Fluids and Barriers of the Cns

Papers
(The median citation count of Fluids and Barriers of the Cns is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
A scoping review of the discrepancies in the measurement of cerebral blood flow in idiopathic intracranial hypertension: oligemia, euvolemia or hyperemia?173
CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension121
A novel method of fabricating dynamic, heterogenous benchtop lateral and third ventricle phantoms from MRI of hydrocephalus patients: a verification and validation study101
Modeling neurovascular dysfunction in Alzheimer’s disease using an isogenic brain-chip model85
The hypervirulent Group B Streptococcus HvgA adhesin promotes central nervous system invasion through transcellular crossing of the choroid plexus76
miRNA-ome plasma analysis unveils changes in blood–brain barrier integrity associated with acute liver failure in rats71
The effects of dose, valency, and affinity on TfR-mediated brain delivery in vivo66
Bridging the blood-brain barrier: strategies to improve delivery of biologics to tumors in the brain64
Bridging regional neurovascular unit heterogeneity and cognitive function: a review62
Distribution of transgene in the rodent choroid plexus after intracerebroventricular injection of adeno-associated virus58
Ex vivo nanoscale abluminal mapping of putative cargo receptors at the blood-brain barrier of expanded brain capillaries56
Translational biomarkers of hypoxic brain injury uncovered in CSF secreting human choroid plexus organoids55
Effect of intracerebral infusion rate on optic nerve tissue pressure and diurnal intracranial pressure in rats49
Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study47
Age, dose, and binding to TfR on blood cells influence brain delivery of a TfR-transported antibody46
White matter lesions associated with the reemergence of grasp reflexes in patients with idiopathic normal pressure hydrocephalus46
Natural killer cells and regulatory T cells in aneurysmal subarachnoid hemorrhage in peripheral blood and cerebrospinal fluid - a pilot study45
The proteome of the blood–brain barrier in rat and mouse: highly specific identification of proteins on the luminal surface of brain microvessels by in vivo glycocapture45
Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage42
A human pluripotent stem cell-derived in vitro model of the blood–brain barrier in cerebral malaria41
Oxidative stress alters mitochondrial homeostasis in isolated brain capillaries40
Estimates of the permeability of extra-cellular pathways through the astrocyte endfoot sheath39
CSF Aquaporin-4 levels in controls and in idiopathic normal pressure hydrocephalus before and after shunt surgery38
High affinity of β-amyloid proteins to cerebral capillaries: implications in chronic lead exposure-induced neurotoxicity in rats38
Bi-component modeling of cerebrospinal fluid outflow using Time-SLIP MRI37
BOLD-CSF dynamics assessed using real-time phase contrast CSF flow interleaved with cortical BOLD MRI36
Exploring and translating novel approaches targeting the choroid plexus for the treatment of hydrocephalus: a literature review36
Commentary on “Structural characterization of SLYM – a 4th meningeal membrane”35
Evaluation of CSF albumin quotient in neuronal surface antibody-associated autoimmune encephalitis34
Early-onset ventriculomegaly and neuroimmune alterations in Hoatz-deficient mice34
Impact of age on the cerebrospinal fluid spaces: high-convexity and medial subarachnoid spaces decrease with age34
Concentration gradients of monoamines, their precursors and metabolites in serial lumbar cerebrospinal fluid of neurologically healthy patients determined with a novel LC–MS/MS technique33
Endothelial cells temporally orchestrate lymphocyte dynamics and functional outcomes after ischemic stroke33
Rh-relaxin-2 attenuates oxidative stress and neuronal apoptosis via ERK-nNOS-NO pathway after germinal matrix hemorrhage in rats32
Comparative analysis of hippocampal extracellular space uncovers widely altered peptidome upon epileptic seizure in urethane-anaesthetized rats32
Neutrophil extracellular traps aggravate blood-brain barrier disruption via ZBP1/FSP1-mediated ferroptosis after traumatic brain injury31
Ependymal cilia decline and AQP4 upregulation in young adult rats with syringomyelia31
Convergent blood–brain barrier breakdown in schizophrenia and autism spectrum disorders: a systematic review of preclinical animal models31
Isolation method of brain microvessels from small frozen human brain tissue for blood-brain barrier protein expression analysis30
Ischemic stroke: molecular mechanisms of blood-brain barrier dysfunction and opportunities for drug development29
A budget for brain metabolic water production by glucose catabolism during rest, rises in activity and sleep29
Evidence for reduced choroid plexus volume in the aged brain29
Choroid plexus modulates subventricular zone adult neurogenesis and olfaction through secretion of small extracellular vesicles28
C1-inhibitor to prevent intracerebral hemorrhage-related secondary brain injury28
Recapitulation of physiologic and pathophysiologic pulsatile CSF flow in purpose-built high-throughput hydrocephalus bioreactors27
Post-hemorrhagic hydrocephalus of prematurity is associated with disruption of tight junctions and increased macrophage activity in the choroid plexus27
Active CNS delivery of oxycodone in healthy and endotoxemic pigs27
Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome26
Longitudinal metabolomic profiling of biogenic amines in plasma and CSF, and their correlation, reveals sex-specific and age changes in TgF344 Alzheimer’s disease transgenic and wildtype rats26
Occludin: a gatekeeper of brain Infection by HIV-126
The relationship between CSF/serum immunoglobulin and albumin ratio across laboratories: a retrospective, multi-center study26
MicroRNA210 regulated brain pericyte dysfunction exacerbates hypoxic-ischemic brain injury in neonatal mice26
Morphological and mitochondrial changes in murine choroid plexus epithelial cells during healthy aging26
Choroid plexus enlargement in amyotrophic lateral sclerosis patients and its correlation with clinical disability and blood-CSF barrier permeability26
Evaluation of shunt valve flow dynamics in series26
Modulation of striatal glutamatergic, dopaminergic and cholinergic neurotransmission pathways concomitant with motor disturbance in rats with kaolin-induced hydrocephalus25
VIEshunt: towards a ventricular intelligent and electromechanical shunt for hydrocephalus therapy25
Relaxation-exchange magnetic resonance imaging (REXI): a non-invasive imaging method for evaluating trans-barrier water exchange in the choroid plexus24
Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production24
Nanoscopic analysis of tight junction organization in in vitro blood-brain barrier models24
Circadian timing of the dystrophin associated complex across the brain and body23
Building the blood-brain barrier: a scalable self-assembling 3D model of the brain microvasculature under unidirectional flow22
ATP-binding cassette transporter inhibitor potency and substrate drug affinity are critical determinants of successful drug delivery enhancement to the brain22
Circadian misalignment potentiates blood-brain barrier disruption and mitochondria dysregulation in Zika virus infection22
Translational applicability of human blood-brain barrier spheroid models for the development of brain-penetrant therapeutic antibodies22
Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"22
Characterization of blood-brain barrier L-arginine uptake using in situ brain perfusions in a female mouse model22
The new insight into the inflammatory response following focused ultrasound-mediated blood–brain barrier disruption22
Intracranial pressure following surgery of an unruptured intracranial aneurysm—a model for normal intracranial pressure in humans22
The choroid plexus and its role in the pathogenesis of neurological infections22
Transmantle pressure under the influence of free breathing: non-invasive quantification of the aqueduct pressure gradient in healthy adults22
Novel localization of folate transport systems in the murine central nervous system21
The impact of chronic and acute sleep deprivation on key Alzheimer’s disease biomarkers: a systematic review and meta-analysis21
Plasma and cerebrospinal fluid concentrations of neurofilament light protein correlate in patients with idiopathic normal pressure hydrocephalus21
Enhanced in vivo blood brain barrier transcytosis of macromolecular cargo using an engineered pH-sensitive mouse transferrin receptor binding nanobody20
Blue light exposure collapses the inner blood-retinal barrier by accelerating endothelial CLDN5 degradation through the disturbance of GNAZ and the activation of ADAM1720
Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus20
Nuclear receptor ligand screening in an iPSC-derived in vitro blood–brain barrier model identifies new contributors to leptin transport20
Relevance of choroid plexus volumes in multiple sclerosis20
Hydraulic resistance of three-dimensional pial perivascular spaces in the brain19
Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line19
Modulation of cerebrospinal fluid secretion facilitated by serotonergic and noradrenergic receptors in the rat choroid plexus19
Navigating the blood–brain barrier to blood–brain tumor barrier transition: microvascular P-glycoprotein and CD146 potentially contribute to glioma grading19
Hippocampal vascularization pattern and cerebral blood flow cooperatively modulate hippocampal tolerable amount of Aβ deposition in the occurrence of MCI18
Cerebrovascular claudin-5 isoform expression correlates with worsened stroke outcomes following thromboembolic stroke18
Acute amyloid-β exposure disrupts insulin signaling in hCMEC/D3 blood–brain barrier endothelial cells18
Transport pathways across the blood-brain barrier for waste clearance and drug delivery18
The effect of shunt surgery on corticospinal excitability in idiopathic normal pressure hydrocephalus: a transcranial magnetic stimulation study18
A retrospective longitudinal analysis of risk factors, treatment outcomes and imaging parameters of ventricular collapse in idiopathic intracranial hypertension18
Perivascular spaces balance vascular dimensions without impairing brain clearance mechanisms18
Glucocorticoids modify intracranial pressure in freely moving rats18
Estimation of human brain fluid clearance using intrathecal imaging contrast agents18
Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer´s disease and type two diabetes18
Endothelial and mural laminin-α5 contributes to neurovascular integrity maintenance17
Eppur si muove: the dynamic brain pericyte17
Research priorities for improving cognitive and neuropsychological outcomes in hydrocephalus17
Evaluating the additive properties of differential pressure valves in a novel benchtop shunt model17
Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells17
Application of a new MDCKII-MDR1 cell model to measure the extent of drug distribution in vitro at equilibrium for prediction of in vivo unbound brain-to-plasma drug distribution17
In vivo brain delivery of BBB-enabled iduronate 2-sulfatase in rats17
Data-independent acquisition proteomic analysis of the brain microvasculature in Alzheimer’s disease identifies major pathways of dysfunction and upregulation of cytoprotective responses16
Estimation of metabolic water production in human and rat brain and spinal cord16
Functions of the basal lamina and ApoE in cerebral amyloid angiopathy16
Brain ventricle morphology markers in predicting shunt surgery outcome in idiopathic normal-pressure hydrocephalus16
Role of cerebroventricular size and surgical placement in modulating catheter flow distribution16
Disentangling the impact of cerebrospinal fluid formation and neuronal activity on solute clearance from the brain16
Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson’s disease-like neurodegeneration16
Identifying molecular tags selectively retained on the surface of brain endothelial cells to generate artificial targets for therapy delivery16
[11C]Metoclopramide PET can detect a seizure-induced up-regulation of cerebral P-glycoprotein in epilepsy patients15
Blood pressure lowering enhances cerebrospinal fluid efflux to the systemic circulation primarily via the lymphatic vasculature15
Brain fluid physiology in ischaemic stroke; more than just oedema15
Research priorities for non-invasive therapies to improve hydrocephalus outcomes15
Measuring CSF net velocity in the human subarachnoid space with 7T MRI: testing the classical view of CSF absorption15
Gut microbiota modulates CNS barrier function in murine model for multiple sclerosis15
Analysis of the contributing role of drug transport across biological barriers in the development and treatment of chemotherapy-induced peripheral neuropathy15
Is the ischemia found in normal pressure hydrocephalus secondary to venous compression or arterial constriction? A comment on Ohmura et al15
Blinded gait assessment in idiopathic normal pressure hydrocephalus: reliability and correlation with clinical and patient-reported outcomes15
Consequences of irradiation on blood-brain tumor barrier model of Diffuse Midline Glioma: characterization of physical and metabolic properties15
Correction: impact of sex differences on thrombin‑induced hydrocephalus and white matter injury: the role of neutrophils15
Mucopolysaccharidoses and the blood–brain barrier15
VHHs as tools for therapeutic protein delivery to the central nervous system15
Effects of bacterial and viral pathogen-associated molecular patterns (PAMPs) on multidrug resistance (MDR) transporters in brain endothelial cells of the developing human blood–brain barrier15
Imaging the distribution and drainage of fluid in the human olfactory regions using intravenous Gadolinium-based contrast agents (GBCA) enhanced MRI15
Abstracts from Hydrocephalus World Congress 202514
Evaluation of diurnal and postural intracranial pressure employing telemetric monitoring in idiopathic intracranial hypertension14
Breakthroughs in choroid plexus and CSF biology from the first European Choroid plexus Scientific Forum (ECSF)14
Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increases both crossing and protective effects on a blood–brain barrier model14
Cognitive decline, Aβ pathology, and blood–brain barrier function in aged 5xFAD mice14
Induction of subtle blood-brain barrier dysfunction using preclinical diagnostic ultrasound combined with microbubbles14
Cognitive assessment methods and outcomes following shunt surgery in idiopathic normal pressure hydrocephalus (iNPH): a systematic review and meta-analysis14
Large-scale in-silico analysis of CSF dynamics within the subarachnoid space of the optic nerve14
Correction: Theoretical analysis of wake/sleep changes in brain solute transport suggests a flow of interstitial fluid14
Mouse embryonic stem cell-derived blood–brain barrier model: applicability to studying antibody triggered receptor mediated transcytosis14
Significant individual variation in cardiac-cycle-linked cerebrospinal fluid production following subarachnoid hemorrhage13
Cerebrospinal fluid shunt surgery reduces the risk of developing dementia and Alzheimer’s disease in patients with idiopathic normal pressure hydrocephalus: a nationwide population-based propensity-we13
Relationship between brain iron dynamics and blood-brain barrier function during childhood: a quantitative magnetic resonance imaging study13
Immunohistochemical visualization of lymphatic vessels in human dura mater: methodological perspectives13
Venous compression causes chronic cerebral ischaemia in normal pressure hydrocephalus patients13
Human intracranial pulsatility during the cardiac cycle: a computational modelling framework13
Choroid plexus immune cell response in murine hydrocephalus induced by intraventricular hemorrhage13
Transient intracranial pressure elevations (B waves) are associated with sleep apnea12
Novel paracellular marker based on ᴅ-dipeptide structure for highly sensitive quantification with UPLC-MS/MS for in vitro and in vivo blood-brain barrier permeability analysis12
The circadian clock in the choroid plexus drives rhythms in multiple cellular processes under the control of the suprachiasmatic nucleus12
Cerebrospinal fluid dynamics and subarachnoid space occlusion following traumatic spinal cord injury in the pig: an investigation using magnetic resonance imaging12
Correction: Effects of aging on hydrocephalus after intraventricular hemorrhage11
The choroid plexus: a door between the blood and the brain for tissue-type plasminogen activator11
Microfluidic models of the neurovascular unit: a translational view11
NX210c drug candidate peptide strengthens mouse and human blood-brain barriers11
Brain endothelial permeability, transport, and flow assessed over 10 orders of magnitude using the in situ brain perfusion technique11
Commentary on “Transient intracranial pressure elevations (B waves) associated with sleep apnea”: the neglected role of cyclic alternating pattern11
Mechanistic multiphysics modeling reveals how blood pulsation drives CSF flow, pressure, and brain deformation under physiological and injection conditions11
Local perfusion of capillaries reveals disrupted beta-amyloid homeostasis at the blood-brain barrier in Tg2576 murine Alzheimer’s model11
Focused ultrasound-mediated temozolomide delivery into intact blood–brain barrier tissue improves survival in patient-derived xenograft model of glioblastoma11
Inhibition of lysophosphatidic acid receptor 1 relieves PMN recruitment in CNS via LPA1/TSP1/CXCR2 pathway and alleviates disruption on blood-brain barrier following intracerebral haemorrhage in mice11
Idiopathic normal pressure hydrocephalus: associations between CSF biomarkers, clinical symptoms, and outcome after shunt surgery11
[1-11C]-Butanol Positron Emission Tomography reveals an impaired brain to nasal turbinates pathway in aging amyloid positive subjects11
Formation of metabolic water by aerobic glucose oxidation11
Exogenous laminin exhibits a unique vascular pattern in the brain via binding to dystroglycan and integrins11
Endothelial tPA-dependent recruitment of microglia to vessels protects the blood-brain barrier after stroke11
Fasting upregulates the monocarboxylate transporter MCT1 at the rat blood-brain barrier through PPAR δ activation11
Breaking boundaries: role of the brain barriers in metastatic process11
Kidins220-deficient hydrocephalus mice exhibit altered glial phenotypes and AQP4 differential regulation in the retina and optic nerve, with preserved retinal ganglion cell survival11
C9ORF72 patient-derived endothelial cells drive blood-brain barrier disruption and contribute to neurotoxicity11
Truncated mini LRP1 transports cargo from luminal to basolateral side across the blood brain barrier11
Circulating sphingosine-1-phosphate depletion is associated with endothelial activation and altered brain-endothelial S1P pathway expression in ischemic stroke10
Nocturnal increase in cerebrospinal fluid secretion as a circadian regulator of intracranial pressure10
Imaging the neurovascular unit in health and neurodegeneration: a scoping review of interdependencies between MRI measures10
Correction to: Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells10
Single-cell analysis of mesenchymal cells in permeable neural vasculature reveals novel diverse subpopulations of fibroblasts10
Deep learning segmentation of the choroid plexus from structural magnetic resonance imaging (MRI): validation and normative ranges across the adult lifespan10
Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure10
Abstracts from Hydrocephalus 2024: The 16th Meeting of the Hydrocephalus Society10
Lumped parameter simulations of cervical lymphatic vessels: dynamics of murine cerebrospinal fluid efflux from the skull10
Targeting NLRP3 signaling with a novel sulfonylurea compound for the treatment of vascular cognitive impairment and dementia10
CSF outflow from the human spinal canal: preliminary results from an anatomical specimen-based model10
Synchronous quantification of arterial, venous, and cerebrospinal fluid flow dynamics using real-time phase-contrast MRI10
Movement of cerebrospinal fluid tracer into brain parenchyma and outflow to nasal mucosa is reduced at 24 h but not 2 weeks post-stroke in mice10
Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells10
Patient-specific CFD modeling of CSF flow in Chiari I malformation: denticulate-ligament-induced compartmentalization explains flow patterns10
BBB proteomic analysis reveals that complex febrile seizures in infancy enhance susceptibility to epilepsy in adulthood through dysregulation of ECM-receptor interaction signaling pathway9
Reducing assessment timing in Tap-Test-positive patients with iNPH: a 24-hour strategy and the exploratory role of the Symbol-Digit Modalities Test in surgical triage9
A tissue-engineered model of the blood-tumor barrier during metastatic breast cancer9
A patient-derived amyotrophic lateral sclerosis blood-brain barrier model for focused ultrasound-mediated anti-TDP-43 antibody delivery9
Exploring the ability of plasma pTau217, pTau181 and beta-amyloid in mirroring cerebrospinal fluid biomarker profile of Mild Cognitive Impairment by the fully automated Lumipulse® platform9
Choroid plexus volume in brain disorders: a systematic review9
IIIG9 and PP1α form a protein complex in the adherens junctions of polarized ependymal and MDCK cells9
Slow unsteady gait in a population-based cohort: links to ventriculomegaly and INPH-related imaging markers9
Compartmentalized VEGF receptor expression in hypothalamic tanycytes reveals a novel non-endothelial axis of VEGF signaling9
Blood-brain barrier disruption: a culprit of cognitive decline?9
Low interstitial fluid in patients with spontaneous intracranial hypotension9
Blood-brain barrier water permeability is elevated in type 2 diabetes and obesity: associations with cognitive function and metabolic markers9
Review of the lumbar infusion test use in pediatric populations: state-of-the-art and future perspectives9
Characterization of passive permeability after low intensity focused ultrasound mediated blood–brain barrier disruption in a preclinical model9
The effect of A1 and A2 reactive astrocyte expression on hydrocephalus shunt failure9
Pulsatile cerebral paraarterial flow by peristalsis, pressure and directional resistance9
Uric acid and ammonia play synergistic roles in the loss of blood-brain barrier integrity in the context of hepatic encephalopathy9
Role of transforming growth factorβ in neurovascular unit during cerebral small vessel disease9
Spatiotemporal arising of molecular and functional blood-brain barrier properties in the developing Gallus gallus optic tectum9
Blood-brain barrier permeability increases with the differentiation of glioblastoma cells in vitro8
Characteristics of patients with idiopathic normal pressure hydrocephalus for whom neurosurgeons hesitate to perform shunt surgery: a nationwide hospital-based survey in Japan8
In response to Mutti et al. 2024 commentary on “Transient intracranial pressure elevations (B waves) associated with sleep apnea: the neglected role of cyclic alternating pattern”8
Targeting CD4⁺ T cell infiltration: mechanisms and therapeutic insights into CD4⁺ T cell transmigration across the blood–brain barrier in acute ischemic stroke8
Imaging blood to periarterial CSF flow coupling using 4D flow MRI and an ultra-high-performance head-only gradient system8
Cerebral arterial flow dynamics during systole and diastole phases in young and older healthy adults8
Mutated LRRK2 induces a reactive phenotype and alters migration in human iPSC-derived pericyte-like cells8
Elevated neurofilament light chain CSF/serum ratio indicates impaired CSF outflow in idiopathic intracranial hypertension8
APPswe mutation causes functional deficits in endothelial cells generated by transient ETV2 overexpression in human iPSCs8
Validating the accuracy of real-time phase-contrast MRI and quantifying the effects of free breathing on cerebrospinal fluid dynamics8
Exploring dysfunctional barrier phenotypes associated with glaucoma using a human pluripotent stem cell-based model of the neurovascular unit8
Choroid plexus organoids reveal mechanisms of Streptococcus suis translocation at the blood-cerebrospinal fluid barrier8
Role of aging in Blood–Brain Barrier dysfunction and susceptibility to SARS-CoV-2 infection: impacts on neurological symptoms of COVID-198
Cerebral blood flow, autoregulation and vascular reactivity in normal pressure hydrocephalus: a systematic review7
Motor network neurophysiological (TMS-EEG) markers as predictors of outcomes of ventriculoperitoneal shunt sustained for over a year in normal pressure hydrocephalus7
Activation of NMDA receptors in brain endothelial cells increases transcellular permeability7
Time-of-day and age-related patterns in cerebrospinal fluid glucose and protein7
Deformation of brain in normal pressure hydrocephalus is more readily associated with slow vasomotion rather than heartbeat related pulsations of intracranial pressure7
Levels of inflammatory cytokines MCP-1, CCL4, and PD-L1 in CSF differentiate idiopathic normal pressure hydrocephalus from neurodegenerative diseases7
Reduced folate carrier 1 is present in retinal microvessels and crucial for the inner blood retinal barrier integrity7
Inhibition of histone deacetylase 6 activity mitigates neurological impairment and post-hemorrhagic hydrocephalus after intraventricular hemorrhage by modulating pyroptosis and autophagy pathways7
Unique features of the arterial blood–brain barrier7
Cerebral venous outflow disturbance exacerbates ischemic stroke via an endothelium-initiated inflammatory cascade: an integrated single-cell transcriptomic analysis7
Ventriculosagittal sinus shunt for treating hydrocephalus with elevated cerebrospinal fluid protein7
iPSC-derived blood-brain barrier modeling reveals APOE isoform-dependent interactions with amyloid beta7
A transcriptomic analysis of cerebral microvessels reveals the involvement of Notch1 signaling in endothelial mitochondrial-dysfunction-dependent BBB disruption7
Clinical characteristics and outcomes after shunt surgery in idiopathic normal pressure hydrocephalus with or without prior cerebrospinal fluid tap testing: a single-center follow-up study of 481 pati6
Involvement of the choroid plexus in Alzheimer’s disease pathophysiology: findings from mouse and human proteomic studies6
Intraventricular iron causes severe hydrocephalus – a model of severe neonatal hydrocephalus6
In vitro investigation of the effect of proinflammatory cytokines on mouse choroid plexus membrane transporters Ncbe and NKCC16
Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes6
CSF dynamics throughout the ventricular system using 4D flow MRI: associations to arterial pulsatility, ventricular volumes, and age6
Hyphal penetration is the major pathway of translocation of Candida albicans across the blood-cerebrospinal fluid barrier6
Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries6
Mass spectrometry-based proteomics of cerebrospinal fluid in pediatric central nervous system malignancies: a systematic review with meta-analysis of individual patient data6
The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis6
Sizes and shapes of perivascular spaces surrounding murine pial arteries6
Sleep reduces CSF concentrations of beta-amyloid and tau: a randomized crossover study in healthy adults6
Hemodynamic and morphologic adaptations of the dural venous sinus to 7-day −6° head-down tilt and recovery: an eight-timepoint 4D flow MRI longitudinal study6
Pumilio-1 mediated translational control of claudin-5 at the blood-brain barrier6
Distinct volumetric features of cerebrospinal fluid distribution in idiopathic normal-pressure hydrocephalus and Alzheimer’s disease6
Single-cell RNA sequencing reveals disease associated changes in brain endothelial cells in the 5XFAD mouse6
Quantitative evaluation of low-frequency oscillations using real-time phase-contrast MRI during drowsiness6
Rutin ameliorates stress–induced blood‒brain barrier dysfunction and cognitive decline via the endothelial HDAC1‒Claudin–5 axis6
Postnatal meningeal CSF transport is primarily mediated by the arachnoid and pia maters and is not altered after intraventricular hemorrhage-posthemorrhagic hydrocephalus6
Transient but not chronic hyperglycemia accelerates ocular glymphatic transport6
Correction: Role of cerebroventricular size and surgical placement in modulating catheter flow distribution5
Neurogenesis and glial impairments in congenital hydrocephalus: insights from a BioGlue-induced fetal lamb model5
Are standing osmotic gradients the main driver of cerebrospinal fluid production? A computational analysis5
A year in review: brain barriers and brain fluids research in 20225
Plasma biomarkers of Alzheimer’s disease and their association with disproportionately enlarged subarachnoid space hydrocephalus5
Response to Commentary on “Structural characterization of SLYM – a 4th meningeal membrane” by Julie Siegenthaler and Christer Betsholtz5
0.08095908164978