Scientific Reports

Article	Citations
Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study	3650
COVID-Net: a tailored deep convolutional neural network design for detection of COVID-19 cases from chest X-ray images	1367
Management of validation of HPLC method for determination of acetylsalicylic acid impurities in a new pharmaceutical product	1260
More than 50 long-term effects of COVID-19: a systematic review and meta-analysis	1208
The COVID-19 social media infodemic	1093
Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025	814
Pancancer survival analysis of cancer hallmark genes	596
Application of subject-specific adaptive mechanical loading for bone healing in a mouse tail vertebral defect	595
Federated learning in medicine: facilitating multi-institutional collaborations without sharing patient data	497
Climate change impact on flood and extreme precipitation increases with water availability	413
Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronaviruses	402
AMRFinderPlus and the Reference Gene Catalog facilitate examination of the genomic links among antimicrobial resistance, stress response, and virulence	396
Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care	375
The same chemical state of carbon gives rise to two peaks in X-ray photoelectron spectroscopy	356
Green route to synthesize Zinc Oxide Nanoparticles using leaf extracts of Cassia fistula and Melia azadarach and their antibacterial potential	333
Global prevalence of mental health issues among the general population during the coronavirus disease-2019 pandemic: a systematic review and meta-analysis	327
Physical activity and screen time of children and adolescents before and during the COVID-19 lockdown in Germany: a natural experiment	315
Potential toxicity of polystyrene microplastic particles	306
VolcaNoseR is a web app for creating, exploring, labeling and sharing volcano plots	294
Projections of global-scale extreme sea levels and resulting episodic coastal flooding over the 21st Century	280
Levels of heavy metals in wastewater and soil samples from open drainage channels in Nairobi, Kenya: community health implication	277
Efficacy of masks and face coverings in controlling outward aerosol particle emission from expiratory activities	271
Brain tumor segmentation based on deep learning and an attention mechanism using MRI multi-modalities brain images	263
Green synthesis of silver nanoparticles using Lysiloma acapulcensis exhibit high-antimicrobial activity	261
Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition	261

In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication	258
Causes of death and comorbidities in hospitalized patients with COVID-19	254
Mapping the NFT revolution: market trends, trade networks, and visual features	253
Multimodal deep learning models for early detection of Alzheimer’s disease stage	253
A new nickel-based co-crystal complex electrocatalyst amplified by NiO dope Pt nanostructure hybrid; a highly sensitive approach for determination of cysteamine in the presence of serotonin	238
Global trends in antimicrobial use in aquaculture	231
Angiogenesis Analyzer for ImageJ — A comparative morphometric analysis of “Endothelial Tube Formation Assay” and “Fibrin Bead Assay”	226
Analyzing trend and forecasting of rainfall changes in India using non-parametrical and machine learning approaches	226
Genome-wide analysis of SARS-CoV-2 virus strains circulating worldwide implicates heterogeneity	218
Estimating worldwide effects of non-pharmaceutical interventions on COVID-19 incidence and population mobility patterns using a multiple-event study	217
Developing a prediction model to estimate the true burden of respiratory syncytial virus (RSV) in hospitalised children in Western Australia	212
Comparison between 16S rRNA and shotgun sequencing data for the taxonomic characterization of the gut microbiota	206
The effect of social media on well-being differs from adolescent to adolescent	206
Increased future occurrences of the exceptional 2018–2019 Central European drought under global warming	206
Long-COVID in children and adolescents: a systematic review and meta-analyses	204
Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides	202
Mechanistic understanding of the adsorption and thermodynamic aspects of cationic methylene blue dye onto cellulosic olive stones biomass from wastewater	199
A candidate multi-epitope vaccine against SARS-CoV-2	196
Explaining among-country variation in COVID-19 case fatality rate	194
Analysis of vitamin D level among asymptomatic and critically ill COVID-19 patients and its correlation with inflammatory markers	193
Dynamics of the ACE2–SARS-CoV-2/SARS-CoV spike protein interface reveal unique mechanisms	190
Machine learning prediction in cardiovascular diseases: a meta-analysis	189
UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication	187
The emerging role of neutrophil extracellular traps in severe acute respiratory syndrome coronavirus 2 (COVID-19)	183
The actual 5-year survivors of pancreatic ductal adenocarcinoma based on real-world data	179
Plant growth promoting rhizobacteria alleviates drought stress in potato in response to suppressive oxidative stress and antioxidant enzymes activities	179
Second wave COVID-19 pandemics in Europe: a temporal playbook	179
Epidemiology and outcomes of COVID-19 in HIV-infected individuals: a systematic review and meta-analysis	177
The efficacy and safety of Favipiravir in treatment of COVID-19: a systematic review and meta-analysis of clinical trials	174
COVID-19 image classification using deep features and fractional-order marine predators algorithm	174
The developmental trajectories of executive function from adolescence to old age	173
A systematic review and meta-analysis of geographic differences in comorbidities and associated severity and mortality among individuals with COVID-19	173
Early detection of type 2 diabetes mellitus using machine learning-based prediction models	171
Novel approach for effective removal of methylene blue dye from water using fava bean peel waste	170
Gut microbiota markers associated with obesity and overweight in Italian adults	170
Associations between green/blue spaces and mental health across 18 countries	169
The removal of anionic and cationic dyes from an aqueous solution using biomass-based activated carbon	168
Non-compulsory measures sufficiently reduced human mobility in Tokyo during the COVID-19 epidemic	167
Systematic review of the epidemiology of acne vulgaris	166
Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide	164
Tomato detection based on modified YOLOv3 framework	164
Electrospun cellulose acetate/gelatin nanofibrous wound dressing containing berberine for diabetic foot ulcer healing: in vitro and in vivo studies	162
BEHRT: Transformer for Electronic Health Records	162
Deep learning-based model for detecting 2019 novel coronavirus pneumonia on high-resolution computed tomography	162
Perceived stress as mediator for longitudinal effects of the COVID-19 lockdown on wellbeing of parents and children	162
Effect of glycerol plasticizer loading on the physical, mechanical, thermal, and barrier properties of arrowroot (Maranta arundinacea) starch biopolymers	161
Hesperidin Loaded on Gold Nanoparticles as a Drug Delivery System for a Successful Biocompatible, Anti-Cancer, Anti-Inflammatory and Phagocytosis Inducer Model	161
Molecular docking study of potential phytochemicals and their effects on the complex of SARS-CoV2 spike protein and human ACE2	160
Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: a combinational approach for enhanced delivery of nanoparticles	158
Validating a functional near-infrared spectroscopy diagnostic paradigm for Major Depressive Disorder	158

Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis	158
Refractive index gas sensor based on the Tamm state in a one-dimensional photonic crystal: Theoretical optimisation	158
Assessing magnetic and inductive thermal properties of various surfactants functionalised Fe3O4 nanoparticles for hyperthermia	158
Photocatalytic dye degradation and antimicrobial activities of Pure and Ag-doped ZnO using Cannabis sativa leaf extract	157
Coupling machine learning and crop modeling improves crop yield prediction in the US Corn Belt	157
Covid-19 mortality is negatively associated with test number and government effectiveness	156
Plasma tissue plasminogen activator and plasminogen activator inhibitor-1 in hospitalized COVID-19 patients	155
Drivers and impacts of the most extreme marine heatwave events	154
Comparing the clinical efficacy of COVID-19 vaccines: a systematic review and network meta-analysis	154
Deep learning-based landslide susceptibility mapping	152
Global trends in mangrove forest fragmentation	152
On evaluation metrics for medical applications of artificial intelligence	152
Temporal Convolutional Networks for the Advance Prediction of ENSO	152
Development of a polyvinyl alcohol/sodium alginate hydrogel-based scaffold incorporating bFGF-encapsulated microspheres for accelerated wound healing	150
Longer-term (≥ 2 years) survival in patients with glioblastoma in population-based studies pre- and post-2005: a systematic review and meta-analysis	150
3D bioprinting of cells, tissues and organs	146
Forest aboveground biomass estimation using Landsat 8 and Sentinel-1A data with machine learning algorithms	146
The Coronavirus Health and Impact Survey (CRISIS) reveals reproducible correlates of pandemic-related mood states across the Atlantic	145
Long-distance airborne dispersal of SARS-CoV-2 in COVID-19 wards	145
A chain mediation model on COVID-19 symptoms and mental health outcomes in Americans, Asians and Europeans	145
The impact of the COVID-19 pandemic on wellbeing and cognitive functioning of older adults	144
The fingerprints of climate warming on cereal crops phenology and adaptation options	144
Secondary bacterial infection in COVID-19 patients is a stronger predictor for death compared to influenza patients	143
Experimental comparison between ZnO and MoS2 nanoparticles as additives on performance of diesel oil-based nano lubricant	143
Antibacterial action and target mechanisms of zinc oxide nanoparticles against bacterial pathogens	142
The impact of facemasks on emotion recognition, trust attribution and re-identification	141
Toxic and heavy metals contamination assessment in soil and water to evaluate human health risk	140
Standardization of brain MR images across machines and protocols: bridging the gap for MRI-based radiomics	140
Green synthesis of selenium nanoparticles mediated from Ceropegia bulbosa Roxb extract and its cytotoxicity, antimicrobial, mosquitocidal and photocatalytic activities	140
Bifidobacterium adolescentis as a key member of the human gut microbiota in the production of GABA	140
Microplastics in fish and fishmeal: an emerging environmental challenge?	139
Development of CpG-adjuvanted stable prefusion SARS-CoV-2 spike antigen as a subunit vaccine against COVID-19	138
Cell Atlas of The Human Fovea and Peripheral Retina	138
Silver nanoparticle conductive inks: synthesis, characterization, and fabrication of inkjet-printed flexible electrodes	136
Sea-level rise exponentially increases coastal flood frequency	136
Global prevalence and distribution of vancomycin resistant, vancomycin intermediate and heterogeneously vancomycin intermediate Staphylococcus aureus clinical isolates: a systematic review and meta-an	136
Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2	135
Comparative performance analysis of K-nearest neighbour (KNN) algorithm and its different variants for disease prediction	134
Years of life lost to COVID-19 in 81 countries	133
No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor	133
Machine learning prediction for mortality of patients diagnosed with COVID-19: a nationwide Korean cohort study	133
Limits in the detection of m6A changes using MeRIP/m6A-seq	132
Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients	132
Comparison of gut microbiota in exclusively breast-fed and formula-fed babies: a study of 91 term infants	131
Selenium and silica nanostructure-based recovery of strawberry plants subjected to drought stress	131
Global Prevalence and Risk Factors of Gastro-oesophageal Reflux Disease (GORD): Systematic Review with Meta-analysis	130
Antibacterial activity and characteristics of silver nanoparticles biosynthesized from Carduus crispus	130
Numerical investigation for rotating flow of MHD hybrid nanofluid with thermal radiation over a stretching sheet	128
Increased likelihood of heat-induced large wildfires in the Mediterranean Basin	128
ZnO size and shape effect on antibacterial activity and cytotoxicity profile	127
Effects of water absorption on the mechanical properties of hybrid natural fibre/phenol formaldehyde composites	127
Clinical characterization of dysautonomia in long COVID-19 patients	126
Neutrophil-to-lymphocyte ratio and mortality in the United States general population	126
A first principles investigation on the structural, mechanical, electronic, and catalytic properties of biphenylene	126
A multilayer multimodal detection and prediction model based on explainable artificial intelligence for Alzheimer’s disease	126
On the widespread enhancement in fine particulate matter across the Indo-Gangetic Plain towards winter	125
Fabrication of monodispersed copper oxide nanoparticles with potential application as antimicrobial agents	125
Biosynthesis and characterization of gold nanoparticles using Brazilian red propolis and evaluation of its antimicrobial and anticancer activities	125
Device simulation of highly efficient eco-friendly CH3NH3SnI3 perovskite solar cell	124
Low-cost portable microwave sensor for non-invasive monitoring of blood glucose level: novel design utilizing a four-cell CSRR hexagonal configuration	124
Fully automatic wound segmentation with deep convolutional neural networks	123
Adsorption capability of brewed tea waste in waters containing toxic lead(II), cadmium (II), nickel (II), and zinc(II) heavy metal ions	121
3D Printing of Inertial Microfluidic Devices	120
Management strategies in a SEIR-type model of COVID 19 community spread	120
Padina boryana mediated green synthesis of crystalline palladium nanoparticles as potential nanodrug against multidrug resistant bacteria and cancer cells	119
Simple rapid stabilization method through citric acid modification for magnetite nanoparticles	119
Quantifying greenhouse gas emissions from global aquaculture	118
A comparison of machine learning methods for survival analysis of high-dimensional clinical data for dementia prediction	118
Explainable machine learning can outperform Cox regression predictions and provide insights in breast cancer survival	118
Low HDL and high triglycerides predict COVID-19 severity	117
Mutations introduced in susceptibility genes through CRISPR/Cas9 genome editing confer increased late blight resistance in potatoes	117
Finding Plastic Patches in Coastal Waters using Optical Satellite Data	117
Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation	117
Explainable identification and mapping of trees using UAV RGB image and deep learning	117
Emerging MDR-Pseudomonas aeruginosa in fish commonly harbor oprL and toxA virulence genes and blaTEM, blaCTX-M, and tetA antibiotic-resistance genes	117
CINENet: deep learning-based 3D cardiac CINE MRI reconstruction with multi-coil complex-valued 4D spatio-temporal convolutions	117
Microplastic pollution in seawater and marine organisms across the Tropical Eastern Pacific and Galápagos	117
Grindability of carbon fiber reinforced polymer using CNT biological lubricant	116
Modeling, state estimation, and optimal control for the US COVID-19 outbreak	116
Smart textiles for multimodal wearable sensing using highly stretchable multiplexed optical fiber system	116

Biodegradable carboxymethyl cellulose based material for sustainable packaging application	116
An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study	115
The COVID-19 pandemic masks the way people perceive faces	114
Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice	114
Weakly-supervised learning for lung carcinoma classification using deep learning	114
Effect of heat input on interfacial characterization of the butter joint of hot-rolling CP-Ti/Q235 bimetallic sheets by Laser + CMT	114
From graphene oxide towards aminated graphene: facile synthesis, its structure and electronic properties	114
Drought characteristics and its elevation dependence in the Qinghai–Tibet plateau during the last half-century	114
Phytochemical and antioxidant analysis of medicinal and food plants towards bioactive food and pharmaceutical resources	114
Stability of SARS-CoV-2 on critical personal protective equipment	114
The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV	113
Marine heatwaves exacerbate climate change impacts for fisheries in the northeast Pacific	113
Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition	113
Green copper oxide nanoparticles for lead, nickel, and cadmium removal from contaminated water	113
Gut metagenomic and short chain fatty acids signature in hypertension: a cross-sectional study	113
Recent advances in removal of Congo Red dye by adsorption using an industrial waste	112
Performance comparison of modified ComBat for harmonization of radiomic features for multicenter studies	112
Effects of salicylic acid, zinc and glycine betaine on morpho-physiological growth and yield of maize under drought stress	112
Structure based pharmacophore modeling, virtual screening, molecular docking and ADMET approaches for identification of natural anti-cancer agents targeting XIAP protein	111
Urban and air pollution: a multi-city study of long-term effects of urban landscape patterns on air quality trends	110
Impact of meteorological conditions and air pollution on COVID-19 pandemic transmission in Italy	110
The rhizosphere microbiome plays a role in the resistance to soil-borne pathogens and nutrient uptake of strawberry cultivars under field conditions	109
Synergistic effects of combinatorial chitosan and polyphenol biomolecules on enhanced antibacterial activity of biofunctionalized silver nanoparticles	109
Survival of the enveloped bacteriophage Phi6 (a surrogate for SARS-CoV-2) in evaporated saliva microdroplets deposited on glass surfaces	109
Bone marrow-derived mesenchymal stem cells improve cognitive impairment in an Alzheimer’s disease model by increasing the expression of microRNA-146a in hippocampus	109
Meta-analysis on how manure application changes soil organic carbon storage	108
Risk attitudes and human mobility during the COVID-19 pandemic	108
Modeling and forecasting the early evolution of the Covid-19 pandemic in Brazil	108
Inefficiency of SIR models in forecasting COVID-19 epidemic: a case study of Isfahan	108
Trait and state anxiety are mapped differently in the human brain	107
Prevalence of primary open angle glaucoma in the last 20 years: a meta-analysis and systematic review	107
Mental health prevalence and predictors among university students in nine countries during the COVID-19 pandemic: a cross-national study	107
Comprehensive transcriptomic analysis of COVID-19 blood, lung, and airway	107
MapReduce-based big data classification model using feature subset selection and hyperparameter tuned deep belief network	107
African soil properties and nutrients mapped at 30 m spatial resolution using two-scale ensemble machine learning	107
Ecofriendly biodegradation of Reactive Black 5 by newly isolated Sterigmatomyces halophilus SSA1575, valued for textile azo dye wastewater processing and detoxification	107
Deep Learning Hybrid Method to Automatically Diagnose Periodontal Bone Loss and Stage Periodontitis	106
A novel Cuproptosis-related LncRNA signature to predict prognosis in hepatocellular carcinoma	106
Development and large volume production of extremely high current density YBa2Cu3O7 superconducting wires for fusion	106
Ecosystem response persists after a prolonged marine heatwave	106
High yield synthesis of graphene quantum dots from biomass waste as a highly selective probe for Fe3+ sensing	106
Optimization of cell viability assays to improve replicability and reproducibility of cancer drug sensitivity screens	106
Streamflow prediction using an integrated methodology based on convolutional neural network and long short-term memory networks	106
An extensive study on multiple ETL and HTL layers to design and simulation of high-performance lead-free CsSnCl3-based perovskite solar cells	106
The potential land requirements and related land use change emissions of solar energy	106
COVID-19 diagnosis by routine blood tests using machine learning	105
Characterizing the Qatar advanced-phase SARS-CoV-2 epidemic	105
Concentrations and sources of heavy metals in shallow sediments in Lake Bafa, Turkey	105
Investigating the optimum size of nanoparticles for their delivery into the brain assisted by focused ultrasound-induced blood–brain barrier opening	105
A comprehensive study on classification of COVID-19 on computed tomography with pretrained convolutional neural networks	104
Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection	104
Variability and reproducibility in deep learning for medical image segmentation	104
Transatlantic spread of highly pathogenic avian influenza H5N1 by wild birds from Europe to North America in 2021	104
Long-term monitoring of SARS-CoV-2 RNA in wastewater of the Frankfurt metropolitan area in Southern Germany	104
The consequences of COVID-19 on social interactions: an online study on face covering	104
Ascorbate oxidation by iron, copper and reactive oxygen species: review, model development, and derivation of key rate constants	103
Pore-scale modelling and sensitivity analyses of hydrogen-brine multiphase flow in geological porous media	103
Measurement of excitation-inhibition ratio in autism spectrum disorder using critical brain dynamics	103
Rapid production of SARS-CoV-2 receptor binding domain (RBD) and spike specific monoclonal antibody CR3022 in Nicotiana benthamiana	103
Morphometry of SARS-CoV and SARS-CoV-2 particles in ultrathin plastic sections of infected Vero cell cultures	102
Comparing different deep learning architectures for classification of chest radiographs	102
Cost effective liquid phase exfoliation of MoS2 nanosheets and photocatalytic activity for wastewater treatment enforced by visible light	102
Metabolic alterations in Parkinson’s disease astrocytes	102
Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19	102
First evidence of plastic fallout from the North Pacific Garbage Patch	102
Rational approach toward COVID-19 main protease inhibitors via molecular docking, molecular dynamics simulation and free energy calculation	102
Fragmentation of plastic objects in a laboratory seawater microcosm	102
The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism	102
Fully Spray-Coated Triple-Cation Perovskite Solar Cells	102
Rapid fragmentation of microplastics by the freshwater amphipod Gammarus duebeni (Lillj.)	101
Anthropogenic drought dominates groundwater depletion in Iran	101
Evaluation of spatial-temporal variation performance of ERA5 precipitation data in China	101
Role of M1-polarized tumor-associated macrophages in the prognosis of advanced ovarian cancer patients	101
A cognitive profile of multi-sensory imagery, memory and dreaming in aphantasia	101
ssGSEA score-based Ras dependency indexes derived from gene expression data reveal potential Ras addiction mechanisms with possible clinical implications	100
Enhanced photocatalytic degradation of Acid Blue dye using CdS/TiO2 nanocomposite	100
Systematic comparison and assessment of RNA-seq procedures for gene expression quantitative analysis	100
Probiotics have beneficial metabolic effects in patients with type 2 diabetes mellitus: a meta-analysis of randomized clinical trials	99
Exploring the relationship between air pollution and meteorological conditions in China under environmental governance	99
Spatiotemporal drought analysis by the standardized precipitation index (SPI) and standardized precipitation evapotranspiration index (SPEI) in Sichuan Province, China	99
Rearing substrate impacts growth and macronutrient composition of Hermetia illucens (L.) (Diptera: Stratiomyidae) larvae produced at an industrial scale	98
COVID-19-mandated social restrictions unveil the impact of social time pressure on sleep and body clock	98
Transfer learning for ECG classification	98
Walnut shell powder as a low-cost adsorbent for methylene blue dye: isotherm, kinetics, thermodynamic, desorption and response surface methodology examinations	98
The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals	98
The incidence and clinical analysis of non-melanoma skin cancer	98
Non-invasive continuous-time glucose monitoring system using a chipless printable sensor based on split ring microwave resonators	97
Bidirectional association between periodontal disease and diabetes mellitus: a systematic review and meta-analysis of cohort studies	97
Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies	97
Facile one-pot green synthesis of Ag–ZnO Nanocomposites using potato peeland their Ag concentration dependent photocatalytic properties	97
Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential?	97
Spatial and temporal variations of air pollution over 41 cities of India during the COVID-19 lockdown period	97
Microplastics accumulate fungal pathogens in terrestrial ecosystems	97
Elliptical metallic rings-shaped fractal metamaterial absorber in the visible regime	97
Patents and intellectual property assets as non-fungible tokens; key technologies and challenges	97