Open Biology

Papers
(The median citation count of Open Biology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod133
A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis101
MYH7 R453C induced cardiac remodelling via activating TGF-β/Smad2/3, ERK1/2 and Nox4/ROS/NF-κB signalling pathways99
Cosegregation of asymmetric features during cell division77
Nutrient-sensitive protein O-GlcNAcylation shapes daily biological rhythms73
Correction to: ‘Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae ’ (2024), 69
Visualization of sympathetic neural innervation in human white adipose tissue63
Into the second decade48
Retraction: ‘HOXD-AS1 confers cisplatin resistance in gastric cancer through epigenetically silencing PDCD4 via recruiting EZH2’ (2019), by Ye et al.47
Decoding life's inner workings: advances in quantitative bioimaging47
Comparative mitogenomic analysis and phylogeny of Veneridae with doubly uniparental inheritance44
Limitations of sequence dissimilarity as a predictor of prokaryotic lineage43
Intrinsically disordered proteins: modes of binding with emphasis on disordered domains41
RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication41
Oxidized phospholipid damage signals as modulators of immunity40
Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours39
Risk factors for severe COVID-19 disease increase SARS-CoV-2 infectivity of endothelial cells and pericytes38
Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?37
Integrative analysis of genomic and transcriptomic alterations of AGR2 and AGR3 in cancer36
SID-2 is a conserved extracellular vesicle protein that is not associated with environmental RNAi in parasitic nematodes36
From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs36
Pleiotropic effects on proliferation and mineralization of primary human adipose tissue-derived stromal cells induced by simvastatin35
Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and its impact on neuron biology35
Transiently restricting individual amino acids protects Drosophila melanogaster against multiple stressors34
SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation33
Identification and characterization of host miRNAs that target the mouse mammary tumour virus (MMTV) genome32
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system32
NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors31
Complement receptor 3-dependent engagement by Candida glabrata β-glucan modulates dendritic cells to induce regulatory T-cell expansion31
The first genetic engineered system for ovothiol biosynthesis in diatoms reveals a mitochondrial localization for the sulfoxide synthase OvoA31
Essential roles of the nucleolus during early embryonic development: a regulatory hub for chromatin organization30
Every good biologist deserves favour30
Min oscillations in bacteria as real-time reporter of environmental challenges at the single-cell level30
A new view of axon growth and guidance grounded in the stochastic dynamics of actin networks29
Retraction: ‘Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial-mesenchymal transition by regulating HIF-1α via miR-138’29
Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p2728
Arabidopsis thaliana endonuclease V is a ribonuclease specific for inosine-containing single-stranded RNA28
Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response26
In vitro reconstitution of substrate S-acylation by the zDHHC family of protein acyltransferases26
A fast-growing dengue virus mutant reveals a dual role of STING in response to infection26
Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae25
Footprints in the Sno: investigating the cellular and molecular mechanisms of SNORD11625
Pck2 association with the plasma membrane and efficient response of the cell integrity pathway require regulation of PI4P homeostasis by exomer24
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation24
Retraction: ‘Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p’ (2020), by Cui et al.24
The genetic basis and potential molecular mechanism of yellow-albino northern snakehead (Channa argus)24
Au naturale: use of biologically derived cyclic di-nucleotides for cancer immunotherapy24
Correction to ‘Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments’ (2022) by Kellom et al .23
The role of α-sheet structure in amyloidogenesis: characterization and implications23
Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism23
Interplay between circadian rhythm, ageing and neurodegenerative disorder22
Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics22
The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint21
Multifunctional roles of Sec13 paralogues in the euglenozoan Trypanosoma brucei20
Proteomic comparison of the organic matrices from parietal and base plates of the acorn barnacle Amphibalanus amphitrite20
Reversible bacteriophage resistance by shedding the bacterial cell wall20
Learning-induced remodelling of inhibitory synapses in the motor cortex19
Stepwise order in protein complex assembly: approaches and emerging themes19
Light-induced reversible reorganizations in closed Type II reaction centre complexes: physiological roles and physical mechanisms19
Polycomb-mediated transgenerational epigenetic inheritance of Drosophila eye colour is independent of small RNAs19
C-terminal glycosylation of type IX secretion system cargo proteins in Prevotella intermedia with both short and long secretion signals19
A circle of life: platelet and megakaryocyte cytoskeleton dynamics in health and disease18
Genome-wide identification of ATP-binding cassette transporter B subfamily, focusing on its structure, evolution and rearrangement in ciliates18
miR-155-3p: processing by-product or rising star in immunity and cancer?18
Neuronal signalling of zinc: from detection and modulation to function18
Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria18
Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation17
Temperature activated transient receptor potential ion channels from Antarctic fishes17
Long-read RNA-sequencing reveals transcript-specific regulation in human-derived cortical neurons17
Aurodox inhibits type III secretion in multiple Gram-negative pathogens16
The supernumerary B chromosome of maize: drive and genomic conflict16
Whole organism and tissue-specific analysis of pexophagy in Drosophila16
Expression of concern: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui Y et al.16
Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells15
Spatial transcriptomes and microbiota reveal immune mechanism that respond to pathogen infection in the posterior intestine ofSebastes schlegelii15
The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex15
GNL3 is an evolutionarily conserved stem cell gene influencing cell proliferation, animal growth and regeneration in the hydrozoan Hydractinia15
Decoding frontotemporal and cell-type-specific vulnerabilities to neuropsychiatric disorders and psychoactive drugs14
Retraction: ‘Long non-coding RNA LINC00467 regulates hepatocellular carcinoma progression by modulating miR-9-5p/PPARA expression’ (2019), by Cai et al.14
Effective training of nanopore callers for epigenetic marks with limited labelled data14
MicroRNAs: master regulators in host–parasitic protist interactions14
Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis14
Identification of the modulatory Ca 2+ -binding sites of acid-sensing ion channel 1a14
Exploring the midgut physiology of the non-haematophagous mosquito Toxorhynchites theobaldi14
Unravelling axonal transcriptional landscapes: insights from induced pluripotent stem cell-derived cortical neurons and implications for motor neuron degeneration14
Retraction: ‘MALAT1 promotes gastric adenocarcinoma through the MALAT1/miR-181a-5p/AKT3 axis’ (2019), by Lu et al.14
Exploring differential exon usage via short- and long-read RNA sequencing strategies13
Plant NLR immunity activation and execution: a biochemical perspective13
Mapping combinatorial expression of non-clustered protocadherins in the developing brain identifies novel PCDH19-mediated cell adhesion properties13
Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m 7 G-cap-dependent translation at the 8- to 16-cell transition13
The challenge of measuring mosquito flight performance: going beyond sterile insect technique and into transgenic and gene drive-based approaches13
GLP-1/GLP-1R axis: from metabolism (obesity and T2DM) to immunity13
Terminal regions of a protein are a hotspot for low complexity regions and selection13
Centromere function in asymmetric cell division in Drosophila female and male germline stem cells13
PIEZO1 variant implications for biological understanding and human health13
Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction13
Daughter centrioles assemble preferentially towards the nuclear envelope in Drosophila syncytial embryos13
Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades13
Capturing crop adaptation to abiotic stress using image-based technologies12
PACS deficiency disrupts Golgi architecture and causes cytokinesis failures and seizure-like phenotype in Drosophila melanogaster12
Phosphorylation of ‘SDT-like’ motifs in ATRX mediates its interaction with the MRN complex and is important for ALT pathway suppression12
Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development12
Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS12
Pseudogenization of NK3 homeobox 2 ( Nkx3.2 ) in monotremes provides insight into unique gastric anatomy and physiology12
Lysosomal positioning diseases: beyond substrate storage12
The proline-rich antimicrobial peptide B7-005: low bacterial resistance, safe for human cells and effective in zebrafish embryo bacteraemia model12
Insights into the bioluminescence systems of three sea pens (Cnidaria: Anthozoa): from de novo transcriptome analyses to biochemical assays12
A simple inland culture system provides insights into ascidian post-embryonic developmental physiology12
Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders12
Polo-like kinase and Aurora B kinase phosphorylate and cooperate with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei12
Expression and function of PDGF-C in development and stem cells11
Evolution and assembly of Anopheles aquasalis 's immune genes: primary malaria vector of coastal Central and South America and the Caribbean Islands11
TRIM family proteins: roles in proteostasis and neurodegenerative diseases11
2024: The quest continues11
Plum modulates Myoglianin and regulates synaptic function in D. melanogaster11
Aspirin and cancer: biological mechanisms and clinical outcomes11
Single-cell expression predicts neuron-specific protein homeostasis networks11
Time-optimized feeding is beneficial without enforced fasting11
Pigment-dispersing factor is present in circadian clock neurons of pea aphids and may mediate photoperiodic signalling to insulin-producing cells11
Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin10
Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease10
High-throughput functional analysis provides novel insight into type VII secretion in Staphylococcus aureus10
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH10
Mapping molecular complexes with super-resolution microscopy and single-particle analysis10
Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells10
Examination of gammarid transcriptomes reveals a widespread occurrence of key metabolic genes from epibiont bdelloid rotifers in freshwater species10
Phylogenomic diversity of archigregarine apicomplexans10
Cooperative motility, force generation and mechanosensing in a foraging non-photosynthetic diatom10
The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body10
Retraction: ‘TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin’ (2016), by Wang et al.10
Proposed three-phenylalanine motif involved in magnetoreception signalling of an Actinopterygii protein expressed in mammalian cells10
Distinct molecular profile of the chick organizer as a stem zone during axial elongation10
Retraction: ‘Involvement of miR-4262 in paclitaxel resistance through the regulation of PTEN in non-small cell lung cancer’ (2019), by Sun et al.10
The gender-specific impact of starvation on mitotypes diversity in adults of Drosophila melanogaster10
Repo-Man/protein phosphatase 1 SUMOylation mediates binding to lamin A and serine 22 dephosphorylation9
Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections9
Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments9
Prebiotic chemistry: a review of nucleoside phosphorylation and polymerization9
Modern and prebiotic amino acids support distinct structural profiles in proteins9
Biochemistry and physiology of voltage-gated calcium channel trafficking: a target for gabapentinoid drugs9
The intrinsically disorderly story of Ki-679
Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila9
The post-translational modification O-GlcNAc is a sensor and regulator of metabolism9
Cancer cells’ chamber of secrets: the link between micronuclei, chromothripsis and malignancy9
ARNO is recruited by the neuronal adaptor FE65 to potentiate ARF6-mediated neurite outgrowth8
O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control8
Myeloid-derived suppressor cells and the pathogenesis of human immunodeficiency virus infection8
Multiple factors contribute to female dominance in migratory bioflows8
Intense light unleashes male–male courtship behaviour in wild-type Drosophila8
Modulating streptococcal phenotypes using signal peptide analogues8
Expression of concern: DDP-resistant ovarian cancer cells-derived exosomal microRNA-30a-5p reduces the resistance of ovarian cancer cells to DDP8
Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis8
An MD-2-related lipid-recognition protein is required for insect reproduction and integument development8
Analysis of the phosphoproteome of CK2 α (–/–)α′ C2C12 myoblasts compared to the wild-type cells8
Efficient CRISPR/Cas9-mediated gene disruption in the tetraploid protist Giardia intestinalis8
miR-1202 acts as anti-oncomiR in myeloid leukaemia by down-modulating GATA-1 S expression8
Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cells8
Mechanotransduction as a major driver of cell behaviour: mechanisms, and relevance to cell organization and future research8
A diversified and segregated mRNA spliced-leader system in the parasitic Perkinsozoa8
A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells8
Axon demyelination and degeneration in a zebrafish spastizin model of hereditary spastic paraplegia8
Expression of concern: ‘TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin’ (2016), by Wang N et al.8
The potential roles of retinoids in combating drug resistance in cancer: implications of ATP-binding cassette (ABC) transporters8
Quantifying the large-scale chromosome structural dynamics during the mitosis-to-G1 phase transition of cell cycle8
Quantitative single molecule analysis of podoplanin clustering in fibroblastic reticular cells uncovers CD44 function7
Plasmodium LCCL domain-containing modular proteins have their origins in the ancestral alveolate7
Proximal partners of the organellar N-terminal acetyltransferase NAA60: insights into Golgi structure and transmembrane protein topology7
The role of endothelial-derived factors in neural tube development: implications for organoid models7
Correction to: ‘The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence’ (2016), by Burla et al.7
Characterization of microglia behaviour in healthy and pathological conditions with image analysis tools7
Improvement of the antibody-dependent respiratory burst assay for assessing protective immune responses to malaria7
The immune deficiency and c-Jun N-terminal kinase pathways drive the functional integration of the immune and circulatory systems of mosquitoes7
IFNγ-dependent silencing of TFF1 during Helicobacter pylori infection7
Reinventing the spermatheca: unveiling a novel sperm storage organ in Epilachninae ladybirds7
Expression of concern: ‘Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p’ (2020), by Cui Z et al.7
Simple, streamlined, cost-effective cDNA synthesis method from cell cultures7
Evaluating the efficacy of protein quantification methods on membrane proteins7
Patterning principles of morphogen gradients7
The cytosolic form of dual localized BolA family protein Bol3 is important for adaptation to iron starvation in Aspergillus fumigatus7
The CoREST complex regulates multiple histone modifications temporal-specifically in clock neurons6
The fission yeast NDR kinase Orb6 and its signalling pathway MOR regulate cytoplasmic microtubule organization during the cell cycle6
A high-throughput protein tagging toolkit that retains endogenous untranslated regions for studying gene regulation in kinetoplastids6
Gut microbiota diversity affects fish behaviour and is influenced by host genetics and early rearing conditions6
POU-M2 promotes juvenile hormone biosynthesis by directly activating the transcription of juvenile hormone synthetic enzyme genes in Bombyx mori6
Mitochondrial biology and dysfunction in secondary mitochondrial disease6
Single-molecule tracking (SMT) and localization of SRF and MRTF transcription factors during neuronal stimulation and differentiation6
In vivoassessment of mechanical properties during axolotl development and regeneration using confocal Brillouin microscopy6
A novel FAM83G variant from palmoplantar keratoderma patient disrupts WNT signalling via loss of FAM83G-CK1α interaction6
The histone deacetylase inhibitor Scriptaid targets G-quadruplexes6
Structure and molecular basis of spermatid elongation in theDrosophilatestis6
Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-26
Spatial activation of ezrin by epidermal growth factor receptor and focal adhesion kinase co-ordinates epithelial cell migration6
Multi-epitope vaccine candidates based on mycobacterial membrane protein large (MmpL) proteins against Mycobacterium ulcerans6
Plasmodium berghei leucine-rich repeat protein 1 downregulates protein phosphatase 1 activity and is required for efficient oocyst development6
Unveiling the functional nature of retrogenes in dinoflagellates6
The human HELQ helicase and XRN2 exoribonuclease cooperate in R-loop resolution6
Haploidy-linked cell proliferation defects limit larval growth in zebrafish6
Regional random mutagenesis driven by multiple sgRNAs and diverse on-target genome editing events to identify functionally important elements in non-coding regions6
Gene duplication is the primary driver of intraspecific genomic divergence in coral algal symbionts6
Microsporidian parasite impairs colony fitness in bumblebees6
Genome organization and evolution of a eukaryotic nicotinate co-inducible pathway6
PK1 from Drosophila obscurin is an inactive pseudokinase with scaffolding properties6
Sperm-borne mRNAs: potential roles in zygote genome activation and epigenetic inheritance6
Evolutionary mode for the functional preservation of fast-evolving Drosophila telomere capping proteins6
Mechanisms driving spatial distribution of residents in colony biofilms: an interdisciplinary perspective6
Unravelling the mystery of female meiotic drive: where we are6
Pattern recognition in living cells through the lens of machine learning6
The nature of ‘jaws’: a new predatory representative of Provora and the ultrastructure of nibbling protists6
Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons6
High-resolution analysis of individual Drosophila melanogaster larvae uncovers individual variability in locomotion and its neurogenetic modulation6
MYC regulates metabolism through vesicular transfer of glycolytic kinases5
Ultrastructure expansion microscopy in Trypanosoma brucei5
tRNA copy number and codon usage in the sea cucumber genome provide insights into adaptive translation for saponin biosynthesis5
Live-cell microscopy or fluorescence anisotropy with budded baculoviruses—which way to go with measuring ligand binding to M 4 muscarinic receptors?5
Controlling the topology of mammalian mitochondrial DNA5
Bacterial division ring stabilizing ZapA versus destabilizing SlmA modulate FtsZ switching between biomolecular condensates and polymers5
Live imaging YAP signalling in mouse embryo development5
Mutant SPART causes defects in mitochondrial protein import and bioenergetics reversed by Coenzyme Q5
Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation5
The information overload, immunology and their relationship to world health5
Ovothiol ensures the correct developmental programme of the sea urchin Paracentrotus lividus embryo5
Cell wall deficiency as an escape mechanism from phage infection5
Correction to ‘Global pleiotropic effects in adaptively evolved Escherichia coli lacking CRP reveal molecular mechanisms that define the growth physiology’5
Retraction: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui et al.5
From intestine to beyond: Salmonella entry factors display distinct transcription pattern upon infection in murine models5
Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes5
ELMOD3-Rab1A-Flotillin2 cascade regulates lumen formation via vesicle trafficking inCionanotochord5
Primary cilia and lipid raft dynamics5
ATP-dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming5
AMPK phosphorylates NAMPT to regulate NAD + homeostasis under ionizing radiation5
Cell cycle visualization tools to study cardiomyocyte proliferation in real-time5
The cuticular wax composition and crystal coverage of leaves and petals differ in a consistent manner between plant species5
NFIL3 contributes to cytotoxic T lymphocyte-mediated killing5
Cell autonomous and non-autonomous consequences of deviations in translation machinery on organism growth and the connecting signalling pathways5
Molecular and morphological approach to study the innexin gap junctions in Rhynchosciara americana5
Greatwall-Endos-PP2A/B55 Twins network regulates translation and stability of maternal transcripts in the Drosophila oocyte-to-embryo 5
Restricting a single amino acid cross-protects Drosophila melanogaster from nicotine poisoning through mTORC1 and GCN2 signalling5
Recent advances in understanding of enterobacterial common antigen synthesis and regulation5
Skewed distribution of spines is independent of presynaptic transmitter release and synaptic plasticity, and emerges early during adult neurogenesis4
Opium alkaloids, biosynthesis, pharmacology and association with cancer occurrence4
Metabolic control of epigenetic rearrangements in B cell pathophysiology4
Expansion microscopy facilitates quantitative super-resolution studies of cytoskeletal structures in kinetoplastid parasites4
Head transcriptome profiling of glossiphoniid leech ( Helobdella austinensis ) reveals clues about proboscis development4
Krüppel-homologue 1regulates the development ofTuta absolutaand its cascade regulation pattern in the juvenile hormone signalling pathway4
Single amino acid substitutions in hydrophobic cores at a head-coiled coil junction region of cohesin facilitate its release of DNA during anaphase4
Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature4
Kinetoplastid kinetochore proteins KKT14–KKT15 are divergent Bub1/BubR1–Bub3 proteins4
Correction to: ‘The functional diversity of the POUV-class proteins across vertebrates’ (2022) by Bakhmet and Tomilin4
HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta4
Identification of PP2A-B55 targets uncovers regulation of emerin during nuclear envelope reassembly inDrosophila4
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