Chemical Science

Article	Citations
Back cover	269
Enantioselective nickel-catalyzed Mizoroki–Heck cyclizations of amide electrophiles	255
Simulation of ultrafast transient absorption spectra of a perylene-based light harvesting antenna	241
Back cover	239
Phototoxicity of hydroxymethyl-BODIPYs: are photocages that innocent?	236
Contents list	223
Inside front cover	193
Inside front cover	187
Gaining control on optical force by the stimulated-emission resonance effect	180
Correction: FragGen: towards 3D geometry reliable fragment-based molecular generation	176
Three-dimensional structural alignment based discovery and molecular basis of AtoB, catalyzing linear tetracyclic formation	170
Back cover	170
Correction: Structural tuning of organoruthenium compounds allows oxidative switch to control ER stress pathways and bypass multidrug resistance	169
Correction: Multi-stimuli programmable FRET based RGB absorbing antennae towards ratiometric temperature, pH and multiple metal ion sensing	166
Correction: Magnetic coupling between Fe(NO) spin probe ligands through diamagnetic NiII, PdII and PtII tetrathiolate bridges	164
Front cover	162
Front cover	162
Contents list	151
Contents list	150
Light-controlled enzymatic synthesis of γ-CD using a recyclable azobenzene template	150
Inside front cover	146
Back cover	146
Inside back cover	146
Front cover	144
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Inside front cover	141
Contents list	136
Inside back cover	132
Photochemical synthesis of carbazole-fused Blatter radicals: effective spin injection to the carbazole system	130
Back cover	130
Syntheses, homeomorphic and configurational isomerizations, and structures of macrocyclic aliphatic dibridgehead diphosphines; molecules that turn themselves inside out	126
Back cover	126
Study of the thermally-activated delayed fluorescence (TADF) mechanism of phenothiazine–dibenzothiophene- S , S	125
DNP NMR spectroscopy enabled direct characterization of polystyrene-supported catalyst species for synthesis of glycidyl esters by transesterification	125
Effect of cyclic topology versus linear terpolymers on antibacterial activity and biocompatibility: antimicrobial peptide avatars	122
Photo-generated radical mediated molecular luminescence enhancement	122
A tetraazanaphthalene radical-bridged dysprosium single-molecule magnet with a large coercive field	120
Detection of single-cell enzyme activity by single-time-point stable isotope probing-mass spectrometry	120
Development of 8–17 XNAzymes that are functional in cells	120
Front cover	119
18F-Labeled brain-penetrant EGFR tyrosine kinase inhibitors for PET imaging of glioblastoma	118
Site-specific doping of silver atoms into a Au25 nanocluster as directed by ligand binding preferences	116
An AND-gate bioluminescent probe for precise tumor imaging	116
Unveiling upsurge of photogenerated ROS: control of intersystem crossing through tuning aggregation patterns	113
Revealing the nature of covalently tethered distonic radical anions in the generation of heteroatom-centered radicals: evidence for the polarity-matching PCET pathway	112
Front cover	107
Correction: When SF5 outplays CF3: effects of pentafluorosulfanyl decorated scorpionates on copper	107
Visible-light-initiated metal-free Csp3–Csp3 to Csp3–N conversion in homobenzylic sulfonamides with N-iodoimides	107
Time-resolved circular dichroism of excitonic systems: theory and experiment on an exemplary squaraine polymer	107
Peptide stereocomplex cross-links for polymer hydrogels	106
Negative cooperativity in the formation of H-bond networks involving primary anilines	105
Impact of vibrational strong coupling on liquid–liquid phase separation in supramolecular polymers	104
Engineering mechanisms of proton-coupled electron transfer to a titanium-substituted polyoxovanadate–alkoxide	103
Synthesis of functionalised isochromans: epoxides as aldehyde surrogates in hexafluoroisopropanol	103
Mechanism of action and evaluation of ratiometric probes for uric acid using lanthanide complexes with tetraazatriphenylene sensitisers	102
High order assembly of multiple protein cages with homogeneous sizes and shapes via limited cage surface engineering	102
Aminocatalytic enantioselective [2 + 2] cycloaddition of Bicyclo[1.1.0]butanes and α,β-unsaturated aldehydes	101
Multi-region mapping of ligand binding and structural changes in the β-1 adrenergic receptor using carbene footprinting and mass spectrometry	101
Biosynthesis of pleuromutilin congeners using an Aspergillus oryzae expression platform	100
Facile modification of phosphole-based aggregation-induced emission luminogens with sulfonyl isocyanates	99
Photochemical H2 activation by an Zn–Fe heterometallic: a mechanistic investigation	98
Correction: Site- and stereoselective silver-catalyzed intramolecular amination of electron-deficient heterobenzylic C–H bonds	97
Inside front cover	96
Metalation-induced denitrogenative reductive coupling of isocyanides on a silylene-bridged nickel cluster	96
Front cover	95
Identification of allosteric sites and ligand-induced modulation in the dopamine receptor through large-scale alchemical mutation scan	94
Inside front cover	94
Defect-engineered surfaces to investigate the formation of self-assembled molecular networks	93
Excitation generated preferential binding sites for ethane on porous carbon–copper porphyrin sorbents: ethane/ethylene adsorptive separation improved by light	93
Light-induced twisting, untwisting, and retwisting of aromatic polyamides: an interplay between the induced chirality and the co-facial π-stacking interactions	93
Electrochemical hydrogenative coupling of nitrobenzene into azobenzene over a mesoporous palladium–sulfur cathode	92
Transcriptome-wide identification of single-stranded RNA binding proteins	91
Luminescent carbene–copper(i)–amide polymers for efficient host-free solution-processed OLEDs	91
Controlled, one-pot synthesis of recyclable poly(1,3-diene)-polyester block copolymers, catalyzed by yttrium β-diketiminate complexes	90
Direct detection of spin polarization in photoinduced charge transfer through a chiral bridge	90

109Ag NMR chemical shift as a descriptor for Brønsted acidity from molecules to materials	90
Retaining the structural integrity of disulfide bonds in diphtheria toxoid carrier protein is crucial for the effectiveness of glycoconjugate vaccine candidates	89
Redox-neutral manganese-catalyzed synthesis of 1-pyrrolines	89
Correction: Ultrahigh photocatalytic hydrogen evolution of linear conjugated terpolymers enabled by an ultra-low ratio of the benzothiadiazole monomer	89
Discovery strategy leads to the first melt-castable cocrystal based on an energetic oxidizing salt	88
Coexisting gases regulate the rates of water adsorption by a flexible one-dimensional coordination polymer	87
Visible light-driven dearomative ring expansion of (aza)arenes to access dihydrofuran-based polycyclic compounds	87
Isothiourea-catalysed enantioselective synthesis of phosphonate-functionalised β-lactones	87
Affinity-based protein profiling of MDM2 inhibitor Navtemadlin	87
The organophosphorus synthesis triangle: introducing methods for the missing quaternization and de-quaternization routes	87
Chiral cobalt( ii ) complex-promoted asymmetric para -Claisen rearrangement of allyl α-naphthol ethers	86
Structure–function relationships in pure archaeal bipolar tetraether lipids	86
Ultrafast and selective labeling of endogenous proteins using affinity-based benzotriazole chemistry	86
Proton transfer induced excited-state aromaticity gain for chromophores with maximal Stokes shifts	85
Mechanism and dynamics of photoswitchable flavoprotein charge-transfer complexes	85
Probing substrate binding inside a paramagnetic cavity: a NMR spectroscopy toolbox for combined experimental and theoretical investigation	84
More π, please: What drives the formation of unsaturated molecules in the interstellar medium?	84
Guiding catalytic CO 2 reduction to ethanol with copper grain boundaries	83
Therapeutic efficacy of 211 At-radiolabeled 2,6-diisopropylphenyl azide in mouse models of human lung cancer	83
Molybdenum carbonyl assisted reductive tetramerization of CO by activated magnesium( i ) compounds: squarate dianion vs.	83
Deciphering the chemical bonding of the trivalent oxygen atom in oxygen doped graphene	82
Enhanced N-directed electrophilic C–H borylation generates BN–[5]- and [6]helicenes with improved photophysical properties	81
A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters	81
Mechanisms of controlled stabilizer-free synthesis of gold nanoparticles in liquid aerosol containing plasma	80
Characterization of a LanC-free pathway for the formation of an ll -MeLan residue and an allo AviMeCys	80
A pair of conjoined trinuclear sub-frameworks in a pentanuclear double-cavity discrete coordination cage	79
Leveraging heterocycle-fused 1,4-benzoquinone to design chemical modulators for both metal-free and metal-bound amyloid-β	79
Easy access to amphiphilic nitrogenous block copolymers via switchable catalysis	79
A silylboronate-mediated strategy for cross-coupling of alkyl fluorides with aryl alkanes: mechanistic insights and scope expansion	78
Intramolecular CH⋯π attraction mediated conformational polymorphism of constrained helical peptides	78
Probing the water adsorption and stability under steam flow of Zr-based metal–organic frameworks using 91Zr solid-state NMR spectroscopy	77
The supersaturation perspective on the amyloid hypothesis	77
(3 + 2)-Cycloaddition of bicyclobutanes and thioketones: access to 2-thiabicyclo[2.1.1]hexanes without the use of catalysts or light	77
Inter-layer magnetic tuning by gas adsorption in π-stacked pillared-layer framework magnets	77
Efficient helical columnar emitters of chiral homoleptic Pt(ii) metallomesogens for circularly polarized electroluminescence	77
Room temperature dinitrogen cleavage and hydrogenation with organometallic complexes of uranium	76
Double coordination shell modulation of nitrogen-free atomic manganese sites for enhancing oxygen reduction performance	76
First synthesis of RuSn solid-solution alloy nanoparticles and their enhanced hydrogen evolution reaction activity	76
Catalytic asymmetric hydrometallation of cyclobutenes with salicylaldehydes	75
Dynamic handedness inversion of self-organized helical superstructures enabled by novel thermally stable light-driven chiral hydrazone switches	75
Arresting dissolution of two-dimensional metal–organic frameworks enables long life in electrochemical devices	75
With or without a co-solvent? highly efficient ultrafast phenanthrenequinone-electron rich alkene (PQ-ERA) photoclick reactions	75
Reactivity of 1,3-enyne MIDA boronates: exploration of novel 1,2-alkyne shift via gem-difluorination	75
Bromine radical release from a nickel-complex facilitates the activation of alkyl boronic acids: a boron selective Suzuki–Miyaura cross coupling	75
Isostructural bridging diferrous chalcogenide cores [FeII(μ-E)FeII] (E = O, S, Se, Te) with decreasing antiferromagnetic coupling down the chalcogenide series	75
Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the α/β-hydrolase fold	75
Rational design of circularly polarized luminescence active chiral metal–organic frameworks for logic devices	75
Accelerating the end-to-end production of cyclic phosphate monomers with modular flow chemistry	74
Nature of the heavy formal double bonds AsCh, SbCh and BiCh (Ch = S, Se, Te) in NCN-pincer supported arsinidene, stibinidene and bismuthinidene chalcogenides	74
Tuning through-space interactions via the secondary coordination sphere of an artificial metalloenzyme leads to enhanced Rh(iii)-catalysis	74
De novogeneration of a bright blue fluorophore from 2-oxoglutarate in biological samples	74
A methyltransferase molecular switch unlocks para -quinone methide generation and oligomerization	73
Photolysis-driven bond activation by thorium and uranium tetraosmate polyhydride complexes	73
Roles of adhesives in forming mechanically robust superhydrophobic coatings	73
Peripherally fused spiro structures enable the development of narrowband TADF emitters for highly efficient blue OLEDs	73
Hydroalkylation of styrenes enabled by boryl radical mediated halogen atom transfer	73
Enhanced ion intercalation in Ni x K 1−2	73
Drop-cast gold nanoparticles are not always electrocatalytically active for the borohydride oxidation reaction	73
Multifaceted nucleic acid probing with a rationally upgraded molecular rotor	72
A reversible plasmonic nanoprobe for dynamic imaging of intracellular pH during endocytosis	72
Intramolecular-locking modification enables efficient asymmetric donor–acceptor–donor′ type ultraviolet emitters for high-performance OLEDs with reduced efficiency roll-off and high color purity	72
MR-TADF liquid crystals: towards self assembling host–guest mixtures showing narrowband emission from the mesophase	72
Deconvoluting binding sites in amyloid nanofibrils using time-resolved spectroscopy	71
Revisiting the reaction pathways for phospholipid hydrolysis catalyzed by phospholipase A2 with QM/MM methods	71
Applications of metal–organic framework-based bioelectrodes	70
Unraveling the local coordination effect of Cu–N–C single-atom catalysts towards CO adsorption via a gas-phase cluster model approach	70
Non-covalent reconfigurable microgel colloidosomes with a well-defined bilayer shell	70
Spectroscopic application of few-femtosecond deep-ultraviolet laser pulses from resonant dispersive wave emission in a hollow capillary fibre	70
Augmenting genetic algorithms with machine learning for inverse molecular design	69
Isoacridone dyes with parallel reactivity from both singlet and triplet excited states for biphotonic catalysis and upconversion	69
In situ modification of the d-band in the core–shell structure for efficient hydrogen storage via electrocatalytic N2 fixation	69
Leveraging reactivity to gain precise control over macromolecular structures with photocatalysis in reversible-deactivation radical polymerizations	69
pH jump kinetics in colliding microdroplets: accelerated synthesis of azamonardine from dopamine and resorcinol	68
Exploring Au(i) involving halogen bonding with N-heterocyclic carbene Au(i) aryl complexes in crystalline media	68
Intramolecular photochemical [2 + 1]-cycloadditions of nucleophilic siloxy carbenes	67
Molecularly engineered AIEgens with enhanced quantum and singlet-oxygen yield for mitochondria-targeted imaging and photodynamic therapy	67
[2 + 2] cycloaddition and its photomechanical effects on 1D coordination polymers with reversible amide bonds and coordination site regulation	67
Molecular brush-based ultrathin polymer electrolytes with stable interfaces for high-voltage large-areal-capacity lithium metal batteries	67
Polymerization-induced self-assembly enables access to diverse highly ordered structures through kinetic and thermodynamic pathways	67
Beyond chemical structures: lessons and guiding principles for the next generation of molecular databases	67

Reducing the internal reorganization energy via symmetry controlled π-electron delocalization	67
Polarization-induced nanohelixes of organic cocrystals from asymmetric components with dopant-induced chirality inversion	67
Competing dynamics of intramolecular deactivation and bimolecular charge transfer processes in luminescent Fe(iii) N-heterocyclic carbene complexes	66
Engineering the solid electrolyte interphase for enhancing high-rate cycling and temperature adaptability of lithium-ion batteries	66
Acridine photocatalysis enables tricomponent direct decarboxylative amine construction	66
Curved graphene nanoribbons derived from tetrahydropyrene-based polyphenylenesviaone-pot K-region oxidation and Scholl cyclization	66
Synthesis of polysubstituted cyclobutanes through a photoredox strain-release/[3,3]-rearrangement cascade	66
MnO2 nanosheets as a carrier and accelerator for improved live-cell biosensing application of CRISPR/Cas12a	66
A method to identify small molecule/protein pairs susceptible to protein ubiquitination by the CRBN E3 ligase	66
Formal synthesis of kibdelomycin and derivatisation of amycolose glycosides	66
A J-aggregated nanoporphyrin overcoming phototoxic side effects in superior phototherapy with two-pronged effects	65
Engineering Pd-based charge-asymmetrical metal pair sites to promote *CHO–CHO coupling for selective C 2 photoreduction to C	65
Orbital electron delocalization of axial-coordinated modified FeN4 and structurally ordered PtFe intermetallic synergistically for efficient oxygen reduction reaction catalysis	65
Intramolecular Transamidation Enables One-Pot Synthesis of Three Chiral, Z-Shaped Perilenediimides for Null-Type Supramolecular Polymer Formation	65
RGB tri-luminescence in organic–inorganic zirconium halide perovskites	65
Synergistic Effect of MOF Fillers and Succinonitrile in PEO-Based Electrolytes for Long-Cycle All-Solid-State Li-CO 2 Battery	64
Sequence-dependent conformational transitions of disordered proteins during condensation	64
Structural insights into a bacterial terpene cyclase fused with haloacid Dehalogenase-like phosphatase	64
A photoinduced transient activating strategy for late-stage chemoselective C(sp3)–H trifluoromethylation of azines	64
In silico screening of LRRK2 WDR domain inhibitors using deep docking and free energy simulations	64
On the use of real-world datasets for reaction yield prediction	64
Ni-catalyzed asymmetric hydrophosphinylation of conjugated enynes and mechanistic studies	63
Biocatalytic reductive amination as a route to isotopically labelled amino acids suitable for analysis of large proteins by NMR	63
Catalysis of a LiF-rich SEI by aromatic structure modified porous polyamine for stable all-solid-state lithium metal batteries	63
Free-energy decomposition of salt effects on the solubilities of small molecules and the role of excluded-volume effects	63
Substituent effects on paratropicity and diatropicity in π-extended hexapyrrolohexaazacoronene	63
LnDOTA puppeteering: removing the water molecule and imposing tetragonal symmetry	63
Visible-light-induced organocatalytic enantioselective N–H insertion of α-diazoesters enabled by indirect free carbene capture	62
“Mn-locking” effect by anionic coordination manipulation stabilizing Mn-rich phosphate cathodes	62
A constitutional isomer selective chemical proteomic strategy for system-wide profiling of protein lysine 5-hydroxylation	62
How do donor and acceptor substituents change the photophysical and photochemical behavior of dithienylethenes? The search for a water-soluble visible-light photoswitch	62
Origin of low melting point of ionic liquids: dominant role of entropy	61
Beyond diffusion: ion and electron migration contribute to charge transport in redox-conducting metal–organic frameworks	61
Ultra-long cycle sodium ion batteries enabled by the glutaric anhydride additive	61
Understanding nascent plasmons and metallic bonding in atomically precise gold nanoclusters	61
Spin polarized electron dynamics enhance water splitting efficiency by yttrium iron garnet photoanodes: a new platform for spin selective photocatalysis	60
A free boratriptycene-type Lewis superacid	60
Modulatory spin-flip of triplet excitons via diversiform electron-donating units for MR-TADF emitters towards solution-processed narrowband OLEDs	60
Deciphering the mechanism of hydrogen peroxide formation in ultrasound-mediated water-in-oil microdroplets	60
Chemiluminescent duplex analysis using phenoxy-1,2-dioxetane luminophores with color modulation	60
Mechanochemically-induced glass formation from two-dimensional hybrid organic–inorganic perovskites	60
A biocompatible hydrogel as a template for oxidative decomposition reactions: a chemodosimetric analysis and in vitro imaging of hypochlorite	60
State-of-the-art accounts of hyperpolarized 15N-labeled molecular imaging probes for magnetic resonance spectroscopy and imaging	59
Molecular cyclo-P3 complexes of the rare-earth elements via a one-pot reaction and selective reduction	59
RAFT step-growth polymerization via the Z-group approach and deconstruction by RAFT interchange	59
Thinking Outside the Library: Cluster Synthesis of Diverse Molecules on a Single Robotic Platform	59
Self-sensitized Cu(ii)-complex catalyzed solar driven CO2 reduction	59
“Dual lock-and-key” triggered and endoplasmic reticulum targeting nanophotosensitizers for activatable Type-I photodynamic and photothermal therapies	59
Ambipolar conjugated ladder polymers by room-temperature Knoevenagel polymerization	59
Two-sided asymmetric nanofluidic membrane for enhanced ion transport and osmotic energy harvesting	59
Bucking the trend: understanding lipopolysaccharide structure and outer membrane dynamics in cold-adapted Pseudomonas isolated from Enigma Lake, Antarctica	58
Facile preparation of sulfonium peptide and protein probes for selective crosslinking of methyllysine readers	58
Simultaneously enhancing the planarity and electron-donating capability of donors for through-space charge transfer TADF towards deep-red emission	58
Identification of metal-centered excited states in Cr(iii) complexes with time-resolved L-edge X-ray spectroscopy	58
Cold-catalytic antitumor immunity with pyroelectric black phosphorus nanosheets	58
Molecular engineering of 1D conjugated copper anilate coordination polymers for boosting electrocatalytic nitrate reduction to ammonia	58
Unified ionic and radical C-4 alkylation and arylation of pyridines	57
Mori generalized master equations offer an efficient route to predict and interpret polaron transport	57
De novo synthesis of inherently chiral heteracalix[4]aromatics from enantioselective macrocyclization enabled by chiral phosphoric acid-catalyzed intramolecular SNAr reaction	57
Influence of the Pt/ionomer/water interface on the oxygen reduction reaction: insights into the micro-three-phase interface	57
Planar pentacoordinate s-block metals	57
Strategic design of Fe and N co-doped hierarchically porous carbon as superior ORR catalyst: from the perspective of nanoarchitectonics	57
Boraindenes as versatile precursors to benzannulated boron heterocycles	57
Highly efficient organic long persistent luminescence based on host–guest doping systems	57
Strain-enabled radical spirocyclization cascades: rapid access to spirocyclobutyl lactones and – lactams	57
Front cover	56
Contents list	56
Correction: Ion pair extractant selective for LiCl and LiBr	56
Lattice-coherent interface-reinforced sodium-layered oxide cathodes	56
Inside front cover	56
Inside front cover	56
Front cover	55
A focus on computer vision for non-contact monitoring of catalyst degradation and product formation kinetics	55
Experiment-guided molecular simulations define a heterogeneous structural ensemble for the PTPN11 tandem SH2 domains	55
Decoupled tin–silver batteries with long cycle life and power output stability based on dendrite-free tin anode and halide insertion cathode chemistry	55
Correction: Cationic pillar[6]arene/ATP host–guest recognition: selectivity, inhibition of ATP hydrolysis, and application in multidrug resistance treatment	55
Correlation-driven charge migration triggered by infrared multi-photon ionization	55
Visible light-induced Mallory reaction of tertiary benzanilides via iminium intermediates	55
Decoding the role of mycobacterial lipid remodelling and membrane dynamics in antibiotic tolerance	55
Unraveling disorder-to-order transitions and chemical ordering in PtCoM ternary alloys using machine learning potential	54
Correction: A comprehensive approach for elucidating the interplay between 4fn+1 and 4fn5d1 configurations in Ln2+ complexes	54
Engineering perfluoroarenes for enhanced molecular barrier effect and chirality transfer in solutions	54
Deducing the conformational space for an octa-proline helix	54
A carbon-based bifunctional heterogeneous enzyme: toward sustainable pollution control	54
Hydrogen atom abstraction as a synthetic route to a square planar CoII complex with a redox-active tetradentate PNNP ligand	54
Front cover	54
Methyl scanning approach for enhancing the biological activity of the linear peptidic natural product, efrapeptin C	54
Dichlorine–pyridine N-oxide halogen-bonded complexes	54
Self-assembled PROTACs enable glycoproteins degradation in the living cells	54
Long-range hydrogen-bond relay catalyses the excited-state proton transfer reaction	54
Contents list	53
Inside back cover	53
Inside front cover	53
Front cover	53
Back cover	53