Biology Open

Article	Citations
Cardiac myosin super relaxation (SRX): a perspective on fundamental biology, human disease and therapeutics	55
Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease	42
Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice	33
BMP-treated human embryonic stem cells transcriptionally resemble amnion cells in the monkey embryo	32
Quantified growth of the human embryonic heart	30
Efficient and crucial quality control of HAP1 cell ploidy status	28
Uncharted routes: exploring the relevance of auxin movement via plasmodesmata	25
A versatile, automated and high-throughput drug screening platform for zebrafish embryos	23
RNA-Seq reveals changes in human placental metabolism, transport and endocrinology across the first–second trimester transition	23
Three-dimensional model of glioblastoma by co-culturing tumor stem cells with human brain organoids	20
Beyond bold versus shy: Zebrafish exploratory behavior falls into several behavioral clusters and is influenced by strain and sex	20
Genome wide association study for the identification of genes associated with tail fat deposition in Chinese sheep breeds	18
Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research	18
Local adaptation in thermal tolerance for a tropical butterfly across ecotone and rainforest habitats	18
Redundant functions of the SLC5A transporters Rumpel, Bumpel, and Kumpel in ensheathing glial cells	17
The LRRK2 signaling network converges on a centriolar phospho-Rab10/RILPL1 complex to cause deficits in centrosome cohesion and cell polarization	17
Developmental disorders caused by haploinsufficiency of transcriptional regulators: a perspective based on cell fate determination	16
Basement membrane dynamics and mechanics in tissue morphogenesis	15
CD47 differentially regulates white and brown fat function	15
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane	15
Bisphenol A promotes stress granule assembly and modulates the integrated stress response	14
Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world	14
Auxin confers protection against ER stress in Caenorhabditis elegans	14
Conditional targeting of phosphatidylserine decarboxylase to lipid droplets	14
Motion: enhancing signals and concealing cues	14

20-hydroxyecdysone (20E) signaling regulates amnioserosa morphogenesis during Drosophila dorsal closure: EcR modulates gene expression in a complex with the AP-1 subunit, Jun	13
A Caenorhabditis elegans behavioral assay distinguishes early stage prostate cancer patient urine from controls	13
The SARS-CoV-2 receptor and other key components of the Renin-Angiotensin-Aldosterone System related to COVID-19 are expressed in enterocytes in larval zebrafish	13
Stability of amino acids and related amines in human serum under different preprocessing and pre-storage conditions based on iTRAQ®-LC-MS/MS	13
Altered germline cyst formation and oogenesis in Tex14 mutant mice	13
Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis	12
Actin cytoskeleton in angiogenesis	12
Presynaptic HCN channels constrain GABAergic synaptic transmission in pyramidal cells of the medial prefrontal cortex	12
Influence of weighted downhill running training on serial sarcomere number and work loop performance in the rat soleus	12
Auxin treatment increases lifespan in Caenorhabditis elegans	11
Eye morphogenesis in the blind Mexican cavefish	11
KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance	11
Efficient induction and sustenance of pluripotent stem cells from bovine somatic cells	11
Computational anatomy and geometric shape analysis enables analysis of complex craniofacial phenotypes in zebrafish	11
Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect	10
RGS5: a novel role as a hypoxia-responsive protein that suppresses chemokinetic and chemotactic migration in brain pericytes	10
Quantitative analysis of signaling responses during mouse primordial germ cell specification	10
Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs	10
Convergent acoustic community structure in South Asian dry and wet grassland birds	10
Soluble receptor for advanced glycation end products protects from ischemia- and reperfusion-induced acute kidney injury	10
Muscle forces and the demands of human walking	10
Design of a 3D printed, motorized, uniaxial cell stretcher for microscopic and biochemical analysis of mechanotransduction	9
Biophysical and biochemical properties of Deup1 self-assemblies: a potential driver for deuterosome formation during multiciliogenesis	9
Evaluation of ellagic acid and gallic acid as efflux pump inhibitors in strains of Staphylococcus aureus	9
High glucose induces Nox4 expression and podocyte apoptosis through the Smad3/ezrin/PKA pathway	9
Variations in oxidative stress and antioxidant defense level during different phases of hibernation in common Asian toad,Duttaphrynus melanostictus	9
Effect of heterogeneous substrate adhesivity of follower cells on speed and tension profile of leader cells in primary keratocyte collective cell migration	9
Pigment pattern morphospace ofDaniofishes: evolutionary diversification and mutational effects	9
Connecting different heart diseases through intercellular communication	9
Lifespan and ROS levels in different Drosophila melanogaster strains after 24 h hypoxia exposure	8
Establishment of a novel protocol for formalin-fixed paraffin-embedded organoids and spheroids	8
Phenotype assessment for neurodegenerative murine models with ataxia and application to Niemann–Pick disease, type C1	8
The importance of considering regulatory domains in genome-wide analyses – the nearest gene is often wrong!	8
Apoptosis is a generator of Wnt-dependent regeneration and homeostatic cell renewal in the ascidian Ciona	8
Requirement for STAT3 and its target, TFCP2L1, in self-renewal of naïve pluripotent stem cells in vivo and in vitro	8
Tissue-specific transcriptome profiles identify functional differences key to understanding whole plant response to life in variable salinity	8
The uncoating of EV71 in mature late endosomes requires CD-M6PR	8
Modulation of retinoid-X-receptors differentially regulates expression of apolipoprotein genes apoc1 and apoeb by zebrafish microglia	8
Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing	8
Validating accelerometry-derived proxies of energy expenditure using the doubly labelled water method in the smallest penguin species	8
The Drosophila orthologue of the primary ciliary dyskinesia-associated gene, DNAAF3, is required for axonemal dynein assembly	8
Smoking flies: testing the effect of tobacco cigarettes on heart function ofDrosophila melanogaster	8
A glucose-supplemented diet enhances gut barrier integrity in Drosophila	8
Zebrafish embryos hatch early in response to chemical and mechanical indicators of predation risk, resulting in underdeveloped swimming ability of hatchling larvae	8
Orally administered branaplam does not impact neurogenesis in juvenile mice, rats, and dogs	7
Transduction of rat and human adipose-tissue derived mesenchymal stromal cells by adeno-associated viral vector serotype DJ	7
Associative learning in larval and adultDrosophilais impaired by the dopamine-synthesis inhibitor 3-Iodo-L-tyrosine	7
A nematode-derived, mitochondrial stress signaling-regulated peptide exhibits broad antibacterial activity	7
The dorsal blastopore lip is a source of signals inducing planar cell polarity in the Xenopus neural plate	7
Src family kinases inhibit differentiation of intestinal epithelial cells through the Hippo effector YAP1	7

Heart rate and startle responses in diving, captive harbour porpoises (Phocoena phocoena) exposed to transient noise and sonar	7
Fracture biomechanics influence local and systemic immune responses in a murine fracture-related infection model	7
Serotonin: an overlooked regulator of endocytosis and endosomal sorting?	7
Regulation of NANOG and SOX2 expression by activin A and a canonical WNT agonist in bovine embryonic stem cells and blastocysts	7
Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic transport, γH2AX accumulation, and Bax/Bak-dependence	7
Perinatal exposure to synergistic multiple stressors leads to cellular and behavioral deficits mimicking Schizophrenia-like pathology	7
DNMT1 is a negative regulator of osteogenesis	7
Tight junction stabilization prevents HepaRG cell death in drug-induced intrahepatic cholestasis	7
MicroRNA-9-5p inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting peroxisome proliferator-activated receptor β	7
Alone in a crowd: effect of a nonfunctional lateral line on expression of the social hormone parathyroid hormone 2	6
Antimicrobial peptide expression in the cockroach gut during enterobacterial infection is specific and influenced by type III secretion	6
MonitoringSchizosaccharomyces pombegenome stress by visualizing end-binding protein Ku	6
Viral species differentially influence macronutrient preferences based on honey bee genotype	6
Developmental expression patterns of toolkit genes in male accessory gland ofDrosophilaparallels those of mammalian prostate	6
Deep learning enabled multi-organ segmentation of mouse embryos	6
Multiple neural bHLHs ensure the precision of a neuronal specification event in Caenorhabditis elegans	6
Zebrafish models of alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye	6
A Year at the Forefront of Engineering Photosynthesis	6
GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network	6
Postnatal expression profiles of atypical cadherin FAT1 suggest its role in autism	6
Exocrine pancreas proteases regulate β-cell proliferation in zebrafish ciliopathy models and in murine systems	6
Patterns of variations in dorsal colouration of the Italian wall lizard Podarcis siculus	6
Oviductal fluid counterbalances the negative effect of high temperature on sperm in an ectotherm model	6
Pressure-induced changes on the morphology and gene expression in mammalian cells	6
Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia	6
A kinase translocation reporter reveals real-time dynamics of ERK activity in Drosophila	6
A mouse model displays host and bacterial strain differences in Aerococcus urinae urinary tract infection	6
A guide to preprinting for early-career researchers	6
Mutations in the splicing regulator Prp31 lead to retinal degeneration in Drosophila	6
Using CRISPR/Cas9 to identify genes required for mechanosensory neuron development and function	6
Energetics of whiskered bats in comparison to other bats of the family Vespertilionidae	6
Mummichog gill and operculum exhibit functionally consistent claudin-10 paralog profiles and Claudin-10c hypersaline response	6
A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe syndrome	6
Visualization of X chromosome reactivation in mouse primordial germ cells in vivo	6
Interaction between Discs large and Pins/LGN/GPSM2: a comparison across species	6
The continuing challenge of paper-mills to publishing in the biological sciences	5
Comparative transcriptomics of tropical woody plants supports fast and furious strategy along the leaf economics spectrum in lianas	5
Revisiting the flight dynamics of take-off of a butterfly: experiments and CFD simulations for a cabbage white butterfly	5
Effects of particle size and thickness of quartz sand on the webbed foot kinematics of mallard (Anas platyrhynchos)	5
Single-cell sequencing reveals the potential oncogenic expression atlas of human iPSC-derived cardiomyocytes	5
The thermal dependence and molecular basis of physiological color change in Takydromus septentrionalis (Lacertidae)	5
Vitamin D receptor absence does not enhance intestinal tumorigenesis in ApcPirc/+rats	5
Dirichlet process mixture models for single-cell RNA-seq clustering	5
Three functional polymorphisms in CCDC170 were associated with osteoporosis phenotype	5
Development of a highly pulmonary metastatic orthotopic renal cell carcinoma murine model	5
Metabolic scaling of fire ants (Solenopsis invicta) engaged in collective behaviors	5
Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryo	5
Drosophila hemocytes recognize lymph gland tumors of mxc mutants and activate the innate immune pathway in a reactive oxygen species-dependent manner	5
Investigating the effect of cholinergic and adrenergic blocking agents on maternal-fetal heart rates and their interactions in mice fetuses	5
Modulation of mitochondrial nucleoid structure during aging and by mtDNA content in Drosophila	5
EPCAM and TROP2 share a role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice	5
Focal sources of FGF-10 promote the buckling morphogenesis of the embryonic airway epithelium	5
Dynein-2–driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex	5
Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor	5
Factors affecting gestation periods in elasmobranch fishes	5
Construction of a human hTERT RPE-1 cell line with inducible Cre for editing of endogenous genes	5
Influence of maternal diet on offspring survivorship, growth, and reproduction in a sheetweb spider	5
Dorso-ventral heterogeneity in tracheal basal stem cells	5
Research culture: science from bench to society	5
BBQ methods: streamlined workflows for bacterial burden quantification in infected cells by confocal microscopy	5
Rhoptry kinase protein 39 (ROP39) is a novel factor that recruits host mitochondria to the parasitophorous vacuole of Toxoplasma gondii	5
Ctdp1 deficiency leads to early embryonic lethality in mice and defects in cell cycle progression in MEFs	4
Unique histological features of the tail skin of cotton rat (Sigmodon hispidus) related to caudal autotomy	4
Chromatin dynamics through mouse preimplantation development revealed by single molecule localisation microscopy	4
A new method to localise and quantify oxidative stress in live juvenile mussels	4
Phosphosites of the yeast centrosome component Spc110 contribute to cell cycle progression and mitotic exit	4
A Year at the Forefront of Bacterial Defense Systems Against Neutrophilic Oxidants	4
Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream	4
An experimental test of chronic traffic noise exposure on parental behaviour and reproduction in zebra finches	4
Development of a cypovirus protein microcrystal-encapsulated Bacillus thuringiensis UV-tolerant and mosquitocidal δ-endotoxin	4
Postnatal depletion of maternal cells biases T lymphocytes and natural killer cells’ profiles toward early activation in the spleen	4
Exploiting the potential of lung stem cells to develop pro-regenerative therapies	4
Interdomain interactions regulate the localization of a lipid transfer protein at ER-PM contact sites	4
Morpho-functional comparison of differentiation protocols to create iPSC-derived cardiomyocytes	4
What drives mixed-species shoaling among wild zebrafish? The roles of predators, food access, abundance of conspecifics and familiarity	4
Coilin as a regulator of NF-kB mediated inflammation in preeclampsia	4
A Year at the Forefront of Proteostasis and Aging	4
Light-sheet microscopy reveals dorsoventral asymmetric membrane dynamics ofAmoeba proteusduring pressure-driven locomotion	4
Modelling the structure of Short Gastrulation and generation of a toolkit for studying its function in Drosophila	4
Genetically inducible and reversible zebrafish model of systemic inflammation	4

Deficiency of the Heterogeneous Nuclear Ribonucleoprotein U locus leads to delayed hindbrain neurogenesis	4
The genomic basis of host and vector specificity in non-pathogenic trypanosomatids	4
Vitamin A cycle byproducts explain retinal damage and molecular changes thought to initiate retinal degeneration	4
Valproic acid affects neurogenesis during early optic tectum development in zebrafish	4
Integrated analysis of cell shape and movement in moving frame	4
Initial parasitic behaviour of the temporary social parasitic ant Polyrhachis lamellidens can be induced by host-like cuticles in laboratory environment	4
Kinetics of Arf1 inactivation regulates Golgi organisation and function in non-adherent fibroblasts	4
Quantitative evaluation of individual food intake by insectivorous vespertilionid bats (Chiroptera, Vespertilionidae)	4
Insights into in vivo adipocyte differentiation through cell-specific labeling in zebrafish	4
Mapping the transcriptomic changes of endothelial compartment in human hippocampus across aging and mild cognitive impairment	4
MiR-145-5p overexpression rejuvenates aged adipose stem cells and accelerates wound healing	4
Odours of cancerous mouse congeners: detection and attractiveness	4
Ac/Ds transposition for CRISPR/dCas9-SID4x epigenome modulation in zebrafish	4
A deep-dive into fictive locomotion – a strategy to probe cellular activity during speed transitions in fictively swimming zebrafish larvae	4
Dissecting dynamics and differences of selective pressures in the evolution of human pigmentation	4
Effects of mechanical stimulation on metabolomic profiles of SW1353 chondrocytes: shear and compression	4
Promyelocytic leukemia nuclear body-like structures can assemble in mouse oocytes	3
Neural stem cell research in Africa: current realities and future prospects	3
Minimal functional domains of the core polarity regulator Dlg	3
Clutch may predict growth of hatchling Burmese pythons better than food availability or sex	3
Differential effects of Mendelian GDAP1 clinical variants on mitochondria-lysosome membrane contacts sites	3
Home ranges, directionality and the influence of moon phases on the movement ecology of Indian flying fox males in southern India	3
Nondeterministic nature of sensorineural outcomes following noise trauma	3
Single-motor and multi-motor motility properties of kinesin-6 family members	3
MICAL-L1 is required for cargo protein delivery to the cell surface	3
LIM Homeobox 9 knockdown by morpholino does not affect zebrafish retinal development	3
exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates	3
Visual acuity of budgerigars for moving targets	3
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut	3
Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle	3
Population-level antagonism between FGF and BMP signaling steers mesoderm differentiation in embryonic stem cells	3
Melanistic coloration does not influence thermoregulation in the crepuscular gecko Eublepharis macularius	3
HepT1-derived murine models of high-risk hepatoblastoma display vascular invasion, metastasis, and circulating tumor cells	3
Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage	3
CD133/Prom1 marks proximal mouse oviduct epithelial progenitors and adult epithelial cells with a low generative capacity	3
Germline competent mesoderm: the substrate for vertebrate germline and somatic stem cells?	3
Automated counting of Drosophila imaginal disc cell nuclei	3
Crosstalk between basal extracellular matrix adhesion and building of apical architecture during morphogenesis	3
Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development	3
Bees display limited acclimation capacity for heat tolerance	3
Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo	3
Parental exposure to ocean acidification impacts gamete production and physiology but not offspring performance in Nematostella vectensis	3
Inter- and intra-limb coordination during initial sprint acceleration	3
A monoclonal antibody raised against human EZH2 cross-reacts with the RNA-binding protein SAFB	3
The influence of claw morphology on gripping efficiency	3
Novel protocol to observe the intestinal tuft cell using transmission electron microscopy	3
Elevated temperatures increase abnormalities in embryos and reduce larval survival in serpulid polychaetes	3
Drosophila CRISPR/Cas9 mutants as tools to analyse cardiac filamin function and pathogenicity of human FLNC variants	3
RhoGAP RGA-8 supports morphogenesis in C. elegans by polarizing epithelia	3
Loss of Elp1 perturbs histone H2A.Z and the Notch signaling pathway	3
Twitchy, the Drosophila orthologue of the ciliary gating protein FBF1/dyf-19, is required for coordinated locomotion and male fertility	3
Introducing blood flow in kidney explants by engraftment onto the chick chorioallantoic membrane is not sufficient to induce arterial smooth muscle cell development	3
Isolation and evaluation of erythroid progenitors in the livers of larval, froglet, and adult Xenopus tropicalis	3
NEDD1-S411 phosphorylation plays a critical function in the coordination of microtubule nucleation during mitosis	3
Spatial odor discrimination in the hawkmoth, Manduca sexta (L.)	3
The transcriptional landscape of the cultured murine middle ear epithelium in vitro	3
The prospect of genetically engineering natural killer cells for cancer immunotherapy	3
Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy	2
Defective COX1 expression in aging mice liver	2
Plpp3, a novel regulator of pluripotency exit and endodermal differentiation of mouse embryonic stem cells	2
Aging disrupts spatiotemporal regulation of germline stem cells and niche integrity	2
Standing horse posture: a longer stance is more stable	2
PTP10D-mediated cell competition is not obligately required for elimination of polarity-deficient clones	2
Development of the dictyostelid Polysphondylium violaceum does not require secreted cAMP	2
Towards an objective measurement of sleep quality in non-human animals: using the horse as a model species for the creation of sleep quality indices	2
Empowering tomorrow's leaders: the impact of the 15th Network of Young Researchers in Andrology (NYRA) meeting on male reproductive health and interdisciplinary collaboration	2
Dynamic shapes of the zygote and two-cell mouse and human	2
The lymphatic system favours survival of a unique T. brucei population	2
Identification of a new allele of O-fucosyltransferase 1 involved in Drosophila intestinal stem cell regulation	2
Expression levels and activities of energy-yielding ATPases in the oligohaline neritid snail Theodoxus fluviatilis under changing environmental salinities	2
Avoiding being stung or bitten – prey capture behaviors of the ant-eating Texas horned lizard (Phrynosoma cornutum)	2
A zebrafish forward genetic screen identifies an indispensable threonine residue in the kinase domain of PRKD2	2
Alpha-T-catenin is expressed in peripheral nerves as a constituent of Schwann cell adherens junctions	2
Flavonols do not affect aphid load in green or senescing birch leaves but coincide with a decrease in Photosystem II functionality	2
Low colostrum intake results in potential accumulation of peroxisome lipid substrates in vaginal tissue of 3-week-old gilts	2
Cellular senescence limits translational readthrough	2
Aneuploidy facilitates dysplastic and tumorigenic phenotypes in the Drosophila gut	2
A universal method for generating knockout mice in multiple genetic backgrounds using zygote electroporation	2
CRISPR/Cas9-mediated knockout of the ubiquitin variant UbKEKS reveals a role in regulating nucleolar structures and composition	2
Young minds, deeper insights: a recap of the BMAS Summer School 2023, ranging from basic research to clinical implications of bone marrow adipose tissue	2
Heart rate as a proxy for estimating oxygen consumption rates in loggerhead turtles (Caretta caretta)	2
The population frequency of human mitochondrial DNA variants is highly dependent upon mutational bias	2
Human in vivo medial gastrocnemius gear during active and passive muscle lengthening: effect of inconsistent methods and nomenclature on data interpretation	2
Over-expressing NadA quinolinate synthase inEscherichia colienhances the bioelectrochemistry in microbial fuel cells	2
Targeted mass spectrometry for monitoring of neural differentiation	2
Early-career researchers: answering the most important scientific questions of our time	2
Morphological mechanism allowing a parasitic leech, Ozobranchus jantseanus (Rhynchobdellida: Ozobranchidae), to survive in ultra-low temperatures	2
Metabolic shift towards oxidative phosphorylation reduces cell-density-induced cancer-stem-cell-like characteristics in prostate cancer in vitro	2
Quantifying acute kidney injury in an Ischaemia-Reperfusion Injury mouse model using deep-learning-based semantic segmentation in histology	2
Investigating the link between morphological characteristics and diet in an island population of omnivorous reptiles (Sphenodon punctatus)	2
Shaping the future of male reproductive health: fostering talent at the 14th Network of Young Researchers in Andrology meeting	2
NANOS3 suppresses premature spermatogonial differentiation to expand progenitors and fine-tunes spermatogenesis in mice	2
Clonal behaviour of myogenic precursor cells throughout the vertebrate lifespan	2
High-throughput detection of eukaryotic parasites and arboviruses in mosquitoes	2
Chk2-p53 and JNK in irradiation-induced cell death of hematopoietic progenitors and differentiated cells inDrosophilalarval lymph gland	2