OOIR: Observatory of International Research

Papers

(The H4-Index of Fluids and Barriers of the Cns is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Advances in brain barriers and brain fluids research in 2021: great progress in a time of adversity	149
Investigating post-traumatic syringomyelia and local fluid osmoregulation via a rat model	132
Hippocampal vascularization pattern and cerebral blood flow cooperatively modulate hippocampal tolerable amount of Aβ deposition in the occurrence of MCI	78
The impact of chronic mild hypoxia on cerebrovascular remodelling; uncoupling of angiogenesis and vascular breakdown	74
Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1	70
Retirement of Dr. Hazel Jones as Co-Editor-in-Chief of Fluids and Barriers of the CNS. Dr. Mark Hamilton becomes Co-Editor-in-Chief	60
Abstracts from Hydrocephalus 2021: The Thirteenth Meeting of the International Society for Hydrocephalus and Cerebrospinal Fluid Disorders	59
Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies	57
Brain pharmacokinetics of mono- and bispecific amyloid-β antibodies in wild-type and Alzheimer’s disease mice measured by high cut-off microdialysis	56
Blood-spinal cord barrier disruption in degenerative cervical myelopathy	53
CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension	50
Exploring ITM2A as a new potential target for brain delivery	49
Expression and functions of adenylyl cyclases in the CNS	48
Long-term administration of CU06-1004 ameliorates cerebrovascular aging and BBB injury in aging mouse model	47
The influence of upright posture on craniospinal, arteriovenous, and abdominal pressures in a chronic ovine in-vivo trial	44
The effect of A1 and A2 reactive astrocyte expression on hydrocephalus shunt failure	44
Numerical study of the effects of minor structures and mean velocity fields in the cerebrospinal fluid flow	40
A metabolomics study in aqueous humor discloses altered arginine metabolism in Parkinson’s disease	39
Physical exercise and goal attainment after shunt surgery in idiopathic normal pressure hydrocephalus: a randomised clinical trial	37
Diagnostic biomarker kinetics: how brain-derived biomarkers distribute through the human body, and how this affects their diagnostic significance: the case of S100B	37
Lumped parameter simulations of cervical lymphatic vessels: dynamics of murine cerebrospinal fluid efflux from the skull	35
Research priorities for improving cognitive and neuropsychological outcomes in hydrocephalus	33
Modeling cerebrospinal fluid dynamics across the entire intracranial space through integration of four-dimensional flow and intravoxel incoherent motion magnetic resonance imaging	33
White matter changes should not exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery	31
Characterization of passive permeability after low intensity focused ultrasound mediated blood–brain barrier disruption in a preclinical model	30

A tissue-engineered model of the blood-tumor barrier during metastatic breast cancer	30
Endothelial and mural laminin-α5 contributes to neurovascular integrity maintenance	30
Choroid plexus aging: structural and vascular insights from the HCP-aging dataset	29
Application of a new MDCKII-MDR1 cell model to measure the extent of drug distribution in vitro at equilibrium for prediction of in vivo unbound brain-to-plasma drug distribution	29
Brain barriers virtual: an interim solution or future opportunity?	29