OOIR: Observatory of International Research

Papers

(The TQCC of Open Biology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Oxidized phospholipid damage signals as modulators of immunity	166
Autophagy: a novel target in order to overcome drug resistance in pancreatic adenocarcinoma	114
A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis	79
Retraction: ‘HOXD-AS1 confers cisplatin resistance in gastric cancer through epigenetically silencing PDCD4 via recruiting EZH2’ (2019), by Ye et al.	71
Decoding life's inner workings: advances in quantitative bioimaging	55
Limitations of sequence dissimilarity as a predictor of prokaryotic lineage	50
Into the second decade	47
Correction to: ‘Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae ’ (2024),	44
Visualization of sympathetic neural innervation in human white adipose tissue	43
MYH7 R453C induced cardiac remodelling via activating TGF-β/Smad2/3, ERK1/2 and Nox4/ROS/NF-κB signalling pathways	43
Comparative mitogenomic analysis and phylogeny of Veneridae with doubly uniparental inheritance	43
RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication	42
Nutrient-sensitive protein O-GlcNAcylation shapes daily biological rhythms	39
Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?	38
Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours	38
Integrative analysis of genomic and transcriptomic alterations of AGR2 and AGR3 in cancer	37
Identification and characterization of host miRNAs that target the mouse mammary tumour virus (MMTV) genome	36
SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation	36
Risk factors for severe COVID-19 disease increase SARS-CoV-2 infectivity of endothelial cells and pericytes	36
A new view of axon growth and guidance grounded in the stochastic dynamics of actin networks	35
Retraction: ‘Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial-mesenchymal transition by regulating HIF-1α via miR-138’	35
Every good biologist deserves favour	35
Min oscillations in bacteria as real-time reporter of environmental challenges at the single-cell level	34
NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors	33
Transiently restricting individual amino acids protects Drosophila melanogaster against multiple stressors	33

From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs	33
The first genetic engineered system for ovothiol biosynthesis in diatoms reveals a mitochondrial localization for the sulfoxide synthase OvoA	32
Essential roles of the nucleolus during early embryonic development: a regulatory hub for chromatin organization	31
Complement receptor 3-dependent engagement by Candida glabrata β-glucan modulates dendritic cells to induce regulatory T-cell expansion	30
SID-2 is a conserved extracellular vesicle protein that is not associated with environmental RNAi in parasitic nematodes	29
Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p27	28
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system	28
Pleiotropic effects on proliferation and mineralization of primary human adipose tissue-derived stromal cells induced by simvastatin	28
Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response	27
Footprints in the Sno: investigating the cellular and molecular mechanisms of SNORD116	26
Correction to ‘Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments’ (2022) by Kellom et al .	26
Retraction: ‘Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p’ (2020), by Cui et al.	25
A fast-growing dengue virus mutant reveals a dual role of STING in response to infection	24
Au naturale: use of biologically derived cyclic di-nucleotides for cancer immunotherapy	24
Pck2 association with the plasma membrane and efficient response of the cell integrity pathway require regulation of PI4P homeostasis by exomer	24
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation	24
Freshwater-adapted polychaetes exhibit a complete enzymatic machinery for synthesizing long-chain polyunsaturated fatty acids	23
Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae	23
FLP-15 modulates the amplitude of body-bends during locomotion in Caenorhabditis elegans	23
In vitro reconstitution of substrate S-acylation by the zDHHC family of protein acyltransferases	22
The genetic basis and potential molecular mechanism of yellow-albino northern snakehead (Channa argus)	22
The role of α-sheet structure in amyloidogenesis: characterization and implications	21
Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics	20
Multifunctional roles of Sec13 paralogues in the euglenozoan Trypanosoma brucei	20
Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism	20
Interplay between circadian rhythm, ageing and neurodegenerative disorder	20
Learning-induced remodelling of inhibitory synapses in the motor cortex	19
The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint	19
C-terminal glycosylation of type IX secretion system cargo proteins in Prevotella intermedia with both short and long secretion signals	18
Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation	18
Stepwise order in protein complex assembly: approaches and emerging themes	18
Long-read RNA-sequencing reveals transcript-specific regulation in human-derived cortical neurons	18
A circle of life: platelet and megakaryocyte cytoskeleton dynamics in health and disease	18
Proteomic comparison of the organic matrices from parietal and base plates of the acorn barnacle Amphibalanus amphitrite	18
Polycomb-mediated transgenerational epigenetic inheritance of Drosophila eye colour is independent of small RNAs	18
Transcriptional regulation as a dose-dependent process: insights from transcription factor tuning	17
Light-induced reversible reorganizations in closed Type II reaction centre complexes: physiological roles and physical mechanisms	17
Reversible bacteriophage resistance by shedding the bacterial cell wall	17
miR-155-3p: processing by-product or rising star in immunity and cancer?	16
Genome-wide identification of ATP-binding cassette transporter B subfamily, focusing on its structure, evolution and rearrangement in ciliates	16
Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria	16
A distinct phase of cyclin B (Cdc13) nuclear export at mitotic entry in Schizosaccharomyces pombe	15
The supernumerary B chromosome of maize: drive and genomic conflict	15
Whole organism and tissue-specific analysis of pexophagy in Drosophila	15
Temperature activated transient receptor potential ion channels from Antarctic fishes	15
GNL3 is an evolutionarily conserved stem cell gene influencing cell proliferation, animal growth and regeneration in the hydrozoan Hydractinia	15
Expression of concern: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui Y et al.	15
Neuronal signalling of zinc: from detection and modulation to function	15
Prenatal alcohol exposure dysregulates the expression of clock genes and alters rhythmic behaviour in mice	15
Aurodox inhibits type III secretion in multiple Gram-negative pathogens	15

Identification of the modulatory Ca ²⁺ -binding sites of acid-sensing ion channel 1a	14
Effective training of nanopore callers for epigenetic marks with limited labelled data	14
Retraction: ‘Long non-coding RNA LINC00467 regulates hepatocellular carcinoma progression by modulating miR-9-5p/PPARA expression’ (2019), by Cai et al.	14
PIEZO1 variant implications for biological understanding and human health	14
Spatial transcriptomes and microbiota reveal immune mechanism that respond to pathogen infection in the posterior intestine ofSebastes schlegelii	14
Terminal regions of a protein are a hotspot for low complexity regions and selection	14
Plant NLR immunity activation and execution: a biochemical perspective	14
Retraction: ‘MALAT1 promotes gastric adenocarcinoma through the MALAT1/miR-181a-5p/AKT3 axis’ (2019), by Lu et al.	14
Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells	14
The evolutionary entanglement of flipons with zinc fingers and retroelements has engendered a large family of Z-DNA and G-quadruplex binding proteins	13
Unravelling axonal transcriptional landscapes: insights from induced pluripotent stem cell-derived cortical neurons and implications for motor neuron degeneration	13
MicroRNAs: master regulators in host–parasitic protist interactions	13
GLP-1/GLP-1R axis: from metabolism (obesity and T2DM) to immunity	13
Exploring the midgut physiology of the non-haematophagous mosquito Toxorhynchites theobaldi	13
The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex	13
HMGB1 and mitochondrial dysfunction: a double-edged sword in ageing	13
Decoding frontotemporal and cell-type-specific vulnerabilities to neuropsychiatric disorders and psychoactive drugs	13
Pseudogenization of NK3 homeobox 2 ( Nkx3.2 ) in monotremes provides insight into unique gastric anatomy and physiology	12
Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS	12
Polo-like kinase and Aurora B kinase phosphorylate and cooperate with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei	12
Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction	12
PACS deficiency disrupts Golgi architecture and causes cytokinesis failures and seizure-like phenotype in Drosophila melanogaster	12
The challenge of measuring mosquito flight performance: going beyond sterile insect technique and into transgenic and gene drive-based approaches	12
Mapping combinatorial expression of non-clustered protocadherins in the developing brain identifies novel PCDH19-mediated cell adhesion properties	12
Daughter centrioles assemble preferentially towards the nuclear envelope in Drosophila syncytial embryos	12
Transcriptomic and metabolomic insights into light-mediated unicellular-to-multicellular transition in Dictyostelium discoideum	12
Centromere function in asymmetric cell division in Drosophila female and male germline stem cells	12
Exploring differential exon usage via short- and long-read RNA sequencing strategies	12
A simple inland culture system provides insights into ascidian post-embryonic developmental physiology	11
Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m ⁷ G-cap-dependent translation at the 8- to 16-cell transition	11
Insights into the bioluminescence systems of three sea pens (Cnidaria: Anthozoa): from de novo transcriptome analyses to biochemical assays	10
Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades	10
Distinct molecular profile of the chick organizer as a stem zone during axial elongation	10
The proline-rich antimicrobial peptide B7-005: low bacterial resistance, safe for human cells and effective in zebrafish embryo bacteraemia model	10
Capturing crop adaptation to abiotic stress using image-based technologies	10
Discovery of unique mitotic mechanisms in Paradiplonema papillatum	10
Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells	10
Plum modulates Myoglianin and regulates synaptic function in D. melanogaster	10
Lysosomal positioning diseases: beyond substrate storage	10
Expression and function of PDGF-C in development and stem cells	10
Phosphorylation of ‘SDT-like’ motifs in ATRX mediates its interaction with the MRN complex and is important for ALT pathway suppression	10
2024: The quest continues	10
TRIM family proteins: roles in proteostasis and neurodegenerative diseases	9
Aspirin and cancer: biological mechanisms and clinical outcomes	9
Single-cell expression predicts neuron-specific protein homeostasis networks	9
Pigment-dispersing factor is present in circadian clock neurons of pea aphids and may mediate photoperiodic signalling to insulin-producing cells	9
Mapping molecular complexes with super-resolution microscopy and single-particle analysis	9
Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila	9
Retraction: ‘TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin’ (2016), by Wang et al.	9
Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease	9
Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin	9
Evolution and assembly of Anopheles aquasalis 's immune genes: primary malaria vector of coastal Central and South America and the Caribbean Islands	9
The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body	9
Repo-Man/protein phosphatase 1 SUMOylation mediates binding to lamin A and serine 22 dephosphorylation	9
Phylogenomic diversity of archigregarine apicomplexans	9
The post-translational modification O-GlcNAc is a sensor and regulator of metabolism	9
Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development	9
Examination of gammarid transcriptomes reveals a widespread occurrence of key metabolic genes from epibiont bdelloid rotifers in freshwater species	9
Proposed three-phenylalanine motif involved in magnetoreception signalling of an Actinopterygii protein expressed in mammalian cells	9
Cooperative motility, force generation and mechanosensing in a foraging non-photosynthetic diatom	9
Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections	9
The gender-specific impact of starvation on mitotypes diversity in adults of Drosophila melanogaster	9