Open Biology

Papers
(The TQCC of Open Biology is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
Wound healing: cellular mechanisms and pathological outcomes496
Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines215
Biosynthesis and biology of mammalian GPI-anchored proteins158
Anti-cancer peptides: classification, mechanism of action, reconstruction and modification116
Euglenozoa: taxonomy, diversity and ecology, symbioses and viruses96
Higher-order organization of biomolecular condensates93
Hallmarks of cancer—the new testament92
The rise and rise of mitochondrial DNA mutations85
Metarhizium: jack of all trades, master of many77
Bacterial chromosome segregation by the ParABS system72
Satellite cells in ageing: use it or lose it68
KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease67
Expression of SARS-CoV-2 receptor ACE2 and the protease TMPRSS2 suggests susceptibility of the human embryo in the first trimester65
Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential59
The centromere comes into focus: from CENP-A nucleosomes to kinetochore connections with the spindle59
The origin of animals: an ancestral reconstruction of the unicellular-to-multicellular transition58
To form and function: on the role of basement membrane mechanics in tissue development, homeostasis and disease57
Molecular mechanisms of olfactory detection in insects: beyond receptors55
Mechanisms of immune suppression by myeloid-derived suppressor cells: the role of interleukin-10 as a key immunoregulatory cytokine54
SARS-CoV-2 envelope protein topology in eukaryotic membranes53
An miRNA fingerprint using neural-enriched extracellular vesicles from blood plasma: towards a biomarker for amyotrophic lateral sclerosis/motor neuron disease48
Black box of phage–bacterium interactions: exploring alternative phage infection strategies47
Senescent cells and macrophages: key players for regeneration?46
Walking the tight wire between cell adhesion and WNT signalling: a balancing act for β-catenin44
The multifarious regulation of the apical junctional complex43
ADAMTS proteases in cardiovascular physiology and disease41
Fibro-adipogenic progenitors in skeletal muscle homeostasis, regeneration and diseases40
Ubiquitin–proteasome system and the role of its inhibitors in cancer therapy38
Adipose tissue in health and disease37
Role of antioxidants and a nutrient rich diet in Alzheimer's disease37
Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues35
Therapeutic potential of astaxanthin and superoxide dismutase in Alzheimer's disease35
A duplicated amh is the master sex-determining gene for Sebastes rockfish in the Northwest Pacific34
Regulation of ecdysone production in Drosophila by neuropeptides and peptide hormones34
Substrate recruitment by zDHHC protein acyltransferases33
The intrinsically disorderly story of Ki-6732
CAP-MAP: cap analysis protocol with minimal analyte processing, a rapid and sensitive approach to analysing mRNA cap structures31
The evolutionary origins of the vertebrate olfactory system31
Intrinsically disordered proteins: modes of binding with emphasis on disordered domains30
What do editors do? Understanding the physiological functions of A-to-I RNA editing by adenosine deaminase acting on RNAs30
Pathways shaping the mitochondrial inner membrane30
Molecular mechanisms behind mRNA localization in axons29
Modulators of calcium signalling at fertilization28
Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories27
Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders27
Schwann cell remyelination of the central nervous system: why does it happen and what are the benefits?27
Phosphoglycerate kinase: structural aspects and functions, with special emphasis on the enzyme from Kinetoplastea27
The crosstalk between microtubules, actin and membranes shapes cell division27
Syndecan receptors: pericellular regulators in development and inflammatory disease26
Molecular and functional characterization of somatostatin-type signalling in a deuterostome invertebrate26
Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronized cell cycle progression in human cell culture26
How do the Fat–Dachsous and core planar polarity pathways act together and independently to coordinate polarized cell behaviours?26
Brain and testis: more alike than previously thought?26
‘High vault-age’: non-coding RNA control of autophagy25
Darwin's bark spider shares a spidroin repertoire with Caerostris extrusa but achieves extraordinary silk toughness through gene expression24
A complete enzymatic capacity for biosynthesis of docosahexaenoic acid (DHA, 22 : 6n–3) exists in the marine Harpacticoida copepod Tigriopus californicus24
A centriole's subdistal appendages: contributions to cell division, ciliogenesis and differentiation24
Trypanosoma cruzi amastigotes that persist in the colon during chronic stage murine infections have a reduced replication rate24
Genome instability and loss of protein homeostasis: converging paths to neurodegeneration?24
The role of disorder in RNA binding affinity and specificity24
Insight into m 6 A methylation from occurrence to functions24
The structure and function of deubiquitinases: lessons from budding yeast24
Endothelial cells, neutrophils and platelets: getting to the bottom of an inflammatory triangle24
Endocrine cybernetics: neuropeptides as molecular switches in behavioural decisions24
Repurposing of synaptonemal complex proteins for kinetochores in Kinetoplastida23
Molecular insights into the powerful mucus-based adhesion of limpets ( Patella vulgata L.)23
Viral pathogenesis of SARS-CoV-2 infection and male reproductive health23
Reversible bacteriophage resistance by shedding the bacterial cell wall22
Signalling through cerebral cavernous malformation protein networks22
TAK1: a potent tumour necrosis factor inhibitor for the treatment of inflammatory diseases21
Notch signalling in healthy and diseased vasculature21
Alterations of the endocannabinoid system and its therapeutic potential in autism spectrum disorder21
The interesting relationship between APOBEC3 deoxycytidine deaminases and cancer: a long road ahead21
Gut instincts: vitamin D/vitamin D receptor and microbiome in neurodevelopment disorders21
Protein S -palmitoylation in immunity21
SIRT7: a sentinel of genome stability21
Temperature modulates immune gene expression in mosquitoes during arbovirus infection20
Ultrastructure expansion microscopy in Trypanosoma brucei20
Non-apoptotic roles of apoptotic proteases: new tricks for an old dog20
Vascular underpinning of COVID-1920
Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells20
The impact of autophagy during the development and survival of glioblastoma20
Unravelling the mystery of female meiotic drive: where we are20
The FBXL family of F-box proteins: variations on a theme19
Prader-Willi syndrome: reflections on seminal studies and future therapies19
Metabolomics of human fasting: new insights about old questions18
Centrosome-centric view of asymmetric stem cell division18
Telomeric replication stress: the beginning and the end for alternative lengthening of telomeres cancers18
The mitochondrial intermembrane space: the most constricted mitochondrial sub-compartment with the largest variety of protein import pathways18
Long non-coding RNA-polycomb intimate rendezvous18
HIV Rev-isited18
What determines eukaryotic translation elongation: recent molecular and quantitative analyses of protein synthesis17
Exploring the therapeutic potential of forkhead box O for outfoxing COVID-1917
Alzheimer's disease-like perturbations in HIV-mediated neuronal dysfunctions: understanding mechanisms and developing therapeutic strategies17
RETRACTED: Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p17
Mechanotransduction as a major driver of cell behaviour: mechanisms, and relevance to cell organization and future research17
Cellular and molecular mechanisms that regulate mammalian digit tip regeneration17
A high-throughput assay for directly monitoring nucleolar rRNA biogenesis17
The aerobic mitochondrial ATP synthesis from a comprehensive point of view17
Molecular anatomy of the pre-primitive-streak chick embryo17
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system17
Novel perspectives of target-binding by the evolutionarily conserved PP4 phosphatase17
RNA polymerase II pausing in development: orchestrating transcription16
Parallel evolution of trehalose production machinery in anhydrobiotic animals via recurrent gene loss and horizontal transfer16
SUMOylation modification-mediated cell death16
Controlling the topology of mammalian mitochondrial DNA16
Fibroblast growth factor receptor signalling dysregulation and targeting in breast cancer16
The plastic cell: mechanical deformation of cells and tissues16
The role of Wnt signalling in development of coronary artery disease and its risk factors16
Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis15
An early Sox2-dependent gene expression programme required for hippocampal dentate gyrus development15
Topoisomerase IIα prevents ultrafine anaphase bridges by two mechanisms15
Injury-induced Cavl-expressing cells at lesion rostral side play major roles in spinal cord regeneration15
Functions of exogenous FGF signals in regulation of fibroblast to myofibroblast differentiation and extracellular matrix protein expression15
The multifaceted role of vitamin B 6 in cancer: Drosophila as a model system to investigate DNA damage15
Proteolytic activity of the proteasome is required for female insect reproduction15
The contribution of non-coding regulatory elements to cardiovascular disease15
Extracellular matrix guidance of autophagy: a mechanism regulating cancer growth15
Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections15
Capturing crop adaptation to abiotic stress using image-based technologies15
SUMOylation in the control of cholesterol homeostasis14
Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p2714
Radiation combines with immune checkpoint blockade to enhance T cell priming in a murine model of poorly immunogenic pancreatic cancer14
RETRACTED: DDP-resistant ovarian cancer cells-derived exosomal microRNA-30a-5p reduces the resistance of ovarian cancer cells to DDP14
Development of the mammalian cortical hem and its derivatives: the choroid plexus, Cajal–Retzius cells and hippocampus14
The pVHL neglected functions, a tale of hypoxia-dependent and -independent regulations in cancer14
Zinc-α2-glycoprotein as an inhibitor of amine oxidase copper-containing 314
PGE 2 upregulates gene expression of dual oxidase in a lepidopteran insect midgut via cAMP signalling pathway14
Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and its impact on neuron biology14
ANGPTL8 in metabolic homeostasis: more friend than foe?14
Lysosomal positioning diseases: beyond substrate storage13
Diversity from similarity: cellular strategies for assigning particular identities to actin filaments and networks13
Expansion microscopy facilitates quantitative super-resolution studies of cytoskeletal structures in kinetoplastid parasites13
The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation13
Establishment and function of chromatin modification at enhancers13
Driving forces in the origins of life12
Role of amylopectin synthesis in Toxoplasma gondii and its implication in vaccine development against toxoplasmosis12
Palmitoylation of Hedgehog proteins by Hedgehog acyltransferase: roles in signalling and disease12
Exploiting aneuploidy-imposed stresses and coping mechanisms to battle cancer12
Ghrelin octanoylation by ghrelin O -acyltransferase: protein acylation impacting metabolic and neuroendocrine signalling12
Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature12
Genomic instability and cancer: lessons from Drosophila12
Human intestinal models to study interactions between intestine and microbes12
Neutrophil interactions with the sexually transmitted parasite Trichomonas vaginalis: implications for immunity and pathogenesis12
Iron-sulfur flavoenzymes: the added value of making the most ancient redox cofactors and the versatile flavins work together12
Mechanism and regulation of P element transposition12
Haloferax volcanii —a model archaeon for studying DNA replication and repair12
Convalescent plasma therapy: a promising coronavirus disease 2019 treatment strategy12
TRIM family proteins: roles in proteostasis and neurodegenerative diseases12
Comparative analysis of stalked and acorn barnacle adhesive proteomes12
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