OOIR: Observatory of International Research

Papers

(The H4-Index of Fluids and Barriers of the Cns is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Bridging regional neurovascular unit heterogeneity and cognitive function: a review	245
Modeling neurovascular dysfunction in Alzheimer’s disease using an isogenic brain-chip model	141
The effects of dose, valency, and affinity on TfR-mediated brain delivery in vivo	111
CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension	93
Bridging the blood-brain barrier: strategies to improve delivery of biologics to tumors in the brain	73
A scoping review of the discrepancies in the measurement of cerebral blood flow in idiopathic intracranial hypertension: oligemia, euvolemia or hyperemia?	65
A novel method of fabricating dynamic, heterogenous benchtop lateral and third ventricle phantoms from MRI of hydrocephalus patients: a verification and validation study	65
The hypervirulent Group B Streptococcus HvgA adhesin promotes central nervous system invasion through transcellular crossing of the choroid plexus	62
miRNA-ome plasma analysis unveils changes in blood–brain barrier integrity associated with acute liver failure in rats	62
Age, dose, and binding to TfR on blood cells influence brain delivery of a TfR-transported antibody	59
White matter lesions associated with the reemergence of grasp reflexes in patients with idiopathic normal pressure hydrocephalus	57
Effect of intracerebral infusion rate on optic nerve tissue pressure and diurnal intracranial pressure in rats	54
Ex vivo nanoscale abluminal mapping of putative cargo receptors at the blood-brain barrier of expanded brain capillaries	53
BOLD-CSF dynamics assessed using real-time phase contrast CSF flow interleaved with cortical BOLD MRI	49
CSF Aquaporin-4 levels in controls and in idiopathic normal pressure hydrocephalus before and after shunt surgery	45
Bi-component modeling of cerebrospinal fluid outflow using Time-SLIP MRI	44
Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage	44
Oxidative stress alters mitochondrial homeostasis in isolated brain capillaries	44
Claudin-5a is essential for the functional formation of both zebrafish blood-brain barrier and blood-cerebrospinal fluid barrier	43
The proteome of the blood–brain barrier in rat and mouse: highly specific identification of proteins on the luminal surface of brain microvessels by in vivo glycocapture	43
Translational biomarkers of hypoxic brain injury uncovered in CSF secreting human choroid plexus organoids	40
Estimates of the permeability of extra-cellular pathways through the astrocyte endfoot sheath	39
High affinity of β-amyloid proteins to cerebral capillaries: implications in chronic lead exposure-induced neurotoxicity in rats	38
A human pluripotent stem cell-derived in vitro model of the blood–brain barrier in cerebral malaria	37
Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study	37

Commentary on “Structural characterization of SLYM – a 4th meningeal membrane”	37
Comparative analysis of hippocampal extracellular space uncovers widely altered peptidome upon epileptic seizure in urethane-anaesthetized rats	36
Evaluation of CSF albumin quotient in neuronal surface antibody-associated autoimmune encephalitis	35
Evidence for reduced choroid plexus volume in the aged brain	35
Early-onset ventriculomegaly and neuroimmune alterations in Hoatz-deficient mice	35
Ependymal cilia decline and AQP4 upregulation in young adult rats with syringomyelia	35
Impact of age on the cerebrospinal fluid spaces: high-convexity and medial subarachnoid spaces decrease with age	34
Isolation method of brain microvessels from small frozen human brain tissue for blood-brain barrier protein expression analysis	34
Endothelial cells temporally orchestrate lymphocyte dynamics and functional outcomes after ischemic stroke	33