Cell Death & Disease

Article	Citations
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons	1040
Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1	762
Multi-omics prediction of axillary treatment response and tumour microenvironment alterations in lymph node-positive luminal breast cancer	526
STK38-mediated feedback loop regulation of the hedgehog pathway governing tumor heterogeneity in renal papillary carcinoma	475
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	453
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer	409
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α	409
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish	391
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells	358
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea	327
Retraction Note: MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer	274
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats	270
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function	254
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3	239
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis	237
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3	213
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation	204
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication	204
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor	204
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation	201
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment	181
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation	179
Lactylation-drived TRIM29 induces invasive behavior and lymph node metastasis in gastric cancer via hnRNPA1-mediated Wnt/β-catenin pathway	178
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation	176
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7	167

Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice	167
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker	166
KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1	163
Correction: SNRPB promotes gastric cancer progression by regulating aberrant splicing of PUF60	154
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle	152
REP-1 deficiency induces aberrant mitochondrial metabolic rewiring from glycolysis to lipid oxidation in CHM disease	151
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD	146
KDM1A epigenetically enhances RAD51 expression to suppress the STING-associated anti-tumor immunity in esophageal squamous cell carcinoma	146
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis	140
Correction: SPHK1 promotes bladder cancer metastasis via PD-L2/c-Src/FAK signaling cascade	138
Stochasticity contributes to explaining minority and majority MOMP during apoptosis	136
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer	134
Mutant TDP-43 drives impairments in axonal transport and glycolysis in a mouse stem-cell-derived motor neuron model of amyotrophic lateral sclerosis (ALS)	134
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy	132
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model	124
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence	118
Glucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival	118
Metabolomic profiling delineates the role of adenosine in oocyte quality and embryonic development	117
Inhibition of RNA polymerase II-activating CDK9 and CDK12/13, but not of cell cycle relevant CDKs, induces apoptosis by downregulating the short-lived Bcl-2 proteins Mcl1 and Bfl1/A1	117
Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition	116
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer	116
NICD3 mediates pro-angiogenic effects through SMAD3/TGFBI axis in colorectal cancer	113
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition	112
USP13 promotes enzalutamide resistance by catalyzing depolyubiquitination of PCMT1 in prostate cancer	111
Transcription-dependent and -independent functions of Drosophila p53 isoforms in the induction of apoptosis and senescence-associated tumorigenesis	111
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications	109
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma	109
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way	108
Vitamin D receptor isoform VDRA suppresses hepatocellular tumorigenesis by restricting YAP nuclear localization	108
Loss of MLKL impairs abdominal aortic aneurysm development by attenuating smooth muscle cell necroptosis	105
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12	103
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis	102
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis	102
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity	102
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis	100
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma	98
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation	98
CircPSD3 aggravates tumor progression by maintaining TCA cycle and mitochondrial function via regulating SUCLG2 in thyroid carcinoma	97
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1	96
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma	95
FOXM1 induces therapy resistance and inhibits apoptosis in a variety of human cancers	95
ATRA upregulates OTUD6B to recruit CD8+ T cells to suppress colorectal liver metastasis by stabilizing DDX5/STAT3/CXCL11 axis	95
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC	93
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1	92
Complement receptor 3 (CR3)-dependent microglial synapse elimination drives Parkinson’s disease pathogenesis in systemic inflammation	91
TPI1 enhances gemcitabine resistance in bladder cancer by promoting autophagy through activating Beclin-1	90
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis	90
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice	88
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling	88
Identification and validation of NCOA5-ZCCHC3/FGF22 axis as a prognostic marker in lung adenocarcinoma migration and invasion	88

LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma	88
SOX4-BMI1 axis promotes non-small cell lung cancer progression and facilitates angiogenesis by suppressing ZNF24	86
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response	86
Astrocytic SCAP deletion ameliorates diabetes-associated cognitive impairment by suppressing microglial neuroinflammation and lipid droplet accumulation via the LCN2–24p3R–mTOR axis	86
Regulatory T cells in skeletal muscle repair and regeneration: recent insights	86
PIM kinase inhibition attenuates pro-tumoral and immunosuppressive functions of macrophages in classic Hodgkin lymphoma	86
Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders	85
Restoration of axon initial segment plasticity via chemogenetic activation rescues autism-related behaviors	85
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma	85
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma	85
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy	84
Selective killing of ALT-cancer cells by Withaferin-A involves destabilization of Rad51 and disruption of DNA repair	84
The N6-methyladenosine-mediated cLMNB1 degrades FGFR4 to overcome osimertinib resistance in non-small cell lung cancer	84
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury	84
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling	83
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC	83
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation	83
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review	82
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer	81
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6	80
Knockdown of Porf-2 restores visual function after optic nerve crush injury	80
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury	80
USAG-1 aggravates renal ischemia‒reperfusion injury via promoting GPX4 degradation-induced ferroptosis	80
Targeting FAM111B attenuates mitophagy and increases the sensitivity to lenvatinib treatment by increasing MFN2 stability in hepatocellular carcinoma	79
Retraction Note: Restoring BMP4 expression in vascular endothelial progenitors ameliorates maternal diabetes-induced apoptosis and neural tube defects	79
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer	79
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia	79
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation	79
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling	79
Proteasome inhibition as a potential therapeutic target in thymic cancer	78
VEGFR2 deletion increases susceptibility to photoreceptor degeneration through glial-neuronal interaction	77
A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins	77
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma	77
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila	77
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression	77
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway	77
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer	76
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis	76
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway	76
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization	76
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway	76
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity	76
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer	75
CAR-T therapy dilemma and innovative design strategies for next generation	74
Long non-coding RNAs in cancer glycolysis and metabolism: mechanisms and translational opportunities	74
Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma	74
Retraction Note: Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancer	73
Protein kinase G inhibition preserves photoreceptor viability and function in a new mouse model for autosomal dominant retinitis pigmentosa	73
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy	73
E3 Ubiquitin ligases Cbl-b and c-Cbl maintain the homeostasis of macrophages by regulating the M-CSF/M-CSFR signaling axis	72
Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction	72
Correction: LINC01016 promotes the malignant phenotype of endometrial cancer cells by regulating the miR-302a-3p/miR-3130-3p/NFYA/SATB1 axis	71
MicroRNA miR-1275 coordinately regulates AEA/LPA signals via targeting FAAH in lipid metabolism reprogramming of gastric cancer	71
Correction: MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis	71
Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells	70
Pharmacological activation of p53 induces dose-dependent changes in endothelial cell fate during angiogenic sprouting	70
14-3-3γ Knockdown promotes matrix mineralization in human mesenchymal stromal cells	70
Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death	69
Single-cell multi-omics analysis reveals cancer regulatory elements of transcriptional programs and clinical implications	69
Correction to: Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	69
Correction: CHIP-mediated ubiquitin degradation of BCAT1 regulates glioma cell proliferation and temozolomide sensitivity	68
The glycolytic enzyme PGK1 phosphorylates MORC2 to Confer radioresistance in pancreatic ductal adenocarcinoma	68
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis	68
Platelet aging and desialylation increase apoptotic priming and BCL-XL dependence	68
Correction: Proximity proteomics reveals OTUD6B regulation of stress granule dynamics through coalescence with VCP/p97	68
High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals	68
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation	68
Targeting the FNIP2-SERCA2b axis improves metabolic and mitochondrial defects in Ataxia Telangiectasia	67
Loss of RNF41 promotes bladder cancer metastasis through increasing NUDC stability to enhance tubulin polymerization	67
Correction: Mitochondrial quality control in diabetes mellitus and complications: molecular mechanisms and therapeutic strategies	66
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss	66
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer	65
Retraction Note: Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer	65
Nitroglycerin: a comprehensive review in cancer therapy	65
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer	65
Central Zika virus infection causes hypothalamic inflammation and persistent insulin resistance in adult mice	64
Retraction Note to: Expansion of monocytic myeloid-derived suppressor cells ameliorated intestinal inflammatory response by radiation through SOCS3 expression	64
DP103 as a critical modulator of Wnt signaling and cancer stemness: implications for precision treatment in triple negative breast cancer	64
The MYC-dependent lncRNA MB3 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5	64
Tryptophan metabolic gatekeeping in epithelial repair: GPR35-KLF5 circuitry decodes mucosal damage signals for repair programming	64

Cancer-associated fibroblasts expressing FSTL3 promote vasculogenic mimicry formation and drive colon cancer malignancy	64
CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling	63
Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors	63
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy	63
Inflammation impairs fertility and oocyte quality in systemic lupus erythematosus by triggering oxidative stress-mediated ferroptosis	63
Interplay between the RBP SYNCRIP and RNA methylation in determining sEV miRNA-cargo and function in cell-to-cell communication	63
TNFAIP2 promotes HIF1α transcription and breast cancer angiogenesis by activating the Rac1-ERK-AP1 signaling axis	63
mTOR inhibition enhances the antitumor efficacy of pan-RAF-MEK blockade by inhibiting the ATF4-MTHFD2 pathway	62
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208	62
USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescence	62
GPR107 promotes autophagy secretion in psoriatic keratinocytes by inhibiting BECN1 K48-linked ubiquitination	61
Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress	61
TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner	61
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia	60
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis	60
β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4	60
Beyond a waste product: lactate as a master metabolite dictating anti-tumor T-cell fate	60
RIPK3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis	60
Everolimus destabilizes thymidylate synthase via suppressing its O-GlcNAcylation and sensitizes HER2-negative breast cancer to fluorouracil	59
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy	59
Hepatic steatosis and pyroptosis are induced by the hepatitis B virus X protein via B56α-METTL3 interaction-mediated m6A modification of the NLRP3 mRNA	59
Targeting EHMT2 enhances NK cell maturation and antitumor activity	59
S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis	59
Metabolic gatekeepers: harnessing tumor-derived metabolites to optimize T cell-based immunotherapy efficacy in the tumor microenvironment	59
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10	59
The role of vitamin K and its antagonist in the process of ferroptosis-damaged RPE-mediated CNV	58
Critical analysis of translational potential of rodent models of white matter pathology across a wide spectrum of human diseases	58
Targeting FOXM1 regulates metabolic signatures through ROS-dependent JNK/Bmi1/Skp2 axis in human cutaneous T-cell lymphoma	58
Germline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells	58
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer	58
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism	58
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ	58
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice	58
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation	58
Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis	58
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function	58
Lactylation as a metabolic-epigenetic switch in cancer: dual roles in cell death resistance and therapeutic vulnerability	58
Trim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4+T cell activation in breast cancer	57
Activation of KIT signaling promotes early tumorigenesis through the AP-1 pathway in APC/TP53 double-knockout human colon organoids	57
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy	57
Androgen-targeted hsa_circ_0085121 encodes a novel protein and improves the development of prostate cancer through facilitating the activity of PI3K/Akt/mTOR pathway and enhancing AR-V7 alternative sp	56
USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma	56
STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection	56
The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogen	55
Acetylation-dependent USP7-TRIM25 axis drives oncogenic progression in non-small cell lung cancer	55
Dual Bcl-2/Bcl-xl inhibition via AZD0466 combines with immune checkpoint blockade to enhance anti-tumour activity	55
LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2	55
YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation	55
O-GlcNAcylation inhibition redirects the response of colon cancer cells to chemotherapy from senescence to apoptosis	54
Unraveling sex differences in age-related hippocampal decline: differential mitochondrial dysfunction, Lonp1-dependent mitochondrial proteostasis and mtROS production in aged C57BL/6 mice	54
Phagocytosis by retinal pigment epithelium and microglia does not affect vision restoration by P3HT nanoparticles in Retinitis pigmentosa	54
Systemic mechanisms of necrotic cell debris clearance	54
The emerging role of dendritic cells in the tumor microenvironment: from antigen presentation to targeted immunotherapy	54
NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy	54
Stanniocalcin 1 promotes lung metastasis of breast cancer by enhancing EGFR–ERK–S100A4 signaling	54
DDX5 deficiency drives non-canonical NF-κB activation and NRF2 expression, influencing sorafenib response and hepatocellular carcinoma progression	54
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications	54
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway	54
Matrix stiffness maintains bladder cancer stemness via integrin-nuclear skeleton axis	54
Opposing roles for GSK3β and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington’s disease	54
Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect	54
SARS-CoV-2 nonspike structural proteins hijack mucosa epithelial cell fate	53
Impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neurons	53
Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p	53
Oocyte-specific knockout of eIF2B subunits causes apoptosis of mouse oocytes within the early growing follicles via DNA damage and mitochondrial dysfunction	53
THOC3 interacts with YBX1 to promote lung squamous cell carcinoma progression through PFKFB4 mRNA modification	53
CAF-derived exosomal WEE2-AS1 facilitates colorectal cancer progression via promoting degradation of MOB1A to inhibit the Hippo pathway	53
The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m6A methylation: a novel mechanism early during radiation-induced liver injury	53
WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT	52
ACSL3 inhibits ferroptosis in gastric cancer through the activation of unfolded protein response following endoplasmic reticulum stress	52
A novel strategy to target metabolic dependencies in acute myeloid leukemia	52
Transcriptome reprogramming of Epstein-Barr virus infected epithelial and B cells reveals distinct host-virus interaction profiles	52
Inhibition of ATM enhances the immunogenicity of triple-negative breast cancer by promoting MHC-I expression	52
A human Staufen1 BAC transgenic mouse exhibits abnormal autophagy and neurodegeneration across the central nervous system	52
NKD1 promotes the progression and 5-FU resistance of colorectal cancer via the Wnt/β-catenin signaling	52
OTUD6B-mediated K48 deubiquitination of FXR1 forms a positive feedback loop activating MEK2/ERK signaling in colorectal cancer liver metastasis	51
Endothelial cell-derived RSPO3 activates Gαi1/3-Erk signaling and protects neurons from ischemia/reperfusion injury	51
Novel FABP4+C1q+ macrophages enhance antitumor immunity and associated with response to neoadjuvant pembrolizumab and chemotherapy in NSCLC via AMPK/JAK/STAT axis	51
Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases	51
Deficiency of G9a boosts muscle regeneration through IL13/Musclin-mediated crosstalk between macrophage and myofiber	51
LINC00924-induced fatty acid metabolic reprogramming facilitates gastric cancer peritoneal metastasis via hnRNPC-regulated alternative splicing of Mnk2	51
GDPPH1 induces cell cycle arrest by downregulation of CDK4/Cyclin D1 via the m6A-METTL14-YTHDF2 axis, attenuating glioblastoma progression	51
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer	51
The duality of CXCR3 in glioblastoma: unveiling autocrine and paracrine mechanisms for novel therapeutic approaches	51
Mitochondrial-endoplasmic reticulum interactions in lung diseases	51
Correction to: Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells	50
Deltex E3 ubiquitin ligase 2 potentiates STING-mediated type I interferon response by K63-linked ubiquitination	50
LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1	50
SOX4-STAT6-MTHFD2 axis drives hepatocellular carcinoma progression and treatment resistance	50
In vivo restoration of dystrophin expression in mdx mice using intra-muscular and intra-arterial injections of hydrogel microsphere carriers of exon skipping antisense oligonucleotides	50
Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein	50
Inhibition of the immunoproteasome modulates innate immunity to ameliorate muscle pathology of dysferlin-deficient BlAJ mice	50
Retraction Note: Identification of protein kinase inhibitors to reprogram breast cancer cells	49
Correction: SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis	49
Retraction Note: Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration	49