OOIR: Observatory of International Research

Papers

(The TQCC of Bone & Joint Research is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	113
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	74
Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density	69
Candy box technique with sutures and Nice knot	69
Prognostic factors associated with failure of total elbow arthroplasty	59
Mental health implications of fracture-related infections	58
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	52
Comparison of periprosthetic femoral fracture torque and strain pattern of three types of femoral components in experimental model	41
Intra-articular celecoxib improves knee extension regardless of surgical release in a rabbit model of arthrofibrosis	41
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	40
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	38
Can severity of trunnion damage be estimated by visual inspection alone?	38
The metabolic equivalent of task score	35
Effect of the additional anteroposterior blocking screw on nail/medullary canal mismatch after cephalomedullary nailing in unstable pertrochanteric fracture	34
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	32
Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	32
Diagnosing periprosthetic joint infections	29
Application of loaded graphene oxide biomaterials in the repair and treatment of bone defects	28
Discogenic pain in lumbar vertebra	28
Preoperative measures of bone mineral density from digital wrist radiographs	27
Osteochondral lesions of talus	27
Finite element analysis safety of tibial cortex transverse transport	27
Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway	24
Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis	24
Prediction of implant failure risk due to periprosthetic femoral fracture after primary elective total hip arthroplasty	24

Therapeutic potential of IκB kinase epsilon inhibition in preventing meniscal degeneration of early osteoarthritis	24
Hederagenin promotes SIRT6 to attenuate epidural scar formation by aggravating PRMT1 deacetylation	22
The CREB1 inhibitor 666-15 maintains cartilage homeostasis and mitigates osteoarthritis progression	22
Beyond the surface: anterior cruciate ligament assessment in knee osteoarthritis	22
The role of cells and signal pathways in subchondral bone in osteoarthritis	22
Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27^kip1 pathway	21
Transcriptome-wide association study identifies new susceptibility genes for degenerative cervical spondylosis	21
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats	20
Detection limitations of bacteria in tissue samples	20
Histone deacetylase inhibitors attenuated interleukin-1β-induced chondrogenesis inhibition in synovium-derived mesenchymal stem cells of the temporomandibular joint	19
High-intensity running exercise promotes knee meniscal damage via the PI3K/AKT/mTOR axis	19
CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro	19
A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis	19
Detection of rare microorganisms in bone and joint infections by metagenomic next-generation sequencing	19
Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing	18
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice	18
Future registry research	18
Tibial cortex transverse transport accelerates wound healing via enhanced angiogenesis and immunomodulation	18
Human acellular amniotic membrane scaffolds encapsulating juvenile cartilage fragments accelerate the repair of rabbit osteochondral defects	17
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages	16
Identification of age-related genes in rotator cuff tendon	16
A large-scale genetic correlation scan between rheumatoid arthritis and human plasma protein	16
Current therapeutic interventions combating biofilm-related infections in orthopaedics	16
Induction heating combined with antibiotics or SAAP-148 effectively reduces biofilm-embedded Staphylococcus aureus on a fracture-related implant mimic	16
Longitudinal monitoring of bone remodelling activity around the acetabular cup after total hip arthroplasty using 18F-fluoride PET/CT scans	16
An analysis of the medial femoral condyle flap anatomy and the involvement of different tissue components for the reconstruction of complex defects	16
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope	15
Diathermy and bone sawing are high aerosol yield procedures	15
Proximal humerus fractures – epidemiology, comparison of mortality rates after surgical versus non-surgical treatment, and analysis of risk factors based on Medicare registry data	15
Do preoperative intra-articular injections of corticosteroids or hyaluronic acid increase the risk of infection after total knee arthroplasty? A meta-analysis	15
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary hip arthroplasty in England and Wales	14
Infographic: Osteoimmunology mechanism of osteonecrosis of the femoral head	14
siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc dege	14
Reviewer acknowledgement	14
Overcoming barriers to interdisciplinary research in engineering and orthopaedic surgery	14
HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice	13
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	13
Panoramic heat map for spatial distribution of necrotic lesions	13
Preoperative prediction for periprosthetic bone loss and individual evaluation of bisphosphonate effect after total hip arthroplasty using artificial intelligence	13
The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis	13
The role of AGEs in muscle ageing and sarcopenia	13
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	12
Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	12
Cystic lesions in osteoarthritis and osteonecrosis of the femoral head	12
Impact of tranexamic acid on the efficacy of vancomycin and meropenem against periprosthetic joint infections	12
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	12
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	11
Impact of elevated sclerostin levels on bone resorption	11
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	11
The effect of cement augmentation on pedicle screw fixation under various load cases	11

Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review	11
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	11
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	11
Corrigendum	11
Osteocyte-specific dentin matrix protein 1	10
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin	10
The reconstruction of critical bone loss	10
Evaluating upper leg muscle volume	10
Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	10
Effect of human adipose stem cell-derived mitochondrial transplantation on the activity of chronically injured anterior cruciate ligament cells	10
Basic research for ultrasound-guided injection into skeletal muscle lesions in an experimental animal model	10
Single-cell transcriptomics analysis of the healing process of ligament rupture	10
Factors associated with Achilles tendon re-rupture following operative fixation	10
Prioritization versus rationing of healthcare – elective surgery is not optional surgery	10
Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress	10
Effect of resistance training on satellite cells in old mice – a transcriptome study	10
Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency through pathways instated by increased expression of klotho	10
Type-I and -II collagens from bone and cartilage colocalize at the osteochondral cement line	10