Cell and Bioscience

Article	Citations
CD44 fucosylation on bone marrow-derived mesenchymal stem cells enhances homing and promotes enteric nervous system remodeling in diabetic mice	198
Autophagy-mediated degradation of NOTCH1 intracellular domain controls the epithelial to mesenchymal transition and cancer metastasis	154
Tick-borne encephalitis affects sleep–wake behavior and locomotion in infant rats	135
Modulation of foraging-like behaviors by cholesterol-FGF19 axis	124
Neurokinin-2 receptor negatively modulates substance P responses by forming complex with Neurokinin-1 receptor	115
Clinical biomarkers for Lewy body diseases	104
Retraction Note: LncRNA SNHG7 promotes pancreatic cancer proliferation through ID4 by sponging miR-342-3p	101
Slit-Robo expression in the leech nervous system: insights into eyespot evolution	85
Bromodomain proteins as potential therapeutic targets for B-cell non-Hodgkin lymphoma	84
Generation of musculoskeletal cells from human urine epithelium-derived presomitic mesoderm cells	80
Integrative analysis of bulk and single-cell RNA sequencing reveals the gene expression profile and the critical signaling pathways of type II CPAM	77
Correction: Plasma metabolomics provides new insights into the relationship between metabolites and outcomes and left ventricular remodeling of coronary artery disease	74
Multi-omics in thoracic aortic aneurysm: the complex road to the simplification	73
Sperm-borne small non-coding RNAs: potential functions and mechanisms as epigenetic carriers	69
Retraction Note: Growth inhibition and apoptosis in colorectal cancer cells induced by vitamin D-Nanoemulsion (NVD): involvement of Wnt/β-catenin and other signal transduction pathways	64
HBx promotes tumorigenicity through RRM2-mediated autophagy in hepatocellular carcinoma	60
PI3K-AKT activation resculpts integrin signaling to drive filamentous tau-induced proinflammatory astrogliosis	58
Genome-wide association study of the fatty liver index in the Taiwanese population reveals shared and population-specific genetic risk factors across ethnicities	56
Integrating spatial transcriptomics with single-cell transcriptomics reveals a spatiotemporal gene landscape of the human developing kidney	55
Multiple responses contribute to the enhanced drought tolerance of the autotetraploid Ziziphus jujuba Mill. var. spinosa	55
Brain nuclear receptors and cardiovascular function	53
Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation	53
Metabolic reprogramming in colorectal cancer: regulatory networks and therapy	51
Microvascular destabilization and intricated network of the cytokines in diabetic retinopathy: from the perspective of cellular and molecular components	45
Single-cell genomics identifies distinct B1 cell developmental pathways and reveals aging-related changes in the B-cell receptor repertoire	44

Transcriptome-scale spatial gene expression in rat arcuate nucleus during puberty	43
A new thinking: deciphering the aberrance and clinical implication of copper-death signatures in clear cell renal cell carcinoma	42
Long-term maintenance of human endometrial epithelial stem cells and their therapeutic effects on intrauterine adhesion	41
Calcineurin inhibition protects against dopamine toxicity and attenuates behavioral decline in a Parkinson’s disease model	40
Comparative proteomic profiling of plasma exosomes in lung cancer cases of liver and brain metastasis	40
Precision nephrotoxicity testing using 3D in vitro models	39
Hypofucosylation of Unc5b regulated by Fut8 enhances macrophage emigration and prevents atherosclerosis	39
DNA methyltransferase 1 knockdown reverses PTEN and VDR by mediating demethylation of promoter and protects against renal injuries in hepatitis B virus-associated glomerulonephritis	39
Neural EGFL-like 1, a craniosynostosis-related osteochondrogenic molecule, strikingly associates with neurodevelopmental pathologies	38
Single-cell analysis of mouse uterus at the invasion phase of embryo implantation	38
A patient-derived mutation of epilepsy-linked LGI1 increases seizure susceptibility through regulating Kv1.1	38
Sex-specific hypothalamic neuropathology and glucose metabolism in an amyloidosis transgenic mouse model of Alzheimer’s disease	37
Clostridium butyricum regulates intestinal barrier function via trek1 to improve behavioral abnormalities in mice with autism spectrum disorder	37
RNA sequencing profiles reveal dynamic signaling and glucose metabolic features during bone marrow mesenchymal stem cell senescence	37
New insights into the stromal interaction molecule 2 function and its impact on the immunomodulation of tumor microenvironment	37
SARS-CoV-2 variants divergently infect and damage cardiomyocytes in vitro and in vivo	34
Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells	33
SIRT6 deficiency impairs the deacetylation and ubiquitination of UHRF1 to strengthen glycolysis and lactate secretion in bladder cancer	33
Dynamic single-cell RNA-seq analysis reveals distinct tumor program associated with microenvironmental remodeling and drug sensitivity in multiple myeloma	32
The cGAS-STING pathway in cardiovascular diseases: from basic research to clinical perspectives	32
Autophagy deficiency in neurodevelopmental disorders	32
The nerve growth factor-delivered signals in prostate cancer and its associated microenvironment: when the dialogue replaces the monologue	32
The phosphorylation to acetylation/methylation cascade in transcriptional regulation: how kinases regulate transcriptional activities of DNA/histone-modifying enzymes	32
Fibroblast-to-cardiomyocyte lactate shuttle modulates hypertensive cardiac remodelling	32
PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders	32
The multifaceted therapeutic value of targeting steroid receptor coactivator-1 in tumorigenesis	31
BVES is a novel interactor of ANO5 and regulates myoblast differentiation	31
TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation	31
Current methodologies in protein ubiquitination characterization: from ubiquitinated protein to ubiquitin chain architecture	31
Modeling of the brain-lung axis using organoids in traumatic brain injury: an updated review	31
Persistent deficiency of mucosa-associated invariant T (MAIT) cells during alcohol-related liver disease	31
Regulation of telomerase towards tumor therapy	30
Insight into the mitochondrial unfolded protein response and cancer: opportunities and challenges	30
Umbelliferone and eriodictyol suppress the cellular entry of SARS-CoV-2	30
ER Ca2+ overload activates the IRE1α signaling and promotes cell survival	30
Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on β-catenin: implications for the Wnt signaling pathway in CRC models	29
Pathological alterations in the gastrointestinal tract of a porcine model of DMD	29
CXCL11 reprograms M2-biased macrophage polarization to alleviate pulmonary fibrosis in mice	29
Influence of miR-221/222 on cardiomyocyte calcium handling and function	29
Correction to: Evolutionary divergence in tail regeneration between Xenopus laevis and Xenopus tropicalis	29
NAD+ metabolism-based immunoregulation and therapeutic potential	28
DNA in extracellular vesicles: from evolution to its current application in health and disease	28
Editorial Expression of Concern: Ginkgetin aglycone ameliorates LPS-induced acute kidney injury by activating SIRT1 via inhibiting the NF-κB signaling pathway	28
CircRNA Itm2b induces oxidative stress via the interaction with Sirt1-Nox4 to aggravate sleep disturbances after traumatic brain injury	28
Hypoxia increases RCC stem cell phenotype via altering the androgen receptor (AR)-lncTCFL5-2-YBX1-SOX2 signaling axis	27
A synthetic pregnenolone analog promotes microtubule dynamics and neural development	27
Transcriptomic characterization of tissues from patients and subsequent pathway analyses reveal biological pathways that are implicated in spastic ataxia	27
Structural basis of human PRPS2 filaments	27
Discovery and mechanism studies of a novel ATG4B inhibitor Ebselen by drug repurposing and its anti-colorectal cancer effects in mice	27
ANGPTL2 binds MAG to efficiently enhance oligodendrocyte differentiation	26

Multiple functions of autophagy in vascular calcification	25
A cost-effective machine learning-based method for preeclampsia risk assessment and driver genes discovery	25
Coffee as a dietary strategy to prevent SARS-CoV-2 infection	25
Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated IFN-B response that leads to activa	25
ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1	25
Inhibition of PI3 kinase isoform p110α suppresses neuroblastoma growth and induces the reduction of Anaplastic Lymphoma Kinase	25
Nrf2 is predominantly expressed in hippocampal neurons in a rat model of temporal lobe epilepsy	25
Cutting-edge advances in modeling the blood–brain barrier and tools for its reversible permeabilization for enhanced drug delivery into the brain	25
Macrophage-derived exosomes mediate glomerular endothelial cell dysfunction in sepsis-associated acute kidney injury	25
Inhibition of sphingolipid metabolism in osteosarcoma protects against CD151-mediated tumorigenicity	25
Deletion of ER-retention motif on SARS-CoV-2 spike protein reduces cell hybrid during cell–cell fusion	24
Correction to: Aldose reductase deficiency inhibits LPS-induced M1 response in macrophages by activating autophagy	24
Astrocyte derived TSP2 contributes to synaptic alteration and visual dysfunction in retinal ischemia/reperfusion injury	24
The regulatory mechanism of neutrophil extracellular traps in cancer biological behavior	24
The RBM39 degrader indisulam inhibits acute megakaryoblastic leukemia by altering the alternative splicing of ZMYND8	24
Unraveling the serotonin saga: from discovery to weight regulation and beyond - a comprehensive scientific review	24
V1bR enhances glucose-stimulated insulin secretion by paracrine production of glucagon which activates GLP-1 receptor	24
Subcellular localization of the mouse PRAMEL1 and PRAMEX1 reveals multifaceted roles in the nucleus and cytoplasm of germ cells during spermatogenesis	24
Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells	24
The immunological mechanisms and therapeutic potential in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity	24
The eukaryotic initiation factor 5A (eIF5A1), the molecule, mechanisms and recent insights into the pathophysiological roles	24
Changes to the identity of EndoC-βH1 beta cells may be mediated by stress-induced depletion of HNRNPD	24
Advancing equity through strengthening research on health and well-being of Asian American, Native Hawaiian, and Pacific Islander	24
Integrated single-nucleus sequencing and spatial architecture analysis identified distinct injured-proximal tubular types in calculi rats	24
Therapeutic uses of oxytocin in stress-related neuropsychiatric disorders	24
Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls	24
Canonical and non-canonical functions of the non-coding RNA component (TERC) of telomerase complex	23
Damage mechanism and therapy progress of the blood-brain barrier after ischemic stroke	23
Enpp1 ameliorates MAFLD by regulating hepatocyte lipid metabolism through the AMPK/PPARα signaling pathway	23
SETD8, a frequently mutated gene in cervical cancer, enhances cisplatin sensitivity by impairing DNA repair	23
DNA methylation of ACADS promotes immunogenic cell death in hepatocellular carcinoma	22
Rapid and robust derivation of mesenchymal stem cells from human pluripotent stem cells via temporal induction of neuralized ectoderm	22
GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes	22
TAZ deficiency exacerbates psoriatic pathogenesis by increasing the histamine-releasing factor	22
Comparison of DNA targeting CRISPR editors in human cells	22
PRCC reduces the sensitivity of cancer cells to DNA damage by inhibiting JNK and ATM/ATR pathways and results in a poor prognosis in hepatocellular carcinoma	22
Importance of the origin of mesenchymal (stem) stromal cells in cancer biology: “alliance” or “war” in intercellular signals	22
Identification of Gm15441, a Txnip antisense lncRNA, as a critical regulator in liver metabolic homeostasis	22
FACI is a novel clathrin adaptor protein 2-binding protein that facilitates low-density lipoprotein endocytosis	22
A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells	21
BRD4 inhibitor GNE987 exerts anti-cancer effects by targeting super-enhancers in neuroblastoma	21
Human skin dermis-derived fibroblasts are a kind of functional mesenchymal stromal cells: judgements from surface markers, biological characteristics, to therapeutic efficacy	21
Gut microbial metabolite deoxycholic acid facilitates Th17 differentiation through modulating cholesterol biosynthesis and participates in high-fat diet-associated colonic inflammation	21
Knocking out Fkbp51 decreases CCl4-induced liver injury through enhancement of mitochondrial function and Parkin activity	21
mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A	21
Bone morphogenetic protein signaling regulation of AMPK and PI3K in lung cancer cells and C. elegans	21
Macrophages derived from pluripotent stem cells: prospective applications and research gaps	20
Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis	20
Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax	20
Neutrophil extracellular traps promote thrombogenicity in cerebral venous sinus thrombosis	20
Metabolic reprogramming and metabolic sensors in KSHV-induced cancers and KSHV infection	20
YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner	20
Klotho exerts protection in chronic kidney disease associated with regulating inflammatory response and lipid metabolism	20
CD24+LCN2+ liver progenitor cells in ductular reaction contributed to macrophage inflammatory responses in chronic liver injury	20
A translational perspective of the malignant hematopoietic proteoglycome	20
The SIRT7-mediated deacetylation of CHD1L amplifies HIF-2α-dependent signal that drives renal cell carcinoma progression and sunitinib resistance	19
Comparison of characteristics and immune responses between paired human nasal and bronchial epithelial organoids	19
SK3 in POMC neurons plays a sexually dimorphic role in energy and glucose homeostasis	19
The lncRNA MIR181A1HG in extracellular vesicles derived from highly metastatic colorectal cancer cells promotes liver metastasis by remodeling the extracellular matrix and recruiting myeloid-derived s	19
TSA-PACT: a method for tissue clearing and immunofluorescence staining on zebrafish brain with improved sensitivity, specificity and stability	19
A SNARE protective pool antagonizes APOL1 renal toxicity in Drosophila nephrocytes	18
Intranasal HD-Ad vaccine protects the upper and lower respiratory tracts of hACE2 mice against SARS-CoV-2	18
Intensity-dependent gamma electrical stimulation regulates microglial activation, reduces beta-amyloid load, and facilitates memory in a mouse model of Alzheimer’s disease	18
MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning	18
Correction: RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma	18
Epigallocatechin gallate from green tea effectively blocks infection of SARS-CoV-2 and new variants by inhibiting spike binding to ACE2 receptor	18
Unconventional protein post-translational modifications: the helmsmen in breast cancer	18
Predictive and prognostic biomarkers of bone metastasis in breast cancer: current status and future directions	18
The RNA binding protein CARHSP1 facilitates tumor growth, metastasis and immune escape by enhancing IL-17RA mRNA stabilization in prostate cancer	17
The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context	17
β-catenin mediates endodermal commitment of human ES cells via distinct transactivation functions	17
A bivalent protein targeting glycans and HR1 domain in spike protein potently inhibited infection of SARS-CoV-2 and other human coronaviruses	17
Single-cell transcriptomic analysis of normal and pathological tissues from the same patient uncovers colon cancer progression	17
Bradykinin promotes immune responses in differentiated embryonic neurospheres carrying APPswe and PS1dE9 mutations	17
Role of ammonia for brain abnormal protein glycosylation during the development of hepatitis B virus-related liver diseases	17
Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity	16
Nanotechnological engineering of extracellular vesicles for the development of actively targeted hybrid nanodevices	16
YBX1 mediates alternative splicing and maternal mRNA decay during pre-implantation development	16
Glycolysis-cholesterol metabolic axis in immuno-oncology microenvironment: emerging role in immune cells and immunosuppressive signaling	16
A novel function for α-synuclein as a regulator of NCK2 in olfactory bulb: implications for its role in olfaction	16

Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1	16
l-Arginine, as an essential amino acid, is a potential substitute for treating COPD via regulation of ROS/NLRP3/NF-κB signaling pathway	16
Multifunctional roles of γ-enolase in the central nervous system: more than a neuronal marker	16
The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo	16
Deubiquitinase USP10 promotes osteosarcoma autophagy and progression through regulating GSK3β-ULK1 axis	16
Differential impact of BRAFV600E isoforms on tumorigenesis in a zebrafish model of melanoma	16
Cardiac effects and clinical applications of MG53	16
Exosomal USP13 derived from microvascular endothelial cells regulates immune microenvironment and improves functional recovery after spinal cord injury by stabilizing IκBα	16
The versatile roles of testrapanins in cancer from intracellular signaling to cell–cell communication: cell membrane proteins without ligands	15
Targeting miR-181a/b in retinitis pigmentosa: implications for disease progression and therapy	15
Single‑cell RNA sequencing analysis of human embryos from the late Carnegie to fetal development	15
Ontogeny of RORγt+ cells in the intestine of newborns and its role in the development of experimental necrotizing enterocolitis	15
Reproductive chemical database: a curated database of chemicals that modulate protein targets regulating important reproductive biological processes	15
Dysregulated ac4C modification of mRNA in a mouse model of early-stage Alzheimer’s disease	15
Peptides targeting RAB11A–FIP2 complex inhibit HPIV3, RSV, and IAV replication as broad-spectrum antivirals	15
Development of a novel human CD147 knock-in NSG mouse model to test SARS-CoV-2 viral infection	15
Structural properties of immune complexes formed by viral antigens and specific antibodies shape the inflammatory response of macrophages	15
Revisiting potential value of antitumor drugs in the treatment of COVID-19	15
Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments	15
Intermittent hypoxia in a mouse model of apnea of prematurity leads to a retardation of cerebellar development and long-term functional deficits	15
Predictive biomarkers for the responsiveness of recurrent glioblastomas to activated killer cell immunotherapy	15
Meloxicam inhibits STING phosphorylation and alleviates intracellular DNA-mediated autoimmune responses	15
The promoting effects of activated olfactory ensheathing cells on angiogenesis after spinal cord injury through the PI3K/Akt pathway	15
A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1G93A model of ALS	15
Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathway	15
Common immunopathogenesis of central nervous system diseases: the protein-homeostasis-system hypothesis	15
Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases	15
Transcription factor E4F1 dictates spermatogonial stem cell fate decisions by regulating mitochondrial functions and cell cycle progression	15
Concurrent mapping of multiple epigenetic marks and co-occupancy using ACT2-seq	14
Timely expression of PGAM5 and its cleavage control mitochondrial homeostasis during neurite re-growth after traumatic brain injury	14
ADAMTS-1: a novel target gene of an estrogen-induced transcription factor, EGR1, critical for embryo implantation in the mouse uterus	14
Oncogenic activation revealed by FGFR2 genetic alterations in intrahepatic cholangiocarcinomas	14
Activation of Piezo1 downregulates renin in juxtaglomerular cells and contributes to blood pressure homeostasis	14
Histone deacetylase 3 facilitates TNFα-mediated NF-κB activation through suppressing CTSB induced RIP1 degradation and is required for host defense against bacterial infection	14
Astaxanthin attenuates glucose-induced liver injury in largemouth bass: role of p38MAPK and PI3K/Akt signaling pathways	14
CrebH protects against liver injury associated with colonic inflammation via modulation of exosomal miRNA	14
Human epicardial organoids from pluripotent stem cells resemble fetal stage with potential cardiomyocyte- transdifferentiation	14
Generation of mitochondria-rich kidney organoids from expandable intermediate mesoderm progenitors reprogrammed from human urine cells under defined medium	14
IFITM3 promotes malignant progression, cancer stemness and chemoresistance of gastric cancer by targeting MET/AKT/FOXO3/c-MYC axis	14
NUAK1 coordinates growth factor-dependent activation of mTORC2 and Akt signaling	14
The role of long noncoding RNAs in ocular angiogenesis and vascular oculopathy	14
Blocking the interaction between interleukin-17A and endoplasmic reticulum stress in macrophage attenuates retinal neovascularization in oxygen-induced retinopathy	14
VHL Ser65 mutations enhance HIF2α signaling and promote epithelial-mesenchymal transition of renal cancer cells	13
ISL1 controls pancreatic alpha cell fate and beta cell maturation	13
Overview of the meningeal lymphatic vessels in aging and central nervous system disorders	13
In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-κB modulator in lung cancer	13
Spatiotemporal control of genome engineering in cone photoreceptors	13
PFKFB3 in neovascular eye disease: unraveling mechanisms and exploring therapeutic strategies	13
Phosphorylation at tyrosine 317 and 508 are crucial for PIK3CA/p110α to promote CRC tumorigenesis	13
Lack of basic rationale in epithelial-mesenchymal transition and its related concepts	13
Presenilin-1 F105C mutation leads to tau accumulation in human neurons via the Akt/mTORC1 signaling pathway	13
The balance between NANOG and SOX17 mediated by TET proteins regulates specification of human primordial germ cell fate	13
Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake	13
Golgiphagy: a novel selective autophagy to the fore	13
Blockade of the Arid5a/IL-6/STAT3 axis underlies the anti-inflammatory effect of Rbpjl in acute pancreatitis	13
Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing	13
Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma	13
Arcuate AgRP, but not POMC neurons, modulate paraventricular CRF synthesis and release in response to fasting	13
Functions and mechanisms of protein disulfide isomerase family in cancer emergence	13
Retraction Note: The suppressing role of miR-622 in renal cell carcinoma progression by down-regulation of CCL18/MAPK signal pathway	13
Chemical screen in zebrafish lateral line identified compounds that ameliorate neomycin-induced ototoxicity by inhibiting ferroptosis pathway	13
GLUT1-mediated microglial proinflammatory activation contributes to the development of stress-induced spatial learning and memory dysfunction in mice	13
A neonatal rat model of pulmonary vein stenosis	13