OOIR: Observatory of International Research

Papers

(The TQCC of Open Biology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Euglenozoa: taxonomy, diversity and ecology, symbioses and viruses	123
Hallmarks of cancer—the new testament	121
Higher-order organization of biomolecular condensates	116
Metarhizium: jack of all trades, master of many	103
The origin of animals: an ancestral reconstruction of the unicellular-to-multicellular transition	83
To form and function: on the role of basement membrane mechanics in tissue development, homeostasis and disease	80
Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential	68
Black box of phage–bacterium interactions: exploring alternative phage infection strategies	68
Fibro-adipogenic progenitors in skeletal muscle homeostasis, regeneration and diseases	65
Walking the tight wire between cell adhesion and WNT signalling: a balancing act for β-catenin	59
Senescent cells and macrophages: key players for regeneration?	58
Ubiquitin–proteasome system and the role of its inhibitors in cancer therapy	54
Intrinsically disordered proteins: modes of binding with emphasis on disordered domains	52
Therapeutic potential of astaxanthin and superoxide dismutase in Alzheimer's disease	50
A duplicated amh is the master sex-determining gene for Sebastes rockfish in the Northwest Pacific	49
ADAMTS proteases in cardiovascular physiology and disease	49
Adipose tissue in health and disease	48
The intrinsically disorderly story of Ki-67	47
Pathways shaping the mitochondrial inner membrane	46
Substrate recruitment by zDHHC protein acyltransferases	45
The role of disorder in RNA binding affinity and specificity	44
Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections	44
Regulation of ecdysone production in Drosophila by neuropeptides and peptide hormones	44
The evolutionary origins of the vertebrate olfactory system	41
Brain and testis: more alike than previously thought?	40

Endocrine cybernetics: neuropeptides as molecular switches in behavioural decisions	38
Syndecan receptors: pericellular regulators in development and inflammatory disease	37
Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders	37
Phosphoglycerate kinase: structural aspects and functions, with special emphasis on the enzyme from Kinetoplastea	36
A complete enzymatic capacity for biosynthesis of docosahexaenoic acid (DHA, 22 : 6n–3) exists in the marine Harpacticoida copepod Tigriopus californicus	34
How do the Fat–Dachsous and core planar polarity pathways act together and independently to coordinate polarized cell behaviours?	34
SUMOylation modification-mediated cell death	34
Notch signalling in healthy and diseased vasculature	33
Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories	32
Schwann cell remyelination of the central nervous system: why does it happen and what are the benefits?	32
Ultrastructure expansion microscopy in Trypanosoma brucei	31
Genome instability and loss of protein homeostasis: converging paths to neurodegeneration?	31
Unravelling the mystery of female meiotic drive: where we are	31
Darwin's bark spider shares a spidroin repertoire with Caerostris extrusa but achieves extraordinary silk toughness through gene expression	31
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system	30
Protein S -palmitoylation in immunity	29
Reversible bacteriophage resistance by shedding the bacterial cell wall	29
Temperature modulates immune gene expression in mosquitoes during arbovirus infection	29
Trypanosoma cruzi amastigotes that persist in the colon during chronic stage murine infections have a reduced replication rate	28
Repurposing of synaptonemal complex proteins for kinetochores in Kinetoplastida	28
SIRT7: a sentinel of genome stability	27
The interesting relationship between APOBEC3 deoxycytidine deaminases and cancer: a long road ahead	27
Alterations of the endocannabinoid system and its therapeutic potential in autism spectrum disorder	27
Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells	27
Signalling through cerebral cavernous malformation protein networks	26
RNA polymerase II pausing in development: orchestrating transcription	26
A centriole's subdistal appendages: contributions to cell division, ciliogenesis and differentiation	26
Viral pathogenesis of SARS-CoV-2 infection and male reproductive health	26
Telomeric replication stress: the beginning and the end for alternative lengthening of telomeres cancers	25
Fibroblast growth factor receptor signalling dysregulation and targeting in breast cancer	25
Parallel evolution of trehalose production machinery in anhydrobiotic animals via recurrent gene loss and horizontal transfer	25
HIV Rev-isited	25
The mitochondrial intermembrane space: the most constricted mitochondrial sub-compartment with the largest variety of protein import pathways	24
Secondary cell wall patterning—connecting the dots, pits and helices	24
Controlling the topology of mammalian mitochondrial DNA	24
Ferroptosis in myocardial infarction: not a marker but a maker	24
Exploring the therapeutic potential of forkhead box O for outfoxing COVID-19	23
Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p27	23
Functions of exogenous FGF signals in regulation of fibroblast to myofibroblast differentiation and extracellular matrix protein expression	23
What determines eukaryotic translation elongation: recent molecular and quantitative analyses of protein synthesis	22
Mechanotransduction as a major driver of cell behaviour: mechanisms, and relevance to cell organization and future research	22
The plastic cell: mechanical deformation of cells and tissues	22
Capturing crop adaptation to abiotic stress using image-based technologies	22
Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature	22
The FBXL family of F-box proteins: variations on a theme	22
Haloferax volcanii —a model archaeon for studying DNA replication and repair	21
A high-throughput assay for directly monitoring nucleolar rRNA biogenesis	21
Aspirin and cancer: biological mechanisms and clinical outcomes	21
Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis	21
Mechanisms driving spatial distribution of residents in colony biofilms: an interdisciplinary perspective	21

Centrosome-centric view of asymmetric stem cell division	20
Expansion microscopy facilitates quantitative super-resolution studies of cytoskeletal structures in kinetoplastid parasites	20
How neutrophil metabolism affects bacterial killing	20
Patterning principles of morphogen gradients	20
An early Sox2-dependent gene expression programme required for hippocampal dentate gyrus development	19
ANGPTL8 in metabolic homeostasis: more friend than foe?	19
Development of the mammalian cortical hem and its derivatives: the choroid plexus, Cajal–Retzius cells and hippocampus	19
Novel perspectives of target-binding by the evolutionarily conserved PP4 phosphatase	19
The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation	19
Extracellular matrix guidance of autophagy: a mechanism regulating cancer growth	18
Alzheimer's disease-like perturbations in HIV-mediated neuronal dysfunctions: understanding mechanisms and developing therapeutic strategies	18
Structure of the Ndc80 complex and its interactions at the yeast kinetochore–microtubule interface	18
TRIM family proteins: roles in proteostasis and neurodegenerative diseases	18
Lysosomal positioning diseases: beyond substrate storage	18
Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics	18
Proteolytic activity of the proteasome is required for female insect reproduction	18
Injury-induced Cavl-expressing cells at lesion rostral side play major roles in spinal cord regeneration	17
Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and its impact on neuron biology	16
The role of procoagulant phospholipids on the surface of circulating blood cells in thrombosis and haemostasis	16
Driving forces in the origins of life	16
The closest lineage of Archaeplastida is revealed by phylogenomics analyses that include Microheliella maris	16
Palmitoylation of Hedgehog proteins by Hedgehog acyltransferase: roles in signalling and disease	16
Radiation combines with immune checkpoint blockade to enhance T cell priming in a murine model of poorly immunogenic pancreatic cancer	16
The aldehyde hypothesis: metabolic intermediates as antimicrobial effectors	15
An open-source pipeline for analysing changes in microglial morphology	15
Iron-sulfur flavoenzymes: the added value of making the most ancient redox cofactors and the versatile flavins work together	15
Cell cycle-dependent binding between Cyclin B1 and Cdk1 revealed by time-resolved fluorescence correlation spectroscopy	15
Role of amylopectin synthesis in Toxoplasma gondii and its implication in vaccine development against toxoplasmosis	15
The supernumerary B chromosome of maize: drive and genomic conflict	15
Pareto optimality, economy–effectiveness trade-offs and ion channel degeneracy: improving population modelling for single neurons	15
Mechanism and regulation of P element transposition	14
Neuronal signalling of zinc: from detection and modulation to function	14
The genetic basis and potential molecular mechanism of yellow-albino northern snakehead (Channa argus)	14
Molecular mechanisms of developmental pathways in neurological disorders: a pharmacological and therapeutic review	14
Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria	14
Reconstitution of the recombinant human γ-tubulin ring complex	14
Blood–brain barrier disruption in atrial fibrillation: a potential contributor to the increased risk of dementia and worsening of stroke outcomes?	14
Modern and prebiotic amino acids support distinct structural profiles in proteins	14
Ghrelin octanoylation by ghrelinO-acyltransferase: protein acylation impacting metabolic and neuroendocrine signalling	14
Age separation dramatically reduces COVID-19 mortality rate in a computational model of a large population	13
Opinion: PARP inhibitors in cancer—what do we still need to know?	13
Metamorphic proteins: the Janus proteins of structural biology	13
Maintenance and loss of endocytic organelle integrity: mechanisms and implications for antigen cross-presentation	13
A glitch in the snitch: the role of linker histone H1 in shaping the epigenome in normal and diseased cells	13
Comparative analysis of stalked and acorn barnacle adhesive proteomes	13
Mitochondrial biology and dysfunction in secondary mitochondrial disease	12
Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties	12
Jack of all trades, master of each: the diversity of fibroblast growth factor signalling in eye development	12
Modelling population dynamics in a unicellular social organism community using a minimal model and evolutionary game theory	12
ATP-dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming	12
MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex	12
MicroRNAs: master regulators in host–parasitic protist interactions	12
miR-155-3p: processing by-product or rising star in immunity and cancer?	12
Live imaging YAP signalling in mouse embryo development	12
Regulating the regulator: a survey of mechanisms from transcription to translation controlling expression of mammalian cell cycle kinase Aurora A	12
Epidemiological profiles and associated risk factors of SARS-CoV-2 positive patients based on a high-throughput testing facility in India	12
Emerging roles of centrosome cohesion	12
Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism	12
Shared evolutionary footprints suggest mitochondrial oxidative damage underlies multiple complex I losses in fungi	12
Tweedle proteins form extracellular two-dimensional structures defining body and cell shape in Drosophila melanogaster	11
Functional characterization of the human Cdk10/Cyclin Q complex	11
Implication of synaptotagmins 4 and 7 in activity-dependent somatodendritic dopamine release in the ventral midbrain	11
The three-component helicase/primase complex of herpes simplex virus-1	11
The inherent flexibility of type I non-ribosomal peptide synthetase multienzymes drives their catalytic activities	11
Structural basis for the coiled-coil architecture of human CtIP	11
Ovothiol ensures the correct developmental programme of the sea urchin Paracentrotus lividus embryo	11
Appendage regeneration is context dependent at the cellular level	11
A genetic model for in vivo proximity labelling of the mammalian secretome	11
Determination of the membrane topology of PORCN, an O-acyl transferase that modifies Wnt signalling proteins	11
A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis	11