Open Biology

Papers
(The median citation count of Open Biology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Into the second decade137
Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours103
Decoding life's inner workings: advances in quantitative bioimaging89
A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis88
Cosegregation of asymmetric features during cell division70
Limitations of sequence dissimilarity as a predictor of prokaryotic lineage67
Retraction: ‘HOXD-AS1 confers cisplatin resistance in gastric cancer through epigenetically silencing PDCD4 via recruiting EZH2’ (2019), by Ye et al.67
MYH7 R453C induced cardiac remodelling via activating TGF-β/Smad2/3, ERK1/2 and Nox4/ROS/NF-κB signalling pathways64
Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod57
Comparative mitogenomic analysis and phylogeny of Veneridae with doubly uniparental inheritance56
Nutrient-sensitive protein O-GlcNAcylation shapes daily biological rhythms51
RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication49
Visualization of sympathetic neural innervation in human white adipose tissue44
Correction to: ‘Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae ’ (2024), 42
Intrinsically disordered proteins: modes of binding with emphasis on disordered domains42
Risk factors for severe COVID-19 disease increase SARS-CoV-2 infectivity of endothelial cells and pericytes40
A new view of axon growth and guidance grounded in the stochastic dynamics of actin networks38
Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p2738
Integrative analysis of genomic and transcriptomic alterations of AGR2 and AGR3 in cancer38
Transiently restricting individual amino acids protects Drosophila melanogaster against multiple stressors36
Essential roles of the nucleolus during early embryonic development: a regulatory hub for chromatin organization35
The tumour suppressor brain tumour (Brat) regulates linker histone dBigH1 expression in the Drosophila female germline and the early embryo35
Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and its impact on neuron biology34
Retraction: ‘Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial-mesenchymal transition by regulating HIF-1α via miR-138’33
From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs33
Every good biologist deserves favour33
Complement receptor 3-dependent engagement by Candida glabrata β-glucan modulates dendritic cells to induce regulatory T-cell expansion32
The first genetic engineered system for ovothiol biosynthesis in diatoms reveals a mitochondrial localization for the sulfoxide synthase OvoA32
SID-2 is a conserved extracellular vesicle protein that is not associated with environmental RNAi in parasitic nematodes31
Min oscillations in bacteria as real-time reporter of environmental challenges at the single-cell level31
Pleiotropic effects on proliferation and mineralization of primary human adipose tissue-derived stromal cells induced by simvastatin30
Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?30
NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors30
Identification and characterization of host miRNAs that target the mouse mammary tumour virus (MMTV) genome29
Arabidopsis thaliana endonuclease V is a ribonuclease specific for inosine-containing single-stranded RNA29
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system28
SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation28
Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae28
A comparative analysis of parechovirus protein structures with other picornaviruses27
Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism26
Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics26
Footprints in the Sno: investigating the cellular and molecular mechanisms of SNORD11626
The role of α-sheet structure in amyloidogenesis: characterization and implications26
Microanatomical and secretory characterization of the salivary gland of the Rhodnius prolixus (Hemiptera, Reduviidae, Triatominae), a main vector of Chagas disease25
Retraction: ‘Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p’ (2020), by Cui et al.25
A fast-growing dengue virus mutant reveals a dual role of STING in response to infection25
Au naturale: use of biologically derived cyclic di-nucleotides for cancer immunotherapy24
Pck2 association with the plasma membrane and efficient response of the cell integrity pathway require regulation of PI4P homeostasis by exomer24
Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response24
In vitro reconstitution of substrate S-acylation by the zDHHC family of protein acyltransferases24
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation23
Correction to ‘Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments’ (2022) by Kellom et al .23
The genetic basis and potential molecular mechanism of yellow-albino northern snakehead (Channa argus)22
Development of the mammalian cortical hem and its derivatives: the choroid plexus, Cajal–Retzius cells and hippocampus22
Genome-wide identification of ATP-binding cassette transporter B subfamily, focusing on its structure, evolution and rearrangement in ciliates22
Reversible bacteriophage resistance by shedding the bacterial cell wall21
Learning-induced remodelling of inhibitory synapses in the motor cortex21
Neuronal signalling of zinc: from detection and modulation to function21
A circle of life: platelet and megakaryocyte cytoskeleton dynamics in health and disease21
Stepwise order in protein complex assembly: approaches and emerging themes20
Polycomb-mediated transgenerational epigenetic inheritance of Drosophila eye colour is independent of small RNAs19
C-terminal glycosylation of type IX secretion system cargo proteins in Prevotella intermedia with both short and long secretion signals19
Proteomic comparison of the organic matrices from parietal and base plates of the acorn barnacle Amphibalanus amphitrite19
The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint19
Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation19
Multifunctional roles of Sec13 paralogues in the euglenozoan Trypanosoma brucei19
Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria18
GNL3 is an evolutionarily conserved stem cell gene influencing cell proliferation, animal growth and regeneration in the hydrozoan Hydractinia18
miR-155-3p: processing by-product or rising star in immunity and cancer?18
Structural basis for the coiled-coil architecture of human CtIP18
Light-induced reversible reorganizations in closed Type II reaction centre complexes: physiological roles and physical mechanisms18
Whole organism and tissue-specific analysis of pexophagy in Drosophila17
Expression of concern: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui Y et al.17
Retraction: ‘MALAT1 promotes gastric adenocarcinoma through the MALAT1/miR-181a-5p/AKT3 axis’ (2019), by Lu et al.16
Aurodox inhibits type III secretion in multiple Gram-negative pathogens16
The supernumerary B chromosome of maize: drive and genomic conflict16
SIRT7: a sentinel of genome stability16
Temperature activated transient receptor potential ion channels from Antarctic fishes16
Exploring the midgut physiology of the non-haematophagous mosquito Toxorhynchites theobaldi15
Appendage regeneration is context dependent at the cellular level15
Identification of the modulatory Ca 2+ -binding sites of acid-sensing ion channel 1a15
Terminal regions of a protein are a hotspot for low complexity regions and selection15
Retraction: ‘Long non-coding RNA LINC00467 regulates hepatocellular carcinoma progression by modulating miR-9-5p/PPARA expression’ (2019), by Cai et al.15
The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex15
Decoding frontotemporal and cell-type-specific vulnerabilities to neuropsychiatric disorders and psychoactive drugs14
Plant NLR immunity activation and execution: a biochemical perspective14
Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis14
Spatial transcriptomes and microbiota reveal immune mechanism that respond to pathogen infection in the posterior intestine ofSebastes schlegelii14
Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades13
Mapping combinatorial expression of non-clustered protocadherins in the developing brain identifies novel PCDH19-mediated cell adhesion properties13
A simple inland culture system provides insights into ascidian post-embryonic developmental physiology13
Polo-like kinase and Aurora B kinase phosphorylate and cooperate with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei13
Effective training of nanopore callers for epigenetic marks with limited labelled data13
MicroRNAs: master regulators in host–parasitic protist interactions13
Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction13
PACS deficiency disrupts Golgi architecture and causes cytokinesis failures and seizure-like phenotype in Drosophila melanogaster13
Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells13
Centromere function in asymmetric cell division in Drosophila female and male germline stem cells13
Daughter centrioles assemble preferentially towards the nuclear envelope in Drosophila syncytial embryos13
Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS12
Evolution and assembly of Anopheles aquasalis 's immune genes: primary malaria vector of coastal Central and South America and the Caribbean Islands12
Exploring differential exon usage via short- and long-read RNA sequencing strategies12
Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders12
Time-optimized feeding is beneficial without enforced fasting12
Pseudogenization of NK3 homeobox 2 ( Nkx3.2 ) in monotremes provides insight into unique gastric anatomy and physiology12
Capturing crop adaptation to abiotic stress using image-based technologies12
Lysosomal positioning diseases: beyond substrate storage12
Insights into the bioluminescence systems of three sea pens (Cnidaria: Anthozoa): from de novo transcriptome analyses to biochemical assays12
Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m 7 G-cap-dependent translation at the 8- to 16-cell transition12
Proposed three-phenylalanine motif involved in magnetoreception signalling of an Actinopterygii protein expressed in mammalian cells11
The proline-rich antimicrobial peptide B7-005: low bacterial resistance, safe for human cells and effective in zebrafish embryo bacteraemia model11
Iron-sulfur flavoenzymes: the added value of making the most ancient redox cofactors and the versatile flavins work together11
Aspirin and cancer: biological mechanisms and clinical outcomes11
Single-cell expression predicts neuron-specific protein homeostasis networks11
Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease11
2024: The quest continues11
Plum modulates Myoglianin and regulates synaptic function in D. melanogaster11
Pigment-dispersing factor is present in circadian clock neurons of pea aphids and may mediate photoperiodic signalling to insulin-producing cells11
Phosphorylation of ‘SDT-like’ motifs in ATRX mediates its interaction with the MRN complex and is important for ALT pathway suppression10
TRIM family proteins: roles in proteostasis and neurodegenerative diseases10
High-throughput functional analysis provides novel insight into type VII secretion in Staphylococcus aureus10
Retraction: ‘Involvement of miR-4262 in paclitaxel resistance through the regulation of PTEN in non-small cell lung cancer’ (2019), by Sun et al.10
The intrinsically disorderly story of Ki-6710
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH10
The gender-specific impact of starvation on mitotypes diversity in adults of Drosophila melanogaster10
Distinct molecular profile of the chick organizer as a stem zone during axial elongation10
Expression and function of PDGF-C in development and stem cells10
Examination of gammarid transcriptomes reveals a widespread occurrence of key metabolic genes from epibiont bdelloid rotifers in freshwater species10
Modern and prebiotic amino acids support distinct structural profiles in proteins10
Retraction: ‘TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin’ (2016), by Wang et al.10
Prebiotic chemistry: a review of nucleoside phosphorylation and polymerization10
Mapping molecular complexes with super-resolution microscopy and single-particle analysis10
Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells10
Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin10
Repo-Man/protein phosphatase 1 SUMOylation mediates binding to lamin A and serine 22 dephosphorylation10
The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body10
Cooperative motility, force generation and mechanosensing in a foraging non-photosynthetic diatom10
Brain and testis: more alike than previously thought?10
Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections10
Phylogenomic diversity of archigregarine apicomplexans9
The potential roles of retinoids in combating drug resistance in cancer: implications of ATP-binding cassette (ABC) transporters9
miR-1202 acts as anti-oncomiR in myeloid leukaemia by down-modulating GATA-1 S expression9
The post-translational modification O-GlcNAc is a sensor and regulator of metabolism9
Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis9
Analysis of the phosphoproteome of CK2 α (–/–)α′ C2C12 myoblasts compared to the wild-type cells9
Modulating streptococcal phenotypes using signal peptide analogues9
Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila9
Efficient CRISPR/Cas9-mediated gene disruption in the tetraploid protist Giardia intestinalis9
ARNO is recruited by the neuronal adaptor FE65 to potentiate ARF6-mediated neurite outgrowth9
Role of amylopectin synthesis in Toxoplasma gondii and its implication in vaccine development against toxoplasmosis9
Intense light unleashes male–male courtship behaviour in wild-type Drosophila8
A diversified and segregated mRNA spliced-leader system in the parasitic Perkinsozoa8
Therapeutic potential of astaxanthin and superoxide dismutase in Alzheimer's disease8
Multiple factors contribute to female dominance in migratory bioflows8
Expression of concern: DDP-resistant ovarian cancer cells-derived exosomal microRNA-30a-5p reduces the resistance of ovarian cancer cells to DDP8
Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments8
Quantifying the large-scale chromosome structural dynamics during the mitosis-to-G1 phase transition of cell cycle8
Mechanotransduction as a major driver of cell behaviour: mechanisms, and relevance to cell organization and future research8
Axon demyelination and degeneration in a zebrafish spastizin model of hereditary spastic paraplegia8
Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cells8
Myeloid-derived suppressor cells and the pathogenesis of human immunodeficiency virus infection8
Expression of concern: ‘TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin’ (2016), by Wang N et al.8
Improvement of the antibody-dependent respiratory burst assay for assessing protective immune responses to malaria8
The cytosolic form of dual localized BolA family protein Bol3 is important for adaptation to iron starvation in Aspergillus fumigatus7
Plasmodium LCCL domain-containing modular proteins have their origins in the ancestral alveolate7
The three-component helicase/primase complex of herpes simplex virus-17
Quantitative single molecule analysis of podoplanin clustering in fibroblastic reticular cells uncovers CD44 function7
Regional random mutagenesis driven by multiple sgRNAs and diverse on-target genome editing events to identify functionally important elements in non-coding regions7
Expression of concern: ‘Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p’ (2020), by Cui Z et al.7
Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons7
The CoREST complex regulates multiple histone modifications temporal-specifically in clock neurons7
High-resolution analysis of individual Drosophila melanogaster larvae uncovers individual variability in locomotion and its neurogenetic modulation7
The human HELQ helicase and XRN2 exoribonuclease cooperate in R-loop resolution7
Proximal partners of the organellar N-terminal acetyltransferase NAA60: insights into Golgi structure and transmembrane protein topology7
Simple, streamlined, cost-effective cDNA synthesis method from cell cultures7
Evaluating the efficacy of protein quantification methods on membrane proteins7
A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells7
Genome organization and evolution of a eukaryotic nicotinate co-inducible pathway7
The histone deacetylase inhibitor Scriptaid targets G-quadruplexes7
A novel FAM83G variant from palmoplantar keratoderma patient disrupts WNT signalling via loss of FAM83G-CK1α interaction7
Correction to: ‘The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence’ (2016), by Burla et al.7
An MD-2-related lipid-recognition protein is required for insect reproduction and integument development7
Characterization of microglia behaviour in healthy and pathological conditions with image analysis tools7
IFNγ-dependent silencing of TFF1 during Helicobacter pylori infection7
The immune deficiency and c-Jun N-terminal kinase pathways drive the functional integration of the immune and circulatory systems of mosquitoes6
Haploidy-linked cell proliferation defects limit larval growth in zebrafish6
Single-molecule tracking (SMT) and localization of SRF and MRTF transcription factors during neuronal stimulation and differentiation6
Microsporidian parasite impairs colony fitness in bumblebees6
Unveiling the functional nature of retrogenes in dinoflagellates6
A high-throughput protein tagging toolkit that retains endogenous untranslated regions for studying gene regulation in kinetoplastids6
Multi-epitope vaccine candidates based on mycobacterial membrane protein large (MmpL) proteins against Mycobacterium ulcerans6
The fission yeast NDR kinase Orb6 and its signalling pathway MOR regulate cytoplasmic microtubule organization during the cell cycle6
Gene duplication is the primary driver of intraspecific genomic divergence in coral algal symbionts6
Patterning principles of morphogen gradients6
POU-M2 promotes juvenile hormone biosynthesis by directly activating the transcription of juvenile hormone synthetic enzyme genes in Bombyx mori6
Mitochondrial biology and dysfunction in secondary mitochondrial disease6
Unravelling the mystery of female meiotic drive: where we are6
Spatial activation of ezrin by epidermal growth factor receptor and focal adhesion kinase co-ordinates epithelial cell migration6
DDX21 is a p38-MAPK-sensitive nucleolar protein necessary for mouse preimplantation embryo development and cell-fate specification6
The nature of ‘jaws’: a new predatory representative of Provora and the ultrastructure of nibbling protists6
In vivoassessment of mechanical properties during axolotl development and regeneration using confocal Brillouin microscopy6
Plasmodium berghei leucine-rich repeat protein 1 downregulates protein phosphatase 1 activity and is required for efficient oocyst development6
Structure and molecular basis of spermatid elongation in theDrosophilatestis6
Mechanisms driving spatial distribution of residents in colony biofilms: an interdisciplinary perspective6
Evolutionary mode for the functional preservation of fast-evolving Drosophila telomere capping proteins6
AMPK phosphorylates NAMPT to regulate NAD + homeostasis under ionizing radiation5
Mutant SPART causes defects in mitochondrial protein import and bioenergetics reversed by Coenzyme Q5
Malaria, COVID-19 and angiotensin-converting enzyme 2: what does the available population data say?5
tRNA copy number and codon usage in the sea cucumber genome provide insights into adaptive translation for saponin biosynthesis5
Sperm-borne mRNAs: potential roles in zygote genome activation and epigenetic inheritance5
Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-25
Ultrastructure expansion microscopy in Trypanosoma brucei5
Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation5
From intestine to beyond: Salmonella entry factors display distinct transcription pattern upon infection in murine models5
Cell wall deficiency as an escape mechanism from phage infection5
Separated parabiont reveals the fate and lifespan of peripheral-derived immune cells in normal and ischaemia-induced injured kidneys5
A transgenic zebrafish forin vivovisualization of cilia5
Correction to ‘Global pleiotropic effects in adaptively evolved Escherichia coli lacking CRP reveal molecular mechanisms that define the growth physiology’5
Cell cycle visualization tools to study cardiomyocyte proliferation in real-time5
Primary cilia and lipid raft dynamics5
Restricting a single amino acid cross-protects Drosophila melanogaster from nicotine poisoning through mTORC1 and GCN2 signalling5
ATP-dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming5
Gut microbiota diversity affects fish behaviour and is influenced by host genetics and early rearing conditions5
Ovothiol ensures the correct developmental programme of the sea urchin Paracentrotus lividus embryo5
Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes5
NFIL3 contributes to cytotoxic T lymphocyte-mediated killing5
CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 35
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex5
Live-cell microscopy or fluorescence anisotropy with budded baculoviruses—which way to go with measuring ligand binding to M 4 muscarinic receptors?5
Cell autonomous and non-autonomous consequences of deviations in translation machinery on organism growth and the connecting signalling pathways5
Bacterial division ring stabilizing ZapA versus destabilizing SlmA modulate FtsZ switching between biomolecular condensates and polymers5
Molecular and morphological approach to study the innexin gap junctions in Rhynchosciara americana5
Greatwall-Endos-PP2A/B55 Twins network regulates translation and stability of maternal transcripts in the Drosophila oocyte-to-embryo 5
PK1 from Drosophila obscurin is an inactive pseudokinase with scaffolding properties5
MYC regulates metabolism through vesicular transfer of glycolytic kinases5
ELMOD3-Rab1A-Flotillin2 cascade regulates lumen formation via vesicle trafficking inCionanotochord5
Live imaging YAP signalling in mouse embryo development5
Retraction: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui et al.5
Controlling the topology of mammalian mitochondrial DNA5
Mathematical model of RNA-directed DNA methylation predicts tuning of negative feedback required for stable maintenance5
Opium alkaloids, biosynthesis, pharmacology and association with cancer occurrence4
Single amino acid substitutions in hydrophobic cores at a head-coiled coil junction region of cohesin facilitate its release of DNA during anaphase4
Skewed distribution of spines is independent of presynaptic transmitter release and synaptic plasticity, and emerges early during adult neurogenesis4
Krüppel-homologue 1regulates the development ofTuta absolutaand its cascade regulation pattern in the juvenile hormone signalling pathway4
Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature4
Expansion microscopy facilitates quantitative super-resolution studies of cytoskeletal structures in kinetoplastid parasites4
Identification of PP2A-B55 targets uncovers regulation of emerin during nuclear envelope reassembly inDrosophila4
Evolutionary analysis of p38 stress-activated kinases in unicellular relatives of animals suggests an ancestral function in osmotic stress4
Deciphering respiratory viral infections by harnessing organ-on-chip technology to explore the gut–lung axis4
DNA fragility at the KMT2A / MLL locus: insights from old and new technologies4
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