Cell Death & Disease

Article	Citations
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons	923
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer	700
Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1	557
Multi-omics prediction of axillary treatment response and tumour microenvironment alterations in lymph node-positive luminal breast cancer	536
STK38-mediated feedback loop regulation of the hedgehog pathway governing tumor heterogeneity in renal papillary carcinoma	480
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	425
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α	422
Proteasome inhibition as a potential therapeutic target in thymic cancer	383
Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition	370
Complement receptor 3 (CR3)-dependent microglial synapse elimination drives Parkinson’s disease pathogenesis in systemic inflammation	311
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer	307
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish	286
Transcription-dependent and -independent functions of Drosophila p53 isoforms in the induction of apoptosis and senescence-associated tumorigenesis	258
A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins	239
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma	228
Stochasticity contributes to explaining minority and majority MOMP during apoptosis	221
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells	215
Long non-coding RNAs in cancer glycolysis and metabolism: mechanisms and translational opportunities	194
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea	194
Glucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival	188
Retraction Note: MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer	188
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats	181
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function	180
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3	176
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia	166

ATRA upregulates OTUD6B to recruit CD8+ T cells to suppress colorectal liver metastasis by stabilizing DDX5/STAT3/CXCL11 axis	165
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway	163
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis	160
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α	159
FOXM1 induces therapy resistance and inhibits apoptosis in a variety of human cancers	156
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation	156
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response	155
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization	154
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation	154
Retraction Note: Restoring BMP4 expression in vascular endothelial progenitors ameliorates maternal diabetes-induced apoptosis and neural tube defects	151
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer	137
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis	137
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3	137
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity	135
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor	133
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma	131
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC	131
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice	130
Knockdown of Porf-2 restores visual function after optic nerve crush injury	129
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication	126
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation	121
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation	119
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment	118
USP13 promotes enzalutamide resistance by catalyzing depolyubiquitination of PCMT1 in prostate cancer	117
Vitamin D receptor isoform VDRA suppresses hepatocellular tumorigenesis by restricting YAP nuclear localization	116
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis	111
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer	111
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation	109
PIM kinase inhibition attenuates pro-tumoral and immunosuppressive functions of macrophages in classic Hodgkin lymphoma	109
Lactylation-drived TRIM29 induces invasive behavior and lymph node metastasis in gastric cancer via hnRNPA1-mediated Wnt/β-catenin pathway	109
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way	108
TPI1 enhances gemcitabine resistance in bladder cancer by promoting autophagy through activating Beclin-1	108
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis	107
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation	106
CircPSD3 aggravates tumor progression by maintaining TCA cycle and mitochondrial function via regulating SUCLG2 in thyroid carcinoma	106
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation	105
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression	104
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7	100
FAK mediates LPS-induced inflammatory lung injury through interacting TAK1 and activating TAK1-NFκB pathway	99
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model	98
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis	96
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma	96
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy	96
Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice	96
Targeting FAM111B attenuates mitophagy and increases the sensitivity to lenvatinib treatment by increasing MFN2 stability in hepatocellular carcinoma	95
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling	94
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker	93
KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1	92
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1	89
Correction: SNRPB promotes gastric cancer progression by regulating aberrant splicing of PUF60	89

TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway	88
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle	88
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling	85
KDM1A epigenetically enhances RAD51 expression to suppress the STING-associated anti-tumor immunity in esophageal squamous cell carcinoma	85
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC	85
REP-1 deficiency induces aberrant mitochondrial metabolic rewiring from glycolysis to lipid oxidation in CHM disease	85
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD	85
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer	85
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis	84
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1	84
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence	84
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications	83
Correction: SPHK1 promotes bladder cancer metastasis via PD-L2/c-Src/FAK signaling cascade	83
Mutant TDP-43 drives impairments in axonal transport and glycolysis in a mouse stem-cell-derived motor neuron model of amyotrophic lateral sclerosis (ALS)	83
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12	82
CAR-T therapy dilemma and innovative design strategies for next generation	82
USAG-1 aggravates renal ischemia‒reperfusion injury via promoting GPX4 degradation-induced ferroptosis	82
SOX4-BMI1 axis promotes non-small cell lung cancer progression and facilitates angiogenesis by suppressing ZNF24	81
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review	81
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma	80
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila	80
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer	80
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma	80
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer	80
Restoration of axon initial segment plasticity via chemogenetic activation rescues autism-related behaviors	79
Inhibition of RNA polymerase II-activating CDK9 and CDK12/13, but not of cell cycle relevant CDKs, induces apoptosis by downregulating the short-lived Bcl-2 proteins Mcl1 and Bfl1/A1	78
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis	78
TRAIL protects the immature lung from hyperoxic injury	78
The N6-methyladenosine-mediated cLMNB1 degrades FGFR4 to overcome osimertinib resistance in non-small cell lung cancer	78
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma	77
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition	77
SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction	77
Loss of MLKL impairs abdominal aortic aneurysm development by attenuating smooth muscle cell necroptosis	76
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6	76
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy	76
Regulatory T cells in skeletal muscle repair and regeneration: recent insights	75
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury	75
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma	74
Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders	74
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury	74
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway	74
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling	74
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity	73
Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model	73
p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-1	73
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy	72
Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma	72
Retraction Note: Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancer	72
Protein kinase G inhibition preserves photoreceptor viability and function in a new mouse model for autosomal dominant retinitis pigmentosa	71
Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction	71
E3 Ubiquitin ligases Cbl-b and c-Cbl maintain the homeostasis of macrophages by regulating the M-CSF/M-CSFR signaling axis	70
Hepatic steatosis and pyroptosis are induced by the hepatitis B virus X protein via B56α-METTL3 interaction-mediated m6A modification of the NLRP3 mRNA	70
The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogen	69
DDX5 deficiency drives non-canonical NF-κB activation and NRF2 expression, influencing sorafenib response and hepatocellular carcinoma progression	69
Androgen-targeted hsa_circ_0085121 encodes a novel protein and improves the development of prostate cancer through facilitating the activity of PI3K/Akt/mTOR pathway and enhancing AR-V7 alternative sp	69
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function	69
MicroRNA miR-1275 coordinately regulates AEA/LPA signals via targeting FAAH in lipid metabolism reprogramming of gastric cancer	69
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice	68
The MYC-dependent lncRNA MB3 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5	68
Correction: MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis	68
Trim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4+T cell activation in breast cancer	68
Correction: LINC01016 promotes the malignant phenotype of endometrial cancer cells by regulating the miR-302a-3p/miR-3130-3p/NFYA/SATB1 axis	68
Dual Bcl-2/Bcl-xl inhibition via AZD0466 combines with immune checkpoint blockade to enhance anti-tumour activity	67
Matrix stiffness maintains bladder cancer stemness via integrin-nuclear skeleton axis	67
Pharmacological activation of p53 induces dose-dependent changes in endothelial cell fate during angiogenic sprouting	67
Targeting FOXM1 regulates metabolic signatures through ROS-dependent JNK/Bmi1/Skp2 axis in human cutaneous T-cell lymphoma	67
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia	66
Phagocytosis by retinal pigment epithelium and microglia does not affect vision restoration by P3HT nanoparticles in Retinitis pigmentosa	66
The role of vitamin K and its antagonist in the process of ferroptosis-damaged RPE-mediated CNV	66
14-3-3γ Knockdown promotes matrix mineralization in human mesenchymal stromal cells	65
Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells	65
Single-cell multi-omics analysis reveals cancer regulatory elements of transcriptional programs and clinical implications	65
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ	65
Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death	64
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis	64
mTOR inhibition enhances the antitumor efficacy of pan-RAF-MEK blockade by inhibiting the ATF4-MTHFD2 pathway	64
Germline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells	64
Correction to: Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	64
O-GlcNAcylation inhibition redirects the response of colon cancer cells to chemotherapy from senescence to apoptosis	64
SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin	64

USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma	63
Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis	63
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy	63
Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress	63
YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation	63
Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors	62
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer	62
β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4	62
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation	62
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism	62
Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect	62
Central Zika virus infection causes hypothalamic inflammation and persistent insulin resistance in adult mice	62
High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals	62
USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescence	61
Platelet aging and desialylation increase apoptotic priming and BCL-XL dependence	61
CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling	61
RIPK3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis	61
Unraveling sex differences in age-related hippocampal decline: differential mitochondrial dysfunction, Lonp1-dependent mitochondrial proteostasis and mtROS production in aged C57BL/6 mice	61
STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection	61
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer	61
Stanniocalcin 1 promotes lung metastasis of breast cancer by enhancing EGFR–ERK–S100A4 signaling	61
Nitroglycerin: a comprehensive review in cancer therapy	60
The glycolytic enzyme PGK1 phosphorylates MORC2 to Confer radioresistance in pancreatic ductal adenocarcinoma	60
NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy	60
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation	60
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway	60
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208	58
Loss of RNF41 promotes bladder cancer metastasis through increasing NUDC stability to enhance tubulin polymerization	57
Opposing roles for GSK3β and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington’s disease	57
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss	57
Targeting the FNIP2-SERCA2b axis improves metabolic and mitochondrial defects in Ataxia Telangiectasia	57
Retraction Note: Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer	56
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer	56
Correction: Mitochondrial quality control in diabetes mellitus and complications: molecular mechanisms and therapeutic strategies	56
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia	56
Novel roles of luteinizing hormone (LH) in tissue regeneration-associated functions in endometrial stem cells	56
Correction to: Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma	56
Tryptophan metabolic gatekeeping in epithelial repair: GPR35-KLF5 circuitry decodes mucosal damage signals for repair programming	56
TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner	56
Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1	56
Acetylation-dependent USP7-TRIM25 axis drives oncogenic progression in non-small cell lung cancer	56
Correction: CHIP-mediated ubiquitin degradation of BCAT1 regulates glioma cell proliferation and temozolomide sensitivity	55
Correction: Proximity proteomics reveals OTUD6B regulation of stress granule dynamics through coalescence with VCP/p97	55
Metabolic gatekeepers: harnessing tumor-derived metabolites to optimize T cell-based immunotherapy efficacy in the tumor microenvironment	55
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy	54
Ascitic fluid shear stress in concert with hepatocyte growth factor drive stemness and chemoresistance of ovarian cancer cells via the c-Met-PI3K/Akt-miR-199a-3p signaling pathway	54
Retraction Note to: Expansion of monocytic myeloid-derived suppressor cells ameliorated intestinal inflammatory response by radiation through SOCS3 expression	54
Cancer-associated fibroblasts expressing FSTL3 promote vasculogenic mimicry formation and drive colon cancer malignancy	54
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10	54
Everolimus destabilizes thymidylate synthase via suppressing its O-GlcNAcylation and sensitizes HER2-negative breast cancer to fluorouracil	54
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications	53
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer	53
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis	53
LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2	53
Lactylation as a metabolic-epigenetic switch in cancer: dual roles in cell death resistance and therapeutic vulnerability	53
Critical analysis of translational potential of rodent models of white matter pathology across a wide spectrum of human diseases	53
TNFAIP2 promotes HIF1α transcription and breast cancer angiogenesis by activating the Rac1-ERK-AP1 signaling axis	53
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy	53
S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis	53
The emerging role of dendritic cells in the tumor microenvironment: from antigen presentation to targeted immunotherapy	53
SNHG25 facilitates SNORA50C accumulation to stabilize HDAC1 in neuroblastoma cells	52
LncRNA IRAR regulates chemokines production in tubular epithelial cells thus promoting kidney ischemia-reperfusion injury	52
Stabilization of MCL-1 by E3 ligase TRAF4 confers radioresistance	52
Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases	52
Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p	52
Retraction Note: RUNX3-regulated circRNA METTL3 inhibits colorectal cancer proliferation and metastasis via miR-107/PER3 axis	52
Systemic mechanisms of necrotic cell debris clearance	52
Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line	51
Role of reactive oxygen species in regulating 27-hydroxycholesterol-induced apoptosis of hematopoietic progenitor cells and myeloid cell lines	51
Declined RTN3 stabilizes DHCR7 to induce cholesterol-dependent tumor progression and MEK inhibitors insensitivity in thyroid cancer	51
Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis	51
CENPT prevents renal cell carcinoma against ferroptosis by enhancing the synthesis of glutathione	51
Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer	51
Correction to: Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells	51
Transcriptome reprogramming of Epstein-Barr virus infected epithelial and B cells reveals distinct host-virus interaction profiles	51
Correction: SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis	51
CAF-derived exosomal WEE2-AS1 facilitates colorectal cancer progression via promoting degradation of MOB1A to inhibit the Hippo pathway	51
SARS-CoV-2 nonspike structural proteins hijack mucosa epithelial cell fate	51
O-GlcNAcylation of YAP1 promotes lung transplant ischemia-reperfusion injury via binding to HIF1α transcription factor and activating autophagy and mitophagy	51
Neddylation-mediated degradation of hnRNPA2B1 contributes to hypertriglyceridemia pancreatitis	51
Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo	51
Inhibition of the immunoproteasome modulates innate immunity to ameliorate muscle pathology of dysferlin-deficient BlAJ mice	51
PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation	50
NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis	50
The potential impact of RNA splicing abnormalities on immune regulation in endometrial cancer	50
LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1	50
Non-canonical functions of spliceosome components in cancer progression	50
Deficiency of SIAH1 promotes the formation of filopodia by increasing the accumulation of FASN in liver cancer	50
HMGA2 alleviates ferroptosis by promoting GPX4 expression in pancreatic cancer cells	50
CYP8B1 inhibits hepatocellular carcinoma progression by repressing PAK4 transcription through inhibition of nuclear translocation of u-STAT1	50
RBM4 regulates cellular senescence via miR1244/SERPINE1 axis	50
Claudin-7 is essential for the maintenance of colonic stem cell homoeostasis via the modulation of Wnt/Notch signalling	50
Mechanistic insights into SIRT7 and EZH2 regulation of cisplatin resistance in bladder cancer cells	50
SOX4-STAT6-MTHFD2 axis drives hepatocellular carcinoma progression and treatment resistance	50
A novel strategy to target metabolic dependencies in acute myeloid leukemia	49