D-tumouroid co-culture model of hypopharyngeal cancer	3
A high-resolution bovine mitochondrial co-expression network	3
Imp and Chinmo are required for embryonic motor neuron axon and dendrite targeting	3
First person – Sophie Kraunsoe	3
Meeting Review of the ‘1st Azerbaijan Neuroscience School: Introduction’	3
Reflections on the EMBO Workshop: Neuroscience of Sleep 2025	3