OOIR: Observatory of International Research

Papers

(The TQCC of Bone & Joint Research is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis	45
Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg²⁺	44
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	42
Cobalt-induced cardiomyopathy – do circulating cobalt levels matter?	40
Diabetes – osteoarthritis and joint pain	37
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	32
Effect of surface matching mismatch of focal knee articular prosthetic on tibiofemoral contact stress using finite element analysis	31
The incidence of musculoskeletal injuries: a systematic review and meta-analysis	31
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	30
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	29
Reviewer acknowledgement	27
The primary stability of the femoral component in cemented single and twin peg Oxford unicompartmental knee arthroplasty under adverse conditions	26
Real time measurement of intramuscular pH during routine knee arthroscopy using a tourniquet	26
Osteoblast function in patients with idiopathic osteonecrosis of the femoral head	26
Sonodynamic effect based on vancomycin-loaded microbubbles or meropenem-loaded microbubbles enhances elimination of different biofilms and bactericidal efficacy	25
Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density	24
Astragalus polysaccharide promotes osteogenic differentiation of human bone marrow derived mesenchymal stem cells by facilitating ANKFY1 expression through miR-760 inhibition	23
Comparison of ligamentization potential between anterior cruciate ligament-derived cells and adipose-derived mesenchymal stem cells reseeded to acellularized tendon allograft	23
Fracture-related infection	23
Reviewer acknowledgement	22
Prognostic factors associated with failure of total elbow arthroplasty	21
The effect of anti-retroviral therapy on fracture healing	21
Enhanced antibiofilm potential of low-intensity pulsed ultrasound combined with 0.35% povidone-iodine in a rat model of periprosthetic joint infection	21
Appropriate sagittal positioning of femoral components in total knee arthroplasty to prevent fracture and loosening	21
Guanylate cyclase promotes osseointegration by inhibiting oxidative stress and inflammation in aged rats with iron overload	20

Efficacy of a saline wash plus vancomycin/tobramycin-doped PVA composite (PVA-VAN/TOB-P) in a mouse pouch infection model implanted with 3D-printed porous titanium cylinders	20
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	19
Implant retention in a rabbit model of fracture-related infection	19
Infographic: Chongqing technique	19
Intermittent parathyroid hormone increases stability and improves osseointegration of initially unstable implants	19
Patient-reported outcome measures used in patients undergoing total knee arthroplasty	17
GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis	17
Artificial intelligence in orthopaedics	17
Comparison of periprosthetic femoral fracture torque and strain pattern of three types of femoral components in experimental model	17
microRNA-136-5p from bone marrow mesenchymal stem cell-derived exosomes facilitates fracture healing by targeting LRP4 to activate the Wnt/β-catenin pathway	17
Can barb thread design improve the pullout strength of bone screws?	17
Three orthopaedic operations, over 1,000 randomized controlled trials, in over 100,000 patients	17
The interactions of macrophages, lymphocytes, and mesenchymal stem cells during bone regeneration	16
The effect of cement augmentation on pedicle screw fixation under various load cases	16
Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase	15
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	15
Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	15
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways	15
Intra-articular versus systemic vancomycin for the treatment of periprosthetic joint infection after debridement and spacer implantation in a rat model	15
Advanced oxidation protein products induce inflammatory responses and invasive behaviour in fibroblast-like synoviocytes via the RAGE-NF-κB pathway	15
Risk factors for unplanned reoperation after corrective surgery for adult spinal deformity	14
A survey on the usage of decellularized tissues in orthopaedic clinical trials	14
The role of accelerated growth plate fusion in the absence of SOCS2 on osteoarthritis vulnerability	14
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	13
What is the appropriate extended duration of antibiotic prophylaxis after two-stage revision for chronic PJI?	13
Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis	13
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	13
Infographic: Three key elements of kinematic alignment total knee arthroplasty for clarified understanding of its approaches	13
Peripheral nerves in the tibial subchondral bone	13
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	13
Intra-articular celecoxib improves knee extension regardless of surgical release in a rabbit model of arthrofibrosis	13
Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway	12
Mild aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL)-type reactions also present in patients with failed knee prostheses	12
Reviewer acknowledgement	12
Osteoimmunology and osteonecrosis of the femoral head	12
Radiodynamic therapy with acridine orange local administration as a new treatment option for primary and secondary bone tumours	12
Can severity of trunnion damage be estimated by visual inspection alone?	12
Serum albumin-to-globulin ratio and CRP-to-albumin ratio did not outperform serum CRP in diagnosing periprosthetic joint infections	11
The delivery of an emergency audit response to a communicable disease outbreak can inform future orthopaedic investigations and clinical practice	11
The metabolic equivalent of task score	11
Identification and experimental validation of key extracellular proteins as potential targets in intervertebral disc degeneration	11
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	11
Improving the cementation of the tibial component in knee arthroplasty	11
Cortical bone thickness of the distal radius predicts the local bone mineral density	11
Stable polyethylene inlay fixation and low polyethylene wear rate in fixed-bearing total knee arthroplasty at five to six years’ follow-up	10
Detection and utility of cell-free and circulating tumour DNA in bone and soft-tissue sarcomas	10
Hsa_circ_0066523 promotes the proliferation and osteogenic differentiation of bone mesenchymal stem cells by repressing PTEN	10
Shared genetic liability between major depressive disorder and osteoarthritis	10
Prosthetic spacers in two-stage revision for knee periprosthetic joint infection achieve better function and similar infection control	10
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	10

Long-term patient-related quality of life after fracture-related infections of the long bones	10
Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage	9
Effect of the additional anteroposterior blocking screw on nail/medullary canal mismatch after cephalomedullary nailing in unstable pertrochanteric fracture	9
Disease-modifying agents in osteoarthritis: where are we now and what does the future hold?	9
A radio- and fluorescently labelled tracer for imaging and quantification of bacterial infection on orthopaedic prostheses	9
Long noncoding RNA H19 alleviates inflammation in osteoarthritis through interactions between TP53, IL-38, and IL-36 receptor	9
Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	9
MicroRNA-486 promotes a more catabolic phenotype in chondrocyte-like cells by targeting SIRT6	9
Impact of racial disparities and insurance status in patients with bone sarcomas in the USA	8
N,N-Dimethylformamide inhibits high glucose-induced osteoporosis via attenuating MAPK and NF-κB signalling	8
Meniscus cell lysate induces mitochondrial dysfunction of fibroblast-like synoviocytes via upregulating ANT3 in osteoarthritis	8
Sonographic bridging callus at six weeks following displaced midshaft clavicle fracture can accurately predict healing	8
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	8
Effects of focused continuous pulsed electromagnetic field therapy on early tendon-to-bone healing	8
LINC01089 governs the miR-1287-5p/HSPA4 axis to negatively regulate osteogenic differentiation of mesenchymal stem cells	8
Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	8
Robotic-arm assisted THA can achieve precise cup positioning in developmental dysplasia of the hip	8
The accuracy of restoration of femoral head centre of rotation in the anteroposterior plane after uncemented total hip arthroplasty	8
The function of lncRNAs in the pathogenesis of osteoarthritis	8
MicroRNA-183attenuates osteoarthritic pain by inhibiting theTGFα-mediatedCCL2/CCR2signalling axis	8
Alcohol-induced inhibition of bone formation and neovascularization contributes to the failure of fracture healing via the miR-19a-3p/FOXF2 axis	8
The risk of tibial eminence avulsion fracture with bi-unicondylar knee arthroplasty	8
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	8
3D-printed titanium implant combined with interleukin 4 regulates ordered macrophage polarization to promote bone regeneration and angiogenesis	8