OOIR: Observatory of International Research

Papers

(The H4-Index of Fluids and Barriers of the Cns is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity	797
The glymphatic hypothesis: the theory and the evidence	119
Extracellular vesicles through the blood–brain barrier: a review	89
Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited	63
The regulatory roles of motile cilia in CSF circulation and hydrocephalus	58
Reduction in pericyte coverage leads to blood–brain barrier dysfunction via endothelial transcytosis following chronic cerebral hypoperfusion	56
SARS-CoV-2: is there neuroinvasion?	49
The blood–brain barrier and the neurovascular unit in subarachnoid hemorrhage: molecular events and potential treatments	47
Decreased CSF clearance and increased brain amyloid in Alzheimer’s disease	46
Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size	38
Modeling ischemic stroke in a triculture neurovascular unit on-a-chip	38
Mechanisms of neuroinflammation in hydrocephalus after intraventricular hemorrhage: a review	37
Direction and magnitude of cerebrospinal fluid flow vary substantially across central nervous system diseases	37
Cerebrospinal fluid drainage kinetics across the cribriform plate are reduced with aging	37
Reference values for intracranial pressure and lumbar cerebrospinal fluid pressure: a systematic review	36
The choroid plexus and its role in the pathogenesis of neurological infections	36
The CLDN5 gene at the blood-brain barrier in health and disease	32
Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1	31
Investigating receptor-mediated antibody transcytosis using blood–brain barrier organoid arrays	31
Non-coding RNAs in the regulation of blood–brain barrier functions in central nervous system disorders	30
Exploring mechanisms of ventricular enlargement in idiopathic normal pressure hydrocephalus: a role of cerebrospinal fluid dynamics and motile cilia	30
Expression and functions of adenylyl cyclases in the CNS	29
Neural crest cell-derived pericytes act as pro-angiogenic cells in human neocortex development and gliomas	28
Presence of a mutation in PSEN1 or PSEN2 gene is associated with an impaired brain endothelial cell phenotype in vitro	27
The relationship between cerebral blood flow and venous sinus pressure: can hyperemia induce idiopathic intracranial hypertension?	26

Epigenetics in blood–brain barrier disruption	26
Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model	26