Cell Death & Disease

Article	Citations
Detection of immunogenic cell death and its relevance for cancer therapy	566
Regulated cell death pathways in doxorubicin-induced cardiotoxicity	348
RNA-based therapeutics: an overview and prospectus	244
Advances in the pathogenesis of psoriasis: from keratinocyte perspective	227
CircRNA hsa_circRNA_104348 promotes hepatocellular carcinoma progression through modulating miR-187-3p/RTKN2 axis and activating Wnt/β-catenin pathway	218
CircRNAs: role in human diseases and potential use as biomarkers	216
Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?	200
Scutellarin ameliorates pulmonary fibrosis through inhibiting NF-κB/NLRP3-mediated epithelial–mesenchymal transition and inflammation	181
Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI	178
Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer	168
GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis	168
Characterization of ferroptosis in kidney tubular cell death under diabetic conditions	161
Alpha-synuclein in Parkinson’s disease and other synucleinopathies: from overt neurodegeneration back to early synaptic dysfunction	147
Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance	145
Interaction between macrophages and ferroptosis	140
PD-L1 degradation pathway and immunotherapy for cancer	140
Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells	136
Mitochondrial autophagy: molecular mechanisms and implications for cardiovascular disease	128
MYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma	127
The role of m6A modification in physiology and disease	125
Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity	124
STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway	122
Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction	120
TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca2+/CaMKII/Nrf2 signaling pathway	119
Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers	117

Exosomes and breast cancer drug resistance	116
Which cell death modality wins the contest for photodynamic therapy of cancer?	115
AMPK agonist alleviate renal tubulointerstitial fibrosis via activating mitophagy in high fat and streptozotocin induced diabetic mice	112
The emerging role of ferroptosis in intestinal disease	111
The mechanism of m6A methyltransferase METTL3-mediated autophagy in reversing gefitinib resistance in NSCLC cells by β-elemene	109
DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism	108
Cancer-derived exosomal HSPC111 promotes colorectal cancer liver metastasis by reprogramming lipid metabolism in cancer-associated fibroblasts	107
Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines	107
Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation	105
GPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis	105
LncRNA RP11-89 facilitates tumorigenesis and ferroptosis resistance through PROM2-activated iron export by sponging miR-129-5p in bladder cancer	105
Arsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway	104
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis	103
The interaction between ferroptosis and inflammatory signaling pathways	103
Inhibition of keratinocyte ferroptosis suppresses psoriatic inflammation	102
The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis	102
Nrf2 attenuates ferroptosis-mediated IIR-ALI by modulating TERT and SLC7A11	102
METTL14-regulated PI3K/Akt signaling pathway via PTEN affects HDAC5-mediated epithelial–mesenchymal transition of renal tubular cells in diabetic kidney disease	101
Endoplasmic reticulum stress-mediated cell death in liver injury	100
Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells	100
Evidences for lipid involvement in SARS-CoV-2 cytopathogenesis	99
Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?	96
STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS)	95
MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma	95
SOX2 promotes chemoresistance, cancer stem cells properties, and epithelial–mesenchymal transition by β-catenin and Beclin1/autophagy signaling in colorectal cancer	94
Autophagy: Regulator of cell death	94
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury	93
The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders	93
Sitagliptin activates the p62–Keap1–Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury	93
Adipose tissue aging: mechanisms and therapeutic implications	93
Targeting ferroptosis in acute kidney injury	92
Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies	92
A cross-talk between epithelium and endothelium mediates human alveolar–capillary injury during SARS-CoV-2 infection	92
Ferroptosis: the potential value target in atherosclerosis	91
WNT/β-catenin-suppressed FTO expression increases m6A of c-Myc mRNA to promote tumor cell glycolysis and tumorigenesis	90
Liproxstatin-1 attenuates unilateral ureteral obstruction-induced renal fibrosis by inhibiting renal tubular epithelial cells ferroptosis	90
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	89
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation	88
Discovery of a novel ferroptosis inducer-talaroconvolutin A—killing colorectal cancer cells in vitro and in vivo	87
Age-severity matched cytokine profiling reveals specific signatures in Covid-19 patients	86
Cancer-secreted exosomal miR-21-5p induces angiogenesis and vascular permeability by targeting KRIT1	86
Mutant p53 in cancer: from molecular mechanism to therapeutic modulation	85
The redox language in neurodegenerative diseases: oxidative post-translational modifications by hydrogen peroxide	84
METTL14 suppresses pyroptosis and diabetic cardiomyopathy by downregulating TINCR lncRNA	84
Double-edge sword roles of iron in driving energy production versus instigating ferroptosis	83
TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells	82
YTHDC1 mitigates ischemic stroke by promoting Akt phosphorylation through destabilizing PTEN mRNA	82
Ionizing radiation results in a mixture of cellular outcomes including mitotic catastrophe, senescence, methuosis, and iron-dependent cell death	82
p27 controls autophagic vesicle trafficking in glucose-deprived cells via the regulation of ATAT1-mediated microtubule acetylation	82
ER stress and UPR in Alzheimer’s disease: mechanisms, pathogenesis, treatments	81

SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype	81
Programmed cell death in atherosclerosis and vascular calcification	79
HucMSC-derived exosomes delivered BECN1 induces ferroptosis of hepatic stellate cells via regulating the xCT/GPX4 axis	78
mtDNA-STING pathway promotes necroptosis-dependent enterocyte injury in intestinal ischemia reperfusion	78
Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2α/ATF4/CHOP pathway in breast cancer	78
N6-methyladenosine modification of circCUX1 confers radioresistance of hypopharyngeal squamous cell carcinoma through caspase1 pathway	76
LncRNA-MIAT promotes thyroid cancer progression and function as ceRNA to target EZH2 by sponging miR-150-5p	76
ALKBH5 suppresses tumor progression via an m6A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma	76
The emerging roles of neutrophil extracellular traps in wound healing	76
Small-molecule inhibition of APE1 induces apoptosis, pyroptosis, and necroptosis in non-small cell lung cancer	75
A long way to go: caspase inhibitors in clinical use	75
Cell-cycle arrest and senescence in TP53-wild type renal carcinoma by enhancer RNA-P53-bound enhancer regions 2 (p53BER2) in a p53-dependent pathway	74
A novel circular RNA, circXPO1, promotes lung adenocarcinoma progression by interacting with IGF2BP1	74
Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis	74
Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-β/Smad2/3 pathway	74
M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway	73
LncRNA kcnq1ot1 promotes lipid accumulation and accelerates atherosclerosis via functioning as a ceRNA through the miR-452-3p/HDAC3/ABCA1 axis	73
m6A methylated EphA2 and VEGFA through IGF2BP2/3 regulation promotes vasculogenic mimicry in colorectal cancer via PI3K/AKT and ERK1/2 signaling	73
LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination	71
CD36 promotes NLRP3 inflammasome activation via the mtROS pathway in renal tubular epithelial cells of diabetic kidneys	71
Extracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion	71
Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling	69
Stromal cells in the tumor microenvironment: accomplices of tumor progression?	69
Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1	69
RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m6A-dependent manner	69
Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis	68
Calcium and TRPV4 promote metastasis by regulating cytoskeleton through the RhoA/ROCK1 pathway in endometrial cancer	67
The diversified role of mitochondria in ferroptosis in cancer	67
Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity	67
A new risk factor indicator for papillary thyroid cancer based on immune infiltration	66
Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction	66
The role of the PI3K/AKT signalling pathway in the corneal epithelium: recent updates	66
Circ_0008542 in osteoblast exosomes promotes osteoclast-induced bone resorption through m6A methylation	66
STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway	66
YTHDF1 promotes breast cancer cell growth, DNA damage repair and chemoresistance	66
METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1	66
BNIP3L/NIX-mediated mitophagy: molecular mechanisms and implications for human disease	65
Lipid peroxidation and the subsequent cell death transmitting from ferroptotic cells to neighboring cells	65
RNA m6A reader YTHDF2 facilitates lung adenocarcinoma cell proliferation and metastasis by targeting the AXIN1/Wnt/β-catenin signaling	64
Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts	64
LncRNA linc00312 suppresses radiotherapy resistance by targeting DNA-PKcs and impairing DNA damage repair in nasopharyngeal carcinoma	64
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway	64
Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma	63
Cancer-associated fibroblast-derived CXCL11 modulates hepatocellular carcinoma cell migration and tumor metastasis through the circUBAP2/miR-4756/IFIT1/3 axis	63
M2 macrophage-derived exosomal long non-coding RNA AGAP2-AS1 enhances radiotherapy immunity in lung cancer by reducing microRNA-296 and elevating NOTCH2	63
Cancer cell metabolic reprogramming: a keystone for the response to immunotherapy	63
Quercetin promotes in vitro maturation of oocytes from humans and aged mice	63
Circulating mitochondrial DNA-triggered autophagy dysfunction via STING underlies sepsis-related acute lung injury	62
NLPR3 inflammasome inhibition alleviates hypoxic endothelial cell death in vitro and protects blood–brain barrier integrity in murine stroke	62
Targeted P2X7/NLRP3 signaling pathway against inflammation, apoptosis, and pyroptosis of retinal endothelial cells in diabetic retinopathy	62
Interactions between gastric microbiota and metabolites in gastric cancer	61
The crosstalk between HIFs and mitochondrial dysfunctions in cancer development	61
Interactions between m6A modification and miRNAs in malignant tumors	61
Regulatory pathways and drugs associated with ferroptosis in tumors	61
Exosome-derived ENO1 regulates integrin α6β4 expression and promotes hepatocellular carcinoma growth and metastasis	61
Zinc transporter ZIP7 is a novel determinant of ferroptosis	61
YAP inhibits autophagy and promotes progression of colorectal cancer via upregulating Bcl-2 expression	60
Zeb1-induced metabolic reprogramming of glycolysis is essential for macrophage polarization in breast cancer	60
Protein lysine crotonylation: past, present, perspective	60
A gene toolbox for monitoring autophagy transcription	60
Autophagy mediates an amplification loop during ferroptosis	59
Isoliquiritigenin prevents hyperglycemia-induced renal injuries by inhibiting inflammation and oxidative stress via SIRT1-dependent mechanism	59
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages	59
Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis	59
Single cell transcriptional zonation of human psoriasis skin identifies an alternative immunoregulatory axis conducted by skin resident cells	59
LncRNA LINC00472 regulates cell stiffness and inhibits the migration and invasion of lung adenocarcinoma by binding to YBX1	59
Tumor exosome promotes Th17 cell differentiation by transmitting the lncRNA CRNDE-h in colorectal cancer	59
MIEF2 reprograms lipid metabolism to drive progression of ovarian cancer through ROS/AKT/mTOR signaling pathway	58
CircRAB11FIP1 promoted autophagy flux of ovarian cancer through DSC1 and miR-129	58
Exosomal circ_DLGAP4 promotes diabetic kidney disease progression by sponging miR-143 and targeting ERBB3/NF-κB/MMP-2 axis	57
Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer	57
CISD3 inhibition drives cystine-deprivation induced ferroptosis	57
High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy	56
Induction of ferroptosis in human nasopharyngeal cancer cells by cucurbitacin B: molecular mechanism and therapeutic potential	56
Potential role of senescent macrophages in radiation-induced pulmonary fibrosis	56
Effects of short-chain fatty acids in inhibiting HDAC and activating p38 MAPK are critical for promoting B10 cell generation and function	56
Irisin protects against vascular calcification by activating autophagy and inhibiting NLRP3-mediated vascular smooth muscle cell pyroptosis in chronic kidney disease	55
Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway	55
Necroptosis is active and contributes to intestinal injury in a piglet model with lipopolysaccharide challenge	55
LDHA induces EMT gene transcription and regulates autophagy to promote the metastasis and tumorigenesis of papillary thyroid carcinoma	54

Adipocyte death triggers a pro-inflammatory response and induces metabolic activation of resident macrophages	54
Deciphering the tRNA-derived small RNAs: origin, development, and future	54
SIRT6 promotes angiogenesis and hemorrhage of carotid plaque via regulating HIF-1α and reactive oxygen species	54
Tumor-derived exosomal components: the multifaceted roles and mechanisms in breast cancer metastasis	54
LncRNA H19 governs mitophagy and restores mitochondrial respiration in the heart through Pink1/Parkin signaling during obesity	54
Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells	53
Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice	53
Osteocrin, a novel myokine, prevents diabetic cardiomyopathy via restoring proteasomal activity	53
Inhibiting multiple forms of cell death optimizes ganglion cells survival after retinal ischemia reperfusion injury	52
Inhibiting NLRP3 inflammasome activation prevents copper-induced neuropathology in a murine model of Wilson’s disease	52
Emerging understanding of apoptosis in mediating mesenchymal stem cell therapy	52
Tumour-derived exosomal lncRNA-SOX2OT promotes bone metastasis of non-small cell lung cancer by targeting the miRNA-194-5p/RAC1 signalling axis in osteoclasts	52
C5aR1-positive neutrophils promote breast cancer glycolysis through WTAP-dependent m6A methylation of ENO1	52
The metabolic flexibility of quiescent CSC: implications for chemotherapy resistance	51
Plasma-activated medium induces ferroptosis by depleting FSP1 in human lung cancer cells	51
Interplay between p53 and non-coding RNAs in the regulation of EMT in breast cancer	51
Senescent neutrophils-derived exosomal piRNA-17560 promotes chemoresistance and EMT of breast cancer via FTO-mediated m6A demethylation	51
Linking the YTH domain to cancer: the importance of YTH family proteins in epigenetics	51
Exosomes in ovarian cancer ascites promote epithelial–mesenchymal transition of ovarian cancer cells by delivery of miR-6780b-5p	51
Semaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis	51
BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism	51
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming	51
Impacts and mechanisms of metabolic reprogramming of tumor microenvironment for immunotherapy in gastric cancer	50
Sirtuin 3 regulates mitochondrial protein acetylation and metabolism in tubular epithelial cells during renal fibrosis	50
Kartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis	50
Long non-coding RNA PAARH promotes hepatocellular carcinoma progression and angiogenesis via upregulating HOTTIP and activating HIF-1α/VEGF signaling	50
Cancer associated fibroblast–derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis	50
Sestrin2 protects dendrite cells against ferroptosis induced by sepsis	49
STAT3/LINC00671 axis regulates papillary thyroid tumor growth and metastasis via LDHA-mediated glycolysis	49
The RNA m6A writer WTAP in diseases: structure, roles, and mechanisms	49
Ferroptosis as a potential target for cancer therapy	49
Involvement of FSP1-CoQ10-NADH and GSH-GPx-4 pathways in retinal pigment epithelium ferroptosis	49
Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation	49
Protectin DX restores Treg/Th17 cell balance in rheumatoid arthritis by inhibiting NLRP3 inflammasome via miR-20a	49
Prognostic correlations with the microbiome of breast cancer subtypes	49
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease	49
Iron metabolism and ferroptosis in type 2 diabetes mellitus and complications: mechanisms and therapeutic opportunities	49
Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo	49
Exosomal transfer of tumor-associated macrophage-derived hsa_circ_0001610 reduces radiosensitivity in endometrial cancer	49
Adult mesenchymal stem cell ageing interplays with depressed mitochondrial Ndufs6	48
Peroxiredoxin 4 protects against ovarian ageing by ameliorating d-galactose-induced oxidative damage in mice	48
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood–brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis	48
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy	48
The double-edged functions of necroptosis	48
Cathepsin B in programmed cell death machinery: mechanisms of execution and regulatory pathways	48
Hypoxia induces sorafenib resistance mediated by autophagy via activating FOXO3a in hepatocellular carcinoma	48
Oxidative stress activates NORAD expression by H3K27ac and promotes oxaliplatin resistance in gastric cancer by enhancing autophagy flux via targeting the miR-433-3p	48
Comparison of the major cell populations among osteoarthritis, Kashin–Beck disease and healthy chondrocytes by single-cell RNA-seq analysis	48
Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion	48
Enhanced glycolysis in granulosa cells promotes the activation of primordial follicles through mTOR signaling	47
M2-like macrophages exert hepatoprotection in acute-on-chronic liver failure through inhibiting necroptosis-S100A9-necroinflammation axis	47
Interleukin-38 ameliorates poly(I:C) induced lung inflammation: therapeutic implications in respiratory viral infections	47
Second generation androgen receptor antagonists and challenges in prostate cancer treatment	47
Nrf2 activation induces mitophagy and reverses Parkin/Pink1 knock down-mediated neuronal and muscle degeneration phenotypes	47
Cdc25A inhibits autophagy-mediated ferroptosis by upregulating ErbB2 through PKM2 dephosphorylation in cervical cancer cells	46
CPT1A-mediated fatty acid oxidation promotes cell proliferation via nucleoside metabolism in nasopharyngeal carcinoma	46
The effect of extracellular vesicles on the regulation of mitochondria under hypoxia	46
A novel 3’tRNA-derived fragment tRF-Val promotes proliferation and inhibits apoptosis by targeting EEF1A1 in gastric cancer	46
Autophagic secretion of HMGB1 from cancer-associated fibroblasts promotes metastatic potential of non-small cell lung cancer cells via NFκB signaling	45
Hsa_circ_0007456 regulates the natural killer cell-mediated cytotoxicity toward hepatocellular carcinoma via the miR-6852-3p/ICAM-1 axis	45
HIF-1α-activated long non-coding RNA KDM4A-AS1 promotes hepatocellular carcinoma progression via the miR-411-5p/KPNA2/AKT pathway	45
The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging	45
Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis	45
Macrophage polarization and metabolism in atherosclerosis	45
Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury	45
Endothelial progenitor cells-derived exosomal microRNA-21-5p alleviates sepsis-induced acute kidney injury by inhibiting RUNX1 expression	45
Emerging role of RNA modification N6-methyladenosine in immune evasion	45
The androgen receptor/filamin A complex as a target in prostate cancer microenvironment	44
N6-methyladenosine demethylase FTO promotes growth and metastasis of gastric cancer via m6A modification of caveolin-1 and metabolic regulation of mitochondrial dynamics	44
Circular RNA UBE2Q2 promotes malignant progression of gastric cancer by regulating signal transducer and activator of transcription 3-mediated autophagy and glycolysis	44
CircTHBS1 drives gastric cancer progression by increasing INHBA mRNA expression and stability in a ceRNA- and RBP-dependent manner	44
Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs	44
Fibrillar α-synuclein induces neurotoxic astrocyte activation via RIP kinase signaling and NF-κB	44
Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer	44
c-MYC-induced long noncoding RNA MEG3 aggravates kidney ischemia–reperfusion injury through activating mitophagy by upregulation of RTKN to trigger the Wnt/β-catenin pathway	44
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy	44
Tunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria	43
Liquid biopsy in gastric cancer: predictive and prognostic biomarkers	43
Hippo-YAP/MCP-1 mediated tubular maladaptive repair promote inflammation in renal failed recovery after ischemic AKI	43
Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells	43
Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis	43
SOX9-activated FARSA-AS1 predetermines cell growth, stemness, and metastasis in colorectal cancer through upregulating FARSA and SOX9	43
EGR2-mediated regulation of m6A reader IGF2BP proteins drive RCC tumorigenesis and metastasis via enhancing S1PR3 mRNA stabilization	43
Pyroptosis inhibition improves the symptom of acute myocardial infarction	43
The N6-methyladenosine demethylase ALKBH5 negatively regulates the osteogenic differentiation of mesenchymal stem cells through PRMT6	43
Ferroptosis: a double-edged sword mediating immune tolerance of cancer	43
Targeting ferroptosis as a vulnerability in pulmonary diseases	43
Circular RNA hsa_circ_0000277 sequesters miR-4766-5p to upregulate LAMA1 and promote esophageal carcinoma progression	43
Cell death in head and neck cancer pathogenesis and treatment	43
Colorectal cancer-associated fibroblasts promote metastasis by up-regulating LRG1 through stromal IL-6/STAT3 signaling	43
Expanding the role of proteasome homeostasis in Parkinson’s disease: beyond protein breakdown	42
Monocytic MDSC mobilization promotes tumor recurrence after liver transplantation via CXCL10/TLR4/MMP14 signaling	42
Role of noncoding RNA in drug resistance of prostate cancer	42
P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells	42
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation	42