OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Tissue Engineering is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Therapeutic potential and mechanisms of umbilical cord mesenchymal stem cells differentiating into tendon cells and promotion of rotator cuff tendon-bone healing	103
Additively manufactured bioceramic scaffolds based on triply periodic minimal surfaces for bone regeneration	103
Promoting angiogenesis and diabetic wound healing through delivery of protein transduction domain-BMP2 formulated nanoparticles with hydrogel	91
An organotypic oral mucosal infection model to study host-pathogen interactions	77
Asymmetric biphasic electric stimulation supports cardiac maturation and functionality	74
Advanced 3D bioprinted liver models with human-induced hepatocytes for personalized toxicity screening	69
Decellularization for the retention of tissue niches	64
Construction of a pancreatic cancer nerve invasion system using brain and pancreatic cancer organoids	54
Corrigendum to “Tendon tissue engineering: An overview of biologics to promote tendon healing and repair”	53
Tissue-engineered composite tracheal grafts create mechanically stable and biocompatible airway replacements	48
Advances in tissue engineering of peripheral nerve and tissue innervation – a systematic review	41
Generation of a tendon-like tissue from human iPS cells	38
Soft substrates direct stem cell differentiation into the chondrogenic lineage without the use of growth factors	36
Continuous nutrient supply culture strategy controls multivesicular endosomes pathway and anti-photo-aging miRNA cargo loading of extracellular vesicles	35
Blood mononuclear cells induce accelerated vascular remodeling under acute inflammation in vitro	33
Vascularized characteristics and functional regeneration of three-dimensional cell reconstruction of oral mucosa equivalents based on vascular homeostasis phenotypic modification	33
Differential stress responses of immunoisolated human islets embedded in pancreatic extracellular matrix under static and free-fall dynamic conditions	32
Regeneration of articular cartilage defects: Therapeutic strategies and perspectives	31
In vitro elastic cartilage reconstruction using human auricular perichondrial chondroprogenitor cell–derived micro 3D spheroids	31
Microfluidic organ-on-a-chip for modeling coronary artery disease: Recent applications, limitations and potential	31
Steering the multipotent mesenchymal cells towards an anti-inflammatory and osteogenic bias via photobiomodulation therapy: How to kill two birds with one stone	31
Enhanced effects of antagomiR-3074-3p-conjugated PEI-AuNPs on the odontogenic differentiation by targeting FKBP9	29
Hair regeneration: Mechano-activation and related therapeutic approaches	29
Advanced lung organoids for respiratory system and pulmonary disease modeling	27
Gene editing strategies to address current challenges in stem cell-derived β cell therapy for type 1 Diabetes	27

Gum-on-a-Chip Exploring Host-Microbe Interactions: Periodontal Disease Modeling and Drug Discovery	27
Microvessels derived from hiPSCs are a novel source for angiogenesis and tissue regeneration	27
Spheroid assembly of mesenchymal stem cells enhances secretome-mediated corneal reinnervation and epithelial repair in a mouse model of experimental dry eye	26
Design of an artificial natural killer cell mimicking system to target tumour cells	26
Stage-specific cardiotoxicity induced by bisphenol A using human pluripotent stem cell-derived 2D- and 3D-cardiomyocyte models	25
Emerging strategies for tissue engineering in vascularized composite allotransplantation: A review	25
Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization	25
High-throughput, real-time monitoring of engineered skeletal muscle function using magnetic sensing	24
Immunomodulation in diabetic wounds healing: The intersection of macrophage reprogramming and immunotherapeutic hydrogels	24
Exosomal non-coding RNAs: Emerging insights into therapeutic potential and mechanisms in bone healing	24
Preclinical and clinical orthotopic transplantation of decellularized/engineered tracheal scaffolds: A systematic literature review	24
Development of an iPSC-derived immunocompetent skin model for identification of skin sensitizing substances	23
Nanodrug delivery systems for regulating microglial polarization in ischemic stroke treatment: A review	23
Cell secretomes for wound healing and tissue regeneration: Next generation acellular based tissue engineered products	22
In situ regeneration of nasal septal defects using acellular cartilage enhanced with platelet-derived growth factor	22
A global bibliometric and visualized analysis in the status and trends of corneal tissue engineering research from 1991 to 2021	22
Expanding tubular microvessels on stiff substrates with endothelial cells and pericytes from the same adult tissue	22
Engineering growth factor gradients to drive spatiotemporal tissue patterning in organ-on-a-chip systems	21
Liver scaffolds obtained by decellularization: A transplant perspective in liver bioengineering	21
Tendon tissue engineering: An overview of biologics to promote tendon healing and repair	21
A new cell-free therapeutic strategy for liver regeneration: Human placental mesenchymal stem cell-derived extracellular vesicles	20
Intranasal delivery systems for traumatic brain injury: Advancements and perspectives	20
Controlled spatial and temporal release of neurotrophic growth factor from genetically modified tissue engineering living scaffolds	19
RANKL neutralisation prevents osteoclast activation in a human in vitro ameloblastoma-bone model	19
Non-hypertrophic chondrogenesis of mesenchymal stem cells through mechano-hypoxia programing	19
Advances in hydrogels for capturing and neutralizing inflammatory cytokines	18
SP7 gene silencing dampens bone marrow stromal cell hypertrophy, but it also dampens chondrogenesis	18
Retraction: Estradiol-17β [E2] stimulates wound healing in a 3D in vitro tissue-engineered vaginal wound model	17
Unlocking the regenerative key: Targeting stem cell factors for bone renewal	17
Two-dimensional vascularized liver organoid on extracellular matrix with defined stiffness for modeling fibrotic and normal tissues	16
Bioengineering strategies targeting angiogenesis: Innovative solutions for osteonecrosis of the femoral head	16
Mechanisms of hydrogel-based microRNA delivery systems and its application strategies in targeting inflammatory diseases	16
Peptide nanogels as a scaffold for fabricating dermal grafts and 3D vascularized skin models	16
Extracellular vesicles delivering nuclear factor I/C for hard tissue engineering: Treatment of apical periodontitis and dentin regeneration	16
Mechanically activated mesenchymal-derived bone cells drive vessel formation via an extracellular vesicle mediated mechanism	16