Bone & Joint Research

Article	Citations
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	92
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	64
Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density	62
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	56
Mental health implications of fracture-related infections	51
Comparison of periprosthetic femoral fracture torque and strain pattern of three types of femoral components in experimental model	49
Candy box technique with sutures and Nice knot	48
Intra-articular celecoxib improves knee extension regardless of surgical release in a rabbit model of arthrofibrosis	39
Bi-unicondylar arthroplasty	38
Prognostic factors associated with failure of total elbow arthroplasty	38
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	33
Effect of the additional anteroposterior blocking screw on nail/medullary canal mismatch after cephalomedullary nailing in unstable pertrochanteric fracture	33
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	32
Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	32
The metabolic equivalent of task score	29
Can severity of trunnion damage be estimated by visual inspection alone?	29
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	28
Diagnosing periprosthetic joint infections	27
Finite element analysis safety of tibial cortex transverse transport	26
Osteochondral lesions of talus	26
The CREB1 inhibitor 666-15 maintains cartilage homeostasis and mitigates osteoarthritis progression	24
Sheep condyle model evaluation of bone marrow cell concentrate combined with a scaffold for repair of large osteochondral defects	24
Prediction of implant failure risk due to periprosthetic femoral fracture after primary elective total hip arthroplasty	24
Preoperative measures of bone mineral density from digital wrist radiographs	23
Comprehensive analysis of pathological changes in hip joint capsule of patients with developmental dysplasia of the hip	23

Application of loaded graphene oxide biomaterials in the repair and treatment of bone defects	22
The role of cells and signal pathways in subchondral bone in osteoarthritis	21
Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis	21
Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway	21
Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing	20
CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro	20
Beyond the surface: anterior cruciate ligament assessment in knee osteoarthritis	20
Future registry research	19
A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis	19
Histone deacetylase inhibitors attenuated interleukin-1β-induced chondrogenesis inhibition in synovium-derived mesenchymal stem cells of the temporomandibular joint	19
Detection of rare microorganisms in bone and joint infections by metagenomic next-generation sequencing	18
Tibial cortex transverse transport accelerates wound healing via enhanced angiogenesis and immunomodulation	18
Transcriptome-wide association study identifies new susceptibility genes for degenerative cervical spondylosis	18
Human acellular amniotic membrane scaffolds encapsulating juvenile cartilage fragments accelerate the repair of rabbit osteochondral defects	18
Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27kip1 pathway	17
Hederagenin promotes SIRT6 to attenuate epidural scar formation by aggravating PRMT1 deacetylation	17
Detection limitations of bacteria in tissue samples	16
Induction heating combined with antibiotics or SAAP-148 effectively reduces biofilm-embedded Staphylococcus aureus on a fracture-related implant mimic	16
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice	16
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages	16
siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc dege	16
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats	16
Ultrasound-targeted simvastatin-loaded microbubble destruction promotes OA cartilage repair by modulating the cholesterol efflux pathway mediated by PPARγ in rabbits	16
Diathermy and bone sawing are high aerosol yield procedures	15
A large-scale genetic correlation scan between rheumatoid arthritis and human plasma protein	15
Identification of age-related genes in rotator cuff tendon	15
Current therapeutic interventions combating biofilm-related infections in orthopaedics	14
Proximal humerus fractures – epidemiology, comparison of mortality rates after surgical versus non-surgical treatment, and analysis of risk factors based on Medicare registry data	14
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope	14
Do preoperative intra-articular injections of corticosteroids or hyaluronic acid increase the risk of infection after total knee arthroplasty? A meta-analysis	14
Capsular ligaments provide a passive stabilizing force to protect the hip against edge loading	13
Reviewer acknowledgement	13
Panoramic heat map for spatial distribution of necrotic lesions	13
Development and validation of a modularized external fixator for generating standardized fracture healing micromotions in rats	13
Infographic: Osteoimmunology mechanism of osteonecrosis of the femoral head	13
HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice	13
The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis	12
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	12
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	12
The role of AGEs in muscle ageing and sarcopenia	12
Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	12
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	12
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary hip arthroplasty in England and Wales	12
Preoperative prediction for periprosthetic bone loss and individual evaluation of bisphosphonate effect after total hip arthroplasty using artificial intelligence	12
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	12
Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review	11
The effect of cement augmentation on pedicle screw fixation under various load cases	11
Corrigendum	11
Impact of tranexamic acid on the efficacy of vancomycin and meropenem against periprosthetic joint infections	11
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	11

Osteocyte-specific dentin matrix protein 1	10
Single-cell transcriptomics analysis of the healing process of ligament rupture	10
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	10
Human osteoblasts obtained from distinct periarticular sites demonstrate differences in biological function in vitro	10
Type-I and -II collagens from bone and cartilage colocalize at the osteochondral cement line	10
Femoral impingement in maximal hip flexion is anterior-inferior distal to the cam deformity in femoroacetabular impingement patients with femoral retroversion	10
Impact of elevated sclerostin levels on bone resorption	10
Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	10
Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress	10
Basic research for ultrasound-guided injection into skeletal muscle lesions in an experimental animal model	10
Prioritization versus rationing of healthcare – elective surgery is not optional surgery	10
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	10
Factors associated with Achilles tendon re-rupture following operative fixation	10
Increased local bone turnover in patients with chronic periprosthetic joint infection	9
Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection	9
Exercise modifies the disease-relevant gut microbial shifts in post-traumatic osteoarthritis rats	9
Evaluation of the causal relationship between 28 circulating biomarkers and osteoarthritis	9
Adenosine, lidocaine, and magnesium therapy augments joint tissue healing following experimental anterior cruciate ligament rupture and reconstruction	9
Effect of resistance training on satellite cells in old mice – a transcriptome study	9
The role of Staphylococcus aureus small colony variants in intraosseous invasion and colonization in periprosthetic joint infection	9
Evaluating upper leg muscle volume	9
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin	9
Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency through pathways instated by increased expression of klotho	9
The reconstruction of critical bone loss	9
Importance of posterior tibial slope in joint kinematics with an anterior cruciate ligament-deficient knee	8
Qualitative methods: the missing link in orthopaedic research	8
Clinical, oncological, and prognostic differences of patients with subsequent skeletal-related events in bone metastases	8
Growth differentiation factor 15 as a potential diagnostic biomarker for rheumatoid arthritis	8
Rifampicin restores extracellular organic matrix formation and mineralization of osteoblasts after intracellular Staphylococcus aureus infection	8
Effectiveness of mechanical cleaning, antibiotics, and induction heating on eradication of Staphylococcus aureus in mature biofilms	8
Increased loading of the lateral knee compartment in the unamputated knee during gait in people with unilateral transfemoral/through-knee amputations	8
Overcoming the detrimental impact of volumetric muscle loss on segmental fracture healing via the induced membrane technique	8
The impact of cementing technique in polished taper fit hip stems	8
Long-term hypoxic atmosphere enhances the stemness, immunoregulatory functions, and therapeutic application of human umbilical cord mesenchymal stem cells	8
Effects of high antibiotic concentrations applied to continuous local antibiotic perfusion on human bone tissue-derived cells	8
PEDF peptide plus hyaluronic acid stimulates cartilage regeneration in osteoarthritis via STAT3-mediated chondrogenesis	8
Development and validation of a novel prediction model for osteoporosis	8
The degenerated glenohumeral joint	8
The interactions of macrophages, lymphocytes, and mesenchymal stem cells during bone regeneration	7
The primary stability of the femoral component in cemented single and twin peg Oxford unicompartmental knee arthroplasty under adverse conditions	7
Identification of the molecular link: STAT3 is a shared key gene linking postmenopausal osteoporosis and sarcopenia	7
Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis	7
Efficacy of a saline wash plus vancomycin/tobramycin-doped PVA composite (PVA-VAN/TOB-P) in a mouse pouch infection model implanted with 3D-printed porous titanium cylinders	7
Intermittent parathyroid hormone increases stability and improves osseointegration of initially unstable implants	7
Astragalus polysaccharide promotes osteogenic differentiation of human bone marrow derived mesenchymal stem cells by facilitating ANKFY1 expression through miR-760 inhibition	7
Reviewer acknowledgement	7
Immunomodulatory role of T helper cells in rheumatoid arthritis	7
Intra-articular versus systemic vancomycin for the treatment of periprosthetic joint infection after debridement and spacer implantation in a rat model	7
Infographic: Chongqing technique	7
What is the appropriate extended duration of antibiotic prophylaxis after two-stage revision for chronic PJI?	7
Infographic: Three key elements of kinematic alignment total knee arthroplasty for clarified understanding of its approaches	7
Alcohol-induced inhibition of bone formation and neovascularization contributes to the failure of fracture healing via the miR-19a-3p/FOXF2 axis	7
TGF-β1 derived from macrophages contributes to load-induced tendon-bone healing in the murine rotator cuff repair model by promoting chondrogenesis	7
Reviewer acknowledgement	7
Osteoblast function in patients with idiopathic osteonecrosis of the femoral head	7
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways	7
Stable polyethylene inlay fixation and low polyethylene wear rate in fixed-bearing total knee arthroplasty at five to six years’ follow-up	6
Damage control orthopaedics is associated with impaired fracture healing and delayed recovery in a rodent model of severe multiple trauma	6
A bilayer scaffold of collagen and nanohydroxyapatite promotes osteochondral defect repair in rabbit knee joints	6
Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors	6
Volume and location of bone regeneration after autologous expanded mesenchymal stromal cells in hip osteonecrosis	6
Meniscus cell lysate induces mitochondrial dysfunction of fibroblast-like synoviocytes via upregulating ANT3 in osteoarthritis	6
LncRNA PCBP1-AS1 induces osteoporosis by sponging miR-126-5p/PAK2 axis	6
Retraction notice	6
Repetitive combined doses of bacteriophages and gentamicin protect against Staphylococcus aureus implant-related infections in Galleria mellonella	6
Terminology of bone and joint infection	6
Infographic: Total hip arthroplasty in early osteoarthritis	6
The accuracy of restoration of femoral head centre of rotation in the anteroposterior plane after uncemented total hip arthroplasty	6
Robotic-arm assisted THA can achieve precise cup positioning in developmental dysplasia of the hip	6
Regeneration of injured articular cartilage using the recombinant human amelogenin protein	6
The IMPACT of COVID-19 on trauma & orthopaedic surgery provides lessons for future communicable disease outbreaks	6
Are we doing the right surgical trials?	6
Platelets mediate trained immunity against bone and joint infections in a mouse model	5
Rapid multiplex micro-ELISA assay for simultaneous measurement of synovial biomarkers	5
Effect of secretory leucocyte protease inhibitor on early tendon-to-bone healing after anterior cruciate ligament reconstruction in a rat model	5
Multiple roles of ALK3 in osteoarthritis	5
Identification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone	5
Development and validation of an open-source tool for opportunistic screening of osteoporosis from hip CT images	5
Monomeric CRP regulates inflammatory responses in human intervertebral disc cells	5
Cyclin D1 mediates pain behaviour in a rat model of breast cancer-induced bone pain by a mechanism involving regulation of the proliferation of spinal microglia	5

Wound fluid ceftriaxone concentrations after local application with calcium sulphate as carrier material in the treatment of orthopaedic device-associated hip infections	5
The role of BioFire Joint Infection Panel in diagnosing periprosthetic hip and knee joint infections in patients with unclear conventional microbiological results	5
BRD4promotes heterotopic ossification through upregulation of LncRNA MANCR	5
Meaningful values in the Short Form Health Survey-36 after total knee arthroplasty – an alternative to the EuroQol five-dimension index as a measure for health-related quality of life	5
Appraising causal risk and protective factors for rheumatoid arthritis	5
Predicted waiting times for orthopaedic surgery	5
Cytokines and regulatory T cells in ankylosing spondylitis	5
Upregulated ribosome pathway plays a key role in HDAC4, improving the survival rate and biofunction of chondrocytes	5
Enhancement of hyaline cartilage and subchondral bone regeneration in a rat osteochondral defect model through focused extracorporeal shockwave therapy	5
Outcomes following surgical management of femoroacetabular impingement: a systematic review and meta-analysis of different surgical techniques	5
Knee kinematics during staircase descent	5
Melatonin induces RAW264.7 cell apoptosis via the BMAL1/ROS/MAPK-p38 pathway to improve postmenopausal osteoporosis	5
Clinical outcomes following intra-articular injection of autologous adipose-derived mesenchymal stem cells for the treatment of osteoarthritis in dogs characterized by weight-bearing asymmetry	5
Repurposing the diuretic benzamil as an anti-osteosarcoma agent that acts by suppressing integrin/FAK/STAT3 signalling and compromising mitochondrial function	5
Changes in the shape of the lumbar curve during growth	5
3D printing in orthopaedic surgery: a scoping review of randomized controlled trials	5
Aberrant anabolism hinders constructive metabolism of chondrocytes by pharmacotherapy in osteoarthritis	5
Effect of treadmill training on fibrocartilage complex repair in tendon-bone insertion healing in the postinflammatory stage	5
The Clinical Practice Integration of Artificial Intelligence (CPI-AI) framework	5
Concomitant osteochondral lesion of the talus affects in vivo ankle kinetics in patients with chronic ankle instability	5
Clinical efficacy and safety of P-15 peptide enhanced bone graft substitute in surgical bone regenerative procedures in adult maxillofacial, spine, and trauma patients	5
Pulsed Nd:YAG laser therapy accelerates fracture healing in a rat femoral osteotomy model	4
A survey on the usage of decellularized tissues in orthopaedic clinical trials	4
Tendon healing: a concise review on cellular and molecular mechanisms with a particular focus on the Achilles tendon	4
Enhanced antibiofilm potential of low-intensity pulsed ultrasound combined with 0.35% povidone-iodine in a rat model of periprosthetic joint infection	4
The full radiostereometric analysis migration pattern of tibial components is associated with aseptic loosening	4
GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis	4
The role of accelerated growth plate fusion in the absence of SOCS2 on osteoarthritis vulnerability	4
Bone turnover markers as surrogates of fracture healing after intramedullary fixation of tibia and femur fractures	4
Melatonin alleviates senile osteoporosis by regulating autophagy and enhancing fracture healing in aged mice	4
The influence of “kickstand” screws on the mechanical performance of a lateral distal femoral plate	4
Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage	4
Erratum	4
The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development	4
In vivo reduction of biofilm seeded on orthopaedic implants	4
Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis	4
Osteoimmunology and osteonecrosis of the femoral head	4