Bone & Joint Research

Article	Citations
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	170
Prognostic factors associated with failure of total elbow arthroplasty	94
Enhancing precision in limb-salvage surgery	92
Candy box technique with sutures and Nice knot	91
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	74
Ultrasound combined with voriconazole for treating acute fungal periprosthetic joint infection caused by Candida albicans	56
Ontogenetic changes in femoral morphology and joint loads in children	53
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	49
The effect of impaction energy and bone quality on cementless femoral implant fixation and femoral periprosthetic fracture risk	47
The future of osteoarthritis treatment: exploring the potential of exosomes from adipose tissue-derived stem cells	36
Mental health implications of fracture-related infections	34
Feasibility and reliability of shear wave elastography-guided collateral ligament balancing during total knee arthroplasty	32
Can severity of trunnion damage be estimated by visual inspection alone?	32
Managing large type 2a bone defects from osteoporotic tibial plateau fractures	32
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	30
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	30
Subluxation-induced liner adhesion and the effect of impaction to prevent liner dislocation in ceramic hip arthroplasty	29
CDK12 mediates the inhibition effect of mechanical unloading on osteoblast proliferation by regulating RNAPII transcription activation	29
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	27
Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	27
Diagnosing periprosthetic joint infections	26
Discogenic pain in lumbar vertebra	25
Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis	25
Osteochondral lesions of talus	25
Therapeutic potential of IκB kinase epsilon inhibition in preventing meniscal degeneration of early osteoarthritis	24

Reviewer acknowledgement	24
Prediction of implant failure risk due to periprosthetic femoral fracture after primary elective total hip arthroplasty	24
FGF9 attenuates osteoarthritis progression through the NRF2/GPX3 antioxidant axis	23
Application of loaded graphene oxide biomaterials in the repair and treatment of bone defects	22
The CREB1 inhibitor 666-15 maintains cartilage homeostasis and mitigates osteoarthritis progression	22
Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway	21
Beyond the surface: anterior cruciate ligament assessment in knee osteoarthritis	21
Finite element analysis safety of tibial cortex transverse transport	21
The role of cells and signal pathways in subchondral bone in osteoarthritis	21
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats	20
Navigating change: upholding scientific integrity in an era of innovation	20
Future registry research	19
High-resolution peripheral quantitative CT of the proximal fifth metatarsal reveals microstructural similarity between Lawrence and Botte zones I and II	19
A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis	18
Transcriptome-wide association study identifies new susceptibility genes for degenerative cervical spondylosis	18
Oxygen tension alters cartilage redox balance in response to traumatic impact	18
Hederagenin promotes SIRT6 to attenuate epidural scar formation by aggravating PRMT1 deacetylation	18
Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27kip1 pathway	18
High-intensity running exercise promotes knee meniscal damage via the PI3K/AKT/mTOR axis	17
Functionalizing biomaterials for osseointegration – microRNAs at the crossroads of bone formation and immune modulation	17
Detection of rare microorganisms in bone and joint infections by metagenomic next-generation sequencing	17
Detection limitations of bacteria in tissue samples	17
An analysis of the medial femoral condyle flap anatomy and the involvement of different tissue components for the reconstruction of complex defects	16
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages	16
Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing	16
Biomechanical study of screw-supported prosthesis in acetabular revision	16
CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro	16
Diathermy and bone sawing are high aerosol yield procedures	15
Longitudinal monitoring of bone remodelling activity around the acetabular cup after total hip arthroplasty using 18F-fluoride PET/CT scans	15
Current therapeutic interventions combating biofilm-related infections in orthopaedics	15
siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc dege	14
Proximal humerus fractures – epidemiology, comparison of mortality rates after surgical versus non-surgical treatment, and analysis of risk factors based on Medicare registry data	14
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope	14
Induction heating combined with antibiotics or SAAP-148 effectively reduces biofilm-embedded Staphylococcus aureus on a fracture-related implant mimic	14
Identification of age-related genes in rotator cuff tendon	14
More severe joint disease and lower patient oxygenation are associated with less corrosive in vivo synovial fluid in patients with knee osteoarthritis	13
Overcoming barriers to interdisciplinary research in engineering and orthopaedic surgery	13
Panoramic heat map for spatial distribution of necrotic lesions	13
Reviewer acknowledgement	13
The diagnostic accuracy of serum and synovial inflammatory markers in chronic periprosthetic joint infection among anaemic patients	13
Preoperative prediction for periprosthetic bone loss and individual evaluation of bisphosphonate effect after total hip arthroplasty using artificial intelligence	12
HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice	12
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary hip arthroplasty in England and Wales	12
Cystic lesions in osteoarthritis and osteonecrosis of the femoral head	12
Clinical study on the 3D morphology and mechanical factors of lumbar facet joints in patients with degenerative lumbar spondylolisthesis	12
The role of AGEs in muscle ageing and sarcopenia	12
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	11
Impact of tranexamic acid on the efficacy of vancomycin and meropenem against periprosthetic joint infections	11
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	11
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	11

Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	11
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	11
Corrigendum	11
Three decades of transformation: a bibliometric study of gender and geographic trends in international orthopaedic journal publications	11
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	11
Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	10
Impact of elevated sclerostin levels on bone resorption	10
Vascular remodelling and fibrotic changes in the joint capsule during periprosthetic knee infections	10
Corrigendum	10
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	10
Patellar luxation causes abnormal mechanical loading and joint destruction in the femoral-tibial joint	10
Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review	10
Factors associated with Achilles tendon re-rupture following operative fixation	9
Persistent bone and muscle deficits after anterior cruciate ligament reconstruction	9
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin	9
Effect of human adipose stem cell-derived mitochondrial transplantation on the activity of chronically injured anterior cruciate ligament cells	9
Femoral impingement in maximal hip flexion is anterior-inferior distal to the cam deformity in femoroacetabular impingement patients with femoral retroversion	9
Anatomy changes, signalling pathways, and clinical treatment after ankle sprain	9
Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress	9
Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection	9
Increased local bone turnover in patients with chronic periprosthetic joint infection	9
Type-I and -II collagens from bone and cartilage colocalize at the osteochondral cement line	9
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	9
Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency through pathways instated by increased expression of klotho	9
Single-cell transcriptomics analysis of the healing process of ligament rupture	9
Antiosteoporotic treatment promotes tendon-to-bone healing after rotator cuff repair	9
Achieved discharge outcome targets in patient-reported outcome measures after lower limb arthroplasty	8
Finite element analysis, biomechanics, and clinical advantages of percutaneous medial column screw reinforced locking plate in the treatment of complex distal femoral fractures	8
Importance of posterior tibial slope in joint kinematics with an anterior cruciate ligament-deficient knee	8
The evaluation of osteoconductive WE43 magnesium as a therapeutic approach for nonunion treatment	8
Basic research for ultrasound-guided injection into skeletal muscle lesions in an experimental animal model	8
Accelerometer-measured postoperative physical activity confers a significant mortality benefit following joint arthroplasty	8
Evaluating upper leg muscle volume	8
Evaluation of the causal relationship between 28 circulating biomarkers and osteoarthritis	8
The role of neutrophils in the pathophysiology of knee osteoarthritis	8
The role of Staphylococcus aureus small colony variants in intraosseous invasion and colonization in periprosthetic joint infection	8
Adenosine, lidocaine, and magnesium therapy augments joint tissue healing following experimental anterior cruciate ligament rupture and reconstruction	8
Biomechanical comparison between custom-made enhanced triflange and quadri-flange acetabular components for the treatment of Paprosky IIIB acetabular bone defects	8
Effectiveness of mechanical cleaning, antibiotics, and induction heating on eradication of Staphylococcus aureus in mature biofilms	8
Qualitative methods: the missing link in orthopaedic research	7
Long-term hypoxic atmosphere enhances the stemness, immunoregulatory functions, and therapeutic application of human umbilical cord mesenchymal stem cells	7
The impact of cementing technique in polished taper fit hip stems	7
Biomimetic tri-layered osteochondral scaffold	7
Increased loading of the lateral knee compartment in the unamputated knee during gait in people with unilateral transfemoral/through-knee amputations	7
The degenerated glenohumeral joint	7
Efficacy of a saline wash plus vancomycin/tobramycin-doped PVA composite (PVA-VAN/TOB-P) in a mouse pouch infection model implanted with 3D-printed porous titanium cylinders	7
Effects of high antibiotic concentrations applied to continuous local antibiotic perfusion on human bone tissue-derived cells	7
Overcoming the detrimental impact of volumetric muscle loss on segmental fracture healing via the induced membrane technique	7
PEDF peptide plus hyaluronic acid stimulates cartilage regeneration in osteoarthritis via STAT3-mediated chondrogenesis	7
Growth differentiation factor 15 as a potential diagnostic biomarker for rheumatoid arthritis	7
Lateral unicompartmental knee arthroplasty is associated with nearer-normal gait characteristics and higher patient satisfaction compared to total knee arthroplasty	7
Infographic: Chongqing technique	7
TGF-β1 derived from macrophages contributes to load-induced tendon-bone healing in the murine rotator cuff repair model by promoting chondrogenesis	7
Identification of the molecular link: STAT3 is a shared key gene linking postmenopausal osteoporosis and sarcopenia	7
Clinical, oncological, and prognostic differences of patients with subsequent skeletal-related events in bone metastases	7
Development and validation of a novel prediction model for osteoporosis	7
Transcutaneous carbon dioxide improves joint inflammation and articular cartilage degeneration in rat osteoarthritis models	7
Reviewer acknowledgement	7
Prospective clinical trial analyzing serum mast cell tryptase levels and arthrofibrosis rates after total knee arthroplasty	6
LncRNA PCBP1-AS1 induces osteoporosis by sponging miR-126-5p/PAK2 axis	6
An immunoregenerative approach to mitigate post-traumatic osteoarthritis after intra-articular fracture	6
Finite element study of the role of medial longitudinal arch in hallux valgus deformity	6
Damage control orthopaedics is associated with impaired fracture healing and delayed recovery in a rodent model of severe multiple trauma	6
The interactions of macrophages, lymphocytes, and mesenchymal stem cells during bone regeneration	6
The transcriptional atlas, intercellular communication, and metabolic reprogramming of the cartilage and synovium in osteoarthritis patients with diabetes mellitus	6
Development of a new treatment for osteoporotic vertebral fractures using adipose-derived stem cell spheroids	6
Complex network model reveals the positive effect of melatonin on bone parameters in rats with induced hypoestrogenism	6
Retraction notice	6
A bilayer scaffold of collagen and nanohydroxyapatite promotes osteochondral defect repair in rabbit knee joints	6
Stable polyethylene inlay fixation and low polyethylene wear rate in fixed-bearing total knee arthroplasty at five to six years’ follow-up	6
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways	6
Comparison of the mechanical performance of intramedullary nail and locking plate in tibiotalocalcaneal arthrodesis	6
Astragalus polysaccharide promotes osteogenic differentiation of human bone marrow derived mesenchymal stem cells by facilitating ANKFY1 expression through miR-760 inhibition	6
Ergothioneine prevents ovariectomy-induced osteoporosis by suppressing NF-κB/p65 signalling to attenuate osteoclastogenesis and bone marrow inflammation	6
Infographic: Total hip arthroplasty in early osteoarthritis	6
Genotype and phenotype correlation analysis in 27 families with multiple osteochondroma and validation by ATDC5 chondrocyte models	6
Meniscus cell lysate induces mitochondrial dysfunction of fibroblast-like synoviocytes via upregulating ANT3 in osteoarthritis	6
Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis	6
Volume and location of bone regeneration after autologous expanded mesenchymal stromal cells in hip osteonecrosis	5
Are we doing the right surgical trials?	5

Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors	5
Predicted waiting times for orthopaedic surgery	5
Rapid multiplex micro-ELISA assay for simultaneous measurement of synovial biomarkers	5
Multiple roles of ALK3 in osteoarthritis	5
Repetitive combined doses of bacteriophages and gentamicin protect against Staphylococcus aureus implant-related infections in Galleria mellonella	5
Cry2 prompts clock oscillation and temporomandibular joint homeostasis under mechanical loading	5
Changes in the shape of the lumbar curve during growth	5
Autologous osteoperiosteal graft shows superior outcomes to bone graft in shelf acetabuloplasty for acetabular dysplasia	5
Repurposing the diuretic benzamil as an anti-osteosarcoma agent that acts by suppressing integrin/FAK/STAT3 signalling and compromising mitochondrial function	5
Arthroscopic cam resection reduces femoroacetabular contact pressure	5
Cytokines and regulatory T cells in ankylosing spondylitis	5
Regeneration of injured articular cartilage using the recombinant human amelogenin protein	5
MRI-based radiomics explainable model for predicting recurrence of limb chronic osteomyelitis in limb bones treated by Masquelet technique	5
Phenotypic divergence in rotator cuff tear and volumetric muscle loss mouse models following fibroadipogenic progenitor depletion	5
Aberrant anabolism hinders constructive metabolism of chondrocytes by pharmacotherapy in osteoarthritis	5
Appraising causal risk and protective factors for rheumatoid arthritis	5
Expression of Concern	4
Knee kinematics during staircase descent	4
Concomitant osteochondral lesion of the talus affects in vivo ankle kinetics in patients with chronic ankle instability	4
In vivo reduction of biofilm seeded on orthopaedic implants	4
Biomechanical evaluation of asymmetric metaphyseal cone applications for lateral tibial plateau fractures	4
Development and validation of an open-source tool for opportunistic screening of osteoporosis from hip CT images	4
Wound fluid ceftriaxone concentrations after local application with calcium sulphate as carrier material in the treatment of orthopaedic device-associated hip infections	4
Upregulated ribosome pathway plays a key role in HDAC4, improving the survival rate and biofunction of chondrocytes	4
Clinical efficacy and safety of P-15 peptide enhanced bone graft substitute in surgical bone regenerative procedures in adult maxillofacial, spine, and trauma patients	4
Cyclin D1 mediates pain behaviour in a rat model of breast cancer-induced bone pain by a mechanism involving regulation of the proliferation of spinal microglia	4
Monomeric CRP regulates inflammatory responses in human intervertebral disc cells	4
The Clinical Practice Integration of Artificial Intelligence (CPI-AI) framework	4
The role of BioFire Joint Infection Panel in diagnosing periprosthetic hip and knee joint infections in patients with unclear conventional microbiological results	4
Quantitative evaluation of cervical muscles in patients with degenerative cervical myelopathy using diffusion tensor imaging metrics	4
Effect of treadmill training on fibrocartilage complex repair in tendon-bone insertion healing in the postinflammatory stage	4
The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development	4
Enhancement of hyaline cartilage and subchondral bone regeneration in a rat osteochondral defect model through focused extracorporeal shockwave therapy	4
Tendon healing: a concise review on cellular and molecular mechanisms with a particular focus on the Achilles tendon	4
Abnormal mechanical stress due to excessive femoral torsion is associated with dysplasia of the distal femoral epiphyseal plate and trochlea	4
Melatonin induces RAW264.7 cell apoptosis via the BMAL1/ROS/MAPK-p38 pathway to improve postmenopausal osteoporosis	4