OOIR: Observatory of International Research

Papers

(The TQCC of Open Biology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod	133
A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis	101
MYH7 R453C induced cardiac remodelling via activating TGF-β/Smad2/3, ERK1/2 and Nox4/ROS/NF-κB signalling pathways	99
Cosegregation of asymmetric features during cell division	77
Nutrient-sensitive protein O-GlcNAcylation shapes daily biological rhythms	73
Correction to: ‘Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae ’ (2024),	69
Visualization of sympathetic neural innervation in human white adipose tissue	63
Into the second decade	48
Decoding life's inner workings: advances in quantitative bioimaging	47
Retraction: ‘HOXD-AS1 confers cisplatin resistance in gastric cancer through epigenetically silencing PDCD4 via recruiting EZH2’ (2019), by Ye et al.	47
Comparative mitogenomic analysis and phylogeny of Veneridae with doubly uniparental inheritance	44
Limitations of sequence dissimilarity as a predictor of prokaryotic lineage	43
Intrinsically disordered proteins: modes of binding with emphasis on disordered domains	41
RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication	41
Oxidized phospholipid damage signals as modulators of immunity	40
Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours	39
Risk factors for severe COVID-19 disease increase SARS-CoV-2 infectivity of endothelial cells and pericytes	38
Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?	37
SID-2 is a conserved extracellular vesicle protein that is not associated with environmental RNAi in parasitic nematodes	36
From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs	36
Integrative analysis of genomic and transcriptomic alterations of AGR2 and AGR3 in cancer	36
Pleiotropic effects on proliferation and mineralization of primary human adipose tissue-derived stromal cells induced by simvastatin	35
Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and its impact on neuron biology	35
Transiently restricting individual amino acids protects Drosophila melanogaster against multiple stressors	34
SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation	33

Identification and characterization of host miRNAs that target the mouse mammary tumour virus (MMTV) genome	32
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system	32
NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors	31
Complement receptor 3-dependent engagement by Candida glabrata β-glucan modulates dendritic cells to induce regulatory T-cell expansion	31
The first genetic engineered system for ovothiol biosynthesis in diatoms reveals a mitochondrial localization for the sulfoxide synthase OvoA	31
Essential roles of the nucleolus during early embryonic development: a regulatory hub for chromatin organization	30
Every good biologist deserves favour	30
Min oscillations in bacteria as real-time reporter of environmental challenges at the single-cell level	30
A new view of axon growth and guidance grounded in the stochastic dynamics of actin networks	29
Retraction: ‘Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial-mesenchymal transition by regulating HIF-1α via miR-138’	29
Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p27	28
Arabidopsis thaliana endonuclease V is a ribonuclease specific for inosine-containing single-stranded RNA	28
In vitro reconstitution of substrate S-acylation by the zDHHC family of protein acyltransferases	26
A fast-growing dengue virus mutant reveals a dual role of STING in response to infection	26
Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response	26
Footprints in the Sno: investigating the cellular and molecular mechanisms of SNORD116	25
Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae	25
Retraction: ‘Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p’ (2020), by Cui et al.	24
The genetic basis and potential molecular mechanism of yellow-albino northern snakehead (Channa argus)	24
Au naturale: use of biologically derived cyclic di-nucleotides for cancer immunotherapy	24
Pck2 association with the plasma membrane and efficient response of the cell integrity pathway require regulation of PI4P homeostasis by exomer	24
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation	24
The role of α-sheet structure in amyloidogenesis: characterization and implications	23
Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism	23
Correction to ‘Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments’ (2022) by Kellom et al .	23
Interplay between circadian rhythm, ageing and neurodegenerative disorder	22
Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics	22
The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint	21
Multifunctional roles of Sec13 paralogues in the euglenozoan Trypanosoma brucei	20
Proteomic comparison of the organic matrices from parietal and base plates of the acorn barnacle Amphibalanus amphitrite	20
Reversible bacteriophage resistance by shedding the bacterial cell wall	20
Learning-induced remodelling of inhibitory synapses in the motor cortex	19
Stepwise order in protein complex assembly: approaches and emerging themes	19
Light-induced reversible reorganizations in closed Type II reaction centre complexes: physiological roles and physical mechanisms	19
Polycomb-mediated transgenerational epigenetic inheritance of Drosophila eye colour is independent of small RNAs	19
C-terminal glycosylation of type IX secretion system cargo proteins in Prevotella intermedia with both short and long secretion signals	19
A circle of life: platelet and megakaryocyte cytoskeleton dynamics in health and disease	18
Genome-wide identification of ATP-binding cassette transporter B subfamily, focusing on its structure, evolution and rearrangement in ciliates	18
miR-155-3p: processing by-product or rising star in immunity and cancer?	18
Neuronal signalling of zinc: from detection and modulation to function	18
Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria	18
Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation	17
Temperature activated transient receptor potential ion channels from Antarctic fishes	17
Long-read RNA-sequencing reveals transcript-specific regulation in human-derived cortical neurons	17
Whole organism and tissue-specific analysis of pexophagy in Drosophila	16
Expression of concern: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui Y et al.	16
Aurodox inhibits type III secretion in multiple Gram-negative pathogens	16
The supernumerary B chromosome of maize: drive and genomic conflict	16
Spatial transcriptomes and microbiota reveal immune mechanism that respond to pathogen infection in the posterior intestine ofSebastes schlegelii	15
The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex	15

GNL3 is an evolutionarily conserved stem cell gene influencing cell proliferation, animal growth and regeneration in the hydrozoan Hydractinia	15
Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells	15
MicroRNAs: master regulators in host–parasitic protist interactions	14
Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis	14
Identification of the modulatory Ca ²⁺ -binding sites of acid-sensing ion channel 1a	14
Exploring the midgut physiology of the non-haematophagous mosquito Toxorhynchites theobaldi	14
Unravelling axonal transcriptional landscapes: insights from induced pluripotent stem cell-derived cortical neurons and implications for motor neuron degeneration	14
Retraction: ‘MALAT1 promotes gastric adenocarcinoma through the MALAT1/miR-181a-5p/AKT3 axis’ (2019), by Lu et al.	14
Decoding frontotemporal and cell-type-specific vulnerabilities to neuropsychiatric disorders and psychoactive drugs	14
Retraction: ‘Long non-coding RNA LINC00467 regulates hepatocellular carcinoma progression by modulating miR-9-5p/PPARA expression’ (2019), by Cai et al.	14
Effective training of nanopore callers for epigenetic marks with limited labelled data	14
GLP-1/GLP-1R axis: from metabolism (obesity and T2DM) to immunity	13
Terminal regions of a protein are a hotspot for low complexity regions and selection	13
Centromere function in asymmetric cell division in Drosophila female and male germline stem cells	13
Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m ⁷ G-cap-dependent translation at the 8- to 16-cell transition	13
PIEZO1 variant implications for biological understanding and human health	13
Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction	13
Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades	13
Exploring differential exon usage via short- and long-read RNA sequencing strategies	13
Plant NLR immunity activation and execution: a biochemical perspective	13
Mapping combinatorial expression of non-clustered protocadherins in the developing brain identifies novel PCDH19-mediated cell adhesion properties	13
The challenge of measuring mosquito flight performance: going beyond sterile insect technique and into transgenic and gene drive-based approaches	13
Daughter centrioles assemble preferentially towards the nuclear envelope in Drosophila syncytial embryos	13
Insights into the bioluminescence systems of three sea pens (Cnidaria: Anthozoa): from de novo transcriptome analyses to biochemical assays	12
A simple inland culture system provides insights into ascidian post-embryonic developmental physiology	12
Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders	12
Polo-like kinase and Aurora B kinase phosphorylate and cooperate with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei	12
Capturing crop adaptation to abiotic stress using image-based technologies	12
PACS deficiency disrupts Golgi architecture and causes cytokinesis failures and seizure-like phenotype in Drosophila melanogaster	12
Phosphorylation of ‘SDT-like’ motifs in ATRX mediates its interaction with the MRN complex and is important for ALT pathway suppression	12
Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development	12
Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS	12
Pseudogenization of NK3 homeobox 2 ( Nkx3.2 ) in monotremes provides insight into unique gastric anatomy and physiology	12
Lysosomal positioning diseases: beyond substrate storage	12
The proline-rich antimicrobial peptide B7-005: low bacterial resistance, safe for human cells and effective in zebrafish embryo bacteraemia model	12
Single-cell expression predicts neuron-specific protein homeostasis networks	11
Time-optimized feeding is beneficial without enforced fasting	11
Pigment-dispersing factor is present in circadian clock neurons of pea aphids and may mediate photoperiodic signalling to insulin-producing cells	11
Expression and function of PDGF-C in development and stem cells	11
Evolution and assembly of Anopheles aquasalis 's immune genes: primary malaria vector of coastal Central and South America and the Caribbean Islands	11
TRIM family proteins: roles in proteostasis and neurodegenerative diseases	11
2024: The quest continues	11
Plum modulates Myoglianin and regulates synaptic function in D. melanogaster	11
Aspirin and cancer: biological mechanisms and clinical outcomes	11
Examination of gammarid transcriptomes reveals a widespread occurrence of key metabolic genes from epibiont bdelloid rotifers in freshwater species	10
Phylogenomic diversity of archigregarine apicomplexans	10
Cooperative motility, force generation and mechanosensing in a foraging non-photosynthetic diatom	10
The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body	10
Retraction: ‘TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin’ (2016), by Wang et al.	10
Proposed three-phenylalanine motif involved in magnetoreception signalling of an Actinopterygii protein expressed in mammalian cells	10
Distinct molecular profile of the chick organizer as a stem zone during axial elongation	10
Retraction: ‘Involvement of miR-4262 in paclitaxel resistance through the regulation of PTEN in non-small cell lung cancer’ (2019), by Sun et al.	10
The gender-specific impact of starvation on mitotypes diversity in adults of Drosophila melanogaster	10
Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin	10
Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease	10
High-throughput functional analysis provides novel insight into type VII secretion in Staphylococcus aureus	10
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH	10
Mapping molecular complexes with super-resolution microscopy and single-particle analysis	10
Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells	10
Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila	9
The post-translational modification O-GlcNAc is a sensor and regulator of metabolism	9
Cancer cells’ chamber of secrets: the link between micronuclei, chromothripsis and malignancy	9
Repo-Man/protein phosphatase 1 SUMOylation mediates binding to lamin A and serine 22 dephosphorylation	9
Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections	9
Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments	9
Prebiotic chemistry: a review of nucleoside phosphorylation and polymerization	9
Modern and prebiotic amino acids support distinct structural profiles in proteins	9
Biochemistry and physiology of voltage-gated calcium channel trafficking: a target for gabapentinoid drugs	9
The intrinsically disorderly story of Ki-67	9