Bone & Joint Research

Article	Citations
Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis	59
Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2+	54
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	53
Diabetes – osteoarthritis and joint pain	51
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	49
Effect of surface matching mismatch of focal knee articular prosthetic on tibiofemoral contact stress using finite element analysis	40
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	38
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	35
Reviewer acknowledgement	34
The primary stability of the femoral component in cemented single and twin peg Oxford unicompartmental knee arthroplasty under adverse conditions	32
Osteoblast function in patients with idiopathic osteonecrosis of the femoral head	31
Real time measurement of intramuscular pH during routine knee arthroscopy using a tourniquet	30
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	29
Sonodynamic effect based on vancomycin-loaded microbubbles or meropenem-loaded microbubbles enhances elimination of different biofilms and bactericidal efficacy	29
Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density	27
Astragalus polysaccharide promotes osteogenic differentiation of human bone marrow derived mesenchymal stem cells by facilitating ANKFY1 expression through miR-760 inhibition	27
Comparison of ligamentization potential between anterior cruciate ligament-derived cells and adipose-derived mesenchymal stem cells reseeded to acellularized tendon allograft	26
Infographic: Chongqing technique	26
Reviewer acknowledgement	25
The effect of anti-retroviral therapy on fracture healing	24
Enhanced antibiofilm potential of low-intensity pulsed ultrasound combined with 0.35% povidone-iodine in a rat model of periprosthetic joint infection	23
Prognostic factors associated with failure of total elbow arthroplasty	23
Efficacy of a saline wash plus vancomycin/tobramycin-doped PVA composite (PVA-VAN/TOB-P) in a mouse pouch infection model implanted with 3D-printed porous titanium cylinders	22
Guanylate cyclase promotes osseointegration by inhibiting oxidative stress and inflammation in aged rats with iron overload	22
Appropriate sagittal positioning of femoral components in total knee arthroplasty to prevent fracture and loosening	22

The effect of cement augmentation on pedicle screw fixation under various load cases	21
Implant retention in a rabbit model of fracture-related infection	21
Artificial intelligence in orthopaedics	20
Melatonin alleviates senile osteoporosis by regulating autophagy and enhancing fracture healing in aged mice	20
Risk factors for unplanned reoperation after corrective surgery for adult spinal deformity	20
Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis	20
microRNA-136-5p from bone marrow mesenchymal stem cell-derived exosomes facilitates fracture healing by targeting LRP4 to activate the Wnt/β-catenin pathway	19
GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis	19
Comparison of periprosthetic femoral fracture torque and strain pattern of three types of femoral components in experimental model	19
Three orthopaedic operations, over 1,000 randomized controlled trials, in over 100,000 patients	19
The interactions of macrophages, lymphocytes, and mesenchymal stem cells during bone regeneration	18
Intra-articular versus systemic vancomycin for the treatment of periprosthetic joint infection after debridement and spacer implantation in a rat model	18
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways	17
Fracture-related infection	17
Advanced oxidation protein products induce inflammatory responses and invasive behaviour in fibroblast-like synoviocytes via the RAGE-NF-κB pathway	17
Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	17
Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase	17
The role of accelerated growth plate fusion in the absence of SOCS2 on osteoarthritis vulnerability	15
A survey on the usage of decellularized tissues in orthopaedic clinical trials	14
Cobalt-induced cardiomyopathy – do circulating cobalt levels matter?	13
Erratum	13
The incidence of musculoskeletal injuries: a systematic review and meta-analysis	13
Mental health implications of fracture-related infections	13
Intra-articular celecoxib improves knee extension regardless of surgical release in a rabbit model of arthrofibrosis	13
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	13
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	13
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	13
What is the appropriate extended duration of antibiotic prophylaxis after two-stage revision for chronic PJI?	13
Reviewer acknowledgement	12
Peripheral nerves in the tibial subchondral bone	12
The effect of metaphyseal holes and interposition material on the longitudinal growth stimulation of long bones in a rabbit model	12
Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway	12
Infographic: Three key elements of kinematic alignment total knee arthroplasty for clarified understanding of its approaches	12
Can severity of trunnion damage be estimated by visual inspection alone?	12
LINC01089 governs the miR-1287-5p/HSPA4 axis to negatively regulate osteogenic differentiation of mesenchymal stem cells	12
Intermittent parathyroid hormone increases stability and improves osseointegration of initially unstable implants	12
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	11
The metabolic equivalent of task score	11
Identification and experimental validation of key extracellular proteins as potential targets in intervertebral disc degeneration	11
Cortical bone thickness of the distal radius predicts the local bone mineral density	11
The delivery of an emergency audit response to a communicable disease outbreak can inform future orthopaedic investigations and clinical practice	11
The antimicrobial properties of exogenous copper in human synovial fluid against Staphylococcus aureus	11
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	11
Development of a novel rat long-bone nonunion model and efficacy evaluation of a prostaglandin EP4 selective agonist (AKDS001) combined with iliac bone grafting	11
Serum albumin-to-globulin ratio and CRP-to-albumin ratio did not outperform serum CRP in diagnosing periprosthetic joint infections	11
Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	10
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	10
Robotic-arm assisted THA can achieve precise cup positioning in developmental dysplasia of the hip	10
Stable polyethylene inlay fixation and low polyethylene wear rate in fixed-bearing total knee arthroplasty at five to six years’ follow-up	10
Disease-modifying agents in osteoarthritis: where are we now and what does the future hold?	10

Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	10
Hsa_circ_0066523 promotes the proliferation and osteogenic differentiation of bone mesenchymal stem cells by repressing PTEN	10
Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage	10
Alcohol-induced inhibition of bone formation and neovascularization contributes to the failure of fracture healing via the miR-19a-3p/FOXF2 axis	9
MicroRNA-486 promotes a more catabolic phenotype in chondrocyte-like cells by targeting SIRT6	9
The risk of tibial eminence avulsion fracture with bi-unicondylar knee arthroplasty	9
Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	9
Meniscus cell lysate induces mitochondrial dysfunction of fibroblast-like synoviocytes via upregulating ANT3 in osteoarthritis	9
Effect of the additional anteroposterior blocking screw on nail/medullary canal mismatch after cephalomedullary nailing in unstable pertrochanteric fracture	9
Radiodynamic therapy with acridine orange local administration as a new treatment option for primary and secondary bone tumours	8
Shared genetic liability between major depressive disorder and osteoarthritis	8
Bi-unicondylar arthroplasty	8
Corrigendum	8
Effects of focused continuous pulsed electromagnetic field therapy on early tendon-to-bone healing	8
3D-printed titanium implant combined with interleukin 4 regulates ordered macrophage polarization to promote bone regeneration and angiogenesis	8
Corrigenda	8
Diagnosing periprosthetic joint infections	8
Corrigenda	8
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	8
Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review	8
MicroRNA-183attenuates osteoarthritic pain by inhibiting theTGFα-mediatedCCL2/CCR2signalling axis	8
Prosthetic spacers in two-stage revision for knee periprosthetic joint infection achieve better function and similar infection control	8
Low-grade systemic inflammation, but not neuroinflammation, is associated with 12-month postoperative outcome after total hip arthroplasty in patients with painful osteoarthritis	8
A radio- and fluorescently labelled tracer for imaging and quantification of bacterial infection on orthopaedic prostheses	7
N,N-Dimethylformamide inhibits high glucose-induced osteoporosis via attenuating MAPK and NF-κB signalling	7
The accuracy of restoration of femoral head centre of rotation in the anteroposterior plane after uncemented total hip arthroplasty	7
Long noncoding RNA H19 alleviates inflammation in osteoarthritis through interactions between TP53, IL-38, and IL-36 receptor	7
Impact of racial disparities and insurance status in patients with bone sarcomas in the USA	7
Long-term patient-related quality of life after fracture-related infections of the long bones	7
LncRNA PCBP1-AS1 induces osteoporosis by sponging miR-126-5p/PAK2 axis	7
Osteoimmunology and osteonecrosis of the femoral head	7
Improving the cementation of the tibial component in knee arthroplasty	7
Detection and utility of cell-free and circulating tumour DNA in bone and soft-tissue sarcomas	7
Mild aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL)-type reactions also present in patients with failed knee prostheses	7
ATF3 as a potential diagnostic marker of early-stage osteoarthritis and its correlation with immune infiltration through bioinformatics analysis	6
Regeneration of injured articular cartilage using the recombinant human amelogenin protein	6
The epidemiology and direct healthcare costs of aseptic nonunions in Germany – a descriptive report	6
Osteocyte-specific dentin matrix protein 1	6
Identification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone	6
Autologous meniscus fragments embedded in atelocollagen gel enhance meniscus repair in a rabbit model	6
The role of intermittent PTH administration in conjunction with allogenic stem cell treatment to stimulate fracture healing	6
Global and local fat effects on bone mass and quality in obesity	6
Knee immobilization reproduces key arthrofibrotic phenotypes in mice	6
3D printing in orthopaedic surgery: a scoping review of randomized controlled trials	6
Repetitive combined doses of bacteriophages and gentamicin protect against Staphylococcus aureus implant-related infections in Galleria mellonella	6
Computational analysis of tibial slope adjustment with fixed-bearing medial unicompartmental knee arthroplasty in ACL- and PCL-deficient models	6
Sheep condyle model evaluation of bone marrow cell concentrate combined with a scaffold for repair of large osteochondral defects	6
A mixed-methods approach exploring acceptability and feasibility of trials designed to test drugs targeting prevention of post-traumatic osteoarthritis after knee injury	6
Infographic: Total hip arthroplasty in early osteoarthritis	6
Metal ion toxicity	6
CircStrn3 targeting microRNA-9-5p is involved in the regulation of cartilage degeneration and subchondral bone remodelling in osteoarthritis	5
Predicting whether patients will achieve minimal clinically important differences following hip or knee arthroplasty	5
Septic arthritis in an in vivo murine model induced by Staphylococcus aureus	5
The IMPACT of COVID-19 on trauma & orthopaedic surgery provides lessons for future communicable disease outbreaks	5
Retraction notice	5
Transcutaneous osseointegration for amputees	5
Factors associated with Achilles tendon re-rupture following operative fixation	5
Suramin enhances chondrogenic properties by regulating the p67phox/PI3K/AKT/SOX9 signalling pathway	5
Transcriptomic analyses and machine-learning methods reveal dysregulated key genes and potential pathogenesis in human osteoarthritic cartilage	5
Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis	5
The in vivo location of edge-wear in hip arthroplasties	5
Periprosthetic joint infections: navigating innovations and potential translation	5
Treatment of infected bone defects with the induced membrane technique	5
Effect of stem position and length on bone-stem constructs after cementless hip arthroplasty	5
Vibratory insertion of press-fit acetabular components requires less force than a single blow technique	5
Preoperative measures of bone mineral density from digital wrist radiographs	5
Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway	5
Halicin remains active against Staphylococcus aureus in biofilms grown on orthopaedically relevant substrates	5
Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress	5
Prediction of implant failure risk due to periprosthetic femoral fracture after primary elective total hip arthroplasty	5
Prioritization versus rationing of healthcare – elective surgery is not optional surgery	5
Multidimensional characteristics are associated with pain severity in osteonecrosis of the femoral head	5
Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors	5
Are we doing the right surgical trials?	4
The CREB1 inhibitor 666-15 maintains cartilage homeostasis and mitigates osteoarthritis progression	4
Cytokines and regulatory T cells in ankylosing spondylitis	4
Volume and location of bone regeneration after autologous expanded mesenchymal stromal cells in hip osteonecrosis	4
Terminology of bone and joint infection	4
Finite element analysis safety of tibial cortex transverse transport	4
Increased local bone turnover in patients with chronic periprosthetic joint infection	4

Osteochondral lesions of talus	4
Signalling and putative therapeutic molecules on the regulation of synoviocyte signalling in rheumatoid arthritis	4
A bilayer scaffold of collagen and nanohydroxyapatite promotes osteochondral defect repair in rabbit knee joints	4
Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway	4
Inflammatory bowel disease is associated with an increased risk of adverse events in patients undergoing joint arthroplasty	4
The role of cells and signal pathways in subchondral bone in osteoarthritis	4
Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection	4
The role of TGF-β2 in cartilage development and diseases	4
Corrigenda	4
Human osteoblasts obtained from distinct periarticular sites demonstrate differences in biological function in vitro	4
Comprehensive analysis of pathological changes in hip joint capsule of patients with developmental dysplasia of the hip	4
Application of loaded graphene oxide biomaterials in the repair and treatment of bone defects	4
Diagnosis of periprosthetic joint infections in patients who have rheumatoid arthritis	4
Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty	4
A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis	4
Future registry research	3
Synovial vancomycin and meropenem concentrations in periprosthetic joint infection treated by single-stage revision combined with intra-articular infusion	3
Elution of rifampin and vancomycin from a weight-bearing silorane-based bone cement	3
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin	3
The core outcomes for open lower limb fracture study	3
Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency through pathways instated by increased expression of klotho	3
Thickness of simple calcaneal tuberosity avulsion fractures influences the optimal fixation method employed	3
Adenosine, lidocaine, and magnesium therapy augments joint tissue healing following experimental anterior cruciate ligament rupture and reconstruction	3
Orthopaedic long COVID - the unknown unknowns	3
Exercise modifies the disease-relevant gut microbial shifts in post-traumatic osteoarthritis rats	3
Detection of rare microorganisms in bone and joint infections by metagenomic next-generation sequencing	3
Low incidence of acute kidney injury with combined intravenous and topical antibiotic infusions in periprosthetic joint infection after total knee arthroplasty	3
The reconstruction of critical bone loss	3
Effect of secretory leucocyte protease inhibitor on early tendon-to-bone healing after anterior cruciate ligament reconstruction in a rat model	3
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice	3
Transcriptome-wide association study identifies new susceptibility genes for degenerative cervical spondylosis	3
PARP-1 inhibition attenuates the inflammatory response in the cartilage of a rat model of osteoarthritis	3
The role of Staphylococcus aureus small colony variants in intraosseous invasion and colonization in periprosthetic joint infection	3
Intra-articular low-dose parathyroid hormone (1-34) improves mobility and articular cartilage quality in a preclinical age-related knee osteoarthritis model	3
Development and validation of a gene signature predicting the risk of postmenopausal osteoporosis	3