Open Biology

Papers
(The median citation count of Open Biology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Visualization of sympathetic neural innervation in human white adipose tissue142
Into the second decade109
Retraction: ‘HOXD-AS1 confers cisplatin resistance in gastric cancer through epigenetically silencing PDCD4 via recruiting EZH2’ (2019), by Ye et al.103
Decoding life's inner workings: advances in quantitative bioimaging78
Comparative mitogenomic analysis and phylogeny of Veneridae with doubly uniparental inheritance70
Limitations of sequence dissimilarity as a predictor of prokaryotic lineage66
A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis50
Correction to: ‘Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae ’ (2024), 49
Nutrient-sensitive protein O-GlcNAcylation shapes daily biological rhythms49
Oxidized phospholipid damage signals as modulators of immunity46
MYH7 R453C induced cardiac remodelling via activating TGF-β/Smad2/3, ERK1/2 and Nox4/ROS/NF-κB signalling pathways44
RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication42
Intrinsically disordered proteins: modes of binding with emphasis on disordered domains41
Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours41
Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p2739
A new view of axon growth and guidance grounded in the stochastic dynamics of actin networks39
From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs39
Risk factors for severe COVID-19 disease increase SARS-CoV-2 infectivity of endothelial cells and pericytes38
Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?37
Integrative analysis of genomic and transcriptomic alterations of AGR2 and AGR3 in cancer36
SID-2 is a conserved extracellular vesicle protein that is not associated with environmental RNAi in parasitic nematodes36
Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and its impact on neuron biology36
Pleiotropic effects on proliferation and mineralization of primary human adipose tissue-derived stromal cells induced by simvastatin35
Transiently restricting individual amino acids protects Drosophila melanogaster against multiple stressors34
Identification and characterization of host miRNAs that target the mouse mammary tumour virus (MMTV) genome33
SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation33
The first genetic engineered system for ovothiol biosynthesis in diatoms reveals a mitochondrial localization for the sulfoxide synthase OvoA32
Essential roles of the nucleolus during early embryonic development: a regulatory hub for chromatin organization32
Retraction: ‘Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial-mesenchymal transition by regulating HIF-1α via miR-138’31
Min oscillations in bacteria as real-time reporter of environmental challenges at the single-cell level31
Every good biologist deserves favour31
Arabidopsis thaliana endonuclease V is a ribonuclease specific for inosine-containing single-stranded RNA31
Complement receptor 3-dependent engagement by Candida glabrata β-glucan modulates dendritic cells to induce regulatory T-cell expansion30
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system29
NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors29
Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response28
A fast-growing dengue virus mutant reveals a dual role of STING in response to infection28
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation27
Footprints in the Sno: investigating the cellular and molecular mechanisms of SNORD11627
Au naturale: use of biologically derived cyclic di-nucleotides for cancer immunotherapy26
Pck2 association with the plasma membrane and efficient response of the cell integrity pathway require regulation of PI4P homeostasis by exomer25
Retraction: ‘Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p’ (2020), by Cui et al.25
The role of α-sheet structure in amyloidogenesis: characterization and implications25
Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism24
Correction to ‘Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments’ (2022) by Kellom et al .24
The genetic basis and potential molecular mechanism of yellow-albino northern snakehead (Channa argus)24
Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics23
Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae23
Learning-induced remodelling of inhibitory synapses in the motor cortex22
In vitro reconstitution of substrate S-acylation by the zDHHC family of protein acyltransferases22
A circle of life: platelet and megakaryocyte cytoskeleton dynamics in health and disease22
Light-induced reversible reorganizations in closed Type II reaction centre complexes: physiological roles and physical mechanisms22
Long-read RNA-sequencing reveals transcript-specific regulation in human-derived cortical neurons20
Neuronal signalling of zinc: from detection and modulation to function20
Interplay between circadian rhythm, ageing and neurodegenerative disorder20
The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint20
Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation20
Multifunctional roles of Sec13 paralogues in the euglenozoan Trypanosoma brucei19
Proteomic comparison of the organic matrices from parietal and base plates of the acorn barnacle Amphibalanus amphitrite19
Reversible bacteriophage resistance by shedding the bacterial cell wall19
miR-155-3p: processing by-product or rising star in immunity and cancer?18
Stepwise order in protein complex assembly: approaches and emerging themes18
Transcriptional regulation as a dose-dependent process: insights from transcription factor tuning18
Polycomb-mediated transgenerational epigenetic inheritance of Drosophila eye colour is independent of small RNAs18
Genome-wide identification of ATP-binding cassette transporter B subfamily, focusing on its structure, evolution and rearrangement in ciliates18
C-terminal glycosylation of type IX secretion system cargo proteins in Prevotella intermedia with both short and long secretion signals18
Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria17
Whole organism and tissue-specific analysis of pexophagy in Drosophila16
Temperature activated transient receptor potential ion channels from Antarctic fishes16
The supernumerary B chromosome of maize: drive and genomic conflict16
Aurodox inhibits type III secretion in multiple Gram-negative pathogens16
PIEZO1 variant implications for biological understanding and human health15
Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells15
GNL3 is an evolutionarily conserved stem cell gene influencing cell proliferation, animal growth and regeneration in the hydrozoan Hydractinia15
Spatial transcriptomes and microbiota reveal immune mechanism that respond to pathogen infection in the posterior intestine ofSebastes schlegelii15
Expression of concern: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui Y et al.15
Unravelling axonal transcriptional landscapes: insights from induced pluripotent stem cell-derived cortical neurons and implications for motor neuron degeneration14
The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex14
Decoding frontotemporal and cell-type-specific vulnerabilities to neuropsychiatric disorders and psychoactive drugs14
Identification of the modulatory Ca 2+ -binding sites of acid-sensing ion channel 1a14
Retraction: ‘Long non-coding RNA LINC00467 regulates hepatocellular carcinoma progression by modulating miR-9-5p/PPARA expression’ (2019), by Cai et al.14
MicroRNAs: master regulators in host–parasitic protist interactions14
Retraction: ‘MALAT1 promotes gastric adenocarcinoma through the MALAT1/miR-181a-5p/AKT3 axis’ (2019), by Lu et al.14
Exploring the midgut physiology of the non-haematophagous mosquito Toxorhynchites theobaldi14
Effective training of nanopore callers for epigenetic marks with limited labelled data14
Centromere function in asymmetric cell division in Drosophila female and male germline stem cells13
Plant NLR immunity activation and execution: a biochemical perspective13
Exploring differential exon usage via short- and long-read RNA sequencing strategies13
Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m 7 G-cap-dependent translation at the 8- to 16-cell transition13
Mapping combinatorial expression of non-clustered protocadherins in the developing brain identifies novel PCDH19-mediated cell adhesion properties13
Terminal regions of a protein are a hotspot for low complexity regions and selection13
Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis13
Pseudogenization of NK3 homeobox 2 ( Nkx3.2 ) in monotremes provides insight into unique gastric anatomy and physiology13
Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades13
GLP-1/GLP-1R axis: from metabolism (obesity and T2DM) to immunity13
Lysosomal positioning diseases: beyond substrate storage13
Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction13
Daughter centrioles assemble preferentially towards the nuclear envelope in Drosophila syncytial embryos12
PACS deficiency disrupts Golgi architecture and causes cytokinesis failures and seizure-like phenotype in Drosophila melanogaster12
Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders12
Insights into the bioluminescence systems of three sea pens (Cnidaria: Anthozoa): from de novo transcriptome analyses to biochemical assays12
A simple inland culture system provides insights into ascidian post-embryonic developmental physiology12
Polo-like kinase and Aurora B kinase phosphorylate and cooperate with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei12
The challenge of measuring mosquito flight performance: going beyond sterile insect technique and into transgenic and gene drive-based approaches12
Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS12
Capturing crop adaptation to abiotic stress using image-based technologies12
Phosphorylation of ‘SDT-like’ motifs in ATRX mediates its interaction with the MRN complex and is important for ALT pathway suppression11
Single-cell expression predicts neuron-specific protein homeostasis networks11
Evolution and assembly of Anopheles aquasalis 's immune genes: primary malaria vector of coastal Central and South America and the Caribbean Islands11
Examination of gammarid transcriptomes reveals a widespread occurrence of key metabolic genes from epibiont bdelloid rotifers in freshwater species11
The proline-rich antimicrobial peptide B7-005: low bacterial resistance, safe for human cells and effective in zebrafish embryo bacteraemia model11
Plum modulates Myoglianin and regulates synaptic function in D. melanogaster11
Discovery of unique mitotic mechanisms in Paradiplonema papillatum11
2024: The quest continues11
Time-optimized feeding is beneficial without enforced fasting11
Aspirin and cancer: biological mechanisms and clinical outcomes10
TRIM family proteins: roles in proteostasis and neurodegenerative diseases10
Pigment-dispersing factor is present in circadian clock neurons of pea aphids and may mediate photoperiodic signalling to insulin-producing cells10
Proposed three-phenylalanine motif involved in magnetoreception signalling of an Actinopterygii protein expressed in mammalian cells10
Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin10
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH10
Distinct molecular profile of the chick organizer as a stem zone during axial elongation10
Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease10
Expression and function of PDGF-C in development and stem cells10
Retraction: ‘TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin’ (2016), by Wang et al.10
Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells10
Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development10
Retraction: ‘Involvement of miR-4262 in paclitaxel resistance through the regulation of PTEN in non-small cell lung cancer’ (2019), by Sun et al.9
High-throughput functional analysis provides novel insight into type VII secretion in Staphylococcus aureus9
Prebiotic chemistry: a review of nucleoside phosphorylation and polymerization9
The gender-specific impact of starvation on mitotypes diversity in adults of Drosophila melanogaster9
Cooperative motility, force generation and mechanosensing in a foraging non-photosynthetic diatom9
Repo-Man/protein phosphatase 1 SUMOylation mediates binding to lamin A and serine 22 dephosphorylation9
Modern and prebiotic amino acids support distinct structural profiles in proteins9
Phylogenomic diversity of archigregarine apicomplexans9
Mapping molecular complexes with super-resolution microscopy and single-particle analysis9
The post-translational modification O-GlcNAc is a sensor and regulator of metabolism9
Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila9
The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body8
Efficient CRISPR/Cas9-mediated gene disruption in the tetraploid protist Giardia intestinalis8
Intense light unleashes male–male courtship behaviour in wild-type Drosophila8
Biochemistry and physiology of voltage-gated calcium channel trafficking: a target for gabapentinoid drugs8
Multiple factors contribute to female dominance in migratory bioflows8
A diversified and segregated mRNA spliced-leader system in the parasitic Perkinsozoa8
Expression of concern: ‘TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin’ (2016), by Wang N et al.8
O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control8
Quantifying the large-scale chromosome structural dynamics during the mitosis-to-G1 phase transition of cell cycle8
Expression of concern: DDP-resistant ovarian cancer cells-derived exosomal microRNA-30a-5p reduces the resistance of ovarian cancer cells to DDP8
miR-1202 acts as anti-oncomiR in myeloid leukaemia by down-modulating GATA-1 S expression8
Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments8
Myeloid-derived suppressor cells and the pathogenesis of human immunodeficiency virus infection8
Analysis of the phosphoproteome of CK2 α (–/–)α′ C2C12 myoblasts compared to the wild-type cells8
Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections8
Cancer cells’ chamber of secrets: the link between micronuclei, chromothripsis and malignancy8
Mechanotransduction as a major driver of cell behaviour: mechanisms, and relevance to cell organization and future research8
Modulating streptococcal phenotypes using signal peptide analogues8
Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis8
Axon demyelination and degeneration in a zebrafish spastizin model of hereditary spastic paraplegia8
Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cells8
An MD-2-related lipid-recognition protein is required for insect reproduction and integument development7
Expression of concern: ‘Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p’ (2020), by Cui Z et al.7
ARNO is recruited by the neuronal adaptor FE65 to potentiate ARF6-mediated neurite outgrowth7
High-resolution analysis of individual Drosophila melanogaster larvae uncovers individual variability in locomotion and its neurogenetic modulation7
The immune deficiency and c-Jun N-terminal kinase pathways drive the functional integration of the immune and circulatory systems of mosquitoes7
The role of endothelial-derived factors in neural tube development: implications for organoid models7
A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells7
Improvement of the antibody-dependent respiratory burst assay for assessing protective immune responses to malaria7
Characterization of microglia behaviour in healthy and pathological conditions with image analysis tools7
Functional disruption of oxytocin projections participates atypical social and anxiety-like behaviours in BTBR mouse model of autism7
Plasmodium LCCL domain-containing modular proteins have their origins in the ancestral alveolate7
Systemic analyses show that the biosynthesis and spatial distribution of fatty acids, triglycerides and lipids differed in male and female mice and humans7
Reinventing the spermatheca: unveiling a novel sperm storage organ in Epilachninae ladybirds7
Simple, streamlined, cost-effective cDNA synthesis method from cell cultures7
The cytosolic form of dual localized BolA family protein Bol3 is important for adaptation to iron starvation in Aspergillus fumigatus7
Correction to: ‘The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence’ (2016), by Burla et al.7
The potential roles of retinoids in combating drug resistance in cancer: implications of ATP-binding cassette (ABC) transporters7
Quantitative single molecule analysis of podoplanin clustering in fibroblastic reticular cells uncovers CD44 function7
Gene duplication is the primary driver of intraspecific genomic divergence in coral algal symbionts6
IFNγ-dependent silencing of TFF1 during Helicobacter pylori infection6
Single-molecule tracking (SMT) and localization of SRF and MRTF transcription factors during neuronal stimulation and differentiation6
Proximal partners of the organellar N-terminal acetyltransferase NAA60: insights into Golgi structure and transmembrane protein topology6
Structure and molecular basis of spermatid elongation in theDrosophilatestis6
Microsporidian parasite impairs colony fitness in bumblebees6
Patterning principles of morphogen gradients6
Haploidy-linked cell proliferation defects limit larval growth in zebrafish6
Regional random mutagenesis driven by multiple sgRNAs and diverse on-target genome editing events to identify functionally important elements in non-coding regions6
The histone deacetylase inhibitor Scriptaid targets G-quadruplexes6
Evaluating the efficacy of protein quantification methods on membrane proteins6
The fission yeast NDR kinase Orb6 and its signalling pathway MOR regulate cytoplasmic microtubule organization during the cell cycle6
Unravelling the mystery of female meiotic drive: where we are6
Mitochondrial-derived gene expression in hibernation: tissue-specific responses in the thirteen-lined ground squirrel6
Unveiling the functional nature of retrogenes in dinoflagellates6
Mechanisms driving spatial distribution of residents in colony biofilms: an interdisciplinary perspective6
In vivoassessment of mechanical properties during axolotl development and regeneration using confocal Brillouin microscopy6
The CoREST complex regulates multiple histone modifications temporal-specifically in clock neurons6
Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons6
A novel FAM83G variant from palmoplantar keratoderma patient disrupts WNT signalling via loss of FAM83G-CK1α interaction6
Selective loss of ATP carriers in favour of SLC25A43 orthologues in metamonad mitochondria adapted to anaerobiosis6
Pattern recognition in living cells through the lens of machine learning6
Plasmodium berghei leucine-rich repeat protein 1 downregulates protein phosphatase 1 activity and is required for efficient oocyst development6
The nature of ‘jaws’: a new predatory representative of Provora and the ultrastructure of nibbling protists6
Genome organization and evolution of a eukaryotic nicotinate co-inducible pathway6
The human HELQ helicase and XRN2 exoribonuclease cooperate in R-loop resolution6
A high-throughput protein tagging toolkit that retains endogenous untranslated regions for studying gene regulation in kinetoplastids5
PK1 from Drosophila obscurin is an inactive pseudokinase with scaffolding properties5
POU-M2 promotes juvenile hormone biosynthesis by directly activating the transcription of juvenile hormone synthetic enzyme genes in Bombyx mori5
Restricting a single amino acid cross-protects Drosophila melanogaster from nicotine poisoning through mTORC1 and GCN2 signalling5
NFIL3 contributes to cytotoxic T lymphocyte-mediated killing5
AMPK phosphorylates NAMPT to regulate NAD + homeostasis under ionizing radiation5
Cell autonomous and non-autonomous consequences of deviations in translation machinery on organism growth and the connecting signalling pathways5
Cell cycle visualization tools to study cardiomyocyte proliferation in real-time5
Cell wall deficiency as an escape mechanism from phage infection5
ATP-dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming5
Ovothiol ensures the correct developmental programme of the sea urchin Paracentrotus lividus embryo5
MYC regulates metabolism through vesicular transfer of glycolytic kinases5
Multi-epitope vaccine candidates based on mycobacterial membrane protein large (MmpL) proteins against Mycobacterium ulcerans5
Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation5
Greatwall-Endos-PP2A/B55 Twins network regulates translation and stability of maternal transcripts in the Drosophila oocyte-to-embryo 5
ELMOD3-Rab1A-Flotillin2 cascade regulates lumen formation via vesicle trafficking inCionanotochord5
Live imaging YAP signalling in mouse embryo development5
Brain amino acid sensing for organismal amino acid homeostasis5
tRNA copy number and codon usage in the sea cucumber genome provide insights into adaptive translation for saponin biosynthesis5
Ultrastructure expansion microscopy in Trypanosoma brucei5
Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes5
Sperm-borne mRNAs: potential roles in zygote genome activation and epigenetic inheritance5
Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-25
Gut microbiota diversity affects fish behaviour and is influenced by host genetics and early rearing conditions5
Mitochondrial biology and dysfunction in secondary mitochondrial disease5
Evolutionary mode for the functional preservation of fast-evolving Drosophila telomere capping proteins5
Mutant SPART causes defects in mitochondrial protein import and bioenergetics reversed by Coenzyme Q5
Controlling the topology of mammalian mitochondrial DNA5
Bacterial division ring stabilizing ZapA versus destabilizing SlmA modulate FtsZ switching between biomolecular condensates and polymers5
Molecular and morphological approach to study the innexin gap junctions in Rhynchosciara americana5
Correction to ‘Global pleiotropic effects in adaptively evolved Escherichia coli lacking CRP reveal molecular mechanisms that define the growth physiology’5
The information overload, immunology and their relationship to world health5
Recent advances in understanding of enterobacterial common antigen synthesis and regulation5
Opium alkaloids, biosynthesis, pharmacology and association with cancer occurrence4
The functional diversity of the POUV-class proteins across vertebrates4
Metabolic control of epigenetic rearrangements in B cell pathophysiology4
Expansion microscopy facilitates quantitative super-resolution studies of cytoskeletal structures in kinetoplastid parasites4
HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta4
Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature4
Nucleotide-free structures of KIF20A illuminate atypical mechanochemistry in this kinesin-64
Single amino acid substitutions in hydrophobic cores at a head-coiled coil junction region of cohesin facilitate its release of DNA during anaphase4
Skewed distribution of spines is independent of presynaptic transmitter release and synaptic plasticity, and emerges early during adult neurogenesis4
Head transcriptome profiling of glossiphoniid leech ( Helobdella austinensis ) reveals clues about proboscis development4
Molecular mechanisms of developmental pathways in neurological disorders: a pharmacological and therapeutic review4
Krüppel-homologue 1regulates the development ofTuta absolutaand its cascade regulation pattern in the juvenile hormone signalling pathway4
Identification of PP2A-B55 targets uncovers regulation of emerin during nuclear envelope reassembly inDrosophila4
A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation4
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