OOIR: Observatory of International Research

Papers

(The TQCC of Bone & Joint Research is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis	59
Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg²⁺	54
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	53
Diabetes – osteoarthritis and joint pain	51
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	49
Effect of surface matching mismatch of focal knee articular prosthetic on tibiofemoral contact stress using finite element analysis	40
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	38
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	35
Reviewer acknowledgement	34
The primary stability of the femoral component in cemented single and twin peg Oxford unicompartmental knee arthroplasty under adverse conditions	32
Osteoblast function in patients with idiopathic osteonecrosis of the femoral head	31
Real time measurement of intramuscular pH during routine knee arthroscopy using a tourniquet	30
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	29
Sonodynamic effect based on vancomycin-loaded microbubbles or meropenem-loaded microbubbles enhances elimination of different biofilms and bactericidal efficacy	29
Astragalus polysaccharide promotes osteogenic differentiation of human bone marrow derived mesenchymal stem cells by facilitating ANKFY1 expression through miR-760 inhibition	27
Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density	27
Infographic: Chongqing technique	26
Comparison of ligamentization potential between anterior cruciate ligament-derived cells and adipose-derived mesenchymal stem cells reseeded to acellularized tendon allograft	26
Reviewer acknowledgement	25
The effect of anti-retroviral therapy on fracture healing	24
Prognostic factors associated with failure of total elbow arthroplasty	23
Enhanced antibiofilm potential of low-intensity pulsed ultrasound combined with 0.35% povidone-iodine in a rat model of periprosthetic joint infection	23
Guanylate cyclase promotes osseointegration by inhibiting oxidative stress and inflammation in aged rats with iron overload	22
Appropriate sagittal positioning of femoral components in total knee arthroplasty to prevent fracture and loosening	22
Efficacy of a saline wash plus vancomycin/tobramycin-doped PVA composite (PVA-VAN/TOB-P) in a mouse pouch infection model implanted with 3D-printed porous titanium cylinders	22

Implant retention in a rabbit model of fracture-related infection	21
The effect of cement augmentation on pedicle screw fixation under various load cases	21
Melatonin alleviates senile osteoporosis by regulating autophagy and enhancing fracture healing in aged mice	20
Risk factors for unplanned reoperation after corrective surgery for adult spinal deformity	20
Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis	20
Artificial intelligence in orthopaedics	20
Three orthopaedic operations, over 1,000 randomized controlled trials, in over 100,000 patients	19
microRNA-136-5p from bone marrow mesenchymal stem cell-derived exosomes facilitates fracture healing by targeting LRP4 to activate the Wnt/β-catenin pathway	19
GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis	19
Comparison of periprosthetic femoral fracture torque and strain pattern of three types of femoral components in experimental model	19
Intra-articular versus systemic vancomycin for the treatment of periprosthetic joint infection after debridement and spacer implantation in a rat model	18
The interactions of macrophages, lymphocytes, and mesenchymal stem cells during bone regeneration	18
Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	17
Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase	17
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways	17
Fracture-related infection	17
Advanced oxidation protein products induce inflammatory responses and invasive behaviour in fibroblast-like synoviocytes via the RAGE-NF-κB pathway	17
The role of accelerated growth plate fusion in the absence of SOCS2 on osteoarthritis vulnerability	15
A survey on the usage of decellularized tissues in orthopaedic clinical trials	14
Mental health implications of fracture-related infections	13
Intra-articular celecoxib improves knee extension regardless of surgical release in a rabbit model of arthrofibrosis	13
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	13
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	13
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	13
What is the appropriate extended duration of antibiotic prophylaxis after two-stage revision for chronic PJI?	13
Cobalt-induced cardiomyopathy – do circulating cobalt levels matter?	13
Erratum	13
The incidence of musculoskeletal injuries: a systematic review and meta-analysis	13
The effect of metaphyseal holes and interposition material on the longitudinal growth stimulation of long bones in a rabbit model	12
Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway	12
Infographic: Three key elements of kinematic alignment total knee arthroplasty for clarified understanding of its approaches	12
Can severity of trunnion damage be estimated by visual inspection alone?	12
LINC01089 governs the miR-1287-5p/HSPA4 axis to negatively regulate osteogenic differentiation of mesenchymal stem cells	12
Intermittent parathyroid hormone increases stability and improves osseointegration of initially unstable implants	12
Reviewer acknowledgement	12
Peripheral nerves in the tibial subchondral bone	12
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	11
Development of a novel rat long-bone nonunion model and efficacy evaluation of a prostaglandin EP4 selective agonist (AKDS001) combined with iliac bone grafting	11
Serum albumin-to-globulin ratio and CRP-to-albumin ratio did not outperform serum CRP in diagnosing periprosthetic joint infections	11
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	11
The metabolic equivalent of task score	11
Identification and experimental validation of key extracellular proteins as potential targets in intervertebral disc degeneration	11
Cortical bone thickness of the distal radius predicts the local bone mineral density	11
The delivery of an emergency audit response to a communicable disease outbreak can inform future orthopaedic investigations and clinical practice	11
The antimicrobial properties of exogenous copper in human synovial fluid against Staphylococcus aureus	11
Stable polyethylene inlay fixation and low polyethylene wear rate in fixed-bearing total knee arthroplasty at five to six years’ follow-up	10
Disease-modifying agents in osteoarthritis: where are we now and what does the future hold?	10
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	10
Hsa_circ_0066523 promotes the proliferation and osteogenic differentiation of bone mesenchymal stem cells by repressing PTEN	10
Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage	10

Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	10
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	10
Robotic-arm assisted THA can achieve precise cup positioning in developmental dysplasia of the hip	10
The risk of tibial eminence avulsion fracture with bi-unicondylar knee arthroplasty	9
Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	9
Meniscus cell lysate induces mitochondrial dysfunction of fibroblast-like synoviocytes via upregulating ANT3 in osteoarthritis	9
Effect of the additional anteroposterior blocking screw on nail/medullary canal mismatch after cephalomedullary nailing in unstable pertrochanteric fracture	9
Alcohol-induced inhibition of bone formation and neovascularization contributes to the failure of fracture healing via the miR-19a-3p/FOXF2 axis	9
MicroRNA-486 promotes a more catabolic phenotype in chondrocyte-like cells by targeting SIRT6	9
Corrigenda	8
Corrigenda	8
Diagnosing periprosthetic joint infections	8
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	8
Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review	8
MicroRNA-183attenuates osteoarthritic pain by inhibiting theTGFα-mediatedCCL2/CCR2signalling axis	8
Low-grade systemic inflammation, but not neuroinflammation, is associated with 12-month postoperative outcome after total hip arthroplasty in patients with painful osteoarthritis	8
Prosthetic spacers in two-stage revision for knee periprosthetic joint infection achieve better function and similar infection control	8
Radiodynamic therapy with acridine orange local administration as a new treatment option for primary and secondary bone tumours	8
Bi-unicondylar arthroplasty	8
Shared genetic liability between major depressive disorder and osteoarthritis	8
Effects of focused continuous pulsed electromagnetic field therapy on early tendon-to-bone healing	8
Corrigendum	8
3D-printed titanium implant combined with interleukin 4 regulates ordered macrophage polarization to promote bone regeneration and angiogenesis	8