Scientific Reports

Article	Citations
Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study	3834
COVID-Net: a tailored deep convolutional neural network design for detection of COVID-19 cases from chest X-ray images	1432
Management of validation of HPLC method for determination of acetylsalicylic acid impurities in a new pharmaceutical product	1385
More than 50 long-term effects of COVID-19: a systematic review and meta-analysis	1295
The COVID-19 social media infodemic	1143
Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025	865
Application of subject-specific adaptive mechanical loading for bone healing in a mouse tail vertebral defect	624
Pancancer survival analysis of cancer hallmark genes	624
Federated learning in medicine: facilitating multi-institutional collaborations without sharing patient data	538
Climate change impact on flood and extreme precipitation increases with water availability	479
AMRFinderPlus and the Reference Gene Catalog facilitate examination of the genomic links among antimicrobial resistance, stress response, and virulence	475
The same chemical state of carbon gives rise to two peaks in X-ray photoelectron spectroscopy	391
Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care	381
Global prevalence of mental health issues among the general population during the coronavirus disease-2019 pandemic: a systematic review and meta-analysis	353
Physical activity and screen time of children and adolescents before and during the COVID-19 lockdown in Germany: a natural experiment	333
VolcaNoseR is a web app for creating, exploring, labeling and sharing volcano plots	332
Brain tumor segmentation based on deep learning and an attention mechanism using MRI multi-modalities brain images	306
Projections of global-scale extreme sea levels and resulting episodic coastal flooding over the 21st Century	301
Green synthesis of silver nanoparticles using Lysiloma acapulcensis exhibit high-antimicrobial activity	284
Multimodal deep learning models for early detection of Alzheimer’s disease stage	281
Efficacy of masks and face coverings in controlling outward aerosol particle emission from expiratory activities	281
Mapping the NFT revolution: market trends, trade networks, and visual features	277
Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition	277
Causes of death and comorbidities in hospitalized patients with COVID-19	267
In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication	264

Global trends in antimicrobial use in aquaculture	257
Angiogenesis Analyzer for ImageJ — A comparative morphometric analysis of “Endothelial Tube Formation Assay” and “Fibrin Bead Assay”	252
A new nickel-based co-crystal complex electrocatalyst amplified by NiO dope Pt nanostructure hybrid; a highly sensitive approach for determination of cysteamine in the presence of serotonin	241
Developing a prediction model to estimate the true burden of respiratory syncytial virus (RSV) in hospitalised children in Western Australia	236
Long-COVID in children and adolescents: a systematic review and meta-analyses	236
Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides	230
Comparison between 16S rRNA and shotgun sequencing data for the taxonomic characterization of the gut microbiota	229
The effect of social media on well-being differs from adolescent to adolescent	224
Genome-wide analysis of SARS-CoV-2 virus strains circulating worldwide implicates heterogeneity	220
Estimating worldwide effects of non-pharmaceutical interventions on COVID-19 incidence and population mobility patterns using a multiple-event study	220
Increased future occurrences of the exceptional 2018–2019 Central European drought under global warming	219
Mechanistic understanding of the adsorption and thermodynamic aspects of cationic methylene blue dye onto cellulosic olive stones biomass from wastewater	219
Machine learning prediction in cardiovascular diseases: a meta-analysis	210
On evaluation metrics for medical applications of artificial intelligence	207
A candidate multi-epitope vaccine against SARS-CoV-2	206
Plant growth promoting rhizobacteria alleviates drought stress in potato in response to suppressive oxidative stress and antioxidant enzymes activities	204
UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication	201
Explaining among-country variation in COVID-19 case fatality rate	200
Analysis of vitamin D level among asymptomatic and critically ill COVID-19 patients and its correlation with inflammatory markers	198
The actual 5-year survivors of pancreatic ductal adenocarcinoma based on real-world data	198
The developmental trajectories of executive function from adolescence to old age	194
Dynamics of the ACE2–SARS-CoV-2/SARS-CoV spike protein interface reveal unique mechanisms	192
Assessing magnetic and inductive thermal properties of various surfactants functionalised Fe3O4 nanoparticles for hyperthermia	190
Associations between green/blue spaces and mental health across 18 countries	189
Early detection of type 2 diabetes mellitus using machine learning-based prediction models	187
The emerging role of neutrophil extracellular traps in severe acute respiratory syndrome coronavirus 2 (COVID-19)	187
Effect of glycerol plasticizer loading on the physical, mechanical, thermal, and barrier properties of arrowroot (Maranta arundinacea) starch biopolymers	187
A systematic review and meta-analysis of geographic differences in comorbidities and associated severity and mortality among individuals with COVID-19	186
The removal of anionic and cationic dyes from an aqueous solution using biomass-based activated carbon	185
Second wave COVID-19 pandemics in Europe: a temporal playbook	184
Epidemiology and outcomes of COVID-19 in HIV-infected individuals: a systematic review and meta-analysis	183
The efficacy and safety of Favipiravir in treatment of COVID-19: a systematic review and meta-analysis of clinical trials	183
COVID-19 image classification using deep features and fractional-order marine predators algorithm	182
Gut microbiota markers associated with obesity and overweight in Italian adults	181
Antibacterial action and target mechanisms of zinc oxide nanoparticles against bacterial pathogens	180
Toxic and heavy metals contamination assessment in soil and water to evaluate human health risk	179
Deep learning-based model for detecting 2019 novel coronavirus pneumonia on high-resolution computed tomography	176
Deep learning-based landslide susceptibility mapping	176
Coupling machine learning and crop modeling improves crop yield prediction in the US Corn Belt	176
Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis	173
Drivers and impacts of the most extreme marine heatwave events	172
Tomato detection based on modified YOLOv3 framework	172
Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: a combinational approach for enhanced delivery of nanoparticles	172
Non-compulsory measures sufficiently reduced human mobility in Tokyo during the COVID-19 epidemic	171
Perceived stress as mediator for longitudinal effects of the COVID-19 lockdown on wellbeing of parents and children	168
Comparative performance analysis of K-nearest neighbour (KNN) algorithm and its different variants for disease prediction	167
Molecular docking study of potential phytochemicals and their effects on the complex of SARS-CoV2 spike protein and human ACE2	165
3D bioprinting of cells, tissues and organs	164
Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide	164
Longer-term (≥ 2 years) survival in patients with glioblastoma in population-based studies pre- and post-2005: a systematic review and meta-analysis	163

Comparing the clinical efficacy of COVID-19 vaccines: a systematic review and network meta-analysis	163
Covid-19 mortality is negatively associated with test number and government effectiveness	161
The fingerprints of climate warming on cereal crops phenology and adaptation options	160
Bifidobacterium adolescentis as a key member of the human gut microbiota in the production of GABA	157
Plasma tissue plasminogen activator and plasminogen activator inhibitor-1 in hospitalized COVID-19 patients	157
ZnO size and shape effect on antibacterial activity and cytotoxicity profile	157
Standardization of brain MR images across machines and protocols: bridging the gap for MRI-based radiomics	155
Antibacterial activity and characteristics of silver nanoparticles biosynthesized from Carduus crispus	155
Green synthesis of selenium nanoparticles mediated from Ceropegia bulbosa Roxb extract and its cytotoxicity, antimicrobial, mosquitocidal and photocatalytic activities	155
The Coronavirus Health and Impact Survey (CRISIS) reveals reproducible correlates of pandemic-related mood states across the Atlantic	155
Secondary bacterial infection in COVID-19 patients is a stronger predictor for death compared to influenza patients	154
Microplastics in fish and fishmeal: an emerging environmental challenge?	154
Comparison of gut microbiota in exclusively breast-fed and formula-fed babies: a study of 91 term infants	151
Global prevalence and distribution of vancomycin resistant, vancomycin intermediate and heterogeneously vancomycin intermediate Staphylococcus aureus clinical isolates: a systematic review and meta-an	151
The impact of the COVID-19 pandemic on wellbeing and cognitive functioning of older adults	151
The impact of facemasks on emotion recognition, trust attribution and re-identification	150
Long-distance airborne dispersal of SARS-CoV-2 in COVID-19 wards	149
A chain mediation model on COVID-19 symptoms and mental health outcomes in Americans, Asians and Europeans	148
Neutrophil-to-lymphocyte ratio and mortality in the United States general population	145
A first principles investigation on the structural, mechanical, electronic, and catalytic properties of biphenylene	145
An extensive study on multiple ETL and HTL layers to design and simulation of high-performance lead-free CsSnCl3-based perovskite solar cells	143
Selenium and silica nanostructure-based recovery of strawberry plants subjected to drought stress	143
Low-cost portable microwave sensor for non-invasive monitoring of blood glucose level: novel design utilizing a four-cell CSRR hexagonal configuration	142
Transatlantic spread of highly pathogenic avian influenza H5N1 by wild birds from Europe to North America in 2021	142
Fabrication of monodispersed copper oxide nanoparticles with potential application as antimicrobial agents	142
Numerical investigation for rotating flow of MHD hybrid nanofluid with thermal radiation over a stretching sheet	142
Years of life lost to COVID-19 in 81 countries	141
Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2	141
Development of CpG-adjuvanted stable prefusion SARS-CoV-2 spike antigen as a subunit vaccine against COVID-19	141
Microplastic pollution in seawater and marine organisms across the Tropical Eastern Pacific and Galápagos	140
Increased likelihood of heat-induced large wildfires in the Mediterranean Basin	140
Device simulation of highly efficient eco-friendly CH3NH3SnI3 perovskite solar cell	140
A multilayer multimodal detection and prediction model based on explainable artificial intelligence for Alzheimer’s disease	140
Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients	139
Machine learning prediction for mortality of patients diagnosed with COVID-19: a nationwide Korean cohort study	139
Recent advances in removal of Congo Red dye by adsorption using an industrial waste	137
Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice	135
Phytochemical and antioxidant analysis of medicinal and food plants towards bioactive food and pharmaceutical resources	135
No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor	134
Clinical characterization of dysautonomia in long COVID-19 patients	133
Effects of water absorption on the mechanical properties of hybrid natural fibre/phenol formaldehyde composites	133
Biodegradable carboxymethyl cellulose based material for sustainable packaging application	132
Biosynthesis and characterization of gold nanoparticles using Brazilian red propolis and evaluation of its antimicrobial and anticancer activities	132
Quantifying greenhouse gas emissions from global aquaculture	131
Explainable identification and mapping of trees using UAV RGB image and deep learning	131
Explainable machine learning can outperform Cox regression predictions and provide insights in breast cancer survival	130
High yield synthesis of graphene quantum dots from biomass waste as a highly selective probe for Fe3+ sensing	130
Meta-analysis on how manure application changes soil organic carbon storage	129
Padina boryana mediated green synthesis of crystalline palladium nanoparticles as potential nanodrug against multidrug resistant bacteria and cancer cells	129
An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study	129
Simple rapid stabilization method through citric acid modification for magnetite nanoparticles	128
Fully automatic wound segmentation with deep convolutional neural networks	128
Effect of heat input on interfacial characterization of the butter joint of hot-rolling CP-Ti/Q235 bimetallic sheets by Laser + CMT	127
Mutations introduced in susceptibility genes through CRISPR/Cas9 genome editing confer increased late blight resistance in potatoes	127
CINENet: deep learning-based 3D cardiac CINE MRI reconstruction with multi-coil complex-valued 4D spatio-temporal convolutions	127
Adsorption capability of brewed tea waste in waters containing toxic lead(II), cadmium (II), nickel (II), and zinc(II) heavy metal ions	127
Streamflow prediction using an integrated methodology based on convolutional neural network and long short-term memory networks	126
Urban and air pollution: a multi-city study of long-term effects of urban landscape patterns on air quality trends	126
Low HDL and high triglycerides predict COVID-19 severity	124
Emerging MDR-Pseudomonas aeruginosa in fish commonly harbor oprL and toxA virulence genes and blaTEM, blaCTX-M, and tetA antibiotic-resistance genes	124
African soil properties and nutrients mapped at 30 m spatial resolution using two-scale ensemble machine learning	124
Management strategies in a SEIR-type model of COVID 19 community spread	123
A comparison of machine learning methods for survival analysis of high-dimensional clinical data for dementia prediction	123
Modeling, state estimation, and optimal control for the US COVID-19 outbreak	122
Structure based pharmacophore modeling, virtual screening, molecular docking and ADMET approaches for identification of natural anti-cancer agents targeting XIAP protein	122
Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation	122
Green copper oxide nanoparticles for lead, nickel, and cadmium removal from contaminated water	121
Effects of salicylic acid, zinc and glycine betaine on morpho-physiological growth and yield of maize under drought stress	121
Synergistic effects of combinatorial chitosan and polyphenol biomolecules on enhanced antibacterial activity of biofunctionalized silver nanoparticles	120
Trait and state anxiety are mapped differently in the human brain	120
Ascorbate oxidation by iron, copper and reactive oxygen species: review, model development, and derivation of key rate constants	120
Investigating the optimum size of nanoparticles for their delivery into the brain assisted by focused ultrasound-induced blood–brain barrier opening	119
Grindability of carbon fiber reinforced polymer using CNT biological lubricant	119
Ecofriendly biodegradation of Reactive Black 5 by newly isolated Sterigmatomyces halophilus SSA1575, valued for textile azo dye wastewater processing and detoxification	119
Mental health prevalence and predictors among university students in nine countries during the COVID-19 pandemic: a cross-national study	118
The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV	118
The potential land requirements and related land use change emissions of solar energy	118
Smart textiles for multimodal wearable sensing using highly stretchable multiplexed optical fiber system	118
Bone marrow-derived mesenchymal stem cells improve cognitive impairment in an Alzheimer’s disease model by increasing the expression of microRNA-146a in hippocampus	118
Drought characteristics and its elevation dependence in the Qinghai–Tibet plateau during the last half-century	118

Stability of SARS-CoV-2 on critical personal protective equipment	118
Ecosystem response persists after a prolonged marine heatwave	117
The COVID-19 pandemic masks the way people perceive faces	117
The rhizosphere microbiome plays a role in the resistance to soil-borne pathogens and nutrient uptake of strawberry cultivars under field conditions	117
Prisoner’s dilemma game model Based on historical strategy information	117
Evaluation of spatial-temporal variation performance of ERA5 precipitation data in China	117
Prevalence of primary open angle glaucoma in the last 20 years: a meta-analysis and systematic review	117
Pore-scale modelling and sensitivity analyses of hydrogen-brine multiphase flow in geological porous media	116
Enhanced photocatalytic degradation of Acid Blue dye using CdS/TiO2 nanocomposite	116
Federated learning and differential privacy for medical image analysis	116
Spatiotemporal drought analysis by the standardized precipitation index (SPI) and standardized precipitation evapotranspiration index (SPEI) in Sichuan Province, China	116
A novel Cuproptosis-related LncRNA signature to predict prognosis in hepatocellular carcinoma	115
Modeling and forecasting the early evolution of the Covid-19 pandemic in Brazil	115
Survival of the enveloped bacteriophage Phi6 (a surrogate for SARS-CoV-2) in evaporated saliva microdroplets deposited on glass surfaces	115
Development and large volume production of extremely high current density YBa2Cu3O7 superconducting wires for fusion	114
Microplastics accumulate fungal pathogens in terrestrial ecosystems	114
Concentrations and sources of heavy metals in shallow sediments in Lake Bafa, Turkey	113
Anthropogenic drought dominates groundwater depletion in Iran	113
COVID-19 diagnosis by routine blood tests using machine learning	112
Inefficiency of SIR models in forecasting COVID-19 epidemic: a case study of Isfahan	112
Impact of meteorological conditions and air pollution on COVID-19 pandemic transmission in Italy	112
Variability and reproducibility in deep learning for medical image segmentation	112
Characterizing the Qatar advanced-phase SARS-CoV-2 epidemic	112
Facile one-pot green synthesis of Ag–ZnO Nanocomposites using potato peeland their Ag concentration dependent photocatalytic properties	112
Systematic comparison and assessment of RNA-seq procedures for gene expression quantitative analysis	112
Risk attitudes and human mobility during the COVID-19 pandemic	111
The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals	111
Bidirectional association between periodontal disease and diabetes mellitus: a systematic review and meta-analysis of cohort studies	111
Comprehensive transcriptomic analysis of COVID-19 blood, lung, and airway	111
Exploring the relationship between air pollution and meteorological conditions in China under environmental governance	111
Metabolic alterations in Parkinson’s disease astrocytes	110
The incidence and clinical analysis of non-melanoma skin cancer	110
Efficient-CapsNet: capsule network with self-attention routing	110
MapReduce-based big data classification model using feature subset selection and hyperparameter tuned deep belief network	110
The consequences of COVID-19 on social interactions: an online study on face covering	110
Silver decorated CeO2 nanoparticles for rapid photocatalytic degradation of textile rose bengal dye	109
Morphometry of SARS-CoV and SARS-CoV-2 particles in ultrathin plastic sections of infected Vero cell cultures	109
Patents and intellectual property assets as non-fungible tokens; key technologies and challenges	109
Deep learning classification of lung cancer histology using CT images	109
The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism	109
Rapid fragmentation of microplastics by the freshwater amphipod Gammarus duebeni (Lillj.)	108
Rearing substrate impacts growth and macronutrient composition of Hermetia illucens (L.) (Diptera: Stratiomyidae) larvae produced at an industrial scale	108
Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19	108
Fragmentation of plastic objects in a laboratory seawater microcosm	108
Polypharmacy, hospitalization, and mortality risk: a nationwide cohort study	108
Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection	108
Characterizing the mucin-degrading capacity of the human gut microbiota	107
Personal identifiability of user tracking data during observation of 360-degree VR video	107
Elliptical metallic rings-shaped fractal metamaterial absorber in the visible regime	107
A survey of clinicians on the use of artificial intelligence in ophthalmology, dermatology, radiology and radiation oncology	107
Understanding deep learning in land use classification based on Sentinel-2 time series	107
Rational approach toward COVID-19 main protease inhibitors via molecular docking, molecular dynamics simulation and free energy calculation	107
Transfer learning for ECG classification	107
Cost effective liquid phase exfoliation of MoS2 nanosheets and photocatalytic activity for wastewater treatment enforced by visible light	107
Non-invasive continuous-time glucose monitoring system using a chipless printable sensor based on split ring microwave resonators	107
Transformer neural network for protein-specific de novo drug generation as a machine translation problem	107
Effects of cadmium stress on growth and physiological characteristics of sassafras seedlings	107
Online misinformation is linked to early COVID-19 vaccination hesitancy and refusal	107
Long-term monitoring of SARS-CoV-2 RNA in wastewater of the Frankfurt metropolitan area in Southern Germany	106
Unravelling the multi-scale structure–property relationship of laser powder bed fusion processed and heat-treated AlSi10Mg	106
A global biophysical typology of mangroves and its relevance for ecosystem structure and deforestation	106
A comprehensive study on classification of COVID-19 on computed tomography with pretrained convolutional neural networks	106
Gait parameters of Parkinson’s disease compared with healthy controls: a systematic review and meta-analysis	106
In silico analysis of epitope-based vaccine candidate against tuberculosis using reverse vaccinology	105
Antibacterial activity and mechanism of plant flavonoids to gram-positive bacteria predicted from their lipophilicities	105
Different organic manure sources and NPK fertilizer on soil chemical properties, growth, yield and quality of okra	105
Hybrid nanofluid flow within the conical gap between the cone and the surface of a rotating disk	104
Plant growth promoting rhizobacteria isolated from halophytes and drought-tolerant plants: genomic characterisation and exploration of phyto-beneficial traits	104
Evaluation of plant growth promotion properties and induction of antioxidative defense mechanism by tea rhizobacteria of Darjeeling, India	104
Renal function is associated with blood neurofilament light chain level in older adults	104
Probiotics have beneficial metabolic effects in patients with type 2 diabetes mellitus: a meta-analysis of randomized clinical trials	104
Biosynthesis of CuO nanoparticles using aqueous extract of herbal tea (Stachys Lavandulifolia) flowers and evaluation of its catalytic activity	103
Comparing different deep learning architectures for classification of chest radiographs	103
COVID-19-mandated social restrictions unveil the impact of social time pressure on sleep and body clock	103
Rapid production of SARS-CoV-2 receptor binding domain (RBD) and spike specific monoclonal antibody CR3022 in Nicotiana benthamiana	103
Don’t get it or don’t spread it: comparing self-interested versus prosocial motivations for COVID-19 prevention behaviors	102
Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2	101
Simultaneously enhanced dielectric properties and through-plane thermal conductivity of epoxy composites with alumina and boron nitride nanosheets	101
New machine learning and physics-based scoring functions for drug discovery	101
M1 Macrophage and M1/M2 ratio defined by transcriptomic signatures resemble only part of their conventional clinical characteristics in breast cancer	101
Semiconducting to metallic transition with outstanding optoelectronic properties of CsSnCl3 perovskite under pressure	101
In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa	101
Global, regional, and country seroprevalence of Toxoplasma gondii in pregnant women: a systematic review, modelling and meta-analysis	100
Features of structure, magnetic state and electrodynamic performance of SrFe12−xInxO19	100
Comparing amorphous silica, short-range-ordered silicates and silicic acid species by FTIR	100
Automatic classification between COVID-19 pneumonia, non-COVID-19 pneumonia, and the healthy on chest X-ray image: combination of data augmentation methods	99
High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents	99
Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies	99
Anthropogenic nitrate in groundwater and its health risks in the view of background concentration in a semi arid area of Rajasthan, India	99
Akkermansia muciniphila uses human milk oligosaccharides to thrive in the early life conditions in vitro	98
An ab-initio study on structural, elastic, electronic, bonding, thermal, and optical properties of topological Weyl semimetal TaX (X = P, As)	98
A molecular test based on RT-LAMP for rapid, sensitive and inexpensive colorimetric detection of SARS-CoV-2 in clinical samples	98
Bulk high-entropy nitrides and carbonitrides	98
Effects of surgical face masks on cardiopulmonary parameters during steady state exercise	98
Spatial and temporal variations of air pollution over 41 cities of India during the COVID-19 lockdown period	98