Chemical Science

Article	Citations
Tunable fluorescent probes for detecting aldehydes in living systems	178
Employing racemization strategies to simultaneously enhance the quantum yield, lifetime, and water stability of room-temperature phosphorescent materials	157
Introducing AFS ([Al(SO3F)3]x) – a thermally stable, readily available, and catalytically active solid Lewis superacid	151
Improving electron transportation and operational lifetime of full color organic light emitting diodes through a “weak hydrogen bonding cage” structure	132
Inside front cover	130
A photoinduced transient activating strategy for late-stage chemoselective C(sp3)–H trifluoromethylation of azines	126
Synthesis, aromatization and cavitates of an oxanorbornene-fused dibenzo[de,qr]tetracene nanobox	122
Defect-engineered surfaces to investigate the formation of self-assembled molecular networks	114
Construction of an autocatalytic reaction cycle in neutral medium for synthesis of life-sustaining sugars	113
An integrated “rigid–flexible” strategy by side chain engineering towards high ion-conduction cationic covalent organic framework electrolytes	112
The unprecedented strong paratropic ring current of a bis-PdII complex of 5,10,23-trimesityl [28]heptaphyrin(1.1.0.0.1.0.0)	111
A pair of conjoined trinuclear sub-frameworks in a pentanuclear double-cavity discrete coordination cage	109
A multi-resonance emitter with five-membered thiophene as the π-core enables efficient, narrowband and reduced efficiency roll-off OLEDs	107
Luminescent carbene–copper(i)–amide polymers for efficient host-free solution-processed OLEDs	107
Structure-enabled long-lived charge separation in single crystals of an asymmetric donor–acceptor perylenediimide cyclophane	105
Synthesis of a dendritic cell-targeted self-assembled polymeric nanoparticle for selective delivery of mRNA vaccines to elicit enhanced immune responses	103
Inexpensive and bench stable diarylmethylium tetrafluoroborates as organocatalysts in the light mediated hydrosulfonylation of unactivated alkenes	102
A critical appraisal of advances in integrated CO2 capture and electrochemical conversion	100
Engineering mechanisms of proton-coupled electron transfer to a titanium-substituted polyoxovanadate–alkoxide	98
Self-sensitized Cu(ii)-complex catalyzed solar driven CO2 reduction	98
Exploring new horizons in mid-to-far infrared nonlinear optical crystals: the significant potential of trigonal pyramidal [TeS3]2− functional units	97
Engineering the solid electrolyte interphase for enhancing high-rate cycling and temperature adaptability of lithium-ion batteries	93
Mechanistic insights into the regiodivergent insertion of bicyclo[1.1.0]butanes towards carbocycle-tethered N-heteroarenes	90
Enhancing electrocatalytic hydrogen evolution via engineering unsaturated electronic structures in MoS2	90
Surface immobilization of single atoms on heteroatom-doped carbon nanospheres through phenolic-mediated interfacial anchoring for highly efficient biocatalysis	87

Precise photorelease in living cells by high-viscosity activatable coumarin-based photocages	85
Interplay between conformational dynamics and substrate binding regulates enzymatic activity: a single-molecule FRET study	84
Enhancing organic cathodes of aqueous zinc-ion batteries via nitro group modification	83
Discovery of Intermolecular Cascade Annulation for Dihydrobenzo[b][1,8]naphthyridine-Ylidene-Pyrrolidinetriones	80
On the breakdown of Förster energy transfer theory due to solvent effects: atomistic simulations unveil distance-dependent dielectric screening in calmodulin	78
Late-stage installation and functionalization of alkyl pyridiniums: a general HTE amenable strategy to access diverse aryl alanine containing macrocyclic peptides	78
Enzymatic Peptide Macrocyclization via Indole-N-Acylation	78
The inductive effect does not explain electron density in haloacetates: are our textbooks wrong?	78
Li1.6AlCl3.4S0.6: a low-cost and high-performance solid electrolyte for solid-state batteries	77
Catalysis of a LiF-rich SEI by aromatic structure modified porous polyamine for stable all-solid-state lithium metal batteries	76
Spatial correlation of desorption events accelerates water exchange dynamics at Pt/water interfaces	74
Anatomy and formation mechanisms of early amyloid-β oligomers with lateral branching: graph network analysis on large-scale simulations	73
Photocatalytic synthesis of tetra-substituted furans promoted by carbon dioxide	73
Discovery of a monomeric green fluorescent protein sensor for chloride by structure-guided bioinformatics	73
Lessons learnt in photocatalysis – the influence of solvent polarity and the photostability of the photocatalyst	72
Hydroalkylation of styrenes enabled by boryl radical mediated halogen atom transfer	72
Bicyclic (alkyl)(amino)carbene (BICAAC) in a dual role: activation of primary amides and CO2towards catalyticN-methylation	71
Free-energy decomposition of salt effects on the solubilities of small molecules and the role of excluded-volume effects	69
Dynamic structural evolution of MgO-supported palladium catalysts: from metal to metal oxide nanoparticles to surface then subsurface atomically dispersed cations	68
Fine-regulation of gradient gate-opening in nanoporous crystals for sieving separation of ternary C3 hydrocarbons	68
Singlet fission in TIPS-anthracene thin films	68
Chemo-selective Stille-type coupling of acyl-chlorides upon phosphine-borane Au(i) catalysis	67
Hypocretenolides: collective total syntheses and activities toward metastatic colon cancer	67
Photocatalytic CO2reduction sensitized by a special-pair mimic porphyrin connected with a rhenium(i) tricarbonyl complex	66
Highly elastic relaxor ferroelectric via peroxide crosslinking	66
Back cover	65
Inside front cover	65
δ-Bonding modulates the electronic structure of formally divalent nd1 rare earth arene complexes	64
Catalytic enantioselective synthesis of 2-pyrazolines via one-pot condensation/6π-electrocyclization: 3,5-bis(pentafluorosulfanyl)-phenylthioureas as powerful hydrogen bond donors	64
Inside back cover	64
Exfoliation of a metal–organic framework enabled by post-synthetic cleavage of a dipyridyl dianthracene ligand	64
Four-electron reduction of CO2: from formaldehyde and acetal synthesis to complex transformations	63
Efficient circularly polarized multiple resonance thermally activated delayed fluorescence from B,N-embedded hetero[8]helicene enantiomers	63
Targeting lysosomes by design: novel N-acridine thiosemicarbazones that enable direct detection of intracellular drug localization and overcome P-glycoprotein (Pgp)-mediated resistance	63
Anion transporters based on halogen, chalcogen, and pnictogen bonds: towards biological applications	63
Excitonic cuprophilic interactions in one-dimensional hybrid organic–inorganic crystals	62
Molecular modulation strategies for two-dimensional transition metal dichalcogenide-based high-performance electrodes for metal-ion batteries	62
Surefire generation of stannylpotassium: highly reactive stannyl anions and applications	62
Hydrophobic nanoporous carbon scaffolds reveal the origin of polarity-dependent electrocapillary imbibition	60
SDEGen: learning to evolve molecular conformations from thermodynamic noise for conformation generation	60
Back cover	60
In situ modification of the d-band in the core–shell structure for efficient hydrogen storage via electrocatalytic N2 fixation	60
Diastereoselective hydride transfer enables a synthesis of chiral 1,5-carboxamido-trifluoromethylcarbinols	60
Equilibrating parent aminomercaptocarbene and CO2 with 2-amino-2-thioxoacetic acid via heavy-atom quantum tunneling	60
Inter-layer magnetic tuning by gas adsorption in π-stacked pillared-layer framework magnets	60
Artificial design of organic emitters via a genetic algorithm enhanced by a deep neural network	59
A biocompatible hydrogel as a template for oxidative decomposition reactions: a chemodosimetric analysis and in vitro imaging of hypochlorite	59
Hydroxy-directed fluorination of remote unactivated C(sp3)–H bonds: a new age of diastereoselective radical fluorination	59
Accelerating the end-to-end production of cyclic phosphate monomers with modular flow chemistry	59
CCC pincer Ru complex-catalyzed C–H vinylation/6π-E-cyclization of aldimines for constructing 4H-pyrido[1,2-a]pyrimidines	58

Contents list	58
The ACE2 receptor accelerates but is not biochemically required for SARS-CoV-2 membrane fusion	57
Heavy metalla vinyl-cations show metal–Lewis acid cooperativity in reaction with small molecules (NH3, N2H4, H2O, H2)	57
A bis(silylene)pyridine pincer ligand can stabilize mononuclear manganese(0) complexes: facile access to isolable analogues of the elusive d7-Mn(CO)5radical	56
Light-driven redox deracemization of indolines and tetrahydroquinolines using a photocatalyst coupled with chiral phosphoric acid	56
Imprinting of nanoparticles in thin films: Quo Vadis?	55
A system for artificial light signal transduction via molecular translocation in a lipid membrane	54
Asymmetric imino-acylation of alkenes enabled by HAT-photo/nickel cocatalysis	54
Arresting dissolution of two-dimensional metal–organic frameworks enables long life in electrochemical devices	52
Back cover	52
Unlocking the chemical environment of nitrogen in perovskite-type oxides	51
Strain-enabled radical spirocyclization cascades: rapid access to spirocyclobutyl lactones and – lactams	51
Subphthalocyanine capsules: molecular reactors for photoredox transformations of fullerenes	51
Electronic configuration regulation of single-atomic Mn sites mediated by Mo/Mn clusters for an efficient hydrogen evolution reaction	51
Ni-catalyzed asymmetric hydrophosphinylation of conjugated enynes and mechanistic studies	50
Inside front cover	50
Catalytic, asymmetric carbon–nitrogen bond formation using metal nitrenoids: from metal–ligand complexes via metalloporphyrins to enzymes	50
Chemical and linguistic considerations for encoding Chinese characters: an embodiment using chain-end degradable sequence-defined oligourethanes created by consecutive solid phase click chemistry	50
Engendering reactivity at group 5-heteroatom multiple bondsviaπ-loading	50
Contents list	49
Inside back cover	49
Inside front cover	48
Front cover	48
Inside back cover	48
Contents list	48
Metalation-induced denitrogenative reductive coupling of isocyanides on a silylene-bridged nickel cluster	47
Front cover	47
Inside back cover	47
Inside front cover	46
Back cover	46
Inside back cover	46
Back cover	46
Contents list	45
Front cover	45
Contents list	45
Angle-dependent strength of a single chemical bond by stereographic force spectroscopy	45
Oxidatively induced reactivity in Rh(iii)-catalyzed 7-azaindole synthesis: insights into the role of the silver additive	45
Contents list	44
Front cover	44
Highly effective and chemoselective hydrodeoxygenation of aromatic alcohols	44
De novogeneration of a bright blue fluorophore from 2-oxoglutarate in biological samples	44
Inside front cover	44
Contents list	44
Back cover	43
Back cover	43
Stereoselective synthesis of [2.2]triphenylenophanesviaintramolecular double [2 + 2 + 2] cycloadditions	43
Contents list	43
Direct observation of magnetoelastic coupling in a molecular spin qubit: new insights from crystal field neutron scattering data	43
Contents list	43
Front cover	43
Mechanical codes of chemical-scale specificity in DNA motifs	42
Recognition competes with hydration in anion-triggered monolayer formation of cyanostar supra-amphiphiles at aqueous interfaces	42
Back cover	42
Gaining control on optical force by the stimulated-emission resonance effect	42
Stille type P–C coupling polycondensation towards phosphorus-crosslinked polythiophenes with P-regulated photocatalytic hydrogen evolution	42
Front cover	42
Rate and equilibrium constants for the addition of triazolium salt derived N-heterocyclic carbenes to heteroaromatic aldehydes	42
Migratory insertion of isocyanide into a ketenyl–tungsten bond as key step in cyclization reactions	41
A different polynorbornene backbone by combination of two polymer growth pathways: vinylic addition and ring opening via β-C elimination	41
Streamlining the interface between electronics and neural systems for bidirectional electrochemical communication	41
Robust vibrational coherence protected by a core–shell structure in silver nanoclusters	40
Probing protein aggregation at buried interfaces: distinguishing between adsorbed protein monomers, dimers, and a monomer–dimer mixture in situ	40
Design enhancement in hydroxide ion conductivity of viologen–bakelite organic frameworks for a flexible rechargeable zinc–air battery	40
Divergent stereochemical outcomes in the insertion of donor/donor carbenes into the C–H bonds of stereogenic centers	40
Iridium-catalyzed asymmetric trans-selective hydrogenation of 1,3-disubstituted isoquinolines	40
Ultrafast photogeneration of a metal–organic nitrene from 1,1′-diazidoferrocene	40
General stereoretentive preparation of chiral secondary mixed alkylmagnesium reagents and their use for enantioselective electrophilic aminations	40
Interrogating bioinspired ESIPT/PCET-based Ir(iii)-complexes as organelle-targeted phototherapeutics: a redox-catalysis under hypoxia to evoke synergistic ferroptosis/apoptosis	40
Direct discrimination of cell surface glycosylation signatures using a single pH-responsive boronic acid-functionalized polymer	40
Responsive calcium-derived nanoassemblies induce mitochondrial disorder to promote tumor calcification	39
A conformational role for NifW in the maturation of molybdenum nitrogenase P-cluster	39
Magnetically controlled assembly: a new approach to organic integrated photonics	39
Stereoselective RNA reaction with chiral 2′-OH acylating agents	39
Autofluorescent antimalarials by hybridization of artemisinin and coumarin: in vitro/in vivo studies and live-cell imaging	39
Synthesis of functionalised isochromans: epoxides as aldehyde surrogates in hexafluoroisopropanol	39
Backbone-controlled LUMO energy induces intramolecular C–H activation inortho-bis-9-borafluorene-substituted phenyl ando-carboranyl compounds leading to novel 9,10-diboraanthracene deriv	39
Interface engineering of Li6.75La3Zr1.75Ta0.25O12via in situ built LiI/ZnLix mixed buffer layer for solid-state lithium	39
3D vs. turbostratic: controlling metal–organic framework dimensionality via N-heterocyclic carbene chemistry	39
Substituent effects on aromatic interactions in water	38
Photocatalytic NOx removal and recovery: progress, challenges and future perspectives	38

A photo-switchable molecular capsule: sequential photoinduced processes	38
Three-component reductive conjugate addition/aldol tandem reaction enabled by nickel/photoredox dual catalysis	38
Understanding chemistry: from “heuristic (soft) explanations and reasoning by analogy” to “quantum chemistry”	38
Single-nucleobase resolution of a surface energy transfer nanoruler for in situ measurement of aptamer binding at the receptor subunit level in living cells	38
Tuning the photoactivated anticancer activity of Pt(iv) compounds via distant ferrocene conjugation	37
Competing dynamics of intramolecular deactivation and bimolecular charge transfer processes in luminescent Fe(iii) N-heterocyclic carbene complexes	37
Redox-neutral manganese-catalyzed synthesis of 1-pyrrolines	37
Chemical sensors for imaging total cellular aliphatic aldehydes in live cells	37
Palladium-catalyzed selective C–C bond cleavage of keto-vinylidenecyclopropanes: construction of structurally rich dihydrofurans and tetrahydrofurans	36
Endogenous metal-ion dynamic nuclear polarization for NMR signal enhancement in metal organic frameworks	36
Predicting valence tautomerism in diverse cobalt–dioxolene complexes: elucidation of the role of ligands and solvent	36
Enantioconvergent synthesis of chiral fluorenols from racemic secondary alcohols via Pd(ii)/chiral norbornene cooperative catalysis	36
Spectroscopic application of few-femtosecond deep-ultraviolet laser pulses from resonant dispersive wave emission in a hollow capillary fibre	36
A general but still unknown characteristic of active oxygen evolution electrocatalysts	36
Targeting multidrug resistant Staphylococcus infections with bacterial histidine kinase inhibitors	36
Photolysis-driven bond activation by thorium and uranium tetraosmate polyhydride complexes	36
Unconventional gas-phase preparation of the prototype polycyclic aromatic hydrocarbon naphthalene (C10H8) via the reaction of benzyl (C7H7) and propa	36
In silico screening of LRRK2 WDR domain inhibitors using deep docking and free energy simulations	36
Kinetically controlled synthesis of rotaxane geometric isomers	35
Facile modification of phosphole-based aggregation-induced emission luminogens with sulfonyl isocyanates	35
Improving machine learning performance on small chemical reaction data with unsupervised contrastive pretraining	35
Noncovalent interaction guided selectivity of haloaromatic isomers in a flexible porous coordination polymer	35
Orally administered bismuth drug together with N-acetyl cysteine as a broad-spectrum anti-coronavirus cocktail therapy	35
Can range-separated functionals be optimally tuned to predict spectra and excited state dynamics in photoactive iron complexes?	34
Overall reaction mechanism of photocatalytic CO2 reduction on a Re(i)-complex catalyst unit of a Ru(ii)–Re(i) supramolecular photocatalyst	34
Synergistic effect of p-type and n-type dopants in semiconductors for efficient electrocatalytic water splitting	34
Iron-catalysed alkene and heteroarene H/D exchange by reversible protonation of iron-hydride intermediates	34
Wetting-enhanced adhesion of photo-polymerized supramolecular adhesives for both smooth and rough surfaces	34
NSPs: chromogenic linkers for fast, selective, and irreversible cysteine modification	34
An AND-gate bioluminescent probe for precise tumor imaging	34
Front cover	34
Supramolecular encapsulation of redox-active monomers to enable free-radical polymerisation	34
Intermolecular noncovalent interactions with carbon in solution	34
Photophysics and photochemistry of thermally activated delayed fluorescence emitters based on the multiple resonance effect: transient optical and electron paramagnetic resonance studies	34
CO reductive oligomerization by a divalent thulium complex and CO2-induced functionalization	34
Photochemistry of pyruvic acid is governed by photo-induced intermolecular electron transfer through hydrogen bonds	34
Non-destructive real-time monitoring and investigation of the self-assembly process using fluorescent probes	34
2D hexagonal assembly of a dipolar rotor with a close interval of 0.8 nm using a triptycene-based supramolecular scaffold	34
Programmable synthesis of well-defined, glycosylated iron(ii) supramolecular assemblies with multivalent protein-binding capabilities	33
Photosensitizer-singlet oxygen sensor conjugated silica nanoparticles for photodynamic therapy and bioimaging	33
Designer pseudopeptides: autofluorescent polygonal tubes via Phe-zipper and triple helix	33
Single-molecule detection of a terrylenediimide-based near-infrared emitter	33
Back cover	33
Isoacridone dyes with parallel reactivity from both singlet and triplet excited states for biphotonic catalysis and upconversion	33
Reactivity of 1,3-enyne MIDA boronates: exploration of novel 1,2-alkyne shift via gem-difluorination	33
Dual-emissive luminescence in OIHMH single crystals: tunable red-green emissions via Mn2+ doping and theoretical insights	33
A surface reconstruction route for increasingly improved photocatalytic H2O2 production using Sr2Bi3Ta2O11Cl	33
Four-step continuous-flow total synthesis of (−)-debromoflustramine B using a chiral heterogeneous Pd NP catalyst	33
An electric field-based approach for quantifying effective volumes and radii of chemically affected space	33
Back cover	33
Electron transport chain-inspired coordination polymers for macroscopic spatiotemporal scales of charge separation and transport in photocatalysis	33
An alternating copolymer of phenothiazine and ethylenedioxythiophene for perovskite solar cells: effects of flexible and rigid substituent alternation	33
Dynamic handedness inversion of self-organized helical superstructures enabled by novel thermally stable light-driven chiral hydrazone switches	33
Divergent total syntheses of pyrroloiminoquinone alkaloids enabled by the development of a Larock/Buchwald–Hartwig annulation/cyclization	32
Palladium and copper co-catalyzed chloro-arylation of gem-difluorostyrenes – use of a nitrite additive to suppress β-F elimination	32
Axially-chiral boramidine for detailed (chir)optical studies	32
Bromine radical release from a nickel-complex facilitates the activation of alkyl boronic acids: a boron selective Suzuki–Miyaura cross coupling	32
Front cover	32
Revealing the nature of covalently tethered distonic radical anions in the generation of heteroatom-centered radicals: evidence for the polarity-matching PCET pathway	32
Front cover	32
Closed-loop chemically recyclable covalent adaptive networks derived from elementary sulfur	32
A silylboronate-mediated strategy for cross-coupling of alkyl fluorides with aryl alkanes: mechanistic insights and scope expansion	32
Metal-free introduction of primary sulfonamide into electron-rich aromatics	32
Formation of a low-symmetry Pd8 molecular barrel employing a hetero donor tetradentate ligand, and its use in the binding and extraction of C70	32
Unified ionic and radical C-4 alkylation and arylation of pyridines	32
Ketone-functionalized conjugated organic polymers boost red-light-driven molecular oxygen-mediated oxygenation	32
A changeable critical state for a switchable photocurrent direction via the photo-electrochemical photocurrent polarity switching effect in BiFeO3 nanoparticulate films	32
Strategies to boost the electrochemical performance of bismuth anodes for potassium-ion batteries	32
Preparation of intrinsically fragile bent crystals	32
On-capillary alkylation micro-reactor: a facile strategy for proteo-metabolome profiling in the same single cells	31
Vortex fluidic induced mass transfer across immiscible phases	31
Confined dual Lewis acid centers for selective cascade C–C coupling and deoxygenation	31
Controlled, one-pot synthesis of recyclable poly(1,3-diene)-polyester block copolymers, catalyzed by yttrium β-diketiminate complexes	31
A review of frustrated Lewis pair enabled monoselective C–F bond activation	31
A senolysis-based theragnostic prodrug strategy towards chronic renal failure	31
Self-assembly of achiral building blocks into chiral cyclophanes using non-directional interactions	31
Free-atom-like d states beyond the dilute limit of single-atom alloys	31
Controllable mitochondrial aggregation and fusion by a programmable DNA binder	31
Unveiling the complex configurational landscape of the intralayer cavities in a crystalline carbon nitride	31
Water sensitivity of heteroepitaxial Cu-MOF films: dissolution and re-crystallization of 3D-oriented MOF superstructures	31
On the use of real-world datasets for reaction yield prediction	31
Unprecedented sesterterpenoids, orientanoids A–C: discovery, bioinspired total synthesis and antitumor immunity	31
Hierarchical covalent organic framework-foam for multi-enzyme tandem catalysis	31
A flexible data-free framework for structure-based de novo drug design with reinforcement learning	31
Block copolymer synthesis in ionic liquid via polymerisation-induced self-assembly: a convenient route to gel electrolytes	31
Theoretical prediction of a graphene-like 2D uranyl material with p-orbital antiferromagnetism	31
Zintl cluster supported low coordinate Rh(i) centers for catalytic H/D exchange between H2and D2	31
Development and application of decatungstate catalyzed C–H 18F- and 19F-fluorination, fluoroalkylation and beyond	31
The power of microdroplet photochemistry	31
Construction of a quaternary stereogenic center by asymmetric hydroformylation: a straightforward method to prepare chiral α-quaternary amino acids	30
BQ-AurIPr: a redox-active anticancer Au(i) complex that induces immunogenic cell death	30
In situ electrochemical regeneration of active 1,4-NADH for enzymatic lactic acid formation via concerted functions on Pt-modified TiO2/Ti	30
Observation of super-Nernstian proton-coupled electron transfer and elucidation of nature of charge carriers in a multiredox conjugated polymer	30
Stochastic assembly of biomacromolecular complexes: impact and implications on charge interpretation in native mass spectrometry	30
Precise synthesis of BN embedded perylene diimide oligomers for fast-charging and long-life potassium–organic batteries	30