OOIR: Observatory of International Research

Papers

(The TQCC of Bone & Joint Research is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	170
Prognostic factors associated with failure of total elbow arthroplasty	94
Enhancing precision in limb-salvage surgery	92
Candy box technique with sutures and Nice knot	91
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	74
Ultrasound combined with voriconazole for treating acute fungal periprosthetic joint infection caused by Candida albicans	56
Ontogenetic changes in femoral morphology and joint loads in children	53
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	49
The effect of impaction energy and bone quality on cementless femoral implant fixation and femoral periprosthetic fracture risk	47
The future of osteoarthritis treatment: exploring the potential of exosomes from adipose tissue-derived stem cells	36
Mental health implications of fracture-related infections	34
Managing large type 2a bone defects from osteoporotic tibial plateau fractures	32
Feasibility and reliability of shear wave elastography-guided collateral ligament balancing during total knee arthroplasty	32
Can severity of trunnion damage be estimated by visual inspection alone?	32
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	30
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	30
CDK12 mediates the inhibition effect of mechanical unloading on osteoblast proliferation by regulating RNAPII transcription activation	29
Subluxation-induced liner adhesion and the effect of impaction to prevent liner dislocation in ceramic hip arthroplasty	29
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	27
Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	27
Diagnosing periprosthetic joint infections	26
Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis	25
Osteochondral lesions of talus	25
Discogenic pain in lumbar vertebra	25
Prediction of implant failure risk due to periprosthetic femoral fracture after primary elective total hip arthroplasty	24

Therapeutic potential of IκB kinase epsilon inhibition in preventing meniscal degeneration of early osteoarthritis	24
Reviewer acknowledgement	24
FGF9 attenuates osteoarthritis progression through the NRF2/GPX3 antioxidant axis	23
Application of loaded graphene oxide biomaterials in the repair and treatment of bone defects	22
The CREB1 inhibitor 666-15 maintains cartilage homeostasis and mitigates osteoarthritis progression	22
Finite element analysis safety of tibial cortex transverse transport	21
The role of cells and signal pathways in subchondral bone in osteoarthritis	21
Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway	21
Beyond the surface: anterior cruciate ligament assessment in knee osteoarthritis	21
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats	20
Navigating change: upholding scientific integrity in an era of innovation	20
High-resolution peripheral quantitative CT of the proximal fifth metatarsal reveals microstructural similarity between Lawrence and Botte zones I and II	19
Future registry research	19
Hederagenin promotes SIRT6 to attenuate epidural scar formation by aggravating PRMT1 deacetylation	18
Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27^kip1 pathway	18
A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis	18
Transcriptome-wide association study identifies new susceptibility genes for degenerative cervical spondylosis	18
Oxygen tension alters cartilage redox balance in response to traumatic impact	18
Detection limitations of bacteria in tissue samples	17
High-intensity running exercise promotes knee meniscal damage via the PI3K/AKT/mTOR axis	17
Functionalizing biomaterials for osseointegration – microRNAs at the crossroads of bone formation and immune modulation	17
Detection of rare microorganisms in bone and joint infections by metagenomic next-generation sequencing	17
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages	16
Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing	16
Biomechanical study of screw-supported prosthesis in acetabular revision	16
CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro	16
An analysis of the medial femoral condyle flap anatomy and the involvement of different tissue components for the reconstruction of complex defects	16
Longitudinal monitoring of bone remodelling activity around the acetabular cup after total hip arthroplasty using 18F-fluoride PET/CT scans	15
Current therapeutic interventions combating biofilm-related infections in orthopaedics	15
Diathermy and bone sawing are high aerosol yield procedures	15
Induction heating combined with antibiotics or SAAP-148 effectively reduces biofilm-embedded Staphylococcus aureus on a fracture-related implant mimic	14
Identification of age-related genes in rotator cuff tendon	14
siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc dege	14
Proximal humerus fractures – epidemiology, comparison of mortality rates after surgical versus non-surgical treatment, and analysis of risk factors based on Medicare registry data	14
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope	14
The diagnostic accuracy of serum and synovial inflammatory markers in chronic periprosthetic joint infection among anaemic patients	13
More severe joint disease and lower patient oxygenation are associated with less corrosive in vivo synovial fluid in patients with knee osteoarthritis	13
Overcoming barriers to interdisciplinary research in engineering and orthopaedic surgery	13
Panoramic heat map for spatial distribution of necrotic lesions	13
Reviewer acknowledgement	13
Clinical study on the 3D morphology and mechanical factors of lumbar facet joints in patients with degenerative lumbar spondylolisthesis	12
The role of AGEs in muscle ageing and sarcopenia	12
Preoperative prediction for periprosthetic bone loss and individual evaluation of bisphosphonate effect after total hip arthroplasty using artificial intelligence	12
HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice	12
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary hip arthroplasty in England and Wales	12
Cystic lesions in osteoarthritis and osteonecrosis of the femoral head	12
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	11
Corrigendum	11
Three decades of transformation: a bibliometric study of gender and geographic trends in international orthopaedic journal publications	11
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	11

Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	11
Impact of tranexamic acid on the efficacy of vancomycin and meropenem against periprosthetic joint infections	11
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	11
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	11
Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	11
Vascular remodelling and fibrotic changes in the joint capsule during periprosthetic knee infections	10
Corrigendum	10
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	10
Patellar luxation causes abnormal mechanical loading and joint destruction in the femoral-tibial joint	10
Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review	10
Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	10
Impact of elevated sclerostin levels on bone resorption	10
Anatomy changes, signalling pathways, and clinical treatment after ankle sprain	9
Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress	9
Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection	9
Increased local bone turnover in patients with chronic periprosthetic joint infection	9
Type-I and -II collagens from bone and cartilage colocalize at the osteochondral cement line	9
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	9
Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency through pathways instated by increased expression of klotho	9
Single-cell transcriptomics analysis of the healing process of ligament rupture	9
Antiosteoporotic treatment promotes tendon-to-bone healing after rotator cuff repair	9
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin	9
Factors associated with Achilles tendon re-rupture following operative fixation	9
Persistent bone and muscle deficits after anterior cruciate ligament reconstruction	9
Effect of human adipose stem cell-derived mitochondrial transplantation on the activity of chronically injured anterior cruciate ligament cells	9
Femoral impingement in maximal hip flexion is anterior-inferior distal to the cam deformity in femoroacetabular impingement patients with femoral retroversion	9