Bone & Joint Research

Article	Citations
Long-term patient-related quality of life after fracture-related infections of the long bones	45
Robotic arm-assisted versus manual total hip arthroplasty	44
The role of gut microbiota in bone homeostasis	40
Diagnosing periprosthetic joint infections	38
The prevalence, mortality, and associated risk factors for developing COVID-19 in hip fracture patients: a systematic review and meta-analysis	37
Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty	33
The role of TGF-β2 in cartilage development and diseases	32
Patient-reported outcome measures used in patients undergoing total knee arthroplasty	31
3D printing in orthopaedic surgery: a scoping review of randomized controlled trials	29
Immunomodulatory role of T helper cells in rheumatoid arthritis	28
Artificial intelligence in orthopaedic surgery	28
Shared genetic liability between major depressive disorder and osteoarthritis	27
The incidence of musculoskeletal injuries: a systematic review and meta-analysis	27
Fracture-related infection	26
Role of microRNA in muscle regeneration and diseases related to muscle dysfunction in atrophy, cachexia, osteoporosis, and osteoarthritis	26
microRNA-136-5p from bone marrow mesenchymal stem cell-derived exosomes facilitates fracture healing by targeting LRP4 to activate the Wnt/β-catenin pathway	26
The function of lncRNAs in the pathogenesis of osteoarthritis	25
Efficacy and safety of intrawound vancomycin in primary hip and knee arthroplasty	25
Intra-articular injection of human umbilical cord mesenchymal stem cells ameliorates monosodium iodoacetate-induced osteoarthritis in rats by inhibiting cartilage degradation and inflammation	25
Tendon healing: a concise review on cellular and molecular mechanisms with a particular focus on the Achilles tendon	24
Tibial cortex transverse transport accelerates wound healing via enhanced angiogenesis and immunomodulation	24
Hsa_circ_0066523 promotes the proliferation and osteogenic differentiation of bone mesenchymal stem cells by repressing PTEN	23
Mechanical effects of surgical variations in the femoral neck system on Pauwels type III femoral neck fracture	23
Terminology of bone and joint infection	23
LY3023414 inhibits both osteogenesis and osteoclastogenesis through the PI3K/Akt/GSK3 signalling pathway	21

Robotic-arm assisted THA can achieve precise cup positioning in developmental dysplasia of the hip	21
Diagnostic accuracy of neutrophil counts in histopathological tissue analysis in periprosthetic joint infection using the ICM, IDSA, and EBJIS criteria	21
Effects of different tissue specimen pretreatment methods on microbial culture results in the diagnosis of periprosthetic joint infection	21
Extracellular vesicles derived from mesenchymal stem cells containing microRNA-381 protect against spinal cord injury in a rat model via the BRD4/WNT5A axis	20
Advanced oxidation protein products induce inflammatory responses and invasive behaviour in fibroblast-like synoviocytes via the RAGE-NF-κB pathway	20
Current status of regenerative medicine in osteoarthritis	19
Effect of stem position and length on bone-stem constructs after cementless hip arthroplasty	19
ATF3 as a potential diagnostic marker of early-stage osteoarthritis and its correlation with immune infiltration through bioinformatics analysis	19
Fibrinolysis as a target to enhance osteoporotic fracture healing by vibration therapy in a metaphyseal fracture model	18
CircSCAPER contributes to IL-1β-induced osteoarthritis in vitro via miR-140-3p/EZH2 axis	17
Clinical outcomes following intra-articular injection of autologous adipose-derived mesenchymal stem cells for the treatment of osteoarthritis in dogs characterized by weight-bearing asymmetry	17
Osseointegration of retrieved 3D-printed, off-the-shelf acetabular implants	17
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway	17
Tert-butylhydroquinone attenuates osteoarthritis by protecting chondrocytes and inhibiting macrophage polarization	17
Periprosthetic joint infection	17
Focal osteolysis and corrosion at the junction of Precice Stryde intramedullary lengthening device	17
Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis	17
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	16
Gut microbiota is associated with bone mineral density	16
Biomechanical comparison of medial sustainable nail and proximal femoral nail antirotation in the treatment of an unstable intertrochanteric fracture	16
The role of multidisciplinary teams in musculoskeletal infection	15
Long noncoding RNA H19 alleviates inflammation in osteoarthritis through interactions between TP53, IL-38, and IL-36 receptor	15
Comparison of cell therapy and other novel adjunctive therapies combined with core decompression for the treatment of osteonecrosis of the femoral head	15
Meaningful values in the Short Form Health Survey-36 after total knee arthroplasty – an alternative to the EuroQol five-dimension index as a measure for health-related quality of life	15
Exposure to hypergravity during zebrafish development alters cartilage material properties and strain distribution	15
Clinical evaluation after matrix-associated autologous chondrocyte transplantation	15
3D-printed titanium implant combined with interleukin 4 regulates ordered macrophage polarization to promote bone regeneration and angiogenesis	14
Outcomes following surgical management of femoroacetabular impingement: a systematic review and meta-analysis of different surgical techniques	14
A novel antimicrobial coating to prevent periprosthetic joint infection	14
Proximal humerus fractures – epidemiology, comparison of mortality rates after surgical versus non-surgical treatment, and analysis of risk factors based on Medicare registry data	14
Antibiofilm efficacy of focused high-energy extracorporeal shockwaves and antibiotics in vitro	14
Do E-cigarettes and vaping have a lower risk of osteoporosis, nonunion, and infection than tobacco smoking?	13
Predicting whether patients will achieve minimal clinically important differences following hip or knee arthroplasty	13
Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density	13
Intra-articular low-dose parathyroid hormone (1-34) improves mobility and articular cartilage quality in a preclinical age-related knee osteoarthritis model	13
Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis	13
Fracture-related infection in osteoporotic bone causes more severe infection and further delays healing	13
A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis	13
MicroRNA-183attenuates osteoarthritic pain by inhibiting theTGFα-mediatedCCL2/CCR2signalling axis	13
Exercise modifies the disease-relevant gut microbial shifts in post-traumatic osteoarthritis rats	12
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	12
Management of surgical site infection post-open reduction and internal fixation for tibial plateau fractures	12
Cytokines and regulatory T cells in ankylosing spondylitis	12
Osteoblast function in patients with idiopathic osteonecrosis of the femoral head	12
Do preoperative intra-articular injections of corticosteroids or hyaluronic acid increase the risk of infection after total knee arthroplasty? A meta-analysis	12
Signalling and putative therapeutic molecules on the regulation of synoviocyte signalling in rheumatoid arthritis	12
Systemic administration with melatonin in the daytime has a better effect on promoting osseointegration of titanium rods in ovariectomized rats	11
Orthopaedic long COVID - the unknown unknowns	11
Diabetes – osteoarthritis and joint pain	11
Current therapeutic interventions combating biofilm-related infections in orthopaedics	11

GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis	11
The role of Staphylococcus aureus small colony variants in intraosseous invasion and colonization in periprosthetic joint infection	11
Can barb thread design improve the pullout strength of bone screws?	11
The extensor efficiency of unicompartmental, bicompartmental, and total knee arthroplasty	10
Development of a large animal rabbit model for chronic periprosthetic joint infection	10
The reconstruction of critical bone loss	10
Effects of focused continuous pulsed electromagnetic field therapy on early tendon-to-bone healing	10
Effectiveness of mechanical cleaning, antibiotics, and induction heating on eradication of Staphylococcus aureus in mature biofilms	10
PARP-1 inhibition attenuates the inflammatory response in the cartilage of a rat model of osteoarthritis	10
Cobalt-induced cardiomyopathy – do circulating cobalt levels matter?	10
The effectiveness of platelet-rich plasma gel on full-thickness cartilage defect repair in a rabbit model	10
Radiological and clinical outcomes using induced membrane technique combined with bone marrow concentrate in the treatment of chronic osteomyelitis of immature patients	9
Flucloxacillin bone and soft tissue concentrations assessed by microdialysis in pigs after intravenous and oral administration	9
Rejuvenated ageing mesenchymal stem cells by stepwise preconditioning ameliorates surgery-induced osteoarthritis in rabbits	9
N,N-Dimethylformamide inhibits high glucose-induced osteoporosis via attenuating MAPK and NF-κB signalling	9
Intra-articular celecoxib improves knee extension regardless of surgical release in a rabbit model of arthrofibrosis	9
The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis	9
Transcutaneous osseointegration for amputees	9
Osteoimmunology and osteonecrosis of the femoral head	9
Comparison of periprosthetic femoral fracture torque and strain pattern of three types of femoral components in experimental model	9
Infection after intracapsular femoral neck fracture – does antibiotic-loaded bone cement reduce infection risk after hemiarthroplasty and total hip arthroplasty?	8
Elution of rifampin and vancomycin from a weight-bearing silorane-based bone cement	8
CircStrn3 targeting microRNA-9-5p is involved in the regulation of cartilage degeneration and subchondral bone remodelling in osteoarthritis	8
Cortical bone thickness of the distal radius predicts the local bone mineral density	8
The effect of cement augmentation on pedicle screw fixation under various load cases	8
TGF-β1 derived from macrophages contributes to load-induced tendon-bone healing in the murine rotator cuff repair model by promoting chondrogenesis	8
Capsular ligaments provide a passive stabilizing force to protect the hip against edge loading	8
Negative pressure wound therapy does not diminish efficacy of topical antibiotic powder in a preclinical contaminated wound model	8
Prioritization versus rationing of healthcare – elective surgery is not optional surgery	8
Comprehensive analysis of pathological changes in hip joint capsule of patients with developmental dysplasia of the hip	8
Anti-tumour effect of tocilizumab for osteosarcoma cell lines	8
Hip preservation surgery and the acetabular fossa	8
Synovial fluid neutrophil extracellular traps could improve the diagnosis of periprosthetic joint infection	8
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope	8
Application of 68Ga-citrate PET/CT for differentiating periprosthetic joint infection from aseptic loosening after joint replacement surgery	8
The IMPACT of COVID-19 on trauma & orthopaedic surgery provides lessons for future communicable disease outbreaks	8
MicroRNA-486 promotes a more catabolic phenotype in chondrocyte-like cells by targeting SIRT6	8
Impact of racial disparities and insurance status in patients with bone sarcomas in the USA	8
Does tibial design modification improve implant stability for total knee arthroplasty? An experimental cadaver study	8
Dead muscle tissue promotes dystrophic calcification by lowering circulating TGF-β1 level	7
Sheep condyle model evaluation of bone marrow cell concentrate combined with a scaffold for repair of large osteochondral defects	7
Alcohol-induced inhibition of bone formation and neovascularization contributes to the failure of fracture healing via the miR-19a-3p/FOXF2 axis	7
Roentgen stereophotogrammetric analysis: still a very valuable tool in the orthopaedic research armamentarium	7
Evaluation of at-home physiotherapy	7
Bi-unicondylar arthroplasty	7
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways	7
The association between selenium and bone health: a meta-analysis	7
Effect of resistance training on satellite cells in old mice – a transcriptome study	7
Sonographic bridging callus at six weeks following displaced midshaft clavicle fracture can accurately predict healing	7
What is the appropriate extended duration of antibiotic prophylaxis after two-stage revision for chronic PJI?	7
Rifampicin restores extracellular organic matrix formation and mineralization of osteoblasts after intracellular Staphylococcus aureus infection	6
Predicted waiting times for orthopaedic surgery	6
Effect of carbazochrome sodium sulfonate combined with tranexamic acid on blood loss and inflammatory response in patients undergoing total hip arthroplasty	6
The epidemiology and direct healthcare costs of aseptic nonunions in Germany – a descriptive report	6
The role of intermittent PTH administration in conjunction with allogenic stem cell treatment to stimulate fracture healing	6
Antimicrobial rationing in orthopaedic surgery	6
BRD4promotes heterotopic ossification through upregulation of LncRNA MANCR	6
Auraptene ameliorates osteoporosis by inhibiting RANKL/NFATc1 pathway-mediated bone resorption based on network pharmacology and experimental evaluation	6
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages	6
Augmentation of implant surfaces with BMP-2 in a revision setting	6
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin	6
Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress	6
The metabolic equivalent of task score	6
The effect of TNF-α on osteoblasts in metal wear-induced periprosthetic bone loss	6
The effect induced by alternated mechanical loading on Notch-1 in mandibular condylar cartilage of growing rabbits	6
A large-scale genetic correlation scan between rheumatoid arthritis and human plasma protein	6
Differences between infected and noninfected synovial fluid	6
The role of cells and signal pathways in subchondral bone in osteoarthritis	6
Preoperative measures of bone mineral density from digital wrist radiographs	6
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	6
Ultrasound-targeted simvastatin-loaded microbubble destruction promotes OA cartilage repair by modulating the cholesterol efflux pathway mediated by PPARγ in rabbits	6
Biomechanical effect of anatomical tibial component design on load distribution of medial proximal tibial bone in total knee arthroplasty	5
Animal experimental investigation on the efficacy of antibiotic therapy with linezolid, vancomycin, cotrimoxazole, and rifampin in treatment of periprosthetic knee joint infections by MRSA	5
Development and validation of a gene signature predicting the risk of postmenopausal osteoporosis	5
Identification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone	5
The role of accelerated growth plate fusion in the absence of SOCS2 on osteoarthritis vulnerability	5
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary hip arthroplasty in England and Wales	5
Validation of joint space narrowing on plain radiographs and its relevance to partial knee arthroplasty	5
GNAQ knockdown promotes bone metastasis through epithelial-mesenchymal transition in lung cancer cells	5
Human osteoblasts obtained from distinct periarticular sites demonstrate differences in biological function in vitro	5

Radiodynamic therapy with acridine orange local administration as a new treatment option for primary and secondary bone tumours	5
Intermittent parathyroid hormone increases stability and improves osseointegration of initially unstable implants	5
Influence of ceftriaxone on human bone cell viability and in vitro mineralization potential is concentration- and time-dependent	5
Subchondral physiology and vasculo-mechanical factors in load transmission and osteoarthritis	5
Total and partial knee arthroplasty implants that maintain native load transfer in the tibia	5
Suramin enhances chondrogenic properties by regulating the p67phox/PI3K/AKT/SOX9 signalling pathway	5
Peripheral nerves in the tibial subchondral bone	5
Comparison of ligamentization potential between anterior cruciate ligament-derived cells and adipose-derived mesenchymal stem cells reseeded to acellularized tendon allograft	5
Effect of the additional anteroposterior blocking screw on nail/medullary canal mismatch after cephalomedullary nailing in unstable pertrochanteric fracture	4
The accuracy of restoration of femoral head centre of rotation in the anteroposterior plane after uncemented total hip arthroplasty	4
Artificial intelligence in orthopaedics	4
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	4
Monomeric CRP regulates inflammatory responses in human intervertebral disc cells	4
Personalized estimation of one-year mortality risk after elective hip or knee arthroplasty for osteoarthritis	4
What outcomes have been reported on patients following open lower limb fracture, and how have they been measured?	4
Effect of secretory leucocyte protease inhibitor on early tendon-to-bone healing after anterior cruciate ligament reconstruction in a rat model	4
Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors	4
Treatment of infected bone defects with the induced membrane technique	4
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	4
Intra-articular versus systemic vancomycin for the treatment of periprosthetic joint infection after debridement and spacer implantation in a rat model	4
Should concurrent viral (including COVID-19) or bacterial infections be treated before performing surgery for hip fracture?	4
Bone turnover markers as surrogates of fracture healing after intramedullary fixation of tibia and femur fractures	4
Importance of posterior tibial slope in joint kinematics with an anterior cruciate ligament-deficient knee	4
Human acellular amniotic membrane scaffolds encapsulating juvenile cartilage fragments accelerate the repair of rabbit osteochondral defects	4
Histone deacetylase inhibitors attenuated interleukin-1β-induced chondrogenesis inhibition in synovium-derived mesenchymal stem cells of the temporomandibular joint	4
LncRNA PCBP1-AS1 induces osteoporosis by sponging miR-126-5p/PAK2 axis	4
The delivery of an emergency audit response to a communicable disease outbreak can inform future orthopaedic investigations and clinical practice	4
Three orthopaedic operations, over 1,000 randomized controlled trials, in over 100,000 patients	4
Real time measurement of intramuscular pH during routine knee arthroscopy using a tourniquet	4
Tibial bone and soft-tissue concentrations following combination therapy with vancomycin and meropenem – evaluated by microdialysis in a porcine model	4
Development of a core outcome set for open lower limb fracture	4
Synovial fluid peptidase activity as a biomarker for knee osteoarthritis clinical progression	4
Volume and location of bone regeneration after autologous expanded mesenchymal stromal cells in hip osteonecrosis	4
Autologous meniscus fragments embedded in atelocollagen gel enhance meniscus repair in a rabbit model	4