OOIR: Observatory of International Research

Papers

(The TQCC of Biology of Sex Differences is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Gender-related variables for health research	113
The role of vitamin D in autoimmune diseases: could sex make the difference?	61
Sex differences in the human brain: a roadmap for more careful analysis and interpretation of a biological reality	61
Sex differences in the human metabolome	57
Estrogen receptors in pain modulation: cellular signaling	53
Thyroid hormone: sex-dependent role in nervous system regulation and disease	53
Sex differences in the immune response to acute COVID-19 respiratory tract infection	52
Shedding light on biological sex differences and microbiota–gut–brain axis: a comprehensive review of its roles in neuropsychiatric disorders	44
Why the estrous cycle matters for neuroscience	41
Sex and gender considerations in reporting guidelines for health research: a systematic review	35
Acute kidney injury is more common in men than women after accounting for socioeconomic status, ethnicity, alcohol intake and smoking history	34
Sex differences in stroke outcome correspond to rapid and severe changes in gut permeability in adult Sprague-Dawley rats	34
Immune mechanisms associated with sex-based differences in severe COVID-19 clinical outcomes	34
Sex differences in noise-induced hearing loss: a cross-sectional study in China	33
Sex differences associated with adverse drug reactions resulting in hospital admissions	33
Clinical characteristics and outcomes in women and men hospitalized for coronavirus disease 2019 in New Orleans	33
Unveiling sex-based differences in Parkinson's disease: a comprehensive meta-analysis of transcriptomic studies	29
Sex differences in the intestinal microbiome: interactions with risk factors for atherosclerosis and cardiovascular disease	28
Interaction between gut microbiota and sex hormones and their relation to sexual dimorphism in metabolic diseases	27
Sex at the interface: the origin and impact of sex differences in the developing human placenta	27
Sex differences in the medial prefrontal cortical glutamate system	26
A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta	25
Hepatic steatosis and steatohepatitis: a functional meta-analysis of sex-based differences in transcriptomic studies	25
Sex differences in the expression of the endocannabinoid system within V1M cortex and PAG of Sprague Dawley rats	25
The roles of sex and gender in women’s eye health disparities in the United States	24

Female mice exhibit less overall variance, with a higher proportion of structured variance, than males at multiple timescales of continuous body temperature and locomotive activity records	23
Sex differences in the aging murine urinary bladder and influence on the tumor immune microenvironment of a carcinogen-induced model of bladder cancer	22
Sex-dependent differences in the secretome of human endothelial cells	21
Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types	21
Sex differences in the association between cardiovascular diseases and dementia subtypes: a prospective analysis of 464,616 UK Biobank participants	20
Gender differences in the efficacy of pioglitazone treatment in nonalcoholic fatty liver disease patients with abnormal glucose metabolism	19
Consideration of sex and gender differences in addiction medication response	19
Investigating the sex-dependent effects of prefrontal cortex stimulation on response execution and inhibition	18
Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition	17
Association of menopausal status with COVID-19 outcomes: a propensity score matching analysis	17
Impact of sex in the prevalence and progression of glioblastomas: the role of gonadal steroid hormones	17
Gender differences in cardiometabolic health and disease in a cross-sectional observational obesity study	16
Role of GDF-15, YKL-40 and MMP 9 in patients with end-stage kidney disease: focus on sex-specific associations with vascular outcomes and all-cause mortality	16
Considering sex and gender in Epidemiology: a challenge beyond terminology. From conceptual analysis to methodological strategies	16
Sex-dependent variation in cartilage adaptation: from degeneration to regeneration	15
Sex differences in the association of sphingolipids with age in Dutch and South-Asian Surinamese living in Amsterdam, the Netherlands	15
Sex difference in the association between plasma selenium and first stroke: a community-based nested case-control study	15
Gender score development in the Berlin Aging Study II: a retrospective approach	15
Shortening time for access to alcohol drives up front-loading behavior, bringing consumption in male rats to the level of females	15
Sexual dimorphism of monocyte transcriptome in individuals with chronic low-grade inflammation	15
A retrospective study on sex difference in patients with urolithiasis: who is more vulnerable to chronic kidney disease?	14
Differential expression of microRNAs in the hippocampi of male and female rodents after chronic alcohol administration	14
Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice	13
Characterisation of cardiac health in the reduced uterine perfusion pressure model and a 3D cardiac spheroid model, of preeclampsia	13
The diagnostic potential of oxidative stress biomarkers for preeclampsia: systematic review and meta-analysis	13
Age-dependent changes of gender disparities in nasopharyngeal carcinoma survival	13
Ischemic preconditioning protects the heart against ischemia-reperfusion injury in chronic kidney disease in both males and females	13
Sex and age differences in the association of fatty liver index-defined non-alcoholic fatty liver disease with cardiometabolic risk factors: a cross-sectional study	13
Gestational hypoxia in late pregnancy differentially programs subcortical brain maturation in male and female rat offspring	13
Sex differences in sucrose reinforcement in Long-Evans rats	13
Sex-biased and parental allele-specific gene regulation by KDM6A	13
Considerations and challenges for sex-aware drug repurposing	13
TLR8 escapes X chromosome inactivation in human monocytes and CD4+ T cells	13
Selective deletion of endothelial mineralocorticoid receptor protects from vascular dysfunction in sodium-restricted female mice	13
Increased P450 aromatase levels in post-menopausal women after acute ischemic stroke	13
Sex-specific differences in zebrafish brains	13
Predicting respiratory failure in patients infected by SARS-CoV-2 by admission sex-specific biomarkers	12
Advances in sex disparities for cancer immunotherapy: unveiling the dilemma of Yin and Yang	12
Sex-divergent effects on the NAD+-dependent deacetylase sirtuin signaling across the olfactory–entorhinal–amygdaloid axis in Alzheimer’s and Parkinson’s diseases	12
Overall and sex-specific risk factors for subjective cognitive decline: findings from the 2015–2018 Behavioral Risk Factor Surveillance System Survey	12
Angiotensin II type 1 receptor agonistic autoantibody blockade improves postpartum hypertension and cardiac mitochondrial function in rat model of preeclampsia	12
Analysis of sex differences in dietary copper-fructose interaction-induced alterations of gut microbial activity in relation to hepatic steatosis	12
Menopause causes metabolic and cognitive impairments in a chronic cerebral hypoperfusion model of vascular contributions to cognitive impairment and dementia	12
Sex differences in a cohort of COVID-19 Italian patients hospitalized during the first and second pandemic waves	12
Sex differences in renal cell carcinoma: a single-cell analysis reveals exhausted CD8+ T-cells highly infiltrated in males	12
Sex-dependent effects of prenatal food and protein restriction on offspring physiology in rats and mice: systematic review and meta-analyses	12
Bile acid distributions, sex-specificity, and prognosis in colorectal cancer	11
Important differences between hypertensive middle-aged women and men in cardiovascular autonomic control—a critical appraisal	11
A sex difference in mouse dopaminergic projections from the midbrain to basolateral amygdala	11
Investigation of autism-related transcription factors underlying sex differences in the effects of bisphenol A on transcriptome profiles and synaptogenesis in the offspring hippocampus	11

Sex differences in muscle protein expression and DNA methylation in response to exercise training	11
Fetal sex and maternal postpartum depressive symptoms: findings from two prospective pregnancy cohorts	11
Chromosomal and gonadal sex drive sex differences in lipids and hepatic gene expression in response to hypercholesterolemia and statin treatment	10
Integrated analysis of robust sex-biased gene signatures in human brain	10
Postnatal developmental trajectory of sex-biased gene expression in the mouse pituitary gland	10
The associations of hostility and defensiveness with telomere length are influenced by sex and health status	10
Sex differences in soluble prorenin receptor in patients with type 2 diabetes	10
Activation of G protein-coupled estradiol receptor 1 in the dorsolateral striatum enhances motivation for cocaine and drug-induced reinstatement in female but not male rats	10